carbon monoxide has been researched along with nadp in 343 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 267 (77.84) | 18.7374 |
| 1990's | 42 (12.24) | 18.2507 |
| 2000's | 27 (7.87) | 29.6817 |
| 2010's | 6 (1.75) | 24.3611 |
| 2020's | 1 (0.29) | 2.80 |
| Authors | Studies |
|---|---|
| Chance, B; Fisher, AB; Furia, L | 1 |
| Coon, HG; Gelboin, HV; Whitlock, JP | 1 |
| Iwasaki, K; Kato, R; Noguchi, N; Shiraga, T | 1 |
| Juchau, MR; Lee, QP; Symms, KG; Zachariah, PK | 1 |
| Juchau, MR; Mirkin, DL; Zachariah, PK | 1 |
| Ishimaru, A; Yamazaki, I | 1 |
| Kato, R; Sugiura, M | 1 |
| Bloemendal, H; de Waal, R; Henderson, PT; van de Ven, WJ; Vermorken, AJ | 1 |
| Aronson, I; Ivanetich, KM; Katz, ID | 1 |
| Jonsson, J | 1 |
| Furukawa, T; Karashima, D; Shigematsu, A; Takahashi, S | 1 |
| Gillette, JR; Krishna, G; Sipes, IG | 1 |
| Fulco, AJ; Hare, RS; Matson, RS | 1 |
| Deutschmann, G; Mansuy, D; Nastainczyk, W; Ullrich, V; Wolf, CR | 1 |
| Estabrook, RW; Werringloer, J | 1 |
| Cavallin-Ståhl, E; Jönsson, GI; Lundh, B | 1 |
| Cerniglia, CE; Gibson, DT | 1 |
| Farese, RV; Prudente, WJ | 1 |
| Durst, F; Feyereisen, R | 1 |
| Arabian, A; Delvin, EE; Glorieux, FH | 1 |
| Guengerich, FP | 1 |
| Dvorchik, BH; Hartman, RD; Marietta, MP; Vesell, ES; Weisz, J | 1 |
| Fevold, HR; Slanina, SM; Wilson, PL | 1 |
| Dey, AC; Senciall, IR | 1 |
| Katsuki, H; Nishino, T; Osumi, T | 1 |
| Iamkovoĭ, VI; Liakhovich, VV; Pospelova, LN; Tsyrlov, IB; Vaĭner, LM | 1 |
| Fujioka, M; Miura, R; Miyake, Y; Okamoto, M; Yamano, T | 1 |
| Bloemendal, H; Goos, CM; Henderson, PT; Vermorken, AJ | 1 |
| Gutmann, HR; Kaplan, E | 1 |
| Feller, DR; Fowble, JW; Miller, DD; Son, OS | 1 |
| Kamataki, T; Kato, R; Sugiura, M; Yamazoe, Y | 1 |
| Kraus, P | 1 |
| Dave, CV; Gurtoo, HL | 1 |
| Gelboin, HV; Leutz, JC; Wiebel, FJ | 1 |
| Schremmer Lockmiller, JM; Wykle, RL | 1 |
| Kawalek, JC; Lu, AY | 1 |
| Beckett, AH; Dajani, RM; Gorrod, JW | 1 |
| Dalezios, JI; Hsieh, DP; Krieger, RI; Salhab, AS | 1 |
| Wiebel, FJ | 1 |
| Roach, MK | 1 |
| Fulco, AJ; Hare, RS | 1 |
| Matsubara, T; Nakamura, Y; Tochino, Y | 1 |
| Grudin, R; Moldèus, P; Orrenius, S; Vadi, H | 1 |
| Berman, MC; Ivanetich, KM; Kench, JE | 1 |
| Juchau, MR; Zachariah, PK | 1 |
| Kappus, H; Remmer, H | 1 |
| Abreu-Greenberg, M; Busbee, DL; Cantrell, ET; Guyden, J | 1 |
| Ellin, A; Orrenius, S | 1 |
| Dalal, NS; Shi, X | 1 |
| Ellis, MK; Foster, PM | 1 |
| Kanakubo, Y; Kitada, M; Komiya, M; Nakasa, H; Ohmori, S; Rikihisa, T | 1 |
| Cho, AK; Kumagai, Y; Schmitz, DA | 1 |
| Boucher, JL; Delaforge, M; Genet, A; Henry, Y; Mansuy, D; Vadon, S | 1 |
| Araki, J; Masubuchi, Y; Narimatsu, S; Suzuki, T | 1 |
| Gescher, A; Griffin, RJ; Nicholls, D | 1 |
| Dennis, MW; Kolattukudy, PE | 1 |
| Kirk, DN; Latif, SA; Smith, KE | 1 |
| Choe, WT; Clawson, GA; Hatem, CL | 1 |
| Downum, KR; Gillman, MJ; Stevenson, DK; Vreman, HJ | 1 |
| Endo, T; Hara, S; Kano, S; Kuriiwa, F | 1 |
| Chen, NQ; Holtzman, JL; Srivastava, SP | 1 |
| Beaune, P; Descatoire, V; Labbe, G; Larrey, D; Letteron, P; Pessayre, D | 1 |
| Heller, W; Koch, U; Kühnl, T; Wellmann, E | 1 |
| Cridland, JS; Huang, CY; Ivanetich, KM | 1 |
| Kurebayashi, H | 1 |
| Gibson, GG; Ioannides, C; Manno, M | 1 |
| Bettger, WJ; Bray, TM; Kubow, S | 1 |
| Broekman, MJ; Islam, N; Marcus, AJ; Safier, LB; Ullman, HL; von Schacky, C | 1 |
| Pezacka, E; Wood, HG | 1 |
| Davis, HW; Schenkman, JB; Suzuki, T | 1 |
| Gohda, H; Narimatsu, S; Watanabe, K; Yamamoto, I; Yoshimura, H | 1 |
| Jenner, P; Mesnil, M; Testa, B | 1 |
| Iba, MM; Lang, B | 1 |
| Stevenson, DK; Vreman, HJ | 1 |
| Kodaira, H; Spector, S | 1 |
| Kishimoto, Y; Shigematsu, H | 1 |
| Diehl, H; Schröder, U | 1 |
| Forkert, PG; Hofley, M; Racz, WJ | 1 |
| Ames, MM; Anderholm, DC; Miller, KJ | 1 |
| Smith, AG; Stewart, FP | 1 |
| Gram, TE; Okine, LK | 1 |
| Chiu, PL; Yang, SK | 1 |
| Bickers, DR; Das, M; Kaufmann, I; Merk, HF; Mukhtar, H | 1 |
| Abraham, NG; Dunn, MW; Masferrer, J; McGiff, JC; Schwartzman, ML | 1 |
| Kuwahara, S; Mannering, GJ | 1 |
| Braun, AG; Harding, FA; Weinreb, SL | 1 |
| Wickramasinghe, SN | 1 |
| Croft, JE; Harrelson, WG; Parandoosh, Z; Philpot, RM | 1 |
| Inoue, T; Kishi, T; Niwaguchi, T; Suzuki, S; Yasuda, T | 1 |
| Doussiere, J; Morel, F; Stasia, MJ; Vignais, PV | 1 |
| Koransky, W; Vohland, HW | 1 |
| Christensen, F | 1 |
| Green, I; Jollow, DJ; Mitchell, JR; Sasame, HA; Thorgeirsson, SS | 1 |
| Menard, RH; Purvis, JL | 1 |
| Chakraborty, J; Hopkins, R; Parke, DV | 1 |
| Juchau, MR; Symms, KG | 1 |
| Lehrmann, C; Rummel, W; Ullrich, V | 1 |
| Harwood, JL; Sodja, A; Stumpf, PK | 1 |
| Murphy, PJ | 1 |
| Hellmer, KH; Tabarelli, S; Uehleke, H | 1 |
| Rösen, P; Stier, A | 1 |
| Helia, O; Jindra, A | 1 |
| Tabarelli, S; Uehleke, H | 1 |
| Short, CR; Stith, RD | 1 |
| Bergheim, P; Netter, KJ; Rathgen, GH | 1 |
| Kadlubar, FF; McKee, EM; Ziegler, DM | 1 |
| Björkhem, I; Gustafsson, J | 1 |
| Bolt, HM; Kappus, H; Remmer, H | 2 |
| Mazel, P; Shargel, L | 2 |
| Boyd, GS; Grimwade, AM; Lawson, ME | 1 |
| Brodie, BB; Davis, DC; Gillette, JR; Jollow, DJ; Mitchell, JR; Potter, WZ | 1 |
| Coscia, CJ; Meehan, TD | 1 |
| Hellmer, KH; Tabarelli-Poplawski, S; Uehleke, H | 1 |
| Fujita, T; Mannering, GJ | 1 |
| Rane, A | 1 |
| Hsia, SL; Prager, GN; Voigt, W | 1 |
| Ishidate, K; Kawaguchi, K; Tagawa, K | 1 |
| Gonasun, LM; Kocsis, JJ; Snyder, R; Witmer, C | 1 |
| Gibbons, GF; Mitropoulos, KA | 1 |
| Jellinck, PH; Smith, G | 1 |
| Hoshita, N; Okuda, K; Taniguchi, S | 1 |
| Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; McCay, PB; Poyer, JL | 1 |
| Davis, PS; Kamin, H; Siegel, LM | 1 |
| Kamin, H; Murphy, MJ; Siegel, LM | 1 |
| Hrycay, EG; O'Brien, PJ | 1 |
| DeLuca, HF; Ghazarian, JG | 1 |
| Boose, R; May, HE; Reed, DJ | 1 |
| Kamataki, T; Kitagawa, H | 2 |
| Stawarz, RJ; Stitzel, RE | 1 |
| Neal, RA; Norman, BJ; Poore, RE | 1 |
| Ichihara, K; Kusunose, E; Kusunose, M | 4 |
| Bidlack, WR; Hochstein, P | 1 |
| Fuchs, G; Käufer, B; Schnitker, U; Thauer, RK | 1 |
| Davis, TK; Sloane, NH | 1 |
| Conn, EE; Potts, JR; Rowell, J; Weklych, R | 1 |
| Björkhem, I; Danielsson, H | 2 |
| Coon, MJ; van der Hoeven, TA | 1 |
| Kamataki, T; Kitada, M; Kitagawa, H | 1 |
| Estabrook, RW; Hrycay, EG | 1 |
| Douch, PG | 1 |
| Hasumura, Y; Lieber, CS; Teschke, R | 1 |
| Ball, EG | 1 |
| Hershberger, WK; Juchau, MR; Pedersen, MG | 1 |
| Kikuchi, G; Yoshida, T | 1 |
| Matschiner, JT; Willingham, AK | 1 |
| Boulton, CA; Crabbe, MJ; Large, PJ | 1 |
| Ericsson, JL; Ernster, L; Orrenius, S | 1 |
| Cram, RL; Fouts, JR; Juchau, MR | 1 |
| Cooper, DY; Narasimhulu, S; Rosenthal, O | 1 |
| Fouts, JR; Juchau, MR; Mullen, JO | 1 |
| Horie, S; Kinoshita, T; Shimazono, N; Yohro, T | 1 |
| Neal, RA | 1 |
| Estabrook, RW; Remmer, H; Schenkman, JB | 1 |
| Hagihara, B; Ichikawa, Y; Yamano, T | 1 |
| Gillette, JR; Hernandez, PH; Mazel, P | 1 |
| Eberhardt, U | 1 |
| Coon, MJ; Lu, AY | 1 |
| Hsia, SL; Thomas, PJ; Voigt, W | 1 |
| Das, ML; Ernster, L; Orrenius, S | 1 |
| Einarsson, K | 1 |
| Harding, BW; Oldham, SB; Wilson, LD | 1 |
| Juchau, MR; Krasner, J; Yaffe, SJ | 2 |
| Gage, JC | 1 |
| Gaylor, JL; Mason, HS; Miyake, Y | 1 |
| Gelboin, HV; Nebert, DW | 1 |
| Goto, M; Sakamoto, Y; Shibata, H; Wada, F | 1 |
| Fujishima, H; Ichikawa, Y; Yamano, T | 1 |
| Chen, C; Lin, CC | 1 |
| Gerhards, E | 1 |
| Hecker, E; Marks, F | 1 |
| Akov, S; Borkovec, AB; Oliver, JE | 1 |
| Gigon, PL; Gillette, JR; Gram, TE | 1 |
| Gillette, JR; Sasame, HA | 1 |
| Coon, MJ; Junk, KW; Lu, AY | 1 |
| Nicholas, DJ; Prabhakararao, K | 1 |
| Ichiha, K; Kushunose, E; Kusunose, M | 1 |
| Creaven, PJ; Reese, WN; Roach, MK | 1 |
| Murphy, PJ; West, CA | 1 |
| Gillette, JR | 2 |
| Lisboa, BP; Orrenius, S; von Bahr, C | 1 |
| Marver, HS; Schmid, R; Tenhunen, R | 1 |
| Walker, CH | 1 |
| Prough, RA; Reed, DJ; Wittkop, JA | 1 |
| Kumaoka, H; Yoshida, Y | 1 |
| Nebert, DW | 1 |
| Ichikawa, Y; Yamano, T | 1 |
| Heinz, E; Spencer, JF; Tulloch, AP | 1 |
| Holtzman, JL | 1 |
| Whereat, AF | 1 |
| Coon, MJ; Heidema, J; Lu, AY; Strobel, HW | 1 |
| Hendler, RW; Nanninga, N | 1 |
| Becker, GE; Nason, A; O'Kelley, JC | 1 |
| Cronholm, T; Johansson, G | 1 |
| Lange, G; Thun, KJ | 1 |
| Diehl, H; Schädelin, J; Ullrich, V | 1 |
| Hellmer, KH; Schnitger, F; Uehleke, H | 1 |
| Folsom, MD; Hodgson, E | 2 |
| Russell, DW | 1 |
| Estabrook, RW; Franklin, MR | 1 |
| Jakobsson, S; Orrenius, S; Thor, H | 1 |
| Schechter, MS; Williamson, RL | 1 |
| Berezney, R; Crane, FL | 1 |
| Johansson, G | 1 |
| Boyd, GS; Mason, JI | 1 |
| Alvares, AP; Kuntzman, R; Levin, W; Schilling, G | 1 |
| Bryan, GT; Lewis, AM | 1 |
| Carter, EA; Isselbacher, KJ | 1 |
| Rikans, LE; Van dyke, RA | 1 |
| Feller, DR; Gillette, JR; Morita, M | 1 |
| Aust, SD; Spike, TE | 1 |
| Alvares, AP; Kappas, A; Mitani, F; Sassa, S | 1 |
| Miyake, Y; Mori, K; Yamano, T | 1 |
| Sawyer, BC; Slater, TF | 1 |
| Garner, JV; Garner, RC; Hanson, RS; Miller, EC; Miller, JA | 1 |
| Estabrook, RW; Franklin, MR; Hildebrandt, AG; Roots, I | 1 |
| Narasimhulu, S | 1 |
| Mattocks, AR; White, IN | 1 |
| Jacobson, M; Kuntzman, R; Levin, W | 1 |
| Bickel, MH | 1 |
| Donahue, JD; Johnson, RK; Jondorf, WR; Mazel, P | 1 |
| Gnosspelius, Y; Orrenius, S; Thor, H | 1 |
| Asakura, T; Chance, B; Oshino, N; Oshino, R; Tamura, M | 1 |
| Ichikawa, Y; Loehr, JS | 1 |
| Eady, RR; Jarman, TR; Large, PJ | 1 |
| Hodgson, E; Philpot, RM | 1 |
| Ellin, A; Jakobsson, SV; Orrenius, S; Schenkman, JB | 1 |
| Cooper, DY; Marver, H; Pimstone, NR; Schmid, R; Tenhunen, R; Trager, WF | 1 |
| Van Dyke, RA; Wineman, CG | 1 |
| Balny, C; Debey, P | 1 |
| Kupfer, D; Levin, E | 1 |
| Ley, HG; Scholz, R; Thurman, RG | 1 |
| Cooper, HL; Gelboin, VH; Whitlock, JP | 1 |
| Björkhem, I | 1 |
| Blank, ML; Malone, B; Snyder, F; Wykle, RL | 1 |
| Thauer, RK | 1 |
| Hlavica, P | 1 |
| Fazekas, AG; Lanthier, A; Leblanc, H; Lehoux, JG; Sandor, T | 1 |
| Leblanc, H; Lehoux, JG; Sandor, T | 1 |
| Balasubramaniam, S; Mitropoulos, KA | 1 |
| Athanassopoulos, S; Hellmer, KH; Murray, RE; Reiner, O; Uehleke, H | 1 |
| Cooper, DY; Czygan, P; Greim, H; Hutterer, F; Popper, H; Rosenthal, O; Schaffner, F; Trülzsch, D | 1 |
| Frommer, U; Orrenius, S; Staudinger, H; Ullrich, V | 1 |
| Harrelson, WG; Mason, RP | 1 |
| Morel, F; Vignais, PV | 1 |
| Niven, DF | 1 |
| Castro, JA; de Toranzo, EG; Masana, M | 1 |
| Inano, H; Kojima, I; Ogata, E; Tamaoki, B | 1 |
| Boobis, AR; Davies, DS | 1 |
| George, JW; Pohl, LR | 1 |
| Gévry, G; Navennec, P; Tan, L | 1 |
| Arrabaça, JD; Loureito Dias, MC | 1 |
| Aasen, AJ; Hansen, CE; Pedersen, JI; Støren, O; Størmer, FC | 1 |
| Fishman, J; Norton, B | 1 |
| Oshima, H; Troen, P; Yoshida, KI | 1 |
| Miura, Y | 1 |
| Cross, AR; Harper, AM; Higson, FK; Jones, OT; Segal, AW | 1 |
| Das, M; Dixit, R; Mukhtar, H; Seth, PK | 1 |
| Lamb, RG; Schwertz, DW | 1 |
| Bidlack, WR; Muakkassah, SF; Yang, WC | 1 |
| Feyereisen, R; Hamnett, AF; Pratt, GE | 1 |
| de Groot, H; Haas, W | 1 |
| Lamb, LC; Roberts, AB; Sporn, MB | 1 |
| Hollenberg, PF; Koop, DR | 1 |
| Anders, MW; Wilkinson, CF; Yu, LS | 1 |
| Halpert, J; Neal, RA | 1 |
| Bellward, GD; Finlayson, MJ | 1 |
| Ahr, HJ; King, LJ; Nastainczyk, W; Ullrich, V | 1 |
| Fukuto, JM; Griscavage, JM; Ignarro, LJ; Komori, Y | 1 |
| Alvarez, AI; Del Estal, JL; Prieto, JG; Redondo, P; Villaverde, C; Voces, J | 1 |
| Smith, TJ; Stoner, GD; Yang, CS | 1 |
| Fukushima, K; Hirose, T; Ogawa, N; Satoh, T; Suwa, T | 1 |
| Brien, JF; Cook, MN; Marks, GS; McLaughlin, BE; Nakatsu, K; Stevenson, DK; Vreman, HJ | 1 |
| Murphy, SE; Spina, DA | 1 |
| Ahmed, F; Kelly, SL; Smith, KE; Williams, RA | 1 |
| Beaune, PH; Bourdi, M; Pessayre, D; Tinel, M | 1 |
| Durst, F; Kazmaier, M; Pompon, D; Regnier, S; Teutsch, HG; Urban, P; Werck-Reichhart, D | 1 |
| Myers, CR; Pratt, PF | 1 |
| Kitada, M; Kitagawa, H; Misaizu, T; Nakamura, T; Ohmori, S; Takano, N | 1 |
| Akhtar, MH; Mahadevan, S; Russell, F | 1 |
| Huang, YS; Sultatos, LG | 1 |
| Du, L; Halkier, BA; Lykkesfeldt, J; Olsen, CE | 1 |
| Amore, BM; Bennett, GD; Finnell, RH; Kalhorn, TF; Lillibridge, JH; Nelson, SD; Slattery, JT | 1 |
| Bates, JN; Holmes, RW; Snyder, GD; Van Voorhis, BJ | 1 |
| Feyereisen, R; Murataliev, MB | 1 |
| Kotze, AC | 1 |
| Albores, A; Eldirdiri, NI; Ferrara, R; King, LJ; Manno, M; Tolando, R | 1 |
| Kitamura, S; Tatsumi, K | 1 |
| Bondoc, FY; Hong, JY; Huang, WQ; Lee, M; Wang, YY; Yang, CS | 1 |
| Castro, JA; de Toranzo, EG; Herrera, DM | 1 |
| Brandes, LJ; LaBella, FS; Queen, GM | 1 |
| Marletta, MA; Rusche, KM; Spiering, MM | 1 |
| Rueffer, M; Zenk, MH | 1 |
| Gross, SS; Ikeda-Saito, M; Liu, Q; Martásek, P; Masters, BS; Migita, CT; Miller, RT; Raman, CS; Roman, LJ; Salerno, JC | 1 |
| Liu, H; Mount, DB; Nasjletti, A; Wang, W | 1 |
| el-Alfy, A; Perkins, EJ; Schlenk, D | 1 |
| Kelly, SL; Lamb, DC; Maspahy, S | 1 |
| Inoue, K; Katano, N; Ooi, A; Yamamoto, H | 1 |
| Kitamura, S; Ohta, S; Sugihara, K; Tatsumi, K | 1 |
| Brien, JF; Graham, CH; Hutchinson, JM; Marks, GS; McLaughlin, BE; Nakatsu, K; Smith, GN | 1 |
| Dunham, WR; Hollenberg, PF; Kent, UM; Moon, N; Roberts-Kirchhoff, ES | 1 |
| Iio, R; Inoue, K; Katano, N; Yamamoto, H | 1 |
| Inoue, K; Yamamoto, H; Yatou, A | 1 |
| Alcón, S; Camello, PJ; Miller, SM; Morales, S; Pozo, MJ; Salido, GM | 1 |
| Ruppert, M; Stöckigt, J; Yu, B | 1 |
| Dioum, EM; Gilles-Gonzalez, MA; Gonzalez, G; McKnight, SL; Rutter, J; Tuckerman, JR | 1 |
| Rutter, J | 1 |
| Alworth, WL; Blobaum, AL; Hollenberg, PF; Kent, UM | 1 |
| Boehning, D; Snyder, SH | 1 |
| Hori, M; Inoue, K; Kuwajima, H; Yamamoto, H | 1 |
| Ikezawa, N; Inouye, K; Nagayoshi, M; Sakaki, T; Sato, F; Shinkyo, R; Tanaka, M | 1 |
| Tschirret-Guth, RA; Wood, HB | 1 |
| Compagnon, V; Crouch, NP; De Luca, V; Rodriguez, S; St-Pierre, B | 1 |
| HACKETT, DP; KLAPPER, MH | 1 |
| BIDE, RW; COLLIER, HB | 1 |
| KAMIN, H; MODIRZADEH, J | 1 |
| Chang, SC; Hwang, B; Kim, SK; Kim, TW; Lee, JS; Takatsuto, S; Yokota, T | 1 |
| Baillie, TA; Kumar, S; Mitra, K; Stearns, RA; Yin, W | 1 |
| Chapman, SK; Cheesman, MR; Fulco, AJ; Gustafsson, MC; Marshall, KR; Munro, AW; Noble, MA; Pessegueiro, A; Roitel, O; von Wachenfeldt, C | 1 |
| Bacci, ML; Bach, FH; Bracco, A; Calise, F; Cozzi, E; D'Alise, G; Di Florio, E; Forni, M; Froio, A; Giovannoni, R; Lavitrano, M; Maccherini, M; Mancini, A; Musumeci, A; Otterbein, LE; Patti, M; Simeone, F; Slominska, E; Smolenski, RT; Stassi, G; Yacoub, MH | 1 |
| Bould, J; Iles, DE; Kemp, PJ; Mason, HS; Peers, C; Riccardi, D; Williams, SE; Wootton, P | 1 |
| Hoshi, T; Lahiri, S | 1 |
| Boundy, S; Dash, HA; ffrench-Constant, RH; Halliwell, CM; Jenkins, AT | 1 |
| Helsby, NA; Tang, MH; Tingle, MD; Wilson, WR | 1 |
| Brown, KM; Murphy, SE; von Weymarn, LB | 1 |
| Boer, R; Hesslinger, C; Kenney, CT; Strub, A; Stuehr, DJ; Tiso, M | 1 |
| Buldain, G; de Montellano, PO; Evans, JP; Niemevz, F | 1 |
| Stevenson, DK; Vreman, HJ; Wong, RJ | 1 |
| Qu, HY; Shang, ZL; Tao, ST; Wu, HQ; Wu, J; Wu, JY; Xu, GH; Zhang, SL | 1 |
| Krishnan, S; Rusling, JF; Schenkman, JB; Wasalathanthri, D; Zhao, L | 1 |
| Amunugama, HT; Hollenberg, PF; Zhang, H | 1 |
| Huang, H; Kahnt, J; Köpke, M; Mueller, AP; Thauer, RK; Wang, S | 1 |
| Gerth, ML; Köpke, M; Liew, F; Maddock, DJ; Mueller, AP; Patrick, WM; Simpson, SD | 1 |
| Chen, Y; Cho, GJ; Choi, HS; Chung, HT; Joe, Y; Kim, HJ; Kim, UH; Park, J; Park, JW; Rah, SY; Ryter, SW; Ryu, J | 1 |
4 review(s) available for carbon monoxide and nadp
| Article | Year |
|---|---|
The oxygen sensing characteristics of microsomal enzymes.
Topics: Animals; Carbon Monoxide; Coenzyme A; Cytochrome P-450 Enzyme System; Electron Transport; Enzyme Induction; Ethylmorphine-N-Demethylase; Flavoproteins; Hydrogen Peroxide; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen; Oxygen Consumption; Peroxidases; Phenobarbital; Superoxides | 1977 |
Fatty acid hydroxylation in rat kidney cortex microsomes.
Topics: Animals; Binding Sites; Carbon Monoxide; Catalase; Chromatography, Gas; Cytochrome P-450 Enzyme System; Fatty Acids; Hemoglobins; Kidney Cortex; Kinetics; Lauric Acids; Male; Microsomes; Mixed Function Oxygenases; NAD; NADP; Protein Binding; Rats; Spectrophotometry; Starvation; Structure-Activity Relationship | 1975 |
Hydroxylations in biosynthesis and metabolism of bile acids.
Topics: Acetates; Animals; Bile Acids and Salts; Biliary Tract Diseases; Carbon Monoxide; Carbon Radioisotopes; Chenodeoxycholic Acid; Cholesterol; Cholic Acids; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport; Enzyme Activation; Hydroxylation; Hyperthyroidism; Liver; Magnesium; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; NADP; Phenobarbital; Phospholipids; Rats; Taurocholic Acid; Thyroid Hormones; Tritium | 1974 |
Factors affecting drug metabolism.
Topics: Adrenalectomy; Age Factors; Animals; Carbon Monoxide; Carbon Tetrachloride; Circadian Rhythm; Cytochromes; Dealkylation; Deamination; Enzyme Induction; Female; Half-Life; Humans; Hydrocortisone; Kinetics; Liver Circulation; Male; Mathematics; Metabolism; Mice; Microsomes, Liver; Mitochondria, Muscle; Mixed Function Oxygenases; Models, Biological; Morphinans; Myocardium; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen; Pharmaceutical Preparations; Protein Binding; Rats | 1971 |
339 other study(ies) available for carbon monoxide and nadp
| Article | Year |
|---|---|
Evaluation of redox state of isolated perfused rat lung.
Topics: Amobarbital; Animals; Antimycin A; Carbon Monoxide; Cyanides; Deoxyglucose; Dihydroxyacetone Phosphate; Fluorescence; Glutamates; Glycerophosphates; In Vitro Techniques; Ketoglutaric Acids; Lactates; Lung; Mitochondria; NAD; NADP; Nitrogen; Oxidation-Reduction; Pentachlorophenol; Pyruvates; Rats | 1976 |
Variation in aryl hydrocarbon (benzo(a)pyrene) hydroxylase activity in heteroploid and predominantly diploid rat liver cells in culture.
Topics: Benz(a)Anthracenes; Benzopyrene Hydroxylase; Carbon Monoxide; Clone Cells; Cycloheximide; Diploidy; Enzyme Induction; Hot Temperature; Kinetics; Mixed Function Oxygenases; NADP; Ploidies; Protein Biosynthesis; Trypsin | 1976 |
Evidence for the involvement of cytochrome P-450 in reduction of benzo(a)pyrene 4,5-oxide by rat liver microsomes.
Topics: Aging; Animals; Benzopyrenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Female; Kinetics; Liver; Male; Microsomes, Liver; NADP; Oxides; Phenobarbital; Rats; Sex Factors | 1976 |
Further studies on the properties of human placental microsomal cytochrome P-450.
Topics: Ascorbic Acid; Carbon Monoxide; Cytochrome P-450 Enzyme System; Female; Glutathione; Humans; In Vitro Techniques; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Placenta; Pregnancy; Steroids; Succinates | 1976 |
Interactions of various 19-nor steroids with human placental microsomal cytochrome P-450 (P-450hpm).
Topics: Androstenedione; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Female; Humans; Kinetics; Microsomes; NADP; Norsteroids; Placenta; Pregnancy; Protein Binding; Testosterone | 1976 |
The carbon monoxide-binding hemoprotein reducible by hydrogen peroxide in microsomal fractions of pea seeds.
Topics: Carbon Monoxide; Cytochrome P-450 Enzyme System; Dithionite; Hemeproteins; Hydrogen Peroxide; Microsomes; NAD; NADP; Oxidation-Reduction; Protein Binding; Seeds; Spectrophotometry; Subcellular Fractions | 1977 |
Reduction of tertiary amine N-oxides by rat liver mitochondria.
Topics: Adenosine Triphosphate; Amines; Aniline Compounds; Animals; Antimycin A; Benzothiazoles; Carbon Monoxide; Citric Acid Cycle; Cyanides; Dicarboxylic Acids; Digitonin; Imipramine; In Vitro Techniques; Male; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Phenobarbital; Piperazines; Rats; Rotenone; Thiazoles; Tricarboxylic Acids | 1977 |
Hydroxylation of dehydroepiandrosterone in the eye lens.
Topics: Animals; Carbon Monoxide; Cattle; Cell Membrane; Cytosol; Dehydroepiandrosterone; Epithelium; Hydroxylation; Lens, Crystalline; NADP; Steroid Hydroxylases | 1977 |
The interaction of vinyl chloride with rat hepatic microsomal cytochrome P-450 in vitro.
Topics: Animals; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Protein Binding; Rats; Spectrophotometry; Vinyl Chloride; Vinyl Compounds | 1977 |
On the aromatic hydroxylation of amphetamine in rat liver microsomes and perfused liver preparations: effects of long-term administration.
Topics: Administration, Oral; Amphetamines; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Desipramine; Fenfluramine; Hydroxylation; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Perfusion; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Time Factors | 1977 |
Formaldehyde formation as a metabolite of methoxyflurane.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Formaldehyde; Haplorhini; Male; Methoxyflurane; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Rabbits; Rats | 1977 |
Bioactivation of carbon tetrachloride, chloroform and bromotrichloromethane: role of cytochrome P-450.
Topics: Allylisopropylacetamide; Animals; Bromotrichloromethane; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Glutathione; Immune Sera; In Vitro Techniques; Male; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Nitrogen; Proadifen; Protein Binding; Rats | 1977 |
Characteristics of a cytochrome P-450-dependent fatty acid omega-2 hydroxylase from bacillus megaterium.
Topics: Bacillus megaterium; Carbon Monoxide; Cytochrome P-450 Enzyme System; Kinetics; Mixed Function Oxygenases; NADP; Palmitic Acids; Protein Binding; Spectrophotometry | 1977 |
The reduction of polyhalogenated methanes by liver microsomal cytochrome P450.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Enzyme Induction; Hydrocarbons, Halogenated; In Vitro Techniques; Light; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Phenobarbital; Rats; Spectrophotometry; Spectrophotometry, Infrared; Time Factors | 1977 |
A new method for determination of microsomal haem oxygenase (EC 1.14.99.3) based on quantitation of carbon monoxide formation.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Heme; In Vitro Techniques; Methemalbumin; Methods; Microsomes; Mixed Function Oxygenases; NADP; Rats | 1978 |
Metabolism of naphthalene by cell extracts of Cunninghamella elegans.
Topics: Carbon Monoxide; Cytochrome P-450 Enzyme System; Enzyme Induction; Fungi; Microsomes; Mucorales; NADP; Naphthalenes; Oxygenases; Subcellular Fractions | 1978 |
Corticotropin-induced changes in a soluble desmolase preparation.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Caproates; Carbon Monoxide; Cholesterol; Cholesterol Side-Chain Cleavage Enzyme; Cycloheximide; Cytosol; Male; Mitochondria; NADP; Oxidoreductases; Pregnenolone; Rats | 1978 |
Ecdysterone biosynthesis: a microsomal cytochrome-P-450-linked ecdysone 20-monooxygenase from tissues of the African migratory locust.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ecdysone; Ecdysterone; Grasshoppers; Malpighian Tubules; Microsomes; NADP; NADPH-Ferrihemoprotein Reductase; Oxygen; Steroid Hydroxylases; Tissue Distribution | 1978 |
Kinetics of liver microsomal cholecalciferol 25-hydroxylase in vitamin D-depleted and -repleated rats.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Cholecalciferol; Kinetics; Male; Microsomes, Liver; NADP; Rats; Steroid Hydroxylases; Surface-Active Agents; Vitamin D Deficiency | 1978 |
Destruction of heme and hemoproteins mediated by liver microsomal reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Heme; Hemeproteins; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Spectrophotometry | 1978 |
Characterization of cytochrome P-450-dependent aminopyrine N-demethylase in rat brain: comparison with hepatic aminopyrine N-demethylation.
Topics: Aminopyrine N-Demethylase; Androstenedione; Aniline Compounds; Animals; Benzopyrenes; Brain; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hexobarbital; In Vitro Techniques; Kinetics; Male; Meperidine; Microsomes; Microsomes, Liver; NAD; NADP; Proadifen; Proteins; Rats | 1979 |
ACTH-stimulated rabbit adrenal 17alpha-hydroxylase. Kinetic properties and a comparison with those of 3beta-hydroxysteroid dehydrogenase.
Topics: 17-alpha-Hydroxypregnenolone; 3-Hydroxysteroid Dehydrogenases; Adrenal Glands; Adrenocorticotropic Hormone; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Kinetics; Male; Microsomes; NADP; Pregnenolone; Rabbits; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases | 1978 |
Acidic steroid metabolites: biosynthesis of steroid carboxylic acids by rabbit liver microsomes and the involvement of a cytochrome P450-independent mixed function oxidase system.
Topics: Androstenes; Animals; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Desoxycorticosterone; Female; Hydrogen-Ion Concentration; Microsomes, Liver; Mitochondria, Liver; Mixed Function Oxygenases; NAD; NADP; Nitrogen; Oxidoreductases; Phenobarbital; Progesterone; Rabbits | 1978 |
Studies on the delta 5-desaturation in ergosterol biosynthesis in yeast.
Topics: Ascorbic Acid; Carbon Monoxide; Cyanides; Cytochrome c Group; Ergosterol; Glucose Oxidase; Guanosine Diphosphate; Mixed Function Oxygenases; NADP; Oxygen; Saccharomyces cerevisiae; Subcellular Fractions; Vitamin K | 1979 |
[Cytochrome P-450 catalyzed oxidation of 1-piperidinoanthraquinone].
Topics: Animals; Anthraquinones; Carbon Monoxide; Catalysis; Cytochrome P-450 Enzyme System; Deoxycholic Acid; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Phenobarbital; Piperidines; Rats; Spectrum Analysis | 1979 |
An NADPH-induced change in lipid bilayer of rat liver microsomes as observed by spin-labeled phosphatidylcholine.
Topics: Animals; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Intracellular Membranes; Microsomes, Liver; NADP; Nitriles; Oxidation-Reduction; Phosphatidylcholines; Rats; Spin Labels | 1979 |
Hydroxylation of dehydroepiandrosterone in human scalp hair follicles.
Topics: Androstenediols; Autoradiography; Carbon Monoxide; Dehydroepiandrosterone; Hair; Humans; Hydroxylation; Metyrapone; Mixed Function Oxygenases; NADP; Scalp; Subcellular Fractions | 1979 |
Microsomal metabolism of arylamides by the rat and guinea pig--II. Oxidation of 3-fluorenylacetamide at carbon atom 9. Formation of 3-acetamido-9-fluorenone.
Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Carbon Monoxide; Fluorenes; Guinea Pigs; Hydrogen-Ion Concentration; Hydroxylation; In Vitro Techniques; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Rats | 1979 |
2-Acetylaminofluorene metabolism in rat liver microsomes: formation of 9-hydroxy-2-acetylaminofluorene and effect of hepatic enzyme modifiers.
Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Carbon Monoxide; Hydroxylation; In Vitro Techniques; Liver; Male; Metyrapone; Microsomes, Liver; NADP; Rats | 1979 |
The apparent loss of cytochrome P-450 associated with metabolic activation of carbon tetrachloride.
Topics: Animals; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; In Vitro Techniques; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Viologens | 1979 |
Biodegradation of alpha-hexachlorocyclohexane. VI. The cechlorination of alpha-hexachlorocyclohexane by microsomes and cytosol of rat liver.
Topics: Acetone; Animals; Biodegradation, Environmental; Carbon Monoxide; Cytosol; Female; Glutathione; Hexachlorocyclohexane; Liver; Microsomes, Liver; NADP; Proadifen; Rats; Sulfobromophthalein | 1975 |
In vitro metabolic conversion of aflatoxins and benzo(alpha)pyrene to nucleic acid-binding metabolites.
Topics: Aflatoxins; Animals; Benzopyrenes; Carbon Monoxide; Cell Fractionation; DNA; Liver; Methylcholanthrene; Micrococcus; Microsomes, Liver; NADP; Nitrogen; Nucleic Acid Denaturation; Phenobarbital; Proadifen; Rats; RNA; RNA, Transfer; Spectrum Analysis; Thymus Gland; Tritium | 1975 |
Aryl hydrocarbon (benzo[a]pyrene) hydroxylase: a mixed-function oxygenase in mouse skin.
Topics: Animals; Anthracenes; Benzopyrenes; Carbon Monoxide; Enzyme Induction; Flavonoids; Injections, Intraperitoneal; Kinetics; Liver; Lung; Methylcholanthrene; Mice; Mixed Function Oxygenases; NADP; Naphthacenes; Phenanthrenes; Skin | 1975 |
The biosynthesis of plasmalogens by rat brain: involvement of the microsomal electron transport system.
Topics: Animals; Ascorbic Acid; Brain; Carbon Monoxide; Chromatography, Thin Layer; Cyanides; Electron Transport; Microsomes; NAD; NADP; Oxygen; Partial Pressure; Phospholipids; Plasmalogens; Rats; Time Factors | 1975 |
Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. VIII. Different catalytic activities of rabbit and rat cytochromes P-448.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Cytochrome Reductases; Cytochromes; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Pharmaceutical Preparations; Proadifen; Rabbits; Rats | 1975 |
In vitro hepatic and extra-hepatic reduction of (minus)-nicotine-1'-N-oxide in rats.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Chromatography, Gas; Cyclic N-Oxides; Cytochrome P-450 Enzyme System; Digestive System; Duodenum; Edetic Acid; Flavins; Gastric Mucosa; Ileum; In Vitro Techniques; Intestines; Kidney; Kinetics; Liver; Lung; Male; Microsomes; Microsomes, Liver; Mitochondria, Liver; Myocardium; NADH, NADPH Oxidoreductases; NADP; Nicotine; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Proadifen; Proteins; Rats | 1975 |
Aflaxation B1 hydroxylation by hepatic microsomal preparations from the rhesus monkey.
Topics: Aflatoxins; Animals; Biotransformation; Carbon Monoxide; Hydrogen-Ion Concentration; Hydroxylation; In Vitro Techniques; Macaca mulatta; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Proadifen; Time Factors | 1975 |
Metabolism of monohydroxybenzo(a)pyrenes by rat liver microsomes and mammalian cells in culture.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Cells, Cultured; Chromatography; Cricetinae; Embryo, Mammalian; Flavonoids; Hydroxylation; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Rats; Spectrometry, Fluorescence; Tritium | 1975 |
Microsomal ethanol oxidation: activity in vitro and in vivo.
Topics: Animals; Azides; Carbon Monoxide; Catalase; Cyanides; Ethanol; Hydrogen Peroxide; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Pyrazoles; Rats | 1975 |
Carbon monoxide and hydroxymercuribenzoate sensitivity of a fatty acid (omega-2) hydroxylase from Bacillus megaterium.
Topics: Bacillus megaterium; Carbon Monoxide; Cysteine; Cytochrome P-450 Enzyme System; Ferredoxins; Glutathione; Hydroxymercuribenzoates; Kinetics; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen; Palmitic Acids | 1975 |
Electron transport systems of lung microsomes and their physiological functions. Enzymic hydroxylation of aniline and steroids.
Topics: Androstadienes; Androstenols; Aniline Compounds; Animals; Carbon Monoxide; Cell-Free System; Chromatography, Thin Layer; Cytochrome c Group; Cytochrome P-450 Enzyme System; Electron Transport; Hydroxylation; Lung; Male; Microsomes; Microsomes, Liver; NADP; NADPH-Ferrihemoprotein Reductase; Oxygen; Phenols; Rabbits; Steroids; Subcellular Fractions; Vitamin K | 1975 |
Drug metabolism in isolated rat liver cells.
Topics: Alprenolol; Animals; Biotransformation; Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Fasting; Glucose; Glucuronates; Imipramine; Lactates; Liver; Methods; Metyrapone; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Protein Binding; Rats; Rotenone; Spectrum Analysis; Temperature; Tritium | 1975 |
The effects of halothane on hepatic microsomal electron transfer.
Topics: Animals; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Electron Transport; Electron Transport Complex IV; Halothane; Male; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Phenobarbital; Rats; Stearoyl-CoA Desaturase | 1975 |
Displacement of carbon monoxide from placental cytochrome P-450 by steroids: antagonistic effects of androstenedione and 19-norandrostenedione.
Topics: Androstenedione; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dithionite; Estrenes; Female; Humans; Kinetics; Microsomes; NADP; Nandrolone; Oxidation-Reduction; Placenta; Pregnancy; Time Factors | 1975 |
Irreversible protein binding of [14-C]imipramine with rat and human liver microsomes.
Topics: Animals; Carbon Monoxide; Cattle; Cytochrome P-450 Enzyme Inhibitors; Epoxide Hydrolases; Humans; Imipramine; In Vitro Techniques; Male; Microsomes, Liver; NADP; Proadifen; Protein Binding; Rats; Rifampin; Serum Albumin, Bovine; Sulfhydryl Compounds; Time Factors | 1975 |
Metabolism of diphenyloxazole (PPO) by mouse liver microsomes.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Carbon Monoxide; Depression, Chemical; Enzyme Induction; Flavonoids; Kinetics; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxazoles; Proadifen | 1975 |
Superoxide-independent reduction of vanadate by rat liver microsomes/NAD(P)H: vanadate reductase activity.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Ferricyanides; Kinetics; Male; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Rats; Rats, Inbred Strains; Superoxide Dismutase; Superoxides; Vanadates | 1992 |
The metabolism of 1,3-dinitrobenzene by rat testicular subcellular fractions.
Topics: Animals; Carbon Monoxide; Chromatography, High Pressure Liquid; Culture Techniques; Dinitrobenzenes; Glutathione; Male; NADP; Nitrobenzenes; Nitroso Compounds; Oxygen; Rats; Rats, Wistar; Testis | 1992 |
Formation of reductive metabolite, 2-sulfamoylacetylphenol, from zonisamide in rat liver microsomes.
Topics: Anaerobiosis; Animals; Anticonvulsants; Carbon Monoxide; Cytochrome P-450 Enzyme System; In Vitro Techniques; Isoxazoles; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenols; Rats; Rats, Inbred Strains; Sulfonamides; Zonisamide | 1992 |
Aromatic hydroxylation of methylenedioxybenzene (MDB) and methylenedioxymethamphetamine (MDMA) by rabbit liver microsomes.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Benzodioxoles; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dioxoles; Hydroxylation; Male; Mass Spectrometry; Microsomes, Liver; Mixed Function Oxygenases; Models, Biological; NADP; Phenols; Potentiometry; Rabbits | 1992 |
Cytochrome P450 catalyzes the oxidation of N omega-hydroxy-L-arginine by NADPH and O2 to nitric oxide and citrulline.
Topics: Animals; Arginine; Carbon Monoxide; Catalysis; Citrulline; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Male; Miconazole; Microsomes, Liver; NADP; Nitric Oxide; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains | 1992 |
Metabolic activation of lidocaine and covalent binding to rat liver microsomal protein.
Topics: Animals; Biotransformation; Carbon Monoxide; Cysteine; Cytochrome P-450 Enzyme System; Debrisoquin; Dose-Response Relationship, Drug; Female; Glutathione; Lidocaine; Male; Microsomes, Liver; NADP; Oxygen; Proadifen; Propranolol; Proteins; Quinidine; Rats; Rats, Inbred Strains | 1992 |
Medicinal azides. Part 8. The in vitro metabolism of p-substituted phenyl azides.
Topics: Aerobiosis; Anaerobiosis; Animals; Azides; Biotransformation; Carbon Monoxide; Chromatography, High Pressure Liquid; In Vitro Techniques; Kinetics; Liver; Mice; Microsomes, Liver; NADP; Oxidation-Reduction | 1991 |
Alkane biosynthesis by decarbonylation of aldehyde catalyzed by a microsomal preparation from Botryococcus braunii.
Topics: Acetates; Acetic Acid; Adenosine Triphosphate; Aldehydes; Alkanes; Carbon Monoxide; Coenzyme A; Dithioerythritol; Eukaryota; Fatty Acids; Microsomes; NADP; Oxidation-Reduction | 1991 |
Microbial transformation of steroids--VII. Hydroxylation of progesterone by extracts of Phycomyces blakesleeanus.
Topics: Carbon Monoxide; Cell Fractionation; Cytochrome P-450 Enzyme System; Dithionite; Hydroxylation; Hydroxyprogesterones; Microsomes; NAD; NADP; Phycomyces; Steroid 11-beta-Hydroxylase | 1991 |
Demethylation of ribosomal RNA by hepatocyte microsomal preparations.
Topics: Animals; Carbon Monoxide; Catalysis; Male; Methylation; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains; RNA, Ribosomal | 1991 |
In vitro generation of carbon monoxide from organic molecules and synthetic metalloporphyrins mediated by light.
Topics: Carbon Monoxide; Heme Oxygenase (Decyclizing); Humans; Light; Metalloporphyrins; NADP; Photic Stimulation; Photochemistry; Protoporphyrins | 1990 |
NADPH-dependent reaction of paraquat in mouse brain microsomes.
Topics: Animals; Brain; Carbon Monoxide; Cells, Cultured; Free Radical Scavengers; Male; Mice; Mice, Inbred ICR; Microsomes; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Nitrogen; Oxidation-Reduction; Paraquat | 1990 |
The in vitro NADPH-dependent inhibition by CCl4 of the ATP-dependent calcium uptake of hepatic microsomes from male rats. Studies on the mechanism of the inactivation of the hepatic microsomal calcium pump by the CCl3.radical.
Topics: Animals; Calcium; Calcium-Transporting ATPases; Carbon Monoxide; Carbon Radioisotopes; Carbon Tetrachloride; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats | 1990 |
Suicide inactivation of cytochrome P-450 by methoxsalen. Evidence for the covalent binding of a reactive intermediate to the protein moiety.
Topics: Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Heme; Kinetics; Methoxsalen; Microsomes, Liver; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Precipitin Tests; Protein Binding; Rats; Rats, Inbred Strains; Spectrum Analysis; Ultraviolet Rays | 1989 |
Chlorogenic acid biosynthesis: characterization of a light-induced microsomal 5-O-(4-coumaroyl)-D-quinate/shikimate 3'-hydroxylase from carrot (Daucus carota L.) cell suspension cultures.
Topics: Carbon Monoxide; Cells, Cultured; Chlorogenic Acid; Cytochrome c Group; Light; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Plants; Stereoisomerism; Substrate Specificity; Triazoles; Vegetables | 1987 |
Prizidilol. Metabolism by cytochrome P-450 and acetyltransferase.
Topics: Acetylation; Acetyltransferases; Adrenergic beta-Antagonists; Animals; Binding Sites; Carbon Monoxide; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Pyridazines; Rats | 1987 |
Kinetic deuterium isotope effects on deamination and N-hydroxylation of cyclohexylamine by rabbit liver microsomes.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Cyclohexylamines; Deamination; Deuterium; Gas Chromatography-Mass Spectrometry; Hydroxylation; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Rabbits | 1989 |
The modulation by arylamines of the in vitro formation of superoxide anion radicals and hydrogen peroxide by rat liver microsomes.
Topics: Amines; Aminobiphenyl Compounds; Animals; Azides; Benzidines; Carbon Monoxide; Carcinogens; Catalase; Cytochrome P-450 Enzyme System; Free Radicals; Hydrogen Peroxide; In Vitro Techniques; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Sodium Azide; Superoxides | 1985 |
Effect of dietary zinc on endogenous free radical production in rat lung microsomes.
Topics: Animals; Body Weight; Carbon Monoxide; Diet; Electron Spin Resonance Spectroscopy; Free Radicals; Lung; Male; Microsomes; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains; Sulfates; Zinc; Zinc Sulfate | 1986 |
Studies on the mechanism of omega-hydroxylation of platelet 12-hydroxyeicosatetraenoic acid (12-HETE) by unstimulated neutrophils.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Benzoflavones; Blood Platelets; Carbon Monoxide; Cytochrome P-450 Enzyme System; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Microsomes; NADP; Neutrophils; Subcellular Fractions | 1987 |
The autotrophic pathway of acetogenic bacteria. Role of CO dehydrogenase disulfide reductase.
Topics: Acetyl Coenzyme A; Amino Acids; Carbon Dioxide; Carbon Monoxide; Clostridium; Coenzyme A; Ferredoxins; Methyltransferases; Molecular Weight; NADP; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Tetrahydrofolates | 1986 |
Oxidation of esterified arachidonate by rat liver microsomes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Esterification; Ferric Compounds; Lipid Peroxides; Male; Malondialdehyde; Microsomes, Liver; NADP; Oxidation-Reduction; Phospholipases A; Phospholipases A2; Phospholipids; Rats; Rats, Inbred Strains | 1987 |
Formation of similar species to carbon monoxide during hepatic microsomal metabolism of cannabidiol on the basis of spectral interaction with cytochrome P-450.
Topics: Animals; Cannabidiol; Cannabinoids; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dithionite; Hydrogen-Ion Concentration; Mice; Microsomes, Liver; NAD; NADP; Oxygen; Spectrum Analysis; Structure-Activity Relationship; Temperature | 1988 |
In vitro inhibition by stiripentol of rat brain cytochrome P-450-mediated naphthalene hydroxylation.
Topics: Animals; Brain; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dioxolanes; Dioxoles; Hydroxylation; Kinetics; Male; Microsomes; NADP; Naphthalenes; Oxidation-Reduction; Rats; Rats, Inbred Strains; Reference Values | 1988 |
Stimulation of the conjugation of lipid dienes in hepatic microsomes by 3,3'-dichlorobenzidine.
Topics: 3,3'-Dichlorobenzidine; Animals; Benzidines; Carbon Monoxide; Cytochrome P-450 Enzyme System; Lipid Metabolism; Lipid Peroxides; Male; Malondialdehyde; Methylcholanthrene; Microsomes, Liver; NADP; Nitrogen; Rats; Rats, Inbred Strains | 1988 |
Heme oxygenase activity as measured by carbon monoxide production.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Female; Heme Oxygenase (Decyclizing); In Vitro Techniques; Liver; Mixed Function Oxygenases; NADP; Rats; Rats, Inbred Strains; Spleen; Temperature | 1988 |
Transformation of thebaine to oripavine, codeine, and morphine by rat liver, kidney, and brain microsomes.
Topics: Animals; Biotransformation; Brain; Carbon Monoxide; Codeine; Kidney; Male; Microsomes; Microsomes, Liver; Morphine; NAD; NADP; Pyridines; Rats; Rats, Inbred Strains; Thebaine | 1988 |
Alpha-hydroxylation of lignoceroyl-CoA by a cyanide-sensitive oxygenase in rat brain microsomes.
Topics: Acyl Coenzyme A; Animals; Brain; Carbon Monoxide; Cyanides; Hydroxylation; Microsomes; NAD; NADP; Oxygen; Oxygenases; Rats; Sphingosine | 1987 |
Substrate specificity of the carbon monoxide-dependent cytochrome P-450 kinetics.
Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Metyrapone; Microsomes, Liver; NADP; Substrate Specificity; Swine | 1987 |
Metabolic activation of 1,1-dichloroethylene by mouse lung and liver microsomes.
Topics: Animals; Biotransformation; Carbon Monoxide; Dichloroethylenes; Hydrocarbons, Chlorinated; Lung; Male; Mice; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Piperonyl Butoxide; Proadifen | 1987 |
Metabolic activation of the serotonergic neurotoxin para-chloroamphetamine to chemically reactive intermediates by hepatic and brain microsomal preparations.
Topics: Amphetamine; Amphetamines; Animals; Biotransformation; Brain; Carbon Monoxide; In Vitro Techniques; Male; Microsomes; Microsomes, Liver; NADP; Oxygen; p-Chloroamphetamine; Protein Binding; Rabbits; Rats; Receptors, Serotonin; Stereoisomerism; Tritium | 1986 |
Metabolism of the "mixed" cytochrome P-450 inducer hexachlorobenzene by rat liver microsomes.
Topics: Acetylcysteine; Aroclors; Carbon Monoxide; Chlorobenzenes; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Ellipticines; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Hexachlorobenzene; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Molecular Weight; NADP; Pentachlorophenol; Phenobarbital; Polychlorinated Dibenzodioxins; Proadifen; Safrole | 1986 |
In vitro studies on the metabolism and covalent binding of [14C]1,1-dichloroethylene by mouse liver, kidney and lung.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dichloroethylenes; Enzyme Induction; Glutathione; Hot Temperature; Hydrocarbons, Chlorinated; In Vitro Techniques; Kidney; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; NADP; Phenobarbital; Piperonyl Butoxide; Pregnenolone Carbonitrile; Proadifen; Subcellular Fractions | 1986 |
Metabolism of 7,8-dihydrobenzo(a)pyrene by rat liver microsomal enzymes and mutagenicity of metabolites.
Topics: Animals; Benzopyrenes; Biotransformation; Carbon Monoxide; Chromatography, High Pressure Liquid; Dihydroxydihydrobenzopyrenes; In Vitro Techniques; Male; Microsomes, Liver; Molecular Conformation; Mutagens; NADP; Rats; Rats, Inbred Strains; Spectrophotometry, Ultraviolet; Stereoisomerism; Trichloroepoxypropane | 1986 |
Human hair follicle benzo[a]pyrene and benzo[a]pyrene 7,8-diol metabolism: effect of exposure to a coal tar-containing shampoo.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Benzoflavones; Carbon Monoxide; Clotrimazole; Coal Tar; Dihydroxydihydrobenzopyrenes; DNA; Drug Interactions; Enzyme Induction; Hair; Hair Preparations; Humans; Ketoconazole; NADP | 1987 |
Cytochrome P450 dependent metabolism of arachidonic acid in bovine corneal epithelium.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Cattle; Chromatography, Thin Layer; Cornea; Cytochrome P-450 Enzyme System; Epithelium; Microsomes; NADP; Proadifen | 1985 |
Evidence for a predominantly NADH-dependent O-dealkylating system in rat hepatic microsomes.
Topics: Animals; Antibodies; Benzoflavones; Carbon Monoxide; Cobalt; Cyanides; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytochromes b5; Dealkylation; Electron Transport; Ethylmorphine; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Male; Manganese; Methylcholanthrene; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Nitrobenzenes; Oxygen; Partial Pressure; Phenobarbital; Proadifen; Rats | 1985 |
Teratogen metabolism: thalidomide activation is mediated by cytochrome P-450.
Topics: Amines; Animals; Biotransformation; Carbon Monoxide; Catalase; Cytochrome P-450 Enzyme System; Dogs; In Vitro Techniques; Isoenzymes; Microsomes, Liver; NADP; Proadifen; Spectrophotometry; Superoxide Dismutase; Thalidomide | 1986 |
Observations on the biochemical basis of ethanol metabolism by human macrophages.
Topics: Amitrole; Carbon Monoxide; Catalase; Cell Survival; Cells, Cultured; Ethanol; Humans; Macrophages; Metyrapone; NADP; Proadifen; Pyrazoles | 1986 |
Unique properties of NADPH- and NADH-dependent metabolism of p-nitroanisole catalyzed by cytochrome P-450 isozyme 2 in pulmonary and hepatic microsomal preparations from rabbits.
Topics: Animals; Anisoles; Carbon Monoxide; Cytochrome b Group; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytochromes b5; Electron Transport; Isoenzymes; Lung; Male; Microsomes; Microsomes, Liver; NAD; NADP; Oxidoreductases, O-Demethylating; Rabbits | 1986 |
The metabolism of 1-phenyl-2-(N-methyl-N-furfurylamino)propane (furfenorex) in the rat in vivo and in vitro.
Topics: Animals; Appetite Depressants; Biotransformation; Carbon Monoxide; Chromatography, Gas; Chromatography, Thin Layer; Furans; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Spectrophotometry | 1986 |
The respiratory burst of bovine neutrophils. Role of a b type cytochrome and coenzyme specificity.
Topics: Animals; Carbon Monoxide; Cattle; Coenzymes; Cytochrome b Group; In Vitro Techniques; Kinetics; NAD; NADH, NADPH Oxidoreductases; NADP; NADPH Oxidases; Neutrophils; Oxygen Consumption; Subcellular Fractions; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 1985 |
Effect of -hexachlorocyclohexane on metabolism and excretion of pentetrazol (cardiazol) in the rat.
Topics: Animals; Anticonvulsants; Brain; Carbon Monoxide; Female; Half-Life; Haplorhini; Hexachlorocyclohexane; Microsomes, Liver; NADP; Oxidoreductases; Oxygen; Pentylenetetrazole; Proadifen | 1972 |
Metabolism of dicoumarol by liver microsomes from untreated and phenobarbital treated rats.
Topics: Animals; Atmosphere; Carbon Monoxide; Chromatography, Paper; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Dicumarol; Male; Microsomes, Liver; Mitochondria, Liver; NAD; NADP; Phenobarbital; Proteins; Rats; Rats, Inbred Strains; Time Factors | 1972 |
The role of cytochrome P-450 in N-hydroxylation of 2-acetylaminofluorene.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Cricetinae; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Fluorenes; gamma-Globulins; Goats; Hydroxylation; Immune Sera; In Vitro Techniques; Male; Mice; Microsomes, Liver; Morphinans; NADH, NADPH Oxidoreductases; NADP; Rats; Time Factors | 1973 |
Studies of cytochrome P-450 in testis microsomes.
Topics: Animals; Birds; Carbon Isotopes; Carbon Monoxide; Chickens; Cyclic AMP; Cytochrome P-450 Enzyme System; Gonadotropins; In Vitro Techniques; Kinetics; Lipids; Male; Mice; Microsomes; NADP; Oxidation-Reduction; Oxygen Consumption; Peroxides; Progesterone; Rats; Spectrophotometry, Ultraviolet; Steroid Hydroxylases; Sulfites; Testis | 1973 |
Inhibition studies on the aromatization of androst-4-ene-3,17-dione by human placental microsomal preparations.
Topics: 17-Ketosteroids; Androstenedione; Androstenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Estrone; Female; Humans; In Vitro Techniques; Microsomes; NADP; Oxygen Consumption; Placenta; Tritium | 1972 |
Mechanism of aromatic nitro group reduction in the soluble fraction of human placenta.
Topics: Aminobenzoates; Ammonium Sulfate; Carbon Monoxide; Dialysis; Female; Flavin Mononucleotide; Humans; In Vitro Techniques; Methemoglobin; NADP; Nitro Compounds; Nitrobenzenes; Oxidation-Reduction; Oxidoreductases; Oxygen; Placenta; Pregnancy; Proteins; Ultrafiltration | 1972 |
Phenobarbital inducible drug monooxygenase activity in the small intestine of mice.
Topics: Animals; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Dealkylation; Enzyme Activation; Enzyme Induction; Female; Fluorescence; Indophenol; Jejunum; Light; Liver; Mice; Microsomes; Monoamine Oxidase; NADP; Oxidoreductases; Phenobarbital; Stimulation, Chemical | 1973 |
Fat metabolism in higher plants. Beta-hydroxylation of fatty acids by a soluble preparation from maturing avocado mesocarp.
Topics: Adenosine Triphosphate; Amides; Carbon Isotopes; Carbon Monoxide; Carboxylic Acids; Chromatography, Gas; Chromatography, Thin Layer; Coenzyme A; Depression, Chemical; Fatty Acids; Fruit; Hydroxylation; Iodoacetates; Metals; NAD; NADP; Oxygen; Plant Extracts; Plants | 1972 |
Enzymatic oxidation of nicotine to nicotine 1'(5') iminium ion. A newly discovered intermediate in the metabolism of nicotine.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Cyanides; Imines; Liver; Mass Spectrometry; Microsomes, Liver; NAD; NADP; Nicotine; Nitriles; Oxidation-Reduction; Oxygen Isotopes; Rabbits; Spectrophotometry, Infrared | 1973 |
Binding of 14 C-carbon tetrachloride to microsomal proteins in vitro and formation of CHC1 3 by reduced liver microsomes.
Topics: Anaerobiosis; Animals; Carbon Isotopes; Carbon Monoxide; Carbon Tetrachloride; Chlorofluorocarbons, Methane; Chloroform; Cystamine; Cytochrome P-450 Enzyme System; Edetic Acid; Ethylmaleimide; Gallic Acid; Glutathione; In Vitro Techniques; Kinetics; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Protein Binding; Proteins; Rabbits; Spectrophotometry | 1973 |
Kinetics of CO and O 2 complexes of rabbit liver microsomal cytochrome P 450 .
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hexobarbital; In Vitro Techniques; Kinetics; Microsomes, Liver; NADP; Oxygen Consumption; Phenobarbital; Photolysis; Protein Binding; Rabbits; Time Factors | 1973 |
The dearalkylation of fomocaine isomers by microsomal monooxygenase system of rabbit liver.
Topics: Adenosine Triphosphate; Anaerobiosis; Anesthetics, Local; Biotransformation; Buffers; Carbon Monoxide; Ethers; Glucosephosphate Dehydrogenase; Hydrogen-Ion Concentration; Microsomes, Liver; Morpholines; NADP; Toluene | 1973 |
N-hydroxylation of 4,4'-diaminodiphenylsulphone (Dapsone) by liver microsomes, and in dogs and humans.
Topics: Animals; Carbon Monoxide; Dapsone; Dogs; Erythrocytes; Female; Hemoglobins; Humans; Hydrogen-Ion Concentration; Hydroxylation; Male; Methemoglobin; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Phenobarbital; Proteins; Rabbits; Time Factors | 1973 |
Perinatal development of hepatic microsomal mixed function oxidase activity in swine.
Topics: Age Factors; Animals; Animals, Newborn; Carbon Monoxide; Cyanides; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Methyltransferases; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Spectrophotometry; Swine | 1973 |
Interaction of drugs and steroids with human placental microsomes.
Topics: Acetanilides; Amphetamine; Anaerobiosis; Androgens; Aniline Compounds; Anisoles; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport; Female; Glucosephosphate Dehydrogenase; Humans; Kinetics; Methyltransferases; Metyrapone; Microsomes; Mixed Function Oxygenases; Myocardium; NADP; Oxidation-Reduction; Oxidoreductases; Pharmaceutical Preparations; Placenta; Pregnancy; Pregnenolone; Progesterone | 1973 |
Reduced pyridine nucleotide-dependent N-hydroxy amine oxidase and reductase activities of hepatic microsomes.
Topics: Aniline Compounds; Animals; Benzyl Compounds; Carbon Monoxide; Hydrogen-Ion Concentration; Hydroxylamines; Kidney; Kinetics; Liver; Lung; Mass Spectrometry; Microsomes, Liver; NAD; NADP; Organ Specificity; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Spectrophotometry; Spectrophotometry, Ultraviolet; Spleen; Subcellular Fractions; Swine | 1973 |
Omega-hydroxylation of steriod side-chain in biosynthesis of bile acids.
Topics: Animals; Bile Acids and Salts; Carbon Monoxide; Chenodeoxycholic Acid; Cholestanes; Cholestenes; Cholesterol; Hydroxylation; Male; Microsomes, Liver; Mitochondria, Liver; NAD; NADP; Phenobarbital; Rats; Starvation; Steroid Hydroxylases | 1973 |
Irreversible protein binding of metabolites of ethynylestradiol in vivo and in vitro.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Charcoal; Chromatography, Gel; Chromatography, Ion Exchange; Endoplasmic Reticulum; Estradiol; Ethinyl Estradiol; Female; Hydroxylation; Male; Microsomes, Liver; NADP; Peptide Fragments; Phenobarbital; Proadifen; Protein Binding; Proteins; Rats; Serum Albumin, Bovine; Time Factors; Tritium; Trypsin | 1973 |
Effect of riboflavin deficiency on phenobarbital and 3-methylcholanthrene induction of microsomal drug-metabolizing enzymes of the rat.
Topics: Aminopyrine N-Demethylase; Animals; Azo Compounds; Benzopyrenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Diet; Enzyme Induction; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitrogen; Oxidoreductases; Phenobarbital; Rats; Riboflavin Deficiency | 1973 |
Studies on rat-liver microsomal cholesterol 7alpha-hydroxylase.
Topics: Animals; Bile Acids and Salts; Carbon Monoxide; Chloromercuribenzoates; Cholesterol; Cholestyramine Resin; Cyanides; Cytochrome c Group; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Rats; Steroid Hydroxylases | 1973 |
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cobalt; Cyanides; Cytochrome P-450 Enzyme System; Fluorenes; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Time Factors; Tritium | 1973 |
Hydroxylation of geraniol and nerol by a monooxygenase from Vinca rosea.
Topics: Alcohols; Azides; Carbon Monoxide; Chromatography, Thin Layer; Cyanides; Hydroxylation; Microsomes; NADP; Oxidoreductases; Plant Cells; Plants; Proadifen; Terpenes; Tritium | 1973 |
Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Radioisotopes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Glutathione; Halothane; In Vitro Techniques; Kidney; Lung; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Proadifen; Protein Binding; Rabbits; Spectrophotometry; Sulfites | 1973 |
Electron transport components of hepatic microsomes. Solubilization, resolution, and recombination to reconstitute aniline hydroxylase activity.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Chloromercuribenzoates; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Electron Transport; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Phenobarbital; Rats; Solubility; Structure-Activity Relationship; Vitamin K | 1973 |
N-oxidation of a tertiary amine (N,N-dimethylaniline) by human fetal liver microsomes.
Topics: Aniline Compounds; Animals; Carbon Monoxide; Chromatography, Paper; Dimethylamines; Female; Fetus; Gestational Age; Humans; Kinetics; Liver; Male; Microsomes, Liver; Middle Aged; NADP; Nitrogen Oxides; Oxidation-Reduction; Proadifen; Rats | 1974 |
Stimulation of taurodeoxycholate 7alpha-hydroxylase of rat liver by adenosine 3':5'-monophosphate and saturated fatty acids.
Topics: Animals; Carbon Monoxide; Carbon Radioisotopes; Chromatography; Chromatography, Gas; Chromatography, Paper; Crystallization; Cyclic AMP; Cytochrome P-450 Enzyme System; Cytosol; Deoxycholic Acid; Enzyme Activation; Fatty Acids; Fatty Acids, Unsaturated; Kinetics; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phosphates; Radiation Effects; Radioisotope Dilution Technique; Rats; Subcellular Fractions; Taurine | 1973 |
Non-mitochondrial electron transfer system in anaerobically grown yeast cells.
Topics: Anaerobiosis; Antimycin A; Carbon Monoxide; Chlorine; Cytochrome P-450 Enzyme System; Electron Transport; Ergosterol; Flavoproteins; Indophenol; NADH, NADPH Oxidoreductases; NADP; Oxygen; Oxygen Consumption; Phospholipids; Saccharomyces cerevisiae | 1973 |
Benzene metabolism in mouse liver microsomes.
Topics: Animals; Benzene; Carbon Monoxide; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Kinetics; Male; Mice; Mice, Inbred ICR; Microsomes, Liver; NADP; Oxidoreductases; Phenobarbital; Tritium | 1973 |
The rôle of cytochrome P-450 in cholesterol biosynthesis.
Topics: Adenosine Triphosphate; Animals; Carbon Monoxide; Carbon Radioisotopes; Cholesterol; Cytochrome P-450 Enzyme System; Lanosterol; Light; Male; Microsomes, Liver; NADP; Nitrogen; Oxygen; Phenobarbital; Rats | 1973 |
Metabolism of 2-hydroxy(4-14C)estradiol by rat liver microsomes.
Topics: Animals; Carbon Monoxide; Carbon Radioisotopes; Catalase; Chromatography, Thin Layer; Cyanides; Diamines; Edetic Acid; Estradiol; Estriol; Ethylenes; Ethylmaleimide; Female; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Sex Factors; Spermine; Ultracentrifugation | 1974 |
Enzymatic characteristics of CO-sensitive 26-hydroxylase system for 5beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol in rat-liver mitochondria and its intramitochondrial localization.
Topics: Animals; Binding Sites; Carbon Monoxide; Cholestanes; Citric Acid Cycle; Cyanides; Digitonin; Electron Transport; Enzyme Activation; Hydroxysteroids; Hypotonic Solutions; Kinetics; Membranes; Microsomes, Liver; Mitochondria, Liver; NADP; Rats; Steroid Hydroxylases; Sterols | 1973 |
Lipid peroxidation and the degradation of cytochrome P-450 heme.
Topics: Aminopyrine; Animals; Benzopyrenes; Benzphetamine; Carbon Monoxide; Chromatography, Paper; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Levulinic Acids; Lipid Metabolism; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Pentobarbital; Peroxidases; Phenobarbital; Protein Binding; Rats; Secobarbital; Spectrophotometry; Time Factors; Tritium | 1973 |
Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. 3. The Escherichia coli hemoflavoprotein: catalytic parameters and the sequence of electron flow.
Topics: Carbon Monoxide; Catalysis; Chromatography, Gel; Cyanides; Dihydrolipoamide Dehydrogenase; Electron Transport; Enterobacteriaceae; Escherichia coli; Flavoproteins; Hemeproteins; Hydrogen-Ion Concentration; Hydroxylamines; Kinetics; NAD; NADP; Nitrite Reductases; Oxidation-Reduction; Oxidoreductases; Paraquat; Spectrometry, Fluorescence; Spectrophotometry; Structure-Activity Relationship; Sulfites; Sulfur Radioisotopes | 1974 |
Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. VI. The reaction of carbon monoxide with the Escherichia coli holoenzyme, the hemoprotein, and free siroheme.
Topics: Carbon Monoxide; Enterobacteriaceae; Escherichia coli; Flavoproteins; Heme; Hemeproteins; Iron; Kinetics; Mathematics; NADP; Oscillometry; Oxidation-Reduction; Oxidoreductases; Photolysis; Porphyrins; Spectrophotometry; Structure-Activity Relationship; Sulfites | 1974 |
Studies on the metabolism of ethynylestradiol in vitro and in vivo: the significance of 2-hydroxylation and the formation of polar products.
Topics: Animals; Carbon Monoxide; Chromatography; Chromatography, Thin Layer; Estradiol; Estrone; Ethinyl Estradiol; Glutathione; Hydroxylation; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Rats; Silicon Dioxide; Spectrophotometry, Ultraviolet; Tritium | 1973 |
Microsomal electron transport. II. Reduced nicotinamide adenine dinucleotide--cytochrome b5 reductase and cytochrome P-450 as electron carriers in microsomal NADH-peroxidase activity.
Topics: Adrenal Glands; Animals; Antimetabolites; Carbon Monoxide; Cattle; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport; Hydrogen-Ion Concentration; Kinetics; Male; Microsomes; Microsomes, Liver; NAD; NADP; Organ Specificity; Osmolar Concentration; Peroxidases; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Trypsin | 1974 |
25-Hydroxycholecalciferol-1-hydroxylase: a specific requirement for NADPH and a hemoprotein component in chick kidney mitochondria.
Topics: Animals; Antimetabolites; Carbon Monoxide; Chickens; Chromatography, Ion Exchange; Electron Transport; Hemeproteins; Hydroxycholecalciferols; Isocitrate Dehydrogenase; Isocitrates; Kidney; Kinetics; Magnesium; Malates; Male; Mitochondria; Mitochondrial Swelling; NAD; NADP; Oxidation-Reduction; Steroid Hydroxylases; Succinates; Tritium | 1974 |
Hydroxylation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU) by rat liver microsomes.
Topics: Animals; Antineoplastic Agents; Carbon Monoxide; Chromatography, Ion Exchange; Cyclohexanes; Hydroxylation; Kinetics; Male; Mass Spectrometry; Microsomes, Liver; NADP; Nitrosourea Compounds; Oxidation-Reduction; Oxygen; Phenobarbital; Rats; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
Diphasic binding of carbon monoxide with cytochrome P-450 of rat liver microsomes reduced by NADPH.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats | 1974 |
Factors influencing the microsomal metabolism of 3H-reserpine.
Topics: Animals; Benzoates; Biotransformation; Carbon Monoxide; Cats; Chromatography, Thin Layer; Depression, Chemical; Dogs; Enzyme Induction; Female; Formaldehyde; Guinea Pigs; Hydrogen-Ion Concentration; Hydrolysis; Liver; Male; Methylcholanthrene; Microsomes, Liver; NAD; NADH, NADPH Oxidoreductases; NADP; Phenobarbital; Proadifen; Rats; Reserpine; Stimulation, Chemical; Temperature | 1974 |
Studies of the binding of sulfur released in the mixed-function oxidase-catalyzed metabolism of diethyl p-nitrophenyl phosphorothionate(parathion) to diethyl p-nitrophenyl phosphate (paraoxon).
Topics: Animals; Benzphetamine; Carbon Monoxide; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dealkylation; Esterases; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidoreductases; Paraoxon; Parathion; Phenobarbital; Solvents; Sulfur; Sulfur Radioisotopes | 1974 |
Partial purification of a carbon monoxide-binding hemoprotein reconstitutively active in fatty acid omega-hydroxylation from porcine kidney cortex microsomes.
Topics: Animals; Carbon Monoxide; Chromatography, DEAE-Cellulose; Chromatography, Gel; Fatty Acids; Hemeproteins; Hydroxylation; Kidney Cortex; Microsomes; Molecular Weight; NADP; Protein Binding; Spectrum Analysis; Swine | 1974 |
Hydroperoxide peroxidase activity in liver microsomes.
Topics: Animals; Antimetabolites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Kinetics; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Peroxidases; Rats | 1974 |
Carbon-monoxide oxidation in cell-free extracts of Clostridium pasteurianum.
Topics: Anaerobiosis; Carbon Dioxide; Carbon Monoxide; Catalysis; Cell-Free System; Chromatography, Gas; Clostridium; Cyanides; Electron Transport; Ferredoxins; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Iodides; Kinetics; Light; NAD; NADP; Oxidation-Reduction; Temperature; Vitamin B 12 | 1974 |
Hydroxymethylation of the benzene ring. Microsomal hydroxymethylation of benzo(alpha)pyrene to 6-hydroxymethylbenzo(alpha)pyrene.
Topics: Aminoglutethimide; Animals; Benzopyrenes; Butanones; Carbon Monoxide; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Drug Stability; Female; Imidazoles; Methanol; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Temperature; Time Factors; Transferases; Tritium; Ultrasonics | 1974 |
The 4-hydroxylation of cinnamic acid by sorghum microsomes and the requirement for cytochrome P-450.
Topics: Carbon Monoxide; Carbon Radioisotopes; Cell Membrane; Chromatography, Paper; Cinnamates; Cytochrome P-450 Enzyme System; Kinetics; Light; Mathematics; Microsomes; Mitochondria; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Oxygen Consumption; Plant Cells; Plants; Poaceae; Quinones; Spectrophotometry; Spectrophotometry, Ultraviolet | 1974 |
Preparation and properties of partially purified cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase from rabbit liver microsomes.
Topics: Animals; Binding Sites; Carbon Monoxide; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Detergents; Dithionite; Electrophoresis, Disc; Electrophoresis, Polyacrylamide Gel; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Heme; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; NADP; Oxidation-Reduction; Phospholipids; Polyethylene Glycols; Protein Binding; Rabbits; Solubility; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfides | 1974 |
Effects of lipid peroxidation on the microsomal electron transport system and the rate of drug metabolism in rat liver.
Topics: Animals; Ascorbic Acid; Carbon Monoxide; Cytochrome c Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport; Lipid Metabolism; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Peroxides; Rats | 1974 |
The effect of extra bound cytochrome b-5 on cytochrome P-450-dependent enzyme activities in liver microsomes.
Topics: Anaerobiosis; Animals; Benzphetamine; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Kinetics; Male; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADP; Oxidation-Reduction; Oxidoreductases, N-Demethylating; Peroxidases; Phenobarbital; Rabbits; Spectrophotometry; Spectrophotometry, Ultraviolet; Time Factors; Ultracentrifugation | 1974 |
The metabolism of some thioureidobenzene fungicides in mice and sheep.
Topics: Animals; Benzene Derivatives; Benzimidazoles; Brain; Carbamates; Carbon Monoxide; Chromatography; Chromatography, Thin Layer; Crystallization; Feces; Fungicides, Industrial; Glucuronates; Glucuronidase; Intestinal Mucosa; Kidney; Liver; Male; Mice; NADP; Organ Specificity; Oxidation-Reduction; Phenylthiourea; Proadifen; Sheep; Silicon Dioxide; Species Specificity; Structure-Activity Relationship; Sulfatases; Sulfuric Acids; Thiourea | 1974 |
NADPH-dependent oxidation of methanol, ethanol, propanol and butanol by hepatic microsomes.
Topics: 1-Propanol; Alcohol Oxidoreductases; Aldehydes; Animals; Butanols; Carbon Monoxide; Catalase; Chromatography, Gas; Ethanol; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Male; Methanol; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen Consumption; Rats | 1974 |
The development of our current concepts of biological oxidations.
Topics: Aldehydes; Biochemistry; Carbon Monoxide; Cyanides; Cytochromes; Electron Transport; Erythrocytes; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; History, 20th Century; Liver; Methylene Blue; Muscles; NAD; NADP; Oxidation-Reduction; Oxygen; Porphyrins; Respiration; Succinate Dehydrogenase; Xanthine Oxidase | 1974 |
Metabolism of 3,4-benzpyrene in rainbow trout (Salmo gairdneri).
Topics: Animals; Benzopyrenes; Biotransformation; Carbon Monoxide; Gills; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kinetics; Liver; Methylcholanthrene; Mixed Function Oxygenases; Muscles; Myocardium; NADP; Nitrogen; Proteins; Salmonidae; Temperature; Trout | 1974 |
Sequence of the reaction of heme catabolism catalyzed by the microsomal heme oxygenase system.
Topics: Animals; Carbon Monoxide; Cytochrome Reductases; Heme; Hydrogen-Ion Concentration; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygenases; Protein Binding; Spectrophotometry; Spleen; Swine; Thiosulfates; Time Factors | 1974 |
Changes in phylloquinone epoxidase activity related to prothrombin synthesis and microsomal clotting activity in the rat.
Topics: Animals; Anticoagulants; Blood Coagulation; Carbon Monoxide; Cyanides; Drug Resistance; Edetic Acid; Epoxy Compounds; Female; Flavin-Adenine Dinucleotide; Hypoprothrombinemias; Kinetics; Male; Microsomes, Liver; NAD; NADP; Oxidoreductases; Oxygenases; Proteins; Prothrombin; Rats; Vitamin K; Vitamin K 1; Vitamin K Deficiency; Warfarin | 1974 |
Microbial oxidation of amines. Partial purification of a trimethylamine mono-oxygenase from Pseudomonas aminovorans and its role in growth on trimethylamine.
Topics: Amines; Carbon Monoxide; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cyanides; Hydrogen-Ion Concentration; Methylamines; NADP; Onium Compounds; Oxygenases; Potassium; Proadifen; Pseudomonas; Quaternary Ammonium Compounds; Spectrophotometry; Sulfides; Sulfonium Compounds; Ultrasonics | 1974 |
Phenobarbital-induced synthesis of the microsomal drug-metabolizing enzyme system and its relationship to the proliferation of endoplasmic membranes. A morphological and biochemical study.
Topics: Aminopyrine; Animals; Carbon Monoxide; Codeine; Dactinomycin; Endoplasmic Reticulum; In Vitro Techniques; Liver; Microscopy, Electron; Microsomes; NADP; Nitrosamines; Oxidoreductases; Phenobarbital; Pigments, Biological; Puromycin; Rats; Thyroidectomy; Triiodothyronine | 1965 |
Stimulation by chlordane of hepatic drug metabolism in the squirrel monkey.
Topics: Aminopyrine; Animals; Benzoates; Benzopyrenes; Carbon Monoxide; Chlordan; Haplorhini; Hexobarbital; In Vitro Techniques; Liver; Microsomes; NADP; Oils; Organ Size; Zoxazolamine | 1965 |
Spectrophotometric properties of a Triton-clarified steroid 21-hydroxylase system of adrenocortical microsomes.
Topics: Adrenal Glands; Androgens; Animals; Carbon Monoxide; Cattle; Cytochromes; Hydroxyprogesterones; In Vitro Techniques; Microsomes; Mixed Function Oxygenases; NAD; NADP; Spectrophotometry; Sulfites; Surface-Active Agents | 1965 |
Studies of 3,4-benzpyrene, 3-methylcholanthrene, chlordane, and methyltestosterone as stimulators of hepatic microsomal enzyme systems in the rat.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Chlordan; In Vitro Techniques; Liver; Methylcholanthrene; Methyltestosterone; Microsomes; Mixed Function Oxygenases; NADP; Oxidoreductases; Rats; Subcellular Fractions; Zoxazolamine | 1966 |
Studies on P-450. I. Preparation and properties of a submitochondrial particulate fraction from bovine adrenal cortex.
Topics: Adrenal Glands; Animals; Carbon Monoxide; Cattle; Cyanides; Cytochromes; Desoxycorticosterone; Electron Transport Complex IV; In Vitro Techniques; Microscopy, Electron; Mitochondria; Mixed Function Oxygenases; NADP; Sulfites | 1966 |
Studies on the metabolism of diethyl 4-nitrophenyl phosphorothionate (parathion) in vitro.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Chromatography, Thin Layer; Enzymes; Female; Guinea Pigs; In Vitro Techniques; Liver; Male; Mice; Microsomes; NADP; Nitrogen; Nitrophenols; Oxygen; Parathion; Phenobarbital; Phosphates; Phosphorus Isotopes; Rats | 1967 |
Spectral studies of drug interaction with hepatic microsomal cytochrome.
Topics: Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Hexobarbital; In Vitro Techniques; Kinetics; Liver; Microsomes; NADP; Oxidoreductases; Rats; Spectrophotometry | 1967 |
Magnetic and spectrophotometric properties of the microsomal carbon monoxide binding pigment.
Topics: Animals; Carbon Monoxide; Chlordan; Coloring Agents; Cytochromes; DDT; Diphenhydramine; Electron Spin Resonance Spectroscopy; Fasting; Ferrocyanides; Hydrogen-Ion Concentration; Liver; Microsomes; NAD; NADP; Oxygen; Phenobarbital; Phenytoin; Pigments, Biological; Rabbits; Rats; Spectrophotometry | 1967 |
Studies on the mechanism of action of mammalian hepatic azoreductase. II. The effects of phenobarbital and 3-methylcholanthrene on carbon monoxide sensitive and insensitive azoreductase activities.
Topics: Animals; Azo Compounds; Carbon Monoxide; Cytochromes; Female; Lipase; Liver; Methylcholanthrene; Microsomes; NADP; Organ Size; Oxidoreductases; Phenobarbital; Rats; Tetrazolium Salts | 1967 |
[On the hydrogen-activating system of Hydrogenomonas H 16. I. Distribution of the hydrogenase activity between two cellular fractions].
Topics: Carbon Monoxide; Cell-Free System; Cyanides; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; NAD; NADP; Oxidoreductases; Pseudomonas; Ultracentrifugation | 1966 |
Role of hemoprotein P-450 in fatty acid omega-hydroxylation in a soluble enzyme system from liver microsomes.
Topics: Animals; Carbon Monoxide; Chromatography, Ion Exchange; Cytochromes; Fatty Acids; Hot Temperature; Liver; Microsomes; NADP; Oxidoreductases; Oxygen; Proteins; Rabbits; Spectrum Analysis | 1968 |
Enzymic studies of bile acid metabolism. I. 6-beta-Hydroxylation of chenodeoxycholic and taurochenodeoxycholic acids by microsomal preparations of rat liver.
Topics: Animals; Bile Acids and Salts; Carbon Isotopes; Carbon Monoxide; Chromatography, Paper; Copper; Cytochromes; Hydrogen-Ion Concentration; In Vitro Techniques; Light; Liver; Microsomes; NADP; Oxygen; Rats; Spectrophotometry; Sulfur; Taurine | 1968 |
On the fatty acid and hydrocarbon hydroxylation in rat liver microsomes.
Topics: Alkanes; Aminopyrine; Animals; Carbon Monoxide; Cytochromes; Depression, Chemical; Fatty Acids; Fluorometry; Liver; Male; Microsomes; NADP; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Pigments, Biological; Rats; Stimulation, Chemical; Testosterone | 1968 |
On the properties of the 12 alpha-hydroxylase in cholic acid biosynthesis. Bile acids and steroids. 198.
Topics: Age Factors; Animals; Bile Acids and Salts; Carbon Isotopes; Carbon Monoxide; Chelating Agents; Cholestanes; Cholesterol; Chromatography, Gel; Chromatography, Thin Layer; Female; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Hydrogen-Ion Concentration; Liver; Magnesium; Male; Microsomes; Mixed Function Oxygenases; NAD; NADP; Quinacrine; Rats; Sex Factors; Time Factors; Tritium | 1968 |
Cytochrome P450 and steroid 11beta-hydroxylation in mitochondria from human adrenal cortex.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Antimycin A; Breast Neoplasms; Carbon Monoxide; Cushing Syndrome; Cytochromes; Electron Transport; Humans; Malates; Metyrapone; Mitochondria; Mixed Function Oxygenases; NAD; NADP; Spectrophotometry; Stereoisomerism; Stimulation, Chemical; Succinates | 1968 |
Studies on reduction of azo-linkages in human placental homogenates.
Topics: Azo Compounds; Carbon Monoxide; Edetic Acid; Female; Flavins; Glucosephosphate Dehydrogenase; Glutathione; Hexosephosphates; Humans; Hydrogen-Ion Concentration; Magnesium; NAD; NADP; Niacinamide; Oxygen; Phosphogluconate Dehydrogenase; Placenta; Pregnancy; Sulfhydryl Compounds | 1968 |
The action of paraquat and diquat on the respiration of liver cell fractions.
Topics: Amobarbital; Antimycin A; Carbon Monoxide; Catalase; Chloromercuribenzoates; Flavins; Herbicides; Hydrogen Peroxide; Hydroxybutyrates; Liver; Membranes; Microsomes; Mitochondria, Liver; NAD; NADP; Oxidoreductases; Oxygen Consumption; Pyridines; Quaternary Ammonium Compounds; Stimulation, Chemical; Succinates | 1968 |
Properties of a submicrosomal particle containing P-450 and flavoprotein.
Topics: Adrenal Glands; Animals; Carbon Monoxide; Cattle; Cyanides; Cytochromes; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Liver; Methods; Microsomes; NADP; Nitric Oxide; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Pigments, Biological; Proteins; Rabbits; Riboflavin; Spectrophotometry | 1968 |
Substrate-inducible microsomal aryl hydroxylase in mammalian cell culture. I. Assay and properties of induced enzyme.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Calcium; Carbon Monoxide; Carcinogens; Cricetinae; Culture Techniques; Edetic Acid; Enzyme Induction; Female; Fetus; Fluorescence; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Magnesium; Manganese; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Spectrum Analysis; Trypsin | 1968 |
Participation of the microsomal electron transport system involving cytochrome P-450 in omega-oxidation of fatty acids.
Topics: Animals; Antibodies; Antigens; Carbon Monoxide; Depression, Chemical; Electron Transport; Fatty Acids; Liver; Male; Microsomes; NADP; Oxidation-Reduction; Pigments, Biological; Rabbits; Rats; Stearic Acids | 1968 |
Relationship between the interconversion of cytochrome P-450 and P-420 and its activities in hydroxylations and demethylations by P-450 oxidase systems.
Topics: Adrenal Glands; Alcohols; Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cattle; Chickens; Cytochromes; Detergents; Electron Spin Resonance Spectroscopy; Guinea Pigs; Hydroxyprogesterones; Kidney; Kinetics; Liver; Lung; Male; Microsomes; NAD; NADP; Nitrobenzenes; Oxidoreductases; Rabbits; Rats; Spectrum Analysis; Swine | 1969 |
Mechanism of aliphatic hydroxylation. Tetralin hydroperoxide as an intermediate in the hydroxylation of tetralin in rat-liver homogenate.
Topics: Animals; Azides; Benzoates; Carbon Monoxide; Catalase; Chloromercuribenzoates; Chromatography, Gas; Cytochromes; Heme; Hemoglobins; Hydrogen-Ion Concentration; Iron; Kinetics; Liver; Male; Mercury; Models, Biological; Models, Chemical; NADP; Naphthalenes; Peroxidases; Peroxides; Rats | 1968 |
[On 2-benzolsulfonylamino-5 (beta-methoxyethoxy) pyrimidine (Glycodiazin). VII. On the mechanism of demethylation of Glycodiazin].
Topics: Animals; Buffers; Carbon Monoxide; Cyanides; Cytoplasm; Edetic Acid; Hydrogen-Ion Concentration; Hypoglycemic Agents; Kidney; Liver; Male; Metals; Microsomes; NADP; Oxygen; Phenanthrolines; Potassium; Proadifen; Rats; Sulfonamides | 1968 |
[Metabolism and mechanism of action of estrogens. XI. Metabolism of (4-14C)2-hydroxy-estrone in rat liver microsomes].
Topics: Air; Animals; Biotransformation; Carbon Isotopes; Carbon Monoxide; Carcinoma, Hepatocellular; Chloromercuribenzoates; Estrogens; Hot Temperature; Liver; Liver Neoplasms; Microsomes; NADP; Neoplasms, Experimental; Rats | 1969 |
N-demethylation of the chemosterilant HEMPA by ouse fly microscomes.
Topics: Animals; Carbon Monoxide; Chemosterilants; Houseflies; In Vitro Techniques; Insect Control; Microsomes; NADP; Oxygen; Phosphoric Acids; Proadifen; Rats; Serum Albumin, Bovine | 1968 |
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates | 1969 |
Studies on the relationship between the effects of various substances on absorption spectrum of cytochrome P-450 and the reduction of p-nitrobenzoate by mouse liver microsomes.
Topics: Aminopyrine; Aniline Compounds; Animals; Benzoates; Carbon Monoxide; Cytochromes; Ethylamines; Hexobarbital; Imidazoles; In Vitro Techniques; Kinetics; Liver; Male; Mice; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Oxidoreductases; Proadifen; Pyridines; Spectrophotometry | 1969 |
Resolution of the cytochrome P-450-containing omega-hydroxylation system of liver microsomes into three components.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Cytochromes; Depression, Chemical; Drug Stability; Electron Spin Resonance Spectroscopy; Fatty Acids; Guinea Pigs; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Lipid Metabolism; Liver; Male; Microsomes; NAD; NADP; Oxidoreductases; Phenobarbital; Rabbits; Rats; Solubility; Spectrophotometry; Stimulation, Chemical | 1969 |
Sulphite reductase from bakers' yeast: a haemoflavoprotein.
Topics: Benzoates; Carbon Monoxide; Cell-Free System; Chromatography, Gel; Chromatography, Ion Exchange; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Heme; Kinetics; Light; Methods; NADP; Nitrobenzenes; Oxidoreductases; Plant Proteins; Riboflavin; Saccharomyces; Spectrum Analysis; Sulfites; Sulfur Isotopes | 1969 |
Some properties and distribution of the omega-hydroxylation system of medium-chain fatty acids.
Topics: Animals; Anura; Carbon Isotopes; Carbon Monoxide; Cattle; Chromatography, Gas; Chromatography, Thin Layer; Columbidae; Cyanides; Cyprinidae; Cytochromes; Dogs; Fatty Acids; Guinea Pigs; Humans; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Lung; Male; Mice; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Proadifen; Rabbits; Rats; Salts; Species Specificity; Swine | 1969 |
Microsomal hydroxylation of decane.
Topics: Alcohols; Alkanes; Aniline Compounds; Animals; Carbon Isotopes; Carbon Monoxide; Cattle; Chick Embryo; Columbidae; Cyanides; Fatty Acids; Glycols; Hydrogen-Ion Concentration; Kidney; Kinetics; Liver; Lung; Male; Mice; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Phenobarbital; Proadifen; Rabbits; Rats | 1969 |
Oxidation of n-hexadecane by mouse liver microsomal fraction.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Chromatography, Thin Layer; Hydrocarbons; Liver; Male; Mice; Microsomes; NADP; Oxidation-Reduction; Oxygen | 1969 |
Ethanol oxidation in the microsomal fraction of rat liver.
Topics: Acetaldehyde; Animals; Azides; Biphenyl Compounds; Carbon Monoxide; Catalase; Cattle; Cyanides; Cytochromes; Depression, Chemical; Ethanol; Glucose; Glucose Oxidase; Liver; Male; Microsomes; NADP; Peroxides; Proadifen; Rats; Stimulation, Chemical; Triazoles | 1969 |
The role of mixed function oxidases in kaurene metabolism in Echinocystis macrocarpa Greene endosperm.
Topics: Acids; Alcohols; Aldehydes; Carbon Isotopes; Carbon Monoxide; Cytochromes; Depression, Chemical; Gibberellins; Light; Manometry; NADP; Oxidoreductases; Oxygen Consumption; Oxygen Isotopes; Plants; Seeds; Spectrophotometry; Terpenes | 1969 |
Significance of mixed oxygenases and nitroreductase in drug metabolism.
Topics: Animals; Anthelmintics; Carbon Monoxide; Carbon Tetrachloride; Chemical Phenomena; Chemistry; Cytochromes; Haplorhini; Imidazoles; Microsomes, Liver; NADP; Nitrogen; Oxidation-Reduction; Oxidoreductases; Oxygenases; Pharmaceutical Preparations; Phenobarbital | 1969 |
Influence of phenobarbital pretreatment on the in vitro ring A reduction of delta4-3-oxo-steroids in rat liver microsomes.
Topics: 17-Ketosteroids; Androstanes; Animals; Carbon Isotopes; Carbon Monoxide; Chloromercuribenzoates; Chromatography, Thin Layer; Cyanides; Cytochromes; In Vitro Techniques; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenobarbital; Rats; Stimulation, Chemical | 1969 |
Microsomal heme oxygenase. Characterization of the enzyme.
Topics: Animals; Azides; Benzoates; Bilirubin; Brain; Carbon Monoxide; Cyanides; Depression, Chemical; Detergents; Deuterium; Heme; Hemoglobins; In Vitro Techniques; Kidney; Kinetics; Lipase; Lung; Male; Mercury; Methods; Microsomes; Microsomes, Liver; Myoglobin; NADP; Oxygen Consumption; Oxygenases; Phospholipases; Porphyrins; Rats; Spleen; Time Factors; Trypsin | 1969 |
Reductive dechlorination of pp'DDT by pigeon liver microsomes.
Topics: Animals; Carbon Monoxide; Columbidae; Cytochromes; DDT; Electron Transport Complex IV; In Vitro Techniques; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen | 1969 |
Oxidative demethylation of N-methylhydrazines by rat liver microsomes.
Topics: Animals; Azo Compounds; Bile Acids and Salts; Carbon Monoxide; Cytochromes; Formaldehyde; Hot Temperature; Hydrazines; In Vitro Techniques; Lipase; Methylcholanthrene; Microsomes, Liver; NADP; Oxygen Consumption; Pancreatic Juice; Phenobarbital; Proadifen; Rats | 1969 |
Purification of ctochrome b5-ike hemoprotein from anaerobically grown yeast.
Topics: Air; Carbon Monoxide; Culture Media; Cytochromes; Heme; Methods; NAD; NADP; Oxidation-Reduction; Pigments, Biological; Plant Proteins; Saccharomyces; Solubility; Spectrum Analysis; Trypsin | 1969 |
Microsomal cytochromes b5 and P450 during induction of aryl hydrocarbon hydroxylase activity in mammalian cell culture.
Topics: Animals; Benz(a)Anthracenes; Carbon Monoxide; Cricetinae; Culture Techniques; Cycloheximide; Cytochromes; Depression, Chemical; Enzyme Activation; Enzyme Induction; Female; Fetus; Heme; Hydrocarbons; Liver; Maternal-Fetal Exchange; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; NADP; Pigments, Biological; Pregnancy; Protein Biosynthesis; Rats; Spectrophotometry; Stimulation, Chemical; Time Factors | 1970 |
Preparation and physicochemical properties of functional hemoprotein P450 from mammalian tissue microsomes.
Topics: Adrenal Glands; Animals; Carbon Monoxide; Cattle; Chemical Phenomena; Chemistry; Cytochromes; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Imidazoles; Male; Methods; Microsomes; Microsomes, Liver; Models, Chemical; NADP; Nitroso Compounds; Osmolar Concentration; Oxidation-Reduction; Pigments, Biological; Protein Denaturation; Rabbits; Solubility; Spectrophotometry; Swine; Temperature; Triazoles; Trypsin; Ultraviolet Rays | 1970 |
Hydroxylation of oleic acid by cell-free extracts of a species of torulopsis.
Topics: Azides; Carbon Isotopes; Carbon Monoxide; Cell-Free System; Crystallization; Cyanides; Glycerol; Hydrogen-Ion Concentration; Kinetics; Mixed Function Oxygenases; NAD; NADP; Oleic Acids; Oxygen; Ultracentrifugation; Yeasts | 1970 |
Effect of 4,4-dideuteration of reduced nicotinamide-adenine dinucleotide phosphate on the mixed function oxidases of hepatic microsomes.
Topics: Adenine Nucleotides; Aniline Compounds; Animals; Carbon Monoxide; Deuterium; Electron Transport; Electron Transport Complex IV; Glucosephosphate Dehydrogenase; Hexokinase; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidoreductases; Oxygen Consumption; Rats | 1970 |
Is atherosclerosis a disorder of intramitochondrial respiration?
Topics: Arteriosclerosis; Carbon Monoxide; Electron Transport; Electron Transport Complex IV; Fatty Acids; Humans; Lipid Metabolism; Lipids; Mitochondria; Mitochondria, Liver; NAD; NADP; Oxidation-Reduction; Oxygen Consumption; Smoking | 1970 |
Phosphatidylcholine requirement in the enzymatic reduction of hemoprotein P-450 and in fatty acid, hydrocarbon, and drug hydroxylation.
Topics: Alkanes; Animals; Benzphetamine; Carbon Monoxide; Electron Transport; Fatty Acids; Heme; Kinetics; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Phosphatidylcholines; Rats; Spectrophotometry | 1970 |
Respiration and protein synthesis in Escherichia coli membrane-envelope fragments. 3. Electron microscopy and analysis of the cytochromes.
Topics: Carbon Monoxide; Cytochromes; Electron Transport; Escherichia coli; Membranes; Microscopy, Electron; NADP; Spectrum Analysis; Succinates; Ultracentrifugation | 1970 |
Characterization of the particulate nitrite oxidase and its component activities from the chemoautotroph Nitrobacter agilis.
Topics: Azides; Carbon Monoxide; Cell Membrane; Chelating Agents; Chemical Phenomena; Chemistry; Cold Temperature; Cyanides; Cytochromes; Electron Transport; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Light; NADP; Nitrates; Nitrites; Nitrobacter; Oxidoreductases; Oxygen; Protein Denaturation; Spectrophotometry; Succinates; Sulfides | 1970 |
Oxidation of 5 beta-cholestane-3alpha, 7alpha, 12alpha-triol by rat liver microsomes.
Topics: Alcohols; Animals; Bile; Biliary Fistula; Carbon Isotopes; Carbon Monoxide; Cholestanes; Chromatography, Gas; Chromatography, Thin Layer; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Rats; Spectrophotometry; Tritium | 1970 |
[Hydroxylation of progesterone by rabbit liver microsomes. Changes in metabolite pattern after phenobarbital treatment of the animals].
Topics: Animals; Biotransformation; Carbon Monoxide; Chromatography, Gel; Chromatography, Paper; Cytochromes; Enzyme Induction; Female; Freezing; Hydrogen-Ion Concentration; Hydroxyprogesterones; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenobarbital; Progesterone; Rabbits | 1970 |
Studies on the kinetics of cytochrome P-450 reduction in rat liver microsomes.
Topics: Alcohols; Animals; Carbon Monoxide; Cyclohexanes; Cytochromes; Kinetics; Microsomes, Liver; Models, Chemical; NADP; Oxidoreductases; Rats; Spectrum Analysis | 1970 |
[Behavior of different microsomal drug oxidations following inactivation of cytochrome P-450 by UV-irradiation or deoxycholate treatment].
Topics: Aniline Compounds; Animals; Bile Acids and Salts; Biotransformation; Carbon Monoxide; Cytochromes; In Vitro Techniques; Male; Microsomes, Liver; NADP; Rabbits; Radiation Effects; Ultraviolet Rays | 1970 |
Omega- and (omega - 1)-oxidation of fatty acids by rat liver microsomes.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Chromatography, Gas; Depression, Chemical; Dicarboxylic Acids; Fatty Acids; Male; Microsomes, Liver; NAD; NADP; Oxidoreductases; Palmitic Acids; Phenobarbital; Rats; Spectrum Analysis; Stearic Acids; Stimulation, Chemical; Tritium | 1970 |
Biochemical characteristics of insect microsomes: NADPH oxidation by intact microsomes from the housefly, Musca domestica.
Topics: Animals; Carbon Monoxide; Chloromercuribenzoates; Copper; Cyanides; Cytochromes; Depression, Chemical; Ethylmaleimide; Female; Houseflies; Iodoacetates; Kinetics; Male; Microsomes; NAD; NADP; Oxidoreductases; Proadifen; Pyridines; Pyrroles; Stimulation, Chemical; Sulfhydryl Compounds; Zinc | 1970 |
Model systems for aromatic nitro group reduction--relationships to tissue catalyzed reagents.
Topics: Aminobenzoates; Animals; Benzoates; Biological Transport, Active; Blood; Carbon Monoxide; Cysteine; Dialysis; Electrons; Female; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Glutathione; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Indicators and Reagents; Liver; Male; Mice; Models, Biological; NAD; NADP; Oxidation-Reduction; Placenta; Pregnancy; Rats; Tissue Extracts | 1970 |
[Studies on the binding of carbon monoxide with liver microsomal P-450 reduced by NADPH].
Topics: Animals; Carbon Monoxide; In Vitro Techniques; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Pigments, Biological; Protein Binding; Rats; Time Factors | 1971 |
The metabolism of aromatic compounds in higer plants. X. Properties of the cinnamic acid 4-hydroxylase of pea seedlings and some aspects of its metabolic and developmental control.
Topics: Azides; Carbon Isotopes; Carbon Monoxide; Chelating Agents; Chromatography, Paper; Cinnamates; Cyanides; Drug Stability; Edetic Acid; Enzyme Induction; Folic Acid; Glucosephosphate Dehydrogenase; Glycerol; Hydrogen-Ion Concentration; Kinetics; Light; Mercaptoethanol; Microsomes; Mixed Function Oxygenases; NADP; Phenols; Plant Cells; Plant Development; Plants; Pyridines; Radiation Effects; Temperature; Ultracentrifugation | 1971 |
On the inhibitory action of mersalyl on microsomal drug oxidation: a rigid organization of the electron transport chain.
Topics: Animals; Carbon Monoxide; Chlorides; Cytochromes; Dealkylation; Electron Transport; Fasting; Formaldehyde; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Magnesium; Male; Mercury; Microsomes, Liver; Morphinans; NAD; NADP; Organomercury Compounds; Osmolar Concentration; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Phenobarbital; Phosphates; Polarography; Potassium Chloride; Rats; Spectrophotometry; Time Factors; Tromethamine; Ultracentrifugation | 1971 |
Fatty acid inducible cy tochrome P-454 of rat kidney cortex microsomes.
Topics: Aminopyrine; Animals; Carbon Monoxide; Cytochromes; Dietary Fats; Electron Transport; Fatty Acids, Nonesterified; Kidney; Male; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxidoreductases; Phenobarbital; Rats; Spectrophotometry; Sulfites; Testosterone | 1970 |
Microsomal epoxidation of aldrin in lepidopterous larvae.
Topics: Aerobiosis; Animals; Ascorbic Acid; Carbon Monoxide; Cattle; Chromatography, Gas; Cyanides; Cytochromes; Dieldrin; Edetic Acid; Ethers, Cyclic; Hydrocarbons, Halogenated; Insecta; Insecticides; Kinetics; Larva; Microsomes; NADP; Naphthalenes; Niacinamide; Oxidation-Reduction; Potassium; Proadifen; Serum Albumin, Bovine; Species Specificity; Spectrophotometry; Ultracentrifugation; Urea; Valerates | 1970 |
Cytochromes in bovine liver nuclear membranes.
Topics: Animals; Carbon Monoxide; Cattle; Cell Nucleus; Centrifugation, Density Gradient; Cytochromes; Electron Transport Complex IV; Liver; Membranes; Microsomes, Liver; Mitochondria, Liver; NADP; Oxidation-Reduction; Oxidoreductases; Spectrophotometry; Succinate Dehydrogenase; Sulfites | 1971 |
Oxidation of cholesterol, 3 -hydroxy-5-pregnen-20-one and 3 -hydroxy-5-androsten-17-one by rat liver microsomes.
Topics: Animals; Biliary Fistula; Carbon Monoxide; Cholesterol; Chromatography, Gas; Dehydroepiandrosterone; In Vitro Techniques; Linoleic Acids; Lipid Metabolism; Male; Mass Spectrometry; Microsomes, Liver; NADP; Oxidation-Reduction; Phenobarbital; Pregnanes; Rats | 1971 |
The cholesterol side-chain cleavage enzyme system in mitochondria of human term placenta.
Topics: Carbon Isotopes; Carbon Monoxide; Cell Fractionation; Cholesterol; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cytochromes; Enzyme Inhibitors; Enzymes; Female; Flavoproteins; Freeze Drying; Humans; Kinetics; Light; Lipids; Mercaptoethylamines; Microsomes; Mitochondria; NADP; Oxygen Consumption; Phosphates; Phosphatidylcholines; Phosphatidylethanolamines; Placenta; Pregnancy; Pregnenolone; Progesterone; Temperature; Ultracentrifugation; Ultrasonics | 1971 |
Inability of substrates to alter the carbon monoxide and ethyl isocyanide difference spectra of microsomal hemoprotein.
Topics: Aniline Compounds; Animals; Benzopyrenes; Carbon Monoxide; Chromatography, Thin Layer; Cyanides; Cytochromes; Male; Methylcholanthrene; Microsomes, Liver; NADP; Rats; Spectrophotometry | 1971 |
Cytochrome P450 and steroid 21-hydroxylation in microsomes from human adrenal cortex.
Topics: 17-Ketosteroids; Adrenal Glands; Androstanes; Carbon Monoxide; Cytochromes; Humans; Hydroxyprogesterones; Kinetics; Microsomes; NADP; Pregnanes; Pregnenolone; Progesterone; Protein Binding; Spectrophotometry | 1971 |
The role of microsomes in the hepatic metabolism of ethanol.
Topics: Acetates; Adenine Nucleotides; Aerobiosis; Amino Alcohols; Anaerobiosis; Animals; Azides; Bile Acids and Salts; Carbon Monoxide; Catalase; Cell Fractionation; Chlorides; Chloromercuribenzoates; Copper; Cyanides; Diet; Dimethyl Sulfoxide; Edetic Acid; Ethanol; Female; Hot Temperature; Hydrogen Peroxide; Iron; Liver; Mercury; Microsomes, Liver; NAD; NADP; Oxidoreductases; Phenobarbital; Pyrazoles; Rats; Sulfides; Triazoles | 1971 |
Evidence for a different CO-binding pigment in solubilized rat hepatic microsomes.
Topics: Aminopyrine; Animals; Bile Acids and Salts; Carbon Monoxide; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Cytochromes; Drug Stability; Hemoglobins; Male; Microsomes, Liver; NADP; Oxidoreductases; Potassium Chloride; Protein Binding; Rats; Spectrophotometry; Sulfites; Ultracentrifugation | 1971 |
Enzymatic reduction of niridazole by rat liver microsomes.
Topics: Aerobiosis; Animals; Anthelmintics; Carbon Monoxide; Chemical Precipitation; Chromatography, Gas; Cytochromes; Guinea Pigs; Hydroxylamines; Imidazoles; Ketones; Lipase; Liver; Male; Mass Spectrometry; Methylcholanthrene; Mice; Microsomes, Liver; NAD; NADP; Nitro Compounds; Nitrogen; Oxidation-Reduction; Oxidoreductases; Oxygen; Pancreatic Juice; Phenobarbital; Quaternary Ammonium Compounds; Rabbits; Rats; Species Specificity; Spectrophotometry; Sulfates; Tetrazolium Salts; Thiazoles | 1971 |
Activation of slaframine by liver microsomes and flavins.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Basidiomycota; Biological Assay; Carbon Monoxide; Cell Fractionation; Chemical Phenomena; Chemistry; Drug Stability; Flavin Mononucleotide; Flavins; Guinea Pigs; Hot Temperature; Hydrogen-Ion Concentration; Ileum; In Vitro Techniques; Kinetics; Light; Liver; Male; Mice; Microsomes, Liver; Mitochondria, Liver; Muscle Contraction; NADP; Nerve Fibers, Myelinated; Oxidation-Reduction; Parasympathomimetics; Photochemistry; Radiation Effects; Rats; Receptors, Cholinergic; Salivation; Ultracentrifugation | 1971 |
Preparation and properties of a solubilized form of cytochrome P-450 from chick embryo liver microsomes.
Topics: Acetamides; Allyl Compounds; Animals; Bacillus subtilis; Carbon Monoxide; Cell Fractionation; Chick Embryo; Cytochromes; Depression, Chemical; Detergents; Etiocholanolone; Female; Flavins; Heme; Ketosteroids; Liver; Methods; Methylcholanthrene; Microsomes, Liver; NAD; NADP; Nitrogen; Oxidoreductases; Peptide Hydrolases; Phenobarbital; Pregnanes; Rats; Solubility; Spectrophotometry; Stimulation, Chemical | 1971 |
A fatty acid gamma-hydroxylation system solubilized from porcine kidney cortex microsomes.
Topics: Alkanes; Animals; Bile Acids and Salts; Carbon Isotopes; Carbon Monoxide; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Cytochromes; Ethyl Ethers; Fatty Acids, Nonesterified; Ferredoxins; Hydrogen-Ion Concentration; Hydroxylation; Kidney; Kinetics; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phospholipids; Plants; Protein Binding; Solubility; Spectrophotometry; Sulfites; Surface-Active Agents; Swine; Xylenes | 1971 |
Oxygen uptake by microsomal preparations from the housefly, Musca domestica.
Topics: Animals; Anisoles; Carbon Monoxide; Cyanides; Cytochromes; Depression, Chemical; Dioxoles; Houseflies; Hydrogen-Ion Concentration; Kinetics; Mercury; Microsomes; NAD; NADP; Nitro Compounds; Organometallic Compounds; Oxygen Consumption; Polarography; Potassium; Proadifen; Sulfhydryl Reagents; Sulfonic Acids; Sulfoxides | 1971 |
Oxidation-reduction mechanisms of cytochrome P-450.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Cytochromes; Electron Spin Resonance Spectroscopy; Kinetics; Microsomes, Liver; Mixed Function Oxygenases; Models, Biological; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Potassium; Protein Binding; Rabbits; Spectrophotometry; Sulfites | 1971 |
The stimulatory effects of carbon tetrachloride on peroxidative reactions in rat liver fractions in vitro. Interaction sites in the endoplasmic reticulum.
Topics: Aldehydes; Aminopyrine; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloromercuribenzoates; Cytochromes; Electron Transport; Endoplasmic Reticulum; In Vitro Techniques; Lipid Metabolism; Liver; Malonates; Microsomes, Liver; NADP; Niacinamide; Peroxides; Proadifen; Rats | 1971 |
Formation of a factor lethal for S. typhimurium TA1530 and TA1531 on incubation of aflatoxin B 1 with rat liver microsomes.
Topics: Aflatoxins; Aniline Compounds; Animals; Carbon Monoxide; Caseins; Chromatography, Thin Layer; Depression, Chemical; Diet; Male; Microsomes, Liver; NADP; Nitrogen; Oxygen Consumption; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Salmonella typhimurium | 1971 |
The inhibitory effect of metyrapone on cytochrome P-450-catalyzed mixed-function oxidation reactions as compared to the effect of carbon monoxide.
Topics: Carbon Monoxide; Cytochromes; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction | 1971 |
Significance of the steroid-induced type I spectral change in steroid C-21 hydroxylase system of bovine adrenocortical microsomes.
Topics: 17-Ketosteroids; Adrenal Glands; Aerobiosis; Anaerobiosis; Androstanes; Animals; Carbon Isotopes; Carbon Monoxide; Cattle; Cytochromes; Hydroxyprogesterones; Microsomes; Mixed Function Oxygenases; Models, Biological; NADP; Oxygen Consumption; Spectrophotometry; Steroids; Surface-Active Agents; Tritium | 1971 |
The conversion of pyrrolizidine alkaloids to N-oxides and to dihydropyrrolizine derivatives by rat-liver microsomes in vitro.
Topics: Alkaloids; Animals; Calcium; Carbon Monoxide; DDT; Diet; Kinetics; Lung; Magnesium; Manganese; Microsomes; Microsomes, Liver; Models, Biological; NADP; Niacinamide; Oxides; Oxygen; Phenobarbital; Proadifen; Proteins; Pyrroles; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains | 1971 |
Incorporation of radioactive- -aminolevulinic acid into microsomal cytochrome P 450 : selective breakdown of the hemoprotein by allylisopropylacetamide and carbon tetrachloride.
Topics: Acetamides; Allyl Compounds; Amides; Amino Acids; Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochromes; Heme; Kinetics; Levulinic Acids; Male; Microsomes, Liver; NADP; Oxidoreductases; Protein Binding; Proteins; Rats; Spectrophotometry; Tritium | 1972 |
Liver metabolic reactions: tertiary amine N-dealkylation, tertiary amine N-oxidation, N-oxide reduction, and N-oxide N-dealkylation. I. Tricyclic tertiary amine drugs.
Topics: Amitriptyline; Animals; Carbon Isotopes; Carbon Monoxide; Chlorpromazine; Cyclic N-Oxides; Cytochromes; Dealkylation; Desipramine; Horses; Imipramine; Kinetics; Liver; Male; NADP; Organ Specificity; Oxidation-Reduction; Proadifen; Rats; Species Specificity; Subcellular Fractions; Swine; Tetrazolium Salts | 1972 |
Influence of 2,4-dichloro-6-phenoxyethyl-amine (DPEA) and -diethylaminoethyl diphenylpropylacetate (SKF-525A) on hepatic microsomal azoreductase activity from phenobarbital or 3-methylcholanthrene induced rats.
Topics: Animals; Azo Compounds; Carbon Monoxide; Chlorine; Cytochromes; Enzyme Activation; Enzyme Induction; Ethylamines; Flavin Mononucleotide; Male; Methylcholanthrene; Microsomes, Liver; NADP; Naphthalenes; Nitrogen; Oxidoreductases; Phenobarbital; Phenols; Proadifen; Rats; Rats, Inbred Strains; Sulfonamides; Sulfonic Acids | 1972 |
Factors involved in the inhibition of drug metabolism by (-)-emetine.
Topics: Aminopyrine; Aniline Compounds; Animals; Azo Compounds; Carbon Monoxide; Cytochromes; Dealkylation; Emetine; Female; In Vitro Techniques; Kinetics; Mercaptopurine; Metabolism; Microsomes, Liver; Morphinans; NADP; Nitrogen; Nucleosides; Oxidoreductases; Rats; Ribonucleosides; Tetrazolium Salts | 1971 |
A comparative study on the effects of phenobarbital and 3,4-benzpyrene on the hydroxylating enzyme system of rat-liver microsomes.
Topics: Aminopyrine; Animals; Benzopyrenes; Carbon Monoxide; Cytochromes; Enzyme Activation; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Rats; Rats, Inbred Strains; Spectrophotometry | 1969 |
Yeast hemoglobin-reductase complex.
Topics: Candida; Carbon Monoxide; Chromatography, DEAE-Cellulose; Chromatography, Gel; Electron Spin Resonance Spectroscopy; Electrophoresis; Flavin-Adenine Dinucleotide; Hemoglobins; Iron; Molecular Weight; NADP; Oxidation-Reduction; Oxidoreductases; Protein Binding; Spectrophotometry; Sulfites | 1972 |
NADH-dependent cytochrome P-450 oxidase system in submicrosomal particles.
Topics: Aerobiosis; Anaerobiosis; Animals; Carbon Monoxide; Cyanides; Cytochromes; Endoplasmic Reticulum; Ferricyanides; Free Radicals; Kinetics; Liver; Male; Membranes; Microsomes, Liver; Models, Biological; NAD; NADP; Oxidoreductases; Oxygen; Rabbits; Rotenone; Spectrophotometry; Tetrazolium Salts | 1972 |
Microbial oxidation of amines. Partial purification of a mixed-function secondary-amine oxidase system from Pseudomonas aminovorans that contains an enzymically active cytochrome-P-420-type haemoprotein.
Topics: Amines; Carbon Monoxide; Cytochromes; Electron Spin Resonance Spectroscopy; Ethylamines; Flavins; Formaldehyde; Hydrogen-Ion Concentration; Iron; Kinetics; Methylamines; Monoamine Oxidase; Monoamine Oxidase Inhibitors; NAD; NADP; Oxygen; Pseudomonas; Spectrophotometry | 1971 |
The effect of piperonyl butoxide concentration on the formation of cytochrome P-450 difference spectra in hepatic microsomes from mice.
Topics: Animals; Binding Sites; Carbon Monoxide; Cytochromes; Dioxoles; Hydrogen-Ion Concentration; Kinetics; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; NADP; Nitriles; Osmolar Concentration; Oxidation-Reduction; Piperonyl Butoxide; Protein Binding; Spectrophotometry; Spectrum Analysis | 1972 |
Cytochrome P 450K of rat kidney cortex microsomes: its involvement in fatty acid - and ( -1)-hydroxylation.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Chromatography, Gas; Cytochromes; Fatty Acids; Fatty Acids, Nonesterified; Hydroxylation; Kidney; Kinetics; Light; Male; Microsomes; Mixed Function Oxygenases; NAD; NADP; Oxidoreductases; Oxygen; Protein Binding; Radiation Effects; Rats; Spectrophotometry; Stereoisomerism | 1972 |
Enzymatic degradation of heme. Oxygenative cleavage requiring cytochrome P-450.
Topics: Animals; Carbon Monoxide; Cytochromes; Heme; Light; Male; Mass Spectrometry; Microsomes; Microsomes, Liver; NADP; Oxidoreductases; Oxygen; Oxygen Isotopes; Oxygenases; Photochemistry; Radiation Effects; Rats; Spleen; Water | 1972 |
Enzymatic dechlorination. Dechlorination of chloroethanes and propanes in vitro.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Chlorine; Enzyme Induction; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Radioisotopes; Rats; Ultracentrifugation | 1971 |
[Enzymatic luminescence of the microsomes of hepatocytes].
Topics: Animals; Carbon Monoxide; Cytochromes; Electron Transport; Flavoproteins; Heterocyclic Compounds; Luminescent Measurements; Microsomes, Liver; NAD; NADP; Phenobarbital; Rats; Time Factors | 1972 |
Monooxygenase drug metabolizing activity in CaCl 2 -aggregated hepatic microsomes from rat liver.
Topics: Aminopyrine; Aniline Compounds; Animals; Calcium Chloride; Carbon Monoxide; Chlorine; Dronabinol; Enzyme Induction; Male; Microsomes, Liver; Mixed Function Oxygenases; NADP; Oxidoreductases; Phenobarbital; Proadifen; Rats | 1972 |
Hepatic microsomal ethanol oxidation. Hydrogen peroxide formation and the role of catalase.
Topics: Acetaldehyde; Amitrole; Animals; Azides; Carbon Monoxide; Catalase; Cytochromes; Ethanol; Hydrogen Peroxide; Male; Microsomes, Liver; NADP; Oxidoreductases; Oxygen Consumption; Pyrazoles; Rats | 1972 |
Aryl hydrocarbon (benzopyrene) hydroxylase is stimulated in human lymphocytes by mitogens and benz(a)anthracene.
Topics: Benz(a)Anthracenes; Benzopyrenes; Carbon Monoxide; Enzyme Induction; Humans; Hydrocarbons; In Vitro Techniques; Lectins; Lymphocytes; Mitosis; Mixed Function Oxygenases; NADP; Plant Lectins; Plants | 1972 |
On the rate-limiting step in microsomal hydroxylation of steroids.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Chemical Phenomena; Chemistry; Deuterium; Hydroxylation; Hydroxysteroids; Kinetics; Male; Microsomes, Liver; NADP; Pregnenolone; Rats; Sterols; Testosterone; Tritium; Water | 1972 |
Evidence for a mixed function oxidase in the biosynthesis of ethanolamine plasmalogens from 1-alkyl-2-acyl-sn-glycero-3-phosphorylethanolamine.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Carcinoma, Ehrlich Tumor; Chromatography, Thin Layer; Cyanides; Fatty Alcohols; Isotope Labeling; NAD; NADP; Neoplasms, Experimental; Oxidoreductases; Oxygen; Phospholipases; Phospholipids; Plasmalogens; Rats; Sarcoma; Subcellular Fractions | 1972 |
[Functions of iron-sulfur proteins in energy metabolism].
Topics: Adenosine Triphosphate; Bacterial Proteins; Carbon Monoxide; Clostridium; Electron Transport; Electron Transport Complex IV; Ferredoxins; Glucose; Glycolysis; Iron; Light; Metalloproteins; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Pyruvates; Saccharomyces; Sulfur | 1972 |
Interaction of oxygen and aromatic amines with hepatic microsomal mixed-function oxidase.
Topics: Aniline Compounds; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Female; Glucosephosphate Dehydrogenase; Glucosephosphates; Hydrogen-Ion Concentration; Hydroxylation; In Vitro Techniques; Kinetics; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen; Protein Binding; Rabbits | 1972 |
Studies on the biosynthesis of 18-oxygenated steroids from exogenous corticosterone by domestic duck (Anas platyrhynchos) adrenal gland mitochondria.
Topics: Adrenal Glands; Aldosterone; Aminopterin; Animals; Calcium; Carbon Isotopes; Carbon Monoxide; Chloromercuribenzoates; Corticosterone; Cytochrome P-450 Enzyme System; Ducks; Enzyme Activation; Hydroxycorticosteroids; Kinetics; Magnesium; Male; Metyrapone; Mitochondria; NADP; Potassium; Sodium; Structure-Activity Relationship; Tritium | 1972 |
[Adrenal gland 21-hydroxylase from the domestic duck (Anas platyrhynchos)].
Topics: Adrenal Glands; Animals; Carbon Isotopes; Carbon Monoxide; Chloromercuribenzoates; Cytochrome c Group; Cytochrome P-450 Enzyme System; Ducks; Hydroxyprogesterones; Kinetics; Metyrapone; Microsomes; Mixed Function Oxygenases; NADP; Progesterone; Species Specificity; Spectrophotometry; Structure-Activity Relationship; Temperature | 1972 |
Cholesterol 7 -hydroxylase in rat liver microsomal preparations.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Cholesterol; Chromatography, Thin Layer; Edetic Acid; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred WF; Steroid Hydroxylases; Tritium | 1972 |
[Formation of chloroform from carbon tetrachloride in liver microsomes, lipid peroxidation and destruction of cytochrome P-450].
Topics: Alcohols; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Desipramine; Disulfiram; Flavonoids; Linoleic Acids; Lipid Metabolism; Male; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Oxygenases; Piperonyl Butoxide; Rabbits; Rats; Ultraviolet Rays | 1972 |
Cytochrome P-450 in 7 -hydroxylation of taurodeoxycholic acid.
Topics: Animals; Bile Acids and Salts; Carbon Monoxide; Chromatography, Gas; Cytochrome P-450 Enzyme System; Deoxycholic Acid; Hydroxylation; Kinetics; Light; Male; Mathematics; Microsomes, Liver; Mixed Function Oxygenases; NADP; Phenobarbital; Rats; Taurocholic Acid | 1973 |
The monooxygenation of N-heptane by rat liver microsomes.
Topics: Aerobiosis; Alcohols; Alkanes; Animals; Carbon Monoxide; Chromatography, Gas; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Isomerism; Kinetics; Mass Spectrometry; Metyrapone; Microsomes, Liver; Myocardium; NADP; Oxidation-Reduction; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Swine; Vibration | 1972 |
Microsomal reduction of gentian violet. Evidence for cytochrome P-450-catalyzed free radical formation.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Free Radicals; Gentian Violet; In Vitro Techniques; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains | 1982 |
Examination of the oxidase function of the b-type cytochrome in human polymorphonuclear leucocytes.
Topics: Carbon Monoxide; Cytochrome b Group; Dithionite; Humans; Kinetics; Light; NADP; Neutrophils; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Peroxidase; Potassium Chloride | 1984 |
The cytochrome complement of Haemophilus parasuis.
Topics: Ascorbic Acid; Carbon Monoxide; Culture Media; Cytochromes; Haemophilus; Ligands; NAD; NADP; Nicotinamide Mononucleotide; Osmotic Pressure; Oxygen Consumption; Spectrophotometry; Succinates; Succinic Acid; Tetramethylphenylenediamine | 1984 |
Studies on nifurtimox nitroreductase activity in liver and other rat tissues.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Drug Interactions; Hot Temperature; In Vitro Techniques; Male; Microsomes, Liver; NADP; Nifurtimox; Nitrofurans; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains | 1984 |
Oxygenation of 18-hydroxycorticosterone as the final reaction for aldosterone biosynthesis.
Topics: 18-Hydroxycorticosterone; Adrenal Glands; Aldosterone; Animals; Carbon Monoxide; Cattle; Cells, Cultured; Corticosterone; Cytochrome P-450 Enzyme System; Malates; Mitochondria; NAD; NADP; Oxidation-Reduction; Radioimmunoassay | 1984 |
Variants of human microsomal enzymes.
Topics: Antipyrine; Carbon Monoxide; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Isoquinolines; Microsomes, Liver; Mixed Function Oxygenases; NADP; Polymorphism, Genetic | 1983 |
Identification of dichloromethyl carbene as a metabolite of carbon tetrachloride.
Topics: Alkenes; Animals; Carbon Monoxide; Carbon Tetrachloride; Cyclopropanes; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydrocarbons, Chlorinated; Male; Microsomes, Liver; NADP; Rats; Rats, Inbred Strains | 1983 |
De novo biosynthesis of 6 beta-hydroperoxyandrostenedione in human placental microsomes.
Topics: Androstenedione; Carbon Monoxide; Chromatography, High Pressure Liquid; Female; Humans; Hydroxymercuribenzoates; Kinetics; Microsomes; NADP; Oxygen; Placenta; Pregnancy | 1984 |
Cyanide-resistant respiration in a respiration-deficient mutant of Saccharomyces cerevisae.
Topics: Carbon Monoxide; Cyanides; Microsomes; Mitochondria; Mutation; NAD; NADP; Oxygen Consumption; Potassium Cyanide; Saccharomyces cerevisiae; Salicylamides | 1982 |
Formation of (4R)- and (4S)-4-hydroxyochratoxin A and 10-hydroxyochratoxin A from Ochratoxin A by rabbit liver microsomes.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Hydroxylation; Magnetic Resonance Spectroscopy; Male; Metyrapone; Microsomes, Liver; NADP; Ochratoxins; Phenobarbital; Rabbits | 1983 |
6. Steroid metabolism in neuroendocrine structures. Specific and nonspecific components in the oxidative metabolism of estradiol by the male rat brain in vitro.
Topics: Animals; Biotransformation; Brain; Carbon Monoxide; Estradiol; Kinetics; Male; Microsomes; NAD; NADP; Oxidation-Reduction; Rats; Tritium | 1983 |
Studies of the human testis. XIII. Properties of nicotinamide adenine dinucleotide (reduced form)-linked 17 alpha-hydroxylation.
Topics: Carbon Monoxide; Humans; Kinetics; Male; Microsomes; NAD; NADP; Oxidation-Reduction; Prostatic Neoplasms; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Testis | 1980 |
Omega- and (omega-1)-hydroxylation of 1-dodecanol by frog liver microsomes.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Dodecanol; Fatty Alcohols; Hydroxylation; Microsomes, Liver; NAD; NADP; Oxygen; Rana catesbeiana | 1981 |
The enzymic reduction and kinetics of oxidation of cytochrome b-245 of neutrophils.
Topics: Animals; Carbon Monoxide; Cattle; Cell Membrane; Cytochrome b Group; Cytochromes; Horses; Humans; Kinetics; NADP; Neutrophils; Oxidation-Reduction; Potentiometry; Spectrophotometry; Swine; Tetradecanoylphorbol Acetate | 1982 |
Aryl hydrocarbon hydroxylase of rat brain mitochondria: properties of, and effect of inhibitors and inducers on, enzyme activity.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Brain; Carbon Monoxide; Enzyme Induction; Enzyme Inhibitors; Guinea Pigs; Kinetics; Mice; Microsomes; Mitochondria; NAD; NADP; Rats; Species Specificity | 1982 |
The influence of carbon tetrachloride metabolism on the carbon tetrachloride-induced activation of rat liver cell phospholipase C activity.
Topics: Animals; Carbon Monoxide; Carbon Tetrachloride; Cell Membrane; Enzyme Activation; Glycerophosphates; Liver; Male; NADP; Phosphatidylcholines; Phospholipases; Protein Binding; Rats; Rats, Inbred Strains; Type C Phospholipases | 1982 |
Mechanism of the inhibitory action of isoniazid on microsomal drug metabolism.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; In Vitro Techniques; Isoniazid; Male; Microsomes, Liver; NADP; Oxygen Consumption; Rats | 1981 |
Enzymic synthesis of juvenile hormone in locust corpora allata: evidence for a microsomal cytochrome P-450 linked methyl farnesoate epoxidase.
Topics: Animals; Carbon Monoxide; Centrifugation, Density Gradient; Corpora Allata; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Female; Grasshoppers; Juvenile Hormones; Methyltransferases; Microsomes; NAD; NADP; Oxygenases | 1981 |
Self-catalysed, O2-independent inactivation of NADPH- or dithionite-reduced microsomal cytochrome P-450 by carbon tetrachloride.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dithionite; Female; In Vitro Techniques; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Rats; Rats, Inbred Strains; Sulfites | 1981 |
Metabolism of all-trans-retinoic acid in hamster liver microsomes: oxidation of 4-hydroxy- to 4-keto-retinoic acid.
Topics: Animals; Carbon Monoxide; Cricetinae; Kinetics; Male; Mesocricetus; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Tretinoin; Vitamin A Deficiency | 1980 |
Liver microsomal metabolism of N-methylcarbazole: a probe for induction, inhibition, and species differences.
Topics: Animals; Benzoflavones; Carbazoles; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Phenobarbital; Proadifen; Rabbits; Rats; Species Specificity | 1980 |
Generation of carbon monoxide during the microsomal metabolism of methylenedioxyphenyl compounds.
Topics: Animals; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dithionite; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Microsomes, Liver; NADP; Piperonyl Butoxide; Rats; Spectrophotometry; Structure-Activity Relationship | 1980 |
Inactivation of purified rat liver cytochrome P-450 by chloramphenicol.
Topics: Amino Acids; Animals; Carbon Monoxide; Chloramphenicol; Cytochrome P-450 Enzyme Inhibitors; In Vitro Techniques; Liver; Male; Mixed Function Oxygenases; NADP; Phenobarbital; Rats | 1980 |
Cytochrome P-450 dependent biotransformation: some recent developments. Introductory remarks: cytochromne P-450 mixed function oxygenases.
Topics: Animals; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme System; Humans; Mixed Function Oxygenases; NADP; Oxidoreductases | 1980 |
The mechanism of chloroform and carbon monoxide formation from carbon tetrachloride by microsomal cytochrome P-450.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Male; Microsomes, Liver; NADP; Protoporphyrins; Rats | 1980 |
Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group. Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Carbon Monoxide; Cerebellum; Citrulline; Cyanides; Heme; NADP; Neurons; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxyhemoglobins; Rats; Sulfhydryl Compounds; Superoxide Dismutase | 1994 |
Small intestinal sulphoxidation of albendazole.
Topics: Albendazole; Animals; Anthelmintics; Biotransformation; Carbon Monoxide; Enzyme Induction; Female; In Vitro Techniques; Intestine, Small; Methimazole; Microsomes; Mixed Function Oxygenases; NADP; Oxidation-Reduction; Rats; Rats, Wistar | 1995 |
Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
Topics: Aldehydes; Arachidonic Acids; Carbon Monoxide; Carcinogens; Coumarins; Cytochrome P-450 Enzyme System; Humans; Hydrogen Peroxide; Lipoxygenase; Lung; Metyrapone; Microsomes; NADP; Nitrosamines; Oxidation-Reduction; Superoxide Dismutase; Temperature | 1995 |
Metabolism of a nitrate ester, dihydropyridine derivative in rabbit hepatic microsomes and cytosol.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytosol; Dihydropyridines; Dithiothreitol; Glutathione; Glutathione Transferase; Male; Miconazole; Microsomes, Liver; NADP; Nitrates; Oxidation-Reduction; Pyridines; Rabbits | 1995 |
Heme oxygenase activity in the adult rat aorta and liver as measured by carbon monoxide formation.
Topics: Animals; Aorta; Carbon Monoxide; Chromatography, Gas; Heme Oxygenase (Decyclizing); In Vitro Techniques; Liver; Male; Mesoporphyrins; Muscle, Smooth, Vascular; NADP; Rats; Rats, Sprague-Dawley | 1995 |
Evidence for a high-affinity enzyme in rat esophageal microsomes which alpha-hydroxylates N'-nitrosonornicotine.
Topics: Animals; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme System; Esophagus; Hydroxylation; Kinetics; Male; Microsomes; Microsomes, Liver; NADP; Nitrosamines; Organ Specificity; Rats; Rats, Inbred F344 | 1994 |
Microbial transformations of steroids--VIII. Transformation of progesterone by whole cells and microsomes of Aspergillus fumigatus.
Topics: Aspergillus fumigatus; Biotransformation; Carbon Monoxide; Cycloheximide; Cytochrome P-450 Enzyme System; Hydroxyprogesterones; Iodates; Ketoconazole; Microsomes; NADP; Progesterone | 1994 |
Interactions of dihydralazine with cytochromes P4501A: a possible explanation for the appearance of anti-cytochrome P4501A2 autoantibodies.
Topics: Animals; Arylamine N-Acetyltransferase; Autoantibodies; Binding Sites; Biotransformation; Blotting, Western; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dihydralazine; Heme; Iron; Isoenzymes; Light; Male; Microsomes, Liver; NADP; Rats; Rats, Sprague-Dawley | 1994 |
Characterization of recombinant plant cinnamate 4-hydroxylase produced in yeast. Kinetic and spectral properties of the major plant P450 of the phenylpropanoid pathway.
Topics: Base Sequence; Carbon Monoxide; Catalysis; Cloning, Molecular; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Helianthus; Immunoblotting; Kinetics; Microsomes; Mixed Function Oxygenases; Molecular Sequence Data; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Plant Proteins; Polymerase Chain Reaction; Promoter Regions, Genetic; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry, Ultraviolet; Trans-Cinnamate 4-Monooxygenase; Transcription, Genetic | 1994 |
Enzymatic reduction of chromium(VI) by human hepatic microsomes.
Topics: Adult; Carbon Monoxide; Carcinogens, Environmental; Chromium; Female; Glucosephosphate Dehydrogenase; Humans; Male; Metyrapone; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Oxygen; Thallium | 1993 |
Differential role in lipid peroxidation between rat P450 1A1 and P450 1A2.
Topics: Animals; Benzene Derivatives; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Isoenzymes; Kinetics; Lipid Peroxidation; Male; Malondialdehyde; Methylcholanthrene; Microsomes, Liver; NADP; Rabbits; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tetramethylphenylenediamine | 1993 |
Cleavage of 3-phenoxybenzoic acid by chicken microsomal preparations.
Topics: 2,2'-Dipyridyl; Animals; Benzoates; Carbon Monoxide; Chickens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cross-Linking Reagents; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Kidney; Metyrapone; Microsomes; NADP; Oxygen; Phenanthrolines; Piperonyl Butoxide | 1993 |
Glutathione-dependent biotransformation of methyl parathion by mouse liver in vitro.
Topics: Animals; Carbon Monoxide; Formaldehyde; Glutathione; In Vitro Techniques; Liver; Male; Methyl Parathion; Mice; Microsomes, Liver; NADP | 1993 |
Involvement of cytochrome P450 in oxime production in glucosinolate biosynthesis as demonstrated by an in vitro microsomal enzyme system isolated from jasmonic acid-induced seedlings of Sinapis alba L.
Topics: Carbon Monoxide; Cyclopentanes; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Glucosinolates; Kinetics; Light; Microsomes; Mustard Plant; NADP; Oximes; Oxygen; Oxylipins; Plants, Medicinal; Tyrosine | 1995 |
Protein-reactive metabolites of carbamazepine in mouse liver microsomes.
Topics: Animals; Anticonvulsants; Ascorbic Acid; Caffeic Acids; Carbamazepine; Carbon Monoxide; Catechol O-Methyltransferase; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dioxolanes; Enzyme Inhibitors; Epoxide Hydrolases; Female; Glutathione Transferase; Mice; Mice, Inbred Strains; Microsomes, Liver; NAD(P)H Dehydrogenase (Quinone); NADP; Piperonyl Butoxide; Sulfhydryl Compounds; Triazoles | 1996 |
Nitric oxide inhibits aromatase activity: mechanisms of action.
Topics: Androstenedione; Aromatase Inhibitors; Carbon Monoxide; Cells, Cultured; Cysteine; Enzyme Inhibitors; Ethylmaleimide; Female; Gene Expression Regulation, Enzymologic; Granulosa Cells; Humans; Luteal Cells; Mercaptoethanol; Microsomes; NADP; Nitric Oxide; Penicillamine; Placenta; RNA, Messenger; S-Nitroso-N-Acetylpenicillamine; Sulfhydryl Reagents | 1996 |
Functional interactions in cytochrome P450BM3. Fatty acid substrate binding alters electron-transfer properties of the flavoprotein domain.
Topics: Bacterial Proteins; Carbon Monoxide; Catalysis; Cytochrome c Group; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Transport; Escherichia coli; Fatty Acids; Flavoproteins; Heme; Hydroxylation; Lauric Acids; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Binding; Spectrometry, Fluorescence | 1996 |
Cytochrome P450 monooxygenase activity in Haemonchus contortus (Nematoda).
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Haemonchus; Kinetics; Larva; Microsomes; Mixed Function Oxygenases; NADP; Phenobarbital; Piperonyl Butoxide; Sheep; Substrate Specificity | 1997 |
Reductive activation of 1,1-dichloro-1-fluoroethane (HCFC-141b) by phenobarbital- and pyridine-induced rat liver microsomal cytochrome P450.
Topics: Alkenes; Anaerobiosis; Animals; Biotransformation; Carbon Monoxide; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cyclic N-Oxides; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Glutathione; Heme; Male; Microsomes, Liver; NADP; Nitrogen Oxides; Oxidation-Reduction; Phenobarbital; Pyridines; Rats; Rats, Wistar | 1996 |
Menadione-dependent reduction of tertiary amine N-oxide by rat liver cytosol.
Topics: Animals; Arsenites; Carbon Monoxide; Catalase; Cytosol; Dicumarol; Hemin; Hemoglobins; Imipramine; Liver; Male; Myoglobin; NAD; NADP; Oxidation-Reduction; Potassium Cyanide; Rats; Rats, Wistar; Sodium Compounds; Vitamin K | 1997 |
Rat olfactory mucosa displays a high activity in metabolizing methyl tert-butyl ether and other gasoline ethers.
Topics: Air Pollutants; Animals; Antineoplastic Agents; Biotransformation; Carbon Monoxide; Carcinogens; Chromatography, Gas; Coumarins; Ethyl Ethers; Gasoline; Male; Methyl Ethers; Mice; Microsomes, Liver; NADP; Olfactory Mucosa; Rats; Rats, Sprague-Dawley | 1997 |
Rat liver nuclear nifurtimox nitroreductase activity.
Topics: Animals; Biotransformation; Carbon Monoxide; Cell Nucleus; Cytochrome P-450 Enzyme System; Enzyme Activation; Lipid Peroxidation; Liver; Male; NADP; NADPH-Ferrihemoprotein Reductase; Nifurtimox; Nitroreductases; Oxygen; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 1997 |
Potent interaction of histamine and polyamines at microsomal cytochrome P450, nuclei, and chromatin from rat hepatocytes.
Topics: Animals; Binding, Competitive; Carbon Monoxide; Cell Nucleus; Chromatin; Cytochrome P-450 Enzyme System; Histamine; Microsomes, Liver; NADP; Polyamines; Radioligand Assay; Rats; Tritium | 1998 |
Reactions catalyzed by tetrahydrobiopterin-free nitric oxide synthase.
Topics: Amino Acids; Animals; Arginine; Biopterins; Carbon Monoxide; Catalase; Catalysis; Chromatography, Gel; Enzyme Induction; Escherichia coli; Macrophages; Mice; NADP; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Recombinant Proteins; Spectrophotometry, Ultraviolet | 1998 |
Microsome-mediated transformation of O-methylandrocymbine to demecolcine and colchicine.
Topics: Alkaloids; Carbon Monoxide; Chromatography, Thin Layer; Colchicine; Colchicum; Cytochrome P-450 Enzyme System; Demecolcine; Hydrogen-Ion Concentration; Light; Microsomes; NADP; Nitrogen; Oxygen; Plants, Medicinal; Seeds; Solvents | 1998 |
The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding.
Topics: Animals; Arginine; Biopterins; Calmodulin; Carbon Monoxide; Catalytic Domain; Conserved Sequence; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Heme; Mutation; NADP; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Rats; Recombinant Proteins; Spectrophotometry; Structure-Activity Relationship | 1998 |
Carbon monoxide stimulates the apical 70-pS K+ channel of the rat thick ascending limb.
Topics: Animals; Biliverdine; Carbon Monoxide; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase (Decyclizing); Kidney; Lysine; Male; NADP; Patch-Clamp Techniques; Porphyrins; Potassium Channels; Rats; Rats, Sprague-Dawley; RNA | 1999 |
In vitro sulfoxidation of aldicarb by hepatic microsomes of channel catfish, Ictalurus punctatus.
Topics: Aldicarb; Animals; beta-Naphthoflavone; Biotransformation; Blotting, Western; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Ethanol; Ictaluridae; Insecticides; Male; Microsomes, Liver; Muscle, Skeletal; NADP; Oxidation-Reduction; Sulfoxides | 1999 |
Purification and characterization of a benzo[a]pyrene hydroxylase from Pleurotus pulmonarius.
Topics: Benzo(a)pyrene; Benzopyrene Hydroxylase; Carbon Monoxide; Cytochrome P-450 Enzyme System; Fungal Proteins; Kinetics; Microsomes; NADP; Pleurotus; Protein Binding; Spectrophotometry; Substrate Specificity | 1999 |
Secologanin synthase which catalyzes the oxidative cleavage of loganin into secologanin is a cytochrome P450.
Topics: Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Glucosides; Iridoid Glucosides; Iridoids; Magnoliopsida; Microsomes; NADP; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Pyrans; Substrate Specificity | 2000 |
Reduction of hydroxamic acids to the corresponding amides catalyzed by rabbit blood.
Topics: 2-Acetylaminofluorene; Animals; Blood; Carbon Monoxide; Catalase; Erythrocytes; Flavin-Adenine Dinucleotide; Hemoglobins; Hydroxamic Acids; Kinetics; Male; Models, Biological; NADP; Niacinamide; Oxygen; Phenacetin; Rabbits; Rats; Salicylamides; Time Factors | 2000 |
Heme oxygenase activity in term human placenta.
Topics: Amnion; Carbon Monoxide; Chorion; Chorionic Villi; Decidua; Female; Heme; Heme Oxygenase (Decyclizing); Humans; Microsomes; NADP; Placenta; Pregnancy | 2000 |
Spectral studies of tert-butyl isothiocyanate-inactivated P450 2E1.
Topics: Animals; Binding Sites; Carbon Monoxide; Chromatography, Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dithionite; Electron Spin Resonance Spectroscopy; Enzyme Activation; Enzyme Inhibitors; Fomepizole; Heme; Iodobenzenes; Isothiocyanates; NADP; Pyrazoles; Rabbits; Rats; Spectrometry, Mass, Electrospray Ionization | 2001 |
7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures.
Topics: Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Glucosides; Iridoids; Ketoconazole; Magnoliopsida; Metyrapone; Miconazole; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Oxygen Consumption; Pyrans | 2001 |
8-dimethylallylnaringenin 2'-hydroxylase, the crucial cytochrome P450 mono-oxygenase for lavandulylated flavanone formation in Sophora flavescens cultured cells.
Topics: Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme System; Flavanones; Flavonoids; Hydroxylation; Mixed Function Oxygenases; NADP; Sophora | 2001 |
Relaxation of canine gallbladder to nerve stimulation involves adrenergic and non-adrenergic non-cholinergic mechanisms.
Topics: Adrenergic Fibers; Animals; Atropine; Autonomic Nervous System; Carbon Monoxide; Dogs; Electric Stimulation; Female; Gallbladder; Guanethidine; Immunohistochemistry; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; NADP; Neurotransmitter Agents; Nitric Oxide; Parasympathetic Nervous System; Sympathetic Nervous System; Sympatholytics; Vasoactive Intestinal Peptide | 2001 |
Deoxysarpagine hydroxylase--a novel enzyme closing a short side pathway of alkaloid biosynthesis in Rauvolfia.
Topics: Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Indole Alkaloids; Kinetics; Light; NADP; Plant Proteins; Rauwolfia; Secologanin Tryptamine Alkaloids; Temperature | 2002 |
NPAS2: a gas-responsive transcription factor.
Topics: Animals; ARNTL Transcription Factors; Basic Helix-Loop-Helix Transcription Factors; Carbon Monoxide; Circadian Rhythm; Dimerization; DNA; Helix-Loop-Helix Motifs; Heme; Ligands; Myoglobin; NADP; Nerve Tissue Proteins; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Spectrophotometry, Ultraviolet; Transcription Factors | 2002 |
Essay: Amersham Biosciences and Science Prize. PAS domains and metabolic status signaling.
Topics: Amino Acid Motifs; ARNTL Transcription Factors; Awards and Prizes; Basic Helix-Loop-Helix Transcription Factors; Carbohydrate Metabolism; Carbon Monoxide; Catalytic Domain; Circadian Rhythm; DNA; Gene Expression Regulation; Glycogen; Glycogen Synthase; Helix-Loop-Helix Motifs; Insulin; Intracellular Signaling Peptides and Proteins; NADP; Nerve Tissue Proteins; Oxidation-Reduction; Phosphorylation; Protein Biosynthesis; Protein Kinases; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Transcription Factors | 2002 |
Mechanism-based inactivation of cytochromes P450 2E1 and 2E1 T303A by tert-butyl acetylenes: characterization of reactive intermediate adducts to the heme and apoprotein.
Topics: Acetylene; Alkylation; Amino Acid Substitution; Animals; Apoproteins; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Heme; Hydroxylation; Kinetics; NADP; Rabbits; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Substrate Specificity | 2002 |
Circadian rhythms. Carbon monoxide and clocks.
Topics: Animals; ARNTL Transcription Factors; Autonomic Nervous System; Basic Helix-Loop-Helix Transcription Factors; Behavior, Animal; Brain; Carbon Monoxide; Circadian Rhythm; CLOCK Proteins; Diffusion; Dimerization; DNA; Helix-Loop-Helix Motifs; Heme; Heme Oxygenase (Decyclizing); Mice; Models, Genetic; NAD; NADP; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Oxidation-Reduction; Protein Structure, Tertiary; Synaptic Transmission; Trans-Activators; Transcription Factors; Transcription, Genetic | 2002 |
Formation of benzoquinol moiety in cornoside by salidroside mono-oxygenase, a cytochrome P450 enzyme, from Abeliophyllum distichumcell suspension cultures.
Topics: Benzoquinones; Carbon Monoxide; Cells, Cultured; Cyclohexanones; Cytochrome c Group; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Glucosides; Hydrogen-Ion Concentration; Miconazole; Mixed Function Oxygenases; NADP; Oleaceae; Oxygen; Phenols; Reactive Oxygen Species | 2003 |
Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family, from cultured Coptis japonica cells.
Topics: Alcohol Oxidoreductases; Amino Acid Sequence; Amino Acids; Berberine; Berberine Alkaloids; Carbon Monoxide; Cloning, Molecular; Coptis; Cytochrome P-450 Enzyme System; DNA, Complementary; Dose-Response Relationship, Drug; Gene Library; Genetic Vectors; Kinetics; Models, Chemical; Molecular Sequence Data; NADP; Oxygen; Phylogeny; Polymerase Chain Reaction; Recombinant Proteins; RNA; Sequence Analysis, DNA; Time Factors | 2003 |
Substituent effect on the reductive N-dearylation of 3-(indol-1-yl)-1,2-benzisoxazoles by rat liver microsomes.
Topics: Air; Amidines; Animals; Carbon Monoxide; Chemistry Techniques, Analytical; Cytochrome P-450 Enzyme System; Electrons; Indoles; Isoxazoles; Ketoconazole; Microsomes, Liver; Molecular Structure; NADP; Oxazoles; Oxidation-Reduction; Rats; Structure-Activity Relationship | 2003 |
Jasmonate-induced epoxidation of tabersonine by a cytochrome P-450 in hairy root cultures of Catharanthus roseus.
Topics: Acetates; Alkaloids; Carbon Monoxide; Catharanthus; Cyclopentanes; Cytochrome P-450 Enzyme System; Cytochromes c; Enzyme Inhibitors; Epoxy Compounds; Hydrolases; Indole Alkaloids; Indoles; Microsomes; NADP; Oxidation-Reduction; Oxidoreductases; Oxygen; Oxylipins; Plant Roots; Quinolines | 2003 |
THE OXIDATIC ACTIVITY OF HORSERADISH PEROXIDASE. II. PARTICIPATION OF FERROPEROXIDASE.
Topics: Carbon Monoxide; Enzyme Inhibitors; Fumarates; Horseradish Peroxidase; Light; NADP; Naphthoquinones; Oxidation-Reduction; Oxygen; Peroxidases; Plants, Medicinal; Research; Spectrophotometry | 1963 |
A NOTE ON THE METHEMOGLOBIN REDUCTASE ACTIVITY OF RABBIT ERYTHROCYTES.
Topics: Carbon Monoxide; Cytochrome-B(5) Reductase; Edetic Acid; Erythrocytes; Glucose; Glycerophosphates; Hexosephosphates; Manometry; Methemoglobin; NAD; NADP; Oxidation-Reduction; Oxidoreductases; Pharmacology; Quinacrine; Quinine; Rabbits; Research; Spectrophotometry | 1964 |
REDUCTION OF MICROSOMAL CYTOCHROMES BY PYRIDINE NUCLEOTIDES.
Topics: Carbon Monoxide; Cytochromes; Electron Transport; Kinetics; Lipase; Liver; Microsomes; NAD; NADP; Oxidoreductases; Pharmacology; Pyridines; Research; Spectrophotometry; Vitamin K | 1965 |
Cytochrome P450-catalyzed brassinosteroid pathway activation through synthesis of castasterone and brassinolide in Phaseolus vulgaris.
Topics: Brassinosteroids; Carbon Monoxide; Catalysis; Cholestanols; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Inhibitors; Gas Chromatography-Mass Spectrometry; Light; Microsomes; NADP; Oxidation-Reduction; Oxygen; Phaseolus; Phytosterols; Steroids, Heterocyclic | 2004 |
Conversion of the 2,2,6,6-tetramethylpiperidine moiety to a 2,2-dimethylpyrrolidine by cytochrome P450: evidence for a mechanism involving nitroxide radicals and heme iron.
Topics: Aerobiosis; Anaerobiosis; Carbon Monoxide; Cyclic N-Oxides; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Deferoxamine; Free Radicals; Heme; Hemin; Humans; Iron; Iron Chelating Agents; Microsomes, Liver; NADP; Nitrogen Oxides; Oxygen Isotopes; Piperidones; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Triacetoneamine-N-Oxyl | 2004 |
Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
Topics: Bacillus megaterium; Bacillus subtilis; Bacterial Proteins; Carbon Monoxide; Cloning, Molecular; Coenzymes; Cytochrome P-450 Enzyme System; Fatty Acids; Flavoproteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Heme; Hydroxylation; Kinetics; Mixed Function Oxygenases; Myristic Acid; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Binding; Sequence Alignment; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2004 |
Carbon monoxide improves cardiac energetics and safeguards the heart during reperfusion after cardiopulmonary bypass in pigs.
Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Apoptosis; Carbon Monoxide; Cardiopulmonary Bypass; Cardiotonic Agents; Edema; Electric Countershock; Energy Metabolism; Female; Guanosine Triphosphate; Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; NAD; NADP; Oxidation-Reduction; Sus scrofa | 2004 |
Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel.
Topics: Animals; Carbon Monoxide; Carotid Body; Cell Hypoxia; Cell Line; Heme; Heme Oxygenase (Decyclizing); Humans; Immunoprecipitation; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; NADP; Oxygen; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Rats; RNA Interference; RNA, Small Interfering; Transfection | 2004 |
Cell biology. Oxygen sensing: it's a gas!
Topics: Animals; Carbon Monoxide; Carotid Body; Cell Hypoxia; Cell Membrane; Cells, Cultured; Heme; Heme Oxygenase (Decyclizing); Hemeproteins; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Mitochondria; NADP; NADPH Oxidases; Oxidation-Reduction; Oxygen; Potassium Channels, Calcium-Activated; Proteomics; RNA, Small Interfering; Signal Transduction | 2004 |
Methoxy-resorufin ether as an electrochemically active biological probe for cytochrome P450 O-demethylation.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Drosophila melanogaster; Electrochemistry; Methylation; Microsomes; Molecular Structure; NADP; Oxazines; Spectrometry, Fluorescence; Substrate Specificity; Time Factors | 2006 |
Aerobic 2- and 4-nitroreduction of CB 1954 by human liver.
Topics: Antineoplastic Agents; Aziridines; Carbon Monoxide; Chromatography, High Pressure Liquid; Clinical Trials, Phase I as Topic; Cytosol; Cytotoxins; Dicumarol; Escherichia coli; Humans; Hydroxylamines; Hypoxia; Liver; Mass Spectrometry; Microsomes, Liver; NAD; NADP; Nitroreductases; Prodrugs | 2005 |
Inactivation of CYP2A6 and CYP2A13 during nicotine metabolism.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Escherichia coli; Half-Life; Heme; Humans; Kinetics; Mixed Function Oxygenases; NADP; Nicotine; Nicotinic Agonists; Rats; Substrate Specificity | 2006 |
BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Cell Line; Chromatography, Gel; Chromatography, High Pressure Liquid; Dimerization; Enzyme Activation; Enzyme Inhibitors; Heme; Humans; Imidazoles; Iron; Kinetics; Mice; NADP; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxygen; Pyridines; Time Factors; Tritium | 2008 |
Isoporphyrin intermediate in heme oxygenase catalysis. Oxidation of alpha-meso-phenylheme.
Topics: Biliverdine; Carbon Monoxide; Catalysis; Chromatography, High Pressure Liquid; Heme; Heme Oxygenase-1; Humans; Hydrogen Peroxide; Iron; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Superoxides | 2008 |
Quantitating carbon monoxide production from heme by vascular plant preparations in vitro.
Topics: Carbon Monoxide; Chloroplasts; Chromatography, Gas; Heme; NADP; Oxygen; Plant Structures; Plants; Solanum tuberosum; Spinacia oleracea | 2011 |
Reciprocal regulation of Ca²+-activated outward K+ channels of Pyrus pyrifolia pollen by heme and carbon monoxide.
Topics: Carbon Monoxide; Germination; Heme; Ion Channel Gating; NADP; Pollen; Pollen Tube; Potassium Channels, Calcium-Activated; Protoplasts; Pyrus | 2011 |
Efficient bioelectronic actuation of the natural catalytic pathway of human metabolic cytochrome P450s.
Topics: Biocatalysis; Carbon Monoxide; Cytochrome P-450 Enzyme System; Electrochemistry; Electrodes; Electron Transport; Electrons; Humans; Kinetics; Microsomes; NADP; NADPH-Ferrihemoprotein Reductase | 2011 |
Mechanism-based inactivation of cytochrome P450 2B6 by methadone through destruction of prosthetic heme.
Topics: Analgesics, Opioid; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B6; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heme; Humans; Kinetics; Methadone; NADP; Oxidoreductases, N-Demethylating; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2012 |
NADP-specific electron-bifurcating [FeFe]-hydrogenase in a functional complex with formate dehydrogenase in Clostridium autoethanogenum grown on CO.
Topics: Bacterial Proteins; Bacteriological Techniques; Carbon Monoxide; Clostridium; Electron Transport; Formate Dehydrogenases; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Hydrogenase; Iron; Iron-Sulfur Proteins; Molecular Sequence Data; NADP | 2013 |
Reconstruction of an acetogenic 2,3-butanediol pathway involving a novel NADPH-dependent primary-secondary alcohol dehydrogenase.
Topics: Acetoin; Acetolactate Synthase; Alcohol Oxidoreductases; Anaerobiosis; Butylene Glycols; Carbon Monoxide; Carboxy-Lyases; Cloning, Molecular; Clostridium; Escherichia coli; Gene Expression; Kinetics; Metabolic Networks and Pathways; NADP; Substrate Specificity | 2014 |
Cross-talk between CD38 and TTP Is Essential for Resolution of Inflammation during Microbial Sepsis.
Topics: Adenosine Diphosphate Ribose; ADP-ribosyl Cyclase 1; Animals; Autophagosomes; Calcium; Carbon Monoxide; Cell Line; Disease Models, Animal; Humans; Inflammation; Lipopolysaccharides; Macrophages; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NAD; NADP; Ras Homolog Enriched in Brain Protein; RNA, Small Interfering; Sepsis; Sirtuin 1; TOR Serine-Threonine Kinases; Tristetraprolin | 2020 |