carbon monoxide has been researched along with 3-methylcholanthrene in 107 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 103 (96.26) | 18.7374 |
| 1990's | 4 (3.74) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Autrup, H; Thurlow, BJ; Warwick, GP | 1 |
| Shigematsu, H; Yamano, S; Yoshimura, H | 1 |
| Iwasaki, K; Kato, R; Sugiura, M | 1 |
| Kahl, GF; Kahl, R; Kumaki, K; Nebert, DW | 1 |
| Aronson, I; Ivanetich, KM; Katz, ID | 1 |
| Evans, JS; Gammans, RE; Sternson, LA; Wade, AE | 1 |
| Iamkovoĭ, VI; Liakhovich, VV; Pospelova, LN; Tsyrlov, IB; Vaĭner, LM | 1 |
| Felton, JS; Levitt, RC; Nebert, DW; Robinson, JR; Thorgeirsson, SS | 1 |
| Korzeniowski, D; Levin, W; Ryan, DE; Thomas, PE | 1 |
| Krauss, P; Nehls, P; Remmer, H; Synder, R; Witmer, C | 1 |
| Alvares, AP; Cohn, JA; Kappas, A | 1 |
| Bilimoria, MH; Hogg, JC; Johnson, J; Witschi, HP | 1 |
| Flemming, K; Mönig, H; Mull, RH; Schgaguler, M; Voigt, T | 1 |
| Nambara, T; Numazawa, M; Shirao, R; Soeda, N | 1 |
| Dave, CV; Gurtoo, HL | 1 |
| Gelboin, HV; Leutz, JC; Wiebel, FJ | 1 |
| Kawalek, JC; Lu, AY | 1 |
| Wiebel, FJ | 1 |
| Busbee, D; Cantrell, E; Colvin, D; Muijsson, I; Rose, F | 1 |
| Ahokas, JT; Kärki, NT; Pelkonen, O | 1 |
| Damani, LA; Gorrod, JW | 1 |
| Kiyono, Y; Nambara, T; Numazawa, M; Soeda, N | 1 |
| Billwitz, H; Böhm, S; Butschak, G; Rein, H; Ruckpaul, K; Scheunig, G | 1 |
| Conney, AH; Kuntzman, R; Levin, W; Lu, AY; Ryan, D; West, Sk | 1 |
| Gromova, OA; Lyakhovich, VV; Tsyrlov, IB; Zakharova, NE | 1 |
| Turner, DM | 1 |
| Conney, AH; Cooper, DY; Kuntzman, R; Levin, W; Lu, AY; Rosenthal, O; Schleyer, H | 1 |
| Bockman, D; Bresnick, E; Chuang, AH; Mukhtar, H; Stoming, TA; Vaught, JB | 1 |
| Burke, MD; Prough, RA | 1 |
| Koike, M; Matsubara, T; Sugeno, K; Tochino, Y; Touchi, A | 1 |
| Huang, MT; Kawalek, J; Levin, W; Lu, AY; Ryan, D; Thomas, P; West, SB | 1 |
| Kawalek, J; Levin, L; Lu, YH; Ryan, D; West, SB | 1 |
| Cooper, DY; Rosenthal, O; Schleyer, H; Thomas, JH; Vars, HM | 1 |
| Boose, R; May, HE; Reed, DJ | 1 |
| Arcos, JC; Argus, MF; Pastor, KM; Venkatesan, N; Wu, BC | 1 |
| Cederbaum, AI; Winters, DK | 1 |
| Hayashi, S; Ishikawa, T; Murakami, K; Noshiro, M; Okuda, K; Shimosato, T | 1 |
| Iba, MM; Lang, B | 1 |
| Faustman-Watts, EM; Giachelli, CM; Juchau, MR | 1 |
| Smith, AG; Stewart, FP | 1 |
| Gram, TE; Okine, LK | 1 |
| Kuwahara, S; Mannering, GJ | 1 |
| Gangolli, S; Wright, M | 1 |
| Gielen, JE; Goujon, FM; Nebert, DW | 1 |
| Mazel, P; Shargel, L | 2 |
| Brodie, BB; Davis, DC; Gillette, JR; Jollow, DJ; Mitchell, JR; Potter, WZ | 1 |
| Fujita, T; Mannering, GJ | 1 |
| Jacobson, M; Kuntzman, R; Levin, W; Lu, AY; McCay, PB; Poyer, JL | 1 |
| Stawarz, RJ; Stitzel, RE | 1 |
| Neal, RA; Norman, BJ; Poore, RE | 1 |
| Hershberger, WK; Juchau, MR; Pedersen, MG | 1 |
| Alvares, AP; Bickers, DR; Kappas, A | 1 |
| Conney, AH; Kuntzman, R; Lu, AY; Somogyi, A; West, S | 1 |
| Fouts, JR; Juchau, MR; Mullen, JO | 1 |
| Gillette, JR; Hernandez, PH; Mazel, P | 1 |
| Gelboin, HV; Nebert, DW | 1 |
| Gigon, PL; Gillette, JR; Gram, TE | 1 |
| Prough, RA; Reed, DJ; Wittkop, JA | 2 |
| Alvares, AP; Kuntzman, R; Levin, W; Schilling, G | 3 |
| Feller, DR; Gillette, JR; Morita, M | 1 |
| Alvares, AP; Kappas, A; Mitani, F; Sassa, S | 1 |
| Van Dyke, RA; Wineman, CG | 1 |
| Lotlikar, PD; Zaleski, K | 1 |
| Matsushima, T; Weisburger, JH | 1 |
| Mannering, GJ; Shoeman, DW; Vane, FM | 1 |
| Mannering, GJ; Zampaglione, NG | 1 |
| Comai, K; Gaylor, JL | 1 |
| Berg, A; Gustafsson, JA | 1 |
| Kiese, M; Lenk, W | 2 |
| Anders, MW; Maines, MD | 1 |
| Gustafsson, JA; Ingelman-Sundberg, M | 1 |
| Hüthwohl, B; Jonen, HG; Kahl, GF; Kahl, R | 1 |
| Glover, E; Poland, A | 1 |
| Levin, W; Lu, AY | 1 |
| Alvares, AP; Conney, AH; Gommi, B; Welch, RM | 1 |
| Cinti, DL; Kraschnitz, R; Moldeus, P; Orrenius, S; Schenkman, JB | 1 |
| Alvares, A; Conney, AH; Kuntzman, R; Levin, W | 1 |
| Alvares, AP; Kuntzman, R; Levin, W | 1 |
| Hirata, K; Nakao, K; Sakamoto, Y; Wada, F | 1 |
| Daly, JW | 1 |
| Alvares, AP; Levin, W; Schilling, G | 1 |
| Ichikawa, Y; Yamano, T | 1 |
| Aust, SD; Pederson, TC | 1 |
| Conney, AH; Jacobson, M; Kuntzman, R; Levin, W | 1 |
| Mannering, GJ; Sladek, NE | 1 |
| Kuntzman, R; Levin, W | 2 |
| Grafström, R; Jones, DP; Orrenius, S | 1 |
| Lau, PP; Lu, AY; Pickett, CB; Strobel, HW | 1 |
| Fahl, WE; Gill, K; Ho, D | 1 |
| Gorrod, JW; Patterson, LH | 1 |
| Alvares, AP; Eiseman, JL; Ueng, TH | 1 |
| Abe, T; Watanabe, M | 1 |
| Iba, MM; Mannering, GJ; Nerland, DE | 1 |
| Inoue, T; Murata, T; Niwaguchi, T | 1 |
| Horie, T; Kinoshita, K; Kitada, M; Kitagawa, H; Ohno, T | 1 |
| Cumps, J; Dumont, P; Luu-The, V; Vandresse, C | 1 |
| Hollenberg, PF; Koop, DR | 1 |
| Anders, MW; Ratnayake, JH; Stevens, JL | 1 |
| Friedman, FK; Koley, AP; Markowitz, A; Robinson, RC | 1 |
| Beaune, P; Doostzadeh, J; el Kahwaji, J; Labbe, G; Leclaire, J; Loeper, J; Pessayre, D; Thal, C; Tinel, M | 1 |
| Kitada, M; Kitagawa, H; Misaizu, T; Nakamura, T; Ohmori, S; Takano, N | 1 |
107 other study(ies) available for carbon monoxide and 3-methylcholanthrene
| Article | Year |
|---|---|
The effects of the continuous administration of N,N-dimethyl-4-phenylazoaniline (DAB) on the activities and the inducibilities of some drug-metabolizing enzymes in rat liver.
Topics: Animals; Carbon Monoxide; Cerebroside-Sulfatase; Cytochrome P-450 Enzyme System; Glucuronidase; Liver; Lysosomes; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Nitrate Reductases; Oxidoreductases; Oxidoreductases, N-Demethylating; p-Dimethylaminoazobenzene; Phenobarbital; Rats | 1975 |
NADH-dependent O-deethylation of p-nitrophenetole with rabbit liver microsomes.
Topics: Animals; Carbon Monoxide; Cobalt; Copper; Cytochrome P-450 Enzyme System; Cytochromes; Ethyl Ethers; Hydrogen-Ion Concentration; Iron; Kinetics; Male; Mercury; Methylcholanthrene; Microsomes, Liver; NAD; Oxidoreductases; Oxygen Consumption; Partial Pressure; Phenobarbital; Rabbits | 1976 |
Reduction of tertiary amine N-oxides by liver microsomal cytochrome P-450.
Topics: Amines; Aniline Compounds; Animals; Binding, Competitive; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; Imipramine; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Oxides; Oxygen Consumption; Phenobarbital; Rats; Subcellular Fractions | 1976 |
Association of the Ah locus with specific changes in metyrapone and ethylisocyanide binding to mouse liver microsomes.
Topics: Animals; Binding Sites; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Cytochromes; Dithionite; Enzyme Induction; Genes, Dominant; Hydrogen-Ion Concentration; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; Mutation; Oxygenases; Phenobarbital; Protein Binding; Protein Conformation; Spectrophotometry | 1976 |
The interaction of vinyl chloride with rat hepatic microsomal cytochrome P-450 in vitro.
Topics: Animals; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Phenobarbital; Protein Binding; Rats; Spectrophotometry; Vinyl Chloride; Vinyl Compounds | 1977 |
Interaction of nitromethane with reduced hepatic microsomal cytochrome P-450.
Topics: Aniline Compounds; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dithionite; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Morphine Derivatives; Nitro Compounds; Oxidation-Reduction; Phenobarbital; Rabbits; Spectrophotometry | 1977 |
[Cytochrome P-450 catalyzed oxidation of 1-piperidinoanthraquinone].
Topics: Animals; Anthraquinones; Carbon Monoxide; Catalysis; Cytochrome P-450 Enzyme System; Deoxycholic Acid; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; NAD; NADP; Oxidation-Reduction; Phenobarbital; Piperidines; Rats; Spectrum Analysis | 1979 |
Relationship between "aromatic hydrocarbon responsiveness" and the survival times in mice treated with various drugs and environmental compounds.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Carbon Monoxide; Crosses, Genetic; Cytochromes; DNA; Environmental Pollutants; Female; Flavonoids; Hexachlorocyclohexane; Injections, Intraperitoneal; Methylcholanthrene; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Microsomes, Liver; Necrosis; Phenotype; Polychlorinated Biphenyls; Polycyclic Compounds; Pregnancy | 1975 |
Separation and characterization of highly purified forms of liver microsomal cytochrome P-450 from rats treated with polychlorinated biphenyls, phenobarbital, and 3-methylcholanthrene.
Topics: Animals; Aroclors; Carbon Monoxide; Cytochrome P-450 Enzyme System; Immunodiffusion; Male; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Oxidation-Reduction; Peptide Fragments; Phenobarbital; Polychlorinated Biphenyls; Rats; Spectrophotometry | 1979 |
Optical and electron paramagnetic resonance studies of partially purified rabbit liver cytochrome P-450.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Dithionite; Electron Spin Resonance Spectroscopy; Hexobarbital; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rabbits; Spectrum Analysis | 1975 |
On the occurrence of cytochrome P-450 and aryl hydrocarbon hydroxylase activity in rat brain.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Brain; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Dithionite; Male; Methylcholanthrene; Methylmercury Compounds; Microsomes; NAD; Rats | 1977 |
Pulmonary aryl hydrocarbon hydroxylase: tobacco smoke-exposed guinea pigs.
Topics: Animals; Aroclors; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Benzopyrenes; Carbon Monoxide; Enzyme Induction; Guinea Pigs; Hydrogen Cyanide; In Vitro Techniques; Liver; Lung; Male; Methylcholanthrene; Nicotine; Rats; Smoking; Species Specificity; Time Factors | 1977 |
Characterization of microsomal electron transport components from control, phenobarbital- and 3-methylcholanthrene-treated mice. II. Improved resolution and quantitation of major components in ammonium sulfate fractions from total liver microsomes.
Topics: Ammonium Sulfate; Animals; Carbon Monoxide; Chemical Fractionation; Cytochrome P-450 Enzyme System; Cytochromes; Electron Spin Resonance Spectroscopy; Electron Transport; Hemeproteins; In Vitro Techniques; Membrane Proteins; Methylcholanthrene; Mice; Microsomes, Liver; Molecular Weight; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Solubility | 1977 |
Properties of enzyme systems involved in the formation of catechol estrogen glutathione conjugates in rat liver microsomes.
Topics: Animals; Carbon Monoxide; Catechols; Estrogens; Glutathione; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; NAD; Oxygen Consumption; Phenobarbital; Rats; Time Factors | 1978 |
In vitro metabolic conversion of aflatoxins and benzo(alpha)pyrene to nucleic acid-binding metabolites.
Topics: Aflatoxins; Animals; Benzopyrenes; Carbon Monoxide; Cell Fractionation; DNA; Liver; Methylcholanthrene; Micrococcus; Microsomes, Liver; NADP; Nitrogen; Nucleic Acid Denaturation; Phenobarbital; Proadifen; Rats; RNA; RNA, Transfer; Spectrum Analysis; Thymus Gland; Tritium | 1975 |
Aryl hydrocarbon (benzo[a]pyrene) hydroxylase: a mixed-function oxygenase in mouse skin.
Topics: Animals; Anthracenes; Benzopyrenes; Carbon Monoxide; Enzyme Induction; Flavonoids; Injections, Intraperitoneal; Kinetics; Liver; Lung; Methylcholanthrene; Mice; Mixed Function Oxygenases; NADP; Naphthacenes; Phenanthrenes; Skin | 1975 |
Reconstituted liver microsomal enzyme system that hydroxylates drugs, other foreign compounds, and endogenous substrates. VIII. Different catalytic activities of rabbit and rat cytochromes P-448.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Cytochrome Reductases; Cytochromes; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Pharmaceutical Preparations; Proadifen; Rabbits; Rats | 1975 |
Metabolism of monohydroxybenzo(a)pyrenes by rat liver microsomes and mammalian cells in culture.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Cells, Cultured; Chromatography; Cricetinae; Embryo, Mammalian; Flavonoids; Hydroxylation; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Rats; Spectrometry, Fluorescence; Tritium | 1975 |
Induction of aryl hydrocarbon hydroxylase in Ambystoma tigrinum.
Topics: Ambystoma; Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Methylcholanthrene; Mice; Microsomes, Liver; Organ Culture Techniques; Protein Binding; Species Specificity; Spectrophotometry; Time Factors | 1975 |
Characterization of benzo(a)pyrene hydroxylase of trout liver.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Benzopyrenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Proadifen; Rats; Salmonidae; Trout | 1977 |
The effect of various potential inhibitors, activators and inducers on the N-oxidation of 3-substituted pyridines in vitro.
Topics: Animals; Carbon Monoxide; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Induction; Enzyme Inhibitors; Guinea Pigs; In Vitro Techniques; Male; Methylcholanthrene; Mice; Microsomes, Liver; Oxidation-Reduction; Phenobarbital; Pyridines; Rabbits | 1979 |
Properties of estradiol 2-hydroxylase and 2-hydroxy-3-deoxyestradiol 3-hydroxylase in rat liver.
Topics: Animals; Carbon Monoxide; Cold Temperature; Estradiol; Estrogens; Light; Male; Methylcholanthrene; Microsomes, Liver; Nitrogen; Oxygen; Phenobarbital; Rats; Steroid Hydroxylases | 1979 |
Infrared spectral studies of carbon monoxide complexes of microsomal cytochromes P-450 and P-448.
Topics: Animals; Camphor; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Rabbits; Rats; Spectrophotometry, Infrared | 1979 |
Partial purification and separation of multiple forms of cytochrome. P-450 and cytochrome P-448 from rat liver microsomes.
Topics: Animals; Benzopyrenes; Benzphetamine; Carbon Monoxide; Chromatography, DEAE-Cellulose; Cytochrome P-450 Enzyme System; Cytochromes; Epoxide Hydrolases; Ethane; Lipids; Male; Methylcholanthrene; Microsomes, Liver; Multienzyme Complexes; NADPH-Ferrihemoprotein Reductase; Naphthalenes; Nitriles; Oxidation-Reduction; Phenobarbital; Phosphatidylcholines; Rats; Spectrum Analysis; Surface-Active Agents | 1975 |
Possible mechanism of induction of liver microsomal monooxygenases by phenobarbital.
Topics: Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Oxygenases; Phenobarbital; Protein Binding; Rats; Spectrophotometry | 1976 |
The effects of some tobacco smoke constituents on foreign compound metabolism in the cat and the rat.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Atmosphere; Carbon Monoxide; Catheterization; Cats; Cotinine; Female; Femoral Vein; In Vitro Techniques; Injections, Subcutaneous; Kidney; Lung; Male; Methylcholanthrene; Microsomes; Microsomes, Liver; Nicotine; Pharmaceutical Preparations; Phenobarbital; Rats; Time Factors | 1977 |
Inhibition by CO of hepatic benzo[a]pyrene hydroxylation and its reversal by monochromatic light.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Carbon Monoxide; Kinetics; Light; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry | 1977 |
Nuclear aryl hydrocarbon hydroxylase and interaction of polycyclic hydrocarbons with nuclear components.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrenes; Carbon Monoxide; Cell Nucleus; Chromosomal Proteins, Non-Histone; Cytochrome P-450 Enzyme System; DNA; Fluorescence; Histones; Liver; Lung; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes, Liver; Polycyclic Compounds; Protein Binding; Rats | 1977 |
Some characteristics of hamster liver and lung microsomal aryl hydrocarbon (biphenyl and benzo(a)pyrene) hydroxylation reactions.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Benzopyrenes; Carbon Monoxide; Cricetinae; Cytochrome P-450 Enzyme System; Ethylmorphine-N-Demethylase; Flavonoids; Lung; Male; Mesocricetus; Methylcholanthrene; Metyrapone; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Morphine Derivatives; Naphthalenes; Oxidoreductases, N-Demethylating | 1976 |
Quantitative determination of cytochrome P-450 in rat liver homogenate.
Topics: Aniline Hydroxylase; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Dithionite; Hemoglobins; Indicators and Reagents; Liver; Male; Methylcholanthrene; Phenobarbital; Protein Binding; Rats; Spectrophotometry | 1976 |
Multiplicity of liver microsomal cytochrome P-450: separation, purification and characterization.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Methylcholanthrene; Mice; Microsomes, Liver; Phenobarbital; Protein Binding; Rabbits; Rats; Species Specificity | 1976 |
Highly purified cytochrome P-448 and P=450 from rat liver microsomes.
Topics: Animals; Benzopyrenes; Benzphetamine; Carbon Monoxide; Chromatography, DEAE-Cellulose; Chromatography, Ion Exchange; Cytochrome P-450 Enzyme System; Cytochromes; Enzyme Induction; Methylcholanthrene; Microsomes, Liver; Molecular Weight; Oxidation-Reduction; Phenobarbital; Rats; Spectrophotometry | 1975 |
Comparison of the induction course, biophysical chemical interactions and photochemical action spectra of phenobarbital and 3-methylcholanthrene induce hepatic microsomal P-450.
Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Carbon Monoxide; Codeine; Cytochrome P-450 Enzyme System; Enzyme Induction; Hexobarbital; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Phenobarbital; Photochemistry; Polycyclic Compounds; Proadifen; Rats; Spectrum Analysis; Time Factors | 1975 |
Microsomal monooxygenation of the carcinostatic 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea. Synthesis and identification of cis and trans monohydroxylated products.
Topics: Animals; Antineoplastic Agents; Carbon Monoxide; Hydroxylation; Lomustine; Male; Methylcholanthrene; Microsomes, Liver; Nitrosourea Compounds; Oxidation-Reduction; Phenobarbital; Rats; Stereoisomerism | 1975 |
Dimethylnitrosamine-demethylase: absence of increased enzyme catabolism and multiplicity of effector sites in repression. Hemoprotein involvement.
Topics: Animals; Carbon Monoxide; Caseins; Cytochrome P-450 Enzyme System; Dietary Proteins; Dimethylnitrosamine; Enzyme Repression; Hemeproteins; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Nitrosamines; Oxidoreductases, N-Demethylating; Phenobarbital; Rats | 1976 |
Oxidation of glycerol to formaldehyde by rat liver microsomes. Effects of cytochrome P-450 inducing agents.
Topics: Acetone; Aldehyde Oxidoreductases; Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Fomepizole; Formaldehyde; Glycerol; Isoenzymes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NAD; Oxidation-Reduction; Phenobarbital; Pyrazoles; Rats; Rats, Inbred Strains | 1990 |
Aryl hydrocarbon hydroxylase activity in rat submandibular glands.
Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Carbon Monoxide; Cytochrome P-450 Enzyme System; Male; Methylcholanthrene; Metyrapone; NADH Dehydrogenase; NADPH-Ferrihemoprotein Reductase; Oxygenases; Proadifen; Rats; Rats, Inbred Strains; Submandibular Gland; Time Factors | 1986 |
Stimulation of the conjugation of lipid dienes in hepatic microsomes by 3,3'-dichlorobenzidine.
Topics: 3,3'-Dichlorobenzidine; Animals; Benzidines; Carbon Monoxide; Cytochrome P-450 Enzyme System; Lipid Metabolism; Lipid Peroxides; Male; Malondialdehyde; Methylcholanthrene; Microsomes, Liver; NADP; Nitrogen; Rats; Rats, Inbred Strains | 1988 |
Carbon monoxide inhibits monooxygenation by the conceptus and embryotoxic effects of proteratogens in vitro.
Topics: 2-Acetylaminofluorene; Animals; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Embryo, Mammalian; Female; In Vitro Techniques; Methylcholanthrene; Oxidation-Reduction; Oxygenases; Pregnancy; Rats; Teratogens | 1986 |
Metabolism of the "mixed" cytochrome P-450 inducer hexachlorobenzene by rat liver microsomes.
Topics: Acetylcysteine; Aroclors; Carbon Monoxide; Chlorobenzenes; Chlorodiphenyl (54% Chlorine); Cytochrome P-450 Enzyme System; Ellipticines; Enzyme Induction; Female; Gas Chromatography-Mass Spectrometry; Glutathione; Hexachlorobenzene; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Molecular Weight; NADP; Pentachlorophenol; Phenobarbital; Polychlorinated Dibenzodioxins; Proadifen; Safrole | 1986 |
In vitro studies on the metabolism and covalent binding of [14C]1,1-dichloroethylene by mouse liver, kidney and lung.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dichloroethylenes; Enzyme Induction; Glutathione; Hot Temperature; Hydrocarbons, Chlorinated; In Vitro Techniques; Kidney; Liver; Lung; Methylcholanthrene; Mice; Mice, Inbred C57BL; NADP; Phenobarbital; Piperonyl Butoxide; Pregnenolone Carbonitrile; Proadifen; Subcellular Fractions | 1986 |
Evidence for a predominantly NADH-dependent O-dealkylating system in rat hepatic microsomes.
Topics: Animals; Antibodies; Benzoflavones; Carbon Monoxide; Cobalt; Cyanides; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochrome-B(5) Reductase; Cytochromes b5; Dealkylation; Electron Transport; Ethylmorphine; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Male; Manganese; Methylcholanthrene; Microsomes, Liver; NAD; NADP; NADPH-Ferrihemoprotein Reductase; Nitrobenzenes; Oxygen; Partial Pressure; Phenobarbital; Proadifen; Rats | 1985 |
The histochemical demonstration of aniline hydroxylase activity in rat liver.
Topics: Acetone; Aniline Compounds; Animals; Carbon Monoxide; Cyanides; Diazonium Compounds; Ethanol; Female; Formaldehyde; Histocytochemistry; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Nitrogen; Phenobarbital; Phenols; Rats; Staining and Labeling; Time Factors | 1971 |
Genetic regulation of aryl hydrocarbon hydroxylase induction. II. Simple Mendelian expression in mouse tissues in vivo.
Topics: Aging; Animals; Benzopyrenes; Carbon Monoxide; Crosses, Genetic; Cytochromes; Enzyme Induction; Female; Genotype; Hydrogen-Ion Concentration; Kidney; Liver; Male; Methylcholanthrene; Mice; Mice, Inbred Strains; Microsomes; Microsomes, Liver; Mixed Function Oxygenases; Molecular Biology; Oxygenases; Phenobarbital; Phenotype; Polycyclic Compounds; Pregnancy | 1972 |
Effect of riboflavin deficiency on phenobarbital and 3-methylcholanthrene induction of microsomal drug-metabolizing enzymes of the rat.
Topics: Aminopyrine N-Demethylase; Animals; Azo Compounds; Benzopyrenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Diet; Enzyme Induction; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; NADP; Nitrogen; Oxidoreductases; Phenobarbital; Rats; Riboflavin Deficiency | 1973 |
Acetaminophen-induced hepatic necrosis. 3. Cytochrome P-450-mediated covalent binding in vitro.
Topics: Acetaminophen; Animals; Caffeine; Carbon Monoxide; Carbon Radioisotopes; Chemical and Drug Induced Liver Injury; Cobalt; Cyanides; Cytochrome P-450 Enzyme System; Fluorenes; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Necrosis; Phenobarbital; Piperonyl Butoxide; Protein Binding; Rats; Time Factors; Tritium | 1973 |
Electron transport components of hepatic microsomes. Solubilization, resolution, and recombination to reconstitute aniline hydroxylase activity.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Chloromercuribenzoates; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Cytochromes; Electron Transport; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; NAD; NADP; Oxidation-Reduction; Phenobarbital; Rats; Solubility; Structure-Activity Relationship; Vitamin K | 1973 |
Lipid peroxidation and the degradation of cytochrome P-450 heme.
Topics: Aminopyrine; Animals; Benzopyrenes; Benzphetamine; Carbon Monoxide; Chromatography, Paper; Chromatography, Thin Layer; Cytochrome P-450 Enzyme System; Levulinic Acids; Lipid Metabolism; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidation-Reduction; Pentobarbital; Peroxidases; Phenobarbital; Protein Binding; Rats; Secobarbital; Spectrophotometry; Time Factors; Tritium | 1973 |
Factors influencing the microsomal metabolism of 3H-reserpine.
Topics: Animals; Benzoates; Biotransformation; Carbon Monoxide; Cats; Chromatography, Thin Layer; Depression, Chemical; Dogs; Enzyme Induction; Female; Formaldehyde; Guinea Pigs; Hydrogen-Ion Concentration; Hydrolysis; Liver; Male; Methylcholanthrene; Microsomes, Liver; NAD; NADH, NADPH Oxidoreductases; NADP; Phenobarbital; Proadifen; Rats; Reserpine; Stimulation, Chemical; Temperature | 1974 |
Studies of the binding of sulfur released in the mixed-function oxidase-catalyzed metabolism of diethyl p-nitrophenyl phosphorothionate(parathion) to diethyl p-nitrophenyl phosphate (paraoxon).
Topics: Animals; Benzphetamine; Carbon Monoxide; Carbon Radioisotopes; Cytochrome P-450 Enzyme System; Dealkylation; Esterases; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxidoreductases; Paraoxon; Parathion; Phenobarbital; Solvents; Sulfur; Sulfur Radioisotopes | 1974 |
Metabolism of 3,4-benzpyrene in rainbow trout (Salmo gairdneri).
Topics: Animals; Benzopyrenes; Biotransformation; Carbon Monoxide; Gills; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney; Kinetics; Liver; Methylcholanthrene; Mixed Function Oxygenases; Muscles; Myocardium; NADP; Nitrogen; Proteins; Salmonidae; Temperature; Trout | 1974 |
Polychlorinated biphenyls: a new type of inducer of cytochrome P-448 in the liver.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Dactinomycin; Enzyme Induction; Ligands; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; Nitriles; Oxidoreductases, N-Demethylating; Phenobarbital; Polychlorinated Biphenyls; Rats; Spectrophotometry; Stimulation, Chemical | 1973 |
Pregnenolone-16 -carbonitrile: a new type of inducer of drug-metabolizing enzymes.
Topics: Aminopyrine N-Demethylase; Animals; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochrome c Group; Cytochrome P-450 Enzyme System; Enzyme Induction; Female; Liver; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Morphinans; Nitriles; Organ Size; Oxidoreductases; Oxidoreductases, N-Demethylating; Phenobarbital; Pregnenolone; Rats; Spectrophotometry | 1972 |
Studies of 3,4-benzpyrene, 3-methylcholanthrene, chlordane, and methyltestosterone as stimulators of hepatic microsomal enzyme systems in the rat.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Chlordan; In Vitro Techniques; Liver; Methylcholanthrene; Methyltestosterone; Microsomes; Mixed Function Oxygenases; NADP; Oxidoreductases; Rats; Subcellular Fractions; Zoxazolamine | 1966 |
Studies on the mechanism of action of mammalian hepatic azoreductase. II. The effects of phenobarbital and 3-methylcholanthrene on carbon monoxide sensitive and insensitive azoreductase activities.
Topics: Animals; Azo Compounds; Carbon Monoxide; Cytochromes; Female; Lipase; Liver; Methylcholanthrene; Microsomes; NADP; Organ Size; Oxidoreductases; Phenobarbital; Rats; Tetrazolium Salts | 1967 |
Substrate-inducible microsomal aryl hydroxylase in mammalian cell culture. I. Assay and properties of induced enzyme.
Topics: Animals; Benz(a)Anthracenes; Benzopyrenes; Calcium; Carbon Monoxide; Carcinogens; Cricetinae; Culture Techniques; Edetic Acid; Enzyme Induction; Female; Fetus; Fluorescence; Hot Temperature; Hydrogen-Ion Concentration; Kinetics; Magnesium; Manganese; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; NADP; Oxygen; Spectrum Analysis; Trypsin | 1968 |
Studies on the rate of reduction of hepatic microsomal cytochrome P-450 by reduced nicotinamide adenine dinucleotide phosphate: effect of drug substrates.
Topics: Aminopyrine; Aniline Compounds; Animals; Carbon Monoxide; Cytochromes; Ethylamines; Female; Hexobarbital; Imipramine; In Vitro Techniques; Kinetics; Liver; Male; Methylcholanthrene; Microsomes; Morphinans; NADP; Niacinamide; Oxidation-Reduction; Proadifen; Rats; Sex Factors; Spectrophotometry; Time Factors; Valerates | 1969 |
Oxidative demethylation of N-methylhydrazines by rat liver microsomes.
Topics: Animals; Azo Compounds; Bile Acids and Salts; Carbon Monoxide; Cytochromes; Formaldehyde; Hot Temperature; Hydrazines; In Vitro Techniques; Lipase; Methylcholanthrene; Microsomes, Liver; NADP; Oxygen Consumption; Pancreatic Juice; Phenobarbital; Proadifen; Rats | 1969 |
Inability of substrates to alter the carbon monoxide and ethyl isocyanide difference spectra of microsomal hemoprotein.
Topics: Aniline Compounds; Animals; Benzopyrenes; Carbon Monoxide; Chromatography, Thin Layer; Cyanides; Cytochromes; Male; Methylcholanthrene; Microsomes, Liver; NADP; Rats; Spectrophotometry | 1971 |
Enzymatic reduction of niridazole by rat liver microsomes.
Topics: Aerobiosis; Animals; Anthelmintics; Carbon Monoxide; Chemical Precipitation; Chromatography, Gas; Cytochromes; Guinea Pigs; Hydroxylamines; Imidazoles; Ketones; Lipase; Liver; Male; Mass Spectrometry; Methylcholanthrene; Mice; Microsomes, Liver; NAD; NADP; Nitro Compounds; Nitrogen; Oxidation-Reduction; Oxidoreductases; Oxygen; Pancreatic Juice; Phenobarbital; Quaternary Ammonium Compounds; Rabbits; Rats; Species Specificity; Spectrophotometry; Sulfates; Tetrazolium Salts; Thiazoles | 1971 |
Preparation and properties of a solubilized form of cytochrome P-450 from chick embryo liver microsomes.
Topics: Acetamides; Allyl Compounds; Animals; Bacillus subtilis; Carbon Monoxide; Cell Fractionation; Chick Embryo; Cytochromes; Depression, Chemical; Detergents; Etiocholanolone; Female; Flavins; Heme; Ketosteroids; Liver; Methods; Methylcholanthrene; Microsomes, Liver; NAD; NADP; Nitrogen; Oxidoreductases; Peptide Hydrolases; Phenobarbital; Pregnanes; Rats; Solubility; Spectrophotometry; Stimulation, Chemical | 1971 |
Influence of 2,4-dichloro-6-phenoxyethyl-amine (DPEA) and -diethylaminoethyl diphenylpropylacetate (SKF-525A) on hepatic microsomal azoreductase activity from phenobarbital or 3-methylcholanthrene induced rats.
Topics: Animals; Azo Compounds; Carbon Monoxide; Chlorine; Cytochromes; Enzyme Activation; Enzyme Induction; Ethylamines; Flavin Mononucleotide; Male; Methylcholanthrene; Microsomes, Liver; NADP; Naphthalenes; Nitrogen; Oxidoreductases; Phenobarbital; Phenols; Proadifen; Rats; Rats, Inbred Strains; Sulfonamides; Sulfonic Acids | 1972 |
Enzymatic dechlorination. Dechlorination of chloroethanes and propanes in vitro.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Chlorine; Enzyme Induction; Hydrocarbons, Halogenated; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; NADP; Oxygen; Phenobarbital; Radioisotopes; Rats; Ultracentrifugation | 1971 |
Inhibitory effect of carbon monoxide on the N- and ring-hydroxylation of 2-acetamidofluorene by hamster hepatic microsomal preparations.
Topics: 2-Acetylaminofluorene; Animals; Carbon Dioxide; Carbon Monoxide; Cricetinae; Cytochrome P-450 Enzyme System; Fluorenes; Hydroxylation; In Vitro Techniques; Injections, Intraperitoneal; Male; Methylcholanthrene; Microsomes, Liver | 1974 |
Effect of carbon monoxide or of 3-aminotriazole on C-and N-hydroxylation of the carcinogen N-2-fluorenylacetamide by liver microsomes of hamsters pretreated with 3-methylcholanthrene.
Topics: Acetamides; Animals; Body Weight; Carbon Isotopes; Carbon Monoxide; Carcinogens; Chromatography, Paper; Cricetinae; Cytochrome P-450 Enzyme System; Fluorenes; Herbicides; Hydroxylation; Liver; Male; Methylcholanthrene; Microsomes, Liver; Organ Size; Triazoles | 1972 |
Induction of drug metabolism. VII. Differences in P-420 hemoproteins from untreated and 3-methylcholanthrene-treated rats.
Topics: Animals; Biotransformation; Blood Proteins; Carbon Monoxide; Centrifugation, Density Gradient; Cytochromes; Electrophoresis, Disc; Heme; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Pharmaceutical Preparations; Rats; Sucrose; Time Factors; Tritium | 1973 |
Properties of benzpyrene hydroxylase in the liver, intestinal mucosa and adrenal of untreated and 3-methylcholanthrene-treated rats.
Topics: Adrenal Glands; Animals; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochrome P-450 Enzyme System; Enzyme Induction; In Vitro Techniques; Intestinal Mucosa; Kinetics; Liver; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Rats | 1973 |
Existence and separation of three forms of cytochrome P-450 from rat liver microsomes.
Topics: Amines; Animals; Carbon Isotopes; Carbon Monoxide; Chromatography, DEAE-Cellulose; Cyanides; Cytochrome P-450 Enzyme System; Cytochromes; Deoxycholic Acid; Enzyme Induction; Ethanol; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Solubility; Spectrophotometry; Subtilisins | 1973 |
Regulation of hydroxylation of 5 alpha-androstane-3 beta, 17 beta-diol in liver microsomes from male and female rats.
Topics: Androstanes; Animals; Carbon Isotopes; Carbon Monoxide; Castration; Chromatography, Gas; Chromatography, Gel; Chromatography, Thin Layer; Dihydrotestosterone; Estradiol; Female; Hydroxylation; Hydroxysteroids; Male; Mass Spectrometry; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Pregnenolone; Rats; Sex Factors; Testis; Testosterone; Time Factors | 1973 |
Omega- and (omega-1)-hydroxylation of 4-chloropropionanilide in liver microsomes of rabbits treated with phenobarbital or 3-methylcholanthrene.
Topics: Acetophenones; Anilides; Animals; Carbon Monoxide; Chlorine; Drug Storage; Female; Hydroxylation; Hypoxia; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pressure; Propionates; Rabbits; Time Factors | 1973 |
Omega- and (omega-1)-hydroxylation of 4-chloropropionanilide in liver microsomes of rabbits treated weith phenobarbital or 3-methylcholanthrene.
Topics: Acetanilides; Acetophenones; Anilides; Animals; Carbon Monoxide; Hydroxylation; In Vitro Techniques; Methylcholanthrene; Microsomes, Liver; Oxygen; Phenobarbital; Pressure; Propionates; Rabbits; Time Factors; Tissue Preservation | 1973 |
Characterization of the heme of cytochrome P-450 using gas chromatography-mass spectrometry.
Topics: Animals; Carbon Monoxide; Chromatography, Gas; Cytochrome P-450 Enzyme System; Heme; Hemoglobins; Humans; Male; Mass Spectrometry; Membranes; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Porphyrins; Rabbits; Rats; Solubility | 1973 |
Regulation and properties of a sex-specific hydroxylase system in female rat liver microsomes active on steroid sulfates. I. General characteristics.
Topics: Age Factors; Androstanes; Animals; Carbon Monoxide; Carbon Radioisotopes; Castration; Estradiol; Female; Hydroxysteroids; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pregnenolone Carbonitrile; Proadifen; Rats; Sex Factors; Steroid Hydroxylases; Sulfuric Acids; Testosterone | 1974 |
Influence of pyridine and some pyridine derivatives on spectral properties of reduced microsomes and on microsomal drug metabolizing activity.
Topics: Aminopyrine N-Demethylase; Aniline Compounds; Animals; Anisoles; Carbon Monoxide; Chemical Phenomena; Chemistry; Coenzymes; Cytochrome P-450 Enzyme System; Hydrogen-Ion Concentration; In Vitro Techniques; Ligands; Male; Methylcholanthrene; Metyrapone; Microsomes, Liver; Mixed Function Oxygenases; Pharmaceutical Preparations; Phenobarbital; Pyridines; Rats; Spectrophotometry, Ultraviolet | 1974 |
Comparison of 2,3,7,8-tetrachlorodibenzo-p-dioxin, a potent inducer of aryl hydrocarbon hydroxylase, with 3-methylcholanthrene.
Topics: Aminopyrine; Animals; Carbon Monoxide; Carbon Radioisotopes; Chick Embryo; Chlorobenzenes; Cyanides; Cytochrome P-450 Enzyme System; Cytochrome Reductases; Dioxins; Dose-Response Relationship, Drug; Enzyme Induction; Methylcholanthrene; Methyltransferases; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Microsomes, Liver; Mixed Function Oxygenases; Oxygenases; Proteins; Rats; Species Specificity; Spectrophotometry, Ultraviolet; Time Factors | 1974 |
Partial purification of cytochromes P-450 and P-448 from rat liver microsomes.
Topics: Ammonium Sulfate; Animals; Benzopyrenes; Benzphetamine; Calcium Phosphates; Carbon Monoxide; Chemical Precipitation; Cytochromes; Gels; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Spectrophotometry | 1972 |
Effect of enzyme induction on the metabolism of benzo(a)pyrene and 3'-methyl-4-monomethylaminoazobenzene in the pregnant and fetal rat.
Topics: Animals; Azo Compounds; Benzopyrenes; Carbon Monoxide; Carcinogens; Cyanides; Cytochromes; Dealkylation; Enzyme Induction; Female; Fetus; Liver; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Pregnancy; Rats; Spectrophotometry; Tritium | 1972 |
The nature of the reverse type I (modified type II) spectral change in liver microsomes.
Topics: Alcohols; Aminopyrine; Aniline Compounds; Animals; Benzopyrenes; Binding Sites; Carbon Monoxide; Cytochrome P-450 Enzyme System; Drug Synergism; Hexobarbital; Male; Methylcholanthrene; Microsomes, Liver; Oxidation-Reduction; Oxidoreductases; Phenacetin; Rabbits; Rats; Species Specificity; Spectrophotometry; Spectrophotometry, Ultraviolet | 1972 |
Chromatography of radioactive microsomal hemoproteins on diethylaminoethyl cellulose.
Topics: Animals; Carbon Isotopes; Carbon Monoxide; Chromatography, DEAE-Cellulose; Cytochromes; Heme; Kinetics; Levulinic Acids; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Proteins; Rats; Rats, Inbred Strains; Solubility; Time Factors; Tritium | 1971 |
Effects of inducers of liver microsomal enzymes on the composition of microsomal hemoprotein.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Chlordan; Cytochromes; Enzyme Induction; Heme; Hemeproteins; Hydroxylation; In Vitro Techniques; Levulinic Acids; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rats; Time Factors; Tritium | 1971 |
Participation of the microsomal electron transport system involving cytochrome P-450 in 7alpha-hydroxylation of cholesterol.
Topics: Animals; Antibodies; Biliary Fistula; Carbon Isotopes; Carbon Monoxide; Cholesterol; Cytochromes; Electron Transport; Fasting; Hydrocortisone; Male; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Phenobarbital; Proteins; Rabbits; Rats; Thyroxine | 1969 |
A simple radiometric assay for microsomal aryl hydroxylase activity.
Topics: Acetanilides; Administration, Oral; Animals; Carbon Isotopes; Carbon Monoxide; Enzyme Induction; Injections; Liver; Male; Methods; Methylcholanthrene; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Radiochemistry; Rats; Stimulation, Chemical; Sulfonamides; Time Factors; Tritium | 1970 |
Species differences in the induction of microsomal hemoproteins and 3,4-benzpyrene hydroxylase by phenobarbital and 3-methylcholanthrene.
Topics: Animals; Benzopyrenes; Blood Proteins; Carbon Monoxide; Cytochromes; Enzyme Induction; Guinea Pigs; Kinetics; Male; Methylcholanthrene; Mice; Microsomes, Liver; Mixed Function Oxygenases; Phenobarbital; Rabbits; Rats; Species Specificity; Spectrum Analysis | 1970 |
Further evidene on the nature of microsomal metabolism of procarbazine and related alkyhydrazines.
Topics: Animals; Benzoates; Carbon Monoxide; Cytochromes; Enzyme Induction; Hydrazines; Male; Methylcholanthrene; Microsomes, Liver; Nitrogen; Oxidoreductases; Oxygen; Phenobarbital; Proadifen; Rats; Sheep; Swine; Trypsin | 1970 |
Cytochrome b5 and CO-binding cytochromes in the Golgi membranes of mammalian livers.
Topics: Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Copper; Cytochromes; Golgi Apparatus; Liver; Manganese; Membranes; Metabolism; Methylcholanthrene; Microscopy, Electron; Microsomes; Phenobarbital; Proteins; Rabbits; RNA; Sodium; Spectrophotometry | 1970 |
Aminopyrine demethylase. Kinetic evidence for multiple microsomal activities.
Topics: Aminopyrine; Animals; Carbon Monoxide; Chromatography, Thin Layer; Cytochromes; Dealkylation; Enzyme Induction; Ethionine; Goats; Isoenzymes; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenobarbital; Proadifen; Rats; Spectrophotometry; Stimulation, Chemical; Sulfites | 1970 |
Alteration of the microsomal hemoprotein by 3-methylcholanthrene: effects of ethionine and actinomycin D.
Topics: Animals; Benzopyrenes; Carbon Monoxide; Cytochromes; Dactinomycin; Enzyme Induction; Ethionine; Liver; Male; Methionine; Methylcholanthrene; Microsomes; Mixed Function Oxygenases; Phenobarbital; Rats; Solubility; Spectrophotometry | 1968 |
Studies on microsomal hydroxylation and the demonstration of a new carbon monoxide binding pigment in liver microsomes.
Topics: Age Factors; Animals; Carbon Monoxide; Chemical Phenomena; Chemistry; Cytochromes; Enzyme Induction; Freezing; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Pigments, Biological; Rats; Spectrophotometry; Testosterone | 1968 |
Induction of drug metabolism. II. Qualitative differences in the microsomal N-demethylating systems stimulated by polycyclic hydrocarbons and by phenobarbital.
Topics: Animals; Benzene Derivatives; Benzopyrenes; Carbon Monoxide; Cyanides; Cytochromes; Depression, Chemical; Female; Formaldehyde; Kinetics; Liver; Male; Methylcholanthrene; Mice; Microsomes; Morphinans; Morphine; Phenobarbital; Proadifen; Rats; Sex Factors; Species Specificity; Stimulation, Chemical; Valerates | 1969 |
Biphasic decrease of radioactive hemoprotein from liver microsomal CO-binding particles. Effect of 3-methylcholanthrene.
Topics: Amino Acids; Animals; Carbon Monoxide; Cytochromes; Depression, Chemical; Heme; Levulinic Acids; Liver; Male; Methods; Methylcholanthrene; Microsomes; Protein Binding; Protein Biosynthesis; Rats; Solubility; Spectrum Analysis; Time Factors; Tritium | 1969 |
Biphasic decrease of radioactive hemoprotein from liver microsomal carbon monoxide-binding particles. Effect of phenobarbital and chlordane.
Topics: Age Factors; Animals; Carbon Monoxide; Chlordan; Cytochromes; Levulinic Acids; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Tritium | 1969 |
Quantitation of hemoproteins in rat small intestinal mucosa with identification of mitochondrial cytochrome P-450.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes; Electron Transport Complex IV; Hemeproteins; Intestinal Mucosa; Intestine, Small; Liver; Male; Methylcholanthrene; Mitochondria; Oxidation-Reduction; Rats; Spectrophotometry; Subcellular Fractions | 1980 |
Comparison of cytochromes P-450 with high activity toward benzo[a]pyrene purified from liver microsomes of beta-naphthoflavone and 3-methylcholanthrene-pretreated rats.
Topics: Animals; Benzo(a)pyrene; Benzoflavones; Benzopyrenes; beta-Naphthoflavone; Carbon Monoxide; Carcinogens; Cytochrome P-450 Enzyme System; Dithionite; Flavonoids; Immunodiffusion; Immunoelectrophoresis; Male; Methylcholanthrene; Microsomes, Liver; Rats; Substrate Specificity | 1982 |
Benz[a]anthracene and 3-methylcholanthrene induction of cytochrome P-450 in C3H/10T1/2 mouse fibroblasts. Modulating role of cytotoxic 3-methylcholanthrene metabolites.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benz(a)Anthracenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytosol; Enzyme Induction; Fibroblasts; Methylcholanthrene; Mice; Microsomes, Liver; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; Receptors, Drug | 1983 |
The metabolism of 4-substituted N-ethyl-N-methylanilines. III. Effect of various potential inhibitors, activators and inducers on alpha-C- and N-oxidation.
Topics: Aniline Compounds; Animals; Carbon Monoxide; Cricetinae; Cytochrome P-450 Enzyme System; Enzyme Activation; Enzyme Induction; Guinea Pigs; In Vitro Techniques; Male; Methylcholanthrene; Microsomes, Liver; Oxidoreductases; Phenobarbital | 1983 |
Inhibition of pulmonary cytochrome P-450 and benzo(a)pyrene hydroxylase in rabbits by polychlorinated biphenyls (PCBs).
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Benzopyrene Hydroxylase; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Lung; Male; Methylcholanthrene; Mixed Function Oxygenases; Polychlorinated Biphenyls; Rabbits; Rats | 1980 |
Genetic differences in the induction of aryl hydrocarbon hydroxylase and its components by 3-methylcholanthrene in liver and lung microsomes among four strains of guinea pigs.
Topics: Animals; Aryl Hydrocarbon Hydroxylases; Carbon Monoxide; Enzyme Induction; Guinea Pigs; In Vitro Techniques; Kinetics; Lung; Methylcholanthrene; Microsomes; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Species Specificity | 1982 |
Use of linoleic acid hydroperoxide in the determination of absolute spectra of membrane-bound cytochrome P-450.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; In Vitro Techniques; Linoleic Acids; Lipid Peroxides; Liver; Male; Membranes; Methylcholanthrene; Oxidation-Reduction; Phenobarbital; Rats | 1981 |
Effects of inducers and/or inhibitors on metabolism of lysergic acid diethylamide in rat liver microsomes.
Topics: Animals; Biotransformation; Carbon Monoxide; Enzyme Induction; Enzyme Inhibitors; In Vitro Techniques; Lysergic Acid Diethylamide; Methylcholanthrene; Microsomes, Liver; NAD; Oxygen Consumption; Phenobarbital; Proadifen; Rats | 1980 |
Studies of metabolism of tripamide, a new antihypertensive agent. II. Metabolism by the hepatic microsomal enzymes.
Topics: Aminopeptidases; Animals; Antibodies; Antihypertensive Agents; Carbon Monoxide; Cytochrome P-450 Enzyme System; Hydrolysis; Hydroxylation; In Vitro Techniques; Indoles; Male; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Phenylphosphonothioic Acid, 2-Ethyl 2-(4-Nitrophenyl) Ester; Rats | 1981 |
Production of carbon monoxide by sonication of medium containing glycerol. Effect on cytochrome P-450 reconstituted systems.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Dithionite; Glycerol; Hemoglobins; Humans; Kinetics; Methylcholanthrene; Microsomes, Liver; Phenobarbital; Rats; Sonication; Spectrophotometry | 1981 |
Liver microsomal metabolism of N-methylcarbazole: a probe for induction, inhibition, and species differences.
Topics: Animals; Benzoflavones; Carbazoles; Carbon Monoxide; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme Inhibitors; Methylcholanthrene; Metyrapone; Mice; Microsomes, Liver; NAD; NADP; Phenobarbital; Proadifen; Rabbits; Rats; Species Specificity | 1980 |
Metabolism of dihalomethanes to carbon monoxide. IV. Studies in isolated rat hepatocytes.
Topics: Animals; Carbon Monoxide; Hydrocarbons, Halogenated; In Vitro Techniques; Kinetics; Liver; Male; Methane; Methylcholanthrene; Phenobarbital; Proadifen; Rats | 1980 |
Interaction of polycyclic aromatic hydrocarbons and flavones with cytochromes P450 in the endoplasmic reticulum: effect on CO binding kinetics.
Topics: Animals; Benz(a)Anthracenes; Carbon Monoxide; Cytochrome P-450 Enzyme System; Endoplasmic Reticulum; Flavonoids; Kinetics; Male; Methylcholanthrene; Microsomes, Liver; Phenanthrenes; Photolysis; Polycyclic Compounds; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 1995 |
Administration of high doses of human recombinant interleukin-2 decreases the expression of several cytochromes P-450 in the rat.
Topics: Animals; Carbon Monoxide; Cytochrome P-450 Enzyme System; Cytochromes b5; Drug Interactions; Humans; Interleukin-2; Isoenzymes; Liver; Male; Methylcholanthrene; Microsomes, Liver; NADPH-Ferrihemoprotein Reductase; Organ Size; Phenobarbital; Rats; Rats, Sprague-Dawley; Recombinant Proteins | 1994 |
Differential role in lipid peroxidation between rat P450 1A1 and P450 1A2.
Topics: Animals; Benzene Derivatives; Carbon Monoxide; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Hydrogen Peroxide; Isoenzymes; Kinetics; Lipid Peroxidation; Male; Malondialdehyde; Methylcholanthrene; Microsomes, Liver; NADP; Rabbits; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Tetramethylphenylenediamine | 1993 |
Studies on the induction of CO-binding pigments in liver microsomes by phenobarbital and 3-methylcholanthrene.
Topics: Animals; Benzopyrene Hydroxylase; Carbon Monoxide; Carcinogens; Carrier Proteins; Ethionine; Hemeproteins; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; Methylcholanthrene; Microsomes, Liver; Nitriles; Phenobarbital; Pigments, Biological; Rats; Rats, Sprague-Dawley; Spectrophotometry | 1967 |