Compounds > carbon tetrachloride
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carbon tetrachloride and 2-acetylaminofluorene

carbon tetrachloride has been researched along with 2-acetylaminofluorene in 50 studies

Research

Studies (50)

TimeframeStudies, this research(%)All Research%
pre-199023 (46.00)18.7374
1990's13 (26.00)18.2507
2000's8 (16.00)29.6817
2010's6 (12.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Kozuka, S; Sassa, R1
Farber, E; Gruenstein, M; Parker, S1
Columbano, A; Coni, P; Curto, M; Faa, G; Giacomini, L; Ledda-Columbano, GM; Sarma, DS1
Dianzani, MU; Pani, P; Tessitore, L1
Farber, E; Gelderblom, WC; Marasas, WF; Semple, E1
Blankenship, LJ; Clawson, GA; Rhame, JG; Wilkinson, DS1
Abdellatif, AG; Nilsson, R; Préat, V; Roberfroid, M; Vamecq, J1
Barbason, H; Castelain, P; Deleener, A; Kirsch-Volders, M1
Hara, A; Iwata, H; Mori, H; Mori, Y; Niwa, K; Tanaka, T; Yoshimi, N1
Furihata, C; Matsushima, T; Sawada, S1
Ahluwalia, MB; Farber, E; Moslen, MT1
Brambilla, G; Ghia, M; Marinari, UM; Martelli, A; Mereto, E1
Becker, RA; Planche-Martel, G1
Eskelson, CD; Mufti, SI; Sipes, IG; Szebeni, J; Watson, RR1
de Gerlache, J; Lans, M; Préat, V; Roberfroid, M; Taper, H1
de Gerlache, J; Deleener, A; Kirsch-Volders, M; Lans, M1
Fujiwara, M; Kobayashi, M; Nagashima, H; Nakatsukasa, H; Sakata, T; Shiota, T; Takei, N; Watanabe, A1
de Gerlache, J; Lans, M; Pector, JC; Préat, V; Roberfroid, M; Taper, H1
Hagiwara, A; Hasegawa, R; Ito, N; Shirai, T; Tatematsu, M; Tsuda, H1
Sakata, T1
Groothuis, GM; Hardonk, MJ; Meijer, DK; Weitering, JG1
Farber, E; Ghoshal, AK; Medline, A; Mullen, B1
Groothuis, GM; Hardonk, MJ; Meijer, DK1
Groothuis, GM; Hardonk, MJ; Keulemans, KP; Meijer, DK; Mulder, D; Weitering, JG1
Sidransky, H; Verney, E1
Besbris, HJ; Cohen, AM; Wortzman, MS1
Hasegawa, R; Imaida, K; Ito, N; Murasaki, G; Tatematsu, M1
Castelain, P; Ghahroudi, MA; Kirsch-Volders, M; Van Goethem, F1
Akai, H; Andoh, N; Kobayashi, Y; Konishi, Y; Nakae, D; Ohashi, K; Satoh, H; Tsutsumi, M1
Michalopoulos, GK; Petersen, BE; Zajac, VF2
Goff, JP; Greenberger, JS; Michalopoulos, GK; Petersen, BE1
Boggs, SS; Bowen, WC; Goff, JP; Greenberger, JS; Mars, WM; Murase, N; Patrene, KD; Petersen, BE; Sullivan, AK1
Rajalakshmi, S; Rao, PM; Sarma, DS; Yusuf, A1
Danz, M; Fuchs, U; Klinger, W; Lucas, N; Lupp, A; Tralls, M1
Butterworth, BE; Mirsalis, JC1
Abel, S; Galendo, D; Gelderblom, WC; Marasas, WF; Swanevelder, S; Wild, CP1
Espandiari, P; Glauert, HP; Lee, EY; Lehmler, HJ; Robertson, LW; Srinivasan, C1
Haga, H; Hattori, E; Ishii, R; Ito, JI; Karasawa, T; Kawata, S; Misawa, K; Okumoto, K; Saito, K; Saito, T; Sanjo, M; Sugahara, K; Suzuki, A; Togashi, H1
Bollito, E; Tessitore, L1
Itoh, T; Mitsumori, K; Moto, M; Sakai, H; Takahashi, M1
Corcelle, V; Gauthier, BR; Gjinovci, A; Stieger, B; Wollheim, CB1
Chang, MH; Chen, DS; Chien, CT; Chiou, LL; Chiu, CC; Chou, SH; Huang, GT; Lee, HS1
Chen, CH; Chiou, LL; Chiu, CC; Chou, SH; Huang, GT; Lee, CZ; Lee, HS; Sheu, JC1
Hayashi, H; Mitsumori, K; Shibutani, M; Shimamoto, K; Suzuki, T; Tawfeeq, MM1
Brouillet, A; Chobert, MN; Couchie, D; Fourcot, A; Laperche, Y; Mavier, P; Zafrani, ES1
Bugyik, E; Dezső, K; Nagy, P; Paku, S; Papp, V; Pávai, Z; Rókusz, A; Szabó, V1
Chen, G; Chen, J; Duan, Y; Li, X; Liu, C; Liu, P; Mu, Y; Ren, S; Xu, Y; Zern, M; Zhang, H; Zhang, X; Zhou, Y1
Chen, YH; Huang, YJ; Hung, TM; Lee, PH; Lin, YC; Wu, YM1

Other Studies

50 other study(ies) available for carbon tetrachloride and 2-acetylaminofluorene

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Acceleration of hepatocarcinogenesis of 2,7-bis(acetamido)fluorene by carbon tetrachloride and time relation of treatment.
    Gan, 1976, Volume: 67, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinoma, Hepatocellular; Female; Fluorenes; Hyperplasia; Liver Neoplasms; Male; Mice; Neoplasms, Experimental; Sex Factors; Time Factors

1976
The resistance of putative premalignant liver cell populations, hyperplastic nodules, to the acute cytotoxic effects of some hepatocarcinogens.
    Cancer research, 1976, Volume: 36, Issue:11 Pt 1

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Cell Transformation, Neoplastic; Dimethylnitrosamine; DNA; Drug Resistance; Ethionine; Hyperplasia; Liver; Liver Neoplasms; Male; Precancerous Conditions; Proteins; Rats; Rats, Inbred F344; RNA

1976
Mitogen-induced liver hyperplasia does not substitute for compensatory regeneration during promotion of chemical hepatocarcinogenesis.
    Carcinogenesis, 1992, Volume: 13, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Division; Diethylnitrosamine; gamma-Glutamyltransferase; Hyperplasia; Lead; Liver; Liver Neoplasms, Experimental; Liver Regeneration; Male; Nitrates; Orotic Acid; Phenobarbital; Rats; Rats, Inbred Strains

1992
Choline enhances acetylaminofluorene promotion of liver carcinogenesis in female but not in male rats.
    Carcinogenesis, 1992, Volume: 13, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Choline; Diethylnitrosamine; Drug Synergism; Female; Liver; Liver Neoplasms, Experimental; Male; Rats; Rats, Inbred Strains; Sex Characteristics

1992
The cancer-initiating potential of the fumonisin B mycotoxins.
    Carcinogenesis, 1992, Volume: 13, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogenicity Tests; Carcinogens, Environmental; Cells, Cultured; DNA Repair; Fumonisins; Liver Neoplasms, Experimental; Male; Mycotoxins; Rats; Rats, Inbred F344

1992
Nuclear enlargement induced by hepatocarcinogens alters ploidy.
    Cancer research, 1992, Mar-01, Volume: 52, Issue:5

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Nucleus; Dimethylnitrosamine; Diploidy; Liver; Male; Polyploidy; Rats; Rats, Inbred Strains; Thioacetamide

1992
Peroxisome proliferation and modulation of rat liver carcinogenesis by 2,4-dichlorophenoxyacetic acid, 2,4,5-trichlorophenoxyacetic acid, perfluorooctanoic acid and nafenopin.
    Carcinogenesis, 1990, Volume: 11, Issue:11

    Topics: 2-Acetylaminofluorene; 2,4-Dichlorophenoxyacetic Acid; 2,4,5-Trichlorophenoxyacetic Acid; Animals; Caprylates; Carbon Tetrachloride; Diethylnitrosamine; Enzyme Induction; Fluorocarbons; Liver Neoplasms, Experimental; Male; Microbodies; Nafenopin; Rats; Rats, Inbred Strains

1990
Cell population kinetics and ploidy rate of early focal lesions during hepatocarcinogenesis in the rat.
    British journal of cancer, 1989, Volume: 60, Issue:6

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Count; Diethylnitrosamine; DNA; Liver; Liver Neoplasms, Experimental; Male; Mitosis; Ploidies; Rats; Rats, Inbred Strains

1989
Induction of altered hepatocellular foci of hamster for a possible short-term assay for carcinogens.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 63, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Body Weight; Carbon Tetrachloride; Carcinogens; Cricetinae; Liver; Male; Mesocricetus; Organ Size

1989
In vivo short-term assays of repair and replication of rat liver DNA.
    Journal of cancer research and clinical oncology, 1989, Volume: 115, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Dimethylnitrosamine; DNA; DNA Repair; DNA Replication; Liver; Male; Rats; Rats, Inbred F344

1989
1,2-Dibromoethane initiation of hepatic nodules in Sprague-Dawley rats selected with Solt-Farber system.
    Archives of toxicology, 1985, Volume: 58, Issue:2

    Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Ethylene Dibromide; gamma-Glutamyltransferase; Hydrocarbons, Brominated; Liver; Liver Diseases; Rats; Rats, Inbred Strains

1985
Induction and promotion of gamma-glutamyltranspeptidase-positive foci in the rat liver by methylglyoxal.
    Japanese journal of cancer research : Gann, 1988, Volume: 79, Issue:6

    Topics: 2-Acetylaminofluorene; Aldehydes; Animals; Carbon Tetrachloride; gamma-Glutamyltransferase; Liver Neoplasms, Experimental; Male; Precancerous Conditions; Pyruvaldehyde; Rats; Rats, Inbred F344

1988
Enhanced O6-methylguanine-DNA alkyltransferase activity in rat liver nodules.
    Cancer letters, 1986, Volume: 31, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; DNA Repair; Female; Kinetics; Liver; Liver Neoplasms, Experimental; Male; Methyltransferases; Mice; O(6)-Methylguanine-DNA Methyltransferase; Precancerous Conditions; Pregnancy; Rats; Rats, Inbred F344

1986
Inhibition of ethanol induced ethane exhalation by carcinogenic pretreatment of rats 12 months earlier.
    Life sciences, 1986, Dec-29, Volume: 39, Issue:26

    Topics: 2-Acetylaminofluorene; Animals; Breath Tests; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Drug Interactions; Ethane; Ethanol; Lipid Peroxides; Liver; Male; Rats; Rats, Inbred Strains; Time Factors

1986
Influence of the duration and the delay of administration of phenobarbital on its modulating effect on rat hepatocarcinogenesis.
    Carcinogenesis, 1987, Volume: 8, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Drug Administration Schedule; Liver Neoplasms; Liver Neoplasms, Experimental; Phenobarbital; Rats

1987
Nucleolar changes during the first steps of experimental hepatocarcinogenesis in rats.
    Cancer genetics and cytogenetics, 1985, Volume: 17, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Nucleolus; Cell Transformation, Neoplastic; Cocarcinogenesis; Diethylnitrosamine; Hepatectomy; Histocytochemistry; Liver; Liver Neoplasms; Male; Phenobarbital; Precancerous Conditions; Rats; Rats, Inbred Strains

1985
Effect of azathioprine and carbon tetrachloride on induction of hyperplastic liver nodule and hepatocellular carcinoma by diethylnitrosamine and N-2-fluorenylacetamide in rats.
    Annals of the New York Academy of Sciences, 1983, Volume: 417

    Topics: 2-Acetylaminofluorene; Aniline Hydroxylase; Animals; Azathioprine; Carbon Tetrachloride; Diethylnitrosamine; Drug Interactions; gamma-Glutamyltransferase; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Nitrosamines; Rats; Rats, Inbred Strains

1983
[Promoting effect of portacaval anastomosis in experimental hepatic carcinogenesis].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1984, Volume: 178, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Diethylnitrosamine; Liver Neoplasms, Experimental; Male; Portacaval Shunt, Surgical; Rats; Rats, Inbred Strains

1984
Induction of hyperplastic liver nodules in hepatectomized rats treated with 3'-methyl-4-dimethylaminoazobenzene, benzo[a]pyrene or phenobarbital before or after exposure to N-2-fluorenylacetamide.
    Gan, 1982, Volume: 73, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Benzo(a)pyrene; Benzopyrenes; Carbon Tetrachloride; Hepatectomy; Hyperplasia; Liver; Liver Neoplasms; Male; Methyldimethylaminoazobenzene; p-Dimethylaminoazobenzene; Phenobarbital; Rats; Rats, Inbred F344

1982
Effects of carbon tetrachloride and azathioprine on diethylnitrosamine and N-2-fluorenylacetamide-induced hyperplastic liver nodule and hepatocellular carcinoma.
    Acta medica Okayama, 1984, Volume: 38, Issue:6

    Topics: 2-Acetylaminofluorene; Aniline Hydroxylase; Animals; Azathioprine; Carbon Tetrachloride; Diethylnitrosamine; Drug Interactions; Hyperplasia; Isoenzymes; Leucine Transaminase; Liver; Liver Neoplasms, Experimental; Male; Nitrosamines; Ornithine Decarboxylase; Rats; Rats, Inbred Strains; Transaminases

1984
Heterogeneity of rat hepatocytes in transport and hepatic binding of asialoalkaline phosphatase studied after induction of selective acinar damage by N-hydroxy-2-acetylaminofluorene and carbon tetrachloride.
    Biochemical pharmacology, 1983, Sep-15, Volume: 32, Issue:18

    Topics: 2-Acetylaminofluorene; Alkaline Phosphatase; Animals; Asialoglycoproteins; Bile; Biological Transport; Carbon Tetrachloride; Dogs; Glycoproteins; Histocytochemistry; Hydroxyacetylaminofluorene; Intestines; Kinetics; Liver; Male; Rats; Rats, Inbred Strains

1983
Sequential analysis of hepatic carcinogenesis. Regeneration of liver after carbon tetrachloride-induced liver necrosis when hepatocyte proliferation is inhibited by 2-acetylaminofluorene.
    Laboratory investigation; a journal of technical methods and pathology, 1983, Volume: 48, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Division; Liver; Liver Neoplasms; Liver Regeneration; Male; Necrosis; Rats; Rats, Inbred F344

1983
Morphological studies on selective acinar liver damage by N-hydroxy-2-acetylaminofluorene and carbon tetrachloride.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 322, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Histocytochemistry; Hydroxyacetylaminofluorene; Liver; Male; Microscopy, Electron; Rats; Rats, Inbred Strains

1983
Heterogeneity of rat hepatocytes in bile acid and DBSP transport studied after induction of selective acinar damage by N-hydroxy-2-acetylaminofluorene and carbon tetrachloride.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 322, Issue:4

    Topics: 2-Acetylaminofluorene; Animals; Bile Acids and Salts; Biological Transport; Bromthymol Blue; Carbon Tetrachloride; Hydroxyacetylaminofluorene; In Vitro Techniques; Liver; Male; Perfusion; Rats; Rats, Inbred Strains; Thymol

1983
Acute effects of selected hepatotoxic agents on polyribosomes and protein synthesis in the livers of rats fed purified diets containing hepatocarcinogens.
    Experimental and molecular pathology, 1982, Volume: 36, Issue:1

    Topics: 2-Acetylaminofluorene; Acute Disease; Animals; Carbon Tetrachloride; Carcinogens; Chemical and Drug Induced Liver Injury; Dactinomycin; Diet; Ethionine; Hydrocortisone; Liver Neoplasms, Experimental; Methyldimethylaminoazobenzene; Polyribosomes; Protein Biosynthesis; Puromycin; Rats; Rats, Inbred Strains; Saline Solution, Hypertonic; Sparsomycin; Thioacetamide; Time Factors

1982
Effect of dietary selenium on the interaction between 2-acetylaminofluorene and rat liver DNA in vivo.
    Cancer research, 1980, Volume: 40, Issue:8 Pt 1

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Diet; DNA; DNA Repair; Glutathione Peroxidase; Hydrolysis; Lipid Metabolism; Liver; Male; Models, Chemical; Oxidation-Reduction; Peroxides; Rats; Selenium

1980
Effects of various promoters on the induction of hyperplastic nodules in rat liver.
    Gan, 1980, Volume: 71, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Hyperplasia; Liver; Liver Neoplasms; Male; Organ Specificity; Rats; Saccharin; Tetradecanoylphorbol Acetate

1980
Frequency and DNA content of micronuclei in rat parenchymal liver cells during experimental hepatocarcinogenesis.
    Carcinogenesis, 1993, Volume: 14, Issue:11

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Nucleus; Diethylnitrosamine; DNA; Liver; Liver Neoplasms, Experimental; Male; Micronuclei, Chromosome-Defective; Micronucleus Tests; Mitotic Index; Phenobarbital; Rats; Rats, Wistar

1993
Involvement of 8-hydroxyguanine formation in the initiation of rat liver carcinogenesis by low dose levels of N-nitrosodiethylamine.
    Cancer research, 1997, Apr-01, Volume: 57, Issue:7

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Colchicine; Diethylnitrosamine; Dose-Response Relationship, Drug; gamma-Glutamyltransferase; Guanine; Kidney; Linear Models; Liver Neoplasms; Lung; Male; Myocardium; Pancreas; Rats; Rats, Inbred F344; Risk Assessment; Time Factors

1997
Bile ductular damage induced by methylene dianiline inhibits oval cell activation.
    The American journal of pathology, 1997, Volume: 151, Issue:4

    Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Aniline Compounds; Animals; Bile Ducts; Carbon Tetrachloride; Carcinogens; Cell Division; Drug Interactions; Epithelium; Hepatectomy; Lethal Dose 50; Liver; Male; Rats; Rats, Inbred F344

1997
Hepatic oval cells express the hematopoietic stem cell marker Thy-1 in the rat.
    Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:2

    Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Antibodies, Monoclonal; Biomarkers; Bromodeoxyuridine; Carbon Tetrachloride; Flow Cytometry; Fluorescent Antibody Technique, Indirect; gamma-Glutamyltransferase; Hepatectomy; Immunohistochemistry; Keratins; Liver; Male; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Thy-1 Antigens

1998
Hepatic oval cell activation in response to injury following chemically induced periportal or pericentral damage in rats.
    Hepatology (Baltimore, Md.), 1998, Volume: 27, Issue:4

    Topics: 2-Acetylaminofluorene; alpha-Fetoproteins; Animals; Carbon Tetrachloride; Cell Division; DNA; Lethal Dose 50; Liver; Male; Propanols; Rats; Rats, Inbred F344; RNA, Messenger

1998
Bone marrow as a potential source of hepatic oval cells.
    Science (New York, N.Y.), 1999, May-14, Volume: 284, Issue:5417

    Topics: 2-Acetylaminofluorene; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Cell Differentiation; Cell Division; Dipeptidyl Peptidase 4; DNA-Binding Proteins; Epithelial Cells; Female; Hematopoietic Stem Cells; In Situ Hybridization; Liver; Liver Regeneration; Liver Transplantation; Male; Nuclear Proteins; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Rats, Inbred Lew; Sex-Determining Region Y Protein; Stem Cells; Transcription Factors; Y Chromosome

1999
Development of resistance during the early stages of experimental liver carcinogenesis.
    Carcinogenesis, 1999, Volume: 20, Issue:8

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Hepatectomy; Liver Neoplasms, Experimental; Male; Orotic Acid; Phenotype; Precancerous Conditions; Rats; Rats, Inbred F344

1999
Transplantation of fetal liver tissue suspension into the spleens of adult syngenic rats: effects of various mitogens and cytotoxins on cytochrome P450 (P450) isoforms expression and on P450 mediated monooxygenase functions.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1999, Volume: 51, Issue:4-5

    Topics: 2-Acetylaminofluorene; 7-Alkoxycoumarin O-Dealkylase; Animals; Bromobenzenes; Carbon Tetrachloride; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Ethylmorphine-N-Demethylase; Fetal Tissue Transplantation; Fluorenes; Isoenzymes; Liver; Liver Transplantation; Mitogens; Propanols; Rats; Rats, Inbred F344; Spleen

1999
Detection of unscheduled DNA synthesis in hepatocytes isolated from rats treated with genotoxic agents: an in vivo- in vitro assay for potential carcinogens and mutagens.
    Carcinogenesis, 1980, Volume: 1, Issue:7

    Topics: 2-Acetylaminofluorene; Animals; Autoradiography; Carbon Tetrachloride; Carcinogens; Cell Nucleus; Cytoplasm; Dimethylnitrosamine; DNA; DNA Repair; Dose-Response Relationship, Drug; Hepatocytes; Kinetics; Male; Mutagens; Rats; Rats, Inbred F344; Thymidine; Tritium

1980
Cancer initiation by fumonisin B(1) in rat liver--role of cell proliferation.
    Cancer letters, 2001, Aug-28, Volume: 169, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carboxylic Acids; Carcinogens; Cell Division; Dose-Response Relationship, Drug; Fumonisins; Hepatocytes; Lipid Peroxidation; Liver; Male; Neoplasms; Rats; Rats, Inbred F344; Thiobarbituric Acid Reactive Substances; Time Factors

2001
Initiating activity of 4-chlorobiphenyl metabolites in the resistant hepatocyte model.
    Toxicological sciences : an official journal of the Society of Toxicology, 2004, Volume: 79, Issue:1

    Topics: 2-Acetylaminofluorene; Adenoma, Liver Cell; Administration, Oral; Animals; Biphenyl Compounds; Body Weight; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Drug Administration Schedule; Drug Evaluation, Preclinical; gamma-Glutamyltransferase; Hydroxylation; Injections, Intraperitoneal; Intubation, Intratracheal; Liver; Liver Neoplasms, Experimental; Male; Models, Biological; Organ Size; Quinones; Rats; Rats, Inbred F344; Time Factors

2004
Characteristics of rat bone marrow cells differentiated into a liver cell lineage and dynamics of the transplanted cells in the injured liver.
    Journal of gastroenterology, 2006, Volume: 41, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Bone Marrow Cells; Bone Marrow Transplantation; Carbon Tetrachloride; Cell Differentiation; Cells, Cultured; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Fibroblast Growth Factors; Gene Expression; Hepatocyte Growth Factor; Hepatocytes; Immunohistochemistry; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spleen

2006
Early induction of TGF-beta1 through a fasting-re-feeding regimen promotes liver carcinogenesis by a sub-initiating dose of diethylnitrosamine.
    Cell proliferation, 2006, Volume: 39, Issue:2

    Topics: 2-Acetylaminofluorene; Animals; Apoptosis; bcl-2-Associated X Protein; Carbon Tetrachloride; Carcinogens; Diethylnitrosamine; Eating; Fasting; Liver Cirrhosis, Experimental; Liver Neoplasms, Experimental; Male; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Inbred F344; Transforming Growth Factor beta; Transforming Growth Factor beta1; Up-Regulation

2006
Liver initiation activity of norfloxacin but not nalidixic acid, pipemidic acid, and ciprofloxacin on in vivo short-term liver initiation assay in rats.
    Toxicology, 2006, May-15, Volume: 222, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Anti-Infective Agents; Carbon Tetrachloride; Carcinogens; Ciprofloxacin; Glutathione Transferase; Liver; Male; Nalidixic Acid; Norfloxacin; Pipemidic Acid; Rats; Rats, Inbred F344

2006
Characterization of two distinct liver progenitor cell subpopulations of hematopoietic and hepatic origins.
    Experimental cell research, 2006, Sep-10, Volume: 312, Issue:15

    Topics: 2-Acetylaminofluorene; Animals; Antigens, Differentiation; Bone Marrow; Carbon Tetrachloride; Cells, Cultured; Female; Hematopoietic Stem Cells; Hepatocytes; Immunohistochemistry; Liver; Liver Regeneration; Male; Mice; Rats; Rats, Sprague-Dawley; Stem Cells; Thy-1 Antigens

2006
Characterization of cytokeratin 19-positive hepatocyte foci in the regenerating rat liver after 2-AAF/CCl4 injury.
    Histochemistry and cell biology, 2007, Volume: 128, Issue:3

    Topics: 2-Acetylaminofluorene; Administration, Oral; alpha-Fetoproteins; Animals; Carbon Tetrachloride; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Hepatocytes; Immunochemistry; Keratin-19; Liver; Liver Regeneration; Male; Rats; Rats, Inbred F344; Staining and Labeling

2007
Global gene expression profiling reveals a key role of CD44 in hepatic oval-cell reaction after 2-AAF/CCl4 injury in rodents.
    Histochemistry and cell biology, 2009, Volume: 132, Issue:5

    Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Carbon Tetrachloride; Gene Expression Profiling; Gene Expression Regulation; Hyaluronan Receptors; Immunochemistry; Liver; Liver Regeneration; Male; Rats; Rats, Inbred F344; Reverse Transcriptase Polymerase Chain Reaction

2009
Evaluation of in vivo genotoxic potential of fenofibrate in rats subjected to two-week repeated oral administration.
    Archives of toxicology, 2011, Volume: 85, Issue:8

    Topics: 2-Acetylaminofluorene; Administration, Oral; Animals; Carbon Tetrachloride; Comet Assay; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Fenofibrate; Gene Expression Regulation; Hepatectomy; Hypolipidemic Agents; Liver; Male; PPAR alpha; Rats; Rats, Inbred F344

2011
Liver precursor cells increase hepatic fibrosis induced by chronic carbon tetrachloride intoxication in rats.
    Laboratory investigation; a journal of technical methods and pathology, 2012, Volume: 92, Issue:1

    Topics: 2-Acetylaminofluorene; Actins; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Carbon Tetrachloride; Epithelial-Mesenchymal Transition; Keratin-19; Liver; Liver Cirrhosis, Experimental; Male; Rats; Rats, Sprague-Dawley; Stem Cells; Transforming Growth Factor beta

2012
Expansion of hepatic stem cell compartment boosts liver regeneration.
    Stem cells and development, 2014, Jan-01, Volume: 23, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Hepatocytes; Liver; Liver Neoplasms; Liver Regeneration; Male; Rats; Rats, Inbred F344; Stem Cells

2014
Hepatic Progenitor Cells Contribute to the Progression of 2-Acetylaminofluorene/Carbon Tetrachloride-Induced Cirrhosis via the Non-Canonical Wnt Pathway.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: 2-Acetylaminofluorene; Animals; Carbon Tetrachloride; Cell Differentiation; Female; Inflammation; Liver; Liver Cirrhosis; Myofibroblasts; Rats; Rats, Inbred F344; Stem Cells; Wnt Signaling Pathway

2015
A critical role of autophagy in regulating the mesenchymal transition of ductular cells in liver cirrhosis.
    Scientific reports, 2019, 07-23, Volume: 9, Issue:1

    Topics: 2-Acetylaminofluorene; Animals; Autophagy; Carbon Tetrachloride; Disease Models, Animal; Epithelial-Mesenchymal Transition; Hepatic Stellate Cells; Hepatocytes; Humans; Liver; Liver Cirrhosis; Rats

2019