carbon monoxide has been researched along with heme in 1210 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 379 (31.32) | 18.7374 |
| 1990's | 191 (15.79) | 18.2507 |
| 2000's | 402 (33.22) | 29.6817 |
| 2010's | 207 (17.11) | 24.3611 |
| 2020's | 31 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Hopfield, JJ; Ogawa, S; Shulman, RG | 1 |
| Yamada, H; Yamazaki, I | 1 |
| Hasegawa, E; Honda, K; Tsuchida, E | 2 |
| Hayashi, Y; Yamada, H; Yamazaki, I | 1 |
| Dill, K; Moon, RB; Richards, JH | 1 |
| Chang, CK; Gibson, QH; Moffat, K; Seybert, DW | 1 |
| Hatano, M; Nozawa, T; Orii, Y; Shimada, H | 1 |
| Bechtel, KC; Bonaventura, C; Bonaventura, J; Dunlap, WM; Johnson, MH; Jue, DL; Moo-Penn, WF; Opella, SJ; Schmidt, DE; Schmidt, RM | 1 |
| Cavallin-Ståhl, E; Jönsson, GI; Lundh, B | 1 |
| Guengerich, FP | 1 |
| Gibson, QH; Sawicki, CA | 1 |
| Guzelian, PS; Swisher, RW | 1 |
| Caughey, WS; O'Toole, MC; Volpe, JA | 1 |
| Nozawa, T; Sauer, K; Vickery, L | 1 |
| Iizuka, T | 2 |
| Anderson, JL; Hartzell, CR; Kuwana, T | 1 |
| Chance, B; Harmon, HJ; Ingledew, WJ; Wikström, KF | 1 |
| Iizuka, T; Orii, Y; Yoshida, S | 1 |
| Chiang, SC; Lauer, LD; Li, NC; Rifkind, JM | 1 |
| Babcock, GT; Palmer, G; Vickery, LE | 1 |
| Brittain, T; Greenwood, C; Springall, J; Thomson, AJ | 1 |
| Gersonde, K; Peisach, J | 1 |
| Orii, Y; Yoshida, S | 1 |
| Ishida, A | 1 |
| Sharrock, M; Yonetani, T | 2 |
| Blasie, JK; Erecińska, M; Wilson, DF | 1 |
| Palmer, G; Vickery, LE; Wharton, DC | 1 |
| Ellfolk, N; Rönnberg, M | 1 |
| Geibel, JF; Ranney, HM; Sharma, VS | 1 |
| Brauman, JI; Collman, JP; Doxsee, KM | 1 |
| Caughey, WS; Houtchens, RA; Makinen, MW | 1 |
| Frauenfelder, H; Gunsalus, IC; Nordlund, T; Sligar, SG | 1 |
| Berger, E; Eaton, JW; Eckman, JR; Engel, RR; Modler, S | 1 |
| Bucci, E; Chu, AH | 1 |
| Berzinis, AP; Traylor, TG | 2 |
| Johnson, JD; Ostrander, CE; Stevenson, DK | 1 |
| Brinigar, WS; Wang, CM | 1 |
| Mincey, T; Traylor, TG | 1 |
| Kassner, RJ; Romberg, RW | 2 |
| Burk, RF; Correia, MA | 1 |
| De Matteis, F; Gibbs, AH; Unseld, A | 1 |
| Cassoly, R | 1 |
| Hooper, AB; Maxwell, PC; Terry, KR | 1 |
| Brown, SB; Thomas, SE | 1 |
| Frauenfelder, H | 1 |
| Alvares, AP; Bernstein, SE; Kappas, A; Sassa, S | 1 |
| Feigelson, P | 1 |
| Bengmark, S; Börjesson, B; Lundh, B; Mercke, C; Simert, G; Vang, J | 1 |
| Holbrook, DJ; Krasny, HC | 1 |
| Hall, PF; Tilley, BE; Watanuki, M | 1 |
| Asakura, T; McCray, JA; Sono, M | 1 |
| Bissell, DM; Guzelian, PS | 2 |
| Binger, C; Olson, JS | 1 |
| Lundh, B; Mercke, C | 1 |
| Lundh, B; Ugander, L | 1 |
| Chang, CK; Traylor, TG | 3 |
| Chang, CK; Dolphin, D | 1 |
| Flickinger, EG; Horne, MK; Rosse, WF; Saltzman, HA | 1 |
| Cavallin-Ståhl, E; Lundh, B | 1 |
| Cavallin-Ståhl, E; Lundh, B; Mercke, C | 5 |
| Stonard, MD | 1 |
| Appleby, CA; Leach, SJ; Minasian, E; Nicola, NA | 1 |
| Gibson, QH; Moffat, K; Seybert, DW | 1 |
| Asakura, T; McCray, JA; Smith, PD; Sono, M | 1 |
| Klatt, P; Mayer, B; Schmidt, K | 1 |
| Bredt, DS; Clark, JE; Hirsch, DJ; Masters, BS; McMillan, K; Snyder, SH | 1 |
| Alben, JO; Gennis, RB; Hill, JJ; Shapleigh, JP | 1 |
| Dawes, TD; Einarsdóttir, O; Fee, JA; Goldbeck, RA; Kliger, DS; O'Connor, DB; Surerus, KK | 1 |
| Fujiwara, T; Fukumori, Y; Yamanaka, T | 1 |
| Daldal, F; Davidson, E; Gray, KA | 1 |
| Shinzawa, K; Tsubaki, M; Yoshikawa, S | 1 |
| Ellefson, M; Engel, RR; Levitt, MD; Medina, A; Schwartz, S; Strocchi, A | 1 |
| Larsen, RW; Morgan, WT; Muhoberac, BB; Nunez, DJ; Ondrias, MR | 1 |
| Blackmore, RS; Gibson, QH; Greenwood, C | 1 |
| Funasaki, N; Iizuka, T; Neya, S; Sato, T; Shiro, Y; Tanaka, N | 1 |
| Bellelli, A; Gibson, QH; Regan, R; Sharma, PK; Vinogradov, SN | 1 |
| Kassner, RJ | 1 |
| Kraut, J; Miller, MA; Smulevich, G; Spiro, TG | 1 |
| Fujiwara, T; Fukumori, Y; Qureshi, MH; Yamanaka, T; Yumoto, I | 1 |
| Chashchin, VL; Lapko, AG; Pikuleva, IA | 1 |
| Ascenzi, P; Coletta, M; Del Gaudio, R; Geraci, G; Mantini, AR; Piscopo, M; Smulevich, G | 1 |
| Cheng, XD; Schoenborn, BP | 1 |
| Brüne, B; Schmidt, KU; Ullrich, V | 1 |
| Bohn, B; Kister, J; Marden, MC; Poyart, C | 1 |
| Blackmore, RS; Carver, TE; Gibson, QH; Krzywda, S; Olson, JS; Ropp, JD; Sligar, SG; Smerdon, SJ; Wilkinson, AJ | 1 |
| Puustinen, A; Wikström, M | 1 |
| Fujii-Kuriyama, Y; Furuya, H; Hatano, M; Iwaizumi, M; Ohba, Y; Sadeque, AJ; Shimizu, T; Sotokawa, H | 1 |
| Edwards, SL; Poulos, TL | 1 |
| Bolgiano, B; Gennis, RB; Ingledew, WJ; Poole, RK; Salerno, JC | 1 |
| Coletta, M; Farnum, MF; Kraut, J; Mauro, JM; Miller, MA; Putnam, LD; Traylor, TG | 1 |
| Anraku, Y; Gennis, RB; Lemieux, L; Nakamura, H; Yamato, I | 1 |
| Blackmore, RS; Gadsby, PM; Greenwood, C; Thomson, AJ | 1 |
| Coletta, M; Kraut, J; Mauro, JM; Miller, MA; Smulevich, G; Traylor, TG | 1 |
| Perutz, MF | 1 |
| Bragg, PD; Withers, HK | 1 |
| Leclerc, L; Marden, MC; Poyart, C | 1 |
| Derewenda, Z; Dodson, G; Emsley, P; Harris, D; Nagai, K; Perutz, M; Renaud, JP; Reynaud, JP | 1 |
| Carlton, RR; Castillo, RO; Hamori, CJ; Kerner, JA; Stevenson, DK; Vreman, HJ | 1 |
| Rodgers, PA; Stevenson, DK; Vreman, HJ | 2 |
| Light, WR; Olson, JS | 2 |
| Beaune, P; Descatoire, V; Labbe, G; Larrey, D; Letteron, P; Pessayre, D | 1 |
| Debrunner, PG; Hendrich, MP | 1 |
| Muhoberac, BB; Steup, MB | 1 |
| Kassner, RJ; Patel, MJ | 1 |
| Adachi, S; Morishima, I; Orii, Y; Shiro, Y; Yano, Y | 1 |
| Poulos, TL; Raag, R | 1 |
| Gale, R; Rodgers, PA; Stevenson, DK; Vreman, HJ | 1 |
| Bondoc, LL; Timkovich, R | 1 |
| Gibson, QH; Hazard, ES; Leclerc, L; Marden, MC | 1 |
| Iben, IE; Keszthelyi, L; Ringe, D; Váró, G | 1 |
| English, AM; Fishel, LA; Kraut, J; Mauro, JM; Smulevich, G; Spiro, TG | 1 |
| Buga, GM; Byrns, RE; Ignarro, LJ; Wood, KS | 1 |
| Ellis, CJ; Engel, RR; Levitt, MD | 1 |
| Cusanovich, MA; Meyer, TE; Tollin, G; Vorkink, WP | 1 |
| Tsuchida, E | 1 |
| Alden, RG; Ondrias, MR | 1 |
| Behere, DV; Goff, HM; Gonzalez-Vergara, E | 1 |
| Dasgupta, S; English, A; Smulevich, G; Spiro, TG | 1 |
| Anraku, Y; Hata-Tanaka, A; Itoh, S; Matsuura, K | 1 |
| Ascenzi, P; Brunori, M; Coletta, M | 1 |
| Kaizu, Y; Kobayashi, H | 1 |
| De Matteis, F; King, LJ; Manno, M | 1 |
| Balny, C; Hooper, AB | 1 |
| Argade, PV; Rousseau, DL | 1 |
| Lavalette, D; Lhoste, JM; Momenteau, M; Tetreau, C | 1 |
| Drummond, GS; Kappas, A; Landaw, SA; Sassa, S | 1 |
| Aojula, HS; Morrison, IG; Wilson, MT | 1 |
| Greschner, S; Pismensky, VF; Ruckpaul, K | 1 |
| Stevenson, DK; Vreman, HJ | 2 |
| Gibson, QH; Hazard, ES; Marden, MC | 1 |
| Gersonde, K; Kerr, E; Parish, DW; Smith, KM; Yu, NT | 1 |
| Shigezane, J | 1 |
| Light, WR; Olson, JS; Palmer, G; Rohlfs, RJ | 1 |
| Carson, SD; Findsen, EW; Friedman, JM; Ondrias, MR; Wells, CA | 1 |
| Itano, HA; Kinuta, M; Matteson, JL | 1 |
| Chang, CK; Thompson, HM; Yu, NT | 1 |
| Engel, RR; Levitt, MD; Milleville, GS | 1 |
| Cowan, BE; Kwong, LK; Posselt, AM; Stevenson, DK; Vreman, HJ | 1 |
| Eaton, WA; Henry, ER; Levitt, M | 1 |
| Light, WR; Olson, JS; Rose, MY; Thompson, RA | 1 |
| Paul, J; Paul, KG; Smith, ML | 1 |
| Jaffe, LS | 1 |
| Tamura, M; Woodrow, GV; Yonetani, T | 1 |
| Kamin, H; Murphy, MJ; Siegel, LM | 1 |
| Engel, RR; Rodkey, FL; Rubenstein, CJ; Umstead, ME | 1 |
| Coon, MJ; van der Hoeven, TA | 1 |
| Kikuchi, G; Yoshida, T | 1 |
| Hino, S; Ishida, A | 1 |
| King, TE; Takemori, S; Yong, FC | 1 |
| Asakura, T; Yonetani, T | 1 |
| Ishidate, K; Kawaguchi, K; Tagawa, K | 2 |
| King, TE; Yong, FC | 4 |
| Hagihara, B; Ishidate, K; Kawaguchi, K; Tagawa, K | 1 |
| King, TE; Myer, YP | 1 |
| Miyake, Y; Mori, K; Yamano, T | 1 |
| Hill, HA; Röder, A; Williams, RJ | 1 |
| Asakura, T; Drott, HR; Yonetani, T | 1 |
| Ohishi, S; Yamazaki, H; Yamazaki, I | 1 |
| Tyuma, I | 1 |
| Antonini, E; Brunori, M | 2 |
| Ogunmola, GB; Wohlrab, H | 1 |
| Blumberg, WE; Peisach, J; Rachmilewitz, EA | 1 |
| Hamaguchi, H; Isomoto, A; Miyake, Y; Nakajima, H | 1 |
| Tsudzuki, T; Wilson, DF | 1 |
| Griffin, B; Peterson, JA | 1 |
| Caughey, WS | 1 |
| Marler, HR; Shakespeare, PG | 1 |
| Appleby, CA; Wittenberg, BA; Wittenberg, JB | 1 |
| Brocklehurst, ES; Lindsay, JG; Wilson, DF | 1 |
| Leigh, JS; Wilson, DF | 3 |
| Hultquist, DE; Passon, PG; Reed, DW | 1 |
| Odajima, T; Yamazaki, I | 1 |
| Iizuka, T; Orii, Y | 1 |
| Chapman, SS; Engel, RR; Matsen, JM; Schwartz, S | 1 |
| Erickson, RH; Hooper, AB; Terry, KR | 1 |
| Cusanovich, MA; Gibson, QH | 1 |
| Asakura, T; Tamura, M; Yonetani, T | 2 |
| Gibson, QH; Gudat, JC; Wharton, DC | 1 |
| Cheah, KS | 2 |
| Gnarra, DJ; Green, D; Honig, GR; Mason, RG; Maurer, HS; Shamsuddin, M; Vida, LN | 1 |
| Momenteau, M | 1 |
| Beetlestone, JG; Heidner, EJ; Ho, C; Ladner, JE; Perutz, MF; Slade, EF | 1 |
| King, TE; Leigh, JS; Owen, CS; Wilson, DF | 1 |
| Brunori, M; Dupré, S; Greenwood, C; Wilson, MT | 1 |
| Chen, C; Lin, CC | 1 |
| Nicholas, DJ; Prabhakararao, K | 1 |
| Marver, HS; Schmid, R; Tenhunen, R | 1 |
| Kumaoka, H; Yoshida, Y | 1 |
| Nebert, DW | 1 |
| Coon, MJ; Heidema, J; Lu, AY; Strobel, HW | 1 |
| Alvares, AP; Kappas, A; Mitani, F; Sassa, S | 1 |
| Jacobson, M; Kuntzman, R; Levin, W | 1 |
| Cooper, DY; Marver, H; Pimstone, NR; Schmid, R; Tenhunen, R; Trager, WF | 1 |
| Anderson, NM; Antonini, E; Bonaventura, C; Bonaventura, J; Brunori, M; Chiancone, E; Spagnuolo, C | 1 |
| Berk, PD; Blaschke, TF; Collison, HA; Rodkey, FL; Scharschmidt, BF; Waggoner, JG | 1 |
| Peisach, J; Stern, JO | 1 |
| Makino, R; Yamazaki, I | 1 |
| Antonini, E; Bonaventura, C; Bonaventura, J; Brunori, M; Giardina, B; Wyman, J | 1 |
| Robinson, SH | 1 |
| Pimstone, NR | 1 |
| Coburn, RF | 4 |
| Bensinger, TA; Gillette, PN | 1 |
| Cavallin-Stahl, E; Johansson, MB; Lundh, B; Mercke, C | 1 |
| Mayer, A; Ogawa, S; Shulman, RG | 1 |
| Amiconi, G; Antonini, E; Brunori, M; Formaneck, H; Huber, R | 1 |
| Edelstein, SJ; Thomas, JO | 1 |
| Ho, C; Lindstrom, TR | 1 |
| Gibson, QH | 1 |
| Hager, LP; Hollenberg, PF | 1 |
| Bannai, S; Nakamura, T; Sugita, Y | 1 |
| Mannering, GJ; Shoeman, DW; Vane, FM | 1 |
| Anders, MW; Maines, MD | 2 |
| Brubaker, PE; Klein, R; Lucier, GW; Matthews, HB; McDaniel, OS | 1 |
| Jones, P; Prudhoe, K; Robson, T | 1 |
| Brault, D; Rougee, M | 1 |
| Beeley, JA; Harvey, W | 1 |
| Asakura, T; Chance, B; Hagihara, B; Oshino, N; Oshino, R; Takio, K | 1 |
| Berk, PD; Blaschke, TF; Collison, HA; Rodkey, FL; Waggoner, JG | 1 |
| Coburn, RF; Delivoria-Papadopoulos, M; Forster, RE | 1 |
| Schacter, BA; Waterman, MR | 1 |
| James, BR; Stynes, DV | 1 |
| Lindahl, J | 4 |
| Flatmark, T; Silsand, T; Terland, O | 1 |
| Roberts, RJ; Waters, LR | 1 |
| Ho, C; Johnson, ME | 1 |
| Ben-Hayyim, G; Schejter, A | 1 |
| Anders, MW; Maines, MD; Muller-Eberhard, U | 1 |
| Gunsalus, IC; Yu, C | 1 |
| Beard, RR | 1 |
| Nichol, AW | 2 |
| Cusanovich, MA; Kamen, MD; Tedro, SM | 1 |
| Sjöstrand, T | 1 |
| Appleby, CA | 1 |
| Kellett, GL; Schachman, HK | 1 |
| Winchell, HS | 2 |
| Lynch, SR; Moede, AL | 1 |
| Gibson, QH; Olson, JS | 2 |
| Spiro, TG; Strekas, TC | 1 |
| Landaw, SA | 3 |
| Imamura, T; Riggs, A | 1 |
| Kaminsky, LS; King, TE; Yong, FC | 1 |
| Hermans, J; Shen, LL | 1 |
| Charache, S; Ho, C; Lehmann, H; Lindstrom, TR; Norén, IB | 1 |
| Blanck, J; Jung, F; Ruckpaul, K; Scheler, W | 1 |
| Erickson, RH; Hooper, AB | 1 |
| Gibson, QH; Jenkins, T; Nagel, RL | 1 |
| Bensinger, TA; Conrad, ME; Mahmood, L; Maisels, MJ; McCurdy, PR | 1 |
| Reiner, O; Uehleke, H | 1 |
| Goldkorn, T; Schejter, A; Sokolovsky, M | 1 |
| Feigelson, P; Koike, K | 1 |
| Maruyama, K; Yagi, T | 1 |
| Klotz, IM; Swaney, JB | 1 |
| Alvares, A; Conney, AH; Kuntzman, R; Levin, W | 1 |
| Alvares, AP; Kuntzman, R; Levin, W | 2 |
| Kilmartin, JV; Rossi-Bernardi, L | 1 |
| Bausserman, LL; Nebert, DW | 1 |
| Reed, T | 1 |
| White, P | 1 |
| Drabkin, DL | 1 |
| Antonini, E; Phelps, C | 1 |
| Noble, RW | 2 |
| Kay, CM; Schobaum, GR; Willick, GE | 1 |
| Amiconi, G; Antonini, E; Brunori, M; Phelps, C | 1 |
| Degn, H; Mochan, E | 1 |
| Caughey, W; McCoy, S | 1 |
| Allis, JW; Steinhardt, J | 1 |
| Callahan, EW; Landaw, SA; Schmid, R | 1 |
| King, TE; Mason, HS; Oldham, S; Yong, FC | 1 |
| Chance, B; Rumen, NM | 1 |
| Landaw, SA; Winchell, HS | 2 |
| Jacob, HS; Winterhalter, KH | 1 |
| Gibson, QH; Noble, RW; Parkhurst, LJ | 1 |
| Blakemore, WS; Kenepp, DL; Wallace, HW | 1 |
| Chang, Y; Clezy, PS; Morell, DB; Nichol, AW | 1 |
| Smith, RP | 1 |
| Geraci, G; Gibson, QH; Parkhurst, LJ | 1 |
| Edwards, ML; Gibson, J; Morita, S | 1 |
| Hill, RJ; Macleod, RM | 1 |
| Bernstein, SE; Landaw, SA; Russell, ES | 1 |
| Hultquist, DE; Morrison, M; Reed, DW | 1 |
| Gutterman, LA; Logue, GL; Rosse, WF; Saltzman, HA; Smith, WT | 1 |
| Grizzuti, K; Muller-Eberhard, U | 1 |
| Banerjee, R; Cassoly, R | 1 |
| Singh, J; Wasserman, AR | 1 |
| Banerjee, R; Douzou, P; Lombard, A | 1 |
| Bucci, E; Fronticelli, C; Ragatz, B | 1 |
| Feigelson, P; Maeno, H | 1 |
| Asada, K; Bandurski, RS; Tamura, G | 1 |
| Blumberg, WE; Peisach, J; Wittenberg, BA; Wittenberg, JB | 1 |
| Amiconi, G; Antonini, E; Winterhalter, KH | 1 |
| Bretscher, PA | 1 |
| Hendrickson, WA; Love, WE; Murray, GC | 1 |
| Imai, Y; Sato, R | 1 |
| Alben, JO; Caughey, WS | 1 |
| Mok, TC; Moss, FJ; Rickard, PA | 1 |
| Geraci, G; Li, TK | 1 |
| Kuntzman, R; Levin, W | 1 |
| Tamai, A; Yasuda, T; Yoneyama, Y; Yoshikawa, H | 1 |
| Gonser, U; Grant, RW | 1 |
| Stotz, E; Vanderkool, G | 1 |
| Coburn, RF; Kahn, SB; White, P; Williams, WJ | 1 |
| Deranleau, DA; Winterhalter, KH | 1 |
| Clark-Walker, GD; Lascelles, J; Rittenberg, B | 1 |
| Hayaishi, O; Yamamoto, S | 1 |
| Coburn, RF; Goldwein, MI; Rother, ML; Shafer, BC; White, P; Williams, WJ | 1 |
| Riggs, A; Sullivan, B | 1 |
| Bickar, D; Bonaventura, C; Bonaventura, J | 1 |
| Foote, N; Greenwood, C; Peterson, J; Thomson, AJ | 1 |
| Kawabe, H; Sugiura, Y; Suzuki, T; Tanaka, H; Watanabe, K | 1 |
| Fujii, K; Yamanaka, T | 1 |
| Ellfolk, N; Osterlund, K; Rönnberg, M | 1 |
| Barber, D; Greenwood, C; Johnson, MK; Thomson, AJ; Walsh, TA | 1 |
| Alben, JO; Altschuld, RA; Fiamingo, FG; Moh, PP | 1 |
| Cantoni, L; De Matteis, F; Gibbs, AH | 1 |
| Gogotov, IN; Korsunskiĭ, OF; Laurinavichene, TV; Smolygina, LD | 1 |
| Krueger, RJ; Siegel, LM | 1 |
| Figlovsky, VA; Grigorjev, VA; Sharonov, YA; Sharonova, NA | 1 |
| Janick, PA; Siegel, LM | 1 |
| Christner, JA; Janick, PA; Münck, E; Siegel, LM | 1 |
| Azzi, A; Corbley, MJ | 1 |
| Anraku, Y; Kita, K; Konishi, K | 1 |
| Docherty, JC; Firneisz, GD; Schacter, BA | 1 |
| Lerner, R; Lindahl, J; Werner, B | 1 |
| Groome, LJ; Groome, SD | 1 |
| Lavalette, D; Lhoste, JM; Mispelter, J; Momenteau, M; Tetreau, C | 1 |
| Satterlee, JD | 1 |
| Antonetti, A; Astier, R; Lecarpentier, Y; Martin, JL; Migus, A; Poyart, C | 1 |
| Hall, PF; Nakajin, S | 1 |
| Kerr, EA; Mackin, HC; Yu, NT | 1 |
| Chang, CK; Kerr, EA; Ward, B; Yu, NT | 1 |
| Simone, SM | 1 |
| Cowan, BE; Kwong, LK; Stevenson, DK; Vreman, HJ | 1 |
| Chang, CK; Ebina, S; Ward, B | 1 |
| Hemler, ME; Lands, WE | 1 |
| Kikuchi, G; Noguchi, M; Yoshida, T | 2 |
| Paul, J; Paul, KG; Rosén, A; Smith, ML | 1 |
| Hatchikian, EC; Zeikus, JG | 1 |
| Cedel, TE; Ho, C; Mims, MP; Miura, S; Olson, JS; Russu, IM | 1 |
| Andersson, KK; Balny, C; Debey, P; Hooper, AB | 1 |
| Cohen, RS; Johnson, JD; Ostrander, CR; Stevenson, DK | 1 |
| Beychok, S; Leutzinger, Y | 1 |
| Basolo, F; Hoffman, BM; Jones, RD; Rose, EJ; Swartz, JC; Venkatasubramanian, PN | 1 |
| Traylor, PS; Traylor, TG | 1 |
| Castro, JA; de Toranzo, EG; Fernández, G; Villarruel, MC | 1 |
| Bond, JH; Levine, AS; Levitt, MD; Prentiss, RA | 1 |
| Andersson, KK; Hooper, AB; Kent, TA; Lipscomb, JD; Münck, E | 1 |
| Iizuka, T; Ishimura, Y; Nishide, H; Sekine, M; Tsuchida, E; Yuasa, M | 1 |
| Abe, K; Makino, N; Sugita, Y; Yokota, M | 1 |
| Benazzi, L; Cremonesi, L; Perrella, M; Rossi-Bernardi, L | 1 |
| Kitagawa, T; Nagai, K; Tsubaki, M | 1 |
| Friedman, JM; Lyons, KB | 1 |
| Alben, JO; Bare, GH | 1 |
| Huestis, WH; Nelson, MJ | 1 |
| Krümpelmann, D; Ribbing, W; Rüterjans, H | 1 |
| Ribbing, W; Rüterjans, H | 2 |
| Gibson, QH; Morris, RJ | 1 |
| Lindahl, J; Werner, B | 1 |
| Beece, D; Eisenstein, L; Frauenfelder, H; Good, D; Marden, MC; Reinisch, L; Reynolds, AH; Sorensen, LB; Yue, KT | 1 |
| Morgan, WT; Muller-Eberhard, U; Shaklai, N; Sharma, VS | 1 |
| Clark, P; Ikeda-Saito, M; Matsuoka, A; Olson, JS; Stuehr, DJ | 1 |
| Fukuto, JM; Griscavage, JM; Ignarro, LJ; Komori, Y | 1 |
| Gibson, QH; Regan, RM; Shibayama, N; Yonetani, T | 1 |
| Meunier, B; Rich, PR; Rodriguez-Lopez, JN; Smith, AT; Thorneley, RN | 1 |
| Davydov, D; Gill, E; Heremans, K; Hui Bon Hoa, G; Jung, C | 1 |
| Admiraal, SJ; Dou, Y; George, GN; Ikeda-Saito, M; Krzywda, S; Li, T; Olson, JS; Pickering, IJ; Prince, RC; Wilkinson, AJ | 1 |
| Jünemann, S; Wrigglesworth, JM | 1 |
| Service, RF | 1 |
| Marletta, MA; Pufahl, RA | 1 |
| Ikeda-Saito, M; Rousseau, DL; Stuehr, DJ; Wang, J | 1 |
| Jewsbury, P; Kitagawa, T | 1 |
| Kharitonov, VG; Koesling, D; Magde, D; Pilz, RB; Sharma, VS | 1 |
| Burstyn, JN; Dawson, JH; Dierks, EA; Hawkins, BK; Yu, AE | 1 |
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| Fujii, H; Ikeda-Saito, M; Matera, KM; Migita, CT; Sato, M; Sun, D; Yoshida, T; Zhang, X | 1 |
| Anfinrud, PA; Jackson, TA; Lim, M; Olson, JS; Phillips, GN; Schotte, F; Smirnov, AV; Soman, J; Wulff, M | 1 |
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| Chuong, TT; Hamakawa, S; Itoh, T; Matsuura, SI; Shimizu, T; Tanaike, O | 1 |
| Oh, JY; Patel, RP; Williams, A | 1 |
| Amanullah, S; Dey, A; Saha, P; Saha, R | 1 |
| Chao, A; Goulding, CW | 1 |
| Anselmi, M; Cerutti, G; Exertier, C; Freda, I; Milazzo, L; Montemiglio, LC; Parisi, G; Savino, C; Scaglione, A; Smulevich, G; Vallone, B | 1 |
| Horst, BG; Marletta, MA; Nazarian, AA; Stewart, EM | 1 |
| Barreto, GA; Bernhardt, PV; Carepo, MSP; Diógenes, ICN; Gondim, ACS; Guimarães, WG; Lopes, LGF; Paulo, TF; Sousa, EHS | 1 |
| Kishimoto, Y; Kondo, K; Momiyama, Y | 1 |
| Liebl, U; Ramodiharilafy, R; Salman, M; Villamil Franco, C; Vos, MH | 1 |
| Bottino-Rojas, V; Dunkov, BC; Oliveira, PL; Paiva-Silva, GO; Pereira, LOR; Silva, G; Talyuli, OAC | 1 |
| Manoj, KM; Soman, V | 1 |
| Adach, W; Błaszczyk, M; Olas, B | 1 |
| Ichiyanagi, K; Ohki, M; Park, SY; Sato-Tomita, A; Shibayama, N | 1 |
| Bednarczyk, P; Koprowski, P; Kulawiak, B; Kunz, WS; Rotko, D; Szewczyk, A | 1 |
| Mizuno, M; Mizutani, Y; Tahara, S | 1 |
| Coffey, MP; Kring, EA; Maisels, MJ | 1 |
| Bories, GFP; Fox, TE; Isakson, BE; Leitinger, N; Serbulea, V; Yeudall, S | 1 |
| Gessner, G; Heinemann, SH; Hoshi, T; Rühl, P; Westerhausen, M | 1 |
| Kapka-Skrzypczak, L; Kurzepa, J; Osiak, W; Wątroba, S | 1 |
| Benninghoff, AD; Berreau, LM; Lazarus, LS | 1 |
| Fujii, H; Ikeda-Saito, M; Ishikawa, H; Matsui, T; Mizutani, Y; Nambu, S; Takahashi, S; Tsumoto, K | 1 |
| Blomberg, A; Ghorbani, R; Schmidt, FM | 1 |
| Hasegawa, K; Kobayashi, Y; Momotake, A; Neya, S; Ogura, T; Ohta, T; Saito, M; Seto, M; Shibata, T; Suzuki, A; Yamamoto, Y; Yanagisawa, S | 1 |
| Artamonov, M; Balducci, L; Cammarata, M; Chen, LX; Hayes, D; Hoffman, BM; Lemke, HT; Lestrange, PJ; Li, X; Mara, MW; Seideman, T; Shelby, ML; Wildman, A; Zhu, D | 1 |
| Vítek, L | 1 |
| Baird, JH; Kato, GJ; Mendelsohn, L; Minniti, CP; van Beers, EJ; van Vuren, AJ | 1 |
| Brenneisen, P; Brilhaus, D; Stahl, W; Stucki, D; Weber, APM; Westhoff, P | 1 |
| Giardina, B | 1 |
| Mak, PJ; Snyder, SN | 1 |
| Bowman, HE; Burstyn, JN; Dent, MR; McCaslin, DR; Roberts, MG; Weaver, BR | 1 |
| Calvano, CD; Cataldi, TRI; Console, L; Giangregorio, N; Incampo, G; Indiveri, C; Marino, T; Prejanò, M; Russo, N; Scalise, M; Tonazzi, A | 1 |
| Bajrami, S; Chen, X; Chen, YT; Chen, Z; Du, YN; Hissong, EM; Li, Y; Lin, A; Tan, AY; Torres, LK; Xiang, JZ; Zhang, C; Zhang, G; Zhang, T | 1 |
| Li, H; Ma, A; Wu, S | 1 |
| Silva, RCMC; Travassos, LH; Vasconcelos, LR | 1 |
| Badmus, OO; Hinds, TD; Stec, DE; Tiribelli, C | 1 |
| Carvalho, E; Leal, EC | 1 |
| Hirao, H; Liu, S; Sun, H; Xia, S; Yue, D | 1 |
| Burstyn, JN; Dent, MR; Roberts, MG; Weaver, BR | 1 |
| Alonso de Armiño, DJ; Becucci, M; Campagni, L; Dali, A; Estrin, DA; Hofbauer, S; Patil, G; Sebastiani, F; Smulevich, G | 1 |
| Feng, L; Liao, W; Liu, Y; Ren, J; Wei, L | 1 |
129 review(s) available for carbon monoxide and heme
| Article | Year |
|---|---|
Allosteric interpretation of haemoglobin properties.
Topics: Allosteric Site; Binding Sites; Carbon Monoxide; Chemical Phenomena; Chemistry, Organic; Chemistry, Physical; Cysteine; Diphosphoglyceric Acids; Heme; Hemoglobins; Hemoglobins, Abnormal; Hydrogen-Ion Concentration; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Organic Chemistry Phenomena; Organophosphorus Compounds; Oxygen; Protein Conformation; Protons; Spin Labels; Structure-Activity Relationship | 1975 |
[Physical enzymology (author's transl)].
Topics: Carbon Monoxide; Catalase; Chemical Phenomena; Chemistry; Circular Dichroism; Cytochrome c Group; Cytochrome P-450 Enzyme System; Electron Spin Resonance Spectroscopy; Enzyme Induction; Heme; Hemeproteins; Hemoglobins; Magnetic Resonance Spectroscopy; Magnetics; Models, Molecular; Myoglobin; Oxygen; Peroxidases; Spectrum Analysis | 1975 |
Oxygen sensing heme proteins: monoxygenases, myoglobin and hemoglobin.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Electron Transport; Heme; Hemoglobins; Kinetics; Ligands; Myoglobin; Oxygen Consumption; Oxygenases; Photolysis; Structure-Activity Relationship; Temperature; Thermodynamics | 1977 |
Pseudomonad and hepatic L-tryptophan 2, 3-dioxygenase.
Topics: Animals; Carbon Monoxide; Copper; Heme; Liver; Macromolecular Substances; Molecular Weight; Pseudomonas; Rats; Species Specificity; Tryptophan Oxygenase | 1976 |
Ligand binding properties of cytochromes c'.
Topics: Amino Acid Sequence; Binding Sites; Carbon Monoxide; Chromatium; Cyanides; Cytochrome c Group; Heme; Ligands; Molecular Sequence Data; Rhodospirillum | 1991 |
Mechanisms regulating the reactions of human hemoglobin with oxygen and carbon monoxide.
Topics: Animals; Biomechanical Phenomena; Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Hemoglobins; Hemoglobins, Abnormal; Humans; Ligands; Mutagens; Oxygen; Oxygen Consumption; Receptors, Drug | 1990 |
Flash photolysis studies of respiratory hemoproteins: analyses of the factors modulating the reactivity of heme-iron, active center of the proteins.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome-c Peroxidase; Heme; Hemeproteins; Humans; Myoglobin; Photolysis | 1987 |
[Electronic structure of the binding of O2, CO and NO with heme iron].
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Ligands; Nitric Oxide; Oxygen; Protoporphyrins | 1987 |
Sources, characteristics, and fate of atmospheric carbon monoxide.
Topics: Adsorption; Air; Air Pollution; Aircraft; Carbon Monoxide; Chemical Phenomena; Chemistry; Circadian Rhythm; Fires; Fossil Fuels; Heme; Oxidation-Reduction; Plant Development; Porphyrins; Seasons; Smog; Smoke; Smoking; Soil Microbiology; Technology; Ultraviolet Rays; Vehicle Emissions; Weather | 1970 |
[Membrane-bound hemoproteins in anaerobically grown yeast cells].
Topics: Carbon Monoxide; Culture Media; Cytochromes; Electron Transport Complex IV; Heme; Iron; Mitochondria; Oxygen; Proteins; Yeasts | 1968 |
[Molecular aspects of allosterism in hemoglobin].
Topics: Binding Sites; Carbon Monoxide; Chemical Phenomena; Chemistry; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Magnetic Resonance Spectroscopy; Molecular Biology; Optical Rotatory Dispersion; Spectrum Analysis | 1970 |
Hemoglobin.
Topics: Animals; Antibodies; Carbon Monoxide; Chemical Phenomena; Chemistry; Crystallization; Cyanates; Electron Spin Resonance Spectroscopy; Haptoglobins; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Infrared Rays; Iron; Kinetics; Magnetic Resonance Spectroscopy; Models, Structural; Mutation; Osmolar Concentration; Oxidation-Reduction; Oxygen; Species Specificity; Spectrophotometry; Sulfhydryl Compounds; Thermodynamics | 1970 |
Formation of bilirubin from erythroid and nonerythroid sources.
Topics: Anemia, Aplastic; Animals; Bile Pigments; Bilirubin; Blood Transfusion; Carbon Isotopes; Carbon Monoxide; Erythrocyte Aging; Erythrocytes; Erythropoiesis; Feces; Glycine; Heme; Hemoglobins; Humans; Hyperbilirubinemia; Levulinic Acids; Nitrogen Isotopes; Rats; Tritium | 1972 |
Renal degradation of hemoglobin.
Topics: Amino Acids; Anemia, Hemolytic; Anemia, Sickle Cell; Animals; Bilirubin; Carbon Isotopes; Carbon Monoxide; Glomerular Filtration Rate; Haptoglobins; Heart Valve Prosthesis; Heme; Hemoglobins; Hemoglobinuria, Paroxysmal; Humans; Iron; Iron Isotopes; Kidney; Malaria; Microsomes; Oxygenases; Protein Binding; Rats; Thalassemia | 1972 |
Endogenous carbon monoxide metabolism.
Topics: Bilirubin; Blood Gas Analysis; Carbon Monoxide; Carboxyhemoglobin; Heme; Humans; Infrared Rays; Spectrum Analysis | 1973 |
Hemolysis in sickle cell disease.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Carbon Monoxide; Carbon Radioisotopes; Child; Chromium Radioisotopes; Drug Interactions; Erythrocyte Aging; Erythrocytes, Abnormal; Female; Fetal Hemoglobin; Glucosephosphate Dehydrogenase Deficiency; Half-Life; Heme; Hemoglobin, Sickle; Hemoglobins; Hemolysis; Humans; Male; Middle Aged; Mononuclear Phagocyte System; Nitrogen Isotopes; Oxygen; Splenectomy; Technetium; Terminology as Topic | 1974 |
Toxicological appraisal of carbon monoxide.
Topics: Adaptation, Physiological; Air Pollution; Altitude; Animals; Carbon Monoxide; Cardiovascular System; Central Nervous System; Environmental Exposure; Heme; Hemoglobins; Humans | 1969 |
Endogenous carbon monoxide production.
Topics: Anemia; Animals; Bilirubin; Carbon Isotopes; Carbon Monoxide; Dogs; Erythrocytes; Glycine; Heme; Hemoglobins; Humans; Liver; Muscles; Rats; Spleen | 1970 |
The carbon monoxide body stores.
Topics: Anemia, Hemolytic; Animals; Binding Sites; Carbon Isotopes; Carbon Monoxide; Cytochromes; Dogs; Heme; Hemoglobins; Humans; Hypoxia; Liver; Muscles; Myocardium; Myoglobin; Oxygen; Partial Pressure; Protein Binding; Pulmonary Alveoli; Pulmonary Circulation; Respiration; Smoking | 1970 |
Quantitation of red cell and heme production and destruction using radioisotope kinetics.
Topics: Animals; Autoradiography; Blood Volume Determination; Carbon Isotopes; Carbon Monoxide; Cell Survival; Chromium Isotopes; Erythrocyte Count; Erythrocytes; Esterases; Feces; Guinea Pigs; Haplorhini; Hematologic Diseases; Heme; Humans; Iron; Iron Isotopes; Kinetics; Mathematics; Metabolic Clearance Rate; Phosphorus Isotopes; Pyrroles; Radioisotopes; Tritium | 1968 |
Considerations for the design of useful synthetic oxygen carriers.
Topics: Animals; Carbon Monoxide; Heme; Hemeproteins; Hemoglobins; Metalloporphyrins; Oxygen; Polystyrenes | 1982 |
Sources of carbon monoxide (CO) in biological systems and applications of CO detection technologies.
Topics: Animals; Bilirubin; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Plants | 1994 |
[Biological role of carbon monoxide in nervous system function].
Topics: Carbon Monoxide; Heme; Humans; Learning; Memory; Nervous System Physiological Phenomena; Oxidation-Reduction; Pain; Platelet Aggregation; Vasodilation | 1996 |
Carbon monoxide excretion, not oxygen secretion?
Topics: Acclimatization; Altitude; Carbon Dioxide; Carbon Monoxide; Carboxyhemoglobin; Diffusion; Heme; Hemeproteins; Humans; Hypoxia; Oxygen; Oxyhemoglobins; Partial Pressure; Pulmonary Alveoli; Pulmonary Gas Exchange | 1996 |
New physiological importance of two classic residual products: carbon monoxide and bilirubin.
Topics: Animals; Antioxidants; Bilirubin; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Homeostasis; Humans; Second Messenger Systems | 1997 |
Pathogenicity of carbon monoxide.
Topics: Brain; Carbon Monoxide; Carbon Monoxide Poisoning; Cytochromes; Heme; Hemoglobins; Humans; Myocardium; Myoglobin; Oxidation-Reduction; Oxygen | 1997 |
Carbon monoxide and vascular cell function (review).
Topics: Animals; Autocrine Communication; Blood Vessels; Carbon Monoxide; Heme; Humans; Muscle Tonus; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Paracrine Communication; Vascular Diseases | 1998 |
Heme-based sensors in biological systems.
Topics: Animals; Bacterial Proteins; Biological Transport; Biosensing Techniques; Carbon Monoxide; Enzyme Activation; Escherichia coli Proteins; Fimbriae Proteins; Guanylate Cyclase; Heme; Hemeproteins; Histidine Kinase; Nitric Oxide; Oxygen; Protein Conformation | 1999 |
Carbon monoxide: from toxin to endogenous modulator of cardiovascular functions.
Topics: Blood Pressure; Carbon Monoxide; Cardiovascular Physiological Phenomena; Heme; Heme Oxygenase (Decyclizing); Humans; Muscle, Smooth, Vascular; Solitary Nucleus; Vasoconstriction; Vasodilation | 1999 |
Cell biology of heme.
Topics: 5-Aminolevulinate Synthetase; Animals; Carbon Monoxide; Erythrocytes; Heme; Heme Oxygenase (Decyclizing); Humans; Iron-Regulatory Proteins; Iron-Sulfur Proteins; Nitric Oxide; Receptors, Transferrin; RNA-Binding Proteins | 1999 |
Zinc protoporphyrin: A metabolite with a mission.
Topics: Anemia, Iron-Deficiency; Animals; Animals, Newborn; Bilirubin; Carbon Monoxide; Erythrocytes; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Humans; Hyperbilirubinemia; Lead Poisoning; Metalloporphyrins; Protoporphyrins | 1999 |
Heme oxygenase, carbon monoxide, and interstitial cells of Cajal.
Topics: Animals; Carbon Monoxide; Digestive System; Digestive System Physiological Phenomena; Gastrointestinal Motility; Heme; Heme Oxygenase (Decyclizing); Humans; Intestinal Mucosa; Intestines; Middle Aged; Muscle, Smooth; Potassium Channels | 1999 |
[The heme oxygenase system and its physiopathology].
Topics: Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Hyperbilirubinemia; Iron; Porphyrias | 1999 |
Carbon monoxide detection and biological investigations.
Topics: Animals; Bilirubin; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Mice; Mice, Transgenic | 2000 |
CO sensing and regulation of gene expression by the transcriptional activator CooA.
Topics: Bacterial Proteins; Carbon Monoxide; DNA-Directed RNA Polymerases; Gene Expression Regulation, Bacterial; Heme; Hemeproteins; Ligands; Models, Molecular; Oxidation-Reduction; Protein Structure, Quaternary; Recombinant Fusion Proteins; Rhodospirillum rubrum; Trans-Activators | 2000 |
Recent advances in heme-protein sensors.
Topics: Allosteric Regulation; Bacterial Proteins; Biosensing Techniques; Carbon Monoxide; Heme; Hemeproteins; Models, Molecular; Myoglobin; Nitric Oxide; Oxygen; Protein Conformation | 2001 |
Carbon monoxide and bilirubin production in neonates.
Topics: Animals; Bilirubin; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Infant, Newborn; Iron; Isoenzymes | 2001 |
Heme-based sensors: theoretical modeling of heme-ligand-protein interactions.
Topics: Biosensing Techniques; Carbon Monoxide; Heme; Hemeproteins; Models, Molecular; Myoglobin; Nitric Oxide; Oxygen; Quantum Theory | 2001 |
A novel strategy against ischemia and reperfusion injury: cytoprotection with heme oxygenase system.
Topics: Animals; Biliverdine; Carbon Monoxide; Cytoprotection; Enzyme Induction; Free Radicals; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Iron; Ischemia; Membrane Proteins; Oxygen; Reperfusion Injury | 2002 |
Heme degradation and human disease: diversity is the soul of life.
Topics: Animals; Antioxidants; Bilirubin; Carbon Monoxide; Cardiovascular Diseases; Crigler-Najjar Syndrome; Gene Expression Regulation, Enzymologic; Gilbert Disease; Glucuronosyltransferase; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; Humans; Infant, Newborn; Isoenzymes; Jaundice, Neonatal; Malaria; Membrane Proteins; Nervous System Diseases; Oxygen | 2002 |
Metabolic modulation of carbon monoxide toxicity.
Topics: Air Pollutants; Animals; Antioxidants; Carbon Monoxide; Carbon Monoxide Poisoning; Dose-Response Relationship, Drug; Heme; Humans; Inactivation, Metabolic; Inhalation Exposure; Oxidative Stress | 2002 |
[Heme oxygenase and carbon monoxide: the protection or the injury of cells?].
Topics: Animals; Biliverdine; Carbon Monoxide; Catalysis; Heme; Heme Oxygenase (Decyclizing); Oxidative Stress | 2002 |
Mechanisms of ligand discrimination by heme proteins.
Topics: Animals; Carbon Monoxide; Carrier Proteins; Heme; Hemeproteins; Humans; Ligands; Models, Molecular; Nitric Oxide; Oxygen; Protein Conformation | 2003 |
Carbon monoxide and bile pigments: surprising mediators of vascular function.
Topics: Bile Pigments; Carbon Monoxide; Endothelium, Vascular; Heme; Heme Oxygenase (Decyclizing); Humans; Muscle, Smooth, Vascular; Up-Regulation | 2002 |
Induced adaptive resistance to oxidative stress in the CNS: a discussion on possible mechanisms and their therapeutic potential.
Topics: Adaptation, Physiological; Carbon Monoxide; Central Nervous System; Drug Resistance; Free Radicals; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Iron; Membrane Proteins; Myelitis; Neurodegenerative Diseases; Nitric Oxide; Oxidative Stress; Spinal Cord Injuries | 2003 |
Myoglobin: the hydrogen atom of biology and a paradigm of complexity.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry, Physical; Crystallography, X-Ray; Heme; Hydrogen; Lasers; Models, Molecular; Molecular Structure; Myoglobin; Oxygen; Photolysis; Protein Conformation | 2003 |
Heme oxygenase-1: unleashing the protective properties of heme.
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Membrane Proteins; Protective Agents; Signal Transduction | 2003 |
What role does the heme-- heme oxygenase--carbon monoxide system play in vasoregulation?
Topics: Animals; Blood Vessels; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Vasoconstriction | 2003 |
SOME ASPECTS OF THE STRUCTURE OF HEMOGLOBIN.
Topics: Amino Acids; Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Hemoglobins; Hemoglobins, Abnormal; Horses; Oxygen; Peptides; Research; X-Ray Diffraction | 1964 |
Biochemical and biophysical properties of the CO-sensing transcriptional activator CooA.
Topics: Bacterial Proteins; Carbon Monoxide; Heme; Hemeproteins; Models, Molecular; Oxidation-Reduction; Rhodospirillum rubrum; Trans-Activators | 2003 |
Synthetic models for heme-copper oxidases.
Topics: Animals; Carbon Monoxide; Copper; Cytochromes; Heme; Iron; Ligands; Models, Molecular; Molecular Structure; Oxidation-Reduction; Oxidoreductases; Oxygen | 2004 |
Carbon monoxide in biology and medicine.
Topics: Animals; Apoptosis; Carbon Monoxide; Heme; Humans; Molecular Structure; Nitric Oxide; Oxygen; Signal Transduction; Synaptic Transmission | 2004 |
[Heme oxygenase and atherosclerosis].
Topics: Animals; Apoptosis; Arteriosclerosis; Carbon Monoxide; Cell Division; Heme; Heme Oxygenase (Decyclizing); Humans; Muscle, Smooth, Vascular; Protoporphyrins | 2003 |
UV optical absorption by protein radicals in cytochrome c oxidase.
Topics: Animals; Carbon Monoxide; Cattle; Copper; Electron Transport Complex IV; Free Radicals; Heme; Hydrogen-Ion Concentration; In Vitro Techniques; Myocardium; Oxygen; Spectrophotometry, Ultraviolet; Tryptophan; Tyrosine | 2004 |
Active site structure of the aa3 quinol oxidase of Acidianus ambivalens.
Topics: Acidianus; Carbon Monoxide; Catalytic Domain; Cyanides; Electron Transport Complex IV; Heme; Hydrogen-Ion Concentration; Ligands; Oxidation-Reduction; Photolysis; Proton Pumps; Spectrum Analysis, Raman | 2004 |
The bacterial cytochrome cbb3 oxidases.
Topics: Bacteria; Carbon Monoxide; Electrochemistry; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Gene Expression; Genes, Bacterial; Heme; Kinetics; Ligands; Proton Pumps; Pseudomonas stutzeri | 2004 |
Protective role of heme oxygenase in the blood vessel wall during atherogenesis.
Topics: Animals; Antioxidants; Arteriosclerosis; Bilirubin; Biliverdine; Blood Vessels; Carbon Monoxide; Endothelium, Vascular; Ferritins; Gene Expression Regulation, Enzymologic; Genetic Therapy; Heme; Heme Oxygenase (Decyclizing); Humans; Isoenzymes; Lipoproteins, LDL; Oxidative Stress | 2004 |
Heme oxygenase and its products in the nervous system.
Topics: Animals; Bilirubin; Carbon Monoxide; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase (Decyclizing); Iron; Isoenzymes; Molecular Structure; Nervous System | 2004 |
Heme catabolism and heme oxygenase in neurodegenerative disease.
Topics: Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Iron; Isoenzymes; Molecular Structure; Neurodegenerative Diseases; Protein Conformation; tau Proteins | 2004 |
CO sniffing through heme-based sensor proteins.
Topics: Animals; Bacterial Proteins; Base Sequence; Brain; Carbon Monoxide; Heme; Hemeproteins; Humans; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Signal Transduction; Transcription Factors | 2004 |
Heme oxygenase system in ischemia and reperfusion injury.
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Enzyme Induction; Ferritins; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Iron; Membrane Proteins; Reperfusion Injury | 2004 |
Heme oxygenase-1 as a protective gene.
Topics: Angioplasty, Balloon; Animals; Bilirubin; Carbon Monoxide; Diabetes Mellitus, Type 1; Graft Rejection; Graft Survival; Heart Transplantation; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Islets of Langerhans Transplantation; Membrane Proteins; Mice; Oxidoreductases Acting on CH-CH Group Donors; Protein Isoforms; Rats; Shock, Septic; Transplantation, Heterologous | 2002 |
Structural bases for heme binding and diatomic ligand recognition in truncated hemoglobins.
Topics: Amino Acid Sequence; Animals; Carbon Monoxide; Cyanides; Heme; Hemoglobins; Ligands; Models, Molecular; Molecular Sequence Data; Nitric Oxide; Oxygen; Protein Conformation; Sequence Alignment; Truncated Hemoglobins | 2005 |
CooA, a paradigm for gas sensing regulatory proteins.
Topics: Bacterial Proteins; Carbon Monoxide; Gene Expression Regulation, Bacterial; Heme; Hemeproteins; Models, Molecular; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Trans-Activators | 2005 |
Ligand-protein interactions in nitric oxide synthase.
Topics: Carbon Monoxide; Catalytic Domain; Cysteine; Heme; Hydrogen Bonding; Isoenzymes; Ligands; Molecular Structure; Nitric Oxide Synthase; Oxygen; Spectrum Analysis, Raman | 2005 |
A hierarchy of functionally important relaxations within myoglobin based on solvent effects, mutations and kinetic model.
Topics: Binding Sites; Carbon Monoxide; Heme; Kinetics; Ligands; Models, Molecular; Models, Theoretical; Mutation; Myoglobin; Protein Binding; Protein Conformation; Solvents; Trehalose | 2005 |
Heme regulation in traumatic brain injury: relevance to the adult and developing brain.
Topics: Animals; Bilirubin; Brain; Carbon Monoxide; Heme; Humans; Iron; Mice; Oxidative Stress; Prognosis; Rats; Subarachnoid Hemorrhage, Traumatic | 2005 |
[Structure and mechanism of heme oxygenase].
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Catalysis; Electrons; Heme; Heme Oxygenase (Decyclizing); Humans; Iron; Ligands; NADPH-Ferrihemoprotein Reductase; Oxidoreductases Acting on CH-CH Group Donors; Protein Conformation | 2005 |
Carbon monoxide: endogenous production, physiological functions, and pharmacological applications.
Topics: Animals; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Ion Channels; Nitric Oxide Synthase | 2005 |
Products of heme oxygenase and their potential therapeutic applications.
Topics: Adult; Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase-1; Humans; Iron | 2006 |
Heme oxygenase-1 and cardiovascular disease.
Topics: Animals; Atherosclerosis; Bilirubin; Cadmium Chloride; Carbon Monoxide; Cardiovascular Diseases; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Heme; Heme Oxygenase-1; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Oxidative Stress; Protein Isoforms | 2006 |
Heme oxygenase-1 and transplantation tolerance.
Topics: Animals; Biliverdine; Carbon Monoxide; Graft Rejection; Heart Transplantation; Heme; Heme Oxygenase-1; Mice; Transplantation Tolerance | 2006 |
Quo vadis porphyrin chemistry?
Topics: Carbon Monoxide; Heme; Models, Biological; Photochemotherapy; Porphyrins | 2006 |
Intrarenal renin-angiotensin system and counteracting protective mechanisms in angiotensin II-dependent hypertension.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Blood Pressure; Carbon Monoxide; Cyclooxygenase Inhibitors; Eicosanoids; Heme; Heme Oxygenase (Decyclizing); Hypertension; Hypertension, Renal; Renin-Angiotensin System | 2007 |
Properties of an unusual heme cofactor in PLP-dependent cystathionine beta-synthase.
Topics: Carbon Monoxide; Catalysis; Cystathionine beta-Synthase; Heme; Hemeproteins; Humans; Iron; Models, Molecular; Nitric Oxide; Pyridoxal Phosphate | 2007 |
[Heme oxygenase as a potential therapeutic target for hepatoprotection].
Topics: Acetaminophen; Animals; Biliverdine; Carbon Monoxide; Catalysis; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytoprotection; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Garlic; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Isoenzymes; Liver; Liver Diseases; Oxidative Stress; Protective Agents | 2007 |
Heme-hemopexin: a 'chronosteric' heme-protein.
Topics: Animals; Binding Sites; Carbon Monoxide; Heme; Hemopexin; Models, Molecular; Nitric Oxide; Oxidation-Reduction; Oxygen; Protein Binding; Protein Structure, Tertiary | 2007 |
Cerebroprotective functions of HO-2.
Topics: Animals; Bilirubin; Brain; Brain Injuries; Carbon Monoxide; Cerebrovascular Circulation; Cerebrovascular Disorders; Endothelium, Vascular; Heme; Heme Oxygenase (Decyclizing); Humans; Isoenzymes; Neurons; Oxidative Stress; Receptors, Glutamate; Seizures | 2008 |
Heme oxygenase-1 and the vascular bed: from molecular mechanisms to therapeutic opportunities.
Topics: Animals; Apoptosis; Biliverdine; Carbon Monoxide; Cardiovascular Agents; Cardiovascular Diseases; Child; Diabetes Complications; Endothelium, Vascular; Enzyme Induction; Female; Genetic Therapy; Heme; Heme Oxygenase-1; Humans; Inflammation; Iron; Male; Mice; Mice, Knockout; Neovascularization, Physiologic; Rabbits; Rats; Vasomotor System | 2008 |
A central role for free heme in the pathogenesis of severe malaria: the missing link?
Topics: Animals; Carbon Monoxide; Disease Models, Animal; Heme; Heme Oxygenase-1; Hemoglobins; Humans; Malaria; Malaria, Cerebral; Models, Biological | 2008 |
Modulation of BKCa channel gating by endogenous signaling molecules.
Topics: Animals; Biological Factors; Carbon Monoxide; Fatty Acids; Heme; Humans; Large-Conductance Calcium-Activated Potassium Channels; Protons; Signal Transduction | 2009 |
Heme oxygenase-1, a critical arbitrator of cell death pathways in lung injury and disease.
Topics: Animals; Apoptosis; Biliverdine; Carbon Monoxide; Cell Proliferation; Heme; Heme Oxygenase-1; Humans; Iron; Lung; Organ Transplantation; Oxidative Stress; Reperfusion Injury; Signal Transduction; STAT Transcription Factors | 2009 |
Heme oxygenase-1/carbon monoxide: from metabolism to molecular therapy.
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Clinical Trials as Topic; Cytoprotection; Genetic Therapy; Heme; Heme Oxygenase-1; Homeostasis; Humans; Iron; Molecular Structure; Oxidative Stress; Signal Transduction | 2009 |
Interactions of multiple gas-transducing systems: hallmarks and uncertainties of CO, NO, and H2S gas biology.
Topics: Animals; Carbon Monoxide; Central Nervous System Diseases; Electron Transport; Heme; Heme Oxygenase (Decyclizing); Hemeproteins; Humans; Hydrogen Sulfide; Mitochondria; Models, Molecular; Molecular Structure; Nitric Oxide; Oxidation-Reduction; Oxygen; Signal Transduction; Tissue Distribution | 2010 |
Mechanisms of cell protection by heme oxygenase-1.
Topics: Animals; Apoptosis; Biliverdine; Carbon Monoxide; Cytoprotection; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase-1; Humans; Inflammation; Tumor Necrosis Factor-alpha | 2010 |
Haem oxygenase (HO): an overlooked enzyme of plant metabolism and defence.
Topics: Amino Acid Sequence; Carbon Monoxide; Gene Expression Regulation, Plant; Heme; Heme Oxygenase (Decyclizing); Molecular Sequence Data; Plant Proteins; Plants; Sequence Alignment | 2010 |
Signaling to heme oxygenase-1 and its anti-inflammatory therapeutic potential.
Topics: Animals; Anti-Inflammatory Agents; Bilirubin; Carbon Monoxide; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Heme; Heme Oxygenase-1; Humans; Immunomodulation; Inflammation; Isoenzymes; Myeloid Cells; Oxidation-Reduction; Signal Transduction | 2010 |
Carbon monoxide, a two-face for the protection of the liver.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Carbon Monoxide; Heme; Hepatocytes; Humans; Liver; Liver Cirrhosis; Liver Transplantation; Protective Agents | 2012 |
Therapeutic potential of carbon monoxide in multiple sclerosis.
Topics: Animals; Anti-Inflammatory Agents; Autoimmunity; Boranes; Carbon Monoxide; Carbonates; Cardiotonic Agents; Cytokines; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Guanylate Cyclase; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Inflammation; Multiple Sclerosis; Neuroimmunomodulation; Organometallic Compounds; Oxidation-Reduction; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase; Vasodilator Agents | 2012 |
The interdependence of the reactive species of oxygen, nitrogen, and carbon.
Topics: Arginine; Carbon; Carbon Monoxide; Carbon-Sulfur Lyases; Cysteine; Heme; Heme Oxygenase (Decyclizing); Humans; Hydrogen Sulfide; Nitric Oxide Synthase; Oxidation-Reduction; Oxidative Stress; Reactive Nitrogen Species; Reactive Oxygen Species | 2013 |
[Intracellular gaseous messengers, nitric oxide, carbon monoxide and hydrogen sulfide participate in apoptosis regulation].
Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Carbon Monoxide; Cells, Cultured; Gene Expression Regulation; Heme; Humans; Hydrogen Sulfide; Mice; Nitric Oxide; Second Messenger Systems; Transcription Factors | 2012 |
Redox, haem and CO in enzymatic catalysis and regulation.
Topics: Acetate-CoA Ligase; Aldehyde Oxidoreductases; Animals; Biocatalysis; Carbon Monoxide; Heme; Humans; Multienzyme Complexes; Oxidation-Reduction | 2012 |
Carbon monoxide: mechanisms of action and potential clinical implications.
Topics: Animals; Carbon Monoxide; Cardiovascular Diseases; Endothelium, Vascular; Heme; Heme Oxygenase-1; Humans; Nitric Oxide; Sepsis; Vasodilation | 2013 |
Overview of heme degradation pathway.
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Iron; Molecular Structure; Oxidation-Reduction | 2001 |
Dynamic motion and rearranged molecular shape of heme in myoglobin: structural and functional consequences.
Topics: Carbon Monoxide; Crystallography, X-Ray; Heme; Histidine; Iron; Molecular Structure; Motion; Myoglobin; Nuclear Magnetic Resonance, Biomolecular; Oxygen; Rotation | 2013 |
Carbon monoxide: present and future indications for a medical gas.
Topics: Administration, Inhalation; Animals; Anti-Inflammatory Agents; Carbon Monoxide; Dose-Response Relationship, Drug; Environmental Pollutants; Gases; Heme; Heme Oxygenase (Decyclizing); Humans; Inhalation Exposure; Risk Assessment; Signal Transduction | 2013 |
Heme sensor proteins.
Topics: Animals; Carbon Monoxide; Circadian Rhythm; Gene Expression Regulation; Guanylate Cyclase; Heme; Hemeproteins; Homeostasis; Humans; Oxidation-Reduction; Oxidative Stress; Oxygen | 2013 |
[Hemoglobin--source of reactive oxygen species].
Topics: Animals; Biliverdine; Carbon Monoxide; Cytoprotection; Erythrocytes; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Humans; Hydrogen Peroxide; Iron; Lipid Peroxidation; Oxidation-Reduction; Reactive Oxygen Species | 2013 |
Heme oxygenase-1 and gut ischemia/reperfusion injury: A short review.
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase-1; Humans; Intestines; Iron; Reperfusion Injury; Signal Transduction | 2013 |
Heme oxygenase-1: a metabolic nike.
Topics: Animals; Biosynthetic Pathways; Carbon Monoxide; Cell Respiration; Diabetes Mellitus; Heme; Heme Oxygenase-1; Hemeproteins; Humans; Iron; Mitochondria; Neoplasms | 2014 |
Photoactive metal carbonyl complexes as potential agents for targeted CO delivery.
Topics: Animals; Carbon Monoxide; Coordination Complexes; Crystallography, X-Ray; Heme; Humans; Iron Carbonyl Compounds; Metals; Models, Molecular; Signal Transduction; Vasodilation | 2014 |
Insights into redox sensing metalloproteins in Mycobacterium tuberculosis.
Topics: Carbon Monoxide; Gene Expression Regulation, Bacterial; Heme; Humans; Hypoxia; Metalloproteins; Mycobacterium tuberculosis; Nitric Oxide; Oxidation-Reduction; Oxygen; Tuberculosis | 2014 |
Hydrogen sulfide activation in hemeproteins: the sulfheme scenario.
Topics: Carbon Monoxide; Heme; Hemeproteins; Humans; Hydrogen Sulfide; Nitric Oxide | 2014 |
Novel lead structures and activation mechanisms for CO-releasing molecules (CORMs).
Topics: Animals; Carbon Monoxide; Coordination Complexes; Heme; Heme Oxygenase (Decyclizing); Humans; Metals; Nanostructures; Prodrugs; Signal Transduction | 2015 |
Effects of serum bilirubin on atherosclerotic processes.
Topics: Animals; Atherosclerosis; Bilirubin; Carbon Monoxide; Heme; Humans | 2014 |
The heme oxygenases: important regulators of pregnancy and preeclampsia.
Topics: Animals; Bilirubin; Carbon Monoxide; Female; Heme; Heme Oxygenase (Decyclizing); Humans; Placenta; Pre-Eclampsia; Pregnancy | 2014 |
The pathway of O₂to the active site in heme-copper oxidases.
Topics: Animals; Carbon Monoxide; Catalytic Domain; Cattle; Heme; Kinetics; Models, Molecular; Oxidoreductases; Oxygen; Spectroscopy, Fourier Transform Infrared; Thermus thermophilus | 2015 |
Time-resolved infrared spectroscopic studies of ligand dynamics in the active site from cytochrome c oxidase.
Topics: Carbon Monoxide; Catalytic Domain; Copper; Electron Transport Complex IV; Heme; Ligands; Models, Molecular; Spectrophotometry, Infrared | 2015 |
A review on hemeoxygenase-2: focus on cellular protection and oxygen response.
Topics: Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Heme Oxygenase (Decyclizing); Humans; Hypoxia; Large-Conductance Calcium-Activated Potassium Channels; Nitric Oxide Donors; Oxygen; Protein Isoforms | 2014 |
Carbon monoxide is not always a poison gas for human organism: Physiological and pharmacological features of CO.
Topics: Carbon Monoxide; Cardiovascular Physiological Phenomena; Gasotransmitters; Heme; Humans; Nervous System Physiological Phenomena; Signal Transduction | 2014 |
Therapeutic roles of carbon monoxide in intestinal ischemia-reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents; Carbon Monoxide; Heme; Heme Oxygenase-1; Humans; Intestinal Diseases; Reperfusion Injury | 2015 |
Gaseous O2, NO, and CO in signal transduction: structure and function relationships of heme-based gas sensors and heme-redox sensors.
Topics: Carbon Monoxide; Heme; Humans; Nitric Oxide; Oxidation-Reduction; Oxygen; Proteins; Signal Transduction | 2015 |
[Structural study of enzymes involved in heme metabolism].
Topics: Animals; Carbon Monoxide; Heme; Heme Oxygenase-1; Oxygen; Water | 2016 |
Cystathionine β-synthase and PGRMC1 as CO sensors.
Topics: Animals; Carbon Monoxide; Cystathionine beta-Synthase; Cytochrome P-450 Enzyme System; ErbB Receptors; Gene Expression Regulation; Heme; Heme Oxygenase-1; Homocystinuria; Humans; Hydrogen Sulfide; Isoenzymes; Membrane Proteins; Protein Multimerization; Receptors, Progesterone; Signal Transduction | 2016 |
Heme Oxygenases in Cardiovascular Health and Disease.
Topics: Animals; Biliverdine; Carbon Monoxide; Cardiovascular Diseases; Cardiovascular System; Heme; Heme Oxygenase (Decyclizing); Humans; Iron | 2016 |
Localized delivery of carbon monoxide.
Topics: Administration, Cutaneous; Administration, Inhalation; Administration, Oral; Animals; Biliverdine; Carbon Monoxide; Carboxyhemoglobin; Coronary Artery Disease; Diabetes Mellitus; Disease Models, Animal; Drug Delivery Systems; Heme; Heme Oxygenase-1; Humans; Organ Transplantation; Organometallic Compounds; Reperfusion Injury; Signal Transduction; Tissue Distribution | 2017 |
The Heme Oxygenase System in Hematological Malignancies.
Topics: Animals; Antineoplastic Agents; Biliverdine; Carbon Monoxide; Epigenesis, Genetic; Hematologic Neoplasms; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Iron; Models, Molecular; Oxidation-Reduction; Signal Transduction; Xenograft Model Antitumor Assays | 2017 |
Mechanistic insight into the heme-independent interplay between iron and carbon monoxide in CFTR and Slo1 BK
Topics: Carbon Monoxide; Cell Membrane; Cystic Fibrosis Transmembrane Conductance Regulator; Heme; Humans; Ion Channel Gating; Iron; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Protein Binding | 2017 |
Structural determinants of ligand binding in truncated hemoglobins: Resonance Raman spectroscopy of the native states and their carbon monoxide and hydroxide complexes.
Topics: Amino Acid Sequence; Carbon Monoxide; Heme; Hydroxides; Ligands; Spectrum Analysis, Raman; Truncated Hemoglobins | 2018 |
The Protective Role of Heme Oxygenase-1 in Atherosclerotic Diseases.
Topics: Animals; Atherosclerosis; Biliverdine; Carbon Monoxide; Coronary Artery Disease; Heme; Heme Oxygenase-1; Humans; Iron; Peripheral Arterial Disease; Reactive Oxygen Species | 2019 |
Carbon monoxide and its donors - Chemical and biological properties.
Topics: Animals; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Isoenzymes | 2020 |
Two Faces of Heme Catabolic Pathway in Newborns: A Potential Role of Bilirubin and Carbon Monoxide in Neonatal Inflammatory Diseases.
Topics: Bilirubin; Carbon Monoxide; Heme; Humans; Infant, Newborn; Infant, Newborn, Diseases; Inflammation; Reactive Oxygen Species | 2020 |
The Protective Role of the Heme Catabolic Pathway in Hepatic Disorders.
Topics: Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Liver Diseases | 2021 |
Hemoglobin: Multiple molecular interactions and multiple functions. An example of energy optimization and global molecular organization.
Topics: Carbon Monoxide; Erythrocytes; Heme; Hemoglobins; Humans; Nitric Oxide; Oxygen | 2022 |
The different facets of heme-oxygenase 1 in innate and adaptive immunity.
Topics: Adaptive Immunity; Anti-Inflammatory Agents; Antioxidants; Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Immunity, Innate; Inflammation Mediators; Iron; Reactive Oxygen Species; Transcription Factors | 2022 |
Novel Function for Bilirubin as a Metabolic Signaling Molecule: Implications for Kidney Diseases.
Topics: Bilirubin; Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Kidney Diseases; PPAR alpha; Transcription Factors | 2022 |
Heme Oxygenase-1 as Therapeutic Target for Diabetic Foot Ulcers.
Topics: Anti-Inflammatory Agents; Antioxidants; Biliverdine; Carbon Monoxide; Diabetes Mellitus; Diabetic Foot; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Iron | 2022 |
Carbon Monoxide-Sensing Transcription Factors: Regulators of Microbial Carbon Monoxide Oxidation Pathway Gene Expression.
Topics: Bacterial Proteins; Carbon Monoxide; Gene Expression; Heme; Oxidation-Reduction; Transcription Factors | 2023 |
Carbon monoxide/heme oxygenase system in plant: Roles in abiotic stress response and crosstalk with other signals molecules.
Topics: Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Hydrogen Peroxide; Hydrogen Sulfide; Plants; Stress, Physiological | 2023 |
3 trial(s) available for carbon monoxide and heme
| Article | Year |
|---|---|
Heme catabolism during short-term treatment with phenobarbital, diazepam and oxazepam.
Topics: Adult; Bilirubin; Carbon Monoxide; Depression, Chemical; Diazepam; Heme; Hemoglobins; Humans; Male; Oxazepam; Phenobarbital; Stimulation, Chemical; Time Factors | 1975 |
The contributions of erythropoietic and nonerythropoietic haem turnover to the early labelle peak of endogenous CO formation in man.
Topics: Adult; Blood Transfusion, Autologous; Carbon Monoxide; Erythrocyte Count; Erythropoiesis; Glycine; Heme; Hemoglobins; Humans; Male; Middle Aged; Reticulocytes | 1980 |
Lactate dehydrogenase to carboxyhemoglobin ratio as a biomarker of heme release to heme processing is associated with higher tricuspid regurgitant jet velocity and early death in sickle cell disease.
Topics: Adult; Anemia, Sickle Cell; Biomarkers; Carbon Monoxide; Carboxyhemoglobin; Heme; Hemolysis; Humans; L-Lactate Dehydrogenase; Tricuspid Valve Insufficiency | 2021 |
1078 other study(ies) available for carbon monoxide and heme
| Article | Year |
|---|---|
Heme-linked protonation of HCN, CO, NO and O2 complexes of reduced horseradish peroxidases.
Topics: Binding Sites; Carbon Monoxide; Cyanides; Heme; Horseradish Peroxidase; Hydrogen-Ion Concentration; Kinetics; Nitric Oxide; Oxygen; Oxygen Consumption; Peroxidases; Protein Binding; Spectrophotometry | 1975 |
Cooperative reactions of poly-L-lysine-heme complex with molecular oxygen, carbon monoxide, or cyanide ion.
Topics: Binding Sites; Calorimetry; Carbon Monoxide; Circular Dichroism; Cyanides; Heme; Hydrogen-Ion Concentration; Kinetics; Lysine; Oxygen; Partial Pressure; Peptides; Protein Binding; Protein Conformation; Spectrophotometry; Thermodynamics | 1976 |
Heme-linked proton dissociation of carbon monoxide complexes of myoglobin and peroxidase.
Topics: Animals; Binding Sites; Carbon Monoxide; Heme; Horseradish Peroxidase; Hydrogen-Ion Concentration; Muscles; Myoglobin; Oxidation-Reduction; Peroxidases; Protein Binding; Spectrophotometry; Whales | 1976 |
Magnetic resonance studies of the binding of 13C-labeled carbon monoxide to myoglobins and hemoglobins containing modified hemes.
Topics: Apoproteins; Binding Sites; Carbon Monoxide; Heme; Hemoglobins; Hydrogen-Ion Concentration; Ligands; Magnetic Resonance Spectroscopy; Myoglobin; Protein Conformation; Structure-Activity Relationship | 1977 |
Electronic and steric factors affecting ligand binding: horse hemoglobins containing 2,4-dimethyldeuteroheme and 2,4-dibromodeuteroheme.
Topics: Animals; Carbon Monoxide; Heme; Hemoglobins; Horses; Hydrogen-Ion Concentration; Ligands; Oxygen; Protein Binding; Spectrophotometry | 1977 |
The interaction between the heme c and heme d moieties of Pseudomonas nitrite reductase as revealed by magnetic and natural circular dichroism studies.
Topics: Apoenzymes; Binding Sites; Carbon Monoxide; Circular Dichroism; Cyanides; Heme; Hydrogen-Ion Concentration; Imidazoles; Magnetics; NADH, NADPH Oxidoreductases; Nitrite Reductases; Oxidation-Reduction; Protein Binding; Protein Conformation; Pseudomonas | 1977 |
Hemoglobin Raleigh (beta1 valine replaced by acetylalanine). Structural and functional characterization.
Topics: Adult; Alanine; Amino Acids; Carbon Monoxide; Female; Heme; Hemoglobin A; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Oxygen; Pedigree; Peptide Fragments; Phytic Acid; Valine | 1977 |
A new method for determination of microsomal haem oxygenase (EC 1.14.99.3) based on quantitation of carbon monoxide formation.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Heme; In Vitro Techniques; Methemalbumin; Methods; Microsomes; Mixed Function Oxygenases; NADP; Rats | 1978 |
Destruction of heme and hemoproteins mediated by liver microsomal reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Heme; Hemeproteins; Male; Microsomes, Liver; NADP; Oxidation-Reduction; Rats; Spectrophotometry | 1978 |
The relation between carbon monoxide binding and the conformational change of hemoglobin.
Topics: Carbon Monoxide; Carboxyhemoglobin; Heme; Hemoglobins; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Protein Binding; Protein Conformation | 1978 |
Degradation of cytochrome P-450 haem by carbon tetrachloride and 2-allyl-2-isopropylacetamide in rat liver in vivo and in vitro. Involvement of non-carbon monoxide-forming mechanisms.
Topics: Acetamides; Allylisopropylacetamide; Aminolevulinic Acid; Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Heme; Heme Oxygenase (Decyclizing); In Vitro Techniques; Kidney; Lipid Metabolism; Liver; Male; Microsomes, Liver; Rats | 1979 |
Quantitative infrared spectroscopy of CO complexes of cytochrome c oxidase, hemoglobin and myoglobin: evidence for one CO per heme.
Topics: Animals; Carbon Monoxide; Cattle; Electron Transport Complex IV; Heme; Hemoglobins; Humans; Myocardium; Myoglobin; Protein Binding; Protein Conformation; Spectrophotometry, Infrared | 1975 |
Magnetic circular dichroism studies of myoglobin complexes. Correlations with heme spin state and axial ligation.
Topics: Carbon Monoxide; Circular Dichroism; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Heme; Myoglobin; Oxidation-Reduction; Spectrum Analysis | 1976 |
Spectroelectrochemical investigations of stoichiometry and oxidation-reduction potentials of cytochrome c oxidase components in the presence of carbon monoxide: the "invisible" copper.
Topics: Carbon Monoxide; Copper; Cytochrome c Group; Electron Transport Complex IV; Heme; Oxidation-Reduction; Potentiometry; Protein Binding; Spectrophotometry | 1976 |
A re-evaluation of the spectral, potentiometric and energy-linked properties of cytochrome c oxidase in mitochondria.
Topics: Adenosine Triphosphate; Binding Sites; Carbon Monoxide; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cytochromes; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Heme; Mathematics; Mitochondria; Oxidation-Reduction; Potentiometry; Protein Binding; Protein Conformation; Spectrophotometry | 1976 |
Heme a and copper environments in cytochrome oxidase.
Topics: Animals; Binding Sites; Calorimetry; Carbon Monoxide; Cattle; Chloromercuribenzoates; Copper; Dithionite; Electron Transport Complex IV; Heme; Kinetics; Light; Myocardium; Oxidation-Reduction; Protein Binding; Protein Conformation; Spectrophotometry; Thermodynamics | 1976 |
Copper and the oxidation of hemoglobin: a comparison of horse and human hemoglobins.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Copper; Electron Spin Resonance Spectroscopy; Ethylmaleimide; Heme; Hemoglobins; Horses; Humans; Kinetics; Mercury; Oxidation-Reduction; Oxygen Consumption; Rabbits; Sheep; Zinc | 1976 |
Electronic state of heme in cytochrome oxidase. I. Magnetic circular dichroism of the isolated enzyme and its derivatives.
Topics: Animals; Carbon Monoxide; Cattle; Circular Dichroism; Cyanides; Electron Transport Complex IV; Heme; Magnetics; Myocardium; Oxidation-Reduction; Protein Binding; Protein Conformation; Spectrophotometry; Temperature | 1976 |
Low-temperature studies on mixed-valence cytochrome oxidase by using magnetic circular dichroism.
Topics: Carbon Monoxide; Circular Dichroism; Electron Transport Complex IV; Heme; Temperature | 1976 |
Binding of CO to mutant alpha chains of hemoglobin M Iwate; evidence for distal imidazole ligation.
Topics: Carbon Monoxide; Carboxyhemoglobin; Computers; Electron Spin Resonance Spectroscopy; Ferric Compounds; Heme; Hemoglobin M; Hemoglobins, Abnormal; Humans; Imidazoles; Oxidation-Reduction; Phenols; Spectrophotometry | 1977 |
Can heme-CO complexes always be photodissociated?
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Electron Transport Complex IV; Heme; Kinetics; Photolysis; Spectrophotometry; Temperature | 1977 |
A carbon monoxide-binding hemoprotein formed by heme accumulation in Escherichia coli.
Topics: Aerobiosis; Aminolevulinic Acid; Carbon Monoxide; Escherichia coli; Heme; Hemeproteins; Molecular Weight; NAD; Oxidation-Reduction; Protein Binding; Spectrophotometry; Succinates | 1977 |
Low-temperature flash photolysis studies of cytochrome oxidase and its environment.
Topics: Carbon Monoxide; Cold Temperature; Cytochromes; Electron Transport; Electron Transport Complex IV; Heme; In Vitro Techniques; Kinetics; Mitochondria; Models, Biological; Photolysis; Thermodynamics | 1977 |
Studies on the orientations of the mitochondrial redox carriers. I. Orientation of the hemes of cytochrome c oxidase with respect to the plane of a cytochrome oxidase-lipid model membrane.
Topics: Animals; Azides; Carbon Monoxide; Columbidae; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Formates; Freezing; Heme; Lipids; Membranes, Artificial; Mitochondria; Spectrophotometry; Sulfides | 1978 |
Heme c - heme d1 interaction in Pseudomonas cytochrome oxidase (nitrite reductase): a reappraisal of the spectroscopic evidence.
Topics: Ascorbic Acid; Carbon Monoxide; Electron Transport Complex IV; Heme; NADH, NADPH Oxidoreductases; Nitrite Reductases; Oxidation-Reduction; Protein Binding; Pseudomonas; Spectrophotometry | 1978 |
Heme-linked properties of Pseudomonas cytochrome c peroxidase. Evidence for non-equivalence of the hemes.
Topics: Carbon Monoxide; Cytochrome-c Peroxidase; Ferrocyanides; Heme; Hydrogen Peroxide; Kinetics; Ligands; Oxidation-Reduction; Peroxidases; Protein Conformation; Pseudomonas aeruginosa; Spectrophotometry | 1979 |
"Tension" on heme by the proximal base and ligand reactivity: conclusions drawn from model compounds for the reaction of hemoglobin.
Topics: Carbon Monoxide; Heme; Hemoglobins; Kinetics; Ligands; Models, Chemical; Nitric Oxide; Oxygen | 1978 |
Carbon monoxide binding to iron porphyrins.
Topics: Animals; Carbon Monoxide; Heme; Hemeproteins; Humans; Iron; Porphyrins; Solvents; Structure-Activity Relationship | 1979 |
Structure of carboxymyoglobin in crystals and in solution.
Topics: Animals; Carbon Monoxide; Crystallography; Heme; Iron; Ligands; Myoglobin; Protein Conformation; Spectrophotometry, Infrared; Whales | 1979 |
Host heme catabolism in drug-sensitive and drug-resistant malaria.
Topics: Animals; Carbon Monoxide; Chloroquine; Drug Resistance; Heme; Malaria; Male; Mice; Plasmodium berghei | 1977 |
Effect of polyanions on the kinetics of the reaction of apohemoglobin with carbonmonoxy heme.
Topics: Apoproteins; Carbon Monoxide; Heme; Hemoglobins; Humans; Kinetics; Phytic Acid; Protein Binding | 1979 |
NMR studies of P-450 model systems: new structural probes for sulfur-containing hemoproteins.
Topics: Carbon Monoxide; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Heme; Hemeproteins; Magnetic Resonance Spectroscopy; Protein Binding; Protein Conformation | 1979 |
Effect of erythrocyte destruction on the pulmonary excretion rate of carbon monoxide in adult male Wistar rats.
Topics: Animals; Bilirubin; Carbon Monoxide; Erythrocytes; Ethylmaleimide; Heme; Male; Rats; Respiration; Starvation | 1979 |
A correlation of the visible and Soret spectra of dioxygen- and carbon monoxide-heme complexes and five-coordinate heme complexes with the spectra of oxy-, carboxy-, and deoxyhemoglobins.
Topics: Carbon Monoxide; Carboxyhemoglobin; Heme; Hemoglobins; Humans; Oxyhemoglobins; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet | 1979 |
Mercaptide chelated protoheme: a model compound for cytochrome P-450.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Disulfides; Dithionite; Heme; Models, Biological; Spectrophotometry; Sulfhydryl Compounds | 1979 |
Nitric oxide and carbon monoxide equilibria of horse myoglobin and (N-methylimidazole)protoheme. Evidence for steric interaction with the distal residues.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Heme; Horses; Iron; Myocardium; Myoglobin; Nitric Oxide; Protein Binding; Protein Conformation; Spectrophotometry | 1979 |
Accelerated hepatic haem catabolism in the selenium-deficient rat.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Liver; Male; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Porphyrins; Proteins; Rats; Selenium | 1977 |
Loss of haem from cytochrome P-450 caused by lipid peroxidation and 2-allyl-2-isoprophylacetamide. An abnormal pathway not involving production of carbon monoxide.
Topics: Acetamides; Allylisopropylacetamide; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; In Vitro Techniques; Lipid Metabolism; Male; Microsomes, Liver; Peroxides; Rats | 1977 |
Evidence against the binding of native hemoglobin to spectrin of human erythrocytes.
Topics: Azides; Carbon Monoxide; Erythrocytes; Heme; Hemoglobins; Humans; Kinetics; Membrane Proteins; Protein Binding; Spectrin; Spectrometry, Fluorescence; Spectrophotometry | 1978 |
Hydroxylamine oxidoreductase from Nitrosomonas: absorption spectra and content of heme and metal.
Topics: Amino Acids; Carbon Monoxide; Heme; Hydroxylamines; Metals; Nitrosomonas; Oxidation-Reduction; Oxidoreductases; Spectrophotometry | 1978 |
The mechanism of haem degradation in vitro. Kinetic evidence for the formation of a haem-oxygen complex.
Topics: Carbon Monoxide; Heme; Kinetics; Oxidation-Reduction; Oxygen | 1978 |
Principles of ligand binding to heme proteins.
Topics: Carbon Monoxide; Heme; Hemeproteins; Hemoglobins; Kinetics; Ligands; Mathematics; Myoglobin; Oxidation-Reduction; Protein Binding; Protein Conformation; Temperature; Thermodynamics | 1978 |
Heme biosynthesis and drug metabolism in mice with hereditary hemolytic anemia. Heme oxygenase induction as an adaptive response for maintaining cytochrome P-450 in chronic hemolysis.
Topics: Anemia, Hemolytic, Congenital; Animals; Carbon Monoxide; Chronic Disease; Cytochrome P-450 Enzyme System; Female; Heme; Hemolysis; Heterozygote; Homozygote; Hydroxymethylbilane Synthase; Mice; Microsomes, Liver; Mixed Function Oxygenases; Porphobilinogen Synthase; Tissue Distribution | 1979 |
Heme catabolism in liver cirrhosis with portal hypertension after shunt surgery.
Topics: Adult; Aged; Bilirubin; Carbon Monoxide; Female; Heme; Humans; Hypertension, Portal; Liver Cirrhosis; Male; Middle Aged; Renal Veins; Splenic Vein | 1977 |
Effects of cadmium on microsomal hemoproteins and heme oxygenase in rat liver.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Biliverdine; Cadmium; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Heme; In Vitro Techniques; Male; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Rats; Time Factors | 1977 |
Preparation and properties of side-chain cleavage cytochrome P-450 from bovine adrenal cortex by affinity chromatography with pregnenolone as ligand.
Topics: Adrenal Cortex; Adrenal Glands; Animals; Carbon Monoxide; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, Affinity; Cytochrome P-450 Enzyme System; Enzyme Activation; Heme; Mitochondria; Molecular Weight; Oxidoreductases; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Pregnenolone; Spectrophotometry | 1977 |
Effects of chemical modifications of heme on kinetics of carbon monoxide binding to free heme.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Kinetics; Spectrophotometry; Structure-Activity Relationship | 1977 |
Effect of cobalt on synthesis of heme and cytochrome P-450 in the liver. Studies of adult rat hepatocytes in primary monolayer culture and in vivo.
Topics: Aminolevulinic Acid; Aniline Hydroxylase; Animals; Carbon Monoxide; Cells, Cultured; Cobalt; Cytochrome P-450 Enzyme System; Cytochromes; Heme; Liver; Oxidation-Reduction; Protein Binding; Rats; Spectrophotometry | 1976 |
The effect of ligand size and stereochemistry on the reactivity of the alpha and beta chains within hemoglobin.
Topics: Binding Sites; Binding, Competitive; Carbon Monoxide; Cyanides; Heme; Hemoglobins; Humans; Kinetics; Ligands; Macromolecular Substances; Molecular Weight; Nitriles; Phytic Acid; Protein Binding; Protein Conformation | 1976 |
Erythrocyte filterability and heme catabolism during the menstrual cycle.
Topics: Adult; Bilirubin; Blood Cell Count; Carbon Monoxide; Carboxyhemoglobin; Erythrocyte Aging; Erythrocytes; Estrogens; Female; Filtration; Half-Life; Heme; Humans; Menstruation; Progesterone; Reticulocytes | 1976 |
Glucose administration and heme catabolism after caloric restriction.
Topics: Administration, Oral; Adult; Bilirubin; Carbon Monoxide; Diet; Energy Intake; Glucose; Heme; Humans; Hyperbilirubinemia; Infusions, Parenteral; Male | 1976 |
Kinetics of oxygen and carbon monoxide binding to synthetic analogs of the myoglobin and hemoglobin active sites.
Topics: Binding Sites; Carbon Monoxide; Carboxyhemoglobin; Heme; Hemoglobins; Kinetics; Myoglobin; Oxygen; Oxyhemoglobins | 1975 |
Carbon monoxide binding to pentacoordinate mercaptide-heme complexes: kinetic study on models for cytochrome P-450.
Topics: Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Kinetics; Ligands; Models, Chemical; Oxidation-Reduction; Spectrum Analysis; Sulfhydryl Compounds; Thermodynamics | 1976 |
"Early-peak" carbon monoxide production in certain erythropoietic disorders.
Topics: Anemia, Sideroblastic; Blood Platelets; Blood Transfusion; Breath Tests; Carbon Dioxide; Carbon Monoxide; Carbon Radioisotopes; Cell Survival; Chromium Radioisotopes; Erythrocytes; Erythropoiesis; Glycine; Heme; Leukocyte Count; Myeloproliferative Disorders; Time Factors | 1975 |
Reversible oxygenation of protoheme-imidazole complex in aqueous solution (1, 2)
Topics: Binding Sites; Carbon Monoxide; Carboxyhemoglobin; Heme; Imidazoles; Kinetics; Mathematics; Molecular Conformation; Oxidation-Reduction; Oxygen; Photochemistry | 1975 |
Heme catabolism, carbon monoxide production and red cell survival in anemia.
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Anemia, Hemolytic; Anemia, Sideroblastic; Bilirubin; Bone Marrow Cells; Carbon Monoxide; Cell Survival; Erythrocytes; Female; Heme; Humans; Male; Middle Aged; Primary Myelofibrosis; Splenomegaly | 1975 |
Nicotinic acid and the endogenous production of carbon monoxide.
Topics: Adult; Bilirubin; Carbon Monoxide; Chromatography, Gas; Depression, Chemical; Fasting; Female; Heme; Humans; Injections, Intravenous; Male; Nicotinic Acids; Stimulation, Chemical; Time Factors | 1975 |
Reaction of polymer-heme complexes with carbon monoxide or molecular oxygen.
Topics: Binding Sites; Carbon Monoxide; Heme; Kinetics; Lysine; Oxygen; Peptides; Polyethylenes; Povidone; Protein Binding | 1975 |
Mixed type hepatic microsomal enzyme induction by hexachlorobenzene.
Topics: Animals; Carbon Monoxide; Chlorobenzenes; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Female; Half-Life; Heme; Hexachlorobenzene; In Vitro Techniques; Ligands; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Proteins; Rats | 1975 |
Diurnal variation in endogenous production of carbon monoxide. Effect of caloric restriction.
Topics: Adult; Bilirubin; Carbon Monoxide; Circadian Rhythm; Fasting; Heme; Humans; Intracellular Fluid; Male | 1975 |
Circular dichroism studies of myoglobin and leghemoglobin.
Topics: Animals; Apoproteins; Binding Sites; Carbon Monoxide; Circular Dichroism; Cyanides; Glycine max; Heme; Hemeproteins; Leghemoglobin; Myoglobin; Nicotine; Oxidation-Reduction; Oxygen; Protein Binding; Protein Conformation; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet; Whales | 1975 |
Ligand binding properties of horse hemoglobins containing deutero- and mesoheme.
Topics: Animals; Binding Sites; Carbon Monoxide; Heme; Hemoglobins; Horses; Kinetics; Ligands; Oxygen; Protein Binding | 1976 |
Erythropoiesis and carbon monoxide production in Hodgkin's disease.
Topics: Adolescent; Adult; Aged; Anemia; Bone Marrow Examination; Carbon Monoxide; Erythrocyte Aging; Erythropoiesis; Female; Heme; Hodgkin Disease; Humans; Iron; Male; Middle Aged | 1976 |
Carbon monoxide production in patients with breast carcinoma.
Topics: Adult; Aged; Anemia; Breast Neoplasms; Carbon Monoxide; Erythrocyte Aging; Erythropoiesis; Female; Heme; Hemoglobins; Humans; Middle Aged | 1976 |
Kinetic and equilibrium studies of the reactions of heme-substituted horse heart myoglobins with oxygen and carbon monoxide.
Topics: Animals; Binding Sites; Carbon Monoxide; Heme; Horses; Kinetics; Lasers; Mathematics; Myocardium; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet; Temperature | 1976 |
Brain nitric oxide synthase is a haemoprotein.
Topics: Amino Acid Oxidoreductases; Animals; Brain; Carbon Monoxide; Citrulline; Heme; Miconazole; Nitric Oxide; Nitric Oxide Synthase; Potassium Cyanide; Spectrophotometry; Swine | 1992 |
Cloned, expressed rat cerebellar nitric oxide synthase contains stoichiometric amounts of heme, which binds carbon monoxide.
Topics: Amino Acid Oxidoreductases; Amino Acid Sequence; Animals; Carbon Monoxide; Cerebellum; Cloning, Molecular; Heme; Molecular Sequence Data; Nitric Oxide Synthase; Rats; Recombinant Proteins; Spectrum Analysis | 1992 |
Spectroscopic and genetic evidence for two heme-Cu-containing oxidases in Rhodobacter sphaeroides.
Topics: Base Sequence; Blotting, Western; Carbon Monoxide; Cell Membrane; Cloning, Molecular; Copper; Electron Transport Complex IV; Heme; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Rhodobacter sphaeroides; Sequence Alignment; Spectrophotometry, Infrared | 1992 |
Magnetic circular dichroism study of cytochrome ba3 from Thermus thermophilus: spectral contributions from cytochromes b and a3 and nanosecond spectroscopy of CO photodissociation intermediates.
Topics: Carbon Monoxide; Circular Dichroism; Cytochrome b Group; Electron Transport Complex IV; Ferrous Compounds; Heme; Ligands; Magnetics; Models, Chemical; Oxidation-Reduction; Photic Stimulation; Thermus thermophilus | 1992 |
A novel terminal oxidase, cytochrome baa3 purified from aerobically grown Pseudomonas aeruginosa: it shows a clear difference between resting state and pulsed state.
Topics: Carbon Monoxide; Catalysis; Chromatography, Gel; Copper; Cytochrome c Group; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Heme; Molecular Weight; Oxidation-Reduction; Pseudomonas aeruginosa; Spectrophotometry, Ultraviolet; Tetramethylphenylenediamine | 1992 |
Mutagenesis of methionine-183 drastically affects the physicochemical properties of cytochrome c1 of the bc1 complex of Rhodobacter capsulatus.
Topics: Amino Acid Sequence; Base Sequence; Carbon Monoxide; Chemical Phenomena; Chemistry, Physical; Cytochrome b Group; Cytochromes c1; Electrophoresis, Polyacrylamide Gel; Heme; Iron; Methionine; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Restriction Mapping; Rhodobacter capsulatus; Spectrophotometry | 1992 |
Effects of crystallization on the heme-carbon monoxide moiety of bovine heart cytochrome c oxidase carbonyl.
Topics: Animals; Binding Sites; Biophysical Phenomena; Biophysics; Carbon Monoxide; Cattle; Crystallization; Electron Transport Complex IV; Heme; Molecular Structure; Myocardium; Solutions; Spectrophotometry, Infrared | 1992 |
A simple carbon monoxide breath test to estimate erythrocyte turnover.
Topics: Adult; Breath Tests; Carbon Monoxide; Erythrocyte Aging; Female; Heme; Humans; Male; Middle Aged | 1992 |
Resonance Raman investigation of the effects of copper binding to iron-mesoporphyrin.histidine-rich glycoprotein complexes.
Topics: Animals; Binding Sites; Biophysical Phenomena; Biophysics; Blood Proteins; Carbon Monoxide; Copper; Glycoproteins; Heme; In Vitro Techniques; Iron; Mesoporphyrins; Oxidation-Reduction; Photolysis; Proteins; Rabbits; Spectrum Analysis, Raman | 1992 |
The relation of ligand binding to redox state in the hexa-heme nitrite reductase of Wolinella succinogenes.
Topics: Binding Sites; Carbon Monoxide; Heme; Kinetics; Ligands; Nitrite Reductases; Oxidation-Reduction; Photolysis; Spectrum Analysis; Wolinella | 1992 |
Kinetic studies on CO binding to reconstituted myoglobins with four synthetic hemes; structural control in ligand binding to myoglobin.
Topics: Animals; Binding Sites; Carbon Monoxide; Heme; Kinetics; Ligands; Models, Molecular; Myoglobin; Photolysis; Porphyrins; Protein Binding; Protein Conformation; Whales | 1992 |
Ligand binding by the chlorocruorin from Eudistylia vancouverii.
Topics: Animals; Binding Sites; Carbon Monoxide; Heme; Hemeproteins; Kinetics; Ligands; Oxygen; Photolysis; Polychaeta | 1992 |
Conformational change and histidine control of heme chemistry in cytochrome c peroxidase: resonance Raman evidence from Leu-52 and Gly-181 mutants of cytochrome c peroxidase.
Topics: Alkenes; Base Sequence; Carbon Monoxide; Cytochrome-c Peroxidase; DNA Mutational Analysis; Ferric Compounds; Ferrous Compounds; Glycine; Heme; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Leucine; Ligands; Molecular Sequence Data; Oligonucleotides; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Structure-Activity Relationship; Water | 1991 |
A novel aco-type cytochrome-c oxidase from a facultative alkalophilic Bacillus: purification, and some molecular and enzymatic features.
Topics: Bacillus; Carbon Monoxide; Catalysis; Chemical Phenomena; Chemistry, Physical; Chromatography, Ion Exchange; Culture Media; Cyanides; Electron Transport Complex IV; Electrophoresis, Polyacrylamide Gel; Heme; Hydrogen-Ion Concentration; Ligands; Lipids; Molecular Weight; Staining and Labeling | 1990 |
Functional reconstitution of cytochrome P-450scc with hemin activated with Woodward's reagent K. Formation of a hemeprotein cross-link.
Topics: Amino Acid Sequence; Apoenzymes; Binding Sites; Carbon Monoxide; Cholesterol Side-Chain Cleavage Enzyme; Chromatography, Gel; Cross-Linking Reagents; Heme; Hemeproteins; Isoxazoles; Kinetics; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Spectrophotometry | 1992 |
Alteration of the proximal bond energy in the unliganded form of the homodimeric myoglobin from Nassa mutabilis. Kinetic and spectroscopic evidence.
Topics: Animals; Carbon Monoxide; Heme; Hydrogen-Ion Concentration; Kinetics; Ligands; Myoglobin; Protein Conformation; Sequence Homology, Nucleic Acid; Snails; Spectrum Analysis, Raman | 1992 |
Neutron diffraction study of carbonmonoxymyoglobin.
Topics: Amino Acid Sequence; Binding Sites; Carbon Monoxide; Crystallization; Fourier Analysis; Heme; Mathematics; Models, Molecular; Molecular Sequence Data; Myoglobin; Neutrons; Protein Conformation; Scattering, Radiation | 1991 |
Activation of soluble guanylate cyclase by carbon monoxide and inhibition by superoxide anion.
Topics: Blood Platelets; Carbon Monoxide; Enzyme Activation; Guanylate Cyclase; Heme; Humans; Nitrogen Oxides; Nitroprusside; Superoxide Dismutase; Superoxides | 1990 |
Allosteric transition in triply met-haemoglobin.
Topics: Allosteric Regulation; Carbon Monoxide; Heme; Humans; In Vitro Techniques; Methemoglobin; Oxidation-Reduction; Oxygen; Phytic Acid; Structure-Activity Relationship | 1991 |
Contributions of residue 45(CD3) and heme-6-propionate to the biomolecular and geminate recombination reactions of myoglobin.
Topics: Animals; Binding, Competitive; Carbon Monoxide; Heme; Hydrogen-Ion Concentration; Kinetics; Mutation; Myoglobin; Nitrogen Oxides; Oxygen; Protein Conformation; Swine; Whales | 1991 |
The heme groups of cytochrome o from Escherichia coli.
Topics: Carbon Monoxide; Cell Membrane; Cytochrome b Group; Cytochromes; Dithionite; Escherichia coli; Escherichia coli Proteins; Heme; Oxidation-Reduction; Spectrophotometry | 1991 |
Electron spin resonance studies of wild-type and mutant cytochromes P-450d: effects of mutations at proximal, aromatic and distal sites on g values.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; DNA Mutational Analysis; Electron Spin Resonance Spectroscopy; Heme; Microsomes, Liver; Rats; Structure-Activity Relationship | 1990 |
Ligand binding and structural perturbations in cytochrome c peroxidase. A crystallographic study.
Topics: Carbon Monoxide; Cyanides; Cytochrome-c Peroxidase; Fluorides; Heme; Hydrogen Bonding; Ligands; Models, Molecular; Nitric Oxide; Peroxidases; Protein Binding; Protein Conformation; Saccharomyces cerevisiae; X-Ray Diffraction | 1990 |
Heme-copper and heme-heme interactions in the cytochrome bo-containing quinol oxidase of Escherichia coli.
Topics: Carbon Monoxide; Cell Membrane; Copper; Cytochrome b Group; Cytochromes; Electron Spin Resonance Spectroscopy; Escherichia coli; Escherichia coli Proteins; Heme; Hydrogen-Ion Concentration; Oxidation-Reduction; Oxidoreductases | 1990 |
CO recombination in cytochrome c peroxidase: effect of the local heme environment on CO binding explored through site-directed mutagenesis.
Topics: Binding Sites; Carbon Monoxide; Cloning, Molecular; Cytochrome-c Peroxidase; Escherichia coli; Genes; Heme; Hydrogen-Ion Concentration; Kinetics; Mathematics; Models, Theoretical; Mutation; Peroxidases; Protein Binding; Recombinant Proteins; Spectrophotometry | 1990 |
Expression of cyoA and cyoB demonstrates that the CO-binding heme component of the Escherichia coli cytochrome o complex is in subunit I.
Topics: Blotting, Western; Carbon Monoxide; Cell Membrane; Chromatography, High Pressure Liquid; Copper; Cytochrome b Group; Electron Transport Complex IV; Escherichia coli; Gene Expression; Heme; Macromolecular Substances; Plasmids; Restriction Mapping; Spectrophotometry | 1990 |
The effect of haem ligands on the redox states of the hexa-haem nitrite reductase from Wolinella succinogenes.
Topics: Bacteroidaceae; Binding Sites; Carbon Monoxide; Circular Dichroism; Dithionite; Electron Spin Resonance Spectroscopy; Heme; Kinetics; Nitrite Reductases; Oxidation-Reduction; Sodium Cyanide; Spectrophotometry; Thermodynamics | 1990 |
CO dissociation in cytochrome c peroxidase: site-directed mutagenesis shows that distal Arg 48 influences CO dissociation rates.
Topics: Arginine; Binding Sites; Carbon Monoxide; Cytochrome-c Peroxidase; Fungal Proteins; Heme; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Saccharomyces cerevisiae | 1990 |
Potentiometric and spectroscopic properties of the cytochrome o complex of Escherichia coli.
Topics: Carbon Monoxide; Cytochrome b Group; Cytochromes; Escherichia coli; Escherichia coli Proteins; Ferricyanides; Heme; Hydroxyquinolines; Kinetics; Oxidation-Reduction; Potentiometry; Spectrophotometry | 1990 |
Heme-CO as a probe of the conformational state of calmodulin.
Topics: Animals; Brain; Calmodulin; Carbon Monoxide; Heme; Kinetics; Protein Binding; Protein Conformation; Spectrophotometry; Swine | 1990 |
Stereochemistry of carbon monoxide binding to normal human adult and Cowtown haemoglobins.
Topics: Carbon Monoxide; Carboxyhemoglobin; Crystallography; Heme; Hemoglobins; Hemoglobins, Abnormal; Humans; Structure-Activity Relationship | 1990 |
Carbon monoxide production by nonbacterial sources after heme feeding of neonatal rats.
Topics: Administration, Oral; Ampicillin; Analysis of Variance; Animals; Animals, Newborn; Carbon Monoxide; Heme; Intestinal Mucosa; Kanamycin; Metalloporphyrins; Rats; Rats, Inbred Strains | 1990 |
Zinc protoporphyrin administration for suppression of increased bilirubin production by iatrogenic hemolysis in rhesus neonates.
Topics: Animals; Animals, Newborn; Bilirubin; Carbon Monoxide; Erythrocytes; Heme; Heme Oxygenase (Decyclizing); Hemolysis; Humans; Infant, Newborn; Jaundice, Neonatal; Macaca mulatta; Mixed Function Oxygenases; Porphyrins; Protoporphyrins | 1990 |
Transmembrane movement of heme.
Topics: Apoproteins; Carbon Monoxide; Dimyristoylphosphatidylcholine; Heme; Kinetics; Lipid Bilayers; Mathematics; Models, Biological; Myoglobin; Organophosphates; Phosphatidylcholines | 1990 |
The effects of lipid composition on the rate and extent of heme binding to membranes.
Topics: Carbon Monoxide; Cholesterol; Dimyristoylphosphatidylcholine; Heme; Kinetics; Liposomes; Mathematics; Models, Biological; Organophosphates; Phosphatidylcholines; Structure-Activity Relationship; Thermodynamics | 1990 |
Heme catabolism in rhesus neonates inhibited by zinc protoporphyrin.
Topics: Animals; Animals, Newborn; Bilirubin; Blood Gas Analysis; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Indicators and Reagents; Liver; Macaca mulatta; Porphyrins; Protoporphyrins | 1990 |
Suicide inactivation of cytochrome P-450 by methoxsalen. Evidence for the covalent binding of a reactive intermediate to the protein moiety.
Topics: Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Heme; Kinetics; Methoxsalen; Microsomes, Liver; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Precipitin Tests; Protein Binding; Rats; Rats, Inbred Strains; Spectrum Analysis; Ultraviolet Rays | 1989 |
Integer-spin electron paramagnetic resonance of iron proteins.
Topics: Binding Sites; Carbon Monoxide; Crystallization; Edetic Acid; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Heme; Iron; Magnetics; Metalloproteins; Models, Biological; Myoglobin; Protein Conformation; Temperature | 1989 |
Preparation and spectral characterization of the heme d1.apomyoglobin complex: an unusual protein environment for the substrate-binding heme of Pseudomonas cytochrome oxidase.
Topics: Apoproteins; Carbon Monoxide; Cyanides; Dithionite; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Heme; Ligands; Myoglobin; Oxidation-Reduction; Protein Binding; Pseudomonas; Solutions; Spectrophotometry | 1989 |
Alkyl and aromatic isocyanide binding to haem complexes.
Topics: Carbon Monoxide; Cyanides; Heme; Imidazoles; Myoglobin; Nitriles; Protein Binding; Spectrophotometry; Tosyl Compounds | 1989 |
Effect of the distal histidine modification (Cyanation) of myoglobin on the ligand binding kinetics and the heme environmental structures.
Topics: Animals; Carbon Monoxide; Cyanogen Bromide; Heme; Histidine; Ligands; Male; Myoglobin; Spermatozoa; Thermodynamics; Whales | 1989 |
Crystal structure of the carbon monoxide-substrate-cytochrome P-450CAM ternary complex.
Topics: Camphor; Camphor 5-Monooxygenase; Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Ligands; Mixed Function Oxygenases; Models, Chemical; Molecular Sequence Data; Oxygen; Protein Conformation; X-Ray Diffraction | 1989 |
Carbon monoxide excretion as an index of bilirubin production in rhesus monkeys.
Topics: Animals; Animals, Newborn; Bilirubin; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Hemolysis; Hyperbilirubinemia; Macaca; Macaca mulatta; Metalloporphyrins; Protoporphyrins | 1989 |
Structural characterization of nitrimyoglobin.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Horses; Ligands; Magnetic Resonance Spectroscopy; Metmyoglobin; Myoglobin; Nitrites; Oxygen; Spectrum Analysis | 1989 |
Flash photolysis of the serum albumin-heme-CO complex.
Topics: Binding Sites; Carbon Monoxide; Heme; Kinetics; Photolysis; Serum Albumin; Spectrophotometry | 1989 |
Charge motion in MbCO crystals after flash photolysis.
Topics: Carbon Monoxide; Crystallization; Electrochemistry; Heme; Iron; Myoglobin; Photolysis | 1989 |
Cytochrome c peroxidase mutant active site structures probed by resonance Raman and infrared signatures of the CO adducts.
Topics: Arginine; Binding Sites; Carbon Monoxide; Cytochrome-c Peroxidase; DNA Mutational Analysis; Heme; Histidine; Hydrogen Bonding; Peroxidases; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae; Spectrophotometry, Infrared; Spectrum Analysis, Raman | 1988 |
Endothelium-derived relaxing factor from pulmonary artery and vein possesses pharmacologic and chemical properties identical to those of nitric oxide radical.
Topics: Acetylcholine; Animals; Biological Products; Bradykinin; Carbon Monoxide; Cattle; Cyclic GMP; Endothelium, Vascular; Free Radicals; Guanylate Cyclase; Heme; Metalloporphyrins; Muscle Relaxation; Muscle, Smooth, Vascular; Myoglobin; Nitric Oxide; Oxyhemoglobins; Pulmonary Artery; Pulmonary Veins; Pyrogallol; Superoxide Dismutase | 1987 |
CO production by feces and urine.
Topics: Animals; Carbon Monoxide; Feces; Heme; Humans; Male; Mice; Mineral Oil; Rats; Sulfites; Urine | 1989 |
Chromatium flavocytochrome c: kinetics of reduction of the heme subunit, and the flavocytochrome c-mitochondrial cytochrome c complex.
Topics: Animals; Bacteria; Carbon Monoxide; Chromatium; Chromatography, Gel; Cytochrome c Group; Flavin Mononucleotide; Flavins; Heme; Horses; Mitochondria, Heart; Oxidation-Reduction; Protein Binding; Spectrophotometry | 1985 |
Liposome-embedded iron-porphyrins as an artificial oxygen-carrier.
Topics: Blood Substitutes; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Heme; Liposomes; Magnetic Resonance Spectroscopy; Oxygen; Thermodynamics | 1985 |
Transient Raman study of horseradish peroxidase. Evidence for a lack of extensive heme pocket relaxation subsequent to carbon monoxide photolysis.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Electron Transport Complex IV; Heme; Hemoglobins; Horseradish Peroxidase; Kinetics; Myocardium; Myoglobin; Peroxidases; Protein Binding; Protein Conformation; Spectrum Analysis, Raman; Structure-Activity Relationship | 1985 |
Comparison of heme environments and proximal ligands in peroxidases and other hemoproteins through carbon-13 nuclear magnetic resonance spectroscopy of carbon monoxide complexes.
Topics: Carbon Monoxide; Chloride Peroxidase; Cysteine; Cytochrome-c Peroxidase; Heme; Hemeproteins; Histidine; Horseradish Peroxidase; Imidazoles; Isoenzymes; Lactoperoxidase; Magnetic Resonance Spectroscopy; Myoglobin; Peroxidases | 1985 |
Transient resonance Raman spectroscopy shows unrelaxed heme following CO photodissociation from cytochrome-c peroxidase.
Topics: Carbon Monoxide; Cytochrome-c Peroxidase; Heme; Peroxidases; Photolysis; Protein Binding; Protein Conformation; Spectrum Analysis, Raman | 1986 |
Electron flow and heme-heme interaction between cytochromes b-558, b-595 and d in a terminal oxidase of Escherichia coli.
Topics: Bacterial Proteins; Carbon Monoxide; Cytochrome b Group; Cytochromes; Cytochromes a1; Electron Spin Resonance Spectroscopy; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Multienzyme Complexes; NADPH Oxidases; Oxidation-Reduction; Oxidoreductases; Oxygen; Protein Binding; Ubiquinone | 1987 |
Kinetic evidence for a role of heme geometry on the modulation of carbon monoxide reactivity in human hemoglobin.
Topics: Carbon Monoxide; Carboxyhemoglobin; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Kinetics; Protein Conformation | 1988 |
The mechanism of the suicidal, reductive inactivation of microsomal cytochrome P-450 by carbon tetrachloride.
Topics: Animals; Biotransformation; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Hydrocarbons; Kinetics; Male; Methane; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Inbred Strains | 1988 |
Effect of solvent, pressure and temperature on reaction rates of the multiheme hydroxylamine oxidoreductase. Evidence for conformational change.
Topics: Carbon Monoxide; Ethylene Glycols; Heme; Hydrostatic Pressure; Kinetics; Nitrosomonas; Oxidation-Reduction; Oxidoreductases; Protein Conformation; Solvents; Temperature; Thermodynamics; Water | 1988 |
Metastable photoproducts from carbon monoxide myoglobin.
Topics: Animals; Carbon Monoxide; Freezing; Heme; Light; Myoglobin; Photochemistry; Protein Conformation; Spectrum Analysis, Raman | 1986 |
Energy barriers in binding of carbon monoxide and oxygen to heme model compounds.
Topics: Carbon Monoxide; Heme; Models, Biological; Models, Molecular; Molecular Conformation; Oxygen; Porphyrins; Thermodynamics | 1987 |
Proof that Sn-protoporphyrin inhibits the enzymatic catabolism of heme in vivo. Suppression of 14CO generation from radiolabeled endogenous and exogenous heme sources.
Topics: Aminolevulinic Acid; Animals; Carbon Monoxide; Heme; Hemin; Metalloporphyrins; Oxidation-Reduction; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains | 1987 |
Functional consequences of haem orientational disorder in sperm-whale and yellow-fin-tuna myoglobins.
Topics: Animals; Carbon Monoxide; Cetacea; Fishes; Heme; Kinetics; Ligands; Myoglobin; Oxygen; Photolysis; Protein Binding; Protein Conformation; Stereoisomerism; Structure-Activity Relationship; Tuna; Whales | 1987 |
Low- and ultralow-temperature magnetic circular dichroism studies of reduced cytochromes P-450-LM2 and P-420-LM2 and of photo-products of their co-complexes. The spin-state and axial ligation of heme iron.
Topics: Animals; Carbon Monoxide; Circular Dichroism; Cytochrome P-450 Enzyme System; Heme; Isoenzymes; Microsomes, Liver; Photochemistry; Photolysis; Rabbits | 1987 |
Carbon monoxide generation from tin- and zinc-protoporphyrin by tissue homogenates.
Topics: Animals; Carbon Monoxide; Female; Heme; Intestinal Mucosa; Kidney; Kinetics; Liver; Metalloporphyrins; Organ Specificity; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Spleen | 1987 |
Protoheme-carbon monoxide geminate kinetics.
Topics: Carbon Monoxide; Ethylene Glycol; Ethylene Glycols; Glycerol; Heme; Kinetics; Lasers; Mathematics; Models, Biological; Photolysis | 1986 |
Resonance Raman investigation of CO-ligated monomeric insect hemoglobins. Direct evidence for reciprocal changes in iron-axial ligand bonds induced by allosteric transitions.
Topics: Allosteric Regulation; Animals; Carbon Monoxide; Carboxyhemoglobin; Chironomidae; Heme; Hemoglobins; Hydrogen-Ion Concentration; Protein Binding; Spectrum Analysis, Raman | 1986 |
Postmortem formation of carbon monoxide by bacteria.
Topics: Adult; Bacteria; Carbon Monoxide; Drowning; Heme; Hemeproteins; Humans; Male; Postmortem Changes | 1986 |
Functional effects of heme orientational disorder in sperm whale myoglobin.
Topics: Animals; Carbon Monoxide; Circular Dichroism; Heme; Kinetics; Molecular Conformation; Myoglobin; Oxygen; Spectrophotometry; Whales | 1987 |
Interspecies variations in the transient heme species generated subsequent to CO photolysis from hemoglobins.
Topics: Amphibians; Animals; Carbon Monoxide; Fishes; Heme; Hemoglobins; Humans; Mammals; Photolysis; Reptiles; Species Specificity; Spectrum Analysis, Raman | 1987 |
Formation of aryl and aryldiazenyl complexes in reactions of arylhydrazines and aryldiazenes with a synthetic model compound of haemoprotein.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Chlorides; Heme; Imines; Macromolecular Substances; Models, Chemical; Oxygen; Phenylhydrazines; Potassium Cyanide | 1986 |
Resonance Raman studies of dioxygen and carbon monoxide binding to imidazole-appended hemes.
Topics: Carbon Monoxide; Heme; Imidazoles; Oxygen; Spectrum Analysis, Raman; Structure-Activity Relationship | 1987 |
Tin protoporphyrin inhibits carbon monoxide production in adult mice.
Topics: Animals; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Metalloporphyrins; Mice; Mixed Function Oxygenases; Porphyrins; Protoporphyrins | 1985 |
Effect of tin protoporphyrin on the excretion rate of carbon monoxide in newborn rats after hematoma formation.
Topics: Animals; Animals, Newborn; Bilirubin; Carbon Monoxide; Hematoma; Heme; Heme Oxygenase (Decyclizing); Humans; Infant, Newborn; Jaundice, Neonatal; Liver; Metalloporphyrins; Mixed Function Oxygenases; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Spleen | 1985 |
Molecular dynamics simulation of photodissociation of carbon monoxide from hemoglobin.
Topics: Animals; Carbon Monoxide; Heme; Hemoglobins; Humans; Iron; Photolysis | 1985 |
Heme transfer between phospholipid membranes and uptake by apohemoglobin.
Topics: Apoproteins; Carbon Monoxide; Heme; Hemoglobins; Humans; Kinetics; Lipid Bilayers; Liposomes; Mathematics; Membrane Lipids; Phospholipids; Spectrophotometry | 1985 |
The vibrational bands of carbon monoxide bound to hemes or metal surfaces.
Topics: Carbon Monoxide; Heme; Metals; Oxidation-Reduction; Spectrophotometry, Infrared; Surface Properties; Vibration | 1985 |
Heme-modification studies of myoglobin. II. Ligand binding characteristics of ferric and ferrous myoglobins containing unnatural hemes.
Topics: Animals; Azides; Carbon Monoxide; Chemical Phenomena; Chemistry; Computers; Esters; Ferredoxins; Glucosephosphate Dehydrogenase; Heme; Horses; Hydrogen-Ion Concentration; Iron; Ligands; Luminescent Measurements; Metalloproteins; Methylation; Myocardium; Myoglobin; NADH, NADPH Oxidoreductases; Oxidation-Reduction; Oxygen; Plants; Protein Binding; Spectrophotometry; Structure-Activity Relationship | 1973 |
Reduced nicotinamide adenine dinucleotide phosphate-sulfite reductase of enterobacteria. VI. The reaction of carbon monoxide with the Escherichia coli holoenzyme, the hemoprotein, and free siroheme.
Topics: Carbon Monoxide; Enterobacteriaceae; Escherichia coli; Flavoproteins; Heme; Hemeproteins; Iron; Kinetics; Mathematics; NADP; Oscillometry; Oxidation-Reduction; Oxidoreductases; Photolysis; Porphyrins; Spectrophotometry; Structure-Activity Relationship; Sulfites | 1974 |
Endogenous formation of carbon monoxide and methane at elevated pressure.
Topics: Atmosphere Exposure Chambers; Atmospheric Pressure; Bacteria; Carbon Monoxide; Carboxyhemoglobin; Diving; Ecological Systems, Closed; Environment, Controlled; Helium; Heme; Intestines; Methane; Oxygen; Partial Pressure; Submarine Medicine | 1974 |
Preparation and properties of partially purified cytochrome P-450 and reduced nicotinamide adenine dinucleotide phosphate-cytochrome P-450 reductase from rabbit liver microsomes.
Topics: Animals; Binding Sites; Carbon Monoxide; Centrifugation, Density Gradient; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Detergents; Dithionite; Electrophoresis, Disc; Electrophoresis, Polyacrylamide Gel; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Heme; Kinetics; Male; Microsomes, Liver; Mixed Function Oxygenases; Molecular Weight; NADP; Oxidation-Reduction; Phospholipids; Polyethylene Glycols; Protein Binding; Rabbits; Solubility; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfides | 1974 |
Sequence of the reaction of heme catabolism catalyzed by the microsomal heme oxygenase system.
Topics: Animals; Carbon Monoxide; Cytochrome Reductases; Heme; Hydrogen-Ion Concentration; Microsomes; Microsomes, Liver; NADP; Oxidation-Reduction; Oxygenases; Protein Binding; Spectrophotometry; Spleen; Swine; Thiosulfates; Time Factors | 1974 |
Effect of oxygen on heme and cytochrome content in some facultative bacteria.
Topics: Aerobiosis; Anaerobiosis; Bacillus; Bacillus cereus; Carbon Monoxide; Cytochromes; Escherichia coli; Glucose; Heme; Levulinic Acids; Oxidation-Reduction; Oxygen; Pseudomonas aeruginosa; Sarcina; Species Specificity; Spectrophotometry; Staphylococcus; Time Factors | 1973 |
Studies on cytochrome oxidase. 3. Ligand reactions and Schiff base formation of heme a.
Topics: Borates; Carbon Monoxide; Chemical Phenomena; Chemistry; Electron Transport Complex IV; Globins; Heme; Imines; Peptides; Spectrophotometry | 1967 |
Studies on cytochrome c peroxidase. XII. Crystalline synthetic enzymes containing unnatural heme prosthetic groups.
Topics: Azides; Carbon Monoxide; Chemical Phenomena; Chemistry; Crystallization; Cyanides; Cytochromes; Electron Spin Resonance Spectroscopy; Fluorides; Heme; Iron Isotopes; Peroxidases; Spectrum Analysis | 1968 |
Studies on cytochrome oxidase. IV. Optical rotatory dispersion of hematin a.
Topics: Carbon Monoxide; Chromatography, Thin Layer; Electron Transport Complex IV; Heme; Optical Rotatory Dispersion; Spectrum Analysis; Ultracentrifugation | 1969 |
Hemoproteins in anaerobically grown yeast cells.
Topics: Carbon Monoxide; Cytochromes; Electron Transport Complex IV; Heme; Oxygen; Pigments, Biological; Proteins; Saccharomyces; Spectrophotometry | 1969 |
Conformational evidence for the non-identity of cytochromes a and a3 in cytochrome oxidase.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Cytochromes; Electron Transport Complex IV; Ferricyanides; Heme; Spectrum Analysis | 1969 |
A study on some spectral properties of P-450 in a submicrosomal particle.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Cytochromes; Electron Spin Resonance Spectroscopy; Heme; Liver; Microsomes; Nitric Oxide; Oxidation-Reduction; Phenobarbital; Proteins; Rabbits; Spectrophotometry | 1969 |
The haem--protein interaction in cytochrome P-450.
Topics: Carbon Monoxide; Cytochromes; Electron Spin Resonance Spectroscopy; Heme; Iron; Magnetic Resonance Spectroscopy; Nitric Oxide; Protein Binding; Spectrum Analysis | 1969 |
Studies on cytochrome c peroxidase. XVI. Recombination of apoenzyme with spin-labeled protoheme.
Topics: Azides; Carbon Monoxide; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Thin Layer; Cyanides; Cyclic N-Oxides; Cytochromes; Electron Spin Resonance Spectroscopy; Ferrocyanides; Fluorides; Free Radicals; Heme; Hydrogen Peroxide; Kinetics; Methods; Peroxidases; Protein Binding; Pyrrolidines; Spectrophotometry | 1969 |
CO as a ligand of photosensitive P-630 transformed from horseradish peroxidase in the presence of indole-3-acetic acid.
Topics: Carbon Monoxide; Cyanides; Darkness; Electron Spin Resonance Spectroscopy; Heme; Indoleacetic Acids; Light; Models, Chemical; Oxidation-Reduction; Oxygen Consumption; Peroxidases; Plant Proteins; Plants; Radiation Effects; Spectrophotometry | 1970 |
Carbon monoxide binding studies of cytochrome a3 hemes in intact rat liver mitochondria.
Topics: Adenosine Triphosphate; Aniline Compounds; Animals; Ascorbic Acid; Binding Sites; Carbon Monoxide; Cytochromes; Electron Transport; Glutamates; Helium; Heme; Hydrogen-Ion Concentration; Malates; Membrane Potentials; Mitochondria, Liver; NAD; Oxidation-Reduction; Oxygen; Rats; Spectrophotometry; Succinates; Thermodynamics; Uncoupling Agents | 1971 |
Studies on the stability of oxyhemoglobin A and its constituent chains and their derivatives.
Topics: Benzoates; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Dialysis; Drug Stability; Electron Spin Resonance Spectroscopy; Ferricyanides; Globins; Heme; Hemoglobins; Hemoglobins, Abnormal; Humans; Iron; Mercury; Methemoglobin; Organometallic Compounds; Oxidation-Reduction; Oxygen; Peptides; Photolysis; Protein Denaturation; Salicylates; Spectrophotometry; Urea | 1971 |
Oxidation state dependent circular dichroic behavior of cytochrome oxidase in the 600 nm region.
Topics: Animals; Bile Acids and Salts; Carbon Monoxide; Cattle; Circular Dichroism; Copper; Cyanides; Cytochromes; Drug Stability; Electron Transport Complex IV; Heme; Iron; Myocardium; Oxidation-Reduction; Spectrophotometry; Sulfites; Temperature; Time Factors | 1970 |
Some spectral properties of the human hemoglobin-haptoglobin complex.
Topics: Adult; Aerobiosis; Carbon Monoxide; Chemical Phenomena; Chemistry; Circular Dichroism; Electron Spin Resonance Spectroscopy; Globins; Haptoglobins; Heme; Hemoglobins; Humans; Oxidation-Reduction; Oxygen; Protein Binding; Pyridines; Spectrophotometry; Sulfites; Ultraviolet Rays | 1971 |
The oxidation-reduction potentials of the hemes and copper of cytochrome oxidase from beef heart.
Topics: Ammonium Sulfate; Animals; Carbon Monoxide; Cattle; Chemical Phenomena; Chemical Precipitation; Chemistry; Copper; Cytochromes; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Ferricyanides; Heme; Myocardium; NAD; Oxidation-Reduction; Phenazines; Potentiometry; Spectrophotometry; Sulfuric Acids | 1971 |
Ethyl isocyanide complexes of bacterial cytochrome P-450.
Topics: Bacterial Proteins; Binding Sites; Camphor; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Cytochromes; Electron Spin Resonance Spectroscopy; Heme; Hydrogen-Ion Concentration; Iron; Kinetics; Oxidation-Reduction; Potassium Chloride; Protein Binding; Pseudomonas; Spectrophotometry; Sulfites | 1971 |
Carbon monoxide bonding in hemeproteins.
Topics: Binding Sites; Carbon Monoxide; Cytochromes; Electron Transport Complex IV; Heme; Hemoglobins; Histidine; Infrared Rays; Iron; Ketones; Myoglobin; Oxygen; Protein Binding; Proteins; Spectrum Analysis | 1970 |
Purification and some properties of cytochrome c oxidase from the yeast Saccharomyces cerevisiae.
Topics: Ammonium Sulfate; Animals; Carbon Monoxide; Cattle; Centrifugation, Density Gradient; Chemical Precipitation; Chromatography, Gel; Cyanides; Detergents; Electron Transport Complex IV; Electrophoresis; Heme; Hydrogen Peroxide; Kinetics; Macromolecular Substances; Molecular Weight; Myocardium; Oxidation-Reduction; Saccharomyces; Saccharomyces cerevisiae; Spectrophotometry; Sulfites; Sulfuric Acids; Urea | 1971 |
The kinetics of the reactions of leghemoglobin with oxygen and carbon monoxide.
Topics: Acetates; Carbon Monoxide; Chromatography, Gel; Chromatography, Ion Exchange; Diphosphates; Glycine max; Heme; Hydrogen-Ion Concentration; Kinetics; Oxygen; Plant Proteins; Protein Binding; Species Specificity; Spectrophotometry; Temperature | 1972 |
Heme-heme interaction in cytochrome oxidase.
Topics: Animals; Azides; Carbon Monoxide; Columbidae; Cytochromes; Electron Transport; Electron Transport Complex IV; Ferricyanides; Heart; Heme; Hydrogen-Ion Concentration; Mathematics; Mitochondria, Muscle; Myocardium; NAD; Oxidation-Reduction; Potentiometry; Spectrophotometry | 1972 |
Heme-heme interaction in cytochrome c oxidase in situ as measured by EPR spectroscopy.
Topics: Aerobiosis; Anaerobiosis; Animals; Azides; Carbon Monoxide; Chemical Phenomena; Chemistry; Cold Temperature; Columbidae; Copper; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Heart; Heme; Membranes; Mitochondria, Muscle; Myocardium; Oxidation-Reduction; Potentiometry | 1972 |
Soluble cytochrome b 5 from human erythrocytes.
Topics: Animals; Carbon Monoxide; Cattle; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cytochromes; Electron Spin Resonance Spectroscopy; Electrophoresis, Disc; Erythrocytes; Heme; Humans; Microsomes, Liver; Molecular Weight; NAD; Oxidation-Reduction; Oxidoreductases; Rabbits; Rats; Reticulocytes; Spectrophotometry; Sulfites; Ultracentrifugation | 1972 |
Heme-heme interactions in cytochrome c oxidase: effects of photodissociation of the CO compound.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cold Temperature; Columbidae; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Heme; Light; Mitochondria, Muscle; Myocardium; Oxidation-Reduction; Photolysis; Protein Binding; Radiation Effects | 1972 |
Studies on cytochrome oxidase. IX. Heme-copper interaction.
Topics: Animals; Carbon Monoxide; Cattle; Copper; Cyanides; Cytochromes; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Ferricyanides; Heme; Models, Chemical; Myocardium; Oxidation-Reduction; Protein Binding; Spectrophotometry, Infrared | 1972 |
Myeloperoxidase of the leukocyte of normal blood. V. The spectral conversion of myeloperoxidase to a cytochrome oxidase like derivative.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Dialysis; Electron Transport Complex IV; Heme; Hydrochloric Acid; Hydrogen-Ion Concentration; Kinetics; Leukocytes; Oxidation-Reduction; Peroxidases; Protein Binding; Spectrophotometry; Swine | 1972 |
Photo- and thermochromism of cytochrome oxidase: significance of a new photodissociable species.
Topics: Carbon Monoxide; Cyanates; Electron Transport Complex IV; Heme; Hydrogen-Ion Concentration; Ligands; Nitrogen; Oxidation-Reduction; Photochemistry; Photolysis; Protein Conformation; Spectrum Analysis; Temperature | 1972 |
Carbon monoxide production from heme compounds by bacteria.
Topics: Aerobiosis; Anaerobiosis; Animals; Bacillus cereus; Bilirubin; Carbon Monoxide; Chromatography, Gas; Copper; Cytochrome c Group; Erythrocytes; Hematoporphyrins; Heme; Hemoglobins; Hemolysis; Iron; Myoglobin; Porphyrins; Sheep; Streptococcus | 1972 |
Solubilization and purification of cytochrome 1 from Nitrosomonas.
Topics: Acetone; Ammonium Sulfate; Azides; Carbon Monoxide; Chemical Precipitation; Cholic Acids; Cyanides; Cytochromes; Electron Transport Complex IV; Enzyme Activation; Ethyl Ethers; Heme; Nitrosomonas; Oxidation-Reduction; Potassium Chloride; Pyridines; Solubility; Spectrophotometry; Sulfides; Surface-Active Agents; Time Factors | 1972 |
Anomalous ligand binding by a class of high spin c-type cytochromes.
Topics: Binding Sites; Carbon Isotopes; Carbon Monoxide; Chemical Phenomena; Chemistry; Chromatium; Cytochrome c Group; Heme; Kinetics; Ligands; Light; Mathematics; Models, Chemical; Molecular Weight; Photolysis; Protein Binding; Pseudomonas; Rhodobacter sphaeroides; Rhodopseudomonas; Rhodospirillum rubrum; Species Specificity; Spectrophotometry | 1973 |
Heme modification studies of myoglobin. I. Purification and some optical and EPR characteristics of synthesized myoglobins containing unnatural hemes.
Topics: Animals; Apoproteins; Azides; Carbon Monoxide; Chemical Phenomena; Chemistry; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cold Temperature; Cyanides; Deuterium; Electron Spin Resonance Spectroscopy; Fluorides; Heme; Horses; Hydrogen Peroxide; Ligands; Myocardium; Myoglobin; Oxidation-Reduction; Oxygen; Spectrophotometry | 1973 |
Cytochrome oxidase from Pseudomonas aeruginosa. I. Reaction with copper protein.
Topics: Anaerobiosis; Bacterial Proteins; Binding Sites; Carbon Monoxide; Computers; Copper; Electron Transport; Electron Transport Complex IV; Heme; Kinetics; Mathematics; Oxidation-Reduction; Protein Binding; Pseudomonas aeruginosa; Spectrophotometry; Thermodynamics | 1973 |
Purification and properties of Ascaris cytochrome b 560.
Topics: Amino Acids; Ammonium Sulfate; Animals; Ascaris; Carbon Monoxide; Chromatography, Gel; Chromatography, Ion Exchange; Cytochrome c Group; Cytochromes; Heme; Hydrogen-Ion Concentration; Molecular Weight; Muscles; Oxidation-Reduction; Protein Binding; Pyridines; Spectrophotometry; Spectrophotometry, Ultraviolet; Temperature | 1973 |
Hemoglobin Abraham Lincoln, beta32 (B14) leucine leads to proline. An unstable variant producing severe hemolytic disease.
Topics: Adult; Amino Acids; Anemia, Hemolytic; Carbon Isotopes; Carbon Monoxide; Chemical Precipitation; Chromatography, Ion Exchange; Chromium Isotopes; Electrophoresis; Erythrocytes; Female; Half-Life; Heme; Hemoglobins, Abnormal; Hot Temperature; Humans; Hydroxymercuribenzoates; Inclusion Bodies; Leucine; Methemoglobin; Proline; Reticulocytes; Sulfites | 1973 |
The physical chemistry of hemes and hemopeptides. I. Physiochemical properties and reduction of chlorodeuterohemin in organic solvent.
Topics: Carbon Monoxide; Chlorine; Deuterium; Electron Spin Resonance Spectroscopy; Esters; Heme; Histidine; Imidazoles; Ligands; Magnetic Resonance Spectroscopy; Mathematics; Methanol; Organometallic Compounds; Oxidation-Reduction; Pyridines; Solvents; Spectrophotometry; Spectrophotometry, Infrared; Sulfites | 1973 |
Influence of globin structure on the state of the heme. 3. Changes in heme spectra accompanying allosteric transitions in methemoglobin and their implications for heme-heme interaction.
Topics: Azides; Binding Sites; Carbon Monoxide; Cyanides; Electron Spin Resonance Spectroscopy; Fluorine; Globins; Heme; Humans; Hydrogen-Ion Concentration; Inositol; Macromolecular Substances; Magnetic Resonance Spectroscopy; Methemoglobin; Models, Chemical; Organophosphorus Compounds; Oxygen; Oxyhemoglobins; Protein Conformation; Spectrophotometry; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1974 |
Heme-heme interaction between the cytochromes of the mitochondrial respiratory chain.
Topics: Adenosine Triphosphate; Animals; Azides; Binding Sites; Carbon Monoxide; Columbidae; Cyanides; Cytochromes; Electron Spin Resonance Spectroscopy; Electron Transport; Electron Transport Complex IV; Energy Transfer; Heme; Hydrogen-Ion Concentration; Kinetics; Ligands; Mitochondria; Mitochondria, Muscle; Myocardium; Oxygen Consumption; Protein Binding; Protein Conformation; Spectrophotometry | 1974 |
Heme-heme interaction in cytochrome c oxidase: the cooperativity of the hemes of cytochrome c oxidase as evidenced in the reaction with CO.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Columbidae; Computers; Copper; Cytochrome c Group; Cytochromes; Electron Spin Resonance Spectroscopy; Electron Transport Complex IV; Heme; Hydrogen-Ion Concentration; Kinetics; Light; Mitochondria, Muscle; Myocardium; Photochemistry; Potentiometry; Protein Binding; Protein Conformation; Temperature; Time Factors | 1974 |
Kinetics of carbon monoxide binding and electron transfer by cytochrome c polymers.
Topics: Animals; Binding Sites; Carbon Monoxide; Chromatography, Gel; Cytochrome c Group; Electron Transport; Heme; Horses; Hydrogen-Ion Concentration; Kinetics; Methionine; Methylation; Models, Biological; Myocardium; Photochemistry; Photolysis; Spectrophotometry; Sulfites | 1974 |
Mechanism of aliphatic hydroxylation. Tetralin hydroperoxide as an intermediate in the hydroxylation of tetralin in rat-liver homogenate.
Topics: Animals; Azides; Benzoates; Carbon Monoxide; Catalase; Chloromercuribenzoates; Chromatography, Gas; Cytochromes; Heme; Hemoglobins; Hydrogen-Ion Concentration; Iron; Kinetics; Liver; Male; Mercury; Models, Biological; Models, Chemical; NADP; Naphthalenes; Peroxidases; Peroxides; Rats | 1968 |
Sulphite reductase from bakers' yeast: a haemoflavoprotein.
Topics: Benzoates; Carbon Monoxide; Cell-Free System; Chromatography, Gel; Chromatography, Ion Exchange; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Heme; Kinetics; Light; Methods; NADP; Nitrobenzenes; Oxidoreductases; Plant Proteins; Riboflavin; Saccharomyces; Spectrum Analysis; Sulfites; Sulfur Isotopes | 1969 |
Microsomal heme oxygenase. Characterization of the enzyme.
Topics: Animals; Azides; Benzoates; Bilirubin; Brain; Carbon Monoxide; Cyanides; Depression, Chemical; Detergents; Deuterium; Heme; Hemoglobins; In Vitro Techniques; Kidney; Kinetics; Lipase; Lung; Male; Mercury; Methods; Microsomes; Microsomes, Liver; Myoglobin; NADP; Oxygen Consumption; Oxygenases; Phospholipases; Porphyrins; Rats; Spleen; Time Factors; Trypsin | 1969 |
Purification of ctochrome b5-ike hemoprotein from anaerobically grown yeast.
Topics: Air; Carbon Monoxide; Culture Media; Cytochromes; Heme; Methods; NAD; NADP; Oxidation-Reduction; Pigments, Biological; Plant Proteins; Saccharomyces; Solubility; Spectrum Analysis; Trypsin | 1969 |
Microsomal cytochromes b5 and P450 during induction of aryl hydrocarbon hydroxylase activity in mammalian cell culture.
Topics: Animals; Benz(a)Anthracenes; Carbon Monoxide; Cricetinae; Culture Techniques; Cycloheximide; Cytochromes; Depression, Chemical; Enzyme Activation; Enzyme Induction; Female; Fetus; Heme; Hydrocarbons; Liver; Maternal-Fetal Exchange; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; NADP; Pigments, Biological; Pregnancy; Protein Biosynthesis; Rats; Spectrophotometry; Stimulation, Chemical; Time Factors | 1970 |
Phosphatidylcholine requirement in the enzymatic reduction of hemoprotein P-450 and in fatty acid, hydrocarbon, and drug hydroxylation.
Topics: Alkanes; Animals; Benzphetamine; Carbon Monoxide; Electron Transport; Fatty Acids; Heme; Kinetics; Microsomes, Liver; Morphinans; NADP; Oxidoreductases; Phosphatidylcholines; Rats; Spectrophotometry | 1970 |
Preparation and properties of a solubilized form of cytochrome P-450 from chick embryo liver microsomes.
Topics: Acetamides; Allyl Compounds; Animals; Bacillus subtilis; Carbon Monoxide; Cell Fractionation; Chick Embryo; Cytochromes; Depression, Chemical; Detergents; Etiocholanolone; Female; Flavins; Heme; Ketosteroids; Liver; Methods; Methylcholanthrene; Microsomes, Liver; NAD; NADP; Nitrogen; Oxidoreductases; Peptide Hydrolases; Phenobarbital; Pregnanes; Rats; Solubility; Spectrophotometry; Stimulation, Chemical | 1971 |
Incorporation of radioactive- -aminolevulinic acid into microsomal cytochrome P 450 : selective breakdown of the hemoprotein by allylisopropylacetamide and carbon tetrachloride.
Topics: Acetamides; Allyl Compounds; Amides; Amino Acids; Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochromes; Heme; Kinetics; Levulinic Acids; Male; Microsomes, Liver; NADP; Oxidoreductases; Protein Binding; Proteins; Rats; Spectrophotometry; Tritium | 1972 |
Enzymatic degradation of heme. Oxygenative cleavage requiring cytochrome P-450.
Topics: Animals; Carbon Monoxide; Cytochromes; Heme; Light; Male; Mass Spectrometry; Microsomes; Microsomes, Liver; NADP; Oxidoreductases; Oxygen; Oxygen Isotopes; Oxygenases; Photochemistry; Radiation Effects; Rats; Spleen; Water | 1972 |
Effect of heme and non-heme ligands on subunit dissociation of normal and carboxypeptidase-digested hemoglobin. Gel filtration and flash photolysis studies.
Topics: Carbon Monoxide; Carboxyhemoglobin; Carboxylic Acids; Carboxypeptidases; Chromatography, Gel; Drug Stability; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Ligands; Macromolecular Substances; Oxyhemoglobins; Peptides; Photolysis; Phytic Acid; Protein Binding; Protein Conformation; Structure-Activity Relationship; Temperature; X-Ray Diffraction | 1974 |
Drugs and the liver. I. Effects of glutethimide and phenobarbital on hepatic bilirubin clearance, plasma bilirubin turnover and carbon monoxide production in man.
Topics: Bilirubin; Carbon Monoxide; Carbon Radioisotopes; Chromium Radioisotopes; Female; Gilbert Disease; Glutethimide; Half-Life; Heme; Humans; Liver; Male; Phenobarbital; Time Factors; Tritium | 1974 |
A model compound study of the CO-adduct of cytochrome P-450.
Topics: Air; Argon; Binding Sites; Carbon Monoxide; Computers; Cytochrome P-450 Enzyme System; Dimethyl Sulfoxide; Electric Conductivity; Ethanol; Heme; Hydrogen-Ion Concentration; Kinetics; Ligands; Models, Biological; Protein Binding; Protein Conformation; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1974 |
Effects of 2,4-substituents of deuteroheme upon peroxidase functions. Reactions of peroxidase and myoglobin with oxygen, carbon monoxide and alkylisocyanides.
Topics: Animals; Azides; Binding Sites; Carbon Monoxide; Cyanides; Heme; Hydrogen-Ion Concentration; Kinetics; Muscles; Myoglobin; Oxygen; Peroxidases; Plants; Protein Binding; Structure-Activity Relationship; Temperature; Thermodynamics; Whales | 1974 |
Partial restoration of normal functional properties in carboxypeptidase A-digested hemoglobin.
Topics: Carbon Monoxide; Carboxypeptidases; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Inositol; Kinetics; Methods; Oxygen; Phosphates; Photolysis; Protein Binding; Spectrophotometry; Sulfites | 1972 |
Enhancement of heme catabolism by caloric restriction in man.
Topics: Adult; Bilirubin; Carbon Monoxide; Chromatography, Gas; Fasting; Female; Haptoglobins; Heme; Hemopexin; Humans; Iron; Male; Respiration; Stimulation, Chemical | 1972 |
High resolution proton magnetic resonance study of the two quaternary states in fully ligated hemoglobin Kansas.
Topics: Allosteric Regulation; Binding Sites; Buffers; Carbon Monoxide; Chromatography, Ion Exchange; Deuterium; Dialysis; Diphosphoglyceric Acids; Heme; Hemoglobins; Hemoglobins, Abnormal; Humans; Inositol; Kansas; Macromolecular Substances; Magnetic Resonance Spectroscopy; Male; Osmolar Concentration; Oxygen; Protein Binding; Protons; Structure-Activity Relationship | 1972 |
Functional properties of native and reconstituted hemoglobins from Chironomus thummi thummi.
Topics: Binding Sites; Carbon Monoxide; Cyanides; Deuterium; Diptera; Globins; Heme; Hemoglobins; Hydrogen-Ion Concentration; Kinetics; Oxygen; Protein Binding; Spectrophotometry, Ultraviolet | 1972 |
Observation of the dissociation of unliganded hemoglobin.
Topics: Binding Sites; Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Hemoglobins; Ligands; Macromolecular Substances; Mathematics; Phosphates; Protein Binding; Protein Conformation; Sodium Chloride; Spectrophotometry | 1972 |
Effects of anions and ligands on the tertiary structure around ligand binding site in human adult hemoglobin.
Topics: Adult; Binding Sites; Carbon Monoxide; Deuterium; Diphosphoglyceric Acids; Heme; Hemoglobins; Histidine; Humans; Hydrogen-Ion Concentration; Inositol; Magnetic Resonance Spectroscopy; Oxygen; Phosphates; Potassium Chloride; Protein Binding; Protein Conformation; Sulfates; Tromethamine; Valine | 1973 |
p-Mercuribenzoate as an indicator of conformation change in hemoglobin.
Topics: Carbon Monoxide; Heme; Hemoglobins; Hydrogen-Ion Concentration; Kinetics; Ligands; Macromolecular Substances; Mercuribenzoates; Nitriles; Peptides; Protein Binding; Protein Conformation; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds | 1973 |
The P-450 nature of the carbon monoxide complex of ferrous chloroperoxidase.
Topics: Benzene Derivatives; Carbon Monoxide; Chlorine; Cyanides; Cytochrome P-450 Enzyme System; Cytochromes; Heme; Imidazoles; Iron; Isoelectric Focusing; Mitosporic Fungi; Nitrous Oxide; Oxidation-Reduction; Peroxidases; Protein Denaturation; Spectrophotometry; Spectrophotometry, Ultraviolet | 1973 |
Nonequivalence of the and chains in the reaction of hybrid-heme hemoglobin with carbon monoxide.
Topics: Binding Sites; Carbon Monoxide; Carboxyhemoglobin; Catalysis; Heme; Hemoglobins; Kinetics; Macromolecular Substances; Nitric Oxide; Peptides; Protein Binding; Protein Conformation; Spectrophotometry; Structure-Activity Relationship | 1973 |
Induction of drug metabolism. VII. Differences in P-420 hemoproteins from untreated and 3-methylcholanthrene-treated rats.
Topics: Animals; Biotransformation; Blood Proteins; Carbon Monoxide; Centrifugation, Density Gradient; Cytochromes; Electrophoresis, Disc; Heme; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Pharmaceutical Preparations; Rats; Sucrose; Time Factors; Tritium | 1973 |
Reconstitution of carbon monoxide-binding particles after removal of heme by serum albumin.
Topics: Animals; Blood Proteins; Carbon Isotopes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Heme; Humans; In Vitro Techniques; Male; Microsomes, Liver; Rats; Serum Albumin; Spectrophotometry; Temperature; Time Factors; Tritium | 1973 |
Effects of methylmercury on microsomal mixed-function oxidase components of rodents.
Topics: Animals; Carbon Monoxide; Chlordan; Cytochrome P-450 Enzyme System; Female; Guinea Pigs; Heme; In Vitro Techniques; Levulinic Acids; Male; Mercury; Methylmercury Compounds; Mice; Microsomes, Liver; Organometallic Compounds; Oxidoreductases; Rats; Sex Factors; Species Specificity; Spectrum Analysis; Tritium | 1973 |
Oxidation of deuteroferrihaem by hydrogen peroxide.
Topics: Carbon Monoxide; Deuterium; Heme; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iron; Kinetics; Mass Spectrometry; Models, Chemical; Oxidation-Reduction; Oxygen; Spectrophotometry | 1973 |
Binding of carbon monoxide by deuteroheme in organic solvents. Evidence for the formation of dicarbonyldeuteroheme in non-coordinating solvents.
Topics: Benzene; Carbon Monoxide; Chemical Phenomena; Chemistry; Deuterium; Heme; Ketones; Ligands; Solvents; Spectrophotometry | 1973 |
Pink teeth appearing as a post-mortem phenomenon.
Topics: Adult; Animals; Carbon Monoxide; Dogs; Female; Forensic Medicine; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Isoelectric Focusing; Male; Postmortem Changes; Spectrophotometry; Tooth; Tooth Discoloration | 1973 |
Proximal base influence on the binding of oxygen and carbon monoxide to heme.
Topics: Animals; Binding, Competitive; Carbon Monoxide; Cetacea; Heme; Imidazoles; Ligands; Molecular Conformation; Myoglobin; Oxygen; Protein Binding; Pyridines | 1973 |
Purification and molecular properties of yeast hemoglobin.
Topics: Amino Acids; Animals; Binding Sites; Candida; Carbon Monoxide; Cetacea; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Thin Layer; Electrophoresis, Polyacrylamide Gel; Flavin-Adenine Dinucleotide; Heme; Hemoglobins; Humans; Iron; Kinetics; Molecular Weight; Myoglobin; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Atomic | 1973 |
Characterization of the heme of cytochrome P-450 using gas chromatography-mass spectrometry.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Cytochrome P-450 Enzyme System; Heme; Hemoglobins; Humans; Male; Mass Spectrometry; Membranes; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Porphyrins; Rabbits; Rats; Solubility | 1973 |
Comparison of plasma bilirubin turnover and carbon monoxide production in man.
Topics: Bilirubin; Carbon Monoxide; Carbon Radioisotopes; Erythrocyte Aging; Female; Heme; Hemolysis; Humans; Hyperbilirubinemia, Hereditary; Male; Regression Analysis; Tritium | 1974 |
Cyclic variation of rate of carbon monoxide production in normal women.
Topics: Adolescent; Adult; Carbon Monoxide; Female; Heme; Humans; Liver; Male; Menstruation; Periodicity; Progesterone; Sex Factors | 1974 |
Activity of various metalloporphyrin protein complexes with microsomal heme oxygenase.
Topics: Animals; Carbon Monoxide; Cobalt; Copper; Cyanides; Deuterium; Fluorides; Globins; Heme; Hemeproteins; Iron; Ligands; Male; Metalloproteins; Methemoglobin; Microsomes; Microsomes, Liver; Nickel; Oxygenases; Palladium; Porphyrins; Potassium; Rats; Spleen; Structure-Activity Relationship | 1974 |
Kinetics and equilibria for carbon monoxide binding to ferrous phthalocyanine complexes.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Indoles; Iron; Kinetics; Models, Chemical; Organometallic Compounds; Protein Binding | 1974 |
Appearance of (14C)O in expired air and incorporation of 14C in hemoglobin after administration of glycine-2-(14C) in man.
Topics: Adult; Carbon Dioxide; Carbon Monoxide; Carbon Radioisotopes; Cell Survival; Erythrocytes; Glycine; Heme; Hemoglobins; Humans; Male; Middle Aged; Respiration; Time Factors | 1974 |
Cytochrome b-561 as the single heme protein of the bovine adrenal chromaffin granule membrane.
Topics: Adrenal Medulla; Animals; Binding Sites; Carbon Monoxide; Cattle; Cell Membrane; Cytochromes; Heme; Oxidation-Reduction; Protein Binding; Protein Denaturation; Spectrophotometry; Sulfites; Ultracentrifugation | 1974 |
Effect of several endogenous substances--including porphyrins, hematin, and carbon monoxide--on hepatic clearance of sulfobromophthalein.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Biotransformation; Carbon Monoxide; Heme; Levulinic Acids; Liver; Liver Function Tests; Male; Mice; Porphyrins; Sulfobromophthalein; Time Factors | 1974 |
Effects of ligands and organic phosphates on functional properties of human adult hemoglobin.
Topics: Adult; Carbon Monoxide; Computers; Deuterium; Diphosphoglyceric Acids; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Inositol; Ligands; Magnetic Resonance Spectroscopy; Mathematics; Organophosphorus Compounds; Oxygen Consumption; Protein Binding; Protons; Structure-Activity Relationship | 1974 |
Heme-linked properties of Euglena cytochrome f.
Topics: Alkylation; Carbon Monoxide; Cyanides; Cytochromes; Euglena; Heme; Hydrogen-Ion Concentration; Iron; Kinetics; Metalloproteins; Methionine; Molecular Conformation; Osmolar Concentration; Oxidation-Reduction; Spectrophotometry; Temperature; Thermodynamics | 1974 |
Studies on heme transfer from microsomal hemoproteins to heme-binding plasma proteins.
Topics: Animals; Apoproteins; Biological Transport; Blood Proteins; Carbon Monoxide; Chromatography, DEAE-Cellulose; Cytochrome P-450 Enzyme System; Cytochromes; Heme; Hemeproteins; Hemopexin; In Vitro Techniques; Levulinic Acids; Male; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Protein Binding; Rats; Serum Albumin; Spectrophotometry, Ultraviolet; Tritium | 1974 |
Cytochrome P-450cam. III. Removal and replacement of ferriprotoporphyrin IX.
Topics: Animals; Apoproteins; Benzoates; Carbon Monoxide; Cattle; Chloromercuribenzoates; Chromatography, Thin Layer; Cold Temperature; Cysteine; Cytochrome P-450 Enzyme System; Drug Stability; Glycerol; Heme; Hydrogen-Ion Concentration; Iron; Kinetics; Nitro Compounds; Oxidation-Reduction; Porphyrins; Pseudomonas; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfhydryl Compounds; Time Factors | 1974 |
The formation of biliverdin by chicken macrophages in tissue culture. Observations on the effect of inhibitors.
Topics: Acetanilides; Animals; Ascorbic Acid; Azides; Bile Pigments; Carbon Monoxide; Chickens; Chloramphenicol; Culture Techniques; Cyanides; Cycloheximide; Dactinomycin; Erythrocytes; Ethylmaleimide; Female; Heme; Hydrogen Peroxide; Macrophages; Metabolism; Microscopy, Phase-Contrast; Mitomycins; Phagocytosis; Phenobarbital; Proadifen; Quinacrine; Spectrophotometry; Spectrum Analysis; Stimulation, Chemical; Triazoles | 1970 |
Pseudomonas denitrificans cytochrome cc'.
Topics: Amino Acid Sequence; Amino Acids; Carbon Monoxide; Chemical Phenomena; Chemistry; Cytochromes; Endopeptidases; Heme; Hemoglobins; Hydrogen-Ion Concentration; Molecular Weight; Myoglobin; Oxidation-Reduction; Papain; Pepsin A; Pseudomonas; Spectrophotometry; Trypsin; Ultracentrifugation | 1970 |
Early studies of CO production.
Topics: Anemia, Hemolytic; Animals; Blood Volume; Carbon Monoxide; Dogs; Female; Guinea Pigs; Heme; Hemoglobinometry; Hemolysis; History, 19th Century; History, 20th Century; Horses; Humans; In Vitro Techniques; Methods; Nephritis; Physiology; Pregnancy; Pulmonary Alveoli; Rabbits; Respiration; Sweden; Thrombophlebitis | 1970 |
Electron transport systems of Rhizobium japonicum. I. Haemoprotein P-450, other CO-reactive pigments, cytochromes and oxidases in bacteroids from N2-fixing root nodules.
Topics: Bacterial Proteins; Carbon Monoxide; Cyanides; Cytochromes; Edetic Acid; Electron Transport; Glycine max; Heme; Nitrogen Fixation; Oxidoreductases; Oxygen Consumption; Pigments, Biological; Rhizobium; Spectrum Analysis; Succinates | 1969 |
Dissociation of hemoglobin into subunits. Monomer formation and the influence of ligands.
Topics: Azides; Carbon Monoxide; Cyanides; Edetic Acid; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Male; Methemoglobin; Molecular Weight; Polymers; Spectrophotometry; Thiocyanates; Ultracentrifugation | 1971 |
Variation in the rate of endogenous carbon monoxide production in normal human beings.
Topics: Adult; Bilirubin; Carbon Monoxide; Female; Hematocrit; Heme; Hemoglobins; Humans; Iron; Male; Menstruation; Methods; Middle Aged; Protein Binding; Respiration; Sex Factors; Spirometry; Time Factors | 1972 |
Heme-modification studies on horseradish peroxidase.
Topics: Apoproteins; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Deuterium; Esters; Fluorides; Guaiacol; Heme; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Peroxidases; Peroxides; Plants; Porphyrins; Spectrophotometry; Structure-Activity Relationship; Thiosulfates; Ultraviolet Rays | 1972 |
The functional properties of hemoglobin Bethesda ( 2 2 145His ).
Topics: Amino Acids; Binding Sites; Buffers; Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Hemoglobins, Abnormal; Histidine; Humans; Hydrogen-Ion Concentration; Inositol; Kinetics; Macromolecular Substances; Mutation; Nitriles; Osmolar Concentration; Oxygen; Peptides; Protein Binding; Protein Conformation; Spectrophotometry; Tyrosine; Ultracentrifugation | 1972 |
Hemoglobin: resonance Raman spectra.
Topics: Azides; Carbon Monoxide; Heme; Hemoglobins; Humans; Iron; Light; Methemoglobin; Oxygen; Scattering, Radiation; Spectrum Analysis | 1972 |
Quantitative recovery of 14 C-labeled carbon monoxide ( 14 CO) from viable heme-labeled red blood cells in the rat.
Topics: Animals; Blood Transfusion; Carbon Isotopes; Carbon Monoxide; Cell Survival; Erythrocyte Aging; Erythrocytes; Glycine; Heme; Hemolysis; Rats; Rats, Inbred Strains | 1972 |
Equilibria and kinetics of ligand binding by leghemoglobin from soybean root nodules.
Topics: Carbon Monoxide; Chromatography, Gel; Glycine max; Heme; Hydrogen-Ion Concentration; Kinetics; Mathematics; Nitric Oxide; Osmolar Concentration; Oxidation-Reduction; Oxygen; Partial Pressure; Photolysis; Plant Proteins; Protein Binding; Spectrophotometry; Sulfites; Thermodynamics; Ultracentrifugation | 1972 |
Circular dichroism studies of the perturbations of cytochrome c by alcohols.
Topics: 1-Propanol; Alcohols; Animals; Carbon Monoxide; Circular Dichroism; Cytochromes; Ethanol; Ferricyanides; Heme; Horses; Methanol; Myocardium; Oxidation-Reduction; Protein Conformation; Sulfites | 1972 |
Kinetics of conformation change of sperm-whale myoglobin. 3. Folding and unfolding of apomyoglobin and the suggested overall mechanism.
Topics: Aniline Compounds; Animals; Carbon Monoxide; Cetacea; Globins; Heme; Hydrogen-Ion Concentration; Kinetics; Macromolecular Substances; Mathematics; Myoglobin; Naphthalenes; Optical Rotation; Protein Conformation; Spectrometry, Fluorescence; Sulfonic Acids | 1972 |
Nuclear magnetic resonance studies of hemoglobins. VII. Tertiary structure around ligand binding site in carbonmonoxyhemoglobin.
Topics: Animals; Australia; Carbon Monoxide; Chloromercuribenzoates; Cytochromes; Deuterium; Fetal Hemoglobin; Heme; Hemoglobins; Hemoglobins, Abnormal; Horses; Humans; Macromolecular Substances; Magnetic Resonance Spectroscopy; Myocardium; Protein Conformation; Switzerland; Umbilical Cord; Valine | 1972 |
[Dissociation kinetics of complexes between alkyliso-cyanides and monomeric or oligomeric hemoglobins].
Topics: Allosteric Regulation; Animals; Binding Sites; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyprinidae; Diptera; Fetal Hemoglobin; Heme; Hemoglobins; Horses; Humans; Inositol; Kinetics; Macromolecular Substances; Myoglobin; Nitriles; Species Specificity | 1972 |
Preliminary characterization of a variant co-binding heme protein from Nitrosomonas.
Topics: Ammonium Sulfate; Bacterial Proteins; Bile Acids and Salts; Carbon Monoxide; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Cyanides; Ethanol; Heme; Hydrazines; Hydrogen-Ion Concentration; Hydroxylamines; Molecular Weight; Nitrosomonas; Oxidation-Reduction; Pronase; Ribonucleases; Spectrophotometry; Sulfites; Time Factors | 1972 |
Ligand binding in hemoglobin J Capetown.
Topics: Binding Sites; Carbon Monoxide; Glutamine; Haptoglobins; Heme; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Kinetics; Leucine; Molecular Biology; Oxygen; Sulfur | 1971 |
Effect of intravenous urea in invert sugar on heme catabolism in sickle-cell anemia.
Topics: Anemia, Sickle Cell; Bilirubin; Blood Urea Nitrogen; Carbon Monoxide; Erythrocyte Count; Female; Fructose; Glucose; Hematocrit; Heme; Hemoglobins; Humans; Injections, Intravenous; Male; Reticulocytes; Solutions; Urea | 1971 |
[Binding of carbon tetrachloride to reduced microsomal cytochrome P-450 and to heme].
Topics: Animals; Binding Sites; Carbon Monoxide; Carbon Tetrachloride; Carbon Tetrachloride Poisoning; Cytochromes; Heme; Hexobarbital; Iron; Male; Microsomes, Liver; Oxidation-Reduction; Oxygen; Protein Binding; Rabbits; Spectrophotometry | 1971 |
Limited proteolysis of horse heart cytochrome c.
Topics: Amino Acids; Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Cytochromes; Heart; Heme; Horses; Molecular Weight; Oxidation-Reduction; Peptide Hydrolases; Protein Binding; Spectrum Analysis | 1971 |
The reaction of n-butyl isocyanide with human hemoglobin. I. Determination of the kinetic parameters involved in the last step in ligand binding.
Topics: Animals; Carbon Monoxide; Cetacea; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Glycerophosphates; Haptoglobins; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Inositol; Kinetics; Macromolecular Substances; Mathematics; Mercaptoethanol; Myoglobin; Nitriles; Nitrogen Oxides; Oxygen; Peptides; Phosphates; Photolysis; Protein Binding; Spectrophotometry | 1971 |
Studies on the catalytic and allosteric sites in modulating the reactivity of tryptophan oxygenase with heme ligands. II. Carbon monoxide derivatives.
Topics: Allosteric Regulation; Binding Sites; Carbon Monoxide; Catalysis; Chemical Phenomena; Chemistry; Fluorine; Heme; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Oxidation-Reduction; Protein Binding; Protein Conformation; Pseudomonas; Spectrophotometry; Sulfites; Tryptophan; Tryptophan Oxygenase | 1971 |
Purification and properties of cytochrome c 3 of Desulfovibrio vulgaris, Miyazaki.
Topics: Amino Acids; Carbon Monoxide; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Chromatography, Thin Layer; Cytochromes; Dansyl Compounds; Desulfovibrio; Electron Transport; Heme; Histidine; Hydrogen; Iron; Kinetics; Mathematics; Molecular Weight; Oxidation-Reduction; Oxidoreductases; Potentiometry; Species Specificity; Spectrophotometry; Spectrum Analysis; Sulfites; Ultraviolet Rays | 1971 |
Properties of erythrocruorin from Cirraformia grandis.
Topics: Amino Acids; Ammonium Sulfate; Animals; Annelida; Carbon Monoxide; Chemical Precipitation; Chromatography, Gel; Chromatography, Ion Exchange; Circular Dichroism; Detergents; Electrophoresis; Electrophoresis, Disc; Heme; Hydrogen-Ion Concentration; Macromolecular Substances; Mathematics; Molecular Weight; Oxygen; Pigments, Biological; Protein Binding; Proteins; Spectrophotometry; Sulfuric Acids; Ultracentrifugation | 1971 |
Chromatography of radioactive microsomal hemoproteins on diethylaminoethyl cellulose.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Chromatography, DEAE-Cellulose; Cytochromes; Heme; Kinetics; Levulinic Acids; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Proteins; Rats; Rats, Inbred Strains; Solubility; Time Factors; Tritium | 1971 |
The formation of biliverdin from haemin suspensions by chicken macrophages in culture.
Topics: Animals; Azides; Bile Pigments; Carbon Isotopes; Carbon Monoxide; Chemical Phenomena; Chemistry; Chickens; Culture Techniques; Cyanides; Cytochromes; Cytoplasm; Erythrocytes; Ethylmaleimide; Heme; Hemoglobins; Macrophages; Microsomes; Mitochondria; Models, Biological; Oxidation-Reduction | 1971 |
Effects of inducers of liver microsomal enzymes on the composition of microsomal hemoprotein.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Chlordan; Cytochromes; Enzyme Induction; Heme; Hemeproteins; Hydroxylation; In Vitro Techniques; Levulinic Acids; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Time Factors; Tritium | 1971 |
The binding of carbon dioxide by horse haemoglobin.
Topics: Amino Acids; Animals; Autoradiography; Carbon Dioxide; Carbon Isotopes; Carbon Monoxide; Chromatography; Cyanates; Heme; Hemoglobins; Horses; Hydrogen-Ion Concentration; Peptides; Protein Binding; Sulfur Isotopes | 1971 |
Aryl hydrocarbon hydroxylase induction in cell culture as a function of gene expression.
Topics: Aging; Animals; Animals, Newborn; Benz(a)Anthracenes; Benzopyrenes; Carbon Monoxide; Cell Line; Cricetinae; Cycloheximide; Cytochromes; Dactinomycin; Enzyme Induction; Female; Fetus; Fluorometry; Gestational Age; Half-Life; Heme; Kinetics; Liver; Mice; Microsomes, Liver; Mixed Function Oxygenases; Models, Biological; Molecular Biology; Pregnancy; Spectrophotometry; Tritium | 1971 |
Alterations in the heme-carbon monoxide bond strength.
Topics: Argon; Binding Sites; Carbon Monoxide; Chemical Phenomena; Chemistry; Crystallins; Cyclopropanes; Heme; Histidine; Krypton; Lasers; Methods; Myoglobin; Nitrogen; Photolysis; Xenon | 1970 |
Carbon monoxide production and heme catabolism.
Topics: Acetamides; Allyl Compounds; Anemia, Sideroblastic; Animals; Bile Pigments; Bone Marrow; Carbon Isotopes; Carbon Monoxide; Dogs; Erythrocytes; Erythropoiesis; Glycine; Heme; Hemoglobins; Humans; Levulinic Acids; Liver; Mononuclear Phagocyte System; Phenobarbital; Porphyrias; Reticulocytes; Time Factors | 1970 |
Kinetic aspects of endogenous carbon monoxide production in experimental animals.
Topics: Acetamides; Allyl Compounds; Anemia, Hypochromic; Animals; Birds; Blood Transfusion; Carbon Isotopes; Carbon Monoxide; Cell Survival; Erythrocyte Aging; Erythropoiesis; Female; Glycine; Hematocrit; Heme; Hemoglobins; Hemolysis; Iron Isotopes; Kinetics; Male; Methods; Mice; Phenobarbital; Phenylhydrazines; Rats; Reticulocytes; Time Factors; Veins | 1970 |
The hemophagous organ of the placenta and in vitro studies of endogenous carbon monoxide production.
Topics: Animals; Bile Pigments; Carbon Isotopes; Carbon Monoxide; Cell-Free System; Chromatography, Thin Layer; Dogs; Female; Heme; Hemoglobins; In Vitro Techniques; Mitochondria; Oxidation-Reduction; Placenta; Pregnancy; Serum Globulins; Spectrophotometry | 1970 |
The combination of carbon monoxide-haem with apoperoxidase.
Topics: Binding Sites; Carbon Monoxide; Heme; Kinetics; Light; Models, Chemical; Myoglobin; Peroxidases; Plants | 1969 |
Relation between allosteric effects and changes in the energy of bonding between molecular subunits.
Topics: Binding Sites; Carbon Monoxide; Chemical Phenomena; Chemistry, Physical; Heme; Hemoglobins; Hydrogen-Ion Concentration; Oxygen; Proteins; Thermodynamics | 1969 |
Circular dichroism and absorption spectra of horse radish peroxidase and sperm whale myoglobin in the Soret region.
Topics: Animals; Binding Sites; Carbon Monoxide; Cetacea; Chemical Phenomena; Chemistry; Cyanides; Heme; Iron; Myoglobin; Oxidation-Reduction; Peroxidases; Plants; Spectrophotometry; Spectrum Analysis | 1969 |
Rates of reaction with ligands of haemoproteins reconstituted with unnatural haems.
Topics: Animals; Binding Sites; Carbon Monoxide; Cetacea; Cyanides; Heme; Kinetics; Mollusca; Myoglobin; Peroxidases; Plants | 1969 |
Autocatalytic peroxidation of ferrocytochrome c.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cytochromes; Heme; Horses; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iron; Kinetics; Mathematics; Myocardium; Oxidation-Reduction; Peroxidases; Spectrophotometry; Sulfites; Time Factors | 1969 |
The membrane-bound carbon monoxide-reactive hemoproteins in the extreme halophiles.
Topics: Ascorbic Acid; Bacterial Proteins; Carbon Monoxide; Cell Membrane; Cytochromes; Halobacterium; Heme; Methods; Species Specificity; Spectrophotometry; Time Factors | 1970 |
Infrared studies of azido, cyano, and other derivatives of metmyoglobin, methemoglobin, and hemins.
Topics: Azides; Carbon Monoxide; Cyanates; Cyanides; Deuterium; Heme; Hemoglobins; Histidine; Hydrogen; Hydrogen-Ion Concentration; Infrared Rays; Myoglobin; Potassium; Sodium; Spectrophotometry; Thiocyanates | 1970 |
Acid denaturation of carbonylhemoglobin. Protein unfolding without heme detachment.
Topics: Animals; Binding Sites; Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Hemoglobins; Horses; Humans; Hydrogen-Ion Concentration; Kinetics; Optical Rotatory Dispersion; Protein Denaturation; Tryptophan; Ultraviolet Rays | 1970 |
Enhancement by phenobarbital and diphenylhydantoin of carbon monoxide production in normal man.
Topics: Adult; Bilirubin; Carbon Monoxide; Heme; Humans; Liver; Male; Phenobarbital; Phenytoin | 1970 |
Catabolism of heme in vivo: comparison of the simultaneous production of bilirubin and carbon monoxide.
Topics: Animals; Bile; Bilirubin; Carbon Isotopes; Carbon Monoxide; Feces; Glycine; Heme; Injections, Intravenous; Liver; Phenobarbital; Rats; Respiration; Urea | 1970 |
Optical rotatory dispersion of Chromatium cytochrome c552.
Topics: Carbon Monoxide; Chromatium; Computers; Cytochromes; Flavins; Heme; Methods; Optical Rotatory Dispersion; Oxidation-Reduction; Spectrum Analysis; Ultraviolet Rays | 1970 |
Redox-dependent conformational changes of rabbit liver cytochrome P-450.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cytochromes; Endoplasmic Reticulum; Heme; Liver; Microsomes, Liver; Optical Rotatory Dispersion; Oxidation-Reduction; Phenobarbital; Pigments, Biological; Rabbits; Spectrophotometry; Ultraviolet Rays | 1970 |
Heme-heme interaction of crystalline lamprey hemoglobin. Kinetics and equilibrium of the reaction of carbon monoxide.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Crystallization; Eels; Heme; Hemoglobins; Kinetics; Postural Balance; Spectrophotometry | 1970 |
Distribution of radioactive hemoprotein and CO-binding pigment in rough and smooth endoplasmic reticulum of rat liver.
Topics: Amino Acids; Animals; Carbon Monoxide; Cytochromes; Endoplasmic Reticulum; Heme; Kinetics; Leucine; Levulinic Acids; Liver; Male; Microsomes, Liver; Pigments, Biological; Protein Biosynthesis; Rats; Tritium | 1970 |
Endogenous production of 14CO: A method for calculation of RBC life-span in vivo.
Topics: Anemia; Anemia, Hypochromic; Animals; Carbon Isotopes; Carbon Monoxide; Erythrocyte Aging; Erythrocytes; Female; Gastrectomy; Glycine; Heme; Hemoglobins; Hemolysis; Hypophysectomy; Male; Mice; Phenylhydrazines; Rats; Splenectomy | 1970 |
The role of hemoglobin heme loss in Heinz body formation: studies with a partially heme-deficient hemoglobin and with genetically unstable hemoglobins.
Topics: Anemia, Hemolytic, Congenital; Binding Sites; Blood Protein Electrophoresis; Carbon Monoxide; Cyanides; Glutathione; Heinz Bodies; Heme; Hemoglobins, Abnormal; Histidine; Hot Temperature; Humans; Methods; Peptides; Protein Binding; Sulfhydryl Compounds | 1970 |
The effect of pH on the reactions of oxygen and carbon monoxide with the hemoglobin of the carp, Cyprinus carpio.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyprinidae; Heme; Hemoglobins; Hydrogen-Ion Concentration; Kinetics; Oxygen | 1970 |
Quantitation of red blood cell destruction associated with valvular disease and prosthetic valves.
Topics: Aortic Valve; Aortic Valve Insufficiency; Aortic Valve Stenosis; Carbon Monoxide; Female; Heart Valve Diseases; Heart Valve Prosthesis; Heme; Hemoglobins; Hemolysis; Humans; Male; Methods; Mitral Valve; Mitral Valve Insufficiency; Mitral Valve Stenosis; Plasma | 1970 |
Substituted iron-chlorins and their complexes with globin. Spectral comparisons with myeloperoxidase.
Topics: Blood Proteins; Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Deuterium; Fluorides; Globins; Heme; Hemoglobins; Hydrogen-Ion Concentration; Iron; Peptides; Peroxidases; Porphyrins; Pyridines; Spectrophotometry | 1970 |
Some features of the reaction between cobaltinitrite and hemoglobin.
Topics: Carbon Monoxide; Chlorides; Cobalt; Ferricyanides; Heme; Hemoglobins; Humans; Indicators and Reagents; Iron; Methemoglobin; Nitrites; Oxidation-Reduction; Oxygen; Oxygen Consumption; Pigments, Biological; Polarography; Potassium; Protein Binding; Sodium; Spectrum Analysis; Time Factors | 1970 |
Kinetics of the reaction of hybrid-heme hemoglobins with carbon monoxide.
Topics: Binding Sites; Carbon Monoxide; Chemical Phenomena; Chemistry; Deuterium; Heme; Hemoglobins; Histidine; Iron; Methemoglobin | 1970 |
The hemoprotein content of Chromatium sp. strain D.
Topics: Ascorbic Acid; Carbon Monoxide; Chromatium; Cytochromes; Ferricyanides; Heme; Oxidation-Reduction; Solvents; Spectrophotometry; Sulfites | 1970 |
Reaction of human CO hemoglobin with p,p'-difluoro-m,m'-dinitrodiphenylsulfone.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Chromatography, Gel; Chromatography, Ion Exchange; Heme; Hemoglobins; Humans; Hydrocarbons, Halogenated; Infrared Rays; Nitrobenzenes; Oxygen; Spectrophotometry; Sulfones; Valine | 1970 |
Splenic destruction of newly-formed red blood cells and shortened erythrocyte survival in mice with congenital microcytosis.
Topics: Anemia, Hemolytic, Congenital; Animals; Carbon Isotopes; Carbon Monoxide; Erythrocytes; Erythropoiesis; Female; Glycine; Heme; Hemoglobins; Hemolysis; Homozygote; Male; Mice; Microscopy, Electron, Scanning; Reticulocytes; Spleen; Splenectomy | 1970 |
Purification and properties of an erythrocyte hemoprotein with a unique prosthetic group.
Topics: Blood Proteins; Carbon Monoxide; Chromatography, DEAE-Cellulose; Chromatography, Gel; Chromatography, Ion Exchange; Cyanides; Electrophoresis, Disc; Erythrocytes; Heme; Humans; Molecular Weight; Oxidation-Reduction; Pyridines; Spectrophotometry; Ultracentrifugation | 1970 |
The effect of p-hydroxymercuribenzoate on the reactions of the isolated gamma chains of human hemoglobin with ligands.
Topics: Benzoates; Carbon Monoxide; Chemical Phenomena; Chemistry; Fetal Hemoglobin; Heme; Humans; Kinetics; Mercury; Organometallic Compounds; Oxygen; Peptides; Sulfhydryl Compounds | 1971 |
Endogenous carbon monoxide production measured by gas-phase analysis: an estimation of heme catabolic rate.
Topics: Anemia, Hemolytic; Carbon Monoxide; Erythrocyte Aging; Erythrocytes; Heme; Hemoglobins; Humans; Methods | 1971 |
Conformational studies on human and rabbit plasma hemopexin and on the effect of ligands on the rabbit heme-hemopexin complex.
Topics: Animals; Blood Proteins; Carbon Monoxide; Chemical Phenomena; Chemistry; Circular Dichroism; Cyanides; Formates; Glycoproteins; Heme; Humans; Hydrogen-Ion Concentration; Optical Rotatory Dispersion; Osmolar Concentration; Oxidation-Reduction; Oxygen; Potassium; Protein Binding; Rabbits; Species Specificity; Sulfites; Ultraviolet Rays; Urea | 1971 |
Structure and function of human semihemoglobins alpha and beta.
Topics: Carbon Monoxide; Circular Dichroism; Heme; Hemoglobins; Humans; Kinetics; Oxygen; Protein Binding; Spectrophotometry; Spectrum Analysis; Ultracentrifugation | 1971 |
The use of disc gel electrophoresis with nonionic detergent in the purification of cytochrome f from spinach grana membranes.
Topics: Acrylates; Carbon Monoxide; Chloroplasts; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cold Temperature; Cytochromes; Detergents; Electrophoresis, Disc; Gels; Guanidines; Heme; Iron; Membranes; Methods; Molecular Weight; Oxidation-Reduction; Plant Cells; Solubility; Spectrophotometry; Sulfuric Acids; Surface-Active Agents; Ultracentrifugation; Urea | 1971 |
Kinetics of association of carbon monoxide with haemoglobin at low temperature.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Hemoglobins; Humans; Kinetics; Light; Protein Binding; Temperature | 1968 |
The proton-binding behavior of human hemoglobin and its subunits in their native state.
Topics: Acids; Amines; Benzoates; Binding Sites; Carbon Monoxide; Heme; Hemoglobins; Histidine; Humans; Hydrogen-Ion Concentration; Iron; Lysine; Mercury; Peptides; Protons; Spectrophotometry; Sulfhydryl Compounds; Tyrosine; Water | 1968 |
Studies on the interaction of carbon monoxide with tryptophan oxygenase of Pseudomonas.
Topics: Ascorbic Acid; Binding Sites; Carbon Monoxide; Heme; Iron; Kinetics; Light; Oxygen; Porphyrins; Protein Binding; Pseudomonas; Tryptophan; Tryptophan Oxygenase | 1968 |
Methyl viologen-linked sulfite reductase from spinach leaves: a hemoprotein.
Topics: Carbon Monoxide; Catalysis; Chlorides; Heme; Indicators and Reagents; Light; Oxidation-Reduction; Oxidoreductases; Plant Proteins; Plants, Edible; Pyridines; Quaternary Ammonium Compounds; Spectrophotometry | 1968 |
The electronic structure of protoheme proteins. I. An electron paramagnetic resonance and optical study of horseradish peroxidase and its derivatives.
Topics: Animals; Carbon Monoxide; Cetacea; Chemical Phenomena; Chemistry, Physical; Cold Temperature; Cyanides; Electrons; Heme; Hemoglobins; Hydrogen-Ion Concentration; Iron; Magnoliopsida; Myoglobin; Oxygen; Peroxidases; Spectrum Analysis | 1968 |
Functional properties of a hemoglobin carrying heme only on alpha chains.
Topics: Binding Sites; Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Kinetics; Light; Oxygen; Peptides; Spectrophotometry | 1968 |
Models for haem-haem interaction.
Topics: Azides; Carbon Monoxide; Chemical Phenomena; Chemistry, Physical; Fluorides; Heme; Hemoglobins; Methemoglobin; Models, Chemical; Oxygen | 1968 |
Crystal forms of lamprey hemoglobin and crystalline transitions between ligand states.
Topics: Animals; Carbon Monoxide; Crystallization; Crystallography; Fishes; Heme; Hemoglobins; Iron; Spectrophotometry; X-Ray Diffraction | 1968 |
Spectral interactions of protoheme with ethyl isocyanide and some other ligands in enutral pH region.
Topics: Alcohols; Bile Acids and Salts; Carbon Monoxide; Chemical Phenomena; Chemistry, Physical; Color; Cyanides; Heme; Hydrogen-Ion Concentration; Imidazoles; Phenols; Phosphates; Pyridines; Spectrophotometry | 1968 |
An infrared study of bound carbon monoxide in the human red blood cell, isolated hemoglobin, and heme carbonyls.
Topics: Carbon Isotopes; Carbon Monoxide; Chemical Phenomena; Chemistry; Deuterium; Erythrocytes; Heme; Hemoglobins; Humans; Infrared Rays; Iron; Oxygen Isotopes; Porphyrins; Pyridines; Solvents; Spectrum Analysis | 1968 |
The carbon monoxide-reactive haemoproteins of yeast.
Topics: Candida; Carbon Monoxide; Cell-Free System; Chemical Precipitation; Culture Media; Cyanides; Cytochromes; Glucose; Heme; Hemoglobins; Methods; Oxidation-Reduction; Oxygen; Plant Proteins; Saccharomyces; Spectrophotometry; Spectrum Analysis; Time Factors | 1969 |
Circular dichroism of isolated and recombined hemoglobin chains.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Cyanides; Drug Stability; Heme; Hemoglobins; Humans; Methemoglobin; Oxygen; Peptides; Spectrophotometry; Spectrum Analysis | 1969 |
Change in P-450 content accompanying aerobic formation of mitochondria in yeast.
Topics: Antimycin A; Carbon Monoxide; Chloramphenicol; Cytochromes; Glucose; Heme; Mitochondria; Oxygen; Oxygen Consumption; Pigments, Biological; Proteins; Saccharomyces | 1969 |
Endogenous production of carbon monoxide: the human body as a cause of air pollution.
Topics: Air Pollution; Carbon Monoxide; Carbon Monoxide Poisoning; Heme; Humans | 1969 |
Biphasic decrease of radioactive hemoprotein from liver microsomal CO-binding particles. Effect of 3-methylcholanthrene.
Topics: Amino Acids; Animals; Carbon Monoxide; Cytochromes; Depression, Chemical; Heme; Levulinic Acids; Liver; Male; Methods; Methylcholanthrene; Microsomes; Protein Binding; Protein Biosynthesis; Rats; Solubility; Spectrum Analysis; Time Factors; Tritium | 1969 |
On the rate of a conformation change associated with ligand binding in hemoglobin.
Topics: Benzoates; Carbon Monoxide; Ethylmaleimide; Heme; Hemoglobins; Humans; Iodoacetates; Kinetics; Mercury; Oxygen; Protein Binding; Spectrophotometry; Sulfhydryl Compounds; Time Factors | 1969 |
Iron-chelating enzyme from rat liver.
Topics: Animals; Bile Acids and Salts; Carbon Monoxide; Heme; In Vitro Techniques; Iron Isotopes; Liver; Lyases; Mitochondria; Porphyrins; Rats | 1965 |
Mössbauer effect in hemoglobin and some iron-containing biological compounds.
Topics: Carbon Dioxide; Carbon Monoxide; Cobalt Isotopes; Erythrocytes; Heme; Hemoglobins; Humans; In Vitro Techniques; Iron Isotopes; Nitrogen; Oxygen; Spectrum Analysis | 1965 |
The two forms of the imidazole hemochrome of heme a. A new model for cytochrome.
Topics: Borates; Carbon Monoxide; Chemical Phenomena; Chemistry; Cytochromes; Heme; Imidazoles; Models, Theoretical; Surface-Active Agents | 1966 |
Endogenous production of carbon-14 labeled carbon monoxide: an in vivo technique for the study of heme catabolism.
Topics: Amino Alcohols; Animals; Carbon Isotopes; Carbon Monoxide; Glycine; Heme; Male; Radiometry; Rats; Respiration | 1966 |
The production of carbon monoxide from hemoglobin in vivo.
Topics: Animals; Bile; Carbon Isotopes; Carbon Monoxide; Dogs; Erythrocytes; Ethylmaleimide; Heme; Hemoglobins; Liver; Methemoglobin; Porphyrins | 1967 |
Hematology. I. Quantitative studies of iron and heme metabolism using radioisotope kinetics.
Topics: Carbon Isotopes; Carbon Monoxide; Deficiency Diseases; Glycine; Heme; Humans; Iron; Iron Isotopes; Kinetics; Models, Theoretical | 1967 |
The structure of a hemoglobin carrying only two hemes.
Topics: Binding Sites; Blood Protein Electrophoresis; Carbon Monoxide; Centrifugation, Zonal; Chromatography; Chromatography, Gel; Cyanides; Globins; Heme; Hemoglobins; Hydrogen-Ion Concentration; Iron Isotopes; Methemoglobin; Methylcellulose; Molecular Weight; Peptides; Protein Binding; Spectrophotometry | 1967 |
Cytochrome synthesis and its regulation in Spirillum itersonii.
Topics: Bacterial Proteins; Carbon Monoxide; Chloramphenicol; Culture Media; Cytochromes; Electron Transport; Heme; Iron; Lyases; Nitrates; Oxygen; Oxygen Consumption; Pigments, Biological; Spectrum Analysis; Spirillum; Succinates | 1967 |
Tryptophan pyrrolase of rabbit intestine. D- and L-tryptophan-cleaving enzyme or enzymes.
Topics: Amidohydrolases; Ascorbic Acid; Carbon Monoxide; Catalysis; Cyanides; Heme; Intestine, Small; Intestines; Kinetics; Kynurenine; Light; Methylene Blue; Spectrophotometry; Tryptophan; Tryptophan Oxygenase | 1967 |
Carbon monoxide production associated with ineffective erythropoiesis.
Topics: Adolescent; Adult; Aged; Anemia; Anemia, Sideroblastic; Bile Pigments; Bilirubin; Carbon Isotopes; Carbon Monoxide; Chromium Isotopes; Erythropoiesis; Feces; Female; Glycine; Heme; Hemoglobinometry; Humans; Iron; Iron Isotopes; Leukopenia; Male; Middle Aged; Porphyrias; Thalassemia | 1967 |
Structure, function and evolution of turtle hemoglobins. 3. Oxygenation properties.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry, Physical; Heme; Hemoglobins; Hemolysis; Hydrogen-Ion Concentration; Methemoglobin; Oxidation-Reduction; Oxygen; Protein Binding; Respiration; Species Specificity; Temperature; Thermodynamics; Turtles | 1967 |
Carbon monoxide-driven reduction of ferric heme and heme proteins.
Topics: Animals; Carbon Monoxide; Electron Transport Complex IV; Heme; Hemeproteins; Hemoglobin A; Humans; Kinetics; Oxidation-Reduction; Spectrophotometry | 1984 |
The nature of species prepared by photolysis of half-reduced, fully reduced and fully reduced carbonmonoxy-cytochrome c-551 peroxidase from Pseudomonas aeruginosa.
Topics: Carbon Monoxide; Circular Dichroism; Cytochrome-c Peroxidase; Heme; Magnetics; Oxidation-Reduction; Peroxidases; Photolysis; Pseudomonas aeruginosa; Temperature | 1984 |
Spectroscopic studies on bleomycin-iron complexes with carbon monoxide, nitric oxide, isocyanide, azide, and cyanide and comparison with iron-porphyrin complexes.
Topics: Azides; Bleomycin; Carbon Monoxide; Cyanides; DNA; Electron Spin Resonance Spectroscopy; Heme; Iron; Magnetic Resonance Spectroscopy; Nitric Oxide; Nitriles; Oxidation-Reduction; Spectrometry, Gamma | 1982 |
Cytochrome a-type terminal oxidase derived from Thiobacillus novellus. Molecular and enzymatic properties.
Topics: Amino Acids; Carbon Monoxide; Copper; Electron Transport Complex IV; Heme; Macromolecular Substances; Molecular Weight; Oxidation-Reduction; Protein Binding; Species Specificity; Spectrophotometry; Thiobacillus | 1980 |
Resonance Raman spectra of Pseudomonas cytochrome c peroxidase.
Topics: Carbon Monoxide; Cytochrome-c Peroxidase; Heme; Iron; Ligands; Oxidation-Reduction; Peroxidases; Protein Binding; Protein Conformation; Pseudomonas aeruginosa; Spectrum Analysis, Raman | 1980 |
Studies on heme d1 extracted from Pseudomonas aeruginosa nitrite reductase.
Topics: Carbon Monoxide; Cyanides; Dithionite; Electron Spin Resonance Spectroscopy; Heme; Hydrogen-Ion Concentration; Imidazoles; Iron; NADH, NADPH Oxidoreductases; Nitric Oxide; Nitrite Reductases; Protein Binding; Pseudomonas aeruginosa; Spectrophotometry | 1981 |
Cytochrome oxidase (a3) heme and copper observed by low-temperature Fourier transform infrared spectroscopy of the CO complex.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Copper; Electron Transport Complex IV; Fourier Analysis; Heme; Mitochondria, Heart; Spectrophotometry, Infrared | 1981 |
Loss of haem and haemoproteins during the generation of superoxide anion and hydrogen peroxide: a pathway not involving production of carbon monoxide.
Topics: Animals; Anions; Azides; Bile Pigments; Carbon Monoxide; Erythrocytes; Fumarates; Heme; Hemeproteins; Horses; Hydrogen Peroxide; Oxygen; Potassium Cyanide; Sodium Azide; Superoxides; Xanthine Oxidase | 1981 |
[Low potential c-type cytochrome of Thiocapsa roseopersicina].
Topics: Carbon Monoxide; Chromatiaceae; Cytochrome c Group; Heme; Oxidation-Reduction; Potentiometry; Spectrophotometry | 1982 |
Evidence for siroheme-Fe4S4 interaction in spinach ferredoxin-sulfite reductase.
Topics: Arabidopsis Proteins; Carbon Monoxide; Cyanides; Electron Spin Resonance Spectroscopy; Ferric Compounds; Heme; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Plants; Spectrophotometry; Sulfite Reductase (Ferredoxin) | 1982 |
A comparison of the heme electronic states in equilibrium and nonequilibrium protein conformations of high-spin ferrous hemoproteins. Low temperature magnetic circular dichroism studies.
Topics: Animals; Carbon Monoxide; Cattle; Circular Dichroism; Electron Transport Complex IV; Heme; Hemeproteins; Hemoglobins; Horseradish Peroxidase; Humans; Kinetics; Mitochondria, Heart; Myoglobin; Protein Binding; Protein Conformation; Whales | 1982 |
Electron paramagnetic resonance and optical evidence for interaction between siroheme and Fe4S4 prosthetic groups in complexes of Escherichia coli sulfite reductase hemoprotein with added ligands.
Topics: Arsenic; Arsenites; Carbon Monoxide; Cyanides; Dimethyl Sulfoxide; Electron Spin Resonance Spectroscopy; Escherichia coli; Ferrous Compounds; Guanidines; Heme; Iron; Ligands; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Spectrophotometry; Sulfides; Sulfite Reductase (NADPH); Sulfur; Urea | 1983 |
Mössbauer studies of Escherichia coli sulfite reductase complexes with carbon monoxide and cyanide. Exchange coupling and intrinsic properties of the [4Fe-4S] cluster.
Topics: Carbon Monoxide; Cyanides; Electron Spin Resonance Spectroscopy; Escherichia coli; Heme; Iron-Sulfur Proteins; Mathematics; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors | 1983 |
Resolution of bovine heart cytochrome c oxidase into smaller complexes by controlled subunit denaturation.
Topics: Animals; Carbon Monoxide; Catalysis; Cattle; Chemical Phenomena; Chemistry; Electron Transport Complex IV; Heme; Myocardium; Oxidation-Reduction; Potassium Cyanide; Protein Denaturation | 1984 |
Terminal oxidases of Escherichia coli aerobic respiratory chain. I. Purification and properties of cytochrome b562-o complex from cells in the early exponential phase of aerobic growth.
Topics: Aerobiosis; Carbon Monoxide; Copper; Cytochrome b Group; Cytochromes; Escherichia coli; Escherichia coli Proteins; Heme; Iron; Kinetics; Molecular Weight; Multienzyme Complexes; Oxygen Consumption; Phospholipids; Quinone Reductases; Spectrophotometry | 1984 |
Methene bridge carbon atom elimination in oxidative heme degradation catalyzed by heme oxygenase and NADPH-cytochrome P-450 reductase.
Topics: Animals; Biliverdine; Bridged-Ring Compounds; Carbon; Carbon Monoxide; Catalysis; Chemical Phenomena; Chemistry; Heme; Heme Oxygenase (Decyclizing); Liver; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Spleen; Swine | 1984 |
Effect of ovulation on haem metabolism in rabbits.
Topics: Aminolevulinic Acid; Animals; Carbon Monoxide; Estrus; Female; Glycine; Heme; Ovulation; Pregnancy; Rabbits | 1984 |
Tension at the heme: a mathematical treatment of hemoglobin cooperativity.
Topics: Carbon Monoxide; Heme; Hemoglobins; Ligands; Mathematics; Models, Molecular; Oxygen; Thermodynamics | 1984 |
Linear free-energy relationships in binding of oxygen and carbon monoxide with heme model compounds and heme proteins.
Topics: Amides; Carbon Monoxide; Chemical Phenomena; Chemistry; Ethers; Heme; Hemeproteins; Hydrogen Bonding; Kinetics; Molecular Conformation; Oxidation-Reduction; Oxygen; Protein Binding; Thermodynamics | 1984 |
Anomalous pH dependence of the heme-bound carbon monoxide spectroscopic properties in the Glycera dibranchiata monomer hemoglobin fraction compared to vertebrate hemoglobins.
Topics: Animals; Carbon Monoxide; Carboxyhemoglobin; Heme; Hemoglobins; Horses; Humans; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Polychaeta; Rabbits; Species Specificity; Spectrophotometry, Infrared | 1984 |
Femtosecond photolysis of CO-ligated protoheme and hemoproteins: appearance of deoxy species with a 350-fsec time constant.
Topics: Carbon Monoxide; Carboxyhemoglobin; Heme; Hemoglobins; Humans; Kinetics; Lasers; Myoglobin; Photolysis | 1983 |
Side-chain cleavage of C21 steroids by testicular microsomal cytochrome P-450 (17 alpha-hydroxylase/lyase): involvement of heme.
Topics: Aldehyde-Lyases; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Male; Microsomes; Steroid 17-alpha-Hydroxylase; Steroid Hydroxylases; Steroids; Substrate Specificity; Testis | 1983 |
Resonance Raman studies of carbon monoxide binding to iron "picket fence" porphyrin with unhindered and hindered axial bases. An inverse relationship between binding affinity and the strength of iron-carbon bond.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Hemoglobins; Imidazoles; Iron; Ligands; Metalloporphyrins; Models, Biological; Spectrum Analysis, Raman | 1983 |
Resonance Raman detection of Fe-CO stretching and Fe-C-O bending vibrations in sterically hindered carbonmonoxy "strapped hemes". A structural probe of Fe-C-O distortion.
Topics: Carbon Monoxide; Heme; Hemeproteins; Iron; Kinetics; Mathematics; Models, Biological; Molecular Conformation; Spectrum Analysis, Raman; Structure-Activity Relationship | 1983 |
Isolation of partly heme devoid but not fully carbon monoxide reacting cytochrome b, from beef heart mitochondria.
Topics: Animals; Carbon Monoxide; Cattle; Cytochrome b Group; Heme; Methods; Mitochondria, Heart; Spectrophotometry | 1983 |
The effect of tin protoporphyrin on the bilirubin production rate in newborn rats.
Topics: Aging; Animals; Animals, Newborn; Bilirubin; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Kinetics; Liver; Lung; Metalloporphyrins; Porphyrins; Protoporphyrins; Rats; Rats, Inbred Strains; Spleen | 1983 |
Kinetic study of CO and O2 binding to horse heart myoglobin reconstituted with synthetic hemes lacking methyl and vinyl side chains.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Horses; Kinetics; Myocardium; Myoglobin; Oxygen; Protein Binding; Structure-Activity Relationship | 1984 |
Evidence for a peroxide-initiated free radical mechanism of prostaglandin biosynthesis.
Topics: Animals; Arachidonic Acids; Carbon Monoxide; Catalysis; Cattle; Cyclooxygenase Inhibitors; Free Radicals; Glutathione Peroxidase; Heme; Naphthols; Peroxides; Phenols; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Sodium Cyanide | 1980 |
A new intermediate of heme degradation catalyzed by the heme oxygenase system.
Topics: Animals; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Kinetics; Microsomes; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Spectrophotometry; Spleen; Swine | 1980 |
The step of carbon monoxide liberation in the sequence of heme degradation catalyzed by the reconstituted microsomal heme oxygenase system.
Topics: Bilirubin; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Microsomes; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Spectrophotometry | 1982 |
Ab initio calculations of electron distributions in heme-CO models.
Topics: Carbon Monoxide; Electron Transport; Heme; Kinetics; Molecular Conformation; Oxidation-Reduction | 1983 |
Characterization of a new type of dissimilatory sulfite reductase present in Thermodesulfobacterium commune.
Topics: Amino Acid Sequence; Amino Acids; Bacteria; Carbon Monoxide; Heme; Iron; Kinetics; Macromolecular Substances; Molecular Weight; Oxidoreductases; Oxidoreductases Acting on Sulfur Group Donors; Spectrophotometry; Sulfur | 1983 |
Proton nuclear magnetic resonance studies of isonitrile-heme protein complexes.
Topics: Animals; Carbon Monoxide; Cyanides; Heme; Hemoglobins; Humans; Macromolecular Substances; Magnetic Resonance Spectroscopy; Myoglobin; Nitriles; Thermodynamics; Valine; Whales | 1983 |
Heme P460 of hydroxylamine oxidoreductase of Nitrosomonas. Reaction with CO and H2O2.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Hydrogen Peroxide; Kinetics; Nitrites; Nitrosomonas; Oxidation-Reduction; Oxidoreductases; Protein Binding | 1983 |
Trace gas analysis in bilirubin metabolism: a technical review and current state of the art.
Topics: Adolescent; Animals; Bilirubin; Breast Feeding; Breath Tests; Carbon Monoxide; Carboxyhemoglobin; Energy Intake; Female; Heme; Humans; Infant; Infant, Newborn; Infant, Premature; Pregnancy; Pregnancy in Diabetics; Rats | 1982 |
Binding of O2 and CO to hemes and hemoproteins.
Topics: Carbon Monoxide; Carboxyhemoglobin; Chemical Phenomena; Chemistry; Heme; Hemeproteins; Hemoglobins; Kinetics; Models, Chemical; Oxygen; Oxyhemoglobins; Thermodynamics | 1980 |
Kinetics and mechanism of heme-induced refolding of human alpha-globin.
Topics: Carbon Monoxide; Circular Dichroism; Cyanides; Globins; Heme; Humans; Kinetics; Macromolecular Substances; Oxidation-Reduction; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry | 1981 |
Carbon monoxide binding kinetics in "capped" porphyrin compounds.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Heme; Hemeproteins; Iron; Porphyrins; Structure-Activity Relationship | 1982 |
Covalent binding of carbon tetrachloride metabolites to the heme moiety of cytochrome P-450 and its degradation products.
Topics: Animals; Carbon Monoxide; Carbon Tetrachloride; Cytochrome P-450 Enzyme System; Free Radicals; Heme; Lipid Peroxides; Male; Microsomes, Liver; Protein Binding; Protoporphyrins; Rats; Rats, Inbred Strains | 1982 |
Effects of solvent on the absorption maxima of five-coordinate heme complexes and carbon monoxide-heme complexes as models for the differential spectral properties of hemoglobins and myoglobins.
Topics: Carbon Monoxide; Detergents; Heme; Hemoglobins; Hemoglobins, Abnormal; Humans; Hydrogen-Ion Concentration; Myoglobin; Solvents; Spectrum Analysis | 1982 |
Metabolism of carbon monoxide by the colonic flora of humans.
Topics: Aerobiosis; Anaerobiosis; Bacteria; Carbon Monoxide; Colon; Feces; Heme; Humans | 1982 |
Resolution of multiple heme centers of hydroxylamine oxidoreductase from Nitrosomonas. 2. Mössbauer spectroscopy.
Topics: Carbon Monoxide; Heme; Nitrosomonas; Oxidation-Reduction; Oxidoreductases; Spectrometry, Gamma | 1982 |
Oxygen- and carbon monoxide-binding kinetic parameters for liposomal heme under semi-physiological condition.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Dimyristoylphosphatidylcholine; Heme; Hemoglobins; Hydrogen-Ion Concentration; Liposomes; Myoglobin; Oxygen; Phosphatidylcholines; Photochemistry; Spectrophotometry, Ultraviolet | 1982 |
Spectral and carbon monoxide binding properties of Fe(II) picket-fence porphyrin and protoheme bound to liposomes.
Topics: Animals; Carbon Monoxide; Heme; Liposomes; Mesoporphyrins; Phosphatidylcholines; Porphyrins; Sheep; Spectrophotometry; Swine | 1982 |
Flash photolysis study of ligand binding by modified myoglobins at low temperatures.
Topics: Binding Sites; Carbon Monoxide; Deuteroporphyrins; Heme; Kinetics; Ligands; Mesoporphyrins; Models, Chemical; Myoglobin; Photolysis | 1980 |
The production of 14CO following the administration of 2-[14C] glycine in normal subjects determined by an oxygen washout technique.
Topics: Carbon Monoxide; Carbon Radioisotopes; Erythropoiesis; Glycine; Heme; Humans; Liver; Male; Middle Aged; Oxygen; Time Factors | 1980 |
Studies on the isolation of intermediate compounds between hemoglobin and ligands.
Topics: Carbon Monoxide; Heme; Hemoglobins; Humans; Ligands; Macromolecular Substances; Oxidation-Reduction | 1981 |
Resonance Raman spectra of myoglobins reconstituted with spirographis and isospirographis hemes and iron 2,4-diformylprotoporphyrin IX. Effect of formyl substitution at the heme periphery.
Topics: Animals; Carbon Monoxide; Heme; Iron; Molecular Conformation; Myoglobin; Porphyrins; Protein Conformation; Protoporphyrins; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Whales | 1980 |
Degradation of endogenous hepatic heme by pathways not yielding carbon monoxide. Studies in normal rat liver and in primary hepatocyte culture.
Topics: Animals; Biotransformation; Carbon Monoxide; Cells, Cultured; Heme; Kidney; Liver; Male; Nephrectomy; Rats | 1980 |
Transient Raman study of CO-haemoprotein photolysis: origin of the quantum yield.
Topics: Binding Sites; Carbon Monoxide; Carboxyhemoglobin; Heme; Hemoglobins; Humans; Kinetics; Ligands; Myoglobin; Photolysis; Protein Binding; Spectrum Analysis, Raman | 1980 |
Ligand-dependent heme-protein interactions in human hemoglobin studied by Fourier transform infrared spectroscopy. Effects of quaternary structure on alpha chain tertiary structure measured at the alpha-104(G11) cysteine-SH.
Topics: Azides; Carbon Monoxide; Cyanides; Cysteine; Fourier Analysis; Heme; Hemoglobins; Humans; Ligands; Macromolecular Substances; Nitric Oxide; Oxyhemoglobins; Protein Binding; Protein Conformation; Spectrophotometry, Infrared | 1980 |
Preparation of a novel 13C-labelled heme protein.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Hematoporphyrins; Heme; Hemeproteins; Iron; Isotope Labeling; Magnetic Resonance Spectroscopy; Myoglobin; Protein Binding; Protein Conformation; Whales; Zinc | 1980 |
Isomeric incorporation of the haem into monomeric haemoglobins of Chironomus thummi thummi 3. Comparative study of components, I, III and IV.
Topics: Allosteric Regulation; Animals; Carbon Monoxide; Chironomidae; Diptera; Erythrocruorins; Heme; Hemoglobins; Histidine; Hydrogen-Ion Concentration; Isomerism; Macromolecular Substances; Magnetic Resonance Spectroscopy; Oxygen | 1980 |
Isomeric incorporation of the haem into monomeric haemoglobins of Chironomus thummi thummi. 1. Isolation of chemically homogeneous haemoglobins. Evidence for the isomerism of the haem in the component III.
Topics: Animals; Carbon Monoxide; Chironomidae; Diptera; Erythrocruorins; Heme; Hemoglobins; Histidine; Isomerism; Larva; Macromolecular Substances; Magnetic Resonance Spectroscopy; Protein Conformation | 1980 |
Isomeric incorporation of the Haem into monomeric haemoglobins of Chironomus thummi thummi. 2. The Bohr effect of the component III explained on a molecular basis and functional differences between the two isomeric structures.
Topics: Allosteric Regulation; Animals; Carbon Monoxide; Chironomidae; Diptera; Erythrocruorins; Heme; Hemoglobins; Histidine; Hydrogen-Ion Concentration; Isomerism; Macromolecular Substances; Magnetic Resonance Spectroscopy; Protein Conformation; Thermodynamics | 1980 |
The role of diffusion in limiting the rate of ligand binding to hemoglobin.
Topics: Animals; Carbon Monoxide; Diffusion; Heme; Hemoglobins; Kinetics; Ligands; Nitric Oxide; Protein Binding; Tuna | 1980 |
Endogenous carbon monoxide production after bicycle exercise in healthy subjects and in patients with hereditary spherocytosis.
Topics: Adult; Bilirubin; Carbon Monoxide; Carboxyhemoglobin; Female; Heme; Hemolysis; Humans; Lung Volume Measurements; Male; Middle Aged; Physical Exertion; Spherocytosis, Hereditary | 1980 |
Quantification of ineffective erythropoiesis in megaloblastic anaemia by determination of endogenous production of 14CO after administration of glycine-2-14C.
Topics: Aged; Anemia, Pernicious; Blood Cell Count; Carbon Monoxide; Erythrocyte Indices; Erythropoiesis; Female; Glycine; Heme; Hemoglobins; Humans; Male; Middle Aged | 1980 |
Solvent viscosity and protein dynamics.
Topics: Carbon Monoxide; Heme; Kinetics; Models, Biological; Myoglobin; Oxygen; Protein Binding; Protein Conformation; Solvents; Viscosity | 1980 |
The interaction of heme-hemopexin with CO.
Topics: Animals; Carbon Monoxide; Heme; Hemopexin; Kinetics; Oxidation-Reduction; Protein Binding; Rabbits; Spectrophotometry | 1981 |
L-arginine and calmodulin regulation of the heme iron reactivity in neuronal nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Arginine; Binding Sites; Calmodulin; Carbon Monoxide; Cells, Cultured; Heme; Humans; Iron; Kinetics; Neurons; Nitric Oxide Synthase | 1994 |
Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group. Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Biopterins; Carbon Monoxide; Cerebellum; Citrulline; Cyanides; Heme; NADP; Neurons; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Oxyhemoglobins; Rats; Sulfhydryl Compounds; Superoxide Dismutase | 1994 |
Mechanism of ligand binding to Ni(II)-Fe(II) hybrid hemoglobins.
Topics: Allosteric Regulation; Binding Sites; Carbon Monoxide; Computer Graphics; Ferrous Compounds; Heme; Hemoglobins; Hydrogen-Ion Concentration; Kinetics; Ligands; Models, Molecular; Nickel; Nitric Oxide; Oxygen | 1995 |
Laser photolysis behavior of ferrous horseradish peroxidase with carbon monoxide and cyanide: effects of mutations in the distal heme pocket.
Topics: Arginine; Base Sequence; Carbon Monoxide; Cyanides; Ferrous Compounds; Heme; Histidine; Horseradish Peroxidase; Kinetics; Lasers; Molecular Sequence Data; Mutagenesis, Site-Directed; Photolysis; Recombinant Proteins; Spectrum Analysis | 1995 |
Compressibility of the heme pocket of substrate analogue complexes of cytochrome P-450cam-CO. The effect of hydrostatic pressure on the Soret band.
Topics: Camphor 5-Monooxygenase; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Heme; Hydrostatic Pressure; Mixed Function Oxygenases | 1995 |
Alteration of axial coordination by protein engineering in myoglobin. Bisimidazole ligation in the His64-->Val/Val68-->His double mutant.
Topics: Animals; Carbon Monoxide; Crystallography, X-Ray; Electron Spin Resonance Spectroscopy; Heme; Histidine; Humans; Imidazoles; Ligands; Models, Molecular; Mutation; Myoglobin; Protein Engineering; Spectrophotometry; Spectrum Analysis; Swine; Valine; X-Rays | 1995 |
Cytochrome bd oxidase from Azotobacter vinelandii. Purification and quantitation of ligand binding to the oxygen reduction site.
Topics: Azotobacter vinelandii; Binding Sites; Carbon Monoxide; Cyanides; Cytochrome b Group; Cytochromes; Electron Spin Resonance Spectroscopy; Electron Transport Chain Complex Proteins; Escherichia coli Proteins; Heme; Kinetics; Ligands; Nitric Oxide; Oxidation-Reduction; Oxidoreductases; Oxygen; Spectrophotometry | 1995 |
Biochemistry. New angle for classic tale of respiratory protein and oxygen.
Topics: Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Heme; Myoglobin; Oxygen; Spectrophotometry, Infrared; Water | 1995 |
Oxidation of NG-hydroxy-L-arginine by nitric oxide synthase: evidence for the involvement of the heme in catalysis.
Topics: Amino Acid Oxidoreductases; Anaerobiosis; Animals; Arginine; Carbon Monoxide; Catalysis; Cell Line; Heme; Kinetics; Macrophages; Mice; Nitric Oxide Synthase; Oxidation-Reduction; Spectrophotometry; Substrate Specificity | 1993 |
Heme coordination and structure of the catalytic site in nitric oxide synthase.
Topics: Amino Acid Oxidoreductases; Animals; Binding Sites; Brain; Carbon Monoxide; Cell Line; Cloning, Molecular; Heme; Kidney; Nitric Oxide Synthase; Oxidation-Reduction; Protein Binding; Protein Conformation; Rats; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; Transfection | 1993 |
The distal residue-CO interaction in carbonmonoxy myoglobins: a molecular dynamics study of two distal histidine tautomers.
Topics: Animals; Biophysical Phenomena; Biophysics; Carbon Monoxide; Crystallography, X-Ray; Electrochemistry; Heme; Histidine; Ligands; Models, Molecular; Molecular Structure; Myoglobin; Protein Structure, Tertiary; Spectrophotometry, Infrared; Stereoisomerism; Thermodynamics | 1994 |
Basis of guanylate cyclase activation by carbon monoxide.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Enzyme Activation; Guanylate Cyclase; Heme; Humans; Kinetics; Lung; Serum Albumin; Spectrophotometry; Time Factors | 1995 |
Studies of the heme coordination and ligand binding properties of soluble guanylyl cyclase (sGC): characterization of Fe(II)sGC and Fe(II)sGC(CO) by electronic absorption and magnetic circular dichroism spectroscopies and failure of CO to activate the enz
Topics: Animals; Carbon Monoxide; Cattle; Circular Dichroism; Enzyme Activation; Ferrous Compounds; Glycerol; Guanylate Cyclase; Heme; Histidine; Hydrogen-Ion Concentration; Ligands; Nitric Oxide | 1995 |
Vascular smooth muscle cell heme oxygenases generate guanylyl cyclase-stimulatory carbon monoxide.
Topics: Animals; Aorta; Arsenites; Blood Platelets; Blotting, Western; Carbon Monoxide; Cells, Cultured; Culture Media, Conditioned; Guanylate Cyclase; Heme; Heme Oxygenase (Decyclizing); Hemin; Muscle, Smooth, Vascular; Rats; Sodium Compounds | 1995 |
Terminal oxidases of the bb- and caa3-types in Bacillus sp. FTU.
Topics: Bacillus; Carbon Monoxide; Cell Membrane; Chromatography, High Pressure Liquid; Copper; Electron Transport Complex IV; Escherichia coli; Heme; Isoenzymes; Lasers; Photolysis; Spectrophotometry | 1995 |
Soluble guanylate cyclase from bovine lung: activation with nitric oxide and carbon monoxide and spectral characterization of the ferrous and ferric states.
Topics: Animals; Carbon Monoxide; Cattle; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Ferric Compounds; Ferrous Compounds; Guanylate Cyclase; Heme; Lung; Nitric Oxide; Spectrophotometry, Ultraviolet | 1994 |
Identification of histidine 25 as the heme ligand in human liver heme oxygenase.
Topics: Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Histidine; Humans; Ligands; Liver; Oxidation-Reduction; Point Mutation; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman | 1994 |
Low-temperature magnetic circular dichroism investigation of the active site of chloroperoxidase.
Topics: Binding Sites; Carbon Monoxide; Chloride Peroxidase; Circular Dichroism; Cold Temperature; Heme; Hydrogen-Ion Concentration; Ligands; Mitosporic Fungi; Oxidation-Reduction; Photolysis; Protein Conformation; Sulfhydryl Compounds | 1994 |
Interactions of dihydralazine with cytochromes P4501A: a possible explanation for the appearance of anti-cytochrome P4501A2 autoantibodies.
Topics: Animals; Arylamine N-Acetyltransferase; Autoantibodies; Binding Sites; Biotransformation; Blotting, Western; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dihydralazine; Heme; Iron; Isoenzymes; Light; Male; Microsomes, Liver; NADP; Rats; Rats, Sprague-Dawley | 1994 |
Synthetic hemes.
Topics: Binding Sites; Blood Substitutes; Carbon Monoxide; Erythrocytes; Heme; Hemoglobins; Humans; In Vitro Techniques; Kinetics; Lipid Bilayers; Magnetic Resonance Spectroscopy; Microspheres; Models, Chemical; Molecular Structure; Myoglobin; Oxygen; Spectroscopy, Mossbauer | 1994 |
Diurnal rhythm of heme turnover assessed by breath carbon monoxide concentration measurements.
Topics: Aged; Breath Tests; Carbon Monoxide; Circadian Rhythm; Female; Heme; Humans; Male; Middle Aged | 1994 |
Ro 09-1470 is a selective inhibitor of P-450 lanosterol C-14 demethylase of fungi.
Topics: Animals; Antifungal Agents; Carbon Monoxide; Cholesterol; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Fluconazole; Fungal Proteins; Glycine; Heme; Ketoconazole; Liver; Male; Microsomes, Liver; Oxidoreductases; Pyrans; Rats; Rats, Sprague-Dawley; Saccharomyces cerevisiae; Sensitivity and Specificity; Sterol 14-Demethylase | 1993 |
Assignment of the 13C and 13CO resonances for Rhodobacter capsulatus ferrocytochrome c2 using double-resonance and triple-resonance NMR spectroscopy.
Topics: Carbon Isotopes; Carbon Monoxide; Cytochrome c Group; Cytochromes c2; Heme; Magnetic Resonance Spectroscopy; Protein Structure, Secondary; Rhodobacter capsulatus | 1994 |
Heme-heme oxygenase complex: structure and properties of the catalytic site from resonance Raman scattering.
Topics: Animals; Binding Sites; Carbon Monoxide; Catalysis; Heme; Heme Oxygenase (Decyclizing); Protein Conformation; Rats; Scattering, Radiation; Spectrum Analysis, Raman | 1994 |
Binding of heme-CO to bovine and porcine beta-lactoglobulins.
Topics: Animals; Carbon Monoxide; Cattle; Energy Transfer; Heme; Hydrogen-Ion Concentration; Kinetics; Lactoglobulins; Protein Binding; Spectrometry, Fluorescence; Spectrophotometry; Swine | 1994 |
Heme binding to calmodulin, troponin C, and parvalbumin, as a probe of calcium-dependent conformational changes.
Topics: Animals; Brain; Calcium; Calmodulin; Carbon Monoxide; Cattle; Chromatography, High Pressure Liquid; Heme; Intercellular Signaling Peptides and Proteins; Kinetics; Muscles; Parvalbumins; Peptide Fragments; Peptides; Protein Binding; Protein Conformation; Spectrometry, Fluorescence; Spectrophotometry; Troponin; Troponin C; Wasp Venoms | 1993 |
Fast events in protein folding initiated by nanosecond laser photolysis.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbon Monoxide; Cytochrome c Group; Guanidine; Guanidines; Heme; Horses; Kinetics; Lasers; Methionine; Photolysis; Protein Conformation; Protein Folding; Protein Structure, Secondary; Spectrophotometry; Time Factors | 1993 |
Time-resolved absorption and magnetic circular dichroism spectroscopy of cytochrome c3 from Desulfovibrio.
Topics: Biophysical Phenomena; Biophysics; Carbon Monoxide; Circular Dichroism; Cytochrome c Group; Desulfovibrio vulgaris; Heme; Kinetics; Magnetics; Photolysis; Spectrophotometry; Spectrophotometry, Ultraviolet | 1993 |
Cytochrome bo from Escherichia coli: identification of haem ligands and reaction of the reduced enzyme with carbon monoxide.
Topics: Carbon Monoxide; Copper; Cytochrome b Group; Cytochromes; Electron Spin Resonance Spectroscopy; Escherichia coli; Escherichia coli Proteins; Heme; Iron; Kinetics; Ligands; Metalloproteins; Nitric Oxide; Oxidation-Reduction; Spectrophotometry | 1993 |
Kinetic and ligand binding evidence for two heme A-based terminal oxidases in plasma membranes from Bacillus subtilis.
Topics: Ascorbic Acid; Bacillus subtilis; Carbon Monoxide; Cell Membrane; Cyanides; Dithionite; Electron Transport Complex IV; Heme; Kinetics; Octoxynol; Oxidation-Reduction; Oxygen; Photolysis; Polyethylene Glycols; Solubility; Spectrophotometry; Tetramethylphenylenediamine | 1993 |
Heme-heme interactions in a homodimeric cooperative hemoglobin. Evidence from transient Raman scattering.
Topics: Animals; Bivalvia; Carbon Monoxide; Heme; Hemoglobins; Histidine; Iron; Protein Conformation; Spectrum Analysis, Raman | 1993 |
Conformational dynamics of cytochrome P-450cam as monitored by photoacoustic calorimetry.
Topics: Calorimetry; Camphor 5-Monooxygenase; Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Kinetics; Mixed Function Oxygenases; Oxidation-Reduction; Protein Conformation; Spectrophotometry; Thermodynamics | 1993 |
Synthesis of porphinatoirons having an alkyl amphiphilic chain and their O2 binding properties in lipid bilayers.
Topics: Carbon Monoxide; Heme; Kinetics; Lipid Bilayers; Liposomes; Molecular Structure; Oxygen; Spectrophotometry | 1993 |
Determination of Fe-CO geometry in the subunits of carbonmonoxy hemoglobin M Boston using femtosecond infrared spectroscopy.
Topics: Binding Sites; Carbon Monoxide; Carboxyhemoglobin; Heme; Hemoglobin M; Humans; Iron; Photolysis; Spectrophotometry, Infrared | 1993 |
Perturbations of the distal heme pocket in human myoglobin mutants probed by infrared spectroscopy of bound CO: correlation with ligand binding kinetics.
Topics: Carbon Monoxide; Heme; Humans; In Vitro Techniques; Kinetics; Ligands; Mutagenesis, Site-Directed; Myoglobin; Spectrophotometry, Infrared; Structure-Activity Relationship | 1993 |
Redox dependent interactions of the metal sites in carbon monoxide-bound cytochrome c oxidase monitored by infrared and UV/visible spectroelectrochemical methods.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Electrochemistry; Electron Transport; Electron Transport Complex IV; Heme; In Vitro Techniques; Ligands; Metals; Molecular Probes; Myocardium; Oxidation-Reduction; Spectrophotometry; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 1996 |
Regulation of gonadotrophin-releasing hormone (GnRH) secretion by heme molecules: a regulatory role for carbon monoxide?
Topics: Animals; Carbon Monoxide; Dose-Response Relationship, Drug; Female; Gonadotropin-Releasing Hormone; Heme; Heme Oxygenase (Decyclizing); Hemin; Hypothalamus, Middle; In Vitro Techniques; Rats; Rats, Inbred Strains | 1996 |
Carbon monoxide: an endogenous modulator of the nitric oxide-cyclic GMP signaling system.
Topics: Animals; Animals, Newborn; Carbon Monoxide; Cells, Cultured; Cerebellum; Cyclic GMP; Drug Synergism; Guanylate Cyclase; Heme; Nitric Oxide; Nitric Oxide Synthase; Rats; Signal Transduction | 1996 |
Time-resolved Fourier-transform infrared studies of the cytochrome P-450cam carbonmonoxide complex bound with (1R)-camphor and (1S)-camphor substrate.
Topics: Camphor; Camphor 5-Monooxygenase; Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Mixed Function Oxygenases; Spectroscopy, Fourier Transform Infrared; Stereoisomerism; Temperature; Thermodynamics | 1996 |
Crystal structures of CO-, deoxy- and met-myoglobins at various pH values.
Topics: Animals; Anisotropy; Carbon Monoxide; Computer Graphics; Crystallization; Crystallography, X-Ray; Heme; Histidine; Hydrogen-Ion Concentration; Metmyoglobin; Models, Molecular; Myoglobin; Protein Conformation; Protein Structure, Tertiary; Whales | 1996 |
Picosecond geminate recombination of CO to the complexes calmodulin*heme-CO and calmodulin*heme-CO*melittin.
Topics: Amino Acid Sequence; Binding Sites; Calcium; Calmodulin; Carbon Monoxide; Heme; Kinetics; Melitten; Molecular Sequence Data; Photolysis; Spectrometry, Fluorescence; Spectrophotometry; Viscosity | 1996 |
Modulation of protein function by exogenous ligands in protein cavities: CO binding to a myoglobin cavity mutant containing unnatural proximal ligands.
Topics: Animals; Binding Sites; Carbon Monoxide; Cloning, Molecular; Escherichia coli; Heme; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Mutagenesis, Site-Directed; Myoglobin; Point Mutation; Protein Conformation; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Valine; Whales | 1996 |
Study of the coordination chemistry of prostaglandin G/H synthase by resonance Raman spectroscopy.
Topics: Animals; Carbon Monoxide; Circular Dichroism; Dithionite; Ferrous Compounds; Heme; Hydrogen Bonding; Male; Molecular Structure; Oxidation-Reduction; Prostaglandin-Endoperoxide Synthases; Protoporphyrins; Seminal Vesicles; Sheep; Spectrophotometry; Spectrum Analysis, Raman | 1996 |
Global mapping of structural solutions provided by the extended X-ray absorption fine structure ab initio code FEFF 6.01: structure of the cryogenic photoproduct of the myoglobin-carbon monoxide complex.
Topics: Animals; Carbon Monoxide; Computer Simulation; Crystallography, X-Ray; Heme; Histidine; Horses; Iron; Muscle, Skeletal; Myoglobin; Photolysis; Software; Spectrophotometry; Spectrum Analysis, Raman; Temperature | 1996 |
Isolation and characterization of the d1 domain of Pseudomonas aeruginosa nitrite reductase.
Topics: Amino Acid Sequence; Carbon Monoxide; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Heme; Kinetics; Macromolecular Substances; Molecular Sequence Data; Molecular Weight; Nitrite Reductases; Peptide Fragments; Photolysis; Pseudomonas aeruginosa; Spectrophotometry; Subtilisins | 1996 |
A pH-dependent polarity change at the binuclear center of reduced cytochrome c oxidase detected by FTIR difference spectroscopy of the CO adduct.
Topics: Amino Acid Sequence; Carbon Monoxide; Copper; Electron Transport Complex IV; Heme; Hydrogen-Ion Concentration; Iron; Molecular Sequence Data; Mutagenesis, Site-Directed; Rhodobacter sphaeroides; Spectroscopy, Fourier Transform Infrared | 1996 |
The association rate constant for heme binding to globin is independent of protein structure.
Topics: Animals; Apoproteins; Carbon Monoxide; Heme; Hemeproteins; Horses; Kinetics; Mutagenesis; Myoglobin; Protein Binding; Recombinant Proteins; Serum Albumin, Bovine; Sheep; Whales | 1996 |
The regulation of heme turnover and carbon monoxide biosynthesis in cultured primary rat olfactory receptor neurons.
Topics: Animals; Carbon Monoxide; Cell Differentiation; Cells, Cultured; Cyclic GMP; Heme; Heme Oxygenase (Decyclizing); Nerve Tissue; Neurons, Afferent; Olfactory Pathways; Rats; Sensory Receptor Cells | 1996 |
Redox properties of cytochrome c nitrite reductase from Desulfovibrio desulfuricans ATCC 27774.
Topics: Carbon Monoxide; Cytochromes a1; Cytochromes c1; Desulfovibrio; Electron Spin Resonance Spectroscopy; Heme; Hydrogenase; Nitrate Reductases; Oxidation-Reduction; Spectroscopy, Mossbauer; Titrimetry | 1996 |
Photoperturbation of the heme a3-CuB binuclear center of cytochrome c oxidase CO complex observed by Fourier transform infrared spectroscopy.
Topics: Animals; Carbon Monoxide; Cattle; Copper; Darkness; Electron Transport Complex IV; Heme; Light; Macromolecular Substances; Mitochondria, Heart; Models, Structural; Photochemistry; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared | 1996 |
The ferrous heme of soluble guanylate cyclase: formation of hexacoordinate complexes with carbon monoxide and nitrosomethane.
Topics: Animals; Carbon Monoxide; Cattle; Enzyme Activation; Ferrous Compounds; Flow Injection Analysis; Guanylate Cyclase; Heme; Hemeproteins; Kinetics; Lung; Nitroso Compounds; Solubility; Spectrophotometry | 1995 |
Nanosecond step-scan FTIR spectroscopy of hemoglobin: ligand recombination and protein conformational changes.
Topics: Carbon Monoxide; Carboxyhemoglobin; Heme; Hemoglobins; Humans; Kinetics; Ligands; Photolysis; Protein Conformation; Protein Structure, Tertiary; Spectroscopy, Fourier Transform Infrared | 1996 |
Heme-CO binding to tryptophan-containing calmodulin mutants.
Topics: Animals; Binding Sites; Calmodulin; Carbon Monoxide; Cattle; Energy Transfer; Heme; Models, Molecular; Mutation; Protein Binding; Spectrometry, Fluorescence; Trifluoperazine; Tryptophan | 1996 |
Photolysis of the carbon monoxide complex of myoglobin: nanosecond time-resolved crystallography.
Topics: Carbon Monoxide; Computer Simulation; Crystallography, X-Ray; Fourier Analysis; Globins; Heme; Histidine; Iron; Ligands; Myoglobin; Photolysis; Temperature; Time Factors | 1996 |
Functional interactions in cytochrome P450BM3. Fatty acid substrate binding alters electron-transfer properties of the flavoprotein domain.
Topics: Bacterial Proteins; Carbon Monoxide; Catalysis; Cytochrome c Group; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electron Transport; Escherichia coli; Fatty Acids; Flavoproteins; Heme; Hydroxylation; Lauric Acids; Mixed Function Oxygenases; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Binding; Spectrometry, Fluorescence | 1996 |
Role of the polarity of the heme environment for the CO stretch modes in cytochrome P-450cam-CO.
Topics: Camphor 5-Monooxygenase; Carbon Monoxide; Chemical Phenomena; Chemistry, Physical; Electrochemistry; Heme; Molecular Structure; Protein Binding; Pseudomonas putida; Spectroscopy, Fourier Transform Infrared; Water | 1996 |
The binding of carbon monoxide and nitric oxide to leghaemoglobin in comparison with other haemoglobins.
Topics: Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Electrochemistry; Fabaceae; Heme; Kinetics; Leghemoglobin; Ligands; Models, Molecular; Molecular Structure; Nitric Oxide; Plants, Medicinal; Protein Binding; Protein Structure, Secondary | 1996 |
A flash-photolysis study of the reactions of a caa3-type cytochrome oxidase with dioxygen and carbon monoxide.
Topics: Animals; Carbon Monoxide; Cattle; Electron Transport; Electron Transport Complex IV; Heme; Oxygen; Photolysis; Spectrophotometry, Atomic | 1996 |
A sensitive microassay reveals marked regional differences in the capacity of rat brain to generate carbon monoxide.
Topics: Animals; Bilirubin; Brain; Carbon Monoxide; Cerebellum; Chromatography, Thin Layer; Heme; Heme Oxygenase (Decyclizing); Male; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Rats; Rats, Wistar; Sensitivity and Specificity; Tissue Distribution; Toluene | 1995 |
Nanosecond crystallographic snapshots of protein structural changes.
Topics: Carbon Monoxide; Computer Simulation; Crystallography, X-Ray; Heme; Ligands; Models, Molecular; Myoglobin; Photolysis; Protein Conformation; Time Factors | 1996 |
Absorption spectral studies on heme ligand interactions of P-450nor.
Topics: Binding, Competitive; Camphor 5-Monooxygenase; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ferric Compounds; Ferrous Compounds; Fusarium; Heme; Imidazoles; Ligands; Nitriles; Oxidoreductases; Pyridines; Spectrophotometry; Titrimetry | 1997 |
Theoretical study of the electrostatic and steric effects on the spectroscopic characteristics of the metal-ligand unit of heme proteins. 2. C-O vibrational frequencies, 17O isotropic chemical shifts, and nuclear quadrupole coupling constants.
Topics: Carbon Monoxide; Heme; Hemeproteins; Hemoglobins; Histidine; Iron; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Myoglobin; Oxygen; Oxygen Isotopes; Porphyrins; Protein Conformation | 1997 |
Photochemical action spectra, not absorption spectra, allow identification of the oxygen sensor in the carotid body.
Topics: Animals; Binding, Competitive; Carbon Dioxide; Carbon Monoxide; Carotid Body; Cats; Electron Transport Complex IV; Energy Metabolism; Heme; Mitochondria; Models, Biological; Oxygen; Oxygen Consumption; Photochemistry; Protein Binding; Synaptic Transmission | 1996 |
On the origin of heme absorption band shifts and associated protein structural relaxation in myoglobin following flash photolysis.
Topics: Animals; Carbon Monoxide; Heme; Horses; Models, Molecular; Myoglobin; Photolysis; Protein Conformation; Spectrophotometry, Atomic; Spectrophotometry, Infrared; Temperature; Whales | 1997 |
Interactions between substrate analogues and heme ligands in nitric oxide synthase.
Topics: Animals; Binding Sites; Brain; Carbon Monoxide; Citrulline; Cytochrome P-450 Enzyme System; Drug Interactions; Heme; Ligands; Nitric Oxide Synthase; Protein Conformation; Rats; Spectrum Analysis, Raman; Substrate Specificity | 1997 |
Role of carbon monoxide in heme-induced vasodilation.
Topics: Animals; Arterioles; Carbon Monoxide; Heme; Lysine; Male; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Vasodilation | 1997 |
Kinetics of CO ligation with nitric-oxide synthase by flash photolysis and stopped-flow spectrophotometry.
Topics: Animals; Arginine; Carbon Monoxide; Heme; Kinetics; Nitric Oxide Synthase; Photolysis; Rats; Spectrophotometry | 1997 |
Remarkable functional aspects of myoglobin induced by diazaheme prosthetic group.
Topics: Acids; Azo Compounds; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Heme; Iron; Kinetics; Mesoporphyrins; Myoglobin; Nitric Oxide; Oxygen; Phthalic Acids; Porphyrins | 1997 |
A comparison between molecular dynamics and X-ray results for dissociated CO in myoglobin.
Topics: Algorithms; Binding Sites; Carbon Monoxide; Computer Simulation; Crystallography, X-Ray; Heme; Models, Molecular; Myoglobin; Photolysis; Probability; Protein Conformation; Software; Thermodynamics | 1997 |
Reductive activation of 1,1-dichloro-1-fluoroethane (HCFC-141b) by phenobarbital- and pyridine-induced rat liver microsomal cytochrome P450.
Topics: Alkenes; Anaerobiosis; Animals; Biotransformation; Carbon Monoxide; Chlorofluorocarbons; Chlorofluorocarbons, Ethane; Cyclic N-Oxides; Cytochrome P-450 CYP2B1; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Glutathione; Heme; Male; Microsomes, Liver; NADP; Nitrogen Oxides; Oxidation-Reduction; Phenobarbital; Pyridines; Rats; Rats, Wistar | 1996 |
Comparative Fourier transform infrared studies of the secondary structure and the CO heme ligand environment in cytochrome P-450cam and cytochrome P-420cam.
Topics: Binding Sites; Camphor 5-Monooxygenase; Carbon Monoxide; Heating; Heme; Ligands; Protein Folding; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Thiocyanates | 1997 |
Effects of decyl-aurachin D and reversed electron transfer in cytochrome bd.
Topics: Azotobacter vinelandii; Carbon Monoxide; Cytochrome b Group; Cytochromes; Electron Transport; Electron Transport Chain Complex Proteins; Enzyme Inhibitors; Escherichia coli Proteins; Heme; Kinetics; Oxidation-Reduction; Oxidoreductases; Quinolones; Structure-Activity Relationship | 1997 |
Internal electron transfer in Cu-heme oxidases. Thermodynamic or kinetic control?
Topics: Binding Sites; Carbon Monoxide; Copper; Electron Transport; Electron Transport Complex IV; Heme; Kinetics; Models, Molecular; Nitric Oxide; Oxygen; Ruthenium Compounds; Thermodynamics | 1997 |
Circular dichroism spectroscopy of Lucina I hemoglobin.
Topics: Animals; Carbon Monoxide; Circular Dichroism; Crystallography, X-Ray; Cyanides; Heme; Hemoglobins; Hemoglobins, Abnormal; Iron; Mollusca; Oxyhemoglobins; Spectrophotometry; Spectrophotometry, Ultraviolet; Sulfides | 1997 |
1H-NMR study of diamagnetic cytochrome P450cam: assignment of heme resonances and substrate dependance of one cysteinate beta proton.
Topics: Binding Sites; Camphor 5-Monooxygenase; Carbon Monoxide; Cysteine; Heme; Hydrogen; Iron; Magnetic Resonance Spectroscopy; Magnetics; Models, Molecular; Oxidation-Reduction; Protein Conformation; Recombinant Proteins; Substrate Specificity | 1997 |
Vectorial nature of redox Bohr effects in bovine heart cytochrome c oxidase.
Topics: Animals; Carbon Monoxide; Cattle; Copper; Electron Transport Complex IV; Heme; Hydrogen-Ion Concentration; Kinetics; Liposomes; Mitochondria, Heart; Oxidation-Reduction | 1997 |
Initial trajectory of carbon monoxide after photodissociation from myoglobin at cryogenic temperatures.
Topics: Carbon Monoxide; Crystallography, X-Ray; Freezing; Heme; Hot Temperature; Lasers; Ligands; Myoglobin; Photolysis; Protein Structure, Tertiary | 1997 |
Probing the catalytic mechanism of sulfite reductase by X-ray crystallography: structures of the Escherichia coli hemoprotein in complex with substrates, inhibitors, intermediates, and products.
Topics: Binding Sites; Carbon Monoxide; Catalysis; Crystallography, X-Ray; Cyanides; Escherichia coli; Heme; Hemeproteins; Ligands; Nitrates; Nitrites; Oxidation-Reduction; Oxidoreductases Acting on Sulfur Group Donors; Substrate Specificity; Sulfites | 1997 |
CooA, a CO-sensing transcription factor from Rhodospirillum rubrum, is a CO-binding heme protein.
Topics: Bacterial Proteins; Carbon Monoxide; Chromatography, Gel; Heme; Hemeproteins; Molecular Weight; Rhodospirillum rubrum; Spectrophotometry; Trans-Activators; Transcription Factors | 1997 |
Modification of alpha-chain or beta-chain heme pocket polarity by Val(E11) --> thr substitution has different effects on the steric, dynamic, and functional properties of human recombinant hemoglobin. Deoxy derivatives.
Topics: Carbon Monoxide; Crystallography, X-Ray; Heme; Hemoglobins; Humans; Kinetics; Point Mutation; Recombinant Proteins; Spectrum Analysis; Temperature | 1997 |
Direct observation of cooling of heme upon photodissociation of carbonmonoxy myoglobin.
Topics: Carbon Monoxide; Heme; Myoglobin; Photolysis; Photons; Spectrum Analysis, Raman; Temperature; Thermodynamics | 1997 |
Crystal structure of nitric oxide reductase from denitrifying fungus Fusarium oxysporum.
Topics: Amino Acid Sequence; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Fusarium; Heme; Iron; Models, Structural; Molecular Sequence Data; NAD; Oxidoreductases; Protein Conformation; Protein Structure, Secondary; Recombinant Proteins; Solvents | 1997 |
A comparison of functional and structural consequences of the tyrosine B10 and glutamine E7 motifs in two invertebrate hemoglobins (Ascaris suum and Lucina pectinata).
Topics: Amino Acid Substitution; Animals; Ascaris suum; Binding Sites; Bivalvia; Carbon Monoxide; Carboxyhemoglobin; Glutamic Acid; Heme; Hemoglobins; Kinetics; Oxyhemoglobins; Protein Conformation; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermodynamics; Tyrosine | 1997 |
Spontaneous spectral changes of the reduced cytochrome bd.
Topics: Azotobacter vinelandii; Bacillus subtilis; Binding Sites; Carbon Monoxide; Cytochrome b Group; Cytochromes; Dithionite; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Iron; Kinetics; Models, Chemical; Oxidation-Reduction; Oxidoreductases; Spectrophotometry | 1997 |
Pressure effects on the proximal heme pocket in myoglobin probed by Raman and near-infrared absorption spectroscopy.
Topics: Animals; Carbon Monoxide; Heme; Histidine; Horses; Iron; Ligands; Myoglobin; Pressure; Protein Conformation; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Temperature | 1997 |
The effects of heme pocket hydrophobicity on the ligand binding dynamics in myoglobin as studied with leucine 29 mutants.
Topics: Amino Acid Substitution; Binding Sites; Carbon Monoxide; Heme; Humans; Leucine; Ligands; Myoglobin; Nuclear Magnetic Resonance, Biomolecular; Photolysis; Solubility; Spectrophotometry, Infrared; Structure-Activity Relationship | 1997 |
NO synthase isozymes have distinct substrate binding sites.
Topics: Animals; Arginine; Binding Sites; Brain; Carbon Monoxide; Cattle; Cysteine; Endothelium, Vascular; Heme; Isoenzymes; Mice; Nitric Oxide Synthase; Protein Conformation; Rats; Spectrum Analysis, Raman | 1997 |
Localization of the heme binding region in soluble guanylate cyclase.
Topics: Animals; Binding Sites; Blotting, Western; Carbon Monoxide; Cattle; Dimerization; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Guanylate Cyclase; Heme; Hemeproteins; Lung; Nitric Oxide; Peptide Fragments; Protein Binding; Rats; Recombinant Proteins; Solubility; Spectrophotometry | 1997 |
Single transduction in the transcriptional activator CooA containing a heme-based CO sensor: isolation of a dominant positive mutant which is active as the transcriptional activator even in the absence of CO.
Topics: Bacterial Proteins; beta-Galactosidase; Carbon Monoxide; Escherichia coli; Gene Expression; Gene Expression Regulation, Bacterial; Genes, Reporter; Genetic Vectors; Heme; Hemeproteins; Mutagenesis; Recombinant Proteins; Rhodospirillum rubrum; Signal Transduction; Spectrophotometry; Trans-Activators; Transcriptional Activation | 1997 |
Activation of heme oxygenase and consequent carbon monoxide formation inhibits the release of arginine vasopressin from rat hypothalamic explants. Molecular linkage between heme catabolism and neuroendocrine function.
Topics: Animals; Arginine Vasopressin; Bilirubin; Biliverdine; Carbon Monoxide; Enzyme Activation; Heme; Heme Oxygenase (Decyclizing); Hemin; Hypothalamus; In Vitro Techniques; Male; Neurosecretory Systems; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Rats; Rats, Wistar | 1997 |
Mechanism of YC-1-induced activation of soluble guanylyl cyclase.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Enzyme Activation; Guanylate Cyclase; Heme; Indazoles; Kinetics; Nitrogen Oxides; Photosensitizing Agents; Platelet Aggregation Inhibitors; Protoporphyrins; Solubility | 1998 |
Probing inter-domain electron transfer in a model flavocytochrome P-450.
Topics: Bacillus megaterium; Bacterial Proteins; Carbon Monoxide; Cloning, Molecular; Cytochrome P-450 Enzyme System; Electron Transport; Escherichia coli; Flavins; Heme; Iron; Kinetics; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Recombinant Proteins | 1997 |
A possible allosteric communication pathway identified through a resonance Raman study of four beta37 mutants of human hemoglobin A.
Topics: Allosteric Regulation; Amino Acid Substitution; Carbon Monoxide; Heme; Hemoglobin A; Humans; Hydrogen Bonding; Mutation; Oxygen; Photolysis; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Recombinant Proteins; Spectrum Analysis, Raman | 1998 |
Effect of four helix bundle topology on heme binding and redox properties.
Topics: Amino Acid Sequence; Carbon Monoxide; Chromatography, Gel; Circular Dichroism; Guanidine; Heme; Hemeproteins; Iron Compounds; Ligands; Molecular Sequence Data; Oxidation-Reduction; Peptides; Protein Binding; Protein Denaturation; Protein Structure, Secondary | 1998 |
Computer simulations of carbon monoxide photodissociation in myoglobin: structural interpretation of the B states.
Topics: Animals; Biophysical Phenomena; Biophysics; Carbon Monoxide; Computer Simulation; Crystallography, X-Ray; Heme; Myoglobin; Phenylalanine; Photolysis; Point Mutation; Probability; Protein Conformation; Software; Spectrophotometry, Infrared; Static Electricity; Vibration; Whales | 1998 |
The apolar distal histidine mutant (His69-->Val) of the homodimeric Scapharca hemoglobin is in an R-like conformation.
Topics: Amino Acid Substitution; Animals; Bivalvia; Carbon Monoxide; Circular Dichroism; Dimerization; Heme; Hemoglobins; Histidine; Ligands; Mutagenesis, Insertional; Protein Binding; Protein Conformation; Spectrophotometry; Spectrum Analysis, Raman; Valine | 1998 |
Influence of proximal side mutations on the molecular and electronic structure of cyanomet myoglobin: an 1H NMR study.
Topics: Animals; Binding Sites; Carbon Monoxide; Energy Transfer; Heme; Histidine; Hydrogen-Ion Concentration; Kinetics; Ligands; Male; Metmyoglobin; Mutagenesis, Site-Directed; Nuclear Magnetic Resonance, Biomolecular; Protons; Spermatozoa; Whales | 1998 |
Coordination of nitric oxide by heme-hemopexin.
Topics: Carbon Monoxide; Circular Dichroism; Ganglia; Heme; Hemeproteins; Hemolysis; Hemopexin; Humans; Neurons; Nitric Oxide; Protein Conformation | 1998 |
Redox-coupled crystal structural changes in bovine heart cytochrome c oxidase.
Topics: Animals; Aspartic Acid; Azides; Binding Sites; Carbon Monoxide; Cattle; Copper; Crystallography, X-Ray; Electron Transport Complex IV; Heme; Hydrogen Bonding; Hydrogen Peroxide; Hydrogen-Ion Concentration; Ligands; Metals; Models, Chemical; Models, Molecular; Myocardium; Oxidation-Reduction; Oxygen; Protein Conformation; Proton Pumps; Tyrosine | 1998 |
Hypoxia-inducible factor 1alpha (HIF-1alpha) is a non-heme iron protein. Implications for oxygen sensing.
Topics: Carbon Monoxide; Cell Hypoxia; Cell Line; Deferoxamine; DNA-Binding Proteins; Helix-Loop-Helix Motifs; Heme; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Iron; Iron Chelating Agents; Luciferases; Nuclear Proteins; Oxygen; Transcription Factors | 1998 |
Detailed NMR analysis of the heme-protein interactions in component IV Glycera dibranchiata monomeric hemoglobin-CO.
Topics: Amino Acid Sequence; Animals; Carbon Monoxide; Heme; Hemeproteins; Hemoglobins; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Polychaeta; Protein Binding | 1998 |
Heme environmental structure of CooA is modulated by the target DNA binding. Evidence from resonance Raman spectroscopy and CO rebinding kinetics.
Topics: Bacterial Proteins; Carbon Monoxide; DNA; DNA-Binding Proteins; Gene Expression Regulation; Heme; Hemeproteins; Kinetics; Oligodeoxyribonucleotides; Protein Conformation; Recombinant Proteins; Rhodospirillum rubrum; Spectrum Analysis, Raman; Trans-Activators; Transcriptional Activation | 1998 |
Redox-controlled ligand exchange of the heme in the CO-sensing transcriptional activator CooA.
Topics: Bacterial Proteins; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Genes, Reporter; Heme; Hemeproteins; Lac Operon; Ligands; Mutation; Oxidation-Reduction; Recombinant Proteins; Rhodospirillum rubrum; Spectrophotometry; Trans-Activators; Transcriptional Activation | 1998 |
Heme oxygenase and nitric oxide synthase in the placenta of the guinea-pig during gestation.
Topics: Adult; Animals; Body Weight; Carbon Monoxide; Chorionic Villi; Chromatography, Gas; Female; Gestational Age; Guinea Pigs; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Immunoenzyme Techniques; Isoenzymes; Membrane Proteins; Microsomes; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Placenta; Pregnancy | 1998 |
Orientation of the heme vinyl groups in the hydrogen sulfide-binding hemoglobin I from Lucina pectinata.
Topics: Animals; Bivalvia; Carbon Monoxide; Cyanides; Heme; Hemoglobins; Hemoglobins, Abnormal; Hydrogen Sulfide; Magnetic Resonance Spectroscopy; Models, Chemical; Protons; Spectrum Analysis, Raman; Vinyl Compounds | 1998 |
Myoglobin mutants giving the largest geminate yield in CO rebinding in the nanosecond time domain.
Topics: Carbon Monoxide; Heme; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Myoglobin; Photolysis; Protein Binding; Recombinant Proteins; Spectrum Analysis, Raman | 1998 |
Structural and dynamic properties of the homodimeric hemoglobin from Scapharca inaequivalvis Thr-72-->Ile mutant: molecular dynamics simulation, low temperature visible absorption spectroscopy, and resonance Raman spectroscopy studies.
Topics: Animals; Carbon Monoxide; Dimerization; Heme; Hemoglobins; Mollusca; Mutation; Protein Binding; Spectrophotometry; Spectrum Analysis, Raman; Temperature; Water | 1998 |
Resonance raman characterization of the heme domain of soluble guanylate cyclase.
Topics: Animals; Carbon Monoxide; Ferrous Compounds; Glycine; Guanylate Cyclase; Heme; Histidine; Imidazoles; Lung; Nitric Oxide; Peptide Fragments; Protein Structure, Tertiary; Rats; Solubility; Spectrum Analysis, Raman | 1998 |
Effects of Asp-369 and Arg-372 mutations on heme environment and function in human endothelial nitric-oxide synthase.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Aspartic Acid; Carbon Monoxide; Catalytic Domain; DNA Primers; Heme; Humans; Imidazoles; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Spectrophotometry | 1998 |
The C331A mutant of neuronal nitric-oxide synthase is defective in arginine binding.
Topics: Animals; Arginine; Biopterins; Calmodulin; Carbon Monoxide; Catalytic Domain; Conserved Sequence; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Heme; Mutation; NADP; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxidation-Reduction; Rats; Recombinant Proteins; Spectrophotometry; Structure-Activity Relationship | 1998 |
Magnetic circular dichroism used to examine the interaction of Escherichia coli cytochrome bd with ligands.
Topics: Binding Sites; Carbon Monoxide; Circular Dichroism; Cyanates; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Ligands; Magnetics; Models, Chemical; Nitric Oxide; Oxidation-Reduction; Oxidoreductases; Temperature | 1999 |
Purified soluble guanylyl cyclase expressed in a baculovirus/Sf9 system: stimulation by YC-1, nitric oxide, and carbon monoxide.
Topics: Animals; Baculoviridae; Carbon Monoxide; Cell Line; Copper; Enzyme Activation; Guanylate Cyclase; Heme; Hydrazines; Indazoles; Mass Spectrometry; Nitric Oxide; Nitrogen Oxides; Recombinant Proteins; Spodoptera | 1999 |
Internal electron transfer between hemes and Cu(II) bound at cysteine beta93 promotes methemoglobin reduction by carbon monoxide.
Topics: Adult; Carbon Monoxide; Copper; Cysteine; Electron Spin Resonance Spectroscopy; Electron Transport; Heme; Humans; Kinetics; Methemoglobin; Oxidation-Reduction | 1999 |
A cyanobacterial hemoglobin with unusual ligand binding kinetics and stability properties.
Topics: Bacterial Proteins; Carbon Monoxide; Cyanobacteria; Heme; Hemin; Hemoglobins; Kinetics; Ligands; Methemoglobin; Nitric Oxide; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Protein Binding; Truncated Hemoglobins | 1999 |
Identification of two important heme site residues (cysteine 75 and histidine 77) in CooA, the CO-sensing transcription factor of Rhodospirillum rubrum.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Carbon Monoxide; Cysteine; Escherichia coli; Ferric Compounds; Ferrous Compounds; Heme; Hemeproteins; Histidine; Ligands; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Rhodospirillum rubrum; Trans-Activators | 1999 |
Characterization of the heme and pyridoxal phosphate cofactors of human cystathionine beta-synthase reveals nonequivalent active sites.
Topics: Binding Sites; Carbon Monoxide; Catalysis; Cyanides; Cystathionine beta-Synthase; Enzyme Activation; Heme; Humans; Ligands; Pyridoxal Phosphate; Recombinant Proteins; Serine; Spectrometry, Fluorescence | 1999 |
Chlamydomonas chloroplast ferrous hemoglobin. Heme pocket structure and reactions with ligands.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carbon Monoxide; Chlamydomonas; DNA Primers; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Nitric Oxide; Oxidation-Reduction; Oxygen; Protein Binding; Protein Conformation; Sequence Homology, Amino Acid; Spectrum Analysis, Raman | 1999 |
Altered ligand rebinding kinetics due to distal-side effects in hemoglobin chico (Lysbeta66(E10) --> thr).
Topics: Binding Sites; Carbon Monoxide; Globins; Heme; Hemoglobin A; Hemoglobins, Abnormal; Humans; Kinetics; Lasers; Ligands; Oxygen; Photolysis; Protein Binding; Spectrum Analysis, Raman | 1999 |
Carbon monoxide stimulates the apical 70-pS K+ channel of the rat thick ascending limb.
Topics: Animals; Biliverdine; Carbon Monoxide; Enzyme Inhibitors; Female; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase (Decyclizing); Kidney; Lysine; Male; NADP; Patch-Clamp Techniques; Porphyrins; Potassium Channels; Rats; Rats, Sprague-Dawley; RNA | 1999 |
Stoichiometric arginine binding in the oxygenase domain of inducible nitric oxide synthase requires a single molecule of tetrahydrobiopterin per dimer.
Topics: Animals; Arginine; Binding Sites; Biopterins; Carbon Monoxide; Chromatography, Gel; Conserved Sequence; Dimerization; Dithionite; Ferrous Compounds; Heme; Mice; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxygenases; Protein Binding; Recombinant Proteins; Spectrophotometry, Ultraviolet; Titrimetry | 1999 |
A steric mechanism for inhibition of CO binding to heme proteins.
Topics: Animals; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Heme; Histidine; Hydrogen Bonding; Iron; Ligands; Metmyoglobin; Models, Molecular; Myoglobin; Nitrogen; Protein Conformation; Protein Structure, Secondary; Temperature; Valine | 1999 |
Carbon monoxide and cerebral microvascular tone in newborn pigs.
Topics: Animals; Animals, Newborn; Brain; Brain Chemistry; Carbon Monoxide; Cerebral Arteries; Cerebrovascular Circulation; Chromium; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Heme; Heme Oxygenase (Decyclizing); Lysine; Mesoporphyrins; Microcirculation; Nitroarginine; Pia Mater; Potassium Channels; Swine; Tetraethylammonium; Vasodilation; Vasodilator Agents | 1999 |
Extended heme promiscuity in the cyanobacterial cytochrome c oxidase: characterization of native complexes containing hemes A, O, and D, respectively.
Topics: Acids; Blotting, Western; Carbon Monoxide; Cell Membrane; Chromatography, High Pressure Liquid; Cyanobacteria; Dithionite; Electron Transport Complex IV; Heme; Hydrogen Peroxide; Intracellular Membranes; NAD; Oxygen; Quaternary Ammonium Compounds; Spectrum Analysis; Thiosulfates | 1999 |
A study of vibrational relaxation of B-state carbon monoxide in the heme pocket of photolyzed carboxymyoglobin.
Topics: Animals; Carbon Monoxide; Computer Simulation; Heme; Histidine; Myoglobin; Static Electricity; Whales | 1999 |
Chemoreceptor discharges and cytochrome redox changes of the rat carotid body: role of heme ligands.
Topics: Afferent Pathways; Animals; Carbon Monoxide; Carotid Body; Chemoreceptor Cells; Cyanides; Cytochromes; Heme; Ligands; Oxidation-Reduction; Oxygen; Peripheral Nerves; Rats; Sulfones | 1999 |
Dynamics of the binuclear center of the quinol oxidase from Acidianus ambivalens.
Topics: Animals; Binding Sites; Carbon Monoxide; Cattle; Copper; Electron Transport; Electron Transport Complex IV; Heme; Kinetics; Oxidation-Reduction; Oxidoreductases; Photolysis; Sulfolobales; Temperature; Thermodynamics | 1999 |
Carbon monoxide as a novel mediator of the febrile response in the central nervous system.
Topics: Animals; Body Temperature; Carbon Monoxide; Central Nervous System; Deuteroporphyrins; Enzyme Inhibitors; Fever; Heme; Heme Oxygenase (Decyclizing); Injections, Intraperitoneal; Injections, Intraventricular; Lipopolysaccharides; Lysine; Male; Rats; Rats, Wistar; Reference Values; Sodium Chloride; Time Factors | 1999 |
The G464S amino acid substitution in Candida albicans sterol 14alpha-demethylase causes fluconazole resistance in the clinic through reduced affinity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Antifungal Agents; Candida albicans; Carbon Monoxide; Catalysis; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Microbial; Ergosterol; Fluconazole; Heme; Inhibitory Concentration 50; Kinetics; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Protein Binding; Saccharomyces cerevisiae; Spectrum Analysis; Sterol 14-Demethylase | 1999 |
Coherent reaction dynamics in a bacterial cytochrome c oxidase.
Topics: Carbon Monoxide; Electron Transport Complex IV; Heme; Kinetics; Ligands; Oxygen; Paracoccus denitrificans; Water | 1999 |
Probing the heme axial ligation in the CO-sensing CooA protein with magnetic circular dichroism spectroscopy.
Topics: Bacterial Proteins; Carbon Monoxide; Circular Dichroism; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Fimbriae Proteins; Heme; Magnetics; Molecular Probes | 1999 |
Reversal of HO-1 related cytoprotection with increased expression is due to reactive iron.
Topics: Animals; Bilirubin; Carbon Monoxide; Cricetinae; Doxycycline; Gene Expression; Glutathione; Guanosine Monophosphate; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Iron; Oxidative Stress; Oxygen; Recombinant Proteins; Thiobarbituric Acid Reactive Substances | 1999 |
Magnesium(II) and zinc(II)-protoporphyrin IX's stabilize the lowest oxygen affinity state of human hemoglobin even more strongly than deoxyheme.
Topics: Allosteric Regulation; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Models, Molecular; Mutation; Oxygen; Phytic Acid; Protein Structure, Quaternary; Protein Structure, Tertiary; Protons; Protoporphyrins; Spectrophotometry; Thermodynamics | 1999 |
Crystal structures of myoglobin-ligand complexes at near-atomic resolution.
Topics: Animals; Anisotropy; Binding Sites; Carbon Monoxide; Crystallization; Crystallography, X-Ray; Electrons; Heme; Histidine; Hydrogen Bonding; Ligands; Metmyoglobin; Models, Molecular; Myoglobin; Oxygen; Protein Conformation; Protons; Water; Whales | 1999 |
Resonance Raman studies of cytochrome P450BM3 and its complexes with exogenous ligands.
Topics: Bacillus megaterium; Bacterial Proteins; Camphor 5-Monooxygenase; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ferric Compounds; Ferrous Compounds; Heme; Holoenzymes; Ligands; Macromolecular Substances; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Nitric Oxide; Protein Structure, Tertiary; Spectrum Analysis, Raman; Substrate Specificity | 1999 |
Recombinant hemoglobin(alpha 29leucine --> phenylalanine, alpha 96valine --> tryptophan, beta 108asparagine --> lysine) exhibits low oxygen affinity and high cooperativity combined with resistance to autoxidation.
Topics: Amino Acid Substitution; Asparagine; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Heme; Hemoglobins; Humans; Kinetics; Leucine; Lysine; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Phenylalanine; Protein Binding; Recombinant Proteins; Tryptophan; Valine | 1999 |
A cytochrome bb'-type quinol oxidase in Bacillus subtilis strain 168.
Topics: Bacillus subtilis; Carbon Monoxide; Cell Respiration; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Electron Transport Complex IV; Enzyme Inhibitors; Escherichia coli Proteins; Genes, Bacterial; Glucose; Heme; Membrane Proteins; Multienzyme Complexes; Mutation; NADH, NADPH Oxidoreductases; Oxidoreductases; Protons; Quinolones; Sodium Cyanide; Spectrophotometry | 1999 |
Activation of soluble guanylate cyclase by carbon monoxide and nitric oxide: a mechanistic model.
Topics: Carbon Monoxide; Enzyme Activation; Guanylate Cyclase; Heme; Kinetics; Models, Chemical; Models, Theoretical; Myoglobin; Nitric Oxide; Solubility; Spectrum Analysis; Thermodynamics | 1999 |
The peroxynitrite reductase activity of cytochrome c oxidase involves a two-electron redox reaction at the heme a(3)-Cu(B) site.
Topics: Animals; Carbon Monoxide; Cattle; Copper; Electron Transport; Electron Transport Complex IV; Heme; Kinetics; Mitochondria, Heart; Nitrates; Oxidants; Oxidation-Reduction; Oxidoreductases; Spectrophotometry | 1999 |
Vibrational population relaxation of carbon monoxide in the heme pocket of photolyzed carbonmonoxy myoglobin: comparison of time-resolved mid-IR absorbance experiments and molecular dynamics simulations.
Topics: Carbon Monoxide; Heme; Myoglobin; Photolysis; Spectrophotometry, Infrared; Vibration | 1999 |
Spectroscopic characterization of the heme-binding sites in Plasmodium falciparum histidine-rich protein 2.
Topics: Animals; Binding Sites; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Heme; Histidine; Plasmodium falciparum; Proteins; Protozoan Proteins; Spectrophotometry; Spectrum Analysis, Raman | 1999 |
Harmonic and anharmonic dynamics of Fe-CO and Fe-O(2) in heme models.
Topics: Carbon Monoxide; Computer Simulation; Heme; Iron; Models, Chemical; Oxygen; Porphyrins | 2000 |
A cooperative oxygen binding hemoglobin from Mycobacterium tuberculosis. Stabilization of heme ligands by a distal tyrosine residue.
Topics: Carbon Monoxide; Heme; Hemoglobins; Hydrogen; Hydroxides; Ligands; Models, Chemical; Mycobacterium tuberculosis; Oxygen; Recombinant Proteins; Spectrum Analysis, Raman; Tyrosine | 2000 |
Femtosecond resolution of ligand-heme interactions in the high-affinity quinol oxidase bd: A di-heme active site?
Topics: Binding Sites; Carbon Monoxide; Cytochrome a Group; Cytochrome b Group; Cytochromes; Cytochromes a1; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Kinetics; Ligands; Oxidation-Reduction; Oxidoreductases; Spectrophotometry | 2000 |
Dos, a heme-binding PAS protein from Escherichia coli, is a direct oxygen sensor.
Topics: Amino Acid Sequence; Bacterial Proteins; Carbon Monoxide; Carrier Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Heme-Binding Proteins; Hemeproteins; Histidine Kinase; Molecular Sequence Data; Multigene Family; Nitric Oxide; Oxygen; Polymers; Protein Structure, Tertiary; Spectrophotometry; Type III Secretion Systems | 2000 |
Identification of the proximal ligand His-20 in heme oxygenase (Hmu O) from Corynebacterium diphtheriae. Oxidative cleavage of the heme macrocycle does not require the proximal histidine.
Topics: Bacterial Proteins; Biliverdine; Carbon Monoxide; Catalytic Domain; Chromatography, High Pressure Liquid; Corynebacterium diphtheriae; Electrophoresis, Polyacrylamide Gel; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Histidine; Humans; Hydroxylation; Ligands; Membrane Proteins; Models, Chemical; Mutagenesis, Site-Directed; Oxidation-Reduction; Spectrophotometry, Atomic; Spectrum Analysis, Raman; Structure-Activity Relationship | 2000 |
Central CO-heme oxygenase pathway raises body temperature by a prostaglandin-independent way.
Topics: Animals; Body Temperature; Carbon Monoxide; Central Nervous System; Cyclooxygenase Inhibitors; Deuteroporphyrins; Dinoprostone; Enzyme Inhibitors; Fever; Heme; Heme Oxygenase (Decyclizing); Indomethacin; Injections, Intraperitoneal; Injections, Intraventricular; Lipopolysaccharides; Lysine; Male; Prostaglandins; Rats; Rats, Wistar; Time Factors | 2000 |
Flexibility and stability of the structure of cytochromes P450 3A4 and BM-3.
Topics: Bacterial Proteins; Binding Sites; Carbon Monoxide; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Enzyme Stability; Escherichia coli; Heme; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Plasmids; Pliability; Pressure; Protein Binding; Protein Conformation; Spectrophotometry; Temperature; Troleandomycin | 2000 |
Coupling of electron transfer with proton transfer at heme a and Cu(A) (redox Bohr effects) in cytochrome c oxidase. Studies with the carbon monoxide inhibited enzyme.
Topics: Animals; Carbon Monoxide; Cattle; Electron Transport; Electron Transport Complex IV; Heme; Hydrogen-Ion Concentration; Kinetics; Mitochondria, Heart; Models, Chemical; Oxidation-Reduction; Protons | 2000 |
Resonance raman studies of oxo intermediates in the reaction of pulsed cytochrome bo with hydrogen peroxide.
Topics: Bacterial Proteins; Carbon Monoxide; Cytochrome b Group; Cytochromes; Deuterium Oxide; Escherichia coli; Escherichia coli Proteins; Free Radicals; Heme; Hydrogen Peroxide; Hydrogen-Ion Concentration; Iron; Oxygen Isotopes; Spectrum Analysis, Raman; Tyrosine | 2000 |
Unique heme environment at the putative distal region of hydrogen peroxide-dependent fatty acid alpha-hydroxylase from Sphingomonas paucimobilis (peroxygenase P450(SPalpha).
Topics: Amines; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Fatty Acids; Heme; Imidazoles; Iron; Ligands; Mixed Function Oxygenases; Peroxidases; Pyridines; Sodium Cyanide; Spectrophotometry; Sphingomonas | 2000 |
Dissociation and recombination between ligands and heme in a CO-sensing transcriptional activator CooA. A flash photolysis study.
Topics: Bacterial Proteins; Carbon Monoxide; Heme; Hemeproteins; Kinetics; Ligands; Oxidation-Reduction; Photolysis; Rhodospirillum rubrum; Spectrophotometry; Time Factors; Trans-Activators | 2000 |
Proton-coupled structural changes upon binding of carbon monoxide to cytochrome cd1: a combined flash photolysis and X-ray crystallography study.
Topics: Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Cytochrome c Group; Cytochromes; Electron Transport; Heme; Kinetics; Ligands; Models, Molecular; Nitrite Reductases; Oxidation-Reduction; Paracoccus; Photolysis; Protons; Solutions | 2000 |
Resonance Raman studies indicate a unique heme active site in prostaglandin H synthase.
Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Ferric Compounds; Ferrous Compounds; Heme; Hydrogen-Ion Concentration; Iron; Ligands; Male; Prostaglandin-Endoperoxide Synthases; Protein Binding; Protein Conformation; Sheep; Spectrum Analysis, Raman | 2000 |
Identification of histidine 77 as the axial heme ligand of carbonmonoxy CooA by picosecond time-resolved resonance Raman spectroscopy.
Topics: Bacterial Proteins; Carbon Monoxide; Escherichia coli; Escherichia coli Proteins; Fimbriae Proteins; Heme; Histidine; Imidazoles; Iron; Ligands; Mutagenesis, Site-Directed; Myoglobin; Photolysis; Spectrum Analysis, Raman; Tyrosine | 2000 |
Functional properties of the active core of human cystathionine beta-synthase crystals.
Topics: Binding Sites; Carbon Monoxide; Cystathionine beta-Synthase; Heme; Homocysteine; Humans; Microspectrophotometry; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Pyridoxal Phosphate; Recombinant Proteins; Serine; Structure-Activity Relationship | 2001 |
Autocatalytic nitration of P450CAM by peroxynitrite.
Topics: Binding Sites; Blotting, Western; Camphor 5-Monooxygenase; Carbon Monoxide; Catalysis; Cytochrome P-450 Enzyme System; Heme; Hydroxylation; Intramolecular Oxidoreductases; Kinetics; Ligands; Mass Spectrometry; Models, Molecular; Nitrates; Nitrogen; Phenol; Protein Binding; Protein Conformation; Protons; Spectrophotometry; Time Factors; Tyrosine | 2000 |
Unprecedented proximal binding of nitric oxide to heme: implications for guanylate cyclase.
Topics: Alcaligenes; Bacterial Proteins; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Cytochrome c Group; Guanylate Cyclase; Heme; Hemeproteins; Models, Molecular; Nitric Oxide; Oxidation-Reduction; Protein Conformation; Static Electricity; Trans-Activators | 2000 |
Roles of Ile209 and Ile210 on the heme pocket structure and regulation of histidine kinase activity of oxygen sensor FixL from Rhizobium meliloti.
Topics: Bacterial Proteins; Carbon Monoxide; Enzyme Activation; Ferric Compounds; Heme; Hemeproteins; Histidine; Histidine Kinase; Isoleucine; Mutagenesis, Site-Directed; Oxygen; Phosphorylation; Protein Binding; Protein Conformation; Protein Kinases; Sinorhizobium meliloti; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Tryptophan | 2000 |
Formation of the "peroxy" intermediate in cytochrome c oxidase is associated with internal proton/hydrogen transfer.
Topics: Carbon Monoxide; Electron Transport; Electron Transport Complex IV; Entropy; Ferrous Compounds; Heme; Kinetics; Oxidation-Reduction; Oxygen; Photolysis; Protons; Rhodobacter sphaeroides; Solutions | 2000 |
Heme oxygenase activity in term human placenta.
Topics: Amnion; Carbon Monoxide; Chorion; Chorionic Villi; Decidua; Female; Heme; Heme Oxygenase (Decyclizing); Humans; Microsomes; NADP; Placenta; Pregnancy | 2000 |
Resonance Raman characterization of the heme cofactor in cystathionine beta-synthase. Identification of the Fe-S(Cys) vibration in the six-coordinate low-spin heme.
Topics: Binding, Competitive; Carbon Monoxide; Cystathionine beta-Synthase; Cysteine; Ferric Compounds; Ferrous Compounds; Heme; Homocysteine; Humans; Iron-Sulfur Proteins; Ligands; Mercuric Chloride; Molybdenum; Oxidation-Reduction; Protein Binding; Pyridoxal Phosphate; Spectrum Analysis, Raman | 2001 |
Contributions of prostacyclin and nitric oxide to carbon monoxide-induced cerebrovascular dilation in piglets.
Topics: Animals; Animals, Newborn; Arterioles; Carbon Monoxide; Heme; Indomethacin; Kinetics; Lysine; Microcirculation; Muscle, Smooth, Vascular; Nitric Oxide; Nitroarginine; Peptides; Pia Mater; Potassium Channels; Scorpion Venoms; Swine; Tetraethylammonium; Vasodilation; Vasodilator Agents | 2001 |
Retention of heme in axial ligand mutants of succinate-ubiquinone xxidoreductase (complex II) from Escherichia coli.
Topics: Benzoquinones; Binding Sites; Carbon Monoxide; Cell Membrane; Electron Spin Resonance Spectroscopy; Electron Transport Complex II; Enzyme Inhibitors; Escherichia coli; Heme; Hydrogen-Ion Concentration; Indicators and Reagents; Kinetics; Ligands; Light; Multienzyme Complexes; Mutation; Oxidation-Reduction; Oxidoreductases; Pentachlorophenol; Plasmids; Protein Binding; Protein Structure, Tertiary; Spectrophotometry; Succinate Dehydrogenase; Time Factors; Uncoupling Agents | 2001 |
Carbon monoxide from heme catabolism protects against hepatobiliary dysfunction in endotoxin-treated rat liver.
Topics: Animals; Bile; Carbon Monoxide; Chemical and Drug Induced Liver Injury; Cholestasis; Cytochrome P-450 Enzyme System; Endotoxemia; Heme; Kupffer Cells; Lipopolysaccharides; Liver; Liver Diseases; Male; Methemoglobin; Nitric Oxide; Oxyhemoglobins; Rats; Rats, Wistar; Shock; Stress, Physiological; Transfusion Reaction; Vasoconstriction; Vasodilation | 2001 |
The heme-regulated eukaryotic initiation factor 2alpha kinase. A potential regulatory target for control of protein synthesis by diffusible gases.
Topics: Animals; Carbon Monoxide; eIF-2 Kinase; Heme; Humans; Nitric Oxide; Phosphorylation; Recombinant Proteins | 2001 |
Interaction of cytochrome bd with carbon monoxide at low and room temperatures: evidence that only a small fraction of heme b595 reacts with CO.
Topics: Carbon Monoxide; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Escherichia coli Proteins; Heme; Oxidoreductases; Temperature | 2001 |
Structural and dynamic perturbations induced by heme binding in cytochrome b5.
Topics: Alanine; Amino Acid Substitution; Animals; Apoproteins; Carbon Monoxide; Crystallography, X-Ray; Cytochrome b Group; Cytochromes b; Cytochromes b5; Heme; Histidine; Macromolecular Substances; Methylamines; Nuclear Magnetic Resonance, Biomolecular; Oxidants; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Denaturation; Protein Folding; Rats; Thermodynamics | 2001 |
Phosphodiesterase A1, a regulator of cellulose synthesis in Acetobacter xylinum, is a heme-based sensor.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Carbon Monoxide; Cellulose; Escherichia coli Proteins; Gluconacetobacter xylinus; Heme; Molecular Sequence Data; Oxygen; Phospholipases A; Protein Structure, Tertiary; Spectrophotometry; Type III Secretion Systems | 2001 |
Resonance Raman studies of cytochrome c' support the binding of NO and CO to opposite sides of the heme: implications for ligand discrimination in heme-based sensors.
Topics: Alcaligenes; Bacterial Proteins; Binding Sites; Carbon Monoxide; Cytochrome c Group; Ferrous Compounds; Guanylate Cyclase; Heme; Hemeproteins; Ligands; Nitric Oxide; Solutions; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Trans-Activators | 2001 |
A photolysis-triggered heme ligand switch in H93G myoglobin.
Topics: Animals; Carbon Monoxide; Ferrous Compounds; Glycine; Heme; Histidine; Iron; Lasers; Ligands; Metmyoglobin; Mutagenesis, Insertional; Myoglobin; Photolysis; Protein Binding; Spectrum Analysis, Raman; Thermodynamics; Whales | 2001 |
Taenia crassiceps metacestodes have cytochrome oxidase aa3 but not cytochrome o functioning as terminal oxidase.
Topics: Animals; Calorimetry; Carbon Monoxide; Cytochrome b Group; Cytochromes; Electron Transport Complex IV; Escherichia coli Proteins; Heme; Kinetics; Larva; Mitochondria; Spectrophotometry; Taenia | 2001 |
The kinetic and spectral characterization of the E. coli-expressed mammalian CYP4A7: cytochrome b5 effects vary with substrate.
Topics: Animals; Apoproteins; Binding Sites; Carbon Monoxide; COS Cells; Cytochrome b Group; Cytochrome P-450 CYP4A; Cytochrome P-450 Enzyme System; Cytochromes b; Cytochromes b5; Escherichia coli; Fatty Acids; Flavins; Heme; Hydroxylation; Kidney; Kinetics; Mixed Function Oxygenases; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Binding; Rabbits; Rats; Recombinant Proteins; Spectrum Analysis; Substrate Specificity; Transfection | 2001 |
Very high resolution structure of a trematode hemoglobin displaying a TyrB10-TyrE7 heme distal residue pair and high oxygen affinity.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Heme; Hydrogen Bonding; Iron; Kinetics; Ligands; Methemoglobin; Models, Molecular; Molecular Sequence Data; Oxygen; Paramphistomatidae; Protein Structure, Quaternary; Protein Structure, Secondary; Sequence Alignment; Thermodynamics; Tyrosine | 2001 |
Carbon monoxide adducts of KatG and KatG(S315T) as probes of the heme site and isoniazid binding.
Topics: Amino Acid Substitution; Antitubercular Agents; Bacterial Proteins; Binding Sites; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Ferric Compounds; Heme; Isoniazid; Mycobacterium tuberculosis; Peroxidases; Serine; Spectrum Analysis, Raman; Threonine | 2001 |
Spectral studies of tert-butyl isothiocyanate-inactivated P450 2E1.
Topics: Animals; Binding Sites; Carbon Monoxide; Chromatography, Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dithionite; Electron Spin Resonance Spectroscopy; Enzyme Activation; Enzyme Inhibitors; Fomepizole; Heme; Iodobenzenes; Isothiocyanates; NADP; Pyrazoles; Rabbits; Rats; Spectrometry, Mass, Electrospray Ionization | 2001 |
Vasoregulatory function of the heme-heme oxygenase-carbon monoxide system.
Topics: Animals; Blood Pressure; Blood Vessels; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing) | 2001 |
Influence of the heme pocket conformation on the structure and vibrations of the Fe-CO bond in myoglobin: a QM/MM density functional study.
Topics: Carbon Monoxide; Computer Simulation; Heme; Histidine; Iron; Ligands; Models, Molecular; Myoglobin; Protein Conformation; Thermodynamics; Vibration | 2001 |
Site-directed mutation of the highly conserved region near the Q-loop of the cytochrome bd quinol oxidase from Escherichia coli specifically perturbs heme b595.
Topics: Alanine; Amino Acid Sequence; Carbon Monoxide; Conserved Sequence; Cyanides; Cytochrome b Group; Cytochromes; Electrochemistry; Electron Spin Resonance Spectroscopy; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Glutamic Acid; Heme; Molecular Sequence Data; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxidoreductases; Oxidoreductases, N-Demethylating; Protein Binding; Protein Structure, Tertiary; Quinone Reductases; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2001 |
Presence of the heme-oxo intermediate in oxygenation of carbon monoxide by cytochrome c oxidase revealed by resonance Raman spectroscopy.
Topics: Animals; Carbon Dioxide; Carbon Monoxide; Cattle; Electron Transport Complex IV; Heme; Oxidation-Reduction; Spectrum Analysis, Raman | 2001 |
The heme environment of mouse neuroglobin. Evidence for the presence of two conformations of the heme pocket.
Topics: Animals; Carbon Monoxide; Globins; Heme; Hydrogen-Ion Concentration; Iron; Kinetics; Ligands; Mice; Nerve Tissue Proteins; Neuroglobin; Oxygen; Protein Binding; Protein Conformation; Recombinant Proteins; Spectrum Analysis, Raman | 2001 |
Kinetics of CO binding to the haem domain of murine inducible nitric oxide synthase: differential effects of haem domain ligands.
Topics: Animals; Arginine; Carbon Monoxide; Cloning, Molecular; Escherichia coli; Heme; Kinetics; Ligands; Light; Mice; Models, Chemical; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Photolysis; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; Recombination, Genetic; Spectrophotometry; Time Factors | 2001 |
Cationic ascorbate peroxidase isoenzyme II from tea: structural insights into the heme pocket of a unique hybrid peroxidase.
Topics: Ascorbate Peroxidases; Binding Sites; Carbon Monoxide; Cyanides; Ferric Compounds; Ferrous Compounds; Fluorides; Heme; Hydrogen Bonding; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Peroxidases; Plant Leaves; Quantum Theory; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Tea | 2001 |
Oligomerization and ligand binding in a homotetrameric hemoglobin: two high-resolution crystal structures of hemoglobin Bart's (gamma(4)), a marker for alpha-thalassemia.
Topics: alpha-Thalassemia; Azides; Carbon Monoxide; Crystallography, X-Ray; Heme; Hemoglobins, Abnormal; Humans; Ligands; Metals; Models, Molecular; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Protein Subunits; Static Electricity; Stereoisomerism | 2001 |
Interrogation of heme pocket environment of mammalian peroxidases with diatomic ligands.
Topics: Anaerobiosis; Animals; Binding Sites; Carbon Monoxide; Ferric Compounds; Ferrous Compounds; Heme; Kinetics; Ligands; Mammals; Nitric Oxide; Oxidants; Peroxidase; Spectrophotometry; Swine | 2001 |
Binding of NO and CO to the d(1) Heme of cd(1) nitrite reductase from Pseudomonas aeruginosa.
Topics: Carbon Monoxide; Cytochromes; Electron Transport Complex IV; Heme; Models, Molecular; Molecular Conformation; Nitric Oxide; Nitrite Reductases; Pseudomonas aeruginosa; Spectrophotometry; Spectrum Analysis, Raman | 2001 |
The heme pocket afforded by Gly117 is crucial for proper heme ligation and activity of CooA.
Topics: Bacterial Proteins; Carbon Monoxide; DNA; Glycine; Heme; Hemeproteins; Hydrogen-Ion Concentration; Ligands; Trans-Activators | 2001 |
Quantitative analysis of x-ray absorption near edge structure data by a full multiple scattering procedure: the Fe-CO geometry in photolyzed carbonmonoxy-myoglobin single crystal.
Topics: Animals; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Heme; Iron; Myoglobin; Photolysis; Protein Conformation; Scattering, Radiation; Spectrometry, X-Ray Emission; Whales | 2001 |
Conformational dynamics of the transcriptional regulator CooA protein studied by subpicosecond mid-infrared vibrational spectroscopy.
Topics: Bacterial Proteins; Carbon Monoxide; Heme; Hemeproteins; Hemoglobins; Kinetics; Myoglobin; Protein Conformation; Spectrophotometry, Infrared; Trans-Activators | 2001 |
Regulation of human heme oxygenase in endothelial cells by using sense and antisense retroviral constructs.
Topics: 3T3 Cells; Animals; Carbon Monoxide; Cells, Cultured; Culture Media; Endothelium, Vascular; Gene Expression; Genetic Vectors; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Membrane Proteins; Mice; Oligonucleotides, Antisense; Rats; Retroviridae; RNA, Messenger | 2001 |
Insights into the signal transduction mechanism of RmFixL provided by carbon monoxide recombination kinetics.
Topics: Bacterial Proteins; Carbon Monoxide; Chromatography; Chromatography, High Pressure Liquid; Dimerization; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Heme; Hemeproteins; Histidine Kinase; Kinetics; Ligands; Light; Models, Chemical; Oxygen; Photolysis; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Temperature; Time Factors | 2001 |
Reaction of carbon monoxide with the reduced active site of bacterial nitric oxide reductase.
Topics: Binding Sites; Carbon Monoxide; Cell Division; Circular Dichroism; Copper; Electron Spin Resonance Spectroscopy; Electron Transport; Electrons; Heme; Iron; Kinetics; Ligands; Oxidation-Reduction; Oxidoreductases; Paracoccus denitrificans; Photolysis; Spectrophotometry | 2001 |
Phenylalanine 393 exerts thermodynamic control over the heme of flavocytochrome P450 BM3.
Topics: Amino Acid Sequence; Bacterial Proteins; Carbon Monoxide; Cytochrome P-450 Enzyme System; Escherichia coli; Fatty Acids; Heme; Iron; Kinetics; Mixed Function Oxygenases; Molecular Sequence Data; Mutation; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxygen; Phenylalanine; Potentiometry; Sequence Homology, Amino Acid; Sulfur; Thermodynamics; Titrimetry | 2001 |
Protein conformational relaxation and ligand migration in myoglobin: a nanosecond to millisecond molecular movie from time-resolved Laue X-ray diffraction.
Topics: Animals; Carbon Monoxide; Computer Simulation; Crystallography, X-Ray; Fourier Analysis; Half-Life; Heme; Ligands; Models, Molecular; Myoglobin; Photolysis; Protein Binding; Protein Conformation; Thermodynamics; Time Factors; Whales | 2001 |
Adrenodoxin-cytochrome P450scc interaction as revealed by EPR spectroscopy: comparison with the putidaredoxin-cytochrome P450cam system.
Topics: Adrenal Cortex; Adrenodoxin; Amino Acid Sequence; Animals; Camphor 5-Monooxygenase; Carbon Monoxide; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Electron Spin Resonance Spectroscopy; Ferredoxins; Heme; Iron; Models, Molecular; Molecular Sequence Data; Nitric Oxide; Oxidation-Reduction; Oxygen; Pseudomonas putida; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2001 |
Effect of a charge relay on the vibrational frequencies of carbonmonoxy iron porphine adducts: the coupling of changes in axial ligand bond strength and porphine core size.
Topics: Carbon Monoxide; Heme; Hydrogen Bonding; Imidazoles; Iron; Metalloporphyrins; Models, Chemical; Models, Molecular; Peroxidase; Static Electricity; Vibration | 2001 |
Characterization of NO binding to human cystathionine beta-synthase: possible implications of the effects of CO and NO binding to the human enzyme.
Topics: Carbon Monoxide; Cystathionine beta-Synthase; Electron Spin Resonance Spectroscopy; Escherichia coli; Heme; Humans; Kinetics; Models, Chemical; Nitric Oxide; Spectrophotometry | 2001 |
Role of CO in attenuated vasoconstrictor reactivity of mesenteric resistance arteries after chronic hypoxia.
Topics: Animals; Blood Pressure; Carbon Monoxide; Heme; Hypoxia; Lysine; Male; Mesenteric Arteries; Nitric Oxide; Nitroarginine; Phenylephrine; Rats; Rats, Sprague-Dawley; Reference Values; Vascular Resistance; Vasoconstriction; Vasodilator Agents | 2002 |
Interactions between heme d and heme b595 in quinol oxidase bd from Escherichia coli: a photoselection study using femtosecond spectroscopy.
Topics: Alanine; Amino Acid Substitution; Animals; Binding Sites; Carbon Monoxide; Cell Membrane; Escherichia coli; Glutamic Acid; Heme; Mutagenesis, Site-Directed; Myoglobin; Oxidation-Reduction; Oxidoreductases; Oxygen; Photolysis; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet | 2002 |
Role of the preoptic carbon monoxide pathway in endotoxin fever in rats.
Topics: Animals; Carbon Monoxide; Cyclic GMP; Deuteroporphyrins; Endotoxemia; Enzyme Inhibitors; Fever; Heme; Heme Oxygenase (Decyclizing); Injections, Intraventricular; Lipopolysaccharides; Lysine; Male; Methylene Blue; Microinjections; Preoptic Area; Rats; Rats, Wistar; Vasodilator Agents | 2002 |
The leghemoglobin proximal heme pocket directs oxygen dissociation and stabilizes bound heme.
Topics: Animals; Carbon Monoxide; Heme; Iron; Kinetics; Leghemoglobin; Ligands; Models, Molecular; Mutation; Myoglobin; Oxygen; Whales | 2002 |
Proton and electron pathways in the bacterial nitric oxide reductase.
Topics: Bacterial Proteins; Binding Sites; Carbon Monoxide; Electron Transport; Heme; Lasers; Nitric Oxide; Oxidation-Reduction; Oxidoreductases; Paracoccus denitrificans; Photolysis; Protons; Spectrophotometry | 2002 |
A comparative resonance Raman analysis of heme-binding PAS domains: heme iron coordination structures of the BjFixL, AxPDEA1, EcDos, and MtDos proteins.
Topics: Acetobacter; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Bradyrhizobium; Carbon Monoxide; Escherichia coli; Euryarchaeota; Heme; Hemeproteins; Histidine Kinase; Molecular Sequence Data; Protein Conformation; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Spectrum Analysis, Raman | 2002 |
An archaeal b-type cytochrome containing a nonfunctional carbonic anhydrase-like domain.
Topics: Amino Acid Sequence; Archaeal Proteins; Carbon Monoxide; Carbonic Anhydrases; Crenarchaeota; Cytochrome b Group; Heme; Hydrogen-Ion Concentration; Molecular Sequence Data; Protein Structure, Tertiary; Sequence Analysis, Protein; Sequence Homology, Amino Acid; Solubility; Zinc | 2002 |
Decay of the transient Cu(B)-CO complex is accompanied by formation of the heme Fe-CO complex of cytochrome cbb(3)-CO at ambient temperature: evidence from time-resolved Fourier transform infrared spectroscopy.
Topics: Carbon Monoxide; Electron Transport Complex IV; Heme; Iron; Spectroscopy, Fourier Transform Infrared | 2002 |
Functional expression of human heme oxygenase-1 (HO-1) driven by HO-1 promoter in vitro and in vivo.
Topics: Animals; Animals, Newborn; Blotting, Western; Carbon Monoxide; Cells, Cultured; Cyclic GMP; Dinoprostone; Endothelium, Vascular; Gene Expression; Gene Expression Regulation, Enzymologic; Genetic Vectors; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Lung; Membrane Proteins; Mice; Polymerase Chain Reaction; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Retroviridae; RNA, Messenger | 2002 |
Biomimetic studies of terminal oxidases: trisimidazole picket metalloporphyrins.
Topics: Amines; Binding Sites; Carbon Monoxide; Catalysis; Copper; Electron Spin Resonance Spectroscopy; Heme; Imidazoles; Iron; Magnetic Resonance Spectroscopy; Metalloporphyrins; Models, Molecular; Molecular Conformation; Molecular Mimicry; Nitrogen; Oxidoreductases; Spectrophotometry, Infrared; Zinc | 2002 |
Cerebrovasodilatory contribution of endogenous carbon monoxide during seizures in newborn pigs.
Topics: Animals; Animals, Newborn; Arterioles; Bicuculline; Carbon Monoxide; Cerebral Arteries; Cerebrovascular Circulation; Convulsants; Cyclic AMP; Cyclic GMP; Enzyme Inhibitors; GABA Antagonists; Glutamates; Heme; Heme Oxygenase (Decyclizing); Membrane Potentials; Mesoporphyrins; Metalloporphyrins; Nerve Tissue Proteins; Neurons; Pia Mater; Protoporphyrins; Seizures; Status Epilepticus; Swine; Vasodilation | 2002 |
Heme oxygenase activity in placenta: direct dependence on oxygen availability.
Topics: Carbon Monoxide; Chorionic Villi; Female; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Hypoxia; Membrane Proteins; Microsomes; Oxygen; Placenta; Pre-Eclampsia; Pregnancy; Regression Analysis; RNA, Messenger | 2002 |
The carbon monoxide derivative of human hemoglobin carrying the double mutation LeuB10-->Tyr and HisE7-->Gln on alpha and beta chains probed by infrared spectroscopy.
Topics: Amino Acid Substitution; Carbon Monoxide; Carboxyhemoglobin; Glutamine; Heme; Hemoglobin A; Histidine; Humans; Hydrogen Bonding; Iron; Kinetics; Leucine; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Tyrosine | 2002 |
Stationary and time-resolved resonance Raman spectra of His77 and Met95 mutants of the isolated heme domain of a direct oxygen sensor from Escherichia coli.
Topics: Carbon Monoxide; Carrier Proteins; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Heme; Histidine; Hydrogen-Ion Concentration; Ligands; Methionine; Mutation; Oxygen; Phosphoric Diester Hydrolases; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Spectrum Analysis, Raman; Time Factors | 2002 |
Why should heme be degraded to iron, bile pigments, and carbon monoxide?
Topics: Bile Acids and Salts; Biological Transport; Carbon Monoxide; Heme; Hemoglobins; Humans; Iron; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases | 2002 |
Contribution of heme-propionate side chains to structure and function of myoglobin: chemical approach by artificially created prosthetic groups.
Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Heme; Horses; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Myocardium; Myoglobin; Oxidation-Reduction; Oxygen; Protein Binding; Protein Structure, Tertiary | 2002 |
Analysis of the L116K variant of CooA, the heme-containing CO sensor, suggests the presence of an unusual heme ligand resulting in novel activity.
Topics: Bacterial Proteins; Carbon Monoxide; DNA; Heme; Hemeproteins; Iron; Ligands; Protein Conformation; Rhodospirillum rubrum; Trans-Activators | 2002 |
The rate of internal heme-heme electron transfer in cytochrome C oxidase.
Topics: Animals; Carbon Monoxide; Cattle; Electron Transport; Electron Transport Complex IV; Heme; Kinetics; Oxidation-Reduction; Photolysis; Spectrophotometry | 2002 |
Alleviation of intrasteric inhibition by the pathogenic activation domain mutation, D444N, in human cystathionine beta-synthase.
Topics: Allosteric Regulation; Amino Acid Substitution; Asparagine; Aspartic Acid; Carbon Monoxide; Cell Line; Cystathionine beta-Synthase; Enzyme Activation; Ferrous Compounds; Fibroblasts; Heme; Humans; Kinetics; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Recombinant Proteins; RNA, Messenger; S-Adenosylmethionine | 2002 |
Ultrafast ligand rebinding in the heme domain of the oxygen sensors FixL and Dos: general regulatory implications for heme-based sensors.
Topics: Bacterial Proteins; Bradyrhizobium; Carbon Monoxide; DNA; Drosophila Proteins; Escherichia coli; Eye Proteins; Heme; Hemeproteins; Histidine Kinase; Kinetics; Ligands; Models, Biological; Myoglobin; Nitric Oxide; Oxygen; Protein Binding; Protein Structure, Tertiary; Signal Transduction; Spectrophotometry; Time Factors | 2002 |
Carbon monoxide dilates cerebral arterioles by enhancing the coupling of Ca2+ sparks to Ca2+-activated K+ channels.
Topics: Animals; Arterioles; Calcium Channel Blockers; Calcium Signaling; Carbon Monoxide; Cells, Cultured; Cerebral Arteries; Culture Techniques; Electric Conductivity; Heme; Kinetics; Lysine; Muscle, Smooth, Vascular; Potassium Channels, Calcium-Activated; Ryanodine; Ryanodine Receptor Calcium Release Channel; Signal Transduction; Swine; Vasodilation; Vasodilator Agents | 2002 |
Central heme oxygenase-carbon monoxide pathway in the control of breathing under normoxia and hypoxia.
Topics: Animals; Carbon Monoxide; Deuteroporphyrins; Enzyme Inhibitors; Heme; Heme Oxygenase (Decyclizing); Hypoxia; Injections, Intraventricular; Lysine; Male; Rats; Rats, Wistar; Respiration; Tidal Volume; Time Factors; Ventilation | 2002 |
Structure-based mechanism of O2 sensing and ligand discrimination by the FixL heme domain of Bradyrhizobium japonicum.
Topics: Arginine; Bacterial Proteins; Bradyrhizobium; Carbon Monoxide; Crystallography, X-Ray; Cyanides; Ferric Compounds; Ferrous Compounds; Heme; Hemeproteins; Histidine Kinase; Hydrogen Bonding; Imidazoles; Isomerism; Ligands; Oxidation-Reduction; Oxygen; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Structure-Activity Relationship | 2002 |
The reactivity of alpha-hydroxyhaem and verdohaem bound to haem oxygenase-1 to dioxygen and sodium dithionite.
Topics: Carbon Monoxide; Dithionite; Electron Spin Resonance Spectroscopy; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Macromolecular Substances; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Oxygen; Porphyrins; Spectrophotometry; Spectrophotometry, Infrared | 2002 |
The antithyroid agent 6-n-propyl-2-thiouracil is a mechanism-based inactivator of the neuronal nitric oxide synthase isoform.
Topics: Animals; Antithyroid Agents; Arginine; Biopterins; Calcium; Calmodulin; Carbon Monoxide; Carbon Radioisotopes; Citrulline; Enzyme Activation; Enzyme Inhibitors; Heme; Kinetics; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pituitary Neoplasms; Propylthiouracil; Rats; Thiouracil; Tumor Cells, Cultured | 2002 |
Induction of heme oxygenase 1 by Ginkgo biloba in neuronal cultures and potential implications in ischemia.
Topics: Animals; Antioxidants; Carbon Monoxide; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Induction; Ginkgo biloba; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Ischemia; Membrane Proteins; Mice; Neurons; Neuroprotective Agents; Plant Extracts | 2002 |
Fine-tuning of the binding and dissociation of CO by the amino acids of the heme pocket of Coprinus cinereus peroxidase.
Topics: Amino Acid Substitution; Amino Acids; Anions; Arginine; Asparagine; Aspartic Acid; Carbon Monoxide; Coprinus; Cytochrome-c Peroxidase; Ferrous Compounds; Heme; Kinetics; Ligands; Mutation; Peroxidase; Phenylalanine; Protein Binding; Spectrophotometry, Infrared; Spectrum Analysis, Raman | 2002 |
Distal Cu ion protects synthetic heme/Cu analogues of cytochrome oxidase against inhibition by CO and cyanide.
Topics: Animals; Binding Sites; Carbon Monoxide; Catalysis; Cattle; Copper; Cyanides; Electron Transport Complex IV; Heme; Ions; Iron; Molecular Structure; Oxidation-Reduction; Oxygen | 2002 |
NO-induced activation mechanism of the heme-regulated eIF2alpha kinase.
Topics: Carbon Monoxide; eIF-2 Kinase; Electron Spin Resonance Spectroscopy; Enzyme Activation; Heme; Histidine; Nitric Oxide; Protein Conformation; Protein Structure, Tertiary; Spectrum Analysis, Raman | 2002 |
Endogenous carbon monoxide is an endothelial-derived vasodilator factor in the mesenteric circulation.
Topics: Animals; Aorta; Blotting, Western; Carbon Monoxide; Dose-Response Relationship, Drug; Endothelium, Vascular; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Lysine; Male; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Splanchnic Circulation; Vasodilation; Vasodilator Agents | 2003 |
NPAS2: a gas-responsive transcription factor.
Topics: Animals; ARNTL Transcription Factors; Basic Helix-Loop-Helix Transcription Factors; Carbon Monoxide; Circadian Rhythm; Dimerization; DNA; Helix-Loop-Helix Motifs; Heme; Ligands; Myoglobin; NADP; Nerve Tissue Proteins; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Spectrophotometry, Ultraviolet; Transcription Factors | 2002 |
Pigments of rat liver microsomes.
Topics: Animals; Carbon Monoxide; Cytochromes b5; Flavins; Heme; Hemin; Methemoglobin; Microsomes, Liver; Pigments, Biological; Rats; Rats, Wistar; Spectrophotometry | 2003 |
Studies on pig liver microsomes I. Enzymic and pigment composition of different microsomal fractions.
Topics: Animals; Carbon Monoxide; Centrifugation; Cytochromes b5; Dose-Response Relationship, Drug; Electrons; Enzymes; Heme; Hemoglobins; Hydrogen-Ion Concentration; Kinetics; Lipid Metabolism; Microscopy, Electron; Microsomes, Liver; Pigments, Biological; Protein Binding; Spectrophotometry; Swine | 2003 |
Spin-dependent mechanism for diatomic ligand binding to heme.
Topics: Carbon Monoxide; Heme; Ligands; Models, Molecular; Nitric Oxide; Oxygen; Thermodynamics | 2002 |
Mechanism-based inactivation of cytochromes P450 2E1 and 2E1 T303A by tert-butyl acetylenes: characterization of reactive intermediate adducts to the heme and apoprotein.
Topics: Acetylene; Alkylation; Amino Acid Substitution; Animals; Apoproteins; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Heme; Hydroxylation; Kinetics; NADP; Rabbits; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Substrate Specificity | 2002 |
Distal heme pocket regulation of ligand binding and stability in soybean leghemoglobin.
Topics: Amino Acids; Animals; Binding Sites; Carbon Monoxide; Cyanides; Glycine max; Heme; Histidine; Leghemoglobin; Ligands; Models, Molecular; Mutation; Myoglobin; Oxygen; Protein Conformation; Soybean Proteins; Thermodynamics; Water; Whales | 2003 |
Circadian rhythms. Carbon monoxide and clocks.
Topics: Animals; ARNTL Transcription Factors; Autonomic Nervous System; Basic Helix-Loop-Helix Transcription Factors; Behavior, Animal; Brain; Carbon Monoxide; Circadian Rhythm; CLOCK Proteins; Diffusion; Dimerization; DNA; Helix-Loop-Helix Motifs; Heme; Heme Oxygenase (Decyclizing); Mice; Models, Genetic; NAD; NADP; Nerve Tissue Proteins; Neurons; Neurotransmitter Agents; Oxidation-Reduction; Protein Structure, Tertiary; Synaptic Transmission; Trans-Activators; Transcription Factors; Transcription, Genetic | 2002 |
1H NMR structure of the heme pocket of HNO-myoglobin.
Topics: Animals; Binding Sites; Carbon Monoxide; Heme; Histidine; Horses; Models, Molecular; Muscle, Skeletal; Myoglobin; Nitrogen Oxides; Nuclear Magnetic Resonance, Biomolecular; Protons | 2003 |
Structure-function relationships in metalloproteins.
Topics: Calorimetry; Carbon Monoxide; Heme; Metalloproteins; Protein Conformation; Structure-Activity Relationship; Thermodynamics | 2003 |
Regulation of CO production in cerebral microvessels of newborn pigs.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aminolevulinic Acid; Animals; Animals, Newborn; Calcium; Calcium Signaling; Capillaries; Carbon Monoxide; Catalysis; Cerebrovascular Circulation; Cytosol; Enzyme Inhibitors; Genistein; Heme; Heme Oxygenase (Decyclizing); In Vitro Techniques; Ionomycin; Ionophores; Phosphorylation; Photosensitizing Agents; Swine; Tetradecanoylphorbol Acetate; Tyrphostins; Vanadates | 2003 |
Heme oxygenase-mediated vasodilation involves vascular smooth muscle cell hyperpolarization.
Topics: Animals; Biliverdine; Calcium Signaling; Carbon Monoxide; Cell Membrane; Colforsin; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Heme; Heme Oxygenase (Decyclizing); Large-Conductance Calcium-Activated Potassium Channels; Lysine; Male; Membrane Potentials; Mesenteric Arteries; Muscle, Smooth, Vascular; Potassium Channels, Calcium-Activated; Rats; Rats, Sprague-Dawley; Ryanodine; Vascular Resistance; Vasodilation | 2003 |
Reactions of Mycobacterium tuberculosis truncated hemoglobin O with ligands reveal a novel ligand-inclusive hydrogen bond network.
Topics: Bacterial Proteins; Binding Sites; Carbon Monoxide; Heme; Hemoglobins; Hydrogen Bonding; Kinetics; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Nitric Oxide; Oxygen; Recombinant Proteins; Truncated Hemoglobins | 2003 |
Interaction with membrane lipids and heme ligand binding properties of Escherichia coli flavohemoglobin.
Topics: Carbon Monoxide; Dihydropteridine Reductase; Escherichia coli; Escherichia coli Proteins; Heme; Hemeproteins; Iron; Kinetics; Ligands; Membrane Lipids; NADH, NADPH Oxidoreductases; Oxygen; Protein Binding; Recombinant Proteins; Spectrophotometry; Thermodynamics | 2003 |
Role of the interdomain linker probed by kinetics of CO ligation to an endothelial nitric oxide synthase mutant lacking the calmodulin binding peptide (residues 503-517 in bovine).
Topics: Amino Acid Sequence; Animals; Calmodulin; Carbon Monoxide; Cattle; Dimerization; Electrons; Gene Deletion; Heme; Kinetics; Models, Molecular; Molecular Sequence Data; Mutation; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Peptides; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Ultraviolet Rays | 2003 |
Ligand binding dynamics to the heme domain of the oxygen sensor Dos from Escherichia coli.
Topics: Biochemical Phenomena; Biochemistry; Carbon Monoxide; Carrier Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Hemeproteins; Kinetics; Ligands; Light; Models, Chemical; Nitric Oxide; Oxygen; Protein Binding; Protein Structure, Tertiary; Spectrophotometry; Time Factors | 2003 |
Ligand dynamics in a protein internal cavity.
Topics: Animals; Biophysical Phenomena; Biophysics; Carbon Monoxide; Heme; In Vitro Techniques; Models, Molecular; Myoglobin; Point Mutation; Protein Conformation; Proteins; Quantum Theory; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Static Electricity; Thermodynamics | 2003 |
Mechanism of low-density lipoprotein oxidation by hemoglobin-derived iron.
Topics: Animals; Apolipoproteins B; Carbon Monoxide; Cattle; Dansyl Compounds; Heme; Hemopexin; Horseradish Peroxidase; Horses; Humans; Hydrogen Peroxide; Iron; Kinetics; Lipoproteins, LDL; Methemoglobin; Metmyoglobin; Oxidation-Reduction; Spectrometry, Fluorescence; Thiobarbituric Acid Reactive Substances | 2003 |
Activation mechanism of the CO sensor CooA. Mutational and resonance Raman spectroscopic studies.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Biosensing Techniques; Carbon Monoxide; Heme; Hemeproteins; Hydrogen Bonding; Hydrogen-Ion Concentration; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Protein Conformation; Recombinant Proteins; Spectrum Analysis, Raman; Trans-Activators | 2003 |
Stereoselectivity of each of the three steps of the heme oxygenase reaction: hemin to meso-hydroxyhemin, meso-hydroxyhemin to verdoheme, and verdoheme to biliverdin.
Topics: Animals; Biliverdine; Carbon Monoxide; Ferrous Compounds; Heme; Heme Oxygenase (Decyclizing); Hemin; Hydroxylation; Oxidation-Reduction; Rats; Spectrophotometry; Stereoisomerism | 2003 |
Watching a protein as it functions with 150-ps time-resolved x-ray crystallography.
Topics: Amino Acid Substitution; Animals; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Fourier Analysis; Heme; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Myoglobin; Photolysis; Protein Conformation; Spectrophotometry, Infrared; Time Factors; Whales | 2003 |
Flavohemoglobin Hmp, but not its individual domains, confers protection from respiratory inhibition by nitric oxide in Escherichia coli.
Topics: Amino Acid Sequence; Binding Sites; Carbon Monoxide; Cell-Free System; Dihydropteridine Reductase; Escherichia coli; Escherichia coli Proteins; Genotype; Heme; Hemeproteins; Kinetics; Molecular Sequence Data; NADH, NADPH Oxidoreductases; Nitric Oxide; Nitroprusside; Oxygen Consumption; Peptide Fragments; Sequence Alignment; Sequence Homology, Amino Acid | 2003 |
Methods for measurements of heme oxygenase (HO) isoforms-mediated synthesis of carbon monoxide and HO-1 and HO-2 proteins.
Topics: Blotting, Western; Carbon Monoxide; Cell Line; DNA, Antisense; Gas Chromatography-Mass Spectrometry; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Isoenzymes; Membrane Proteins; Microchemistry; Oxidative Stress; Retroviridae; Transduction, Genetic | 2003 |
Effects of exogenous heme on renal function: role of heme oxygenase and cyclooxygenase.
Topics: Animals; Blood Pressure; Carbon Monoxide; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Heme; Heme Oxygenase (Decyclizing); Kidney; Male; Meclofenamic Acid; Metalloporphyrins; Prostaglandin-Endoperoxide Synthases; Prostaglandins F; Rats; Rats, Sprague-Dawley; Renal Circulation; Vascular Resistance | 2003 |
Structural dynamics of myoglobin: spectroscopic and structural characterization of ligand docking sites in myoglobin mutant L29W.
Topics: Amino Acid Substitution; Animals; Binding Sites; Carbon Monoxide; Heme; Kinetics; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Myoglobin; Oxygen; Photolysis; Protein Conformation; Recombinant Proteins; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Temperature; Whales | 2003 |
Structural dynamics of myoglobin: effect of internal cavities on ligand migration and binding.
Topics: Amino Acid Substitution; Animals; Binding Sites; Carbon Monoxide; Heme; Kinetics; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Myoglobin; Oxygen; Photolysis; Protein Binding; Recombinant Proteins; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Temperature; Whales | 2003 |
CO binding study of mouse heme-regulated eIF-2alpha kinase: kinetics and resonance Raman spectra.
Topics: Animals; Carbon Monoxide; eIF-2 Kinase; Heme; Kinetics; Mice; Spectrophotometry; Spectrum Analysis, Raman | 2003 |
Synthesis, characterization, and laser flash photolysis reactivity of a carbonmonoxy heme complex.
Topics: Carbon Monoxide; Crystallography, X-Ray; Ferrous Compounds; Heme; Kinetics; Lasers; Magnetic Resonance Spectroscopy; Metalloporphyrins; Photolysis; Spectrophotometry, Infrared | 2003 |
Crystal structures of ferrous and CO-, CN(-)-, and NO-bound forms of rat heme oxygenase-1 (HO-1) in complex with heme: structural implications for discrimination between CO and O2 in HO-1.
Topics: Animals; Carbon Monoxide; Crystallography, X-Ray; Cyanides; Ferrous Compounds; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hydrogen Bonding; Models, Molecular; Molecular Structure; Nitric Oxide; Oxidation-Reduction; Oxygen; Protein Binding; Protein Conformation; Rats | 2003 |
Inversion of axial coordination in myoglobin to create a "proximal" ligand binding pocket.
Topics: Amino Acid Substitution; Animals; Binding Sites; Carbon Monoxide; Cyanides; Ferric Compounds; Ferrous Compounds; Heme; Hydrogen-Ion Concentration; Kinetics; Ligands; Models, Molecular; Myoglobin; Protein Binding; Recombinant Proteins; Spectrophotometry; Spectrum Analysis, Raman; Swine | 2003 |
The equilibrium between cytochrome oxidase and carbon monoxide.
Topics: Carbon Monoxide; Electron Transport Complex IV; Heme; Hemoglobins; Oxidation-Reduction; Oxidoreductases; Oxygen; Proteins | 1957 |
Kinetics and equilibria in systems containing haem, carbon monoxide and pyridine.
Topics: Carbon Monoxide; Heme; Kinetics; Pyridines | 1959 |
Fractional solubilization of haemoproteins and partial purification of carbon monoxide-binding cytochrome from liver microsomes.
Topics: Carbon Monoxide; Cytochromes; Heme; Microsomes, Liver | 1963 |
ON THE ANOMALOUS INTERACTIONS OF LIGANDS WITH RHODOSPIRILLUM HAEM PROTEIN.
Topics: Azides; Bacterial Proteins; Carbon Monoxide; Chelating Agents; Cyanides; Fluorides; Heme; Hemeproteins; Hydrazines; Hydroxylamines; Ligands; Nitrites; Nitrogen; Nitrogen Dioxide; Nitroso Compounds; Pharmacology; Porphyrins; Research; Rhodospirillum | 1963 |
THE CHROMATOGRAPHY OF HEMINS FROM NORMAL AND ABNORMAL HUMAN ERYTHROCYTES.
Topics: Acetone; Acid-Base Equilibrium; Anemia; Anemia, Hemolytic; Anemia, Hypochromic; Carbon Monoxide; Chromatography; Erythrocytes; Heme; Hemin; Hemoglobins; Hemoglobins, Abnormal; Humans; Myoglobin; Research; Silicon Dioxide; Spectrophotometry; Spherocytosis, Hereditary; Thalassemia | 1964 |
STUDIES OF THE ELECTRON TRANSPORT SYSTEM. LV. THE INFLUENCE OF PH AND OF PROTEIN-DEPOLYMERIZING REAGENTS ON THE REACTION OF CYTOCHROME A WITH BOROHYDRIDE.
Topics: Borates; Borohydrides; Carbon Monoxide; Cyanides; Cytochromes; Cytochromes a; Dialysis; Electron Transport; Electron Transport Complex IV; Heme; Hydrogen-Ion Concentration; Indicators and Reagents; Renal Dialysis; Research; Spectrophotometry; Surface-Active Agents; Urea | 1964 |
THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE.
Topics: Animals; Carbon Monoxide; Cytochromes; Heme; Liver; Microsomes; Microsomes, Liver; NAD; Pigments, Biological; Rabbits; Research; Spectrophotometry | 1964 |
THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. II. SOLUBILIZATION, PURIFICATION, AND PROPERTIES.
Topics: Animals; Carbon Dioxide; Carbon Monoxide; Chemistry Techniques, Analytical; Chromatography; Cytochromes; Heme; Lipase; Liver; Microsomes; Microsomes, Liver; NAD; Oxidation-Reduction; Pigments, Biological; Rabbits; Research; Snakes; Spectrophotometry; Venoms | 1964 |
ON THE MOLECULAR MECHANISM OF ENERGY CONVERSION: OXIDATIVE PHOSPHORYLATION THROUGH A HEME-LINKED FORMYL GROUP.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Biochemical Phenomena; Biochemistry; Carbon Monoxide; Heme; Imidazoles; Metabolism; Oxidative Phosphorylation; Phosphates; Porphyrins; Research | 1964 |
ON THE CARBON MONOXIDE-SHIFT OF ABSORPTION SPECTRUM OF CYTOCHROMA A3.
Topics: Carbon Monoxide; Cytochromes; Electron Transport Complex IV; Heme; Hemoglobins; Peroxidases; Research; Spectrum Analysis | 1964 |
EFFECT OF ALKALI AND BOROHYDRIDE ON CARDIAC CYTOCHROME OXIDASE. FORMATION OF SCHIFF BASE.
Topics: Alkalies; Borohydrides; Carbon Monoxide; Chemical Phenomena; Chemistry; Electron Transport Complex IV; Heart; Heme; Hydrogen-Ion Concentration; Indicators and Reagents; Myocardium; Research; Schiff Bases; Spectrophotometry | 1965 |
RECONSTITUTION OF CYTOCHROME OXIDASE FROM CYTOCHROME A AND HEMATIN A.
Topics: Biochemical Phenomena; Biochemistry; Carbon Monoxide; Cytochromes; Cytochromes a; Electron Transport Complex IV; Heme; Hemin; Polarography; Research; Spectrophotometry; Sulfites | 1964 |
CYTOCHROME C OXIDASE COMPONENTS. VII. AN EVALUATION OF THE CARBON MONOXIDE-COMBINING CAPACITY IN ORDER TO DETERMINE THE STOICHIOMETRY OF CYTOCHROMES A AND A3.
Topics: Carbon Monoxide; Chemical Phenomena; Chemistry; Cytochromes; Cytochromes a; Electron Transport Complex IV; Heme; Hemoglobins; Research; Spectrum Analysis | 1965 |
HEME A COMPOUNDS AS SPECTRAL MODELS FOR CYTOCHROMES A AND A3.
Topics: Biochemical Phenomena; Biochemistry; Carbon Monoxide; Cyanides; Cytochromes; Cytochromes a; Electron Transport Complex IV; Heme; Hemoglobins; Imidazoles; Models, Theoretical; Peroxidases; Porphyrins; Pyridines; Research; Spectrophotometry | 1965 |
THE A3: TOTAL HEME A RATIO IN CYTOCHROME AA3 OF HEART MUSCLE.
Topics: Biochemical Phenomena; Biochemistry; Carbon Monoxide; Electron Transport Complex IV; Heme; Myocardium; Polarography; Research; Spectrum Analysis | 1965 |
HAEMOPROTEINS AND HAEM SYNTHESIS IN FACULTATIVE PHOTOSYNTHETIC AND DENITRIFYING BACTERIA.
Topics: Bacteriochlorophylls; Carbon Monoxide; Cytochrome c Group; Cytochromes; Denitrification; Ferrochelatase; Heme; Hydro-Lyases; Metabolism; Micrococcus; Oxidation-Reduction; Photosynthesis; Research; Rhodobacter sphaeroides; Rhodopseudomonas; Rhodospirillum; Spectrophotometry | 1965 |
Complex interactions of carbon monoxide with reduced cytochrome cbb3 oxidase from Pseudomonas stutzeri.
Topics: Binding Sites; Carbon Monoxide; Electron Transport Complex IV; Heme; Kinetics; Ligands; Oxidation-Reduction; Photolysis; Protein Subunits; Pseudomonas; Recombinant Proteins; Spectrophotometry | 2003 |
The rate of O2 and CO binding to a copper complex, determined by a "flash-and-trap" technique, exceeds that for hemes.
Topics: Carbon Monoxide; Copper; Heme; Kinetics; Organometallic Compounds; Oxygen; Photolysis; Pyridines; Thermodynamics | 2003 |
Solvent dependent and independent motions of CO-horseradish peroxidase examined by infrared spectroscopy and molecular dynamics calculations.
Topics: Arginine; Binding Sites; Carbon Monoxide; Heme; Histidine; Horseradish Peroxidase; Hydrogen-Ion Concentration; Hydroxamic Acids; Models, Molecular; Movement; Solvents; Spectrophotometry, Infrared; Temperature | 2003 |
Spectral analyses of cytochromes P450.
Topics: Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Iron; Spectrophotometry | 1998 |
Water-hydroxide exchange reactions at the catalytic site of heme-copper oxidases.
Topics: Animals; Carbon Monoxide; Catalytic Domain; Cattle; Copper; Electron Spin Resonance Spectroscopy; Electron Transport; Electron Transport Complex IV; Heme; Hydrogen-Ion Concentration; Hydroxides; Ligands; Myocardium; Oxidation-Reduction; Oxidoreductases; Photolysis; Rhodobacter sphaeroides; Water | 2003 |
Binding of oxygen and carbon monoxide to a heme-regulated phosphodiesterase from Escherichia coli. Kinetics and infrared spectra of the full-length wild-type enzyme, isolated PAS domain, and Met-95 mutants.
Topics: Carbon Monoxide; Carrier Proteins; Catalysis; Cloning, Molecular; Escherichia coli; Escherichia coli Proteins; Heme; Kinetics; Light; Methionine; Mutation; Oxidation-Reduction; Oxygen; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Time Factors | 2004 |
Compressibility and uncoupling of cytochrome P450cam: high pressure FTIR and activity studies.
Topics: Camphor 5-Monooxygenase; Carbon Monoxide; Enzyme Activation; Heme; Hydrogen Peroxide; Hydrostatic Pressure; Protein Conformation; Protein Denaturation; Spectroscopy, Fourier Transform Infrared; Static Electricity; Substrate Specificity | 2003 |
Ligand binding in a docking site of cytochrome C oxidase: a time-resolved step-scan Fourier transform infrared study.
Topics: Bacterial Proteins; Binding Sites; Carbon Monoxide; Electron Transport Complex IV; Heme; Ligands; Photolysis; Spectroscopy, Fourier Transform Infrared; Thermus thermophilus | 2003 |
Theoretical investigation of infrared spectra and pocket dynamics of photodissociated carbonmonoxy myoglobin.
Topics: Binding Sites; Biophysics; Carbon; Carbon Monoxide; Heme; Ligands; Light; Models, Chemical; Models, Molecular; Mutation; Myoglobin; Oxygen; Protein Conformation; Software; Time Factors | 2003 |
Residues in the distal heme pocket of neuroglobin. Implications for the multiple ligand binding steps.
Topics: Amino Acid Sequence; Base Sequence; Binding Sites; Carbon Monoxide; Cloning, Molecular; DNA; Electrophoresis, Polyacrylamide Gel; Globins; Heme; Histidine; Humans; Hydrogen-Ion Concentration; Kinetics; Ligands; Lysine; Models, Chemical; Molecular Sequence Data; Mutation; Myoglobin; Nerve Tissue Proteins; Neuroglobin; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrophotometry; Spectrum Analysis, Raman; Time Factors | 2004 |
Time-resolved resonance Raman and time-resolved step-scan FTIR studies of nitric oxide reductase from Paracoccus denitrificans: comparison of the heme b3-FeB site to that of the heme-CuB in oxidases.
Topics: Carbon Monoxide; Copper; Electron Transport Complex IV; Heme; Iron; Ligands; Oxidoreductases; Paracoccus denitrificans; Photolysis; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermodynamics | 2003 |
Role of ligand bending in the photodissociation of O2 vs CO-heme: a time-dependent density functional study.
Topics: Carbon Monoxide; Heme; Molecular Conformation; Myoglobin; Oxygen; Photochemistry; Thermodynamics | 2003 |
Distal heme pocket conformers of carbonmonoxy derivatives of Ascaris hemoglobin: evidence of conformational trapping in porous sol-gel matrices.
Topics: Animals; Ascaris; Binding Sites; Carbon Monoxide; Fluorescence Resonance Energy Transfer; Heme; Hemoglobins; Hydrogen; Hydrogen Bonding; Ligands; Models, Chemical; Models, Molecular; Mutation; Protein Conformation; Spectrophotometry; Spectrum Analysis, Raman | 2004 |
Proton linkage for CO binding and redox properties of bovine lactoperoxidase.
Topics: Animals; Binding Sites; Carbon Monoxide; Catalysis; Cattle; Enzyme Activation; Heme; Hydrogen-Ion Concentration; Kinetics; Lactoperoxidase; Milk; Oxidation-Reduction; Protein Binding; Protons | 2004 |
Heme oxygenase-1 modulates the expression of adhesion molecules associated with endothelial cell activation.
Topics: Adenoviridae; Animals; Bilirubin; Carbon Monoxide; Cattle; Cell Adhesion Molecules; Cells, Cultured; Down-Regulation; E-Selectin; Endothelium, Vascular; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Humans; Intercellular Adhesion Molecule-1; Iron Chelating Agents; MAP Kinase Signaling System; Membrane Proteins; Mitogen-Activated Protein Kinases; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Recombinant Proteins; Swine; Transduction, Genetic; Tumor Necrosis Factor-alpha; Up-Regulation; Vascular Cell Adhesion Molecule-1 | 2004 |
Heme as an optical probe of a conformational transition of ovine recPrP.
Topics: Animals; Carbon Monoxide; Fluorescent Dyes; Heme; Peptides; Prions; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Sheep; Spectrometry, Fluorescence; Temperature; Tryptophan; Tyrosine | 2004 |
Roles of heme axial ligands in the regulation of CO binding to CooA.
Topics: Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins; Base Sequence; Carbon Monoxide; Heme; Hemeproteins; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Conformation; Restriction Mapping; Rhodospirillum rubrum; Sequence Alignment; Sequence Homology, Nucleic Acid; Spectrum Analysis, Raman; Trans-Activators | 2004 |
Kinetic proofreading by the cavity system of myoglobin: protection from poisoning.
Topics: Animals; Biochemical Phenomena; Biochemistry; Carbon Monoxide; Carbon Monoxide Poisoning; Crystallography, X-Ray; Electron Transport Complex IV; Heme; Kinetics; Ligands; Models, Biological; Models, Chemical; Models, Molecular; Muscle Cells; Myoglobin; Whales; Xenon | 2004 |
The mechanism-based inactivation of p450 2B4 by tert-butyl 1-methyl-2-propynyl ether: structural determination of the adducts to the p450 heme.
Topics: Animals; Carbon Monoxide; Chromatography, Liquid; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ethers; Heme; Magnetic Resonance Spectroscopy; Mass Spectrometry; Rabbits | 2004 |
Noninvasive auto-photoreduction used as a tool for studying structural changes in heme-copper oxidases by FTIR spectroscopy.
Topics: Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome b Group; Electrochemistry; Electron Transport Complex IV; Electrons; Escherichia coli; Heme; Lasers; Light; Oxidation-Reduction; Oxidoreductases; Photochemistry; Protein Conformation; Rhodobacter sphaeroides; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Time Factors | 2004 |
Conversion of the 2,2,6,6-tetramethylpiperidine moiety to a 2,2-dimethylpyrrolidine by cytochrome P450: evidence for a mechanism involving nitroxide radicals and heme iron.
Topics: Aerobiosis; Anaerobiosis; Carbon Monoxide; Cyclic N-Oxides; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Deferoxamine; Free Radicals; Heme; Hemin; Humans; Iron; Iron Chelating Agents; Microsomes, Liver; NADP; Nitrogen Oxides; Oxygen Isotopes; Piperidones; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Triacetoneamine-N-Oxyl | 2004 |
Expression, purification, and characterization of Bacillus subtilis cytochromes P450 CYP102A2 and CYP102A3: flavocytochrome homologues of P450 BM3 from Bacillus megaterium.
Topics: Bacillus megaterium; Bacillus subtilis; Bacterial Proteins; Carbon Monoxide; Cloning, Molecular; Coenzymes; Cytochrome P-450 Enzyme System; Fatty Acids; Flavoproteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Heme; Hydroxylation; Kinetics; Mixed Function Oxygenases; Myristic Acid; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Protein Binding; Sequence Alignment; Sequence Homology, Amino Acid; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet | 2004 |
Proximal and distal influences on ligand binding kinetics in microperoxidase and heme model compounds.
Topics: Animals; Carbon Monoxide; Heart; Heme; Histidine; Horses; Imidazoles; Kinetics; Ligands; Models, Molecular; Myoglobin; Peroxidases; Photolysis; Protein Binding; Protein Conformation; Protoporphyrins; Spectrum Analysis, Raman; Time Factors | 2004 |
Extended molecular dynamics simulation of the carbon monoxide migration in sperm whale myoglobin.
Topics: Animals; Carbon Monoxide; Computer Simulation; Heme; Ligands; Male; Models, Molecular; Myoglobin; Spermatozoa; Thermodynamics; Whales | 2004 |
Heme environment in aldoxime dehydratase involved in carbon-nitrogen triple bond synthesis.
Topics: Carbon; Carbon Monoxide; Heme; Hydro-Lyases; Nitrogen; Spectrum Analysis, Raman | 2004 |
Orientational distribution of CO before and after photolysis of MbCO and HbCO: a determination using time-resolved polarized Mid-IR spectroscopy.
Topics: Animals; Anisotropy; Carbon Monoxide; Heme; Hemoglobin A; Hemoglobins; Humans; Hydrogen-Ion Concentration; Myoglobin; Photolysis; Spectrophotometry, Infrared; Temperature; Time Factors | 2004 |
Analysis of the kinetics of CO binding to neuronal nitric oxide synthase by flash photolysis: dual effects of substrates, inhibitors, and tetrahydrobiopterin.
Topics: Animals; Biopterins; Carbon Monoxide; Enzyme Inhibitors; Heme; Kinetics; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Photolysis; Protein Binding; Protein Structure, Tertiary; Rats | 2004 |
CO exchange of the oxyferrous complexes of endothelial nitric-oxide synthase oxygenase domain in the presence of 4-amino-tetrahydrobiopterin.
Topics: Animals; Biopterins; Carbon Monoxide; Cattle; Ferrous Compounds; Heme; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Oxidation-Reduction; Protein Structure, Tertiary | 2004 |
Viscosity-dependent relaxation significantly modulates the kinetics of CO recombination in the truncated hemoglobin TrHbN from Mycobacterium tuberculosis.
Topics: Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Glycerol; Heme; Hemoglobins; Kinetics; Ligands; Models, Chemical; Models, Molecular; Mutation; Mycobacterium tuberculosis; Protein Binding; Protein Conformation; Recombination, Genetic; Temperature; Time Factors; Truncated Hemoglobins; Water | 2004 |
Fifth-order contributions to ultrafast spectrally resolved vibrational echoes: heme-CO proteins.
Topics: Carbon Monoxide; Computer Simulation; Heme; Hemoglobins; Models, Chemical; Models, Molecular; Myoglobin; Spectrum Analysis; Vibration | 2004 |
Spectroscopic characterization of the soluble guanylate cyclase-like heme domains from Vibrio cholerae and Thermoanaerobacter tengcongensis.
Topics: Amino Acid Sequence; Bacterial Proteins; Carbon Monoxide; Chemoreceptor Cells; Cloning, Molecular; Clostridium; Escherichia coli Proteins; Ferrous Compounds; Gene Expression Regulation, Bacterial; Guanylate Cyclase; Heme; Ligands; Molecular Sequence Data; Nitric Oxide; Oxygen; Protein Structure, Tertiary; Receptors, Cell Surface; Solubility; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Vibrio cholerae | 2004 |
Activation mechanisms of transcriptional regulator CooA revealed by small-angle X-ray scattering.
Topics: Amino Acids; Bacterial Proteins; Carbon Monoxide; Crystallography, X-Ray; Cyclic AMP; DNA; Gene Expression Regulation, Bacterial; Heme; Hemeproteins; Kinetics; Light; Models, Molecular; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Scattering, Radiation; Spectrophotometry; Trans-Activators; Transcriptional Activation; Ultraviolet Rays; X-Rays | 2004 |
Human heme oxygenase oxidation of 5- and 15-phenylhemes.
Topics: Animals; Ascorbic Acid; Benzoic Acid; Biliverdine; Carbon Monoxide; Chromatography, High Pressure Liquid; Chromatography, Liquid; Crystallography, X-Ray; Electrons; Esters; Heme; Heme Oxygenase (Decyclizing); Horses; Humans; Ions; Lysine; Mass Spectrometry; Methionine; Models, Chemical; Models, Molecular; Myoglobin; NADPH-Ferrihemoprotein Reductase; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Spectrophotometry; Stereoisomerism; Time Factors; Ultraviolet Rays | 2004 |
Investigations of photolysis and rebinding kinetics in myoglobin using proximal ligand replacements.
Topics: Amino Acid Substitution; Animals; Bromine; Carbon Monoxide; Glycine; Heme; Histidine; Imidazoles; Kinetics; Ligands; Models, Chemical; Myoglobin; Photolysis; Protein Binding; Pyridines; Spectrophotometry; Spectrum Analysis, Raman; Whales | 2004 |
CO vibration as a probe of ligand dissociation and transfer in myoglobin.
Topics: Biophysical Phenomena; Biophysics; Carbon Monoxide; Heme; Ligands; Models, Chemical; Myoglobin; Photochemistry; Vibration | 2004 |
The C-helix in CooA rolls upon CO binding to ferrous heme.
Topics: Bacterial Proteins; Carbon Monoxide; Databases as Topic; Escherichia coli; Heme; Hemeproteins; Humans; Iron; Leucine; Ligands; Models, Biological; Models, Molecular; Mutation; Oxidation-Reduction; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Rhodospirillum rubrum; Spectrum Analysis, Raman; Trans-Activators | 2004 |
Changing the ligand specificity of CooA, a highly specific heme-based CO sensor.
Topics: Carbon Monoxide; DNA; Escherichia coli Proteins; Fimbriae Proteins; Heme; Imidazoles; Ligands | 2004 |
The heme oxygenase system: past, present, and future.
Topics: Brain; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Isoenzymes | 2004 |
Why heme needs to be degraded to iron, biliverdin IXalpha, and carbon monoxide?
Topics: Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Humans; Iron; Isoenzymes | 2004 |
Stability of the heme environment of the nitric oxide synthase from Staphylococcus aureus in the absence of pterin cofactor.
Topics: Amino Acid Sequence; Animals; Arginine; Carbon Monoxide; Electrons; Heme; Humans; Molecular Sequence Data; Nitric Oxide Synthase; Protein Structure, Tertiary; Protons; Pterins; Sequence Homology, Amino Acid; Spectrophotometry; Spectrum Analysis, Raman; Staphylococcus aureus; Static Electricity; Tetrahydrofolates | 2004 |
Semihemoglobins, high oxygen affinity dimeric forms of human hemoglobin respond efficiently to allosteric effectors without forming tetramers.
Topics: Allosteric Site; Carbon Monoxide; Dimerization; Erythrocytes; Heme; Hemoglobins; Humans; Hydrogen-Ion Concentration; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Oxygen; Oxyhemoglobins; Protein Binding; Protein Conformation; Protein Structure, Quaternary; Spectrum Analysis, Raman; Time Factors; Ultracentrifugation | 2004 |
Evidence that haem iron in the malaria parasite is not needed for the antimalarial effects of artemisinin.
Topics: Animals; Antimalarials; Artemisinins; Carbon Monoxide; Chloroquine; Erythrocytes; Heme; Hemoglobins; Humans; Iron; Malaria; Oxidation-Reduction; Oxidative Stress; Oxygen; Plasmodium falciparum; Sesquiterpenes | 2004 |
Reactions of meso-hydroxyhemes with carbon monoxide and reducing agents in search of the elusive species responsible for the g = 2.006 resonance of carbon monoxide-treated heme oxygenase. Isolation of diamagnetic iron(II) complexes of octaethyl-meso-hydro
Topics: Carbon Monoxide; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Heme; Heme Oxygenase (Decyclizing); Magnetics; Metalloporphyrins; Models, Chemical; Models, Molecular; Molecular Conformation; Organometallic Compounds; Reducing Agents | 2004 |
Internal friction controls the speed of protein folding from a compact configuration.
Topics: Animals; Carbon Monoxide; Cytochromes c; Enzyme Stability; Ferrous Compounds; Heme; Horses; Protein Conformation; Protein Denaturation; Protein Folding; Solvents; Spectrophotometry; Thermodynamics; Viscosity | 2004 |
Role of Tyr-288 at the dioxygen reduction site of cytochrome bo studied by stable isotope labeling and resonance raman spectroscopy.
Topics: Carbon Monoxide; Catalysis; Copper; Cytochrome b Group; Escherichia coli; Escherichia coli Proteins; Heme; Histidine; Hydrogen; Ions; Kinetics; Metals; Models, Chemical; Models, Molecular; Nitrites; Oxygen; Quinone Reductases; Spectrophotometry; Spectrum Analysis, Raman; Temperature; Tyrosine | 2004 |
Spin-forbidden CO ligand recombination in myoglobin.
Topics: Carbon Monoxide; Heme; Models, Molecular; Myoglobin; Protein Conformation; Thermodynamics | 2004 |
Arginine 391 in subunit I of the cytochrome bd quinol oxidase from Escherichia coli stabilizes the reduced form of the hemes and is essential for quinol oxidase activity.
Topics: Amino Acid Sequence; Arginine; Binding Sites; Carbon Monoxide; Catalysis; Chromatography, High Pressure Liquid; Cytochrome b Group; Cytochromes; Electron Spin Resonance Spectroscopy; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; NADPH Oxidases; Oxidation-Reduction; Oxidoreductases; Oxygen; Potentiometry; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship; Tetramethylphenylenediamine; Ubiquinone | 2004 |
Disentangling ligand migration and heme pocket relaxation in cytochrome P450cam.
Topics: Binding Sites; Carbon Monoxide; Computer Simulation; Cytochrome P-450 Enzyme System; Heme; Kinetics; Ligands; Models, Chemical; Models, Molecular; Protein Binding | 2005 |
Investigation of the role of the N-terminal proline, the distal heme ligand in the CO sensor CooA.
Topics: Amino Acid Substitution; Bacterial Proteins; Carbon Monoxide; Circular Dichroism; DNA-Binding Proteins; Electron Spin Resonance Spectroscopy; Escherichia coli Proteins; Ferric Compounds; Ferrous Compounds; Fimbriae Proteins; Heme; Hemeproteins; Ligands; Oxidation-Reduction; Peptide Fragments; Proline; Protein Binding; Spectrophotometry; Trans-Activators | 2004 |
Carbon monoxide actuates O(2)-limited heme degradation in the rat brain.
Topics: Animals; Brain; Brain Chemistry; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Metalloporphyrins; Muscle, Skeletal; Myocardium; Oxygen; Protoporphyrins; Rats | 2004 |
Hemoxygenase-2 is an oxygen sensor for a calcium-sensitive potassium channel.
Topics: Animals; Carbon Monoxide; Carotid Body; Cell Hypoxia; Cell Line; Heme; Heme Oxygenase (Decyclizing); Humans; Immunoprecipitation; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; NADP; Oxygen; Patch-Clamp Techniques; Potassium Channels, Calcium-Activated; Rats; RNA Interference; RNA, Small Interfering; Transfection | 2004 |
The structure of carbonmonoxy neuroglobin reveals a heme-sliding mechanism for control of ligand affinity.
Topics: Amino Acid Sequence; Animals; Carbon Monoxide; Crystallography, X-Ray; Globins; Heme; Ligands; Mice; Models, Molecular; Nerve Tissue Proteins; Neuroglobin; Protein Binding; Protein Structure, Tertiary; Spectroscopy, Fourier Transform Infrared | 2004 |
Two CO molecules can bind concomitantly at the diiron site of NO reductase from Bacillus azotoformans.
Topics: Bacillus; Bacterial Proteins; Binding Sites; Carbon Monoxide; Chlorides; Heme; Nonheme Iron Proteins; Oxidoreductases; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2004 |
Mutational study of the bacterial hemoglobin distal heme pocket.
Topics: Bacterial Proteins; Binding Sites; Carbon Monoxide; Escherichia coli; Heme; Hemoglobins; Models, Molecular; Mutation; Oxygen; Protein Conformation; Spectroscopy, Fourier Transform Infrared; Truncated Hemoglobins; Vitreoscilla | 2005 |
Ligand binding properties of myoglobin reconstituted with iron porphycene: unusual O2 binding selectivity against CO binding.
Topics: Animals; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Heme; Kinetics; Ligands; Myoglobin; Oxygen; Porphyrins; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Substrate Specificity; Whales | 2004 |
Cell biology. Oxygen sensing: it's a gas!
Topics: Animals; Carbon Monoxide; Carotid Body; Cell Hypoxia; Cell Membrane; Cells, Cultured; Heme; Heme Oxygenase (Decyclizing); Hemeproteins; Large-Conductance Calcium-Activated Potassium Channels; Membrane Potentials; Mitochondria; NADP; NADPH Oxidases; Oxidation-Reduction; Oxygen; Potassium Channels, Calcium-Activated; Proteomics; RNA, Small Interfering; Signal Transduction | 2004 |
The grapefruit juice effect is not limited to cytochrome P450 (P450) 3A4: evidence for bergamottin-dependent inactivation, heme destruction, and covalent binding to protein in P450s 2B6 and 3A5.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Beverages; Carbon Monoxide; Chromatography, High Pressure Liquid; Citrus; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Electrophoresis, Polyacrylamide Gel; Furocoumarins; Heme; In Vitro Techniques; Kinetics; Microsomes, Liver; Oxidoreductases, N-Demethylating; Protein Binding; Rats; Rats, Long-Evans; Spectrometry, Mass, Electrospray Ionization | 2005 |
The formation of carbon monoxide during peroxidation of microsomal lipids.
Topics: Animals; Carbon Monoxide; Heme; Intracellular Membranes; Lipid Metabolism; Lipid Peroxidation; Microsomes, Liver; Rats; Spectrum Analysis | 1976 |
The origin of stark splitting in the initial photoproduct state of MbCO.
Topics: Carbon Monoxide; Heme; Hydrogen Bonding; Models, Molecular; Myoglobin; Photolysis; Spectroscopy, Fourier Transform Infrared | 2005 |
Unusual ligand discrimination by a myoglobin reconstituted with a hydrophobic domain-linked heme.
Topics: Animals; Carbon Monoxide; Heme; Hydrophobic and Hydrophilic Interactions; Kinetics; Ligands; Myoglobin; Protein Structure, Tertiary; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity | 2005 |
Successful recombinant production of Allochromatium vinosum cytochrome c' requires coexpression of cmm genes in heme-rich Escherichia coli JCB712.
Topics: Carbon Monoxide; Carrier Proteins; Chromatiaceae; Chromatium; Chromatography, Gel; Cyanides; Cytochromes c'; Dimerization; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Gene Expression; Heme; Ligands; Maltose-Binding Proteins; Molecular Weight; Nitric Oxide; Periplasm; Recombinant Proteins; Spectrophotometry | 2005 |
Biophysical and kinetic characterization of HemAT, an aerotaxis receptor from Bacillus subtilis.
Topics: Bacillus subtilis; Bacterial Proteins; Biophysics; Carbon Monoxide; Circular Dichroism; Heme; Hydrogen-Ion Concentration; Kinetics; Leucine; Ligands; Models, Molecular; Mutation; Oxygen; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Signal Transduction; Spectrophotometry; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Temperature; Time Factors; Tryptophan; Tyrosine; Ultracentrifugation; Ultraviolet Rays | 2005 |
Resonance Raman evidence for the presence of two heme pocket conformations with varied activities in CO-bound bovine soluble guanylate cyclase and their conversion.
Topics: Allosteric Regulation; Animals; Carbon Monoxide; Cattle; Guanine Nucleotides; Guanylate Cyclase; Heme; Protein Binding; Spectrum Analysis, Raman | 2005 |
Mechanism of inactivation of inducible nitric oxide synthase by amidines. Irreversible enzyme inactivation without inactivator modification.
Topics: Amidines; Animals; Benzylamines; Biliverdine; Carbon Monoxide; Chromatography, High Pressure Liquid; Enzyme Activation; Enzyme Inhibitors; Heme; Horses; Humans; Kinetics; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Ornithine; Spectrometry, Mass, Electrospray Ionization | 2005 |
Light-induced relaxation of photolyzed carbonmonoxy myoglobin: a temperature-dependent x-ray absorption near-edge structure (XANES) study.
Topics: Animals; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Heme; Horses; Light; Models, Chemical; Models, Molecular; Myoglobin; Photolysis; Protein Binding; Protein Conformation; Recombination, Genetic; Software; Spectrometry, X-Ray Emission; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Temperature; X-Ray Diffraction; X-Rays | 2005 |
Role of arginine 220 in the oxygen sensor FixL from Bradyrhizobium japonicum.
Topics: Arginine; Bacterial Proteins; Bradyrhizobium; Carbon Monoxide; DNA; Electrons; Heme; Hemeproteins; Histidine Kinase; Hydrogen Bonding; Hypoxia; Kinetics; Ligands; Models, Chemical; Models, Molecular; Mutation; Oxygen; Protein Conformation; Protein Structure, Tertiary; Signal Transduction; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Time Factors; Ultraviolet Rays | 2005 |
Heme/non-heme diiron(II) complexes and O2, CO, and NO adducts as reduced and substrate-bound models for the active site of bacterial nitric oxide reductase.
Topics: Binding Sites; Biomimetic Materials; Carbon Monoxide; Ferrous Compounds; Heme; Iron Chelating Agents; Magnetic Resonance Spectroscopy; Nitric Oxide; Oxidoreductases; Oxygen; Porphyrins; Pyridines; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2005 |
Ligand, cofactor, and residue vibrations in the catalytic site of endothelial nitric oxide synthase.
Topics: Animals; Arginine; Carbon Monoxide; Catalytic Domain; Cattle; Coenzymes; Deuterium Exchange Measurement; Heme; Kinetics; Ligands; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitrogen; Nitrogen Isotopes; Nitrogen Radioisotopes; Photolysis; Spectroscopy, Fourier Transform Infrared; Thermodynamics | 2005 |
Ligand migration and protein fluctuations in myoglobin mutant L29W.
Topics: Amino Acid Substitution; Carbon Monoxide; Crystallography, X-Ray; Heme; In Vitro Techniques; Ligands; Models, Molecular; Mutation; Myoglobin; Photolysis; Protein Conformation; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Static Electricity; Temperature; Thermodynamics | 2005 |
Resonance Raman and infrared spectroscopic studies of high-output forms of human soluble guanylyl cyclase.
Topics: Carbon Monoxide; Enzyme Activation; Guanylate Cyclase; Heme; Humans; Indazoles; Isoenzymes; Protein Conformation; Pyrazoles; Pyridines; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Structure-Activity Relationship | 2005 |
CO-dependent activity-controlling mechanism of heme-containing CO-sensor protein, neuronal PAS domain protein 2.
Topics: Amino Acid Sequence; Animals; Basic Helix-Loop-Helix Transcription Factors; Carbon Monoxide; Cysteine; Cytochrome c Group; Dimerization; DNA; Heme; Histidine; Hydrogen Bonding; Hydrogen-Ion Concentration; Iron; Ligands; Liver; Mice; Mice, Inbred C57BL; Models, Chemical; Molecular Sequence Data; Mutation; Nerve Tissue Proteins; Neurons; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protons; Sequence Homology, Amino Acid; Signal Transduction; Spectrum Analysis, Raman; Time Factors; Transcription Factors | 2005 |
CO rebinding to protoheme: investigations of the proximal and distal contributions to the geminate rebinding barrier.
Topics: Carbon Monoxide; Entropy; Glycerol; Heme; Kinetics; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2005 |
Early events in the folding of four-helix-bundle heme proteins.
Topics: Carbon Monoxide; Circular Dichroism; Cytochromes b; Cytochromes c; Escherichia coli; Heme; Kinetics; Protein Conformation; Protein Folding; Spectrometry, Fluorescence | 2005 |
Molecular dynamics simulation of sperm whale myoglobin: effects of mutations and trapped CO on the structure and dynamics of cavities.
Topics: Animals; Biophysics; Carbon Monoxide; Crystallography, X-Ray; Heme; Histidine; Iron; Ligands; Light; Models, Molecular; Models, Statistical; Molecular Conformation; Mutation; Myoglobin; Oxygen; Photolysis; Protein Binding; Protein Conformation; Protein Structure, Secondary; Solvents; Whales | 2005 |
Photoinduced carbon monoxide migration in a synthetic heme-copper complex.
Topics: Carbon Monoxide; Copper; Heme; Iron Compounds; Kinetics; Models, Molecular; Photolysis; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet | 2005 |
Resonance raman investigation of the specific sensing mechanism of a target molecule by gas sensory proteins.
Topics: Biosensing Techniques; Carbon Dioxide; Carbon Monoxide; Catalysis; DNA; Electron Transport; Gases; Heme; Hemeproteins; Ligands; Molecular Structure; Mutation; Nitric Oxide; Oxygen; Protein Binding; Protein Conformation; Spectrum Analysis, Raman | 2005 |
Determination of carbon monoxide (CO) in rodent tissue: effect of heme administration and environmental CO exposure.
Topics: Animals; Arginine; Carbon Monoxide; Chromatography, Gas; Environmental Exposure; Heme; Male; Mice; Mice, Inbred BALB C; Rats; Rats, Wistar | 2005 |
Chemical kinetics measurements on the reaction between blood and ozone.
Topics: Absorption; Animals; Blood; Carbon Monoxide; Cattle; Heme; Hemoglobins; Iron; Kinetics; Macromolecular Substances; Male; Models, Chemical; Oxygen; Ozone; Spectrophotometry; Time Factors | 2005 |
Heme reduction by intramolecular electron transfer in cysteine mutant myoglobin under carbon monoxide atmosphere.
Topics: Animals; Carbon Monoxide; Cysteine; Dimerization; Disulfides; Electron Transport; Heme; Metmyoglobin; Mutagenesis, Site-Directed; Myoglobin; Oxidation-Reduction; Spectrophotometry, Ultraviolet; Static Electricity; Whales | 2005 |
Powered by gas--a ligand for a fruit fly nuclear receptor.
Topics: Animals; Carbon Monoxide; DNA-Binding Proteins; Drosophila melanogaster; Heme; Insect Proteins; Ligands; Nitric Oxide; Oxidation-Reduction; Receptors, Steroid | 2005 |
The Drosophila nuclear receptor e75 contains heme and is gas responsive.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbon Monoxide; Cell Line; Dimerization; DNA-Binding Proteins; Drosophila melanogaster; Drosophila Proteins; Heme; Humans; Insect Proteins; Ligands; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitric Oxide; Oxidation-Reduction; Protein Binding; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Transcription, Genetic | 2005 |
Electron/proton coupling in bacterial nitric oxide reductase during reduction of oxygen.
Topics: Binding Sites; Carbon Monoxide; Cytochrome c Group; Electron Transport; Heme; Ligands; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidoreductases; Oxygen; Oxygen Consumption; Paracoccus denitrificans; Photolysis; Protons; Substrate Specificity; Water | 2005 |
Light pulse-induced heme and iron-associated transcripts in mouse brain: a microarray analysis.
Topics: Animals; Biological Clocks; Brain; Carbon Monoxide; Cluster Analysis; Gene Expression Profiling; Gene Expression Regulation; Heme; Heme Oxygenase (Decyclizing); Hemoglobins; Humans; Iron; Light; Male; Mice; Mice, Inbred C57BL; NADPH-Ferrihemoprotein Reductase; Oligonucleotide Array Sequence Analysis; Oxidation-Reduction; Reproducibility of Results; Transcription, Genetic | 2005 |
Increased heme catabolism in critically ill patients: correlation among exhaled carbon monoxide, arterial carboxyhemoglobin, and serum bilirubin IXalpha concentrations.
Topics: Aged; Arteries; Bilirubin; Biomarkers; Carbon Monoxide; Carboxyhemoglobin; Critical Illness; Exhalation; Female; Heme; Humans; Male; Middle Aged; Osmolar Concentration | 2006 |
Interdomain interactions regulate the activation of the heme-regulated eIF 2 alpha kinase.
Topics: Amino Acid Substitution; Animals; Binding Sites; Carbon Monoxide; Cells, Cultured; eIF-2 Kinase; Enzyme Activation; Heme; Mutagenesis, Site-Directed; Nitric Oxide; Protein Binding; Protein Structure, Tertiary; Rabbits; Recombinant Proteins; Reticulocytes; Structure-Activity Relationship | 2005 |
Evidence for the hydrophobic cavity of heme oxygenase-1 to be a CO-trapping site.
Topics: 2-Propanol; Animals; Ascorbic Acid; Bacterial Proteins; Binding Sites; Carbon Monoxide; Heme; Heme Oxygenase-1; Humans; Hydrophobic and Hydrophilic Interactions; Membrane Proteins; Rats; Synechocystis | 2005 |
The position 68(E11) side chain in myoglobin regulates ligand capture, bond formation with heme iron, and internal movement into the xenon cavities.
Topics: Animals; Binding Sites; Carbon Monoxide; Glycerol; Heme; Histidine; Horses; Hydrogen-Ion Concentration; Kinetics; Ligands; Models, Chemical; Models, Molecular; Molecular Conformation; Mutation; Myocardium; Myoglobin; Phase Transition; Protein Binding; Protein Conformation; Recombination, Genetic; Sperm Whale; Stereoisomerism; Temperature; Time Factors; Xenon | 2005 |
Heme is a carbon monoxide receptor for large-conductance Ca2+-activated K+ channels.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbon Monoxide; Carrier Proteins; Chlorocebus aethiops; COS Cells; Heme; Heme-Binding Proteins; Hemeproteins; Hemin; Molecular Sequence Data; Oxygen; Potassium Channels, Calcium-Activated; Rats | 2005 |
Ultrahigh resolution structures of nitrophorin 4: heme distortion in ferrous CO and NO complexes.
Topics: Carbon Monoxide; Crystallography, X-Ray; Ferrous Compounds; Heme; Hemeproteins; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Nitric Oxide; Salivary Proteins and Peptides; Spectrophotometry; Water; Xenon | 2005 |
Inactivation of CYP2A6 and CYP2A13 during nicotine metabolism.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Escherichia coli; Half-Life; Heme; Humans; Kinetics; Mixed Function Oxygenases; NADP; Nicotine; Nicotinic Agonists; Rats; Substrate Specificity | 2006 |
Phytol-modified heme in mesoporous silica: conjugates as models of hemoproteins.
Topics: Adsorption; Biomimetic Materials; Carbon Monoxide; Heme; Hemeproteins; Hemin; Hydrogen Peroxide; Nanotechnology; Nitric Oxide; Nitrogen; Oxygen; Phytol; Porosity; Silicon Dioxide | 2006 |
Structural characterization of the proximal and distal histidine environment of cytoglobin and neuroglobin.
Topics: Carbon Monoxide; Crystallography; Cytoglobin; Globins; Heme; Histidine; Humans; Iron; Ligands; Light; Models, Chemical; Mutation; Nerve Tissue Proteins; Neuroglobin; Nitric Oxide; Photolysis; Protein Binding; Recombinant Proteins; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2005 |
The effectiveness of oral tin mesoporphyrin prophylaxis in reducing bilirubin production after an oral heme load in a transgenic mouse model.
Topics: Animals; Bilirubin; Carbon Monoxide; Disease Models, Animal; Heme; Heme Oxygenase-1; Hyperbilirubinemia; Metalloporphyrins; Mice; Mice, Transgenic; Transcription, Genetic | 2006 |
Heme carbonyls: environmental effects on nu(C-O) and Fe-C/C-O bond length correlations.
Topics: Carbon; Carbon Monoxide; Crystallography, X-Ray; Heme; Iron; Ligands; Metalloporphyrins; Models, Molecular; Oxygen | 2005 |
Carbon monoxide pretreatment prevents respiratory derangement and ameliorates hyperacute endotoxic shock in pigs.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Blood Coagulation; Carbon Monoxide; Carboxyhemoglobin; Disease Models, Animal; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Intercellular Adhesion Molecule-1; Interleukin-10; Lipopolysaccharides; Lung; Models, Biological; Oxygen; Respiration Disorders; Shock, Septic; Swine; Up-Regulation | 2005 |
Geminate carbon monoxide rebinding to a c-type haem.
Topics: Carbon Monoxide; Heme; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Myoglobin; Protein Binding | 2005 |
Structural characterization of the [Pco/o(2)] compound of cytochrome c oxidase.
Topics: Animals; Carbon Monoxide; Cattle; Electron Transport Complex IV; Heme; Molecular Structure; Oxidation-Reduction; Oxygen; Spectrum Analysis, Raman | 2005 |
Picosecond structural dynamics of myoglobin following photodissociation of carbon monoxide as revealed by ultraviolet time-resolved resonance Raman spectroscopy.
Topics: Carbon Monoxide; Heme; Models, Molecular; Myoglobin; Photolysis; Spectrum Analysis, Raman; Time Factors; Tryptophan; Tyrosine; Ultraviolet Rays | 2005 |
Identification of an Escherichia coli O157:H7 heme oxygenase with tandem functional repeats.
Topics: Carbon Monoxide; Crystallography, X-Ray; Escherichia coli O157; Heme; Heme Oxygenase (Decyclizing); Metalloporphyrins; Oxidation-Reduction; Protein Structure, Tertiary; Spectrophotometry; Tandem Repeat Sequences | 2005 |
O2 and CO binding properties of artificial hemoproteins formed by complexing iron protoporphyrin IX with human serum albumin mutants.
Topics: Amino Acid Substitution; Carbon Monoxide; Hemeproteins; Hemin; Humans; Iron; Models, Molecular; Mutagenesis, Site-Directed; Oxygen; Protoporphyrins; Serum Albumin | 2005 |
Biophysical properties of a c-type heme in chemotaxis signal transducer protein DcrA.
Topics: Amino Acid Sequence; Bacterial Proteins; Biophysical Phenomena; Biophysics; Carbon Monoxide; Chemotaxis; Electrochemistry; Heme; Membrane Proteins; Oxidation-Reduction; Protein Structure, Tertiary; Signal Transduction; Spectrophotometry; Spectrum Analysis, Raman | 2005 |
Soluble guanylyl cyclase: the nitric oxide receptor.
Topics: Animals; Baculoviridae; Base Sequence; Carbon Monoxide; Cell Line; DNA Primers; Electron Spin Resonance Spectroscopy; Guanylate Cyclase; Heme; Humans; Kinetics; Nitric Oxide; Protein Binding; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Soluble Guanylyl Cyclase; Spodoptera | 2005 |
The source of endogenous carbon monoxide formation in human placental chorionic villi.
Topics: Carbon Monoxide; Chorionic Villi; Female; Heme; Heme Oxygenase (Decyclizing); Humans; Placenta; Placental Circulation; Pregnancy; Up-Regulation | 2005 |
pH-dependent redox and CO binding properties of chelated protoheme-L-histidine and protoheme-glycyl-L-histidine complexes.
Topics: Carbon Monoxide; Chelating Agents; Dipeptides; Heme; Histidine; Hydrogen-Ion Concentration; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Thermodynamics | 2006 |
Crystal structure of human cytochrome P450 2D6.
Topics: Amino Acid Sequence; Aspartic Acid; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Cytochrome P-450 CYP2D6; Glutamic Acid; Heme; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Protein Conformation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Software; Subcellular Fractions; Substrate Specificity | 2006 |
Hemoglobin I from Lucina pectinata: a model for distal heme-ligand control.
Topics: Amino Acid Sequence; Animals; Bivalvia; Carbon Monoxide; Cyanides; Ferric Compounds; Ferrous Compounds; Heme; Hemoglobins; Kinetics; Ligands; Oxygen; Protein Structure, Tertiary; Spectroscopy, Fourier Transform Infrared | 2006 |
The Fe-CO bond energy in myoglobin: a QM/MM study of the effect of tertiary structure.
Topics: Animals; Carbon Monoxide; Computer Simulation; Heme; Humans; Iron; Models, Molecular; Myoglobin; Oxygen | 2006 |
Chronic CO levels have [corrected] a beneficial effect on vascular relaxation in diabetes.
Topics: Acetylcholine; Animals; Aorta; Biliverdine; Blotting, Western; Carbon Monoxide; Chromium; Densitometry; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Endothelium, Vascular; Femoral Artery; Guanylate Cyclase; Heme; Immunohistochemistry; Male; Mesoporphyrins; Muscle Contraction; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organometallic Compounds; Oxadiazoles; Oxidative Stress; Protoporphyrins; Pyrazines; Pyrroles; Quinoxalines; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Time Factors | 2006 |
Water and ligand entry in myoglobin: assessing the speed and extent of heme pocket hydration after CO photodissociation.
Topics: Animals; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Electrons; Heme; Histidine; Kinetics; Ligands; Models, Chemical; Models, Molecular; Mutation; Myoglobin; Recombinant Proteins; Spectrophotometry; Sperm Whale; Temperature; Thermodynamics; Time Factors; Water; X-Rays | 2006 |
Evidence for displacements of the C-helix by CO ligation and DNA binding to CooA revealed by UV resonance Raman spectroscopy.
Topics: Bacterial Proteins; Carbon Monoxide; DNA; Electrons; Heme; Hemeproteins; Iron; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; Protein Structure, Secondary; Rhodospirillum rubrum; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman; Time Factors; Trans-Activators; Tryptophan; Ultraviolet Rays | 2006 |
Resonance Raman study of Bacillus subtilis NO synthase-like protein: similarities and differences with mammalian NO synthases.
Topics: Animals; Bacillus subtilis; Carbon Monoxide; Ferric Compounds; Ferrous Compounds; Heme; Mice; Nitric Oxide; Nitric Oxide Synthase; Recombinant Proteins; Sensitivity and Specificity; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Vibration | 2006 |
Heme oxygenase-1 protects tumor cells against photodynamic therapy-mediated cytotoxicity.
Topics: Animals; Carbon Monoxide; Chelating Agents; Dihematoporphyrin Ether; Heme; Heme Oxygenase-1; Humans; Iron; Mice; Neoplasms; Oligonucleotide Array Sequence Analysis; Oxygen; Photochemotherapy; Reactive Oxygen Species | 2006 |
Multiple active site conformers in the carbon monoxide complexes of trematode hemoglobins.
Topics: Amino Acid Sequence; Animals; Binding Sites; Carbon Monoxide; Carboxyhemoglobin; Heme; Hemoglobins; Hydrogen Bonding; Iron; Models, Molecular; Molecular Sequence Data; Oxygen; Oxyhemoglobins; Protein Conformation; Sequence Homology, Amino Acid; Spectrum Analysis, Raman; Trematoda; Tyrosine | 2006 |
Critical roles of Leu99 and Leu115 at the heme distal side in auto-oxidation and the redox potential of a heme-regulated phosphodiesterase from Escherichia coli.
Topics: Amino Acid Sequence; Carbon Monoxide; Escherichia coli; Ferric Compounds; Ferrous Compounds; Heme; Heme Oxygenase-1; Hydrophobic and Hydrophilic Interactions; Iron; Leucine; Molecular Sequence Data; Molecular Structure; Mutation; Nitric Oxide; Oxidation-Reduction; Oxygen; Phosphoric Diester Hydrolases; Photolysis; Protein Binding | 2006 |
Thermodynamics of carbon monoxide photodissociation from the fully reduced cytochrome aa3 oxidase from Rb. sphaeroides.
Topics: Animals; Carbon Monoxide; Cattle; Electron Transport Complex IV; Escherichia coli; Heme; Molecular Conformation; Myocardium; Oxidation-Reduction; Photobiology; Photolysis; Rhodobacter sphaeroides; Temperature; Thermodynamics | 2006 |
Extended subnanosecond structural dynamics of myoglobin revealed by Laue crystallography.
Topics: Carbon Monoxide; Crystallography, X-Ray; Heme; Models, Molecular; Myoglobin; Protein Structure, Tertiary; Time Factors | 2006 |
Differential effects of alkyl- and arylguanidines on the stability and reactivity of inducible NOS heme-dioxygen complexes.
Topics: Animals; Carbon Monoxide; Enzyme Stability; Guanidine; Heme; Mice; Nitric Oxide Synthase Type II; Oxygen; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2006 |
Heterologous overexpression and purification of cytochrome c' from Rhodobacter capsulatus and a mutant (K42E) in the dimerization region. Mutation does not alter oligomerization but impacts the heme iron spin state and nitric oxide binding properties.
Topics: Carbon Monoxide; Cytochromes c'; Electron Spin Resonance Spectroscopy; Heme; Iron; Mutagenesis, Site-Directed; Nitric Oxide; Protein Structure, Quaternary; Rhodobacter capsulatus; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman | 2006 |
Raman evidence for specific substrate-induced structural changes in the heme pocket of human cytochrome P450 aromatase during the three consecutive oxygen activation steps.
Topics: Androstenedione; Aromatase; Carbon Monoxide; Ferrous Compounds; Heme; Humans; Models, Chemical; Oxygen; Spectrophotometry; Spectrum Analysis, Raman | 2006 |
Role of distal arginine in early sensing intermediates in the heme domain of the oxygen sensor FixL.
Topics: Arginine; Bacterial Proteins; Carbon Monoxide; Heme; Hemeproteins; Histidine Kinase; Hydrogen Bonding; Kinetics; Oxygen; Spectrum Analysis | 2006 |
Modeling proline ligation in the heme-dependent CO sensor, CooA, using small-molecule analogs.
Topics: Bacterial Proteins; Carbon Monoxide; Computational Biology; Crystallography, X-Ray; Heme; Hemeproteins; Histidine; Imidazoles; Iron; Ligands; Models, Molecular; Molecular Structure; Proline; Pyrrolidines; Trans-Activators | 2006 |
Carbon monoxide and biliverdin prevent endothelial cell sloughing in rats with type I diabetes.
Topics: Animals; Biliverdine; Carbon Monoxide; Cell Aggregation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Dinoprost; Endothelial Cells; Endothelium, Vascular; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Organometallic Compounds; Protective Agents; Rats | 2006 |
Time-dependent atomic coordinates for the dissociation of carbon monoxide from myoglobin.
Topics: Algorithms; Animals; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Heme; Models, Molecular; Mutation; Myoglobin; Photolysis; Protein Binding; Protein Conformation; Sperm Whale; Time Factors | 2006 |
The contribution of hemolysis to early jaundice in normal newborns.
Topics: Bilirubin; Birth Weight; Carbon Monoxide; Female; Gestational Age; Heme; Hemolysis; Humans; Infant, Newborn; Jaundice, Neonatal; Male | 2006 |
Extensive misfolding in the refolding reaction of alkaline ferrocytochrome C.
Topics: Animals; Carbon Monoxide; Cytochromes c; Heme; Horses; Hydrogen; Magnetic Resonance Spectroscopy; Protein Denaturation; Protein Folding; Sulfates | 2006 |
Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions.
Topics: Amino Acid Sequence; Bacterial Proteins; Carbon Monoxide; Cytochrome P-450 Enzyme System; Ferredoxins; Heme; Hydrogen-Ion Concentration; Iron; Kinetics; Molecular Sequence Data; Mycobacterium tuberculosis; Oxidation-Reduction; Oxidoreductases; Potentiometry; Spectrum Analysis; Sterol 14-Demethylase | 2006 |
Carbon monoxide: from the origin of life to molecular medicine.
Topics: Animals; Anti-Inflammatory Agents; Biliverdine; Carbon Monoxide; Colitis; Ferritins; Heme; Heme Oxygenase-1; Humans; Models, Biological | 2006 |
Molecular dynamics assignment of NMR correlation times to specific motions in a "basket-handle porphyrin" heme.
Topics: Anisotropy; Binding Sites; Carbon Monoxide; Heme; Iron; Kinetics; Ligands; Magnetic Resonance Spectroscopy; Models, Chemical; Molecular Conformation; Oxygen; Porphyrins; Solvents; Spectrometry, Fluorescence; Temperature | 2005 |
Quantum chemical evaluation of protein control over heme ligation: CO/O2 discrimination in myoglobin.
Topics: Animals; Binding Sites; Carbon; Carbon Monoxide; Heme; Histidine; Isoleucine; Models, Molecular; Molecular Conformation; Myoglobin; Oxygen; Photochemistry; Protein Binding; Quantum Theory; Software | 2005 |
Excited state property of hardly photodissociable heme-CO adduct studied by time-dependent density functional theory.
Topics: Carbon Monoxide; Electrons; Heme; Imidazoles; Iron; Ligands; Models, Molecular; Photolysis; Spectrum Analysis, Raman; Water | 2005 |
Effect of mutation on the dissociation and recombination dynamics of CO in transcriptional regulator CooA: a picosecond infrared transient absorption study.
Topics: Bacterial Proteins; Carbon Monoxide; Glycine; Heme; Hemeproteins; Histidine; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Recombination, Genetic; Regulatory Elements, Transcriptional; Rhodospirillum rubrum; Spectroscopy, Near-Infrared; Trans-Activators | 2006 |
In situ surface-enhanced IR absorption spectroscopy on CO adducts of iron protoporphyrin IX self-assembled on a Au electrode.
Topics: Carbon Monoxide; Electrodes; Gold; Metal Nanoparticles; Protoporphyrins; Spectroscopy, Fourier Transform Infrared | 2006 |
Heme displacement mechanism of CooA activation: mutational and Raman spectroscopic evidence.
Topics: Bacterial Proteins; Carbon Monoxide; Crystallography, X-Ray; DNA; Heme; Hemeproteins; Ligands; Models, Molecular; Molecular Conformation; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Spectrum Analysis, Raman; Trans-Activators | 2006 |
Role of phenylalanine B10 in plant nonsymbiotic hemoglobins.
Topics: Animals; Azides; Carbon Monoxide; Crystallography, X-Ray; Heme; Hemoglobins; Iron; Ligands; Models, Molecular; Mutant Proteins; Oryza; Oxidation-Reduction; Oxygen; Phenylalanine; Potentiometry; Protein Binding; Spectroscopy, Fourier Transform Infrared; Symbiosis | 2006 |
Coordination of diatomic ligands to heme: simply CO.
Topics: Carbon Monoxide; Crystallography, X-Ray; Heme; Ligands; Models, Molecular; Molecular Structure | 2006 |
Role of the locus coeruleus carbon monoxide pathway in endotoxin fever in rats.
Topics: Animals; Body Temperature; Carbon Monoxide; Central Nervous System; Cyclic GMP; Enzyme Inhibitors; Fever; Guanylate Cyclase; Heme; Heme Oxygenase (Decyclizing); Lipopolysaccharides; Locus Coeruleus; Lysine; Male; Rats; Rats, Wistar; Signal Transduction | 2007 |
Infrared absorption study of the heme pocket dynamics of carbonmonoxyheme proteins.
Topics: Carbon; Carbon Monoxide; Heme; Hemeproteins; Horseradish Peroxidase; Hydrogen-Ion Concentration; Models, Chemical; Myoglobin; Normal Distribution; Protein Binding; Protein Conformation; Solvents; Spectrophotometry, Infrared; Temperature; Trehalose | 2006 |
Structure of the Escherichia coli O157:H7 heme oxygenase ChuS in complex with heme and enzymatic inactivation by mutation of the heme coordinating residue His-193.
Topics: Alanine; Carbon Monoxide; Catalysis; Chromatography, Gas; Crystallography, X-Ray; Escherichia coli O157; Escherichia coli Proteins; Heme; Heme Oxygenase (Decyclizing); Histidine; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; X-Ray Diffraction | 2006 |
CD163-Mediated hemoglobin-heme uptake activates macrophage HO-1, providing an antiinflammatory function.
Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Bilirubin; Carbon Monoxide; Cytoprotection; Endocytosis; Ferritins; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase-1; Hemoglobins; Humans; Inflammation Mediators; Macrophages; Models, Biological; Receptors, Cell Surface; Transcription, Genetic | 2006 |
Spectroscopic characterization of a higher plant heme oxygenase isoform-1 from Glycine max (soybean)--coordination structure of the heme complex and catabolism of heme.
Topics: Amino Acid Sequence; Bilirubin; Binding Sites; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Glycine max; Heme; Heme Oxygenase-1; Ligands; Molecular Sequence Data; Plant Proteins; Sequence Alignment | 2006 |
DNA binding by an imidazole-sensing CooA variant is dependent on the heme redox state.
Topics: Bacterial Proteins; Carbon Monoxide; Circular Dichroism; DNA-Binding Proteins; Gene Expression Regulation, Bacterial; Heme; Hemeproteins; Histidine; Imidazoles; Oxidation-Reduction; Rhodospirillum rubrum; Trans-Activators | 2007 |
Ligand dynamics in an electron transfer protein. Picosecond geminate recombination of carbon monoxide to heme in mutant forms of cytochrome c.
Topics: Carbon Monoxide; Cytochromes c; Electrons; Heme; Kinetics; Ligands; Models, Chemical; Mutagenesis, Site-Directed; Mutation; Myoglobin; Nitric Oxide; Oxidation-Reduction; Oxygen; Protein Binding; Saccharomyces cerevisiae | 2007 |
Characterization of carbon monoxide photodissociation from Fe(II)LPO with photoacoustic calorimetry.
Topics: Animals; Arginine; Binding Sites; Calorimetry; Carbon Monoxide; Cattle; Ferrous Compounds; Heme; Hydrogen-Ion Concentration; Lactoperoxidase; Milk; Photolysis; Propionates; Protein Conformation; Sodium Chloride; Thermodynamics | 2006 |
Time-resolved methods in Biophysics. 2. Monitoring haem proteins at work with nanosecond laser flash photolysis.
Topics: Arabidopsis; Biophysics; Carbon Monoxide; Heme; Hemoglobins; Kinetics; Lasers; Photolysis; Time Factors | 2006 |
Differential sensing of protein influences by NO and CO vibrations in heme adducts.
Topics: Binding Sites; Carbon Monoxide; Electrons; Ferric Compounds; Heme; Hemeproteins; Ligands; Models, Chemical; Nitric Oxide; Porphyrins; Sensitivity and Specificity; Spectrum Analysis, Raman; Vibration | 2006 |
Role of the peripheral heme oxygenase-carbon monoxide pathway on the nociceptive response of rats to the formalin test: evidence for a cGMP signaling pathway.
Topics: Animals; Biliverdine; Carbon Monoxide; Cyclic GMP; Deferoxamine; Deuteroporphyrins; Heme; Heme Oxygenase (Decyclizing); Iron Chelating Agents; Lysine; Male; Pain; Pain Measurement; Rats; Rats, Wistar; Signal Transduction | 2007 |
Electron transfer and ligand binding to cytochrome c' immobilized on self-assembled monolayers.
Topics: Adsorption; Animals; Carbon Monoxide; Carboxylic Acids; Cytochromes c; Electrochemistry; Electrons; Gold; Heme; Horses; Hydrogen-Ion Concentration; Myocardium; Proteobacteria; Static Electricity; Sulfhydryl Compounds | 2007 |
NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism.
Topics: Amino Acid Sequence; Anabaena; Animals; Carbon Monoxide; Chlorocebus aethiops; COS Cells; Enzyme Activation; Guanylate Cyclase; Heme; Models, Molecular; Molecular Sequence Data; Mutation; Nitric Oxide; Protein Binding; Protein Conformation; Receptors, Cytoplasmic and Nuclear; Sequence Homology, Amino Acid; Soluble Guanylyl Cyclase; Substrate Specificity | 2007 |
Theoretical density functional theory studies on interactions of small biologically active molecules with isolated heme group.
Topics: Carbon Monoxide; Computational Biology; Ferrous Compounds; Heme; Histidine; Ligands; Models, Molecular; Molecular Conformation; Nitric Oxide; Nitrogen Dioxide; Water | 2007 |
Heme oxygenase-1: a multifaceted triple-threat molecule.
Topics: Bilirubin; Carbon Monoxide; Gene Expression Regulation; Heme; Heme Oxygenase-1; Humans | 2007 |
Covalent heme attachment in Synechocystis hemoglobin is required to prevent ferrous heme dissociation.
Topics: Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Cyanides; Guanidine; Heme; Hemoglobins; Histidine; Iron; Ligands; Protein Binding; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Synechocystis | 2007 |
Spin-forbidden ligand binding to the ferrous-heme group: ab initio and DFT studies.
Topics: Calibration; Carbon Monoxide; Chemistry, Physical; Electron Spin Resonance Spectroscopy; Heme; Iron; Ligands; Models, Molecular; Models, Theoretical; Molecular Conformation; Nitric Oxide; Oxygen; Spin Labels | 2007 |
Anisotropic structural relaxation and its correlation with the excess energy diffusion in the incipient process of photodissociated MbCO: high-resolution analysis via ensemble perturbation method.
Topics: Animals; Anisotropy; Carbon Monoxide; Diffusion; Heme; Ligands; Models, Molecular; Models, Statistical; Molecular Conformation; Myoglobin; Protein Conformation; Thermodynamics; Time Factors | 2007 |
Redox control of fast ligand dissociation from Escherichia coli cytochrome bd.
Topics: Carbon Monoxide; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Kinetics; Ligands; Nitric Oxide; Oxidation-Reduction; Oxidoreductases; Oxygen Consumption; Protein Binding; Recombinant Proteins | 2007 |
Crystal structure of CO-sensing transcription activator CooA bound to exogenous ligand imidazole.
Topics: Bacterial Proteins; Carbon Monoxide; Crystallography, X-Ray; Heme; Imidazoles; Ligands; Models, Molecular; Peptococcaceae; Protein Conformation; Protein Structure, Quaternary; Trans-Activators | 2007 |
An IR study of protonation changes associated with heme-heme electron transfer in bovine cytochrome c oxidase.
Topics: Animals; Arginine; Carbon Monoxide; Cattle; Electron Transport; Electron Transport Complex IV; Heme; Hydrogen-Ion Concentration; Molecular Structure; Photolysis; Protons; Spectrophotometry, Infrared | 2007 |
Ultraviolet resonance Raman evidence for utilization of the heme 6-propionate hydrogen-bond network in signal transmission from heme to protein in Ec DOS protein.
Topics: Carbon Monoxide; Carrier Proteins; Crystallography, X-Ray; Escherichia coli Proteins; Heme; Hydrogen Bonding; Ligands; Models, Molecular; Mutation; Oxygen; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; Spectrum Analysis, Raman; Trypsin; Ultraviolet Rays | 2007 |
Structural and functional properties of a truncated hemoglobin from a food-borne pathogen Campylobacter jejuni.
Topics: Amino Acids; Bacterial Proteins; Binding Sites; Campylobacter Infections; Campylobacter jejuni; Carbon Monoxide; Cytochrome-c Peroxidase; Food Microbiology; Heme; Hemoglobins; Models, Molecular; Nitric Oxide; Oxygen; Spectrum Analysis, Raman; Structural Homology, Protein; Truncated Hemoglobins | 2007 |
Time-resolved crystallographic studies of the heme domain of the oxygen sensor FixL: structural dynamics of ligand rebinding and their relation to signal transduction.
Topics: Bacterial Proteins; Bradyrhizobium; Carbon Monoxide; Crystallization; Crystallography, X-Ray; Heme; Hemeproteins; Histidine Kinase; Ligands; Models, Molecular; Protein Kinases; Protein Structure, Tertiary; Signal Transduction | 2007 |
*NO dissociation represents the rate limiting step for O2-mediated oxidation of ferrous nitrosylated Mycobacterium leprae truncated hemoglobin O.
Topics: Bacterial Proteins; Carbon Monoxide; Ferrous Compounds; Heme; Hemoglobins; Kinetics; Models, Chemical; Nitric Oxide; Oxidation-Reduction; Oxygen; Recombinant Proteins; Truncated Hemoglobins | 2007 |
The formation of hydrogen bond in the proximal heme pocket of HemAT-Bs upon ligand binding.
Topics: Bacterial Proteins; Binding Sites; Carbon Monoxide; Computer Simulation; Heme; Heme-Binding Proteins; Hemeproteins; Hydrogen Bonding; Ligands; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation | 2007 |
Laser photoexcitation of NAD(P)H induces reduction of P450 BM3 heme domain on the microsecond time scale.
Topics: Alanine; Carbon Monoxide; Coenzymes; Cytochrome P-450 Enzyme System; Heme; Iron; Kinetics; Lasers; Mutation; NAD; Oxidation-Reduction; Photochemistry; Protein Binding; Spectrophotometry; Substrate Specificity; Time Factors | 2007 |
Resonance Raman observation of the structural dynamics of FixL on signal transduction and ligand discrimination.
Topics: Bacterial Proteins; Carbon Monoxide; Heme; Hemeproteins; Histidine Kinase; Ligands; Oxygen; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Protein Structure, Tertiary; Signal Transduction; Sinorhizobium meliloti; Spectrum Analysis, Raman; Thermodynamics | 2007 |
Heme oxygenase-1 and carbon monoxide suppress the pathogenesis of experimental cerebral malaria.
Topics: Animals; Carbon Monoxide; Disease Models, Animal; Heme; Heme Oxygenase-1; Malaria, Cerebral; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Mice, SCID; Plasmodium berghei | 2007 |
The contribution of heme propionate groups to the conformational dynamics associated with CO photodissociation from horse heart myoglobin.
Topics: Animals; Calorimetry; Carbon Monoxide; Heme; Horses; Models, Molecular; Molecular Structure; Myoglobin; Photochemistry; Propionates; Protein Binding; Protein Conformation | 2007 |
Interdiction of the diabetic state in NOD mice by sustained induction of heme oxygenase: possible role of carbon monoxide and bilirubin.
Topics: Animals; bcl-X Protein; Bilirubin; Blood Glucose; Blotting, Western; Carbon Monoxide; CD11 Antigens; Dendritic Cells; Diabetes Mellitus, Type 1; Enzyme Activation; Female; Glucagon; Heme; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Immunohistochemistry; Insulin; Insulin-Secreting Cells; Mice; Mice, Inbred NOD; NADPH Oxidases; Pancreas; Proto-Oncogene Proteins c-akt; Protoporphyrins | 2007 |
Transient ligand docking sites in Cerebratulus lacteus mini-hemoglobin.
Topics: Amino Acid Substitution; Amino Acids; Animals; Binding Sites; Carbon Monoxide; Heme; Hemoglobins; Hydrogen Bonding; Invertebrates; Kinetics; Ligands; Models, Molecular; Mutation; Oxygen; Oxyhemoglobins; Protein Binding; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Temperature; Thermodynamics | 2007 |
Critical role of the heme axial ligand, Met95, in locking catalysis of the phosphodiesterase from Escherichia coli (Ec DOS) toward Cyclic diGMP.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Carbon Monoxide; Catalysis; Cyclic GMP; Escherichia coli; Heme; Iron; Ligands; Methionine; Models, Molecular; Nitric Oxide; Oxygen; Phosphoric Diester Hydrolases; Protein Binding; Protein Conformation | 2007 |
Ligand-induced monomerization of Allochromatium vinosum cytochrome c' studied using native mass spectrometry and fluorescence resonance energy transfer.
Topics: Binding Sites; Carbon Monoxide; Cyanides; Cytochromes c'; Dimerization; Fluorescence Resonance Energy Transfer; Heme; Kinetics; Ligands; Mass Spectrometry; Nitric Oxide; Protein Conformation | 2007 |
Simulation of heme using DFT + U: a step toward accurate spin-state energetics.
Topics: Carbon Monoxide; Computer Simulation; Electrons; Heme; Iron; Ligands; Models, Biological; Models, Molecular; Molecular Conformation; Oxygen; Porphyrins; Quantum Theory | 2007 |
Rapid P450 heme iron reduction by laser photoexcitation of Mycobacterium tuberculosis CYP121 and CYP51B1. Analysis of CO complexation reactions and reversibility of the P450/P420 equilibrium.
Topics: Bacterial Proteins; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Gene Expression Regulation, Bacterial; Heme; Hydrogen-Ion Concentration; Iron; Kinetics; Lasers; Models, Chemical; Mycobacterium tuberculosis; Photochemistry; Sulfhydryl Compounds; Time Factors | 2007 |
Heme moves to center stage in cerebral malaria.
Topics: Animals; Carbon Monoxide; Disease Models, Animal; Heme; Heme Oxygenase-1; Malaria, Cerebral; Mice | 2007 |
Different roles of protein dynamics and ligand migration in non-symbiotic hemoglobins AHb1 and AHb2 from Arabidopsis thaliana.
Topics: Arabidopsis Proteins; Binding Sites; Carbon Monoxide; Gels; Glycerol; Heme; Hemoglobins; Kinetics; Ligands; Models, Chemical; Photolysis; Protein Binding; Silicon Dioxide; Solutions; Spectrophotometry; Temperature | 2007 |
DosT and DevS are oxygen-switched kinases in Mycobacterium tuberculosis.
Topics: Adenosine Triphosphate; Bacterial Proteins; Binding Sites; Carbon Monoxide; Cations, Divalent; Heme; Kinetics; Ligands; Models, Biological; Mycobacterium tuberculosis; Nitric Oxide; Oxidation-Reduction; Oxygen; Protamine Kinase; Protein Kinases; Protein Structure, Tertiary | 2007 |
Reactivity studies on Fe(III)-(O2(2-))-Cu(II) compounds: influence of the ligand architecture and copper ligand denticity.
Topics: Acids; Carbon Monoxide; Chemistry, Inorganic; Copper; Heme; Iron; Ligands; Models, Chemical; Oxygen; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman | 2007 |
Myocardial cytochrome oxidase activity is decreased following carbon monoxide exposure.
Topics: Animals; Carbon Monoxide; Carboxyhemoglobin; Electron Transport Complex IV; Gene Expression Regulation; Heart; Heme; Hypoxia; Male; Mice; Mice, Inbred C57BL; Myocardium; RNA, Messenger | 2007 |
Structure and ligand binding properties of myoglobins reconstituted with monodepropionated heme: functional role of each heme propionate side chain.
Topics: Amino Acid Sequence; Animals; Carbon Monoxide; Crystallography, X-Ray; Heme; Iron; Ligands; Metmyoglobin; Molecular Sequence Data; Myoglobin; Oxidation-Reduction; Oxygen; Propionates; Protein Conformation; Spectrum Analysis, Raman | 2007 |
Probing the environment of cu(b) in heme-copper oxidases.
Topics: Binding Sites; Carbon Monoxide; Copper; Electron Transport Complex IV; Heme; Models, Chemical; Models, Molecular; Nickel; Photolysis; Pseudomonas stutzeri; Spectroscopy, Fourier Transform Infrared | 2007 |
The heme pocket geometry of Lucina pectinata hemoglobin II restricts nitric oxide and peroxide entry: model of ligand control for the design of a stable oxygen carrier.
Topics: Animals; Bivalvia; Carbon Monoxide; Heme; Hemoglobins; Humans; Iron; Kinetics; Ligands; Mass Spectrometry; Methemoglobin; Mutant Proteins; Nitric Oxide; Oxidation-Reduction; Oxygen; Oxyhemoglobins; Peroxides; Stereoisomerism | 2007 |
Mechanism of the CO-sensing heme protein CooA: new insights from the truncated heme domain and UVRR spectroscopy.
Topics: Bacterial Proteins; Binding Sites; Carbon Monoxide; Heme; Hemeproteins; Models, Molecular; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman | 2007 |
Evidence for fast conformational change upon ligand dissociation in the HemAT class of bacterial oxygen sensors.
Topics: Bacterial Proteins; Calorimetry; Carbon Monoxide; Heme; Hemeproteins; Ligands; Models, Molecular; Oxygen; Protein Binding; Protein Conformation; Thermodynamics | 2007 |
Temperature-dependent heme kinetics with nonexponential binding and barrier relaxation in the absence of protein conformational substates.
Topics: Binding Sites; Carbon Monoxide; Heme; Hemeproteins; Kinetics; Ligands; Mathematics; Myoglobin; Nitric Oxide; Photolysis; Protein Binding; Protein Conformation; Spectrophotometry, Infrared; Temperature; Thermodynamics | 2007 |
Carbon monoxide can prevent acute lung injury observed after ischemia reperfusion of the lower extremities.
Topics: Animals; Anti-Inflammatory Agents; Antimetabolites; Bilirubin; Blood Pressure; Carbon Monoxide; Coloring Agents; Disease Models, Animal; Drug Therapy, Combination; Evans Blue; Heme; Hindlimb; Male; Pulmonary Edema; Rats; Rats, Wistar; Reperfusion Injury; Respiratory Distress Syndrome; Severity of Illness Index | 2007 |
Effect of strain in the proximal ligand on the binding of nitric oxide and carbon monoxide to chelated protoheme complexes.
Topics: Carbon Monoxide; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Heme; Histidine; Imidazoles; Iron; Ligands; Methanol; Models, Chemical; Molecular Structure; Nitric Oxide; Stress, Mechanical; Thermodynamics | 2007 |
Direct observation of ligand transfer and bond formation in cytochrome c oxidase by using mid-infrared chirped-pulse upconversion.
Topics: Binding Sites; Carbon Monoxide; Computer Simulation; Deuterium Oxide; Electrochemistry; Electron Transport Complex IV; Heme; Hydrogen Bonding; Kinetics; Ligands; Protein Binding; Spectrophotometry, Infrared | 2007 |
Evidence for a possible inhibitory interaction between the HO-1/CO- and Akt/NO-pathways in human endothelial cells.
Topics: Carbon Monoxide; Cell Proliferation; Cells, Cultured; DNA; Down-Regulation; Endothelial Cells; Enzyme Activation; Genetic Vectors; Green Fluorescent Proteins; Heme; Heme Oxygenase-1; Humans; Hydrogen Peroxide; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Retroviridae; Virus Replication | 2007 |
Peroxynitrite inactivation of human cytochrome P450s 2B6 and 2E1: heme modification and site-specific nitrotyrosine formation.
Topics: Amino Acid Sequence; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Enzyme Inhibitors; Heme; Humans; Models, Molecular; Molecular Sequence Data; Oxidoreductases, N-Demethylating; Peroxynitrous Acid; tert-Butylhydroperoxide; Tyrosine | 2007 |
Ligand migration in nonsymbiotic hemoglobin AHb1 from Arabidopsis thaliana.
Topics: Arabidopsis; Arabidopsis Proteins; Carbon Monoxide; Gels; Glycerol; Heme; Hemoglobins; Kinetics; Lasers; Ligands; Models, Molecular; Photolysis; Protein Binding; Silicon Dioxide | 2007 |
Flash-photolysis of fully reduced and mixed-valence CO-bound Rhodobacter sphaeroides cytochrome c oxidase: heme spectral shifts.
Topics: Carbon Monoxide; Electron Transport Complex IV; Heme; Oxidation-Reduction; Photolysis; Rhodobacter sphaeroides; Spectrum Analysis; Time Factors | 2007 |
A quantum-chemical picture of hemoglobin affinity.
Topics: Allosteric Regulation; Carbon Monoxide; Heme; Hemoglobins; Iron; Models, Molecular; Protein Structure, Secondary; Protein Structure, Tertiary | 2007 |
A comparative study of O2, CO and CN binding to heme IX protein models.
Topics: Carbon Monoxide; Cyanides; Heme; Hemeproteins; Iron; Ligands; Models, Molecular; Oxygen; Oxyhemoglobins; Porphyrins | 2004 |
Role of the spinal cord heme oxygenase-carbon monoxide-cGMP pathway in the nociceptive response of rats.
Topics: Animals; Carbon Monoxide; Cyclic GMP; Deuteroporphyrins; Heme; Heme Oxygenase (Decyclizing); Lysine; Male; Methylene Blue; Pain; Rats; Rats, Sprague-Dawley; Spinal Cord | 2008 |
Unusually strong H-bonding to the heme ligand and fast geminate recombination dynamics of the carbon monoxide complex of Bacillus subtilis truncated hemoglobin.
Topics: Bacillus subtilis; Carbon Monoxide; Heme; Hydrogen Bonding; Kinetics; Lasers; Models, Molecular; Mutation; Photolysis; Protein Binding; Recombinant Proteins; Spectrophotometry; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Truncated Hemoglobins | 2008 |
BYK191023 (2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3h-imidazo[4,5-b]pyridine) is an NADPH- and time-dependent irreversible inhibitor of inducible nitric-oxide synthase.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Cell Line; Chromatography, Gel; Chromatography, High Pressure Liquid; Dimerization; Enzyme Activation; Enzyme Inhibitors; Heme; Humans; Imidazoles; Iron; Kinetics; Mice; NADP; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxygen; Pyridines; Time Factors; Tritium | 2008 |
Archaeal protoglobin structure indicates new ligand diffusion paths and modulation of haem-reactivity.
Topics: Archaeal Proteins; Carbon Monoxide; Crystallography, X-Ray; Diffusion; Heme; Kinetics; Ligands; Methanosarcina; Models, Molecular; Oxygen; Protein Structure, Secondary; Thermodynamics | 2008 |
Carbon monoxide reversibly alters iron homeostasis and respiratory epithelial cell function.
Topics: Acetaldehyde; Animals; Antimetabolites; Antioxidants; Bronchoalveolar Lavage; Carbon Monoxide; Cell Line; Cell Proliferation; Child; Deferoxamine; Epithelial Cells; Ferritins; Heme; Homeostasis; Humans; Interleukin-8; Iron; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Respiratory Mucosa; Siderophores | 2008 |
Novel heme ligand displacement by CO in the soluble hemophore HasA and its proximal ligand mutants: implications for heme uptake and release.
Topics: Carbon Monoxide; Heme; Hydrogen Bonding; Ligands; Models, Molecular; Molecular Probes; Mutation; Oxidation-Reduction; Spectrum Analysis, Raman | 2008 |
Interaction of bd-type quinol oxidase from Escherichia coli and carbon monoxide: heme d binds CO with high affinity.
Topics: Carbon Monoxide; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Escherichia coli Proteins; Heme; Membrane Proteins; Oxidation-Reduction; Oxidoreductases; Spectrophotometry | 2008 |
RcoM: a new single-component transcriptional regulator of CO metabolism in bacteria.
Topics: Aerobiosis; Amino Acid Sequence; Bacterial Proteins; Burkholderia; Carbon Monoxide; Escherichia coli; Gene Expression Regulation, Bacterial; Genome, Bacterial; Genomics; Heme; Ligands; Molecular Sequence Data; Nitric Oxide; Oxidation-Reduction; Oxygen; Protein Structure, Tertiary; Regulon; Transcription Factors | 2008 |
Structures and solution properties of two novel periplasmic sensor domains with c-type heme from chemotaxis proteins of Geobacter sulfurreducens: implications for signal transduction.
Topics: Bacterial Proteins; Carbon Monoxide; Chemotaxis; Chromatography, Gel; Circular Dichroism; Crystallography, X-Ray; Dimerization; Electron Spin Resonance Spectroscopy; Geobacter; Heme; Hydrogen-Ion Concentration; Imidazoles; Magnetic Resonance Spectroscopy; Nitric Oxide; Oxidation-Reduction; Protein Binding; Protein Structure, Tertiary; Signal Transduction | 2008 |
Role of locus coeruleus heme oxygenase-carbon monoxide-cGMP pathway during hypothermic response to restraint.
Topics: Animals; Behavior, Animal; Body Temperature; Carbon Monoxide; Cyclic GMP; Deuteroporphyrins; Enzyme Inhibitors; Heme; Heme Oxygenase (Decyclizing); Hypothermia; Locus Coeruleus; Lysine; Male; Microinjections; Rats; Rats, Wistar; Restraint, Physical | 2008 |
An X-ray diffraction and X-ray absorption spectroscopy joint study of neuroglobin.
Topics: Animals; Carbon Monoxide; Cloning, Molecular; Escherichia coli; Globins; Heme; Histidine; Iron; Mice; Nerve Tissue Proteins; Neuroglobin; Oxidation-Reduction; Protein Binding; Recombinant Proteins; Spectrum Analysis; X-Ray Diffraction; X-Rays | 2008 |
NO sensing in Pseudomonas aeruginosa: structure of the transcriptional regulator DNR.
Topics: Amino Acid Sequence; Bacterial Proteins; Carbon Monoxide; Crystallography, X-Ray; Dimerization; DNA; Gene Expression Regulation, Bacterial; Heme; Humans; Molecular Sequence Data; Nitric Oxide; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Pseudomonas aeruginosa; Sequence Alignment; Transcription Factors; Transcription, Genetic | 2008 |
Roles of Arg-97 and Phe-113 in regulation of distal ligand binding to heme in the sensor domain of Ec DOS protein. Resonance Raman and mutation study.
Topics: Amino Acid Substitution; Arginine; Carbon Monoxide; Carrier Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Hydrogen Bonding; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation, Missense; Nitric Oxide; Phenylalanine; Phosphoric Diester Hydrolases; Protein Structure, Tertiary; Spectrum Analysis, Raman | 2008 |
Isoporphyrin intermediate in heme oxygenase catalysis. Oxidation of alpha-meso-phenylheme.
Topics: Biliverdine; Carbon Monoxide; Catalysis; Chromatography, High Pressure Liquid; Heme; Heme Oxygenase-1; Humans; Hydrogen Peroxide; Iron; NADP; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Superoxides | 2008 |
How CO binds to hexacoordinated heme in neuroglobin protein.
Topics: Binding Sites; Carbon Monoxide; Globins; Heme; Models, Molecular; Nerve Tissue Proteins; Neuroglobin; Quantum Theory; Thermodynamics | 2008 |
Glutamate 107 in subunit I of cytochrome bd from Escherichia coli is part of a transmembrane intraprotein pathway conducting protons from the cytoplasm to the heme b595/heme d active site.
Topics: Binding Sites; Carbon Monoxide; Cytochrome b Group; Cytochromes; Cytoplasm; Electrochemistry; Electron Transport Chain Complex Proteins; Escherichia coli Proteins; Glutamic Acid; Heme; Leucine; Mutagenesis, Site-Directed; Mutation; Oxidoreductases; Photolysis; Protein Binding; Protons | 2008 |
Interaction of nitric oxide with a functional model of cytochrome c oxidase.
Topics: Carbon Monoxide; Catalytic Domain; Copper; Cyanides; Electron Spin Resonance Spectroscopy; Electron Transport; Electron Transport Complex IV; Heme; Models, Biological; Models, Molecular; Nitric Oxide; Spectrophotometry | 2008 |
Ex vivo carbon monoxide prevents cytochrome P450 degradation and ischemia/reperfusion injury of kidney grafts.
Topics: Animals; Carbon Monoxide; Cryopreservation; Cytochrome P-450 Enzyme System; Heme; Inflammation Mediators; Kidney Transplantation; Lipid Peroxidation; Organ Preservation; Organ Preservation Solutions; Rats; Rats, Inbred Lew; Reperfusion Injury | 2008 |
Arg97 at the heme-distal side of the isolated heme-bound PAS domain of a heme-based oxygen sensor from Escherichia coli (Ec DOS) plays critical roles in autoxidation and binding to gases, particularly O2.
Topics: Arginine; Carbon Monoxide; Carrier Proteins; Crystallography, X-Ray; Cyclic GMP; Escherichia coli Proteins; Ferric Compounds; Ferrous Compounds; Heme; Iron; Models, Molecular; Mutagenesis, Site-Directed; Nitric Oxide; Oxidation-Reduction; Oxygen; Phosphoric Diester Hydrolases; Protein Binding; Protein Structure, Tertiary; Structure-Activity Relationship | 2008 |
Binding of CO, NO, and O2 to heme by density functional and multireference ab initio calculations.
Topics: Carbon Monoxide; Electrons; Heme; Ligands; Myoglobin; Nitric Oxide; Oxygen; Quantum Theory; Thermodynamics | 2008 |
Changes in quaternary structure in the signaling mechanisms of PAS domains.
Topics: Bacterial Proteins; Bradyrhizobium; Carbon Monoxide; Coenzymes; Dimerization; Heme; Hemeproteins; Histidine Kinase; Nitrogen Fixation; Oxygen; Protein Kinases; Protein Structure, Quaternary; Protein Structure, Tertiary; Signal Transduction; Structure-Activity Relationship | 2008 |
Resonance Raman interrogation of the consequences of heme rotational disorder in myoglobin and its ligated derivatives.
Topics: Animals; Carbon Monoxide; Heme; Horses; Isomerism; Myoglobin; Nitriles; Propionates; Rotation; Spectrum Analysis, Raman | 2008 |
Dynamics of carbon monoxide photodissociation in Bradyrhizobium japonicum FixL probed by picosecond midinfrared spectroscopy.
Topics: Bradyrhizobium; Carbon Monoxide; Heme; Hot Temperature; Kinetics; Models, Molecular; Molecular Conformation; Photochemistry; Photolysis; Solvents; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Thermodynamics | 2009 |
The measurement of nitric oxide and its metabolites in biological samples by ozone-based chemiluminescence.
Topics: Body Fluids; Carbon Monoxide; Cell Extracts; Erythrocytes; Freezing; Heme; Hydrogen-Ion Concentration; Indicators and Reagents; Luminescent Measurements; Nitric Oxide; Nitrites; Ozone; Photolysis; Reference Standards; Time Factors | 2008 |
Heme oxygenase-1: from biology to therapeutic potential.
Topics: Animals; Bilirubin; Biliverdine; Carbon Monoxide; Disease; Enzyme Induction; Evolution, Molecular; Heme; Heme Oxygenase-1; Homeostasis; Humans; Models, Molecular; Protein Structure, Tertiary | 2009 |
Role of substrate functional groups in binding to nitric oxide synthase.
Topics: Arginine; Carbon Monoxide; Heme; Hydrogen Bonding; Ligands; Nitric Oxide Synthase Type II; Spectrum Analysis, Raman; Substrate Specificity | 2009 |
Linking conformation change to hemoglobin activation via chain-selective time-resolved resonance Raman spectroscopy of protoheme/mesoheme hybrids.
Topics: alpha-Globins; beta-Globins; Carbon Monoxide; Erythrocytes; Heme; Hemoglobin A; Humans; Mesoporphyrins; Photolysis; Protein Conformation; Spectrum Analysis, Raman | 2009 |
Molecular biosensor based on a coordinated iron complex.
Topics: Air Pollutants; Biosensing Techniques; Carbon Monoxide; Gases; Guanylate Cyclase; Heme; Models, Molecular; Nitric Oxide; Oxygen | 2009 |
Design and engineering of an O(2) transport protein.
Topics: Biological Transport; Carbon Monoxide; Carrier Proteins; Drug Design; Globins; Glutamic Acid; Heme; Histidine; Humans; Kinetics; Ligands; Nerve Tissue Proteins; Neuroglobin; Oxidation-Reduction; Oxygen; Protein Engineering; Protein Structure, Secondary; Rotation; Spectroscopy, Fourier Transform Infrared; Substrate Specificity; Water | 2009 |
Dipyridamole inhibits cobalt chloride-induced osteopontin expression in NRK52E cells.
Topics: Animals; Biocatalysis; Carbon Monoxide; Cell Line; Cobalt; Dipyridamole; Enzyme Induction; Epithelial Cells; Gene Expression Regulation; Heme; Heme Oxygenase-1; Kidney Tubules; Mitogen-Activated Protein Kinase Phosphatases; Osteopontin; Rats; Reactive Oxygen Species | 2009 |
The transcription factor DNR from Pseudomonas aeruginosa specifically requires nitric oxide and haem for the activation of a target promoter in Escherichia coli.
Topics: Bacterial Proteins; Base Sequence; Carbon Monoxide; Escherichia coli; Gene Expression Regulation, Bacterial; Genes, Bacterial; Genes, Reporter; Heme; Humans; Molecular Sequence Data; Nitric Oxide; Promoter Regions, Genetic; Pseudomonas aeruginosa; Pseudomonas Infections; Transcription Factors; Transcriptional Activation; Virulence | 2009 |
Is the redox state of the ci heme of the cytochrome b6f complex dependent on the occupation and structure of the Qi site and vice versa?
Topics: Aerobiosis; Amino Acid Substitution; Animals; Carbon Monoxide; Chlamydomonas reinhardtii; Cytochrome b6f Complex; Electricity; Electrons; Heme; Hydrogen-Ion Concentration; Kinetics; Light; Mutant Proteins; Mutation; Oxidation-Reduction; Photolysis; Protein Multimerization; Spectrum Analysis | 2009 |
Role of Phe113 at the distal side of the heme domain of an oxygen-sensor (Ec DOS) in the characterization of the heme environment.
Topics: Amino Acid Sequence; Carbon Monoxide; Crystallography, X-Ray; Cyanides; Escherichia coli; Escherichia coli Proteins; Heme; Molecular Sequence Data; Molecular Structure; Oxygen; Phenylalanine; Phosphoric Diester Hydrolases | 2009 |
CO photodissociation dynamics in cytochrome P450BM3 studied by subpicosecond visible and mid-infrared spectroscopy.
Topics: Bacillus megaterium; Bacterial Proteins; Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Iron; Kinetics; Models, Molecular; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Photochemical Processes; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis | 2009 |
Measurements of heme relaxation and ligand recombination in strong magnetic fields.
Topics: Animals; Carbon Monoxide; Ferrous Compounds; Heme; Horseradish Peroxidase; Horses; Ligands; Magnetics; Models, Molecular; Myoglobin; Nitrogen Oxides; Oxygen; Protein Binding | 2009 |
Guanidine hydrochloride-induced unfolding of the three heme coordination states of the CO-sensing transcription factor, CooA.
Topics: Bacterial Proteins; Biosensing Techniques; Carbon Monoxide; Circular Dichroism; DNA; Guanidine; Heme; Hemeproteins; Iron; Models, Molecular; Mutant Proteins; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Protein Structure, Tertiary; Spectrometry, Fluorescence; Thermodynamics; Trans-Activators; Transcription Factors | 2009 |
Characterization of the proximal ligand in the P420 form of inducible nitric oxide synthase.
Topics: Absorption; Animals; Carbon Monoxide; Heme; Hemin; Horses; Hydrogen-Ion Concentration; Isoenzymes; Ligands; Mice; Myoglobin; Nitric Oxide Synthase Type II; Oxygenases; Protein Structure, Tertiary; Protons; Spectrum Analysis, Raman; Sulfhydryl Compounds; Time Factors | 2009 |
Heme cavity dynamics of photodissociated CO from ba3-cytochrome c oxidase: the role of ring-D propionate.
Topics: Binding Sites; Carbon Monoxide; Copper; Cytochrome b Group; Electron Transport Complex IV; Heme; Models, Chemical; Models, Molecular; Molecular Conformation; Oxygen; Protein Binding; Protons; Spectrophotometry; Spectrophotometry, Infrared; Thermus thermophilus; Time Factors | 2009 |
Evidence of carbon monoxide-mediated phase advancement of the yeast metabolic cycle.
Topics: Blotting, Western; Carbon Monoxide; Chromatography, Liquid; Heme; Heme Oxygenase (Decyclizing); Mass Spectrometry; Metabolome; Metabolomics; Mutation; Oxidation-Reduction; Oxygen; Oxygen Consumption; Peroxidases; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Time Factors | 2009 |
The role of an amino acid triad at the entrance of the heme pocket in human serum albumin for O(2) and CO binding to iron protoporphyrin IX.
Topics: Amino Acids; Carbon Monoxide; Deuterium; Erythrocytes; Heme; Humans; Models, Molecular; Oxygen; Protein Conformation; Protoporphyrins; Recombinant Proteins; Serum Albumin; Spectrophotometry, Infrared; Spectrum Analysis, Raman | 2009 |
The FG loop of a heme-based gas sensor enzyme, Ec DOS, functions in heme binding, autoxidation and catalysis.
Topics: Amino Acid Substitution; Carbon Monoxide; Escherichia coli; Escherichia coli Proteins; Heme; Mutation, Missense; Oxidation-Reduction; Oxygen; Phosphoric Diester Hydrolases; Protein Structure, Secondary; Protein Structure, Tertiary | 2009 |
Carbon monoxide and nitrogen monoxide ligand dynamics in synthetic heme and heme-copper complex systems.
Topics: Carbon Monoxide; Copper; Crystallography, X-Ray; Heme; Kinetics; Ligands; Nitric Oxide; Photolysis; Spectrum Analysis | 2009 |
Characterization of heme coordination structure in heme-DNA complex possessing gaseous molecule as an exogenous ligand.
Topics: Carbon Monoxide; DNA; G-Quadruplexes; Gases; Heme; Ligands; Nuclear Magnetic Resonance, Biomolecular; Oxygen; Protoporphyrins; Spectrum Analysis | 2009 |
Ligand and substrate migration in human indoleamine 2,3-dioxygenase.
Topics: Binding Sites; Carbon Monoxide; Heme; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ligands; Photolysis; Protein Conformation; Recombinant Proteins; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Tryptophan | 2009 |
Interaction of artemisinins with oxyhemoglobin Hb-FeII, Hb-FeII, carboxyHb-FeII, heme-FeII, and carboxyheme FeII: significance for mode of action and implications for therapy of cerebral malaria.
Topics: Antimalarials; Artemisinins; Carbon Monoxide; Carboxyhemoglobin; Erythrocytes; Heme; Humans; Malaria, Cerebral; Molecular Structure; Oxyhemoglobins; Plasmodium falciparum | 2009 |
Heme ligand binding properties and intradimer interactions in the full-length sensor protein dos from Escherichia coli and its isolated heme domain.
Topics: Carbon Monoxide; Escherichia coli; Escherichia coli Proteins; Heme; Ligands; Oxygen; Phosphoric Diester Hydrolases; Protein Multimerization; Protein Structure, Quaternary; Protein Structure, Tertiary | 2009 |
A structural basis for H-NOX signaling in Shewanella oneidensis by trapping a histidine kinase inhibitory conformation.
Topics: Animals; Carbon Monoxide; Heme; Histidine Kinase; Molecular Structure; Nitric Oxide; Nuclear Magnetic Resonance, Biomolecular; Phosphorylation; Protein Conformation; Protein Kinases; Shewanella; Signal Transduction | 2009 |
CO binding and ligand discrimination in human myeloperoxidase.
Topics: Carbon Monoxide; Catalytic Domain; Heme; Humans; Iron; Ligands; Models, Molecular; Oxygen; Peroxidase; Protein Binding; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Substrate Specificity | 2010 |
Spectroscopic identification of heme axial ligands in HtsA that are involved in heme acquisition by Streptococcus pyogenes.
Topics: Bacterial Proteins; Carbon Monoxide; Carrier Proteins; Heme; Heme-Binding Proteins; Hemeproteins; Ligands; Mutation, Missense; Spectrum Analysis; Streptococcus pyogenes | 2010 |
P450cam visits an open conformation in the absence of substrate.
Topics: Camphor 5-Monooxygenase; Carbon Monoxide; Crystallography, X-Ray; Escherichia coli; Gene Expression Regulation, Enzymologic; Genetic Vectors; Heme; Hydrogen Bonding; Models, Molecular; Protein Conformation; Pseudomonas putida; Spectrophotometry; Substrate Specificity; Surface Properties | 2010 |
Fe-heme structure in Cu, Zn superoxide dismutase from Haemophilus ducreyi by X-ray absorption spectroscopy.
Topics: Carbon Monoxide; Copper; Ferric Compounds; Ferrous Compounds; Haemophilus ducreyi; Heme; Iron; Ligands; Models, Molecular; Nitric Oxide; Protein Conformation; Superoxide Dismutase; X-Ray Absorption Spectroscopy; Zinc | 2010 |
Probing soluble guanylate cyclase activation by CO and YC-1 using resonance Raman spectroscopy.
Topics: Animals; Binding Sites; Carbon Monoxide; Enzyme Activation; Guanylate Cyclase; Heme; Indazoles; Kinetics; Protein Binding; Protein Structure, Tertiary; Rats; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Spectrum Analysis, Raman | 2010 |
How active-site protonation state influences the reactivity and ligation of the heme in chlorite dismutase.
Topics: Biocatalysis; Carbon Monoxide; Catalytic Domain; Enzyme Stability; Heme; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kinetics; Ligands; Oxidoreductases; Protein Binding; Protons; Rhodocyclaceae; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman | 2010 |
Effect of heme modification on oxygen affinity of myoglobin and equilibrium of the acid-alkaline transition in metmyoglobin.
Topics: Acids; Alkalies; Carbon Monoxide; Electrons; Heme; Hydrogen-Ion Concentration; Metmyoglobin; Myoglobin; Nuclear Magnetic Resonance, Biomolecular; Oxygen | 2010 |
Identification of a thiol/disulfide redox switch in the human BK channel that controls its affinity for heme and CO.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Binding, Competitive; Carbon Monoxide; Cysteine; Disulfides; Electron Spin Resonance Spectroscopy; Electrophoresis, Polyacrylamide Gel; Ferric Compounds; Ferrous Compounds; Heme; Heme Oxygenase (Decyclizing); Humans; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Protein Binding; Sulfhydryl Compounds | 2010 |
Characterization of conformational changes and noncovalent complexes of myoglobin by electrospray ionization mass spectrometry, circular dichroism and fluorescence spectroscopy.
Topics: Acetonitriles; Animals; Benzenesulfonates; Carbon Monoxide; Circular Dichroism; Heme; Horses; Hydrogen-Ion Concentration; Methanol; Myoglobin; Protein Binding; Protein Conformation; Protein Denaturation; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Water | 2010 |
Heme-heme and heme-ligand interactions in the di-heme oxygen-reducing site of cytochrome bd from Escherichia coli revealed by nanosecond absorption spectroscopy.
Topics: Carbon Monoxide; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Ligands; Oxidation-Reduction; Oxidoreductases; Photolysis; Spectrum Analysis | 2010 |
Molecular insight into intrinsic heme distortion in ligand binding in hemoprotein.
Topics: Carbon Monoxide; Heme; Hemeproteins; Histidine; Iron; Ligands; Magnetic Resonance Spectroscopy; Myoglobin; Nitric Oxide; Oxygen; Water | 2010 |
[The anti-athetotic effects of heme-L-lysinate in a rabbit model of atherosclerosis].
Topics: Animals; Atherosclerosis; Carbon Monoxide; Cholesterol, Dietary; Diet, Atherogenic; Disease Models, Animal; Heme; Heme Oxygenase-1; HSC70 Heat-Shock Proteins; Lysine; Male; Rabbits; RNA, Messenger | 2010 |
Viscosity-dependent dynamics of CO rebinding to microperoxidase-8 in glycerol/water solution.
Topics: Animals; Carbon Monoxide; Catalytic Domain; Glycerol; Heme; Kinetics; Models, Molecular; Peroxidases; Protein Binding; Solutions; Temperature; Viscosity; Water | 2010 |
Probing the chemotaxis periplasmic sensor domains from Geobacter sulfurreducens by combined resonance Raman and molecular dynamic approaches: NO and CO sensing.
Topics: Carbon Monoxide; Chemotaxis; Geobacter; Heme; Ligands; Molecular Dynamics Simulation; Nitric Oxide; Oxidation-Reduction; Periplasmic Proteins; Protein Binding; Protein Structure, Tertiary; Spectrum Analysis, Raman | 2010 |
Immunoregulatory properties of heme oxygenase-1.
Topics: Animals; Anti-Inflammatory Agents; Autoimmunity; Biliverdine; Carbon Monoxide; Cell Culture Techniques; Cytokines; Heme; Heme Oxygenase-1; Humans; Hypersensitivity; Immune System Diseases; Mice; Oxidative Stress; Rats; Suppressor Factors, Immunologic | 2011 |
A specific interaction of L-tryptophan with CO of CO-bound indoleamine 2,3-dioxygenase identified by resonance Raman spectroscopy.
Topics: Carbon Monoxide; Heme; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Iron; Spectrum Analysis, Raman; Stereoisomerism; Tryptophan | 2010 |
Quantitating carbon monoxide production from heme by vascular plant preparations in vitro.
Topics: Carbon Monoxide; Chloroplasts; Chromatography, Gas; Heme; NADP; Oxygen; Plant Structures; Plants; Solanum tuberosum; Spinacia oleracea | 2011 |
Reciprocal regulation of Ca²+-activated outward K+ channels of Pyrus pyrifolia pollen by heme and carbon monoxide.
Topics: Carbon Monoxide; Germination; Heme; Ion Channel Gating; NADP; Pollen; Pollen Tube; Potassium Channels, Calcium-Activated; Protoplasts; Pyrus | 2011 |
Molecular basis for the inability of an oxygen atom donor ligand to replace the natural sulfur donor heme axial ligand in cytochrome P450 catalysis. Spectroscopic characterization of the Cys436Ser CYP2B4 mutant.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Circular Dichroism; Cysteine; Cytochrome P450 Family 2; Heme; Iron; Ligands; Models, Molecular; Nitrogen Oxides; Oxygen; Point Mutation; Spectrophotometry; Sulfur | 2011 |
Heme oxygenase system in hepatic ischemia-reperfusion injury.
Topics: Adaptive Immunity; Animals; Antioxidants; Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Humans; Immunomodulation; Iron; Liver; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neutrophils; Reperfusion Injury | 2010 |
Reduction of oxaporphyrin ring of CO-bound α-verdoheme complexed with heme oxygenase-1 by NADPH-cytochrome P450 reductase.
Topics: Anaerobiosis; Animals; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Ferrous Compounds; Heme; Heme Oxygenase-1; NADPH-Ferrihemoprotein Reductase; Oxidation-Reduction; Porphyrins; Rats | 2011 |
Crystal structure of the carbon monoxide complex of human cytoglobin.
Topics: Animals; Carbon Monoxide; Crystallization; Cytoglobin; Dithionite; Drosophila Proteins; Globins; Heme; Hemoglobins; Humans; Mice; Models, Molecular; Nerve Tissue Proteins; Neuroglobin; Protein Binding; Protein Conformation; X-Ray Diffraction | 2011 |
PAS/poly-HAMP signalling in Aer-2, a soluble haem-based sensor.
Topics: Adaptation, Physiological; Amino Acid Sequence; Bacterial Proteins; Carbon Monoxide; Chemotaxis; Escherichia coli; Escherichia coli Proteins; Heme; Molecular Sequence Data; Nitric Oxide; Oxygen; Protein Binding; Protein Structure, Quaternary; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Deletion; Signal Transduction; Solubility | 2011 |
Kinetics of carbon monoxide migration and binding in solvated neuroglobin as revealed by molecular dynamics simulations and quantum mechanical calculations.
Topics: Animals; Carbon Monoxide; Diffusion; Globins; Heme; Kinetics; Mice; Molecular Dynamics Simulation; Movement; Nerve Tissue Proteins; Neuroglobin; Protein Binding; Protein Conformation; Quantum Theory; Solvents | 2011 |
Crystal structures of CO and NO adducts of MauG in complex with pre-methylamine dehydrogenase: implications for the mechanism of dioxygen activation.
Topics: Amino Acid Sequence; Bacterial Proteins; Binding Sites; Biocatalysis; Carbon Monoxide; Crystallography, X-Ray; Cytochrome-c Peroxidase; Ferrous Compounds; Glutamic Acid; Heme; Hemeproteins; Indolequinones; Models, Chemical; Models, Molecular; Molecular Sequence Data; Molecular Structure; Nitric Oxide; Oxidoreductases; Oxidoreductases Acting on CH-NH Group Donors; Oxygen; Paracoccus denitrificans; Protein Binding; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Spectrophotometry; Substrate Specificity; Tryptophan | 2011 |
Electronic ground states and vibrational frequency shifts of diatomic ligands in heme adducts.
Topics: Carbon Monoxide; Electrons; Heme; Ligands; Nitric Oxide; Oxygen; Quantum Theory; Vibration | 2011 |
Fibrinogen is a heme-associated, carbon monoxide sensing molecule: a preliminary report.
Topics: Blood Coagulation; Carbon Monoxide; Fibrinogen; Heme; Humans; Kinetics; Organometallic Compounds; Plasma; Tandem Mass Spectrometry; Thrombelastography; Thrombosis | 2011 |
Molecular dynamics simulation of carboxy and deoxy human cytoglobin in solution.
Topics: Amino Acid Motifs; Binding Sites; Carbon Monoxide; Cytoglobin; Globins; Heme; Humans; Molecular Dynamics Simulation; Protein Binding; Protein Structure, Tertiary; Surface Properties | 2011 |
Electron transfer function versus oxygen delivery: a comparative study for several hexacoordinated globins across the animal kingdom.
Topics: Amino Acid Sequence; Animals; Caenorhabditis elegans; Caenorhabditis elegans Proteins; Carbon Monoxide; Cytochromes c; Cytoglobin; Electron Transport; Globins; Heme; Histidine; Humans; Iron; Kinetics; Nerve Tissue Proteins; Neuroglobin; Oxygen; Protein Structure, Quaternary; Protein Structure, Tertiary | 2011 |
A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase.
Topics: Binding Sites; Carbon Monoxide; Computer Simulation; Electron Spin Resonance Spectroscopy; Guanylate Cyclase; Heme; Hemeproteins; Humans; Kinetics; Models, Molecular; Nitric Oxide; Protein Binding; Protein Conformation; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Signal Transduction; Soluble Guanylyl Cyclase; Spectrophotometry, Ultraviolet | 2011 |
Redox-based thrombelastographic method to detect carboxyhemefibrinogen-mediated hypercoagulability.
Topics: Blood Coagulation; Calcium; Carbon Monoxide; Dose-Response Relationship, Drug; Elastic Modulus; Fibrinogen; Heme; Humans; Hydroxylamines; Organometallic Compounds; Oxidation-Reduction; Plasma; Protein Binding; Smoking; Thrombelastography; Thrombophilia; Thromboplastin | 2011 |
Two-dimensional IR spectroscopy of protein dynamics using two vibrational labels: a site-specific genetically encoded unnatural amino acid and an active site ligand.
Topics: Amino Acid Substitution; Amino Acids; Azides; Carbon Monoxide; Heme; Ligands; Molecular Dynamics Simulation; Mutation; Myoglobin; Protein Binding; Protein Conformation; Spectrophotometry, Infrared; Spectroscopy, Fourier Transform Infrared; Vibration | 2011 |
Evidence for the presence of two conformations of the heme a3-Cu(B) pocket of cytochrome caa3 from Thermus thermophilus.
Topics: Carbon Monoxide; Catalytic Domain; Copper; Crystallography, X-Ray; Cytochrome c Group; Cytochromes a; Cytochromes a3; Heme; Photolysis; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermus thermophilus | 2011 |
Reversible heme-dependent regulation of human cystathionine β-synthase by a flavoprotein oxidoreductase.
Topics: Allosteric Regulation; Carbon Monoxide; Cystathionine beta-Synthase; Ferric Compounds; Ferrous Compounds; Flavoproteins; Heme; Humans; Hydrogen Sulfide; Oxidation-Reduction; Oxidoreductases | 2011 |
Evidence for pH-dependent multiple conformers in iron(II) heme-human serum albumin: spectroscopic and kinetic investigation of carbon monoxide binding.
Topics: Binding Sites; Carbon Monoxide; Ferrous Compounds; Heme; Humans; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Serum Albumin; Spectrum Analysis, Raman | 2012 |
Carbon monoxide poisoning is prevented by the energy costs of conformational changes in gas-binding haemproteins.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Carbon Monoxide; Carbon Monoxide Poisoning; Crystallization; Crystallography, X-Ray; Cytochromes c'; Ferrous Compounds; Heme; Humans; Kinetics; Models, Chemical; Models, Molecular; Mutation; Oxidation-Reduction; Protein Binding; Protein Conformation; Spectrum Analysis, Raman | 2011 |
Aldoxime dehydratase: probing the heme environment involved in the synthesis of the carbon-nitrogen triple bond.
Topics: Carbon; Carbon Monoxide; Catalytic Domain; Heme; Hydro-Lyases; Ligands; Models, Molecular; Nitrogen; Propionates; Protons; Rhodococcus; Spectroscopy, Fourier Transform Infrared | 2011 |
Strong ligand-protein interactions revealed by ultrafast infrared spectroscopy of CO in the heme pocket of the oxygen sensor FixL.
Topics: Bacterial Proteins; Bradyrhizobium; Carbon Monoxide; Crystallography, X-Ray; Globins; Heme; Hemeproteins; Histidine Kinase; Ligands; Models, Molecular; Oxygen; Spectrophotometry, Infrared; Thermodynamics | 2011 |
Leu65 in the heme distal side is critical for the stability of the Fe(II)-O2 complex of YddV, a globin-coupled oxygen sensor diguanylate cyclase.
Topics: Carbon Monoxide; Escherichia coli Proteins; Ferric Compounds; Heme; Leucine; Oxygen; Phosphorus-Oxygen Lyases | 2012 |
Carbon monoxide and nitric oxide modulate α₂-antiplasmin and plasmin activity: role of heme.
Topics: alpha-2-Antiplasmin; Antifibrinolytic Agents; Carbon Monoxide; Chromatography, Liquid; Dose-Response Relationship, Drug; Fibrinolysin; Fibrinolysis; Heme; Humans; Hydrazines; Hydroxylamines; Nitric Oxide; Organometallic Compounds; Plasma; Protein Binding; Smoking; Tandem Mass Spectrometry; Thrombelastography; Thrombosis; Tissue Plasminogen Activator | 2011 |
Heme breakdown and ischemia/reperfusion injury in grafted liver during living donor liver transplantation.
Topics: Adolescent; Adult; Animals; Carbon Monoxide; Exhalation; Female; Heme; Heme Oxygenase-1; Humans; Liver Transplantation; Living Donors; Male; Middle Aged; Reperfusion Injury; Young Adult | 2012 |
Temperature dependence of the heat diffusivity of proteins.
Topics: Animals; Carbon Monoxide; Energy Transfer; Heme; Hot Temperature; Infrared Rays; Kinetics; Male; Molecular Dynamics Simulation; Mutation; Myoglobin; Protein Binding; Protein Conformation; Solvents; Spermatozoa; Thermodynamics; Vibration; Water; Whales | 2012 |
Structural characterization of a carbon monoxide adduct of a heme-DNA complex.
Topics: Carbon Monoxide; DNA; G-Quadruplexes; Heme; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Quantum Theory | 2012 |
Heme oxygenases from Arabidopsis thaliana reveal different mechanisms of carbon monoxide binding.
Topics: Arabidopsis; Arabidopsis Proteins; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Kinetics; Protein Binding; Spectroscopy, Fourier Transform Infrared | 2012 |
Quaternary structure controls ligand dynamics in soluble guanylate cyclase.
Topics: Allosteric Regulation; Animals; Carbon Monoxide; Cattle; Guanylate Cyclase; Heme; Humans; Ligands; Light; Lung; Nitric Oxide; Oxidation-Reduction; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Structure-Activity Relationship | 2012 |
Structural changes that occur upon photolysis of the Fe(II)(a3)-CO complex in the cytochrome ba(3)-oxidase of Thermus thermophilus: a combined X-ray crystallographic and infrared spectral study demonstrates CO binding to Cu(B).
Topics: Bacterial Proteins; Binding Sites; Carbon Monoxide; Catalytic Domain; Copper; Crystallography, X-Ray; Cytochrome b Group; Electron Transport Complex IV; Ferrous Compounds; Heme; Iron; Models, Molecular; Mutation; Photolysis; Protein Conformation; Spectroscopy, Fourier Transform Infrared; Thermus thermophilus; X-Rays | 2012 |
Heme reactivity is uncoupled from quaternary structure in gel-encapsulated hemoglobin: a resonance Raman spectroscopic study.
Topics: Carbon Monoxide; Heme; Hemoglobin A; Humans; Immobilized Proteins; Models, Molecular; Protein Structure, Tertiary; Spectrum Analysis, Raman | 2012 |
Direct and mediated electrochemical response of the cytochrome P450 106A2 from Bacillus megaterium ATCC 13368.
Topics: Bacillus megaterium; Bacterial Proteins; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Electrochemical Techniques; Electrodes; Electron Transport; Ferredoxins; Heme; Ligands; Oxidation-Reduction; Polysorbates; Water | 2012 |
Insights into the anomalous heme pocket of rainbow trout myoglobin.
Topics: Animals; Carbon Monoxide; Fluorides; Heme; Myoglobin; Oncorhynchus mykiss; Oxygen; Spectrophotometry, Ultraviolet; Spectrum Analysis, Raman | 2012 |
Impairment of heme synthesis in myelin as potential trigger of multiple sclerosis.
Topics: Biosynthetic Pathways; Carbon Monoxide; Environmental Pollutants; Heme; Humans; Metals, Heavy; Models, Biological; Multiple Sclerosis; Myelin Sheath | 2012 |
Structural characterization of spectroscopic substates in carbonmonoxy neuroglobin.
Topics: Animals; Carbon Monoxide; Chemistry, Physical; Globins; Heme; Histidine; Humans; Hydrogen Bonding; Mice; Molecular Dynamics Simulation; Myoglobin; Nerve Tissue Proteins; Neuroglobin; Protein Conformation; Protons; Quantum Theory; Spectrophotometry, Infrared; Stereoisomerism; Thermodynamics | 2011 |
Effect of DNA binding on geminate CO recombination kinetics in CO-sensing transcription factor CooA.
Topics: Allosteric Site; Bacteria; Bacterial Proteins; Carbon Monoxide; DNA; DNA-Binding Proteins; Heme; Hemeproteins; Kinetics; Ligands; Models, Molecular; Models, Statistical; Molecular Conformation; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; Rhodospirillum rubrum; Time Factors; Trans-Activators; Transcription, Genetic | 2012 |
Structural dynamics of proximal heme pocket in HemAT-Bs associated with oxygen dissociation.
Topics: Bacillus subtilis; Bacterial Proteins; Carbon Monoxide; Escherichia coli; Gene Expression; Heme; Heme-Binding Proteins; Hemeproteins; Histidine; Iron; Kinetics; Oxygen; Protein Structure, Tertiary; Recombinant Fusion Proteins; Signal Transduction; Spectrum Analysis, Raman | 2012 |
Timing of electron and proton transfer in the ba(3) cytochrome c oxidase from Thermus thermophilus.
Topics: Carbon Monoxide; Catalytic Domain; Copper; Cytochrome b Group; Electron Transport; Electron Transport Complex IV; Electrons; Heme; Kinetics; Models, Molecular; Oxidation-Reduction; Oxygen; Protons; Thermus thermophilus | 2012 |
Ligand binding, reactivity and biological activity of a distal pocket mutant of neuroglobin.
Topics: Apoptosis; Carbon Monoxide; Caspase 9; Cell Line; Cytochromes c; Enzyme Activation; Globins; Heme; Humans; Ligands; Mutant Proteins; Nerve Tissue Proteins; Neuroglobin; Oxidation-Reduction; Oxygen; Protein Binding; Protein Conformation | 2012 |
Photochemical properties of a myoglobin-CdTe quantum dot conjugate.
Topics: Cadmium Compounds; Carbon Monoxide; Electron Transport; Heme; Luminescence; Models, Molecular; Myoglobin; Oxidation-Reduction; Quantum Dots; Sulfhydryl Compounds; Tellurium | 2012 |
Mechanism-based inactivation of cytochrome P450 2B6 by methadone through destruction of prosthetic heme.
Topics: Analgesics, Opioid; Aryl Hydrocarbon Hydroxylases; Biotransformation; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2B6; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heme; Humans; Kinetics; Methadone; NADP; Oxidoreductases, N-Demethylating; Recombinant Proteins; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet | 2012 |
Carbon monoxide binding to the heme group at the dimeric interface modulates structure and copper accessibility in the Cu,Zn superoxide dismutase from Haemophilus ducreyi: in silico and in vitro evidences.
Topics: Carbon Monoxide; Catalytic Domain; Copper; Haemophilus ducreyi; Heme; Hydrogen Bonding; Models, Molecular; Protein Binding; Superoxide Dismutase | 2012 |
Carbon monoxide recombination dynamics in truncated hemoglobins studied with visible-pump midIR-probe spectroscopy.
Topics: Actinomycetales; Bacillus subtilis; Carbon Monoxide; Heme; Kinetics; Light; Photolysis; Spectrophotometry, Infrared; Truncated Hemoglobins | 2012 |
Influence of heme post-translational modification and distal ligation on the backbone dynamics of a monomeric hemoglobin.
Topics: Bacterial Proteins; Carbon Monoxide; Cyanides; Heme; Histidine; Molecular Dynamics Simulation; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Synechococcus; Truncated Hemoglobins | 2012 |
Identification of a haem domain in human soluble adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Binding Sites; Carbon Monoxide; Catalytic Domain; Cyclic AMP; Heme; Humans; Iron; Male; Mice; Muscle, Skeletal; Nitric Oxide; Protein Structure, Tertiary; Testis | 2012 |
Bovine carbonyl lactoperoxidase structure at 2.0Å resolution and infrared spectra as a function of pH.
Topics: Animals; Carbon Monoxide; Cattle; Crystallography, X-Ray; Heme; Hydrogen-Ion Concentration; Lactoperoxidase; Milk; Models, Molecular; Molecular Structure; Protein Conformation; Spectrophotometry, Infrared | 2012 |
On CO egress from, and re-uptake by, the enzyme MauG, as a mimic of the acquisition of oxidizing agents by the pre-MADH_MauG system. A molecular mechanics approach.
Topics: Binding Sites; Carbon Monoxide; Heme; Hemeproteins; Molecular Dynamics Simulation; Oxidants; Oxidoreductases Acting on CH-NH Group Donors; Paracoccus denitrificans; Protein Conformation | 2012 |
Specific function of the Met-Tyr-Trp adduct radical and residues Arg-418 and Asp-137 in the atypical catalase reaction of catalase-peroxidase KatG.
Topics: Amino Acid Motifs; Amino Acid Substitution; Bacterial Proteins; Carbon Monoxide; Catalase; Catalytic Domain; Free Radicals; Heme; Hydrogen-Ion Concentration; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; Mycobacterium tuberculosis; Oxygen; Protein Multimerization; Quantum Theory | 2012 |
Spectroscopic and kinetic investigation of the fully reduced and mixed valence states of ba3-cytochrome c oxidase from Thermus thermophilus: a Fourier transform infrared (FTIR) and time-resolved step-scan FTIR study.
Topics: Bacterial Proteins; Carbon Monoxide; Cytochrome b Group; Electron Transport Complex IV; Heme; Hydrogen-Ion Concentration; Kinetics; Oxidation-Reduction; Photolysis; Protein Binding; Quantum Theory; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Thermus thermophilus | 2012 |
High resolution crystal structures of the Cerebratulus lacteus mini-Hb in the unligated and carbomonoxy states.
Topics: Animals; Binding Sites; Carbon Monoxide; Crystallography, X-Ray; Heme; Hemoglobins; Hydrogen Bonding; Kinetics; Models, Molecular; Oxygen; Protein Structure, Secondary; Protein Structure, Tertiary; Thermodynamics | 2012 |
Heme modulates smooth muscle cell proliferation and migration via NADPH oxidase: a counter-regulatory role for heme oxygenase system.
Topics: Animals; Biliverdine; Carbon Monoxide; Cell Line; Cell Movement; Cell Proliferation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Heme; Heme Oxygenase (Decyclizing); Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; NADPH Oxidases; NF-kappa B; Rats; Reactive Oxygen Species; Signal Transduction; Time Factors | 2012 |
Heme binding properties of glyceraldehyde-3-phosphate dehydrogenase.
Topics: Animals; Carbon Monoxide; Circular Dichroism; Electron Spin Resonance Spectroscopy; Ferric Compounds; Ferrous Compounds; Glyceraldehyde-3-Phosphate Dehydrogenases; Heme; Humans; Ligands; Oxidation-Reduction; Porphyrins; Potentiometry; Protein Binding; Protein Structure, Secondary; Rabbits; Spectrum Analysis, Raman | 2012 |
Freezing does not decrease carbon monoxide-mediated hypercoagulation and hypofibrinolysis in human plasma.
Topics: Blood Coagulation; Carbon Monoxide; Dry Ice; Freezing; Heme; Humans; Kinetics; Organometallic Compounds; Specimen Handling; Thrombelastography; Thromboplastin; Tissue Plasminogen Activator | 2012 |
Comparative study of enzyme activity and heme reactivity in Drosophila melanogaster and Homo sapiens cystathionine β-synthases.
Topics: Amino Acid Sequence; Animals; Carbon Monoxide; Conserved Sequence; Cystathionine beta-Synthase; Drosophila melanogaster; Drosophila Proteins; Enzyme Stability; Evolution, Molecular; Heme; Humans; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; Nitric Oxide; Oxidation-Reduction; Protein Binding | 2013 |
Detection of heme oxygenase activity by measurement of CO.
Topics: Animals; Biological Assay; Carbon Monoxide; Chromatography, Gas; Equipment Design; Heme; Heme Oxygenase (Decyclizing); Humans; Limit of Detection; Reproducibility of Results | 2001 |
Factors that distort the heme structure in Heme-Nitric Oxide/OXygen-Binding (H-NOX) protein domains. A theoretical study.
Topics: Algorithms; Bacterial Proteins; Binding Sites; Carbon Monoxide; Carrier Proteins; Computer Simulation; Heme; Iron-Binding Proteins; Models, Molecular; Molecular Conformation; Nitric Oxide; Oxygen; Protein Binding; Protein Structure, Tertiary; Quantum Theory | 2013 |
Accommodation of CO in the di-heme active site of cytochrome bd terminal oxidase from Escherichia coli.
Topics: Carbon Monoxide; Catalytic Domain; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Kinetics; Oxidoreductases; Photolysis; Protein Binding | 2013 |
Detailed transient heme structures of Mb-CO in solution after CO dissociation: an X-ray transient absorption spectroscopic study.
Topics: Carbon Monoxide; Electrons; Ferrous Compounds; Heme; Myoglobin; Photolysis; Protein Structure, Tertiary; Solutions; Temperature; Thermodynamics; X-Ray Absorption Spectroscopy | 2013 |
Conformational dynamics in human neuroglobin: effect of His64, Val68, and Cys120 on ligand migration.
Topics: Amino Acid Sequence; Calorimetry; Carbon Monoxide; Cysteine; Globins; Heme; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Nerve Tissue Proteins; Neuroglobin; Protein Conformation; Thermodynamics | 2012 |
Thrombelastographic characterization of coagulation/fibrinolysis in horses: role of carboxyheme and metheme states.
Topics: Animals; Blood Coagulation; Blood Coagulation Tests; Carbon Monoxide; Carboxyhemoglobin; Enteritis; Heme; Horses; Hydroxylamines; Male; Methemoglobin; Nitric Oxide; Organometallic Compounds; Severity of Illness Index; Thrombelastography; Thrombosis; Tissue Plasminogen Activator | 2013 |
Dynamic factors affecting gaseous ligand binding in an artificial oxygen transport protein.
Topics: Binding Sites; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Globins; Glutamic Acid; Heme; Histidine; Kinetics; Ligands; Mutant Proteins; Nuclear Magnetic Resonance, Biomolecular; Oxidation-Reduction; Oxygen; Protein Binding; Protein Conformation; Protein Engineering; Protein Folding; Recombinant Proteins; Water | 2013 |
A new way to degrade heme: the Mycobacterium tuberculosis enzyme MhuD catalyzes heme degradation without generating CO.
Topics: Bacterial Proteins; Carbon Monoxide; Catalytic Domain; Gene Expression Regulation, Bacterial; Heme; Heme Oxygenase (Decyclizing); Magnetic Resonance Spectroscopy; Models, Chemical; Mycobacterium tuberculosis; NADPH-Ferrihemoprotein Reductase; Oxygenases; Spectrometry, Mass, Electrospray Ionization; Spectrum Analysis, Raman | 2013 |
Ligand-rebinding kinetics of 2/2 hemoglobin from the Antarctic bacterium Pseudoalteromonas haloplanktis TAC125.
Topics: Antarctic Regions; Carbon Monoxide; Heme; Hemoglobins; Hydrogen Bonding; Iron; Kinetics; Models, Molecular; Oxidation-Reduction; Oxygen; Photolysis; Pressure; Protein Binding; Pseudoalteromonas | 2013 |
Relationship between the electron density of the heme Fe atom and the vibrational frequencies of the Fe-bound carbon monoxide in myoglobin.
Topics: Animals; Carbon Monoxide; Electrons; Heme; Iron; Kinetics; Myoglobin; Vibration | 2013 |
An engineered heme-copper center in myoglobin: CO migration and binding.
Topics: Animals; Binding Sites; Carbon Monoxide; Catalytic Domain; Copper; Heme; Kinetics; Male; Models, Molecular; Mutation; Myoglobin; Photolysis; Protein Binding; Spectroscopy, Fourier Transform Infrared; Temperature; Whales | 2013 |
Primary processes in heme-based sensor proteins.
Topics: Bacterial Proteins; Carbon Monoxide; Guanylate Cyclase; Heme; Hemeproteins; Kinetics; Models, Molecular; Nitric Oxide; Oxygen; Protein Binding; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Soluble Guanylyl Cyclase | 2013 |
Functional and structural roles of the N-terminal extension in Methanosarcina acetivorans protoglobin.
Topics: Amino Acid Sequence; Azides; Carbon Monoxide; Globins; Heme; Kinetics; Methanosarcina; Molecular Sequence Data; Mutation; Nitric Oxide; Protein Binding; Protein Carbonylation; Protein Structure, Secondary; Sequence Homology, Amino Acid | 2013 |
A model theoretical study on ligand exchange reactions of CooA.
Topics: Bacterial Proteins; Carbon Monoxide; Cysteine; Ferric Compounds; Ferrous Compounds; Gases; Heme; Hemeproteins; Ligands; Models, Molecular; Quantum Theory; Rhodospirillum rubrum; Trans-Activators | 2013 |
Importance of many-body effects in the Kernel of hemoglobin for ligand binding.
Topics: Carbon Monoxide; Heme; Hemoglobins; Humans; Ligands; Models, Chemical; Models, Molecular; Oxygen; Spectrophotometry, Infrared; Structure-Activity Relationship; Thermodynamics | 2013 |
Reciprocal allosteric modulation of carbon monoxide and warfarin binding to ferrous human serum heme-albumin.
Topics: Allosteric Regulation; Carbon Monoxide; Ferrous Compounds; Heme; Humans; Kinetics; Protein Binding; Serum Albumin; Thermodynamics; Warfarin | 2013 |
Quercetin suppressed CYP2E1-dependent ethanol hepatotoxicity via depleting heme pool and releasing CO.
Topics: Animals; Antioxidants; Carbon Monoxide; Cells, Cultured; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Ethanol; Gene Expression Regulation; Heme; Heme Oxygenase-1; Hepatocytes; Humans; Lipid Peroxidation; Liver; Male; Oxidative Stress; Protective Agents; Quercetin; Rats; Rats, Sprague-Dawley | 2013 |
Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide.
Topics: Bacterial Proteins; Carbon Monoxide; Formaldehyde; Heme; Hydrolysis; Mixed Function Oxygenases; Oxygenases; Staphylococcus aureus | 2013 |
Heme bound amylin: spectroscopic characterization, reactivity, and relevance to type 2 diabetes.
Topics: Amino Acid Sequence; Carbon Monoxide; Catalase; Diabetes Mellitus, Type 2; Heme; Humans; Islet Amyloid Polypeptide; Models, Molecular; Molecular Sequence Data; Oxidative Stress; Peroxidase; Reactive Oxygen Species; Spectrum Analysis | 2013 |
Cytochrome bd-I in Escherichia coli is less sensitive than cytochromes bd-II or bo'' to inhibition by the carbon monoxide-releasing molecule, CORM-3: N-acetylcysteine reduces CO-RM uptake and inhibition of respiration.
Topics: Acetylcysteine; Antioxidants; Carbon Monoxide; Cell Membrane; Cell Respiration; Cytochrome b Group; Cytochromes; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Hyperbaric Oxygenation; Leghemoglobin; Organometallic Compounds; Oxidoreductases; Oxygen Consumption; Ruthenium | 2013 |
Effects of local protein environment on the binding of diatomic molecules to heme in myoglobins. DFT and dispersion-corrected DFT studies.
Topics: Amino Acid Motifs; Binding Sites; Carbon Monoxide; Heme; Histidine; Humans; Hydrogen Bonding; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myoglobin; Oxygen; Protein Binding; Quantum Theory; Thermodynamics | 2013 |
Kinetics of reversible reductive carbonylation of heme in human cystathionine β-synthase.
Topics: Carbon Monoxide; Cystathionine beta-Synthase; Cysteine; Heme; Histidine; Humans; Kinetics; Ligands; Oxygen; Protein Binding; Protein Carbonylation; Signal Transduction; Spectrum Analysis, Raman; Sulfur Dioxide; Superoxides | 2013 |
Heme oxygenase-1 regulates matrix metalloproteinase MMP-1 secretion and chondrocyte cell death via Nox4 NADPH oxidase activity in chondrocytes.
Topics: Apoptosis; Carbon Monoxide; Chondrocytes; DNA Fragmentation; Green Fluorescent Proteins; HEK293 Cells; Heme; Heme Oxygenase-1; Humans; Interleukin-1beta; Matrix Metalloproteinase 1; NADPH Oxidase 4; NADPH Oxidases; Osteoarthritis; Protein Multimerization; Protein Transport; Recombinant Fusion Proteins | 2013 |
Investigations of heme ligation and ligand switching in cytochromes p450 and p420.
Topics: Camphor 5-Monooxygenase; Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Histidine; Ligands; Models, Molecular; Myoglobin; Protein Conformation; Spectrum Analysis, Raman | 2013 |
Isoniazid inhibits the heme-based reactivity of Mycobacterium tuberculosis truncated hemoglobin N.
Topics: Antitubercular Agents; Azides; Bacterial Proteins; Biocatalysis; Carbon Monoxide; Heme; Isomerism; Isoniazid; Molecular Docking Simulation; Mycobacterium tuberculosis; Oxygen; Peroxynitrous Acid; Protein Binding; Protein Conformation; Truncated Hemoglobins | 2013 |
IR signatures of the metal centres of bovine cytochrome c oxidase: assignments and redox-linkage.
Topics: Animals; Carbon Monoxide; Cattle; Copper; Cyanides; Electron Transport Complex IV; Heme; Infrared Rays; Ligands; Oxidation-Reduction; Spectroscopy, Fourier Transform Infrared | 2013 |
Dynamics of α-Hb chain binding to its chaperone AHSP depends on heme coordination and redox state.
Topics: Blood Proteins; Carbon Monoxide; Circular Dichroism; Heme; Hemoglobin A; Humans; Kinetics; Molecular Chaperones; Mutagenesis, Site-Directed; Oxidation-Reduction; Oxygen; Protein Binding; Recombinant Proteins | 2014 |
Intersubunit communication via changes in hemoglobin quaternary structures revealed by time-resolved resonance Raman spectroscopy: direct observation of the Perutz mechanism.
Topics: Carbon Monoxide; Heme; Hemoglobins; Histidine; Humans; Iron; Models, Molecular; Nickel; Protein Structure, Quaternary; Protein Subunits; Spectrum Analysis, Raman; Time Factors | 2013 |
Electronic and nuclear structural snapshots in ligand dissociation and recombination processes of iron porphyrin in solution: a combined optical/X-ray approach.
Topics: Carbon Monoxide; Electrons; Imidazoles; Kinetics; Ligands; Myoglobin; Photolysis; Protoporphyrins; Solutions; Spectrophotometry, Ultraviolet; Water; X-Ray Absorption Spectroscopy | 2013 |
Identification of proximal and distal axial ligands in Leishmania major pseudoperoxidase.
Topics: Amino Acid Substitution; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Heme; Hydrogen-Ion Concentration; Imidazoles; Leishmania major; Ligands; Models, Molecular; Mutagenesis, Site-Directed; Peroxidase; Protein Binding; Protozoan Proteins; Structural Homology, Protein | 2013 |
YC-1 binding to the β subunit of soluble guanylyl cyclase overcomes allosteric inhibition by the α subunit.
Topics: Allosteric Regulation; Animals; Carbon Monoxide; Cattle; Guanylate Cyclase; Heme; Indazoles; Manduca; Models, Molecular; Nitric Oxide; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein Subunits; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Surface Plasmon Resonance | 2014 |
Electronic control of discrimination between O2 and CO in myoglobin lacking the distal histidine residue.
Topics: Animals; Carbon Monoxide; Electrons; Heme; Histidine; Mutant Proteins; Mutation; Myoglobin; Oxygen; Substrate Specificity; Vibration | 2014 |
Subclinical carbon monoxide limits apoptosis in the developing brain after isoflurane exposure.
Topics: Anesthetics, Inhalation; Animals; Animals, Newborn; Apoptosis; Brain; Carbon Monoxide; Carboxyhemoglobin; Caspase 3; Cytochrome-c Peroxidase; Cytochromes c; Female; Heme; Immunohistochemistry; In Situ Nick-End Labeling; Isoflurane; Mice; Mitochondria; Pregnancy | 2014 |
NO* binds human cystathionine β-synthase quickly and tightly.
Topics: Carbon Monoxide; Cystathionine beta-Synthase; Heme; Humans; Kinetics; Nitric Oxide; Oxidation-Reduction; Protein Binding | 2014 |
Structural analysis and identification of PhuS as a heme-degrading enzyme from Pseudomonas aeruginosa.
Topics: Bacterial Proteins; Biotransformation; Carbon Monoxide; Chromatography, Gas; Crystallography, X-Ray; Escherichia coli O157; Heme; Models, Molecular; Protein Binding; Protein Conformation; Pseudomonas aeruginosa; Spectrum Analysis | 2014 |
Disulfide bonds regulate binding of exogenous ligand to human cytoglobin.
Topics: Amino Acid Substitution; Carbon Monoxide; Cystine; Cytoglobin; Globins; Heme; Humans; Kinetics; Ligands; Mutagenesis, Site-Directed; Oxidation-Reduction; Potassium Cyanide; Protein Binding; Protein Multimerization; Spectrum Analysis, Raman | 2014 |
CO-dynamics in the active site of cytochrome c oxidase.
Topics: Carbon Monoxide; Catalytic Domain; Copper; Electron Transport Complex IV; Heme; Iron; Ligands; Myoglobin; Photolysis | 2014 |
Elevated carboxyhemoglobin in a marine mammal, the northern elephant seal.
Topics: Animals; Carbon Monoxide; Carboxyhemoglobin; Diving; Female; Heme; Oxygen; Seals, Earless | 2014 |
Heme utilization by pathogenic bacteria: not all pathways lead to biliverdin.
Topics: Bacteria; Biliverdine; Carbon Monoxide; Corynebacterium diphtheriae; Enzymes; Heme; Heme Oxygenase (Decyclizing); Hydroxylation; Iron; Neisseriaceae; Oxidation-Reduction; Protein Structure, Tertiary; Pseudomonas aeruginosa; Yin-Yang | 2014 |
Carbon monoxide-bound red blood cell resuscitation ameliorates hepatic injury induced by massive hemorrhage and red blood cell resuscitation via hepatic cytochrome P450 protection in hemorrhagic shock rats.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dapsone; Disease Models, Animal; Erythrocyte Transfusion; Erythrocytes; Heme; Liver; Liver Function Tests; Male; Oxidative Stress; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Resuscitation; Shock, Hemorrhagic | 2014 |
Engineering the internal cavity of neuroglobin demonstrates the role of the haem-sliding mechanism.
Topics: Carbon Monoxide; Crystallography, X-Ray; Globins; Heme; Kinetics; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroglobin; Protein Engineering | 2014 |
Distal-proximal crosstalk in the heme binding pocket of the NO sensor DNR.
Topics: Amino Acid Substitution; Bacterial Proteins; Binding Sites; Carbon Monoxide; Heme; Nitric Oxide; Protein Binding; Pseudomonas aeruginosa; Transcription Factors; X-Ray Absorption Spectroscopy | 2014 |
Dynamics of the heme-binding bacterial gas-sensing dissimilative nitrate respiration regulator (DNR) and activation barriers for ligand binding and escape.
Topics: Animals; Bacterial Proteins; Binding Sites; Carbon Monoxide; Cytochromes c; DNA, Bacterial; Fluorescence Polarization; Gene Expression Regulation, Bacterial; Heme; Horses; Kinetics; Ligands; Nitric Oxide; Promoter Regions, Genetic; Protein Binding; Pseudomonas aeruginosa; Transcription Factors | 2014 |
Introduction of water into the heme distal side by Leu65 mutations of an oxygen sensor, YddV, generates verdoheme and carbon monoxide, exerting the heme oxygenase reaction.
Topics: Carbon Monoxide; Escherichia coli Proteins; Heme; Heme Oxygenase (Decyclizing); Leucine; Mutation; Oxygen; Phosphorus-Oxygen Lyases; Water | 2014 |
Interaction of the carbon monoxide-releasing molecule Ru(CO)3Cl(glycinate) (CORM-3) with Salmonella enterica serovar Typhimurium: in situ measurements of carbon monoxide binding by integrating cavity dual-beam spectrophotometry.
Topics: Anti-Bacterial Agents; Carbon Monoxide; Electron Transport Chain Complex Proteins; Heme; Humans; Organometallic Compounds; Protein Binding; Salmonella typhimurium; Spectrophotometry | 2014 |
Can gas replace protein function? CO abrogates the oxidative toxicity of myoglobin.
Topics: Animals; Carbon Monoxide; Cattle; Haptoglobins; Heme; Hemoglobins; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Myoglobin; Myosins; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rabbits | 2014 |
Cytoglobin ligand binding regulated by changing haem-co-ordination in response to intramolecular disulfide bond formation and lipid interaction.
Topics: Ascorbic Acid; Azides; Carbon Monoxide; Cytoglobin; Disulfides; Electrophoresis, Polyacrylamide Gel; Globins; Heme; Humans; Iron; Ligands; Lipids; Mutant Proteins; Oleic Acid; Oxidation-Reduction; Protein Multimerization; Protein Stability; Recombinant Proteins | 2015 |
Role of α-globin H helix in the building of tetrameric human hemoglobin: interaction with α-hemoglobin stabilizing protein (AHSP) and heme molecule.
Topics: alpha-Globins; Amino Acid Sequence; Blood Proteins; Carbon Monoxide; Circular Dichroism; Glutathione Transferase; Heme; Hemoglobins; Humans; Kinetics; Molecular Chaperones; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Protein Structure, Quaternary; Protein Structure, Secondary; Recombinant Fusion Proteins; Spectrophotometry, Ultraviolet | 2014 |
Enteral supplements of a carbon monoxide donor CORM-A1 protect against cerebrovascular dysfunction caused by neonatal seizures.
Topics: Adenosine Diphosphate; Animals; Arterioles; Boranes; Bradykinin; Carbon Monoxide; Carbonates; Cerebrovascular Circulation; Cerebrovascular Disorders; Dietary Supplements; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Heme; Male; Quisqualic Acid; Seizures; Swine; Time Factors; Vasodilator Agents | 2015 |
Acute stress-induced antinociception is cGMP-dependent but heme oxygenase-independent.
Topics: Acute Pain; Animals; Carbon Monoxide; Cyclic GMP; Deuteroporphyrins; Heme; Heme Oxygenase (Decyclizing); Lysine; Male; Nociceptive Pain; Oxadiazoles; Pain Measurement; Rats, Wistar; Signal Transduction; Stress Disorders, Traumatic, Acute | 2014 |
CO-Releasing Molecules Have Nonheme Targets in Bacteria: Transcriptomic, Mathematical Modeling and Biochemical Analyses of CORM-3 [Ru(CO)3Cl(glycinate)] Actions on a Heme-Deficient Mutant of Escherichia coli.
Topics: Carbon Monoxide; Cell Membrane; Escherichia coli K12; Escherichia coli Proteins; Heme; Lactococcus lactis; Models, Theoretical; Mutation; Organometallic Compounds; Transcriptome | 2015 |
Stability of the antimalarial drug dihydroartemisinin under physiologically relevant conditions: implications for clinical treatment and pharmacokinetic and in vitro assays.
Topics: Animals; Antimalarials; Artemisinins; Ascorbic Acid; Carbon Monoxide; Chromatography, High Pressure Liquid; Drug Stability; Electrochemical Techniques; Erythrocytes; Half-Life; Heme; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Plasmodium falciparum; Temperature | 2015 |
Kinetic properties and heme pocket structure of two domains of the polymeric hemoglobin of Artemia in comparison with the native molecule.
Topics: Amino Acid Sequence; Animals; Artemia; Arthropod Proteins; Carbon Monoxide; Escherichia coli; Gene Expression; Heme; Hemoglobins; Kinetics; Models, Molecular; Molecular Sequence Data; Oxidation-Reduction; Oxygen; Polymerization; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Sequence Alignment; Thermodynamics | 2015 |
Kinetic Analysis of a Globin-Coupled Histidine Kinase, AfGcHK: Effects of the Heme Iron Complex, Response Regulator, and Metal Cations on Autophosphorylation Activity.
Topics: Adenosine Triphosphate; Bacterial Proteins; Carbon Monoxide; Cations, Divalent; Enzyme Activation; Globins; Heme; Histidine Kinase; Hydrogen-Ion Concentration; Iron; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Myxococcales; Oxidation-Reduction; Oxygen; Phosphorylation; Protein Kinases; Protein Structure, Tertiary; Recombinant Proteins; Signal Transduction | 2015 |
Direct observation of ultrafast collective motions in CO myoglobin upon ligand dissociation.
Topics: Animals; Carbon Monoxide; Crystallography, X-Ray; Heme; Horses; Iron; Ligands; Molecular Dynamics Simulation; Motion; Myoglobin; Photolysis; Protein Structure, Secondary | 2015 |
Measuring End-Tidal Carbon Monoxide of Jaundiced Neonates in the Birth Hospital to Identify Those with Hemolysis.
Topics: Bilirubin; Birthing Centers; Breath Tests; Carbon Monoxide; Female; Hematologic Tests; Heme; Hemolysis; Humans; Hyperbilirubinemia; Infant, Newborn; Jaundice, Neonatal; Male; Prospective Studies; United States | 2016 |
Solving Kinetic Equations for the Laser Flash Photolysis Experiment on Nitric Oxide Synthases: Effect of Conformational Dynamics on the Interdomain Electron Transfer.
Topics: Animals; Carbon Monoxide; Electrons; Heme; Humans; Kinetics; Lasers; Mice; Mutation; Nitric Oxide; Nitric Oxide Synthase; Photolysis; Protein Conformation; Rats | 2015 |
H-NOX from Clostridium botulinum, like H-NOX from Thermoanaerobacter tengcongensis, Binds Oxygen but with a Less Stable Oxyferrous Heme Intermediate.
Topics: Bacterial Proteins; Botulism; Carbon Monoxide; Clostridium botulinum; Heme; Hemeproteins; Humans; Kinetics; Nitric Oxide; Oxygen; Protein Binding; Thermoanaerobacter | 2015 |
S-Adenosyl-l-methionine Modulates CO and NO• Binding to the Human H2S-generating Enzyme Cystathionine β-Synthase.
Topics: Carbon Monoxide; Cystathionine beta-Synthase; Heme; Humans; Kinetics; Methionine; Nitric Oxide; Oxidation-Reduction; S-Adenosylmethionine | 2016 |
Characterization of Heme-DNA Complexes Composed of Some Chemically Modified Hemes and Parallel G-Quadruplex DNAs.
Topics: Carbon Monoxide; DNA; G-Quadruplexes; Heme; Iron; Magnetic Resonance Spectroscopy | 2015 |
Cytochromes c': Structure, Reactivity and Relevance to Haem-Based Gas Sensing.
Topics: Bacteria; Carbon Monoxide; Cytochromes c'; Heme; Models, Molecular; Nitric Oxide; Oxygen; Protein Binding; Protein Conformation; Spectrum Analysis | 2015 |
Kinetics of Nitrite Reduction and Peroxynitrite Formation by Ferrous Heme in Human Cystathionine β-Synthase.
Topics: Carbon Monoxide; Cystathionine beta-Synthase; Heme; Humans; Kinetics; Nitric Oxide; Nitrites; Oxidation-Reduction; Oxygen; Peroxynitrous Acid; Superoxides | 2016 |
Haem-dependent dimerization of PGRMC1/Sigma-2 receptor facilitates cancer proliferation and chemoresistance.
Topics: Carbon Monoxide; Cell Proliferation; Crystallography, X-Ray; Cytochrome P-450 Enzyme System; Drug Resistance, Neoplasm; ErbB Receptors; Heme; Humans; Membrane Proteins; Models, Biological; Neoplasms; Protein Binding; Protein Multimerization; Receptors, Progesterone; Receptors, sigma; Signal Transduction; Solutions | 2016 |
Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation.
Topics: Carbon Monoxide; Catalysis; Catalytic Domain; Dioxygenases; Heme; Heme Oxygenase (Decyclizing); Iron; Mixed Function Oxygenases; Mycobacterium tuberculosis; Oxidation-Reduction; Oxygen; Tuberculosis | 2016 |
Enhancements of the production of bilirubin and the expression of β-globin by carbon monoxide during erythroid differentiation.
Topics: Animals; beta-Globins; Bilirubin; Bone Marrow Cells; Carbon Monoxide; Cell Differentiation; Cells, Cultured; Erythroid Cells; Erythropoiesis; Gene Expression Regulation; Heme; Mice | 2016 |
Met(104) is the CO-replaceable ligand at Fe(II) heme in the CO-sensing transcription factor BxRcoM-1.
Topics: Burkholderia; Carbon Monoxide; Ferrous Compounds; Heme; Ligands; Methionine; Transcription Factors | 2016 |
The Heme-Based Oxygen Sensor Rhizobium etli FixL: Influence of Auxiliary Ligands on Heme Redox Potential and Implications on the Enzyme Activity.
Topics: Bacterial Proteins; Biosensing Techniques; Carbon Monoxide; Heme; Hemeproteins; Histidine Kinase; Oxygen; Rhizobium etli | 2016 |
The Dynamics Behind the Affinity: Controlling Heme-Gas Affinity via Geminate Recombination and Heme Propionate Conformation in the NO Carrier Cytochrome c'.
Topics: Alcaligenes; Carbon Monoxide; Cytochromes c; Heme; Kinetics; Molecular Conformation; Molecular Dynamics Simulation; Nitric Oxide; Propionates; Recombination, Genetic | 2016 |
Photoacoustic calorimetry studies of CO photo-dissociation from chloramine-T modified horse heart cytochrome-c.
Topics: Acoustics; Animals; Binding Sites; Calorimetry; Carbon Monoxide; Chloramines; Cytochromes c; Heme; Horses; Iron; Kinetics; Ligands; Light; Myocardium; Photolysis; Protein Conformation; Spectrophotometry, Ultraviolet; Sulfoxides; Thermodynamics; Tosyl Compounds | 2016 |
Crystal structures of the CO and NOBound DosS GAF-A domain and implications for DosS signaling in Mycobacterium tuberculosis.
Topics: Amino Acids; Bacterial Proteins; Carbon Monoxide; Catalysis; Crystallography, X-Ray; Heme; Hydrogen Bonding; Iron; Mycobacterium tuberculosis; Nitric Oxide; Oxidation-Reduction; Oxygen; Phosphorylation; Protamine Kinase; Protein Domains; Protein Multimerization; Protein Structure, Secondary; Signal Transduction | 2016 |
CO and NO bind to Fe(II) DiGeorge critical region 8 heme but do not restore primary microRNA processing activity.
Topics: Binding Sites; Carbon Monoxide; Circular Dichroism; Cysteine; Ferric Compounds; Ferrous Compounds; Heme; Histidine; Humans; Hydrogen-Ion Concentration; Ligands; Lysine; MicroRNAs; Models, Biological; Nitric Oxide; Protein Binding; RNA-Binding Proteins; Spectrum Analysis, Raman | 2016 |
Fine Sampling of the R→T Quaternary-Structure Transition of a Tetrameric Hemoglobin.
Topics: Animals; Carbon Monoxide; Crystallography, X-Ray; Heme; Hemoglobins; Hydrogen-Ion Concentration; Perciformes; Protein Structure, Quaternary; Protein Structure, Tertiary; Spectroscopy, Fourier Transform Infrared | 2017 |
Characterization of the interaction between heme and a parallel G-quadruplex DNA formed from d(TTGAGG).
Topics: Binding Sites; Carbon Monoxide; G-Quadruplexes; Heme; Models, Molecular; Nucleic Acid Denaturation; Oligonucleotides; Protein Binding; Protein Interaction Domains and Motifs; Proton Magnetic Resonance Spectroscopy; Structure-Activity Relationship; Temperature | 2017 |
Reciprocal regulation of carbon monoxide metabolism and the circadian clock.
Topics: Animals; ARNTL Transcription Factors; Carbon Monoxide; Cell Line, Tumor; Circadian Clocks; CLOCK Proteins; Drosophila melanogaster; Glucose; Heme; Heme Oxygenase (Decyclizing); Homeostasis; Humans; Male; Metabolic Networks and Pathways; Mice, Inbred C57BL; Mice, Knockout; Motor Activity; Protein Binding; Transcription, Genetic; Transcriptional Activation | 2017 |
Role of the Conserved Valine 236 in Access of Ligands to the Active Site of Thermus thermophilus ba
Topics: Bacterial Proteins; Binding Sites; Carbon Monoxide; Catalytic Domain; Crystallization; Crystallography, X-Ray; Cytochrome b Group; Electron Transport Complex IV; Heme; Kinetics; Ligands; Molecular Dynamics Simulation; Mutation, Missense; Nitric Oxide; Oxidation-Reduction; Oxygen; Protein Binding; Protein Domains; Spectrophotometry; Thermus thermophilus; Valine | 2017 |
Role of Ionic Strength and pH in Modulating Thermodynamic Profiles Associated with CO Escape from Rice Nonsymbiotic Hemoglobin 1.
Topics: Calorimetry; Carbon Monoxide; Heme; Hemeproteins; Histidine; Hydrogen-Ion Concentration; Iron; Kinetics; Ligands; Molecular Dynamics Simulation; Oryza; Osmolar Concentration; Plant Proteins; Protein Binding; Protein Conformation; Temperature; Thermodynamics | 2017 |
Biological signaling by carbon monoxide and carbon monoxide-releasing molecules.
Topics: Animals; Blood Flow Velocity; Blood Vessels; Carbon Monoxide; Heme; Humans; Models, Biological; Signal Transduction | 2017 |
Potential role of heme metabolism in the inducible expression of heme oxygenase-1.
Topics: Arsenites; Basic-Leucine Zipper Transcription Factors; Carbon Monoxide; Enzyme Induction; Fanconi Anemia Complementation Group Proteins; HEK293 Cells; HeLa Cells; Heme; Heme Oxygenase-1; Heptanoates; Humans; Isothiocyanates; Protoporphyrins; Sodium Compounds; Sulfoxides | 2017 |
A Clinically Relevant Variant of the Human Hydrogen Sulfide-Synthesizing Enzyme Cystathionine
Topics: Carbon Monoxide; Crystallography, X-Ray; Cystathionine beta-Synthase; Heme; Humans; Hydrogen Sulfide; Kinetics; Nitric Oxide; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Recombinant Proteins; S-Adenosylmethionine | 2017 |
Hydroxylamine-induced oxidation of ferrous carbonylated truncated hemoglobins from Mycobacterium tuberculosis and Campylobacter jejuni is limited by carbon monoxide dissociation.
Topics: Campylobacter jejuni; Carbon Monoxide; Heme; Hydroxylamine; Iron; Kinetics; Mycobacterium tuberculosis; Oxidation-Reduction; Truncated Hemoglobins | 2017 |
A nanosecond time-resolved XFEL analysis of structural changes associated with CO release from cytochrome c oxidase.
Topics: Carbon Monoxide; Electron Transport Complex IV; Heme; Hydrogen Bonding; Models, Molecular; Molecular Conformation; Molecular Structure; Oxidation-Reduction; Photolysis; Structure-Activity Relationship | 2017 |
Ultrafast CO Kinetics in Heme Proteins: Adiabatic Ligand Binding and Heavy Atom Tunneling.
Topics: Carbon Monoxide; Heme; Hemoglobins; Kinetics; Ligands; Myoglobin; Protein Binding; Quantum Theory; Thermodynamics | 2017 |
Carbon monoxide inhibits hemotoxic activity of Elapidae venoms: potential role of heme.
Topics: Animals; Antivenins; Blood Coagulation; Carbon Monoxide; Elapid Venoms; Elapidae; Heme; Humans; Hydroxylamines; Kinetics; Organometallic Compounds; Solutions; Thrombelastography | 2018 |
Spectral-Kinetic Analysis of Recombination Reaction of Heme Centers of bd-Type Quinol Oxidase from Escherichia coli with Carbon Monoxide.
Topics: Carbon Monoxide; Escherichia coli; Escherichia coli Proteins; Heme; Kinetics; Models, Chemical; Oxidoreductases; Spectrum Analysis | 2017 |
First Principles Calculation of the Reaction Rates for Ligand Binding to Myoglobin: The Cases of NO and CO.
Topics: Binding Sites; Carbon Monoxide; Diffusion; Heme; Iron; Kinetics; Ligands; Molecular Dynamics Simulation; Myoglobin; Nitric Oxide; Protein Binding; Protein Conformation; Quantum Theory; Thermodynamics | 2018 |
Mechanistic Insights into the Activation of Soluble Guanylate Cyclase by Carbon Monoxide: A Multistep Mechanism Proposed for the BAY 41-2272 Induced Formation of 5-Coordinate CO-Heme.
Topics: Animals; Carbon Monoxide; Cattle; Heme; Kinetics; Pyrazoles; Pyridines; Soluble Guanylyl Cyclase; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman | 2018 |
A mechanism for CO regulation of ion channels.
Topics: Amino Acid Motifs; Amino Acid Sequence; Carbon Monoxide; HEK293 Cells; Heme; Humans; Ion Channel Gating; Ion Channels; KATP Channels; Models, Molecular; Spectrum Analysis, Raman; Sulfonylurea Receptors | 2018 |
Comprehensive Biochemical and Biophysical Characterization of Hemoglobin-Based Oxygen Carrier Therapeutics: All HBOCs Are Not Created Equally.
Topics: Animals; Blood Substitutes; Carbon Monoxide; Cattle; Cell Line; Heme; Hemoglobins; Humans; Kinetics; Mice; Oxidation-Reduction; Oxygen; Protein Engineering | 2018 |
Testing the N-Terminal Velcro Model of CooA Carbon Monoxide Activation.
Topics: Bacterial Proteins; Carbon Monoxide; DNA; DNA-Binding Proteins; Heme; Hemeproteins; Models, Molecular; Oxidation-Reduction; Protein Binding; Protein Conformation; Rhodospirillum rubrum; Trans-Activators | 2018 |
CatroxMP-II: a heme-modulated fibrinogenolytic metalloproteinase isolated from Crotalus atrox venom.
Topics: Animals; Blood Coagulation; Carbon Monoxide; Crotalid Venoms; Crotalus; Fibrinogen; Heme; Kinetics; Metalloproteases | 2018 |
A novel mechanism of heme degradation to biliverdin studied by QM/MM and QM calculations.
Topics: Biliverdine; Carbon Monoxide; Heme; Heme Oxygenase (Decyclizing); Hydrogen Bonding; Hydroxylation; Iron; Ligands; Molecular Structure; Oxidation-Reduction; Oxygen; Quantum Theory; Water | 2018 |
Differential heme-mediated modulation of Deinagkistrodon, Dispholidus, Protobothrops and Pseudonaja hemotoxic venom activity in human plasma.
Topics: Animals; Blood Coagulation; Blood Coagulation Tests; Carbon Monoxide; Elapid Venoms; Elapidae; Heme; Humans | 2018 |
Ultrafast carbon monoxide photolysis and heme spin-crossover in myoglobin via nonadiabatic quantum dynamics.
Topics: Carbon Monoxide; Electrons; Heme; Iron; Ligands; Models, Theoretical; Molecular Dynamics Simulation; Myoglobin; Photolysis; Porphyrins; Protein Conformation; Vibration | 2018 |
Successful Mesoporous Silica Encapsulation of Optimally Functional EcDOS (E. coli Direct Oxygen Sensor), a Heme-based O
Topics: Biosensing Techniques; Carbon Monoxide; Enzymes, Immobilized; Escherichia coli Proteins; Heme; Oxygen; Phosphoric Diester Hydrolases; Porosity; Silicon Dioxide; Surface Properties | 2019 |
The role of redox-dependent mechanisms in heme release from hemoglobin and erythrocyte hemolysates.
Topics: Carbon Monoxide; Cyanides; Erythrocytes; Ethylmaleimide; Glucose Oxidase; Glutathione; Heme; Hemoglobins; Hemolysis; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Oxidation-Reduction; Superoxide Dismutase | 2019 |
Synthetic Iron Porphyrins for Probing the Differences in the Electronic Structures of Heme a
Topics: Carbon Monoxide; Coordination Complexes; Density Functional Theory; Heme; Iron; Metalloporphyrins; Models, Chemical; Nitric Oxide; Oxidation-Reduction | 2019 |
A Single Mutation in the Mycobacterium tuberculosis Heme-Degrading Protein, MhuD, Results in Different Products.
Topics: Bacterial Proteins; Biliverdine; Carbon Monoxide; Formaldehyde; Heme; Heme Oxygenase (Decyclizing); Models, Molecular; Mutation; Mycobacterium tuberculosis; Protein Conformation | 2019 |
Proximal and distal control for ligand binding in neuroglobin: role of the CD loop and evidence for His64 gating.
Topics: Binding Sites; Carbon Monoxide; Heme; Humans; Kinetics; Ligands; Models, Molecular; Molecular Conformation; Mutation; Neuroglobin; Protein Binding; Structure-Activity Relationship; Temperature | 2019 |
Characterization of a Carbon Monoxide-Activated Soluble Guanylate Cyclase from Chlamydomonas reinhardtii.
Topics: Algal Proteins; Carbon Dioxide; Carbon Monoxide; Chlamydomonas reinhardtii; Heme; Kinetics; Nitric Oxide; Protein Binding; Protein Multimerization; Signal Transduction; Soluble Guanylyl Cyclase; Up-Regulation | 2019 |
A spectroelectrochemical investigation of the heme-based sensor DevS from Mycobacterium tuberculosis: a redox versus oxygen sensor.
Topics: Bacterial Proteins; Biosensing Techniques; Carbon Monoxide; Cyanides; Heme; Humans; Imidazoles; Mycobacterium tuberculosis; Nitric Oxide; Oxidation-Reduction; Oxygen; Protamine Kinase; Tuberculosis | 2019 |
Interaction of the Full-Length Heme-Based CO Sensor Protein RcoM-2 with Ligands.
Topics: Bacterial Proteins; Carbon Monoxide; DNA; Escherichia coli; Fluorescence Polarization; Heme; Hemeproteins; Kinetics; Ligands; Protein Binding; Protein Interaction Domains and Motifs | 2019 |
Non-canonical transcriptional regulation of heme oxygenase in Aedes aegypti.
Topics: Aedes; Animals; Antioxidants; Biliverdine; Carbon Monoxide; Down-Regulation; Gene Expression Regulation; Heme; Heme Oxygenase (Decyclizing); Oxidative Stress; Transcription, Genetic | 2019 |
Classical and murburn explanations for acute toxicity of cyanide in aerobic respiration: A personal perspective.
Topics: Adenosine Triphosphate; Aerobiosis; Carbon Monoxide; Cell Respiration; Cyanides; Heme; Humans; Mitochondrial Membranes; Oxidative Phosphorylation; Oxygen Consumption; Reactive Oxygen Species | 2020 |
Direct observation of ligand migration within human hemoglobin at work.
Topics: Carbon Monoxide; Crystallography, X-Ray; Diffusion; Heme; Hemoglobins; Histidine; Humans; Ligands; Models, Molecular; Protein Conformation; Protein Subunits; Recombinant Fusion Proteins | 2020 |
Heme is required for carbon monoxide activation of mitochondrial BK
Topics: Boranes; Carbon Monoxide; Carbonates; Cell Line, Tumor; Heme; Humans; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Membrane Potentials; Mitochondria; N-substituted Glycines; Organometallic Compounds; Protein Binding | 2020 |
Nonbonded Atomic Contacts Drive Ultrafast Helix Motions in Myoglobin.
Topics: Carbon Monoxide; Heme; Ligands; Motion; Myoglobin | 2020 |
Heme Catabolism and Bilirubin Production in Readmitted Jaundiced Newborns.
Topics: Biomarkers; Carbon Monoxide; Female; Heme; Hemolysis; Humans; Infant, Newborn; Jaundice, Neonatal; Male; Patient Readmission; Phototherapy | 2020 |
Macrophage metabolic adaptation to heme detoxification involves CO-dependent activation of the pentose phosphate pathway.
Topics: Animals; Carbon Monoxide; Energy Metabolism; Glucose; Heme; Macrophages; Male; Mice; Mice, Inbred C57BL; Pentose Phosphate Pathway; RAW 264.7 Cells | 2020 |
Fe
Topics: Binding Sites; Calcium; Carbon Monoxide; Ferrous Compounds; HEK293 Cells; Heme; Humans; Large-Conductance Calcium-Activated Potassium Channels; Magnesium; Patch-Clamp Techniques; Photolysis | 2020 |
Development of Triggerable, Trackable, and Targetable Carbon Monoxide Releasing Molecules.
Topics: Animals; Anti-Inflammatory Agents; Carbon Monoxide; Coordination Complexes; Flavonoids; Heme; Human Umbilical Vein Endothelial Cells; Humans; Light; Macrophages; Manganese; Mice; Mitochondria; Quinolones; RAW 264.7 Cells; Ruthenium; Serum Albumin, Bovine | 2020 |
Unique Electronic Structures of the Highly Ruffled Hemes in Heme-Degrading Enzymes of
Topics: Bacterial Proteins; Carbon Monoxide; Electron Spin Resonance Spectroscopy; Heme; Humans; Hydrogen Bonding; Mixed Function Oxygenases; Oxygenases; Spectrum Analysis, Raman; Staphylococcal Infections; Staphylococcus aureus | 2020 |
Impact of breath sampling on exhaled carbon monoxide.
Topics: Adult; Breath Tests; Carbon Monoxide; Exhalation; Female; Heme; Humans; Male; Mouth; Nose; Rheology; Specimen Handling | 2020 |
Effect of the Electron Density of the Heme Fe Atom on the Nature of Fe-O
Topics: Carbon Monoxide; Electrons; Heme; Iron; Molecular Structure; Myoglobin; Oxygen; Spectroscopy, Mossbauer | 2021 |
Effect of Membrane Environment on the Ligand-Binding Properties of the Terminal Oxidase Cytochrome bd-I from Escherichia coli.
Topics: Binding Sites; Carbon Monoxide; Cell Membrane; Cytochrome b Group; Electron Transport Chain Complex Proteins; Escherichia coli; Escherichia coli Proteins; Heme; Ligands; Oxidoreductases; Protein Binding; Spectrum Analysis | 2020 |
Interplays of electron and nuclear motions along CO dissociation trajectory in myoglobin revealed by ultrafast X-rays and quantum dynamics calculations.
Topics: Animals; Carbon Monoxide; Cattle; Heme; Iron; Molecular Dynamics Simulation; Myoglobin; Protein Binding | 2021 |
Carbon monoxide exposure activates ULK1 via AMPK phosphorylation in murine embryonic fibroblasts.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Animals; Carbon Monoxide; Fibroblasts; Heme; Kelch-Like ECH-Associated Protein 1; Mice; NF-E2-Related Factor 2; Phosphorylation | 2023 |
Structure-function characterization of the mono- and diheme forms of MhuD, a noncanonical heme oxygenase from Mycobacterium tuberculosis.
Topics: Bacterial Proteins; Carbon Monoxide; Catalytic Domain; Heme; Mixed Function Oxygenases; Mycobacterium tuberculosis; Structure-Activity Relationship | 2022 |
Quaternary Structure and Deoxyribonucleic Acid-Binding Properties of the Heme-Dependent, CO-Sensing Transcriptional Regulator
Topics: Bacterial Proteins; Carbon Monoxide; DNA; Heme; Hemeproteins; Protein Binding; Transcription Factors | 2022 |
Inhibition of the carnitine acylcarnitine carrier by carbon monoxide reveals a novel mechanism of action with non-metal-containing proteins.
Topics: Carbon Monoxide; Carnitine; Heme; Membrane Transport Proteins; Mitochondria; Organometallic Compounds | 2022 |
Low-dose carbon monoxide suppresses metastatic progression of disseminated cancer cells.
Topics: Animals; Carbon Monoxide; Fibronectins; Heme; Heme Oxygenase-1; Lung Neoplasms; Male; Mice; Pancreatic Neoplasms | 2022 |
Origin of Protein Quake: Energy Waves Conducted by a Precise Mechanical Machine.
Topics: Carbon Monoxide; Diffusion; Earthquakes; Heme; Myoglobin | 2022 |
The Bonding Nature of Fe-CO Complexes in Heme Proteins.
Topics: Carbon Monoxide; Cytochrome P-450 Enzyme System; Heme; Hemeproteins; Imidazoles; Iron | 2022 |
The role of the distal cavity in carbon monoxide stabilization in the coproheme decarboxylase enzyme from C. diphtheriae.
Topics: Carbon Monoxide; Carboxy-Lyases; Corynebacterium diphtheriae; Heme; Propionates; Spectrum Analysis, Raman | 2023 |