carbohydrazide has been researched along with hydrazine in 97 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.03) | 18.7374 |
| 1990's | 1 (1.03) | 18.2507 |
| 2000's | 17 (17.53) | 29.6817 |
| 2010's | 59 (60.82) | 24.3611 |
| 2020's | 19 (19.59) | 2.80 |
| Authors | Studies |
|---|---|
| Gianolio, DA; McLaughlin, LW | 1 |
| Cantor, CR; Reines, SA | 1 |
| Chevallet, M; Leize-Wagner, E; Luche, S; Rabilloud, T; Richert, S; Van Dorsselaer, A | 1 |
| Agrawal, AP; Asthana, SN; Chhabra, JS; Talawar, MB | 1 |
| Artico, M; Coluccia, A; De Martino, G; Di Pasquali, A; La Regina, G; Ragno, R; Silvestri, R | 1 |
| Amaral, VF; Bernardino, AM; Canto-Cavalheiro, MM; Charret, KS; Freitas, AC; Gomes, AO; Leon, LL; Machado, GM | 1 |
| Bijev, A | 1 |
| Brzezinski, B; Lewandowska, W; Przybylski, P; Schilf, W | 1 |
| Carling, RW; Chicchi, GG; Crawforth, J; Elliott, JM; Hutson, PH; Jones, AB; Kelly, S; Marwood, R; Meneses-Lorente, G; Mezzogori, E; Murray, F; Rigby, M; Royo, I; Russell, MG; Shaw, D; Sohal, B; Tsao, KL; Williams, B | 1 |
| Carling, RW; Chambers, M; Chicchi, GG; Elliott, JM; Hutson, PH; Jones, AB; MacLeod, A; Marwood, R; Meneses-Lorente, G; Mezzogori, E; Murray, F; Rigby, M; Royo, I; Russell, MG; Sohal, B; Tsao, KL; Williams, B | 1 |
| Dong, ZW; Ge, X; Meng, N; Miao, JY; Shin, DS; Xia, Y; Zhao, BX | 1 |
| Chen, H; Zhang, J; Zhang, T | 1 |
| Choudary, JA; Elsegood, MR; Khan, KM; Siddiqui, HL; Zia-ur-Rehman, M | 1 |
| Albuquerque, MG; Cabral, LM; Castro, HC; de Albuquerque, S; Dias, LR; Freitas, AC; Henriques, MG; Martins, RC; Rodrigues, CR; Vera-Divaio, MA | 1 |
| Dong, WL; Miao, JY; Wu, LL; Zhao, BX; Zheng, LW | 1 |
| Amaral, VF; Bernardino, AM; Canto-Cavalheiro, MM; Carvalho, AV; Charret, KS; Gomes, AO; Leon, L; Rodrigues, RF | 1 |
| Desmarais, S; Massé, F; Percival, MD | 1 |
| Candéa, AL; de Souza, MV; Ferreira, Mde L; Henriques, Md; Kaiser, CR; Lima, CH; Lourenço, MC; Vergara, FM | 1 |
| Duan, C; He, C; Jiao, Y; Liu, Y; Wu, X | 1 |
| Huang, H; Wang, L; Zhang, J; Zhang, T | 1 |
| Bromidge, SM; Buson, A; Carpenter, AJ; Cavanni, P; Contini, S; Corsi, M; D'Adamo, L; Dal Forno, G; Di Fabio, R; Di Francesco, C; Faggioni, F; Guery, S; Mattioli, M; Melotto, S; Mundi, C; Pavone, F; Perdona', E; Perini, B; Rinaldi, M; Sabbatini, FM; Savoia, C; St-Denis, Y; Tessari, M | 1 |
| Aboul-Fadl, T; Aboul-Wafa, O; Bin-Jubair, FA | 1 |
| Chen, YQ; Gong, AS; Lu, HJ; Qin, Q; Song, P; Tang, PC; Wang, L; Zheng, H | 1 |
| Rane, RA; Telvekar, VN | 1 |
| Colmena, I; de Los Ríos, C; Gandía, L; Ismaili, L; Marco-Contelles, J; Pudlo, M; Refouvelet, B; Rivas, L; Samadi, A; Soriano, E; Tomassoli, I | 1 |
| Abu-Hashem, AA; Badria, FA; El-Shehry, MF | 1 |
| Singh, R; Stables, JP; Tripathi, L | 1 |
| Cui, Z; Huang, Z; Li, Y; Liu, H; Liu, Y; Song, H; Wang, Q; Xiong, L; Zhao, Q | 1 |
| Barazarte, A; Camacho, J; Charris, J; Gamboa, N; Gilman, R; Rodrigues, J; Rojas, R; Vaisberg, A | 1 |
| Bezerra, FA; Candéa, AL; de Souza, MV; Ferreira, ML; Henriques, MG; Kaiser, CR; Lima, CH; Lourenço, MC | 1 |
| Bernasconi, G; Bromidge, SM; Corsi, M; Costantini, VJ; D'Adamo, L; Di Fabio, R; Di Francesco, C; Melotto, S; Mundi, C; Perdonà, E; Perini, B; Pozzan, A; Rinaldi, M; Sabbatini, FM; Savoia, C; Valerio, E; Visentini, F; Zonzini, L | 1 |
| Almeida, MC; Bello, ML; Campos, VR; Carvalho, GS; Castro, HC; Cunha, AC; de Souza, MC; Ferreira, VF; Jordão, AK; Lannes, A; Lourenco, A; Lourenco, MC; Rodrigues, CR; Sathler, PC | 1 |
| Adhikari, AV; Chowdhury, IH; Mahmood, R; Pal, NK; Row, G; Sumesh, E; Telkar, S; Thomas, KD | 1 |
| Al Jammaz, I; Al-Otaibi, B; Amer, S; Okarvi, SM | 1 |
| Huo, L; Wang, G; Xu, W; Zhang, D; Zhao, G | 1 |
| Brun, R; Diederich, F; Fischer, M; Freymond, C; Geist, JG; Illarionova, V; Kaiser, M; Mombelli, P; Röhl, F; Rottmann, M; Schweizer, WB; Siepe, I; van Zijl, AW; Witschel, MC | 1 |
| Chen, DZ; Guan, ZZ; Hong, X; Li, XW; Wang, YJ; Yu, YM | 1 |
| Bancerz, M; DaCosta, MV; Georges, MK; Youn, B | 1 |
| Al-Omar, MA; Al-Tamimi, AM; Alrashood, KA; El-Emam, AA | 1 |
| George, A; Hilborn, J; Kisiel, M; Oommen, OP; Varghese, OP; Ventura, M; Walboomers, XF | 1 |
| Halli, MB; Kinni, M; Sumathi, RB | 1 |
| Fernández-Lahore, M; Islam, T; Kuhnert, N; Nour, HF | 1 |
| Fedorova, M; Hoffmann, R; Milic, I | 1 |
| Amaral, VF; Bernardino, AM; Canto-Cavalheiro, MM; Carvalho-Pinto, CE; Charret, KS; Gomes, AO; Hottz, CF; Lagrota-Cândido, J; Leon, LL; Lira, ML; Rodrigues, RF | 1 |
| El-Sayed, NN; Mohareb, RM; Wardakhan, WW | 1 |
| Aghasadeghi, MR; Hajimahdi, Z; Zabihollahi, R; Zarghi, A | 1 |
| Hadjipavlou-Litina, D; Marco-Contelles, J; Samadi, A; Unzeta, M | 1 |
| Lv, PC; Ma, J; Sun, J; Yin, Y; Yuan, RJ; Zhu, HL | 1 |
| Mishra, L; Sinha, P; Srivastava, AK | 1 |
| Balachandran, V; Janaki, A; Nataraj, A | 1 |
| Abu Kull, ME; Brancale, A; El-Sabbagh, OI; Elshanawani, AA; Jones, AT; Kothayer, H; Shekhar, MP; Westwell, AD | 1 |
| Anslyn, EV; Barman, S; Chen, R; Codrea, V; Edupuganti, R; Kago, G; Krug, RM; Robertus, J; You, L | 1 |
| Bairwa, VK; Siddiki, AA; Telvekar, VN | 1 |
| Hodzic, A; Jednačak, T; Khinast, JG; Novak, P; Parlov, VJ; Plavec, J; Scheibelhofer, O; Sket, P | 1 |
| Jain, K; Kamboj, M; Kumar, K; Singh, DP | 1 |
| Al-Abdullah, ES; El-Emam, AA; Gaponenko, SV; Gladkov, LL; Shabunya-Klyachkovskaya, EV; Shimko, AN | 1 |
| Abd El-Dayem, NS; El Sadek, MM; Hassan, SY; Mostafa, MA; Yacout, GA | 1 |
| Cabral, LM; Carvalho-Pinto, CE; Castro, HC; Cunha, AC; da Silva, LC; Ferreira, VF; Jordão, AK; Kang, HC; Lourenço, AL; Rodrigues, CR; Sathler, PC; Vieira, MC | 1 |
| Duraikannu, A; Kuppusamy, M; Palrasu, M; Paulrasu, K; Shanmugasundaram, A; Thirunavukkarasu, B | 1 |
| Govindarasu, K; Kavitha, E; Sundaraganesan, N; Suresh, M; Syed Ali Padusha, M | 1 |
| Asadipour, A; Esfahanizadeh, M; Firoozpour, L; Foroumadi, A; Kobarfard, F; Mirfazli, SS; Shafiee, A; Tabib, K | 1 |
| Huang, Y; Li, J; Li, Y; Liu, Y; Shang, H; Song, H; Song, Y; Wang, Q; Xiao, Z; Yang, P; Zhao, S | 1 |
| Benipal, N; Chadderdon, DJ; Hu, YH; Jiang, Y; Li, W; Qi, J; Wang, H; Wei, W | 1 |
| Comin, M; da Silva, MM; de Carvalho, JE; do Vieira, MC; Duarte, TS; Foglio, MA; Formagio, AS | 1 |
| Al-Abdullah, ES; Al-Alshaikh, MA; Al-Tuwaijri, HM; El-Emam, AA; Habib, EE; Hassan, HM | 1 |
| Estrada-Soto, S; Hernández-Luis, F; Hernández-Vázquez, E; Ramírez-Espinosa, JJ; Salgado-Barrera, S | 1 |
| Ahmad, M; Anwar, M; Din, G; Hameed, S; Israr, M; Khan, SA; Shah, MA; Tahir, MN | 1 |
| Imran, S; Ismail, NH; Naz, H; Nuzar, HA; Rahim, F; Sultan, S; Taha, M; Ullah, H | 1 |
| Alam, MS; Dhulap, A; Hamid, H; Kalam, A; Khan, I; Tantray, MA | 1 |
| Cabral, LM; Castro, HC; Craik, CS; de Souza, AMT; Dias, LRS; Lourenço, AL; Mello, JFR; Muri, EMF; Rodrigues, CR; Saito, MS; Salvador, RRS; Sathler, PC; Silva, LA; Vera, MAF | 1 |
| González-Chávez, Z; Hernández-Luis, F; Jasso-Chávez, R; Melchor-Doncel de la Torre, S; Nieto-Meneses, R; Saavedra, E; Vázquez, C; Yépez-Mulia, L | 1 |
| Becnel, JJ; Bloomquist, JR; Estep, AS; Geldenhuys, WJ; Gross, AD; Kocyigit-Kaymakcioglu, B; Tabanca, N; Tok, F | 1 |
| Jachak, SM; Krishna, VS; Kumar, G; Sriram, D | 1 |
| Bayat, M; Hosseini, FS; Masoumi, M | 1 |
| A Bueno, PS; Bagatin, MC; Basso, EA; Canduri, F; F Rozada, AM; Gauze, GF; Kioshima, ÉS; Santos, JL; V Rodrigues, FA; V Seixas, FA | 1 |
| Bao, K; Guan, Q; Shi, A; Wang, H; Wang, S; Yang, M; Zhang, L; Zhang, W | 1 |
| Pham, VH; Phan, DC; Phan, TPD; Vu, BD | 1 |
| Ahmad, M; Ahmad, MN; Anjum, MN; Ashfaq, UA; Aslam, S; Mohsin, NA; Saddique, FA | 1 |
| Chen, ZL; Liang, FP; Liu, T; Meng, T; Qin, QP; Wang, K; Zou, HH | 1 |
| Hao, Q; He, M; Jiang, K; Shang, Y; Wang, J | 1 |
| Chen, K; Fang, M; Guo, K; He, F; Huang, J; Li, B; Lin, Z; Liu, S; Wu, Q; Wu, Z; Yao, J; Zeng, J | 1 |
| Du, Y; Feng, J; Jia, Y; Ju, H; Ren, X; Wei, Q; Wu, D; Xue, J; Yang, L | 1 |
| Anh, DT; Anh, LD; Dung, DTM; Hai, DTT; Hai, PT; Han, SB; Huan, LC; Ji, AY; Kang, JS; Nam, NH; Oanh, DTK; Park, EJ; Tung, TT | 1 |
| Acunha, TV; Back, DF; Chaves, OA; Iglesias, BA; Mainardi Martins, F; Roman, D | 1 |
| Abdel-Aziz, HA; Abdulla, M; Abo-Ashour, MF; Ahmad, R; Al-Khayal, K; Al-Rashood, ST; Al-Warhi, T; Alharbi, A; Ayyad, RR; El-Haggar, R; Eldehna, WM | 1 |
| Abbasi, MA; Ali Shah, SA; Aziz-Ur-Rehman, -; Rasool, S; Sattar, A; Siddiqui, SZ | 1 |
| Butkinaree, C; Eurtivong, C; Lirdprapamongkol, K; Niwetmarin, W; Ornnork, N; Ruchirawat, S; Saruengkhanphasit, R; Svasti, J | 1 |
| Bazan, NA; Chatzopoulou, M; Conole, D; Davies, KE; Davies, SG; Donald, JR; Edwards, B; Fairclough, RJ; Martínez, RF; Milner, JA; Russell, AJ; Shah, N; Squire, SE; Vuorinen, A; Wilkinson, IVL; Willis, NJ; Wilson, FX; Wynne, GM | 1 |
| Atalay-Sahar, E; Ballar-Kırmızıbayrak, P; Kocyigit-Kaymakcioglu, B; Tok, F; Yilmaz, S | 1 |
| Eze, CC; Eze, FU; Ezeokonkwo, MA; Ezugwu, JA; Okonkwo, VI; Onyeyilim, EL; Ugwu, DI; Uzoewulu, CP | 1 |
| Choudhary, MI; Iqbal, S; Khan, KM; Kiran, S; Malik, R; Perveen, S; Taha, M | 1 |
| Ahmad, M; Ashfaq, UA; Taj, S | 1 |
| Abdel-Wahab, BF; El-Hiti, GA; Gökce, H; Kariuki, BM; Şen, F; Sert, Y | 1 |
| N Mali, S; R Thorat, B; R Wagh, R; S Yamgar, R | 1 |
| Kaplancıklı, ZA; Koçyiğit-Kaymakçıoğlu, B; Özkay, Y; Sağlık, BN; Tok, F | 1 |
| Aki-Yalcin, E; Farouk, FM; Law, CSW; Muhammed, MT; Ooi, L; Ozturk, O; Yeong, KY | 1 |
| Attarroshan, M; Foroumadi, A; Iraji, A; Kabiri, M; Khoshneviszadeh, M; Kobarfard, F; Mirfazli, SS; Naghibi Bafghi, A; Reaz Sharifi Ardani, G; Rezaei, Z; Sheikhi, N | 1 |
1 review(s) available for carbohydrazide and hydrazine
| Article | Year |
|---|---|
Carbohydrazide Analogues: A Review of Synthesis and Biological Activities.
Topics: Anti-Bacterial Agents; Hydrazines; Schiff Bases; Structure-Activity Relationship | 2022 |
96 other study(ies) available for carbohydrazide and hydrazine
| Article | Year |
|---|---|
Synthesis and triplex forming properties of pyrimidine derivative containing extended functionality.
Topics: Base Pairing; Deoxycytidine; Drug Design; Hydrazines; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Nucleic Acid Conformation; Nucleic Acid Denaturation; Oligodeoxyribonucleotides; Pyrimidines; Semicarbazides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 1999 |
New fluorescent hydrazide reagents for the oxidized 3'-terminus of RNA.
Topics: Fluorescent Dyes; Hydrazines; Indicators and Reagents; Oxidation-Reduction; RNA; RNA, Bacterial; RNA, Ribosomal; RNA, Transfer | 1974 |
About the mechanism of interference of silver staining with peptide mass spectrometry.
Topics: Electrophoresis, Gel, Two-Dimensional; Formaldehyde; Hydrazines; Peptide Mapping; Peptides; Proteins; Sensitivity and Specificity; Silver Staining; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2004 |
Studies on lead-free initiators: synthesis, characterization and performance evaluation of transition metal complexes of carbohydrazide.
Topics: Cobalt; Copper; Explosions; Hazardous Substances; Hydrazines; Materials Testing; Metals, Heavy; Nickel; Perchlorates; Spectroscopy, Fourier Transform Infrared; Thermodynamics; Zinc | 2004 |
Docking and 3-D QSAR studies on indolyl aryl sulfones. Binding mode exploration at the HIV-1 reverse transcriptase non-nucleoside binding site and design of highly active N-(2-hydroxyethyl)carboxamide and N-(2-hydroxyethyl)carbohydrazide derivatives.
Topics: Binding Sites; Cells, Cultured; Drug Design; Drug Evaluation, Preclinical; HIV Reverse Transcriptase; Humans; Hydrazines; Microbial Sensitivity Tests; Models, Molecular; Nucleosides; Protein Conformation; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Software; Sulfones | 2005 |
Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N'-[(4-Y-phenyl)methylene]-1H-pyrazole-4-carbohydrazides.
Topics: Animals; Antiprotozoal Agents; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; Hydrazines; Leishmania; Leishmaniasis; Macrophages, Peritoneal; Mice; Mice, Inbred BALB C; Molecular Structure; Parasitic Sensitivity Tests; Pyrazoles; Structure-Activity Relationship | 2006 |
Synthesis and preliminary screening of carbohydrazides and hydrazones of pyrrole derivatives as potential tuberculostatics.
Topics: Antitubercular Agents; Chemical Phenomena; Chemistry, Physical; Drug Evaluation, Preclinical; Hydrazines; Hydrazones; Indicators and Reagents; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Pyrroles; Structure-Activity Relationship | 2006 |
Multinuclear magnetic resonance, electrospray ionization-mass spectroscopy, and parametric method 5 studies of a new derivative of gossypol with 2-thiophenecarbohydrazide as well as its complexes with LI+, Na+, K+, RB+, and Cs+ cations.
Topics: Cations, Monovalent; Cesium; Dimethyl Sulfoxide; Gossypol; Hydrazines; Isomerism; Lithium; Magnetic Resonance Spectroscopy; Metals; Molecular Structure; Potassium; Sodium; Spectrometry, Mass, Electrospray Ionization; Thiophenes | 2006 |
N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists II.
Topics: Administration, Oral; Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Fluorine; Hydrazines; Neurotransmitter Agents; Piperazines; Quinolines; Receptors, Neurokinin-3; Structure-Activity Relationship; Tumor Cells, Cultured | 2006 |
N',2-diphenylquinoline-4-carbohydrazide based NK3 receptor antagonists.
Topics: Administration, Oral; Animals; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Hydrazines; Neurotransmitter Agents; Quinolines; Receptors, Neurokinin-3; Structure-Activity Relationship; Tumor Cells, Cultured | 2006 |
Synthesis and structure-activity relationships of novel 1-arylmethyl-3-aryl-1H-pyrazole-5-carbohydrazide derivatives as potential agents against A549 lung cancer cells.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Crystallography, X-Ray; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrazines; Lung Neoplasms; Models, Molecular; Molecular Structure; Stereoisomerism; Structure-Activity Relationship | 2007 |
Synthesis, characterization and properties of nitrogen-rich salts of trinitrophloroglucinol.
Topics: Ammonia; Calorimetry, Differential Scanning; Gases; Guanidines; Hydrazines; Kinetics; Models, Chemical; Nitrogen; Phloroglucinol; Salts; Semicarbazides; Sensitivity and Specificity; Spectroscopy, Fourier Transform Infrared; Temperature; Tetrazoles; Thermogravimetry | 2009 |
A facile synthesis of novel biologically active 4-hydroxy-N'-(benzylidene)-2H-benzo[e][1,2]thiazine-3-carbohydrazide 1,1-dioxides.
Topics: Anti-Bacterial Agents; Hydrazines; Magnetic Resonance Spectroscopy; Models, Molecular | 2009 |
Synthesis, antichagasic in vitro evaluation, cytotoxicity assays, molecular modeling and SAR/QSAR studies of a 2-phenyl-3-(1-phenyl-1H-pyrazol-4-yl)-acrylic acid benzylidene-carbohydrazide series.
Topics: Animals; Antiprotozoal Agents; Benzylidene Compounds; Cell Death; Chagas Disease; Hydrazines; Models, Molecular; Quantitative Structure-Activity Relationship; Trypanosoma cruzi | 2009 |
Synthesis of novel substituted pyrazole-5-carbohydrazide hydrazone derivatives and discovery of a potent apoptosis inducer in A549 lung cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Crystallography, X-Ray; Humans; Hydrazines; Lung Neoplasms; Molecular Conformation; Pyrroles | 2009 |
Effect of oral treatment with pyrazole carbohydrazide derivatives against murine infection by Leishmania amazonensis.
Topics: Alanine Transaminase; Animals; Antiprotozoal Agents; Aspartate Aminotransferases; Body Weight; Creatinine; Hydrazines; Leishmania mexicana; Leishmaniasis; Lymph Nodes; Lymphocytes; Male; Mice; Mice, Inbred CBA; Molecular Structure; Neutrophils; Pyrazoles | 2009 |
Pharmacological inhibitors to identify roles of cathepsin K in cell-based studies: a comparison of available tools.
Topics: Animals; Benzamides; Biphenyl Compounds; Cathepsin K; Cathepsins; Cell Line; Cell Line, Tumor; Epoxy Compounds; Fibroblasts; Humans; Hydrazines; Mice; Molecular Structure; Piperazines; Protease Inhibitors; Rabbits; Rats | 2009 |
Synthesis and antimycobacterial activity of N'-[(E)-(monosubstituted-benzylidene)]-2-pyrazinecarbohydrazide derivatives.
Topics: Anti-Bacterial Agents; Antitubercular Agents; Benzylidene Compounds; Cell Survival; Drug Design; Humans; Hydrazines; Macrophages; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrazinamide | 2009 |
Self-assembly of cerium-based metal-organic tetrahedrons for size-selectively luminescent sensing natural saccharides.
Topics: Aldehydes; Carbohydrates; Cerium; Crystallography, X-Ray; Fluorescence; Hydrazines; Hydrogen Bonding; Molecular Conformation; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization | 2009 |
A screened hybrid density functional study on energetic complexes: cobalt, nickel and copper carbohydrazide perchlorates.
Topics: Algorithms; Cobalt; Copper; Electrochemistry; Hydrazines; Models, Molecular; Nickel; Perchlorates; Spectrophotometry, Infrared; Thermodynamics | 2010 |
Discovery process and characterization of novel carbohydrazide derivatives as potent and selective GHSR1a antagonists.
Topics: Cell Line; Drug Evaluation, Preclinical; Feeding and Eating Disorders; Humans; Hydrazines; Receptors, Ghrelin; Structure-Activity Relationship | 2010 |
Schiff bases of indoline-2,3-dione (isatin) derivatives and nalidixic acid carbohydrazide, synthesis, antitubercular activity and pharmacophoric model building.
Topics: Antitubercular Agents; Drug Design; Humans; Hydrazines; Isatin; Models, Molecular; Mycobacterium; Nalidixic Acid; Schiff Bases; Tuberculosis | 2010 |
Novel indoline-1- or 3,4-dihydroquinoline-1(2H)-substituted carbothiohydrazides as TPO receptor agonists.
Topics: Animals; Cell Line; Humans; Hydrazines; Indoles; Quinolines; Rats; Receptors, Thrombopoietin; Structure-Activity Relationship | 2010 |
Synthesis and evaluation of novel chloropyrrole molecules designed by molecular hybridization of common pharmacophores as potential antimicrobial agents.
Topics: Anti-Infective Agents; Ciprofloxacin; Drug Design; Hydrazines; Microbial Sensitivity Tests; Phenols; Pyrroles; Structure-Activity Relationship | 2010 |
Synthesis, biological assessment and molecular modeling of new dihydroquinoline-3-carboxamides and dihydroquinoline-3-carbohydrazide derivatives as cholinesterase inhibitors, and Ca channel antagonists.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Catalytic Domain; Cattle; Cholinesterase Inhibitors; Cholinesterases; Drug Design; Electrophorus; Hydrazines; Models, Molecular; Quinolines | 2011 |
Design and synthesis of novel thiophenecarbohydrazide, thienopyrazole and thienopyrimidine derivatives as antioxidant and antitumor agents.
Topics: Animals; Antineoplastic Agents; Antioxidants; Carcinoma, Ehrlich Tumor; Drug Design; Hydrazines; Mice; Pyrazoles; Pyrimidines; Rats; Thiophenes | 2010 |
Design & synthesis of N'-[substituted] pyridine-4-carbohydrazides as potential anticonvulsant agents.
Topics: Algorithms; Animals; Anticonvulsants; Cell Death; Computer Simulation; Dose-Response Relationship, Drug; Drug Design; Electroshock; Hydrazines; Mice; Molecular Structure; Neurons; Pentylenetetrazole; Pyridines; Rats; Seizures; Stereoisomerism | 2011 |
Synthesis, crystal structures, insecticidal activities, and structure--activity relationships of novel N'-tert-Butyl-N'-substituted-benzoyl-N-[di(octa)hydro]benzofuran{(2,3-dihydro)benzo[1,3]([1,4])dioxine}carbohydrazide derivatives.
Topics: Animals; Hydrazines; Insecta; Insecticides; Molecular Structure; Structure-Activity Relationship | 2011 |
Synthesis and biological evaluation of benzimidazole-5-carbohydrazide derivatives as antimalarial, cytotoxic and antitubercular agents.
Topics: Animals; Antimalarials; Antitubercular Agents; Benzimidazoles; Cell Line, Tumor; Drug Resistance, Multiple; Hemin; Hemoglobins; Humans; Hydrazines; Hydrolysis; Mice; Plasmodium | 2011 |
Synthesis and antimycobacterial evaluation of N'-(E)-heteroaromaticpyrazine-2-carbohydrazide derivatives.
Topics: Animals; Antitubercular Agents; Cell Line, Tumor; Cell Survival; Hydrazines; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrazines; Stereoisomerism | 2011 |
Azabicyclo[3.1.0]hexane-1-carbohydrazides as potent and selective GHSR1a ligands presenting a specific in vivo behavior.
Topics: Animals; Appetite Stimulants; Body Weight; Circular Dichroism; Eating; Female; Ghrelin; Hydrazines; Ligands; Molecular Structure; Rats; Rats, Sprague-Dawley; Receptors, Ghrelin; Structure-Activity Relationship | 2011 |
Synthesis, antitubercular activity, and SAR study of N-substituted-phenylamino-5-methyl-1H-1,2,3-triazole-4-carbohydrazides.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Hydrazines; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Mycobacterium tuberculosis; Stereoisomerism; Structure-Activity Relationship; Triazoles | 2011 |
Design, synthesis and docking studies of new quinoline-3-carbohydrazide derivatives as antitubercular agents.
Topics: Antitubercular Agents; Bacteria; Drug Design; Hydrazines; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Quinolines | 2011 |
Rapid synthesis and in vitro and in vivo evaluation of folic acid derivatives labeled with fluorine-18 for PET imaging of folate receptor-positive tumors.
Topics: Animals; Biological Transport; Cell Transformation, Neoplastic; Drug Stability; Female; Fluorine Radioisotopes; Folic Acid; Folic Acid Transporters; Humans; Hydrazines; KB Cells; Methotrexate; Mice; Mouth Neoplasms; Positron-Emission Tomography; Pyridines; Radiochemistry; Time Factors | 2011 |
Synthesis and cytotoxic activity of novel 3-(1H-indol-3-yl)-1H-pyrazole-5-carbohydrazide derivatives.
Topics: Antineoplastic Agents; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Humans; Hydrazines; Models, Molecular; Neoplasms; Pyrazoles; Structure-Activity Relationship | 2011 |
Identification of 1,3-diiminoisoindoline carbohydrazides as potential antimalarial candidates.
Topics: Antimalarials; Cell Line; Cell Survival; Humans; Hydrazines; Isoindoles; Malaria, Falciparum; Plasmodium falciparum; Structure-Activity Relationship | 2012 |
[Study on inhibition of NO(x) and dioxin emissions by carbohydrazide under moderate to high temperatures].
Topics: Air Pollutants; Dioxins; Hot Temperature; Hydrazines; Nitrogen Oxides; Oxidation-Reduction; Smoke | 2011 |
A hydrazine- and phosgene-free synthesis of tetrazinanones, precursors to 1,5-dialkyl-6-oxoverdazyl radicals.
Topics: Free Radicals; Hydrazines; Molecular Structure; Phosgene; Tetrazoles | 2012 |
Synthesis and antimicrobial activity of N'-heteroarylidene-1-adamantylcarbohydrazides and (±)-2-(1-adamantyl)-4-acetyl-5-[5-(4-substituted phenyl-3-isoxazolyl)]-1,3,4-oxadiazolines.
Topics: Anti-Infective Agents; Candida albicans; Gram-Positive Bacteria; Hydrazines; Isoxazoles; Microbial Sensitivity Tests; Oxadiazoles | 2012 |
Critical assessment of rhBMP-2 mediated bone induction: an in vitro and in vivo evaluation.
Topics: Aldehydes; Alkaline Phosphatase; Animals; Bone Morphogenetic Protein 2; Cell Line; Cell Proliferation; Cell Survival; Collagen; Drug Carriers; Drug Stability; Hyaluronic Acid; Hydrazines; Hydrogels; Hydrogen-Ion Concentration; Male; Mice; NIH 3T3 Cells; Osteogenesis; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Rheology; Transforming Growth Factor beta | 2012 |
Synthesis, spectroscopic characterization and biological evaluation studies of Schiff's base derived from naphthofuran-2-carbohydrazide with 8-formyl-7-hydroxy-4-methyl coumarin and its metal complexes.
Topics: Anti-Bacterial Agents; Antifungal Agents; Antioxidants; Bacteria; Bacterial Infections; Coordination Complexes; Coumarins; DNA Cleavage; Fungi; Furans; Humans; Hydrazines; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mycoses; Schiff Bases; Spectrophotometry, Infrared | 2012 |
Probing the dynamic reversibility and generation of dynamic combinatorial libraries in the presence of bacterial model oligopeptides as templating guests of tetra-carbohydrazide macrocycles using electrospray mass spectrometry.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Combinatorial Chemistry Techniques; Drug Discovery; Hydrazines; Macrocyclic Compounds; Molecular Dynamics Simulation; Oligopeptides; Spectrometry, Mass, Electrospray Ionization; Thermodynamics | 2012 |
Simultaneous detection of low and high molecular weight carbonylated compounds derived from lipid peroxidation by electrospray ionization-tandem mass spectrometry.
Topics: Aldehydes; Arachidonic Acids; Coumarins; Docosahexaenoic Acids; Hydrazines; Ketones; Linoleic Acids; Lipid Peroxidation; Molecular Weight; Oleic Acids; Oxidation-Reduction; Phosphatidylcholines; Reactive Oxygen Species; Spectrometry, Mass, Electrospray Ionization | 2013 |
The histopathological and immunological pattern of CBA mice infected with Leishmania amazonensis after treatment with pyrazole carbohydrazide derivatives.
Topics: Animals; Antibodies, Protozoan; Cytokines; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Hydrazines; Immunoglobulin G; Immunohistochemistry; Leishmania mexicana; Leishmaniasis, Cutaneous; Lymph Nodes; Lymphocytes; Macrophages; Male; Mice; Mice, Inbred CBA; Pyrazoles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Skin | 2013 |
Synthesis and anti-tumor evaluation of novel hydrazide and hydrazide-hydrazone derivatives.
Topics: Acetophenones; Antineoplastic Agents; Benzaldehydes; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Diazonium Compounds; Doxorubicin; Drug Screening Assays, Antitumor; Humans; Hydrazines; Hydrazones; MCF-7 Cells; Pyrazoles; Structure-Activity Relationship | 2013 |
Design, synthesis and docking studies of new 4-hydroxyquinoline-3-carbohydrazide derivatives as anti-HIV-1 agents.
Topics: Anti-HIV Agents; Crystallography; Drug Design; HeLa Cells; HIV-1; Humans; Hydrazines; Hydroxyquinolines; Models, Molecular | 2013 |
Analysis of the antioxidant properties of differently substituted 2- and 3-indolyl carbohydrazides and related derivatives.
Topics: Alzheimer Disease; Animals; Antioxidants; Biocatalysis; Biphenyl Compounds; Carrageenan; Edema; Female; Free Radical Scavengers; Humans; Hydrazines; Lipid Peroxidation; Lipoxygenase; Male; Molecular Structure; Oxidation-Reduction; Picrates; Rats; Rats, Inbred F344; Structure-Activity Relationship | 2013 |
Synthesis, structure and antibacterial activity of potent DNA gyrase inhibitors: N'-benzoyl-3-(4-bromophenyl)-1H-pyrazole-5-carbohydrazide derivatives.
Topics: Anti-Bacterial Agents; Hydrazines; Microbial Sensitivity Tests; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2013 |
Synthesis and characterization of bis[N'-(4-carboxybenzylidene)]-pyridine-2,6-dicarbohydrazide: colorimetric and fluorometric modulation in presence of F- ions.
Topics: Anions; Benzylidene Compounds; Colorimetry; Dimethyl Sulfoxide; Fluorine; Hydrazines; Magnetic Resonance Spectroscopy; Models, Molecular; Pyridines; Quantum Theory | 2013 |
Theoretical investigations on molecular structure, vibrational spectra, HOMO, LUMO, NBO analysis and hyperpolarizability calculations of thiophene-2-carbohydrazide.
Topics: Electrons; Hydrazines; Models, Molecular; Molecular Conformation; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Static Electricity; Thermodynamics; Thiophenes; Vibration | 2014 |
Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides.
Topics: Amides; Antineoplastic Agents; Binding Sites; Catalytic Domain; Cell Line, Tumor; Cell Survival; Drug Design; Humans; Hydrazines; MCF-7 Cells; Molecular Docking Simulation; Structure-Activity Relationship; Triazines; Ubiquitin-Conjugating Enzymes | 2013 |
Exploring naphthyl-carbohydrazides as inhibitors of influenza A viruses.
Topics: Animals; Antiviral Agents; Cell Line; Hydrazines; Influenza A virus; Orthomyxoviridae Infections; Viral Nonstructural Proteins; Virus Replication | 2014 |
Synthesis and biological evaluation of novel N' (4-aryloxybenzylidene)- 1H-benzimidazole-2 carbohydrazide derivatives as anti-tubercular agents.
Topics: Antitubercular Agents; Benzimidazoles; Humans; Hydrazines; Mycobacterium tuberculosis; Tuberculosis | 2014 |
Condensation reaction between carbohydrazide and salicylaldehyde: in-line vibrational spectroscopy monitoring and characterization of the reaction products in solution and solid state.
Topics: Aldehydes; Hydrazines; Magnetic Resonance Spectroscopy; Scattering, Small Angle; Solutions; Spectrum Analysis, Raman; Vibration; X-Ray Diffraction | 2014 |
Spectroscopic and antibacterial studies of new octaazamacrocyclic complexes derived from carbohydrazide and isatin.
Topics: Anti-Bacterial Agents; Bacteria; Hydrazines; Isatin; Macrolides | 2014 |
Vibrational spectroscopy of N'-(Adamantan-2-ylidene)thiophene-2-carbohydrazide, a potential antibacterial agent.
Topics: Anti-Bacterial Agents; Hydrazines; Models, Molecular; Molecular Structure; X-Ray Diffraction | 2014 |
Antioxidant and antitumor activities of new synthesized aromatic C-nucleoside derivatives.
Topics: Antineoplastic Agents; Antioxidants; Biphenyl Compounds; Cell Line, Tumor; Cell Survival; Humans; Hydrazines; Molecular Structure; Nucleosides; Oxadiazoles; Picrates; Structure-Activity Relationship; Thiosemicarbazones; Triazoles | 2014 |
In vitro and in vivo analysis of the antithrombotic and toxicological profile of new antiplatelets N-acylhydrazone derivatives and development of nanosystems: determination of novel NAH derivatives antiplatelet and nanotechnological approach.
Topics: Adult; Animals; Blood Coagulation; Chlorocebus aethiops; Drug Carriers; Hemolysis; Humans; Hydrazines; Lactic Acid; Mice; Nanoparticles; Nanotechnology; Platelet Aggregation; Platelet Aggregation Inhibitors; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Pulmonary Embolism; Triazoles; Vero Cells | 2014 |
Synthesis of 4-methyl-N'-(3-alkyl-2r,6c-diarylpiperidin-4-ylidene)-1,2,3-thiadiazole-5-carbohydrazides with antioxidant, antitumor and antimicrobial activities.
Topics: Anti-Infective Agents; Antineoplastic Agents; Antioxidants; Bacteria; Cell Line, Tumor; Cell Proliferation; Free Radical Scavengers; Fungi; Humans; Hydrazines; Inhibitory Concentration 50; Microbial Sensitivity Tests; Neoplasm Invasiveness | 2014 |
Synthesis, structural and spectral analysis of (E)-N'-(4-Methoxybenzylidene)pyridine-3-carbohydrazide dihydrate by density functional theory.
Topics: Electrons; Hydrazines; Models, Molecular; Molecular Conformation; Pyridines; Quantum Theory; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Static Electricity; Thermodynamics; Vibration | 2015 |
N-substituted indole carbohydrazide derivatives: synthesis and evaluation of their antiplatelet aggregation activity.
Topics: Adenosine Diphosphate; Arachidonic Acid; Blood Platelets; Collagen; Humans; Hydrazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Function Tests; Quantitative Structure-Activity Relationship | 2014 |
Design, synthesis, and antiviral, fungicidal, and insecticidal activities of tetrahydro-β-carboline-3-carbohydrazide derivatives.
Topics: Animals; Antiviral Agents; Carbolines; Drug Design; Fungi; Fungicides, Industrial; Hydrazines; Insecta; Insecticides; Structure-Activity Relationship; Tobacco Mosaic Virus | 2014 |
Metal-catalyst-free carbohydrazide fuel cells with three-dimensional graphene anodes.
Topics: Electric Power Supplies; Electrochemistry; Electrodes; Graphite; Hydrazines; Ion Exchange; Membranes, Artificial; Models, Molecular; Molecular Conformation | 2015 |
Synthesis, antiproliferative activity and molecular properties predictions of galloyl derivatives.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Gallic Acid; HT29 Cells; Humans; Hydrazines; MCF-7 Cells; Molecular Structure; Oxadiazoles | 2015 |
Synthesis, Antimicrobial and Hypoglycemic Activities of Novel N-(1-Adamantyl)carbothioamide Derivatives.
Topics: Adamantane; Animals; Anti-Bacterial Agents; Candida albicans; Diabetes Mellitus, Experimental; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydrazines; Hypoglycemic Agents; Isothiocyanates; Male; Microbial Sensitivity Tests; Rats; Rats, Sprague-Dawley; Triazoles | 2015 |
Synthesis and molecular docking of N'-arylidene-5-(4-chlorophenyl)-1-(3,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carbohydrazides as novel hypoglycemic and antioxidant dual agents.
Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Halogenation; Hydrazines; Hypoglycemic Agents; Male; Molecular Docking Simulation; Pyrazoles; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2016 |
Synthesis, characterization and biological evaluation of some 5-methylpyrazine carbohydrazide based hydrazones.
Topics: Anti-Infective Agents; Antioxidants; Carbon-13 Magnetic Resonance Spectroscopy; Crystallography, X-Ray; Drug Design; Enzyme Inhibitors; Hydrazines; Hydrazones; Mass Spectrometry; Models, Molecular; Molecular Structure; Proton Magnetic Resonance Spectroscopy; Pyrazines; Spectrophotometry, Infrared; Structure-Activity Relationship; Urease | 2016 |
Synthesis and biological evaluation of novel N-arylidenequinoline-3-carbohydrazides as potent β-glucuronidase inhibitors.
Topics: Glycoproteins; Humans; Hydrazines; Hydrogen Bonding; Inhibitory Concentration 50; Molecular Docking Simulation; Structure-Activity Relationship | 2016 |
Synthesis of benzimidazole based thiadiazole and carbohydrazide conjugates as glycogen synthase kinase-3β inhibitors with anti-depressant activity.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzimidazoles; Binding Sites; Glycogen Synthase Kinase 3 beta; Hydrazines; Hydrogen Bonding; Maze Learning; Mice; Molecular Docking Simulation; Protein Structure, Tertiary; Thiadiazoles | 2016 |
Synthesis and mechanistic evaluation of novel N'-benzylidene-carbohydrazide-1H-pyrazolo[3,4-b]pyridine derivatives as non-anionic antiplatelet agents.
Topics: Benzylidene Compounds; Blood Platelets; Dose-Response Relationship, Drug; Humans; Hydrazines; Molecular Docking Simulation; Molecular Structure; Platelet Aggregation Inhibitors; Pyrazoles; Pyridines; Structure-Activity Relationship | 2017 |
Synthesis and biological evaluation of 2-methyl-1H-benzimidazole-5-carbohydrazides derivatives as modifiers of redox homeostasis of Trypanosoma cruzi.
Topics: Animals; Benzimidazoles; Dose-Response Relationship, Drug; Homeostasis; Hydrazines; Mice; Molecular Structure; Oxidation-Reduction; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma cruzi | 2017 |
Synthesis and structure-activity relationships of carbohydrazides and 1,3,4-oxadiazole derivatives bearing an imidazolidine moiety against the yellow fever and dengue vector, Aedes aegypti.
Topics: Aedes; Animals; Female; Hydrazines; Imidazolidines; Insecticides; Larva; Oxadiazoles; Structure-Activity Relationship | 2018 |
Synthesis of carbohydrazides and carboxamides as anti-tubercular agents.
Topics: Antitubercular Agents; Caco-2 Cells; Drug Design; HEK293 Cells; Humans; Hydrazines; Microbial Sensitivity Tests; Molecular Docking Simulation; Mycobacterium tuberculosis; Structure-Activity Relationship; Tuberculosis | 2018 |
Synthesis of (E)-2-amino-N'-benzylidenehexahydroquinoline-3-carbohydrazide.
Topics: Catalysis; Chemistry Techniques, Synthetic; Green Chemistry Technology; Hydrazines | 2019 |
New 4-methoxy-naphthalene derivatives as promisor antifungal agents for paracoccidioidomycosis treatment.
Topics: Amphotericin B; Animals; Antifungal Agents; Chlorocebus aethiops; Drug Combinations; Drug Synergism; Homoserine Dehydrogenase; Hydrazines; Macrophages; Mice; Microbial Sensitivity Tests; Molecular Dynamics Simulation; Naphthalenes; Paracoccidioides; Paracoccidioidomycosis; Protein Stability; Vero Cells | 2019 |
Design, synthesis and bioevaluation of 3-oxo-6-aryl-2,3-dihydropyridazine-4-carbohydrazide derivatives as novel xanthine oxidase inhibitors.
Topics: Animals; Binding Sites; Catalytic Domain; Cattle; Drug Design; Enzyme Inhibitors; Hydrazines; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship; Xanthine Oxidase | 2019 |
Synthesis and Bioactivity of Hydrazide-Hydrazones with the 1-Adamantyl-Carbonyl Moiety.
Topics: Adamantane; Anti-Bacterial Agents; Candida albicans; Gram-Negative Bacteria; Gram-Positive Bacteria; Hydrazines; Hydrazones; Microbial Sensitivity Tests | 2019 |
Alpha-glucosidase inhibition and molecular docking studies of 1,2-benzothiazine 1,1-dioxide based carbohydrazides.
Topics: Acarbose; alpha-Glucosidases; Diabetes Mellitus; Glycoside Hydrolase Inhibitors; Humans; Hydrazines; Hypoglycemic Agents; Kinetics; Molecular Docking Simulation; Structure-Activity Relationship; Thiazines | 2019 |
Mitochondria-localizing dicarbohydrazide Ln complexes and their mechanism of in vitro anticancer activity.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Coordination Complexes; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Hydrazines; Lanthanoid Series Elements; Mitochondria; Molecular Structure; Structure-Activity Relationship | 2020 |
Discovery of heterocyclic carbohydrazide derivatives as novel selective fatty acid amide hydrolase inhibitors: design, synthesis and anti-neuroinflammatory evaluation.
Topics: Amidohydrolases; Binding Sites; Carboxylesterase; Drug Design; Enzyme Inhibitors; Humans; Hydrazines; Inhibitory Concentration 50; Interleukin-1beta; Lipopolysaccharides; Microglia; Molecular Docking Simulation; Structure-Activity Relationship; Tumor Necrosis Factor-alpha | 2020 |
Design, synthesis, and biological evaluation of 5-((8-methoxy-2-methylquinolin-4-yl)amino)-1H-indole-2-carbohydrazide derivatives as novel Nur77 modulators.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Design; Humans; Hydrazines; Kaplan-Meier Estimate; Liver Neoplasms; Mice; Molecular Docking Simulation; Nuclear Receptor Subfamily 4, Group A, Member 1; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2020 |
Etching Triangular Silver Nanoparticles by Self-generated Hydrogen Peroxide to Initiate the Response of an Electrochemiluminescence Sensing Platform.
Topics: Antigens, Neoplasm; Biosensing Techniques; Bismuth; Coordination Complexes; Electrochemical Techniques; Fluorescent Dyes; Humans; Hydrazines; Hydrogen Peroxide; Keratin-19; Limit of Detection; Luminescent Measurements; Metal Nanoparticles; Ruthenium; Silver; Vanadates | 2020 |
Design, synthesis, and evaluation of novel
Topics: Antineoplastic Agents; Apoptosis; Caspase Inhibitors; Caspases, Initiator; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Hydrazines; Isatin; Molecular Docking Simulation; Structure-Activity Relationship | 2020 |
Helical water-soluble Ni
Topics: Adipates; Azo Compounds; Coordination Complexes; Crystallography, X-Ray; DNA; Humans; Hydrazines; Ligands; Molecular Docking Simulation; Molecular Structure; Nickel; Pyridoxal; Schiff Bases; Serum Albumin, Human; Solubility; Succinates; Thiosemicarbazones; Water; X-Ray Diffraction | 2021 |
Development of 2-oindolin-3-ylidene-indole-3-carbohydrazide derivatives as novel apoptotic and anti-proliferative agents towards colorectal cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Colorectal Neoplasms; Dose-Response Relationship, Drug; Drug Development; Drug Screening Assays, Antitumor; Humans; Hydrazines; Indoles; Molecular Structure; Structure-Activity Relationship; Tumor Cells, Cultured | 2021 |
Report - Synthesis of new antibacterial agents encompassing tosyl, piperidine, propanamide and 1,3,4-oxadiazole functionalities.
Topics: Anti-Bacterial Agents; Hydrazines; Microbial Sensitivity Tests; Oxadiazoles; Piperidines; Tosyl Compounds | 2020 |
Identification of new 3-phenyl-1H-indole-2-carbohydrazide derivatives and their structure-activity relationships as potent tubulin inhibitors and anticancer agents: A combined in silico, in vitro and synthetic study.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Humans; Hydrazines; Indoles; Molecular Structure; Structure-Activity Relationship; Tubulin; Tubulin Modulators | 2021 |
Discovery and mechanism of action studies of 4,6-diphenylpyrimidine-2-carbohydrazides as utrophin modulators for the treatment of Duchenne muscular dystrophy.
Topics: Dose-Response Relationship, Drug; Drug Discovery; Humans; Hydrazines; Molecular Structure; Muscular Dystrophy, Duchenne; Pyrimidines; RNA, Messenger; Structure-Activity Relationship; Utrophin | 2021 |
Induction of Divergent Cell Death Pathways by Urea and Carbohydrazide Derivatives.
Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Endoplasmic Reticulum Stress; Humans; Hydrazines; Liver Neoplasms; Unfolded Protein Response; Urea | 2022 |
Synthesis and Evaluation of Bis-Schiff Bases of Carbohydrazide as Antioxidant and Cytotoxic Agents.
Topics: Antioxidants; Cytotoxins; Hydrazines; Schiff Bases | 2022 |
Exploring of novel 4-hydroxy-2H-benzo[e][1,2]thiazine-3-carbohydrazide 1,1-dioxide derivative as a dual inhibitor of α-glucosidase and α-amylase: Molecular docking, biochemical, enzyme kinetic and in-vivo mouse model study.
Topics: alpha-Amylases; alpha-Glucosidases; Animals; Diabetes Mellitus; Glycoside Hydrolase Inhibitors; Hydrazines; Hyperglycemia; Hypoglycemic Agents; Mice; Molecular Docking Simulation; Molecular Dynamics Simulation; Thiazines | 2022 |
Quantum Computational Investigation of (
Topics: Hydrazines; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; Quantum Theory; Solvents; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Thermodynamics; Triazoles; Vibration | 2022 |
Synthesis, Molecular docking, Antioxidant, Anti-TB, and Potent MCF-7 Anticancer Studies of Novel Aryl-carbohydrazide Analogues.
Topics: Antineoplastic Agents; Antioxidants; Hydrazines; Molecular Docking Simulation; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship | 2022 |
N-Substituted Arylidene-3-(Methylsulfonyl)-2-Oxoimidazolidine-1-Carbohydrazide as Cholinesterase Inhibitors: Design, Synthesis, and Molecular Docking Study.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Enzyme Inhibitors; Humans; Hydrazines; Molecular Docking Simulation; Molecular Structure; Structure-Activity Relationship | 2022 |
Synthesis of novel carboxamide- and carbohydrazide-benzimidazoles as selective butyrylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Alzheimer Disease; Benzimidazoles; Butyrylcholinesterase; Cholinesterase Inhibitors; Humans; Hydrazines; Molecular Docking Simulation; Structure-Activity Relationship | 2022 |
Design, synthesis, spectroscopic characterization, in vitro tyrosinase inhibition, antioxidant evaluation, in silico and kinetic studies of substituted indole-carbohydrazides.
Topics: Antioxidants; Enzyme Inhibitors; Hydrazines; Indoles; Kinetics; Molecular Docking Simulation; Molecular Structure; Monophenol Monooxygenase; Structure-Activity Relationship | 2022 |