carbon monoxide has been researched along with metyrapone in 77 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 60 (77.92) | 18.7374 |
| 1990's | 13 (16.88) | 18.2507 |
| 2000's | 4 (5.19) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kahl, GF; Kahl, R; Kumaki, K; Nebert, DW | 1 |
| Bloemendal, H; Goos, CM; Henderson, PT; Vermorken, AJ | 1 |
| Feller, DR; Fowble, JW; Miller, DD; Son, OS | 1 |
| Estabrook, RW; Werringloer, J | 1 |
| Okuda, K; Ruf, HH; Ullrich, V | 1 |
| Grudin, R; Moldèus, P; Orrenius, S; Vadi, H | 1 |
| Hales, CA; Miller, MA | 1 |
| Dodia, C; Fisher, AB; Itakura, N; Thurman, RG | 1 |
| Fishman, J; Hahn, EF; Norton, BI | 1 |
| Ichihara, S; Sawahata, T; Watabe, T | 1 |
| McGowan, C; Sylvester, JT | 1 |
| Agosin, M; Capdevila, J; Naquira, C; Paulin, J | 1 |
| Berg, A; Carlstrom, K; Gustafsson, JA; Ingelman-Sundberg, M | 1 |
| Burke, MD; Prough, RA | 1 |
| Cinti, DL; Feinstein, MB | 1 |
| Canick, JA; Ryan, KJ | 1 |
| Cooper, DY; Rosenthal, O; Schleyer, H; Thomas, JH; Vars, HM | 1 |
| Helia, O; Pauliková, I | 1 |
| Guo, Z; Hong, JY; Ning, SM; Smith, TJ; Thomas, PE; Yang, CS | 1 |
| Fantel, AG; Juchau, MR; Lee, QH | 1 |
| Adeagbo, AS; Breen, CA; Coceani, F; Cutz, E; Lees, JG; Olley, PM | 1 |
| Adams, SP; Notides, AC | 1 |
| Cederbaum, AI; Krikun, G | 1 |
| Hayashi, S; Ishikawa, T; Murakami, K; Noshiro, M; Okuda, K; Shimosato, T | 1 |
| Bergman, A; Brandt, I; Lund, BO | 1 |
| Freeman, JJ; Hayes, EP | 1 |
| Diehl, H; Schröder, U | 1 |
| Kiguchi, T; Kobayashi, Y; Ninomiya, I; Nishiguchi, Y; Watanabe, F | 1 |
| Smith, AG; Stewart, FP | 1 |
| Wickramasinghe, SN | 1 |
| Inoue, T; Kishi, T; Niwaguchi, T; Suzuki, S; Yasuda, T | 1 |
| Delaissé, JM; Nyns, EJ | 1 |
| Hellmer, KH; Tabarelli, S; Uehleke, H | 1 |
| Tabarelli, S; Uehleke, H | 1 |
| Bergheim, P; Netter, KJ; Rathgen, GH | 1 |
| Hellmer, KH; Tabarelli-Poplawski, S; Uehleke, H | 1 |
| DeLuca, HF; Ghazarian, JG; Jefcoate, CR; Knutson, JC; Orme-Johnson, WH | 1 |
| Davis, TK; Sloane, NH | 1 |
| Rösen, P; Stier, A | 1 |
| Bell, JJ; Harding, BW; Whysner, JA; Wilson, LD | 1 |
| Estabrook, RW; Franklin, MR; Hildebrandt, AG | 1 |
| Siiteri, PK; Thompson, EA | 1 |
| Illing, HP; Netter, KJ | 1 |
| Harding, BW; Oldham, SB; Wilson, LD | 1 |
| Estabrook, RW; Franklin, MR; Hildebrandt, AG; Roots, I | 1 |
| Fazekas, AG; Lanthier, A; Leblanc, H; Lehoux, JG; Sandor, T | 1 |
| Leblanc, H; Lehoux, JG; Sandor, T | 1 |
| Athanassopoulos, S; Hellmer, KH; Murray, RE; Reiner, O; Uehleke, H | 1 |
| Frommer, U; Orrenius, S; Staudinger, H; Ullrich, V | 1 |
| Hildebrandt, AG | 1 |
| Furukawa, T; Shigematsu, A; Takahashi, S | 1 |
| Lunardi, J; Satre, M; Vignais, PV | 1 |
| Hewick, DS; Young, CK | 1 |
| Hüthwohl, B; Jonen, HG; Kahl, GF; Kahl, R | 1 |
| Casida, JE; Engel, JL; Matthews, HB; Skrinjarić-Spoljar, M | 1 |
| Estabrook, RW; Hildebrandt, AG; Leibman, KC | 1 |
| Coceani, F; Hamilton, NC; Labuc, J; Olley, PM | 1 |
| Walsh, C; Waxman, DJ | 1 |
| Aasen, AJ; Hansen, CE; Pedersen, JI; Støren, O; Størmer, FC | 1 |
| Brittain, T; Costa, AK; Ivanetich, KM | 1 |
| Porter, WR; Trager, WF; Wheeler, C | 1 |
| Aasen, AJ; Hansen, CE; Hvistendahl, G; Pedersen, JI; Størmer, FC | 1 |
| Hollenberg, PF; Koop, DR | 1 |
| Shertzer, HG; Tucker, LD | 1 |
| Smith, TJ; Stoner, GD; Yang, CS | 1 |
| Myers, CR; Pratt, PF | 1 |
| Berger, BJ; Fairlamb, AH | 1 |
| Akhtar, MH; Mahadevan, S; Russell, F | 1 |
| Brien, JF; Liu, Z; Marks, GS; McLaughlin, BE; Nakatsu, K | 1 |
| Graham, MA; Hemingway, SA; Riley, RJ; Workman, P | 1 |
| Cox, HH; Doddema, HJ; Faber, BW; Harder, W; Radhoe, H; Van Heiningen, WN | 1 |
| Hirobe, M; Mashino, T; Ohe, T | 1 |
| Besse, P; Combourieu, B; Delort, AM; Poupin, P; Sancelme, M; Truffaut, N; Veschambre, H | 1 |
| Andreesen, JR; Schräder, T; Schuffenhauer, G; Sielaff, B | 1 |
| Iio, R; Inoue, K; Katano, N; Yamamoto, H | 1 |
| Archakov, AI; Karuzina, II; Lisitsa, AV; Petushkova, NA; Zgoda, VG | 1 |
| Bistolas, N; Christenson, A; Jung, C; Ruzgas, T; Scheller, FW; Wollenberger, U | 1 |
2 review(s) available for carbon monoxide and metyrapone
| Article | Year |
|---|---|
The binding of metyrapone to cytochrome P-450 and its inhibitory action on microsomal hepatic mixed function oxidation reactions.
Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Ethylamines; Hydrogen-Ion Concentration; In Vitro Techniques; Isocitrate Dehydrogenase; Methylation; Metyrapone; Microsomes, Liver; Morphinans; Oxidation-Reduction; Phenobarbital; Proadifen; Pseudomonas; Rats; Spectrum Analysis | 1972 |
[Role of cytochrome P-450 in mixed function oxidation and metabolism of anesthetics].
Topics: Anesthetics; Animals; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Transport; Enzyme Induction; Metyrapone; Microsomes, Liver; Oxidation-Reduction; Proadifen | 1974 |
75 other study(ies) available for carbon monoxide and metyrapone
| Article | Year |
|---|---|
Association of the Ah locus with specific changes in metyrapone and ethylisocyanide binding to mouse liver microsomes.
Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Cytochromes; Dithionite; Enzyme Induction; Genes, Dominant; Hydrogen-Ion Concentration; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; Mutation; Oxygenases; Phenobarbital; Protein Binding; Protein Conformation; Spectrophotometry | 1976 |
Hydroxylation of dehydroepiandrosterone in human scalp hair follicles.
Topics: Androstenediols; Autoradiography; Carbon Monoxide; Dehydroepiandrosterone; Hair; Humans; Hydroxylation; Metyrapone; Mixed Function Oxygenases; NADP; Scalp; Subcellular Fractions | 1979 |
2-Acetylaminofluorene metabolism in rat liver microsomes: formation of 9-hydroxy-2-acetylaminofluorene and effect of hepatic enzyme modifiers.
Topics: 2-Acetylaminofluorene; Animals; Biotransformation; Carbon Monoxide; Hydroxylation; In Vitro Techniques; Liver; Male; Metyrapone; Microsomes, Liver; NADP; Rats | 1979 |
Heterogeneity of liver microsomal cytochrome P-450: the spectral characterization of reactants with reduced cytochrome P-450.
Topics: Animals; Benzphetamine; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Ferricyanides; Mathematics; Metyrapone; Microsomes, Liver; Nitriles; Oxidation-Reduction; Protein Binding; Protein Conformation; Rats; Spectrophotometry | 1975 |
Spectral evidence for a liver mitochondrial cytochrome P450 involved in bile acid metabolism.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Metyrapone; Microsomes, Liver; Mitochondria, Liver; Organophosphorus Compounds; Oxidation-Reduction; Protein Binding; Rats; Spectrophotometry; Sterols | 1977 |
Drug metabolism in isolated rat liver cells.
Topics: Alprenolol; Animals; Biotransformation; Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Fasting; Glucose; Glucuronates; Imipramine; Lactates; Liver; Methods; Metyrapone; NADP; Oxidation-Reduction; Phenobarbital; Proadifen; Protein Binding; Rats; Rotenone; Spectrum Analysis; Temperature; Tritium | 1975 |
Role of cytochrome P-450 in alveolar hypoxic pulmonary vasoconstriction in dogs.
Topics: Angiotensin II; Animals; Blood Pressure; Carbon Monoxide; Cardiac Output; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dogs; Hypoxia; Metyrapone; Prostaglandins F; Pulmonary Artery; Pulmonary Circulation; Vasoconstriction | 1979 |
Relationship between alveolar PO2 and the rate of p-nitroanisole O-demethylation by the cytochrome P-450 pathway in isolated rabbit lungs.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; In Vitro Techniques; Lung; Metyrapone; Microsomes; Mixed Function Oxygenases; Nitroanisole O-Demethylase; Oxidoreductases; Oxygen; Perfusion; Pulmonary Alveoli; Rabbits | 1979 |
Opiate target site N-demethylase enzymes: differences from the liver N-demethylase.
Topics: Animals; Brain; Carbon Monoxide; Carbon Radioisotopes; Metyrapone; Microsomes; Microsomes, Liver; Morphine; Organ Specificity; Oxidoreductases, N-Demethylating; Rats; Subcellular Fractions; Tritium | 1979 |
Hepatic microsomal biotransformation of 1,3,5(10),16-estratetraen-3-o1 to 16,17-epiestriol and estriol via 16 alpha,17 alpha- and 16 beta,17 beta-epoxy-1,3,5(10)-estratrien-3-ols.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Epoxy Compounds; Estrenes; Estriol; Female; Magnetic Resonance Spectroscopy; Mass Spectrometry; Metyrapone; Microsomes, Liver; Proadifen; Rats; Stereoisomerism | 1979 |
The effects of agents that bind to cytochrome P-450 on hypoxic pulmonary vasoconstriction.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Extracorporeal Circulation; Hypoxia; Lung; Metyrapone; Muscle, Smooth; Proadifen; Prostaglandins F; Swine; Vasoconstriction | 1978 |
Cytochrome P-450 and drug metabolism in Trypanosoma cruzi: effects of phenobarbital.
Topics: Aminopyrine; Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Cytochrome P-450 Enzyme System; Metyrapone; Microsomes; Mixed Function Oxygenases; Oxidoreductases, O-Demethylating; Phenobarbital; Proadifen; Ribosomes; Trypanosoma cruzi | 1976 |
Demonstration of a cytochrome P-450-dependent steroid 15beta-hydroxylase in Bacillus megaterium.
Topics: Bacillus megaterium; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Imidazoles; Kinetics; Metyrapone; Multienzyme Complexes; Proadifen; Progesterone; Protein Binding; Steroid Hydroxylases | 1975 |
Some characteristics of hamster liver and lung microsomal aryl hydrocarbon (biphenyl and benzo(a)pyrene) hydroxylation reactions.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Benzopyrenes; Carbon Monoxide; Cricetinae; Cytochrome P-450 Enzyme System; Ethylmorphine-N-Demethylase; Flavonoids; Lung; Male; Mesocricetus; Methylcholanthrene; Metyrapone; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Morphine Derivatives; Naphthalenes; Oxidoreductases, N-Demethylating | 1976 |
Platelet cytochrome P450: a possible role in arachidonate-induced aggregation.
Topics: Arachidonic Acids; Blood Platelets; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Humans; Metyrapone; Microsomes; Peroxides; Platelet Aggregation; Prostaglandins; Protein Binding; Protein Conformation; Spectrophotometry | 1976 |
Cytochrome P-450 and the aromatization of 16alpha-hydroxytestosterone and androstenedione by human placental microsomes.
Topics: Androstenedione; Aromatase; Carbon Monoxide; Cytochrome P-450 Enzyme System; Female; Humans; Hydroxytestosterones; Kinetics; Metyrapone; Microsomes; Placenta; Pregnancy; Spectrophotometry; Testosterone | 1976 |
Comparison of the induction course, biophysical chemical interactions and photochemical action spectra of phenobarbital and 3-methylcholanthrene induce hepatic microsomal P-450.
Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Carbon Monoxide; Codeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexobarbital; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital; Photochemistry; Polycyclic Compounds; Proadifen; Rats; Spectrum Analysis; Time Factors | 1975 |
Rat hepatic microsomal metabolism of oxyprothepine: the role of inhibitors on S-oxygenation.
Topics: Animals; Antimetabolites; Carbon Monoxide; Dibenzothiepins; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Oxidation-Reduction; Proadifen; Rats; Rats, Inbred Strains | 1992 |
Kinetics and enzyme involvement in the metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in microsomes of rat lung and nasal mucosa.
Topics: Animals; Aspirin; Benzoflavones; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Hydroxylation; In Vitro Techniques; Isoenzymes; Lung; Male; Metyrapone; Microsomes; Nasal Mucosa; Nitrosamines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains | 1992 |
Human embryonic cytochrome P450S: phenoxazone ethers as probes for expression of functional isoforms during organogenesis.
Topics: Antibodies, Monoclonal; Benzoflavones; Biotransformation; Carbon Monoxide; Cytochrome P-450 CYP2B1; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Ethers; Humans; Isoenzymes; Metyrapone; Morphogenesis; Orphenadrine; Oxazines; Oxidoreductases; Xenobiotics | 1991 |
Lamb ductus venosus: evidence of a cytochrome P-450 mechanism in its contractile tension.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ductus Arteriosus; Female; Light; Metyrapone; Pregnancy; Sheep; Vasoconstriction; Veins | 1990 |
Reduction of irreversible binding of diethylstilbestrol in hamster renal cortex by inhibitors of cytochrome P-450.
Topics: Animals; Butylated Hydroxytoluene; Carbon Monoxide; Chromatography, High Pressure Liquid; Cricetinae; Cytochrome P-450 Enzyme System; Dicumarol; Dienestrol; Diethylstilbestrol; Isoenzymes; Kidney Cortex; Male; Metyrapone; Microsomes, Liver; Proadifen; Time Factors | 1987 |
Evaluation of microsomal pathways of oxidation of alcohols and hydroxyl radical scavenging agents with carbon monoxide and cobalt protoporphyrin IX.
Topics: Alcohols; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Deferoxamine; Hydrogen Peroxide; Hydroxides; Hydroxyl Radical; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; Oxidation-Reduction; Porphyrins; Proadifen; Protoporphyrins; Rats; Rats, Inbred Strains; Superoxides | 1985 |
Aryl hydrocarbon hydroxylase activity in rat submandibular glands.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Carbon Monoxide; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Metyrapone; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Oxygenases; Proadifen; Rats; Rats, Inbred Strains; Submandibular Gland; Time Factors | 1986 |
Metabolic activation and toxicity of a DDT-metabolite, 3-methylsulphonyl-DDE, in the adrenal zona fasciculata in mice.
Topics: Adrenal Cortex; Animals; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dichlorodiphenyl Dichloroethylene; Epoxide Hydrolases; Epoxy Compounds; Female; Glutathione; Metyrapone; Mice; Mice, Inbred C57BL; Necrosis; Protein Binding; Tissue Distribution | 1988 |
Microsomal metabolism of acetonitrile to cyanide. Effects of acetone and other compounds.
Topics: Acetone; Acetonitriles; Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Ethanol; Female; Metyrapone; Microsomes, Liver; NAD; Proadifen; Proteins; Rats; Rats, Inbred Strains; Time Factors | 1988 |
Substrate specificity of the carbon monoxide-dependent cytochrome P-450 kinetics.
Topics: Animals; Benzoflavones; Carbon Monoxide; Coumarins; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Metyrapone; Microsomes, Liver; NADP; Substrate Specificity; Swine | 1987 |
An alternative metabolic pathway of 11-deoxycorticosterone in bovine adrenal in vitro: evidence for the presence of a pathway of 11-deoxycorticosterone oxidation at 19-position.
Topics: Adrenal Glands; Animals; Carbon Monoxide; Cattle; Cytochrome P-450 Enzyme System; Desoxycorticosterone; In Vitro Techniques; Kinetics; Metyrapone; Oxidation-Reduction; Potassium Cyanide | 1987 |
Metabolism of the "mixed" cytochrome P-450 inducer hexachlorobenzene by rat liver microsomes.
Topics: Acetylcysteine; Aroclors; Carbon Monoxide; Chlorobenzenes; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Ellipticines; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Hexachlorobenzene; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Molecular Weight; NADP; Pentachlorophenol; Phenobarbital; Polychlorinated Dibenzodioxins; Proadifen; Safrole | 1986 |
Observations on the biochemical basis of ethanol metabolism by human macrophages.
Topics: Amitrole; Carbon Monoxide; Catalase; Cell Survival; Cells, Cultured; Ethanol; Humans; Macrophages; Metyrapone; NADP; Proadifen; Pyrazoles | 1986 |
The metabolism of 1-phenyl-2-(N-methyl-N-furfurylamino)propane (furfenorex) in the rat in vivo and in vitro.
Topics: Animals; Appetite Depressants; Biotransformation; Carbon Monoxide; Chromatography, Gas; Chromatography, Thin Layer; Furans; In Vitro Techniques; Male; Metyrapone; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Proadifen; Rats; Rats, Inbred Strains; Spectrophotometry | 1986 |
Detection of cytochrome P-450 in subcellular fractions of Endomycopsislipolytica grown on n-hexadecane.
Topics: Alkanes; Ascomycota; Carbon Monoxide; Cytochrome P-450 Enzyme System; Enzyme Induction; Glucose; Metyrapone; Mixed Function Oxygenases; Oxidation-Reduction; Proadifen; Spectrophotometry; Subcellular Fractions; Ultracentrifugation | 1974 |
Binding of 14 C-carbon tetrachloride to microsomal proteins in vitro and formation of CHC1 3 by reduced liver microsomes.
Topics: Anaerobiosis; Animals; Carbon Isotopes; Carbon Monoxide; Carbon Tetrachloride; Chlorofluorocarbons, Methane; Chloroform; Cystamine; Cytochrome P-450 Enzyme System; Edetic Acid; Ethylmaleimide; Gallic Acid; Glutathione; In Vitro Techniques; Kinetics; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Protein Binding; Proteins; Rabbits; Spectrophotometry | 1973 |
N-hydroxylation of 4,4'-diaminodiphenylsulphone (Dapsone) by liver microsomes, and in dogs and humans.
Topics: Animals; Carbon Monoxide; Dapsone; Dogs; Erythrocytes; Female; Hemoglobins; Humans; Hydrogen-Ion Concentration; Hydroxylation; Male; Methemoglobin; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Phenobarbital; Proteins; Rabbits; Time Factors | 1973 |
Interaction of drugs and steroids with human placental microsomes.
Topics: Acetanilides; Amphetamine; Anaerobiosis; Androgens; Aniline Compounds; Anisoles; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Electron Transport; Female; Glucosephosphate Dehydrogenase; Humans; Kinetics; Methyltransferases; Metyrapone; Microsomes; Mixed Function Oxygenases; Myocardium; NADP; Oxidation-Reduction; Oxidoreductases; Pharmaceutical Preparations; Placenta; Pregnancy; Pregnenolone; Progesterone | 1973 |
Metabolic activation of halothane and its covalent binding to liver endoplasmic proteins in vitro.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Carbon Radioisotopes; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Glutathione; Halothane; In Vitro Techniques; Kidney; Lung; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Proadifen; Protein Binding; Rabbits; Spectrophotometry; Sulfites | 1973 |
Mitochondrial cytochrome p450. A component of chick kidney 25-hydrocholecalciferol-1alpha-hydroxylase.
Topics: Adrenal Glands; Aminoglutethimide; Animals; Antimycin A; Binding, Competitive; Carbon Monoxide; Cattle; Chickens; Cytochrome P-450 Enzyme System; Electron Transport Complex IV; Ferredoxins; Hydroxycholecalciferols; Kidney; Kinetics; Male; Metyrapone; Microsomes; Mitochondria; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Spectrophotometry; Steroid Hydroxylases; Tritium | 1974 |
Hydroxymethylation of the benzene ring. Microsomal hydroxymethylation of benzo(alpha)pyrene to 6-hydroxymethylbenzo(alpha)pyrene.
Topics: Aminoglutethimide; Animals; Benzopyrenes; Butanones; Carbon Monoxide; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Drug Stability; Female; Imidazoles; Methanol; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Temperature; Time Factors; Transferases; Tritium; Ultrasonics | 1974 |
Proceedings: Kinetics of the binding of carbon monoxide and oxygen to microsomal cytochrome P450 and the influence of substrates.
Topics: Animals; Binding Sites; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Halothane; Hexobarbital; In Vitro Techniques; Kinetics; Ligands; Metyrapone; Microsomes, Liver; Oxygen Consumption; Phenobarbital; Photolysis; Rats; Spectrophotometry; Temperature; Tetrachloroethylene; Trichloroethylene | 1974 |
Biosynthesis of adrenal corticosteroids: energy metabolism and the hydroxylases.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Carbon Monoxide; Cattle; Cytochromes; Electron Spin Resonance Spectroscopy; Glycolysis; Humans; In Vitro Techniques; Metyrapone; Mixed Function Oxygenases; Oxidation-Reduction; Spectrum Analysis | 1969 |
Factors influencing the inhibitory effect of carbon monoxide on cytochrome P-450-catalyzed mixed function oxidation reactions.
Topics: Animals; Anisoles; Binding Sites; Carbon Monoxide; Cytochromes; Electron Transport; Electron Transport Complex IV; In Vitro Techniques; Methylation; Metyrapone; Microsomes, Liver; Morphine; Nitroso Compounds; Oxidation-Reduction; Phenobarbital; Rats | 1970 |
The involvement of human placental microsomal cytochrome P-450 in aromatization.
Topics: Aminoglutethimide; Androstenedione; Animals; Binding Sites; Binding, Competitive; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Female; Humans; Kinetics; Metyrapone; Microsomes; Microsomes, Liver; Nandrolone; Placenta; Pregnancy; Proadifen; Protein Binding; Rabbits; Receptors, Cell Surface; Spectrophotometry; Spectrophotometry, Ultraviolet; Steroids; Swine; Tritium | 1974 |
Kinetic experiments on the synergistic effect of NADH on microsomal drug oxidation.
Topics: Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Chloromercuribenzoates; Drug Synergism; Hexobarbital; Male; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; NAD; Nitro Compounds; Oxidation-Reduction; Oxygen Consumption; Pharmaceutical Preparations; Pharmacology; Phenobarbital; Phenols; Proadifen; Pyridines; Rats; Spectrophotometry | 1974 |
Cytochrome P450 and steroid 11beta-hydroxylation in mitochondria from human adrenal cortex.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Antimycin A; Breast Neoplasms; Carbon Monoxide; Cushing Syndrome; Cytochromes; Electron Transport; Humans; Malates; Metyrapone; Mitochondria; Mixed Function Oxygenases; NAD; NADP; Spectrophotometry; Stereoisomerism; Stimulation, Chemical; Succinates | 1968 |
The inhibitory effect of metyrapone on cytochrome P-450-catalyzed mixed-function oxidation reactions as compared to the effect of carbon monoxide.
Topics: Carbon Monoxide; Cytochromes; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction | 1971 |
Studies on the biosynthesis of 18-oxygenated steroids from exogenous corticosterone by domestic duck (Anas platyrhynchos) adrenal gland mitochondria.
Topics: Adrenal Glands; Aldosterone; Aminopterin; Animals; Calcium; Carbon Isotopes; Carbon Monoxide; Chloromercuribenzoates; Corticosterone; Cytochrome P-450 Enzyme System; Ducks; Enzyme Activation; Hydroxycorticosteroids; Kinetics; Magnesium; Male; Metyrapone; Mitochondria; NADP; Potassium; Sodium; Structure-Activity Relationship; Tritium | 1972 |
[Adrenal gland 21-hydroxylase from the domestic duck (Anas platyrhynchos)].
Topics: Adrenal Glands; Animals; Carbon Isotopes; Carbon Monoxide; Chloromercuribenzoates; Cytochrome c Group; Cytochrome P-450 Enzyme System; Ducks; Hydroxyprogesterones; Kinetics; Metyrapone; Microsomes; Mixed Function Oxygenases; NADP; Progesterone; Species Specificity; Spectrophotometry; Structure-Activity Relationship; Temperature | 1972 |
[Formation of chloroform from carbon tetrachloride in liver microsomes, lipid peroxidation and destruction of cytochrome P-450].
Topics: Alcohols; Animals; Carbon Monoxide; Carbon Tetrachloride; Chloroform; Cytochrome P-450 Enzyme System; Desipramine; Disulfiram; Flavonoids; Linoleic Acids; Lipid Metabolism; Male; Metyrapone; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygen; Oxygenases; Piperonyl Butoxide; Rabbits; Rats; Ultraviolet Rays | 1972 |
The monooxygenation of N-heptane by rat liver microsomes.
Topics: Aerobiosis; Alcohols; Alkanes; Animals; Carbon Monoxide; Chromatography, Gas; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Isomerism; Kinetics; Mass Spectrometry; Metyrapone; Microsomes, Liver; Myocardium; NADP; Oxidation-Reduction; Oxygenases; Phenobarbital; Rats; Rats, Inbred Strains; Swine; Vibration | 1972 |
( 3 H)metyrapol as a tool for studies of interactions of deoxycorticosterone with adrenal cortex mitochondria.
Topics: Adrenal Glands; Androstenes; Animals; Binding Sites; Binding, Competitive; Borohydrides; Carbon Monoxide; Cattle; Chemical Phenomena; Chemistry; Desoxycorticosterone; Hydroxylation; Ketosteroids; Kinetics; Metyrapone; Mitochondria; Oxygen Consumption; Sulfites; Tritium | 1972 |
Stereoselective inhibition of steroid 11-beta-hydroxylation in ox and sheep adrenocortical mitochondria: comparison of metyrapone and the enantiomers of 2-(4-aminophenyl)-2-phenethylamine (SKF-12185).
Topics: Adrenal Glands; Aniline Compounds; Animals; Carbon Isotopes; Carbon Monoxide; Cattle; Corticosterone; Cytochrome P-450 Enzyme System; Hydroxylation; In Vitro Techniques; Metyrapone; Mitochondria; Phenethylamines; Sheep; Spectrophotometry; Steroids | 1973 |
Influence of pyridine and some pyridine derivatives on spectral properties of reduced microsomes and on microsomal drug metabolizing activity.
Topics: Aminopyrine N-Demethylase; Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Chemical Phenomena; Chemistry; Coenzymes; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; In Vitro Techniques; Ligands; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Pyridines; Rats; Spectrophotometry, Ultraviolet | 1974 |
Response of hepatic microsomal mixed-function oxidases to various types of insecticide chemical synergists administered to mice.
Topics: Alkynes; Aniline Compounds; Animals; Anisoles; Benzopyrans; Carbamates; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Dimethyl Sulfoxide; Dioxoles; Drug Synergism; Enzyme Induction; Ethers; Hexobarbital; Hydrocarbons, Halogenated; Hydroxylation; In Vitro Techniques; Indoles; Insecticides; Male; Metyrapone; Mice; Microsomes, Liver; Mixed Function Oxygenases; Nitro Compounds; Nitrophenols; Organophosphorus Compounds; Organothiophosphorus Compounds; Oxidoreductases; Pesticide Synergists; Pesticides; Piperonyl Butoxide; Proadifen; Pyrazoles; Rotenone; Sleep; Spectrophotometry; Sulfites; Thiadiazoles; Time Factors | 1971 |
Metyrapone interaction with hepatic microsomal cytochrome P-450 from rats treated with phenobarbital.
Topics: Animals; Carbon Monoxide; Cytochromes; Depression, Chemical; Kinetics; Liver; Male; Metyrapone; Microsomes, Liver; Models, Biological; Oxidation-Reduction; Phenobarbital; Rats; Spectrophotometry; Stimulation, Chemical | 1969 |
Cytochrome P 450-linked monooxygenase: involvement in the lamb ductus arteriosus.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ductus Arteriosus; Female; Guinea Pigs; Indomethacin; Metyrapone; Muscle Contraction; Oxygen; Oxygenases; Photic Stimulation; Pregnancy; Sheep | 1984 |
Phenobarbital-induced rat liver cytochrome P-450. Purification and characterization of two closely related isozymic forms.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Isoenzymes; Male; Metyrapone; Microsomes, Liver; Molecular Weight; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Rats; Rats, Inbred Strains; Spectrophotometry; Substrate Specificity | 1982 |
Formation of (4R)- and (4S)-4-hydroxyochratoxin A and 10-hydroxyochratoxin A from Ochratoxin A by rabbit liver microsomes.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Hydroxylation; Magnetic Resonance Spectroscopy; Male; Metyrapone; Microsomes, Liver; NADP; Ochratoxins; Phenobarbital; Rabbits | 1983 |
Limitations on the metyrapone assay for the major phenobarbital inducible form of cytochrome P-450.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Kinetics; Male; Metyrapone; Microsomes, Liver; Phenobarbital; Rats; Substrate Specificity | 1982 |
Stereochemical aspects of the metabolism of phenprocoumon in rat liver microsomes.
Topics: 4-Hydroxycoumarins; Animals; Biotransformation; Carbon Monoxide; Chemical Phenomena; Chemistry; Hydroxylation; In Vitro Techniques; Metyrapone; Microsomes, Liver; NAD; Phenprocoumon; Proadifen; Rats; Stereoisomerism | 1981 |
Formation of (4R)- and (4S)-4-hydroxyochratoxin A from ochratoxin A by liver microsomes from various species.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Humans; Kinetics; Metyrapone; Microsomes, Liver; Ochratoxins; Rats; Swine | 1981 |
Liver microsomal metabolism of N-methylcarbazole: a probe for induction, inhibition, and species differences.
Topics: Animals; Benzoflavones; Carbazoles; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Phenobarbital; Proadifen; Rabbits; Rats; Species Specificity | 1980 |
Split lung perfusion: a new method to test the effects of chemical agents on pulmonary metabolism.
Topics: Aniline Hydroxylase; Animals; Carbon Monoxide; In Vitro Techniques; Lung; Male; Metyrapone; Mixed Function Oxygenases; Nitroanisole O-Demethylase; Perfusion; Rabbits | 1980 |
Activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in human lung microsomes by cytochromes P450, lipoxygenase, and hydroperoxides.
Topics: Aldehydes; Arachidonic Acids; Carbon Monoxide; Carcinogens; Coumarins; Cytochrome P-450 Enzyme System; Humans; Hydrogen Peroxide; Lipoxygenase; Lung; Metyrapone; Microsomes; NADP; Nitrosamines; Oxidation-Reduction; Superoxide Dismutase; Temperature | 1995 |
Enzymatic reduction of chromium(VI) by human hepatic microsomes.
Topics: Adult; Carbon Monoxide; Carcinogens, Environmental; Chromium; Female; Glucosephosphate Dehydrogenase; Humans; Male; Metyrapone; Microsomes, Liver; Middle Aged; NADP; Oxidation-Reduction; Oxygen; Thallium | 1993 |
Cytochrome P450 in trypanosomatids.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Metyrapone; Microsomes, Liver; Pentamidine; Proadifen; Rats; Subcellular Fractions; Trypanosomatina | 1993 |
Cleavage of 3-phenoxybenzoic acid by chicken microsomal preparations.
Topics: 2,2'-Dipyridyl; Animals; Benzoates; Carbon Monoxide; Chickens; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cross-Linking Reagents; Gas Chromatography-Mass Spectrometry; In Vitro Techniques; Kidney; Metyrapone; Microsomes; NADP; Oxygen; Phenanthrolines; Piperonyl Butoxide | 1993 |
Lack of evidence for the involvement of cytochrome P-450 or other hemoproteins in metabolic activation of glyceryl trinitrate in rabbit aorta.
Topics: Animals; Aorta; Biotransformation; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hemeproteins; Hypoxia; In Vitro Techniques; Male; Metyrapone; Nitric Oxide; Nitroglycerin; Proadifen; Rabbits; Vasodilation | 1993 |
Initial characterization of the major mouse cytochrome P450 enzymes involved in the reductive metabolism of the hypoxic cytotoxin 3-amino-1,2,4-benzotriazine-1,4-di-N-oxide (tirapazamine, SR 4233, WIN 59075).
Topics: Animals; Antineoplastic Agents; Benzoflavones; Carbon Monoxide; Cell Hypoxia; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Male; Metyrapone; Mice; Mice, Inbred BALB C; Microsomes, Liver; Oxidation-Reduction; Oxygen; Tirapazamine; Triazines | 1993 |
Styrene metabolism in Exophiala jeanselmei and involvement of a cytochrome P-450-dependent styrene monooxygenase.
Topics: Air Pollutants; Biodegradation, Environmental; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Exophiala; Metyrapone; Oxygenases; Proadifen; Spectrophotometry; Styrene; Styrenes | 1996 |
Substituent elimination from p-substituted phenols by cytochrome P450. ipso-Substitution by the oxygen atom of the active species.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; In Vitro Techniques; Isoenzymes; Male; Metyrapone; Microsomes, Liver; Oxygen Isotopes; Phenols; Rats; Rats, Wistar | 1997 |
Degradation of morpholine by an environmental Mycobacterium strain involves a cytochrome P-450.
Topics: Acetates; Biodegradation, Environmental; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ethanolamine; Ethylamines; Glycolates; Hydrogen; Industrial Waste; Magnetic Resonance Spectroscopy; Metyrapone; Morpholines; Mycobacterium; Piperidines; Pyrrolidines; Sewage; Succinic Acid | 1998 |
High morpholine degradation rates and formation of cytochrome P450 during growth on different cyclic amines by newly isolated Mycobacterium sp. strain HE5.
Topics: Amines; Biodegradation, Environmental; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethanolamine; Glycolates; Glyoxylates; Hydrogen-Ion Concentration; Metyrapone; Molecular Sequence Data; Morpholines; Nontuberculous Mycobacteria; Piperidines; Pyrrolidines; Soil Microbiology; Spectrophotometry, Ultraviolet; Substrate Specificity; Succinic Acid; Temperature; Time Factors | 2000 |
7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures.
Topics: Carbon Monoxide; Cells, Cultured; Cytochrome P-450 Enzyme Inhibitors; Enzyme Inhibitors; Glucosides; Iridoids; Ketoconazole; Magnoliopsida; Metyrapone; Miconazole; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Oxygen Consumption; Pyrans | 2001 |
Production of carbon monoxide by cytochrome P450 during iron-dependent lipid peroxidation.
Topics: alpha-Tocopherol; Animals; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Cytochrome P-450 Enzyme System; Deferoxamine; Enzyme Induction; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); In Vitro Techniques; Iron; Lipid Peroxidation; Metyrapone; Microsomes, Liver; Phenobarbital; Proadifen; Protoporphyrins; Rabbits; Steroid Hydroxylases | 2002 |
Spectroelectrochemistry of cytochrome P450cam.
Topics: Camphor; Camphor 5-Monooxygenase; Carbon Monoxide; Disulfides; Dithionite; Electrochemistry; Electrodes; Enzyme Inhibitors; Escherichia coli; Gold; Metyrapone; Oxidation-Reduction; Pseudomonas putida; Pyridines; Spectrophotometry, Ultraviolet | 2004 |