Page last updated: 2024-08-24

carbogen and niacinamide

carbogen has been researched along with niacinamide in 115 studies

Research

Studies (115)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's63 (54.78)18.2507
2000's35 (30.43)29.6817
2010's14 (12.17)24.3611
2020's3 (2.61)2.80

Authors

AuthorsStudies
Horsman, MR2
Denekamp, J; Joiner, MC; Rojas, A1
Brown, JM1
Dennis, MF; Dische, S; Hall, DW; Hodgkiss, RJ; Joiner, MC; Rojas, A; Stratford, MR1
Aoki, DS; Chaplin, DJ; Horsman, MR1
Dische, S; Pigott, K; Saunders, MI1
de Koster, A; Grotenhuis, JA; Kaanders, JH; Keyser, A; Prick, MJ; Thijssen, HO; van der Kogel, AJ; van der Maazen, RW; Wesseling, P1
Chaplin, DJ; Horsman, MR; Khalil, AA; Nordsmark, M; Overgaard, J; Siemann, DW1
Bleehen, NM; Dennis, IF; Laurence, VM; Ward, R1
Fenton, BM1
Guichard, M; Prade, M; Thomas, CD1
Fenton, BM; Siemann, DW1
Grau, C; Horsman, MR; Overgaard, J1
Bleehen, NM; Honess, DJ1
Hoskin, PJ; Saunders, MI1
Guichard, M; Martin, LM; Thomas, CD1
Raabe, A1
Chaplin, DJ; Hill, SA; Horsman, MR; Khalil, AA; Nordsmark, M; Overgaard, J; Siemann, DW1
Denekamp, J; Dennis, M; Franzén, L; Henriksson, R; Littbrand, B; Rojas, AM; Stratford, M; Zackrisson, B1
Chaplin, DJ; Horsman, MR; Siemann, DW2
Haustermans, K; van der Kogel, AJ; van der Schueren, E; Vanacker, B1
Akaboshi, M; Akuta, K; Masunaga, S; Ono, K1
Abe, M; Masunaga, S; Ono, K1
Abe, M; Akaboshi, M; Akuta, K; Masunaga, S; Ono, K1
Guichard, M; Lartigau, E; Simon, JM1
Dennis, MF; Hodgkiss, RJ; Johns, H; Rojas, A; Stratford, MR1
Fiat, PR; Johns, H; Rojas, AM1
Brown, JM; Dorie, MJ; Menke, D1
Calvert, AS; Hirst, VK; Johns, H; Rojas, A1
Guichard, M; Hodgkiss, RJ; Stern, S1
Denekamp, J; Fowler, JF; Johns, H; Joiner, MC; Martindale, C; Rojas, A; Vojnovic, B1
Kaanders, JH; Marres, HA; Pop, LA; van Daal, WA; van der Kogel, AJ; van der Maazen, RW1
Dische, S; Saunders, M1
Abe, M; Akaboshi, M; Akuta, K; Kawai, K; Kinashi, Y; Masunaga, S; Ono, K; Suzuki, M; Takagaki, M1
Chaplin, DJ; Guichard, M; Stern, S; Thomas, CD1
Duncan, GG; Graham, P; Green, A; Marlow, C; Pickles, T; Rheaume, DE; Syndikus, I1
Denekamp, J; Waites, A1
Rojas, A1
Guichard, M; Stern, S1
Caciagli, P; Cartei, F; Colosimo, S; Danesi, R; Del Tacca, M; Ducci, F; Fatigante, L; Laddaga, M; Marini, C; Prediletto, R1
Brizel, DM; Dewhirst, MW; Dodge, RK; Hage, WD; Munley, MT; Piantadosi, CA1
Hamers, HP; Lambin, P; Menten, J; Poortmans, P1
Cladd, H; Goodchild, K; Hoskin, PJ; Phillips, H; Powell, ME; Rojas, A; Saunders, MI; Stratford, MR1
Chaplin, DJ; Lam, GK; Ohizumi, Y; Pickles, T1
Denekamp, J; Fowler, JF1
Hartmann, KA; Schneider, CJ; Sminia, P; Van der Kleij, AJ1
Brown, JM; Wouters, BG1
Chaplin, DJ; Hill, SA; Hoskin, PJ; Powell, ME; Saunders, MI1
Denekamp, J; Dennis, MF; Dische, S; Goodchild, K; Hoskin, PJ; Pigott, K; Powell, ME; Rojas, AM; Saunders, MI; Stratford, MR1
Beck-Bornholdt, HP; Krüll, A; Raabe, A; Rett, M1
Kaanders, JH; Liefers, J; Marres, HA; Pop, LA; van Daal, WA; van den Hoogen, FJ; van der Kogel, AJ1
Bernier, J; Bieri, S; Bolla, M; Denekamp, J; Dennis, MF; Hagen, F; Kocagöncü, O; Rojas, A; Stratford, MR1
Booij, J; Bosch, DA; González González, D; Hulshof, MC; Rehmann, CJ; van Royen, EA1
Horsman, MR; Knühmann, K; Sack, H; Stüben, G; Stuschke, M1
Brauers, G; Chaplin, DJ; Collingridge, DR; Edwards, B; Hill, SA; Honess, DJ; Powell, NA1
Bussink, J; Hodgkiss, RJ; Kaanders, JH; Marres, HA; Peters, JP; Rijken, PF; van der Kogel, AJ1
Brown, JM; Dorie, MJ; el-Said, A; Menke, D1
Bernier, J; Bolla, M; Denekamp, J; Greiner, R; Hulshof, M; Miralbell, R; Mirimanoff, RO; Mornex, F; Pierart, M; Rojas, AM; Storme, G; van Glabbeke, M1
Dische, S; Hoskin, PJ; Saunders, MI1
Antognoni, P; Bernier, J; Dahl, O; Denekamp, J; Hamers, H; Horiot, JC; Kaanders, J; Piérart, M; Richaud, P; Rojas, A; Trovò, M; van Glabbeke, M1
Bussink, J; Kaanders, JH; Van der Kogel, AJ2
Fenton, BM; Lord, EM; Paoni, SF1
Droller, MJ1
Antognoni, P; Bernier, J; Dahl, O; Denekamp, J; Hamers, H; Horiot, J; Minatel, E; Piérart, M; Richaud, P; Rojas, A; van Glabbeke, M1
Griffiths, JR; Howe, FA; Robinson, SP; Stubbs, M1
Bussink, J; Kaanders, JH; Strik, AM; van der Kogel, AJ1
Buchegger, F; Coucke, PA; Mirimanoff, RO; Sun, LQ1
Griffin, RJ; Park, H; Song, CW1
Braun, RD; Dewhirst, MW; Lanzen, JL; Rosner, G; Turnage, JA1
Baas, P; Oppelaar, H; Ruevekamp, M; Schouwink, H; Stewart, FA; van Veen, R1
Chiu, RK; Koritzinsky, M; Lambin, P; Landuyt, W; Nuyts, S; Theys, J; Weppler, SA; Wouters, BG1
Goodchild, K; Hill, S; Hoskin, PJ; Saunders, M; Shah, N; Sibtain, A1
Bruaset, I; Kaanders, JH; Marres, HA; Merkx, MA; Pop, LA; van den Hoogen, FJ; van der Kogel, AJ1
Griffiths, JR; Howe, FA; Hui, C; Price, NM; Robinson, SP; Rodrigues, LM; Stubbs, M1
Bussink, J; Folkes, LK; Kaanders, JH; Stratford, MR; van der Kogel, AJ1
Bussink, J; de Wilde, PC; Kaanders, JH; Ljungkvist, AS; Marres, HA; Pop, LA; Raleigh, JA; van den Hoogen, FJ; van der Kogel, AJ; Wijffels, KI1
Dewhirst, MW; Richardson, RA1
Baillet, F; Chiras, J; Delattre, JY; Hoang-Xuan, K; Mazeron, JJ; Noël, G; Simon, JM1
Horsman, MR; Overgaard, J1
Gu, W; Guo, Y; Hang, R; Li, T; Lin, J; Zhang, Y; Zheng, X1
Bussink, J; Heerschap, A; Lok, J; Punt, CJ; van Der Kogel, AJ; van Laarhoven, HW1
Bentzen, SM; Denekamp, J; Rojas, A; Stratford, MR1
Ansiaux, R; Baudelet, C; Gallez, B; Havaux, X; Jordan, BF; Macq, B1
Griffiths, JR; Jork, A; Newell, B; Nöth, U; Robinson, SP; Rodrigues, LM; Zimmermann, U1
Hoskin, PJ; Phillips, H; Rojas, AM; Saunders, MI1
Griffin, RJ; Ogawa, A; Song, CW; Williams, BW1
Bussink, J; Heerschap, A; Kaanders, JH; Lok, J; Punt, CJ; van der Kogel, AJ; van Laarhoven, HW; Verhagen, I1
Hoogsteen, IJ; Kaanders, JH; Marres, HA; Merkx, MA; Pop, LA; van den Hoogen, FJ; van der Kogel, AJ1
Aboagye, EO; Gupta, N; Hoskin, PJ; Jones, T; Kötz, B; Osman, S; Phillips, R; Price, PM; Saleem, A; Vernon, C; Wasan, H1
de Wilde, PC; Jonathan, RA; Kaanders, JH; Marres, HA; Merkx, MA; Oosterwijk, E; Peeters, W; van der Kogel, AJ; Wijffels, KI1
Hoogsteen, IJ; Kaanders, JH; Marres, HA; van der Kogel, AJ1
Chaosu, H; Chunying, S; Xiaoshen, W; Xueguan, L; Yan, F; Yongsheng, Z1
Bentzen, SM; Hoskin, PJ; Motohashi, KJ; Rojas, AM; Saunders, MI1
Hoskin, P; Rojas, A; Saunders, M1
Jones, T; Kötz, B; Price, P; Saleem, A; West, C1
Bentzen, SM; Hoskin, PJ; Rojas, AM; Saunders, MI1
Bijl, HP; Chin, A; Doornaert, PA; Janssens, GO; Kaanders, JH; Pop, LA; Terhaard, CH; van den Ende, P1
Peters, L; Rischin, D1
Bijl, HP; Bussink, J; Chin, A; de Bree, R; Doornaert, PA; Hoogsteen, IJ; Janssens, GO; Kaanders, JH; Marres, HA; Rademakers, SE; Span, PN; Terhaard, CH; van den Ende, P; van der Kogel, AJ1
Bussink, J; De Bree, R; Doornaert, PA; Hoogsteen, IJ; Kaanders, JH; Langendijk, JA; Oosterwijk, E; Rademakers, SE; Rijken, PF; Takes, R; Terhaard, CH; van den Ende, P; van der Kogel, AJ1
Agrawal, S; Choudhury, A; Denley, H; Eustace, A; Harris, AL; Hoskin, PJ; Irlam, JJ; Ord, JJ; Rojas, AM; Ryder, D; Taylor, J; West, CM1
Betts, GN; Buffa, FM; Denley, H; Eustace, A; Harris, AL; Homer, JJ; Hoskin, PJ; Irlam, JJ; Kaanders, JH; Mani, N; Miller, CJ; Rojas, AM; Span, PN; Taylor, J; West, CM1
Bussink, J; Doornaert, PA; Hoogsteen, IJ; Kaanders, JH; Langendijk, JA; Rademakers, SE; Rijken, PF; Terhaard, CH; van den Ende, P; van der Kogel, AJ1
Bijl, HP; de Jong, MA; Doornaert, PA; Janssens, GO; Kaanders, JH; Span, PN; Terhaard, CH; van Bockel, LW; van den Broek, GB; van den Ende, P; Verbist, BM1
Bijl, HP; Bussink, J; Chin, A; de Bree, R; Doornaert, PA; Hoogsteen, IJ; Janssens, GO; Kaanders, JH; Rademakers, SE; Span, PN; Takes, RP; Terhaard, CH; van den Ende, P1
Bekkers, RL; Bussink, J; Gondhowiardjo, S; Kaanders, JH; Leer, JW; Sekarutami, SM; Span, PN; van Weelden, WJ1
Horsman, MR; Wittenborn, TR1
de Jong, MA; Doornaert, PA; Janssens, GO; Kaanders, JH; Langendijk, JA; Span, PN; Takes, RP; Terhaard, CH; van den Ende, P1
Alsner, J; Buffa, FM; Choudhury, A; Denley, H; Eustace, A; Harris, AL; Hoskin, PJ; Irlam, JJ; Taylor, J; West, CML; Yang, L1
Choudhury, A; Hoskin, PJ; Irlam, J; Lane, B; Mistry, H; Song, YP; Valentine, H; West, C; Yang, L1
Aragaki, K; Choudhury, A; Dyrskjøt, L; Hoskin, PJ; Irlam-Jones, JJ; Khan, MT; Lane, B; McConkey, DJ; Pereira, RR; Valentine, HR; West, CML1
Anzela, A; Azzopardi, M; Barrett, S; Buddle, N; Hooshmand, R; Knesl, M; Min, M; Notman, A; Vignarajah, DD; Wilson, J; Woolls, H1

Reviews

7 review(s) available for carbogen and niacinamide

ArticleYear
Clinical results of hypoxic cell radiosensitisation from hyperbaric oxygen to accelerated radiotherapy, carbogen and nicotinamide.
    The British journal of cancer. Supplement, 1996, Volume: 27

    Topics: Blood Transfusion; Carbon Dioxide; Cell Hypoxia; Humans; Hyperbaric Oxygenation; Neoplasms; Niacinamide; Oxygen; Radiation-Sensitizing Agents

1996
ARCON--current status: summary of a workshop on preclinical and clinical studies.
    Acta oncologica (Stockholm, Sweden), 1997, Volume: 36, Issue:5

    Topics: Animals; Carbon Dioxide; Cell Division; Cell Hypoxia; Head and Neck Neoplasms; Humans; Neoplasm Recurrence, Local; Neoplasms; Neoplasms, Experimental; Niacinamide; Oxygen; Oxygen Consumption; Radiation-Sensitizing Agents; Radiobiology; Radiotherapy Dosage; Randomized Controlled Trials as Topic; Regional Blood Flow; Urinary Bladder Neoplasms

1997
Improvement of tumor oxygenation by mild hyperthermia.
    Radiation research, 2001, Volume: 155, Issue:4

    Topics: Animals; Carbon Dioxide; Cell Hypoxia; Combined Modality Therapy; Dogs; Humans; Hyperthermia, Induced; Mice; Mice, Inbred C3H; Neoplasms; Niacinamide; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Rats; Regional Blood Flow; Vasodilator Agents; Xenograft Model Antitumor Assays

2001
Hypoxia as a target for combined modality treatments.
    European journal of cancer (Oxford, England : 1990), 2002, Volume: 38, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Carbon Dioxide; Cell Hypoxia; Combined Modality Therapy; Gene Expression; Humans; Neoplasms; Neovascularization, Pathologic; Niacinamide; Oxygen; Prognosis; Radiation-Sensitizing Agents

2002
The importance of tumor metabolism in cancer prognosis and therapy; pre-clinical studies on rodent tumors with agents that improve tumor oxygenation.
    Advances in enzyme regulation, 2002, Volume: 42

    Topics: Animals; Blood Glucose; Carbon Dioxide; Humans; Lactic Acid; Magnetic Resonance Imaging; Neoplasms; Niacinamide; Oxygen; Phenotype; Prognosis; Rats

2002
ARCON: a novel biology-based approach in radiotherapy.
    The Lancet. Oncology, 2002, Volume: 3, Issue:12

    Topics: Animals; Carbon Dioxide; Carcinoma; Cell Cycle; Cell Hypoxia; Clinical Trials as Topic; Dose Fractionation, Radiation; Head and Neck Neoplasms; Humans; Mammary Neoplasms, Animal; Mice; Niacinamide; Oxygen; Patient Selection; Radiation-Sensitizing Agents; Radiotherapy; Urinary Bladder Neoplasms

2002
The hypoxic tumour microenvironment, patient selection and hypoxia-modifying treatments.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2007, Volume: 19, Issue:6

    Topics: Anemia; Biomarkers, Tumor; Carbon Dioxide; Cell Hypoxia; Humans; Hyperbaric Oxygenation; Neoplasms; Niacinamide; Nuclear Medicine; Oxygen; Patient Selection; Radiation Tolerance; Radiation-Sensitizing Agents; Vitamin B Complex

2007

Trials

30 trial(s) available for carbogen and niacinamide

ArticleYear
Pharmacokinetics of nicotinamide and its effect on blood pressure, pulse and body temperature in normal human volunteers.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1992, Volume: 25, Issue:1

    Topics: Administration, Oral; Adult; Blood Pressure; Body Temperature; Carbon Dioxide; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Female; Humans; Male; Niacinamide; Oxygen; Pulse; Radiation-Sensitizing Agents

1992
Tolerance of nicotinamide and carbogen with radiation therapy for glioblastoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1996, Volume: 40, Issue:3

    Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adult; Aged; Animals; Carbon Dioxide; Combined Modality Therapy; Drug Tolerance; Female; Glioblastoma; Humans; Liver; Male; Middle Aged; Niacinamide; Oxygen; Prospective Studies; Radiotherapy Dosage; Rats; Treatment Outcome

1996
Carbogen and nicotinamide in the treatment of bladder cancer with radical radiotherapy.
    British journal of cancer, 1997, Volume: 76, Issue:2

    Topics: Aged; Carbon Dioxide; Carcinoma; Chemotherapy, Adjuvant; Cohort Studies; Female; Humans; Male; Middle Aged; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Radiotherapy, Adjuvant; Treatment Outcome; Urinary Bladder Neoplasms; Urination

1997
Human tumor blood flow is enhanced by nicotinamide and carbogen breathing.
    Cancer research, 1997, Dec-01, Volume: 57, Issue:23

    Topics: Administration, Inhalation; Administration, Oral; Carbon Dioxide; Female; Humans; Laser-Doppler Flowmetry; Microcirculation; Neoplasms; Niacinamide; Oxygen; Perfusion; Regional Blood Flow

1997
Accelerated radiotherapy, carbogen and nicotinamide (ARCON) in locally advanced head and neck cancer: a feasibility study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1997, Volume: 45, Issue:2

    Topics: Administration, Oral; Aerosols; Antiemetics; Carbon Dioxide; Disease-Free Survival; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Feasibility Studies; Head and Neck Neoplasms; Humans; Metoclopramide; Nausea; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Radiotherapy, High-Energy; Vomiting

1997
Pharmacokinetics of nicotinamide in cancer patients treated with accelerated radiotherapy: the experience of the Co-operative Group of Radiotherapy of the European Organization for Research and Treatment of Cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1998, Volume: 48, Issue:2

    Topics: Administration, Oral; Area Under Curve; Carbon Dioxide; Carcinoma; Carcinoma, Non-Small-Cell Lung; Cell Hypoxia; Dose Fractionation, Radiation; Follow-Up Studies; Half-Life; Head and Neck Neoplasms; Humans; Lung Neoplasms; Nausea; Niacinamide; Oxygen; Pyridones; Radiation-Sensitizing Agents; Tablets; Time Factors; Treatment Outcome; Vomiting

1998
Lack of perfusion enhancement after administration of nicotinamide and carbogen in patients with glioblastoma: a 99mTc-HMPAO SPECT study.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1998, Volume: 48, Issue:2

    Topics: Analysis of Variance; Brain Neoplasms; Carbon Dioxide; Cell Hypoxia; Cerebrovascular Circulation; Glioblastoma; Humans; Image Enhancement; Image Processing, Computer-Assisted; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Radiopharmaceuticals; Regional Blood Flow; Technetium Tc 99m Exametazime; Tomography, Emission-Computed, Single-Photon

1998
Accelerated radiotherapy, carbogen, and nicotinamide in glioblastoma multiforme: report of European Organization for Research and Treatment of Cancer trial 22933.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1999, Volume: 17, Issue:10

    Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Brain Neoplasms; Carbon Dioxide; Cell Division; Cell Hypoxia; Dose Fractionation, Radiation; Female; Glioblastoma; Humans; Male; Middle Aged; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Survival Analysis; Treatment Outcome

1999
Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma: hyperbaric oxygen, misonidazole, and accelerated radiotherapy, carbogen, and nicotinamide.
    Cancer, 1999, Oct-01, Volume: 86, Issue:7

    Topics: Adult; Aged; Carbon Dioxide; Humans; Hyperbaric Oxygenation; Middle Aged; Misonidazole; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Radiotherapy Dosage; Urinary Bladder Neoplasms

1999
ARCON: accelerated radiotherapy with carbogen and nicotinamide in non small cell lung cancer: a phase I/II study by the EORTC.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1999, Volume: 52, Issue:2

    Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Carbon Dioxide; Carcinoma, Non-Small-Cell Lung; Dose Fractionation, Radiation; Humans; Lung Neoplasms; Middle Aged; Niacinamide; Oxygen; Pilot Projects; Radiation-Sensitizing Agents; Radiotherapy Dosage; Radiotherapy, High-Energy

1999
ARCON: accelerated radiotherapy with carbogen and nicotinamide in head and neck squamous cell carcinomas. The experience of the Co-operative group of radiotherapy of the european organization for research and treatment of cancer (EORTC).
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2000, Volume: 55, Issue:2

    Topics: Adult; Aged; Carbon Dioxide; Carcinoma, Squamous Cell; Dose Fractionation, Radiation; Head and Neck Neoplasms; Humans; Middle Aged; Niacinamide; Oxygen; Patient Compliance; Radiotherapy

2000
ARCON: experience in 215 patients with advanced head-and-neck cancer.
    International journal of radiation oncology, biology, physics, 2002, Mar-01, Volume: 52, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Dose Fractionation, Radiation; Feasibility Studies; Female; Head and Neck Neoplasms; Humans; Hypoxia; Male; Middle Aged; Niacinamide; Oxygen; Radiation Injuries; Radiation-Sensitizing Agents

2002
Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer.
    Cancer research, 2002, Dec-01, Volume: 62, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Carbon Dioxide; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Cell Hypoxia; Combined Modality Therapy; Female; Head and Neck Neoplasms; Humans; Male; Middle Aged; Neoplasm Proteins; Niacinamide; Nitroimidazoles; Oxygen; Predictive Value of Tests; Treatment Outcome

2002
Radiotherapy and chemotherapy with or without carbogen and nicotinamide in inoperable biopsy-proven glioblastoma multiforme.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2003, Volume: 67, Issue:1

    Topics: Adult; Aged; Biopsy; Brain; Brain Neoplasms; Carbon Dioxide; Chi-Square Distribution; Combined Modality Therapy; Computer Graphics; Drug Therapy, Combination; Female; Glioblastoma; Humans; Male; Middle Aged; Niacinamide; Oxygen; Proportional Hazards Models; Radiation-Sensitizing Agents; Retrospective Studies; Statistics, Nonparametric; Survival Analysis

2003
Acute and late morbidity in the treatment of advanced bladder carcinoma with accelerated radiotherapy, carbogen, and nicotinamide.
    Cancer, 2005, Jun-01, Volume: 103, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Hypoxia; Combined Modality Therapy; Disease-Free Survival; Humans; Middle Aged; Niacinamide; Oxygen; Radiotherapy, High-Energy; Survival Rate; Urinary Bladder Neoplasms

2005
Oxygen-modifying treatment with ARCON reduces the prognostic significance of hemoglobin in squamous cell carcinoma of the head and neck.
    International journal of radiation oncology, biology, physics, 2006, Jan-01, Volume: 64, Issue:1

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Head and Neck Neoplasms; Hemoglobins; Humans; Male; Middle Aged; Multivariate Analysis; Niacinamide; Oxygen; Prognosis; Radiation-Sensitizing Agents; Sex Factors; Treatment Outcome

2006
Carbogen and nicotinamide increase blood flow and 5-fluorouracil delivery but not 5-fluorouracil retention in colorectal cancer metastases in patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, May-15, Volume: 12, Issue:10

    Topics: Administration, Inhalation; Administration, Oral; Aged; Antimetabolites, Antineoplastic; Carbon Dioxide; Colorectal Neoplasms; Drug Interactions; Female; Fluorouracil; Humans; Liver Neoplasms; Male; Middle Aged; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Regional Blood Flow; Tissue Distribution; Vitamin B Complex

2006
Carbogen and nicotinamide in locally advanced bladder cancer: early results of a phase-III randomized trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2009, Volume: 91, Issue:1

    Topics: Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma, Transitional Cell; Dose Fractionation, Radiation; Female; Humans; Male; Middle Aged; Neoplasm Invasiveness; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Radiotherapy Dosage; Treatment Outcome; Urinary Bladder Neoplasms

2009
Accelerated radiotherapy, carbogen, and nicotinamide (ARCON) in the treatment of advanced bladder cancer: mature results of a Phase II nonrandomized study.
    International journal of radiation oncology, biology, physics, 2009, Apr-01, Volume: 73, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma in Situ; Cystectomy; Dose Fractionation, Radiation; Feasibility Studies; Female; Humans; Male; Middle Aged; Neoplasm Staging; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Remission Induction; Survival Rate; Urinary Bladder Neoplasms

2009
Radiotherapy with concurrent carbogen and nicotinamide in bladder carcinoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Nov-20, Volume: 28, Issue:33

    Topics: Aged; Aged, 80 and over; Carbon Dioxide; Cystectomy; Female; Humans; Male; Middle Aged; Neoplasm Staging; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Urinary Bladder Neoplasms

2010
Acute toxicity profile and compliance to accelerated radiotherapy plus carbogen and nicotinamide for clinical stage T2-4 laryngeal cancer: results of a phase III randomized trial.
    International journal of radiation oncology, biology, physics, 2012, Feb-01, Volume: 82, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Carbon Dioxide; Carcinoma, Squamous Cell; Deglutition Disorders; Female; Humans; Intubation, Gastrointestinal; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Staging; Netherlands; Niacinamide; Oxygen; Patient Compliance; Radiation-Sensitizing Agents; Radiodermatitis; Stomatitis; Vitamin B Complex

2012
Accelerated radiotherapy with carbogen and nicotinamide for laryngeal cancer: results of a phase III randomized trial.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, May-20, Volume: 30, Issue:15

    Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carbon Dioxide; Carcinoma, Squamous Cell; Chi-Square Distribution; Disease-Free Survival; Dose Fractionation, Radiation; Female; Humans; Kaplan-Meier Estimate; Laryngeal Neoplasms; Male; Middle Aged; Netherlands; Niacinamide; Oxygen; Patient Selection; Proportional Hazards Models; Radiation-Sensitizing Agents; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; United Kingdom; Vitamin B Complex

2012
Pattern of CAIX expression is prognostic for outcome and predicts response to ARCON in patients with laryngeal cancer treated in a phase III randomized trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 108, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Carbon Dioxide; Carbonic Anhydrase IX; Carbonic Anhydrases; Female; Humans; Laryngeal Neoplasms; Male; Middle Aged; Niacinamide; Nitroimidazoles; Oxygen; Prognosis; Treatment Outcome

2013
Necrosis predicts benefit from hypoxia-modifying therapy in patients with high risk bladder cancer enrolled in a phase III randomised trial.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2013, Volume: 108, Issue:1

    Topics: Aged; Aged, 80 and over; Carbon Dioxide; Carbonic Anhydrase IV; Cell Hypoxia; Female; Glucose Transporter Type 1; Humans; Male; Middle Aged; Necrosis; Niacinamide; Oxygen; Risk; Urinary Bladder Neoplasms

2013
A 26-gene hypoxia signature predicts benefit from hypoxia-modifying therapy in laryngeal cancer but not bladder cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2013, Sep-01, Volume: 19, Issue:17

    Topics: Carbon Dioxide; Cell Hypoxia; Female; Gene Expression Regulation, Neoplastic; Humans; Laryngeal Neoplasms; Male; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Urinary Bladder Neoplasms

2013
Prognostic value of the proliferation marker Ki-67 in laryngeal carcinoma: results of the accelerated radiotherapy with carbogen breathing and nicotinamide phase III randomized trial.
    Head & neck, 2015, Volume: 37, Issue:2

    Topics: Administration, Inhalation; Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Carbon Dioxide; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Oxygen; Prognosis; Radiation-Sensitizing Agents; Vitamin B Complex

2015
Improved recurrence-free survival with ARCON for anemic patients with laryngeal cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Mar-01, Volume: 20, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Anemia; Biomarkers; Carbon Dioxide; Female; Hemoglobins; Humans; Hypoxia; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Staging; Niacinamide; Oxygen; Prognosis; Radiation-Sensitizing Agents; Radiotherapy; Treatment Outcome

2014
Quality-of-life after radiotherapy for advanced laryngeal cancer: Results of a phase III trial of the Dutch Head and Neck Society.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2016, Volume: 119, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Female; Follow-Up Studies; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Middle Aged; Netherlands; Niacinamide; Oxygen; Quality of Life; Radiation-Sensitizing Agents; Societies, Medical; Surveys and Questionnaires

2016
Long-Term Outcomes of Radical Radiation Therapy with Hypoxia Modification with Biomarker Discovery for Stratification: 10-Year Update of the BCON (Bladder Carbogen Nicotinamide) Phase 3 Randomized Trial (ISRCTN45938399).
    International journal of radiation oncology, biology, physics, 2021, 08-01, Volume: 110, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Carbon Dioxide; Confidence Intervals; Disease-Free Survival; Female; Follow-Up Studies; Humans; Male; Middle Aged; Necrosis; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Regression Analysis; Survival Rate; Time Factors; Treatment Outcome; Tumor Hypoxia; Urinary Bladder Neoplasms

2021
A miRNA signature predicts benefit from addition of hypoxia-modifying therapy to radiation treatment in invasive bladder cancer.
    British journal of cancer, 2021, Volume: 125, Issue:1

    Topics: Biomarkers, Tumor; Carbon Dioxide; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemoradiotherapy; Gene Expression Regulation, Neoplastic; Humans; MicroRNAs; Niacinamide; Oligonucleotide Array Sequence Analysis; Oxygen; Prognosis; Survival Analysis; Urinary Bladder Neoplasms

2021

Other Studies

78 other study(ies) available for carbogen and niacinamide

ArticleYear
Carbogen and nicotinamide: expectations too high? (response to J. Martin Brown)
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1992, Volume: 24, Issue:2

    Topics: Animals; Carbon Dioxide; Humans; Mice; Neoplasms; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents

1992
Extrapolations from laboratory and preclinical studies for the use of carbogen and nicotinamide in radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1992, Volume: 24, Issue:2

    Topics: Animals; Carbon Dioxide; Humans; Mice; Neoplasms; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents

1992
Carbogen and nicotinamide: expectations too high?
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1992, Volume: 24, Issue:2

    Topics: Animals; Carbon Dioxide; Humans; Mice; Neoplasms; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents

1992
Nicotinamide, Fluosol DA and Carbogen: a strategy to reoxygenate acutely and chronically hypoxic cells in vivo.
    British journal of cancer, 1991, Volume: 63, Issue:1

    Topics: Animals; Carbon Dioxide; Carcinoma, Small Cell; Cell Hypoxia; Cell Survival; Dose-Response Relationship, Radiation; Drug Combinations; Drug Therapy, Combination; Female; Fluorocarbons; Hydroxyethyl Starch Derivatives; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Sarcoma, Experimental

1991
Short communication: the addition of carbogen and nicotinamide to a palliative fractionation schedule for locally advanced breast cancer.
    The British journal of radiology, 1995, Volume: 68, Issue:806

    Topics: Aged; Aged, 80 and over; Breast Neoplasms; Carbon Dioxide; Female; Humans; Middle Aged; Niacinamide; Oxygen; Palliative Care; Pilot Projects; Radiation-Sensitizing Agents; Radiotherapy

1995
Conventional radiotherapy combined with carbogen breathing and nicotinamide for malignant gliomas.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1995, Volume: 35, Issue:2

    Topics: Administration, Inhalation; Aged; Brain Neoplasms; Carbon Dioxide; Combined Modality Therapy; Female; Glioma; Humans; Male; Middle Aged; Niacinamide; Oxygen; Radiation Injuries; Radiation-Sensitizing Agents

1995
The combination of nicotinamide and carbogen breathing to improve tumour oxygenation prior to radiation treatment.
    Advances in experimental medicine and biology, 1994, Volume: 361

    Topics: Animals; Carbon Dioxide; Combined Modality Therapy; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Niacinamide; Oxygen; Oxygen Consumption; Radiation Tolerance; Radiation-Sensitizing Agents; Respiration

1994
Carbogen breathing with nicotinamide improves the oxygen status of tumours in patients.
    British journal of cancer, 1995, Volume: 72, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Female; Humans; Male; Middle Aged; Neoplasms; Niacinamide; Oxygen; Partial Pressure; Radiation-Sensitizing Agents

1995
The effects of carbogen and nicotinamide on intravascular oxyhaemoglobin saturations in SCCVII and KHT murine tumours.
    British journal of cancer, 1995, Volume: 71, Issue:5

    Topics: Animals; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Hypoxia; Female; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Niacinamide; Oxygen; Oxyhemoglobins; Partial Pressure; Radiation Tolerance; Radiation-Sensitizing Agents; Sarcoma, Experimental; Tumor Cells, Cultured

1995
Tumour oxygenation, radiosensitivity, and necrosis before and/or after nicotinamide, carbogen and perflubron emulsion administration.
    International journal of radiation biology, 1995, Volume: 67, Issue:5

    Topics: Animals; Carbon Dioxide; Cell Survival; Fluorocarbons; Humans; Hydrocarbons, Brominated; Hypoxia; Mice; Necrosis; Niacinamide; Oxygen; Tumor Cells, Cultured

1995
Are direct measures of tumor oxygenation reflective of changes in tumor radiosensitivity following oxygen manipulation?
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:3

    Topics: Animals; Carbon Dioxide; Cell Survival; Female; Mice; Mice, Inbred C3H; Niacinamide; Oxygen; Oxyhemoglobins; Radiation-Sensitizing Agents; Radiotherapy Dosage; Sarcoma, Experimental

1995
Reoxygenation in a C3H mouse mammary carcinoma. The importance of chronic rather than acute hypoxia.
    Acta oncologica (Stockholm, Sweden), 1995, Volume: 34, Issue:3

    Topics: Animals; Carbon Dioxide; Cell Hypoxia; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred Strains; Niacinamide; Oxygen; Oxygen Consumption; Radiation-Sensitizing Agents; Radiotherapy Dosage; Time Factors

1995
Perfusion changes in the RIF-1 tumour and normal tissues after carbogen and nicotinamide, individually and combined.
    British journal of cancer, 1995, Volume: 71, Issue:6

    Topics: Administration, Inhalation; Animals; Body Temperature; Carbon Dioxide; Cell Hypoxia; Drug Interactions; Female; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Niacinamide; Oxygen; Perfusion; Radiation-Sensitizing Agents; Regional Blood Flow; Rubidium

1995
ARCON.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 1994, Volume: 6, Issue:5

    Topics: Animals; Carbon Dioxide; Humans; Neoplasms; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy Dosage

1994
Nicotinamide and carbogen: relationship between pO2 and radiosensitivity in three tumour lines.
    International journal of radiation biology, 1994, Volume: 65, Issue:3

    Topics: Animals; Carbon Dioxide; Cell Survival; Humans; Mice; Niacinamide; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured

1994
[The effect of nicotinamide and carbogen on the radiation tolerance of the spinal cord of the rat].
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1994, Volume: 170, Issue:11

    Topics: Animals; Carbon Dioxide; Niacinamide; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Rats; Spinal Cord

1994
Reducing acute and chronic hypoxia in tumours by combining nicotinamide with carbogen breathing.
    Acta oncologica (Stockholm, Sweden), 1994, Volume: 33, Issue:4

    Topics: Animals; Carbon Dioxide; Cell Hypoxia; Female; Mammary Neoplasms, Experimental; Mice; Niacinamide; Oxygen; Partial Pressure; Radiation-Sensitizing Agents

1994
Acute effects of accelerated radiotherapy in combination with carbogen breathing and nicotinamide (ARCON).
    Acta oncologica (Stockholm, Sweden), 1994, Volume: 33, Issue:4

    Topics: Administration, Inhalation; Aged; Carbon Dioxide; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Humans; Male; Middle Aged; Niacinamide; Oxygen; Pilot Projects; Radiation-Sensitizing Agents

1994
The radiation response of KHT sarcomas following nicotinamide treatment and carbogen breathing.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1994, Volume: 31, Issue:2

    Topics: Administration, Inhalation; Animals; Carbon Dioxide; Cell Hypoxia; Cell Survival; Combined Modality Therapy; Dose-Response Relationship, Radiation; Drug Therapy, Combination; Female; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Niacinamide; Oxygen; Radiation Dosage; Radiation-Sensitizing Agents; Sarcoma, Experimental; Tumor Cells, Cultured

1994
Influence of combined use of nicotinamide and carbogen on rat spinal cord radiation tolerance.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1994, Volume: 31, Issue:2

    Topics: Administration, Inhalation; Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Therapy, Combination; Male; Niacinamide; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Rats; Rats, Inbred Strains; Spinal Cord

1994
Middle dose rate irradiation in combination with carbogen inhalation selectively and more markedly increases the responses of SCCVII tumors.
    International journal of radiation oncology, biology, physics, 1994, Apr-30, Volume: 29, Issue:1

    Topics: Animals; Bone Marrow; Carbon Dioxide; Cell Survival; DNA Damage; Intestines; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Radiotherapy Dosage

1994
The detection and modification of the hypoxic fraction in quiescent cell populations in murine solid tumours.
    The British journal of radiology, 1993, Volume: 66, Issue:790

    Topics: Animals; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Survival; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Niacinamide; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Sarcoma; Tumor Cells, Cultured

1993
Radiosensitization of SCCVII tumours and normal tissues by nicotinamide and carbogen: analysis by micronucleus assay.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1993, Volume: 28, Issue:2

    Topics: Animals; Carbon Dioxide; Carcinoma, Squamous Cell; Dose-Response Relationship, Drug; Drug Therapy, Combination; Male; Mice; Mice, Inbred C3H; Micronucleus Tests; Niacinamide; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents

1993
Nicotinamide and carbogen: major effect on the radiosensitivity of EMT6 and HRT18 tumours.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1993, Volume: 28, Issue:3

    Topics: Animals; Carbon Dioxide; Cell Survival; Female; Humans; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation Dosage; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured

1993
Pharmacokinetics of varying doses of nicotinamide and tumour radiosensitisation with carbogen and nicotinamide: clinical considerations.
    British journal of cancer, 1993, Volume: 68, Issue:6

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Cell Hypoxia; Cell Survival; Dose-Response Relationship, Drug; Least-Squares Analysis; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Niacinamide; Oxygen; Radiation-Sensitizing Agents

1993
Should carbogen and nicotinamide be given throughout the full course of fractionated radiotherapy regimens?
    International journal of radiation oncology, biology, physics, 1993, Dec-01, Volume: 27, Issue:5

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy Dosage; X-Rays

1993
Comparison of the enhancement of tumor responses to fractionated irradiation by SR 4233 (tirapazamine) and by nicotinamide with carbogen.
    International journal of radiation oncology, biology, physics, 1994, Jan-01, Volume: 28, Issue:1

    Topics: Animals; Antineoplastic Agents; Carbon Dioxide; Combined Modality Therapy; Drug Combinations; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Tirapazamine; Triazines

1994
Further evaluation of nicotinamide and carbogen as a strategy to reoxygenate hypoxic cells in vivo: importance of nicotinamide dose and pre-irradiation breathing time.
    British journal of cancer, 1993, Volume: 68, Issue:2

    Topics: Administration, Inhalation; Animals; Carbon Dioxide; Cell Hypoxia; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Injections, Intraperitoneal; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents

1993
Carbogen and nicotinamide as radiosensitizers in a murine mammary carcinoma using conventional and accelerated radiotherapy.
    International journal of radiation oncology, biology, physics, 1996, Jan-15, Volume: 34, Issue:2

    Topics: Animals; Body Weight; Carbon Dioxide; Dose-Response Relationship, Radiation; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Niacinamide; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Radiotherapy Dosage

1996
Comparison of two techniques for detecting tumour hypoxia: a fluorescent immunochemical method and an in vitro colony assay.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1996, Volume: 39, Issue:2

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Cell Hypoxia; Cell Survival; Cesium Radioisotopes; DNA Damage; DNA, Neoplasm; Drug Combinations; Emulsions; Female; Fluorescent Antibody Technique, Indirect; Fluorocarbons; Humans; Hydrocarbons, Brominated; Mammary Neoplasms, Animal; Mice; Mice, Nude; Niacinamide; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Rectal Neoplasms; Theophylline; Tumor Cells, Cultured; Tumor Stem Cell Assay

1996
Radiosensitisation in normal tissues with oxygen, carbogen or nicotinamide: therapeutic gain comparisons for fractionated x-ray schedules.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1996, Volume: 39, Issue:1

    Topics: Animals; Carbon Dioxide; Chromium Radioisotopes; Dose-Response Relationship, Radiation; Drug Combinations; Edetic Acid; Female; Hematocrit; Intestinal Mucosa; Kidney; Lung; Metabolic Clearance Rate; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Niacinamide; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Radiotherapy Dosage; Respiration; Skin; X-Ray Therapy

1996
Radiotherapy with carbogen breathing and nicotinamide in head and neck cancer: feasibility and toxicity.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1995, Volume: 37, Issue:3

    Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma, Mucoepidermoid; Carcinoma, Squamous Cell; Feasibility Studies; Female; Humans; Hypopharyngeal Neoplasms; Laryngeal Neoplasms; Male; Middle Aged; Mouth Neoplasms; Neoplasm Staging; Niacinamide; Oropharyngeal Neoplasms; Oxygen; Palliative Care; Radiation Injuries; Radiation-Sensitizing Agents; Radiotherapy Dosage

1995
An attempt to enhance chemosensitivity of quiescent cell populations in solid tumors by combined treatment with nicotinamide and carbogen.
    Journal of cancer research and clinical oncology, 1996, Volume: 122, Issue:9

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Division; Cell Hypoxia; Cisplatin; Drug Screening Assays, Antitumor; Drug Synergism; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Micronuclei, Chromosome-Defective; Niacinamide; Oxygen; Sarcoma, Experimental

1996
Transient perfusion and radiosensitizing effect after nicotinamide, carbogen, and perflubron emulsion administration.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1996, Volume: 39, Issue:3

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Emulsions; Female; Fluorocarbons; Humans; Hydrocarbons, Brominated; Melanoma; Mice; Mice, Nude; Microscopy, Fluorescence; Neoplasm Transplantation; Niacinamide; Oxygen; Perfusion; Radiation-Sensitizing Agents; Rectal Neoplasms; Regional Blood Flow; Sensitivity and Specificity; Tumor Cells, Cultured

1996
The potential for improving radiotherapy outcome by improving the oxygen supply to solid tumours.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1996, Volume: 172 Suppl 2

    Topics: Animals; Carbon Dioxide; Cell Hypoxia; Cells, Cultured; Humans; Mice; Neoplasms; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Radiotherapy Dosage

1996
ARCON.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1996, Volume: 172 Suppl 2

    Topics: Animals; Carbon Dioxide; Cell Hypoxia; Humans; Mice; Neoplasms; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Time Factors

1996
Efficacy of agents counteracting hypoxia in fractionated radiation regimes.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1996, Volume: 41, Issue:2

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Cell Hypoxia; Emulsions; Female; Fluorocarbons; Humans; Hydrocarbons, Brominated; Mammary Neoplasms, Experimental; Mice; Niacinamide; Oxygen; Radiation Tolerance; Radiation-Sensitizing Agents; Radiotherapy; Radiotherapy Dosage; Rectal Neoplasms; Tirapazamine; Triazines; Tumor Cells, Cultured

1996
Carbogen and nicotinamide combined with unconventional radiotherapy in glioblastoma multiforme: a new modality treatment.
    International journal of radiation oncology, biology, physics, 1997, Feb-01, Volume: 37, Issue:3

    Topics: Administration, Inhalation; Adult; Aged; Carbon Dioxide; Combined Modality Therapy; Female; Glioblastoma; Humans; Male; Middle Aged; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Radiotherapy Dosage; Supratentorial Neoplasms; Survival Rate

1997
Tolerance to nicotinamide and carbogen with radiation therapy for glioblastoma.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1997, Volume: 43, Issue:1

    Topics: Carbon Dioxide; Glioblastoma; Humans; Niacinamide; Oxygen; Radiation-Sensitizing Agents

1997
Hyperbaric oxygen improves tumor radiation response significantly more than carbogen/nicotinamide.
    Radiation research, 1997, Volume: 147, Issue:6

    Topics: Animals; Carbon Dioxide; Female; Hyperbaric Oxygenation; Neoplasms, Experimental; Niacinamide; Oxygen; Rats; Rats, Inbred F344

1997
Accelerated radiotherapy with carbogen and nicotinamide (ARCON) in high grade malignant gliomas.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1997, Volume: 43, Issue:3

    Topics: Brain Neoplasms; Carbon Dioxide; Combined Modality Therapy; Glioma; Humans; Niacinamide; Oxygen; Radiation-Sensitizing Agents

1997
Early skin response to fractionated doses of pions for determining therapeutic gain factors.
    The Tokai journal of experimental and clinical medicine, 1996, Volume: 21, Issue:2

    Topics: Animals; Carbon Dioxide; Cell Hypoxia; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Mesons; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Relative Biological Effectiveness; Skin

1996
Is hyperbaric oxygen more effective than carbogen/nicotinamide in tumor radiation response?
    Radiation research, 1997, Volume: 148, Issue:5

    Topics: Animals; Carbon Dioxide; Hyperbaric Oxygenation; Hypoxia; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Rats

1997
Comments on hyperbaric oxygen and carbogen/nicotinamide with fractionated radiation.
    Radiation research, 1997, Volume: 148, Issue:5

    Topics: Carbon Dioxide; Humans; Hyperbaric Oxygenation; Hypoxia; Models, Biological; Neoplasms; Niacinamide; Oxygen; Radiotherapy; Radiotherapy Dosage

1997
Combination of fractionated irradiation with nicotinamide and carbogen in R1H-tumours of the rat and its pulmonary metastases.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1997, Volume: 45, Issue:2

    Topics: Animals; Carbon Dioxide; Combined Modality Therapy; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Drug; Female; Lung; Lung Neoplasms; Neoplasm Recurrence, Local; Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Rats; Rhabdomyosarcoma; Skin Neoplasms; Treatment Outcome

1997
Accelerated radiotherapy with carbogen and nicotinamide (ARCON) for laryngeal cancer.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1998, Volume: 48, Issue:2

    Topics: Actuarial Analysis; Administration, Inhalation; Administration, Oral; Adult; Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma; Cell Division; Cell Hypoxia; Dose Fractionation, Radiation; Feasibility Studies; Female; Follow-Up Studies; Humans; Laryngeal Neoplasms; Laryngectomy; Lymphatic Metastasis; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Niacinamide; Oxygen; Prospective Studies; Radiation-Sensitizing Agents; Radiotherapy Dosage; Salvage Therapy; Survival Rate

1998
The effect of combined nicotinamide and carbogen treatments in human tumour xenografts: oxygenation and tumour control studies.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1998, Volume: 48, Issue:2

    Topics: Administration, Inhalation; Animals; Carbon Dioxide; Cell Hypoxia; Drug Combinations; Glioblastoma; Humans; Injections, Intraperitoneal; Mice; Mice, Nude; Neoplasm Transplantation; Neurofibrosarcoma; Niacinamide; Oxygen; Oxygen Consumption; Radiation-Sensitizing Agents; Radiotherapy Dosage; Sarcoma; Sarcoma, Experimental; Skin Neoplasms; Transplantation, Heterologous

1998
Preclinical evaluation of the novel hypoxic marker 99mTc-HL91 (Prognox) in murine and xenograft systems in vivo.
    International journal of radiation oncology, biology, physics, 1998, Nov-01, Volume: 42, Issue:4

    Topics: Adenocarcinoma; Animals; Carbon Dioxide; Carcinoma; Cell Hypoxia; Colonic Neoplasms; Contrast Media; Humans; Lung Neoplasms; Mice; Mice, Inbred CBA; Mice, SCID; Niacinamide; Organotechnetium Compounds; Oximes; Oxygen; Radiopharmaceuticals; Sarcoma

1998
Vascular architecture and microenvironmental parameters in human squamous cell carcinoma xenografts: effects of carbogen and nicotinamide.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 1999, Volume: 50, Issue:2

    Topics: Animals; Benzimidazoles; Blood Vessels; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Division; Endothelium, Vascular; Humans; Hypoxia; Laryngeal Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Niacinamide; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents; Theophylline; Transplantation, Heterologous; Tumor Cells, Cultured

1999
Comparison of the effectiveness of tirapazamine and carbogen with nicotinamide in enhancing the response of a human tumor xenograft to fractionated irradiation.
    Radiation oncology investigations, 1999, Volume: 7, Issue:3

    Topics: Animals; Carbon Dioxide; Carcinoma, Squamous Cell; Cell Survival; Chemotherapy, Adjuvant; Combined Modality Therapy; Disease Models, Animal; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Female; Humans; Male; Mice; Mice, SCID; Neoplasm Transplantation; Niacinamide; Oxygen; Oxygen Consumption; Pharyngeal Neoplasms; Radiation Dosage; Radiation-Sensitizing Agents; Sensitivity and Specificity; Tirapazamine; Triazines; Tumor Cells, Cultured

1999
Clinical outcome and tumour microenvironmental effects of accelerated radiotherapy with carbogen and nicotinamide.
    Acta oncologica (Stockholm, Sweden), 1999, Volume: 38, Issue:7

    Topics: Carbon Dioxide; Cell Division; Cell Hypoxia; Head and Neck Neoplasms; Humans; Niacinamide; Oxygen; Radiation-Sensitizing Agents

1999
Enhancement of tumor perfusion and oxygenation by carbogen and nicotinamide during single- and multifraction irradiation.
    Radiation research, 2000, Volume: 153, Issue:1

    Topics: Animals; Carbocyanines; Carbon Dioxide; Cell Hypoxia; Combined Modality Therapy; Dose Fractionation, Radiation; Etanidazole; Female; Fibrosarcoma; Fluorescent Dyes; Hydrocarbons, Fluorinated; Indicators and Reagents; Mice; Mice, Inbred C3H; Niacinamide; Oxygen; Oxygen Consumption; Radiation-Sensitizing Agents; Tumor Cells, Cultured

2000
Hypoxic radiosensitizers in radical radiotherapy for patients with bladder carcinoma: hyperbaric oxygen, misonidazole, and accelerated radiotherapy, carbogen and nicotinamide.
    The Journal of urology, 2000, Volume: 163, Issue:5

    Topics: Carbon Dioxide; Humans; Hyperbaric Oxygenation; Misonidazole; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Urinary Bladder Neoplasms

2000
Effects of nicotinamide and carbogen on tumour oxygenation, blood flow, energetics and blood glucose levels.
    British journal of cancer, 2000, Volume: 82, Issue:12

    Topics: Animals; Blood Glucose; Carbon Dioxide; Energy Metabolism; Female; Hydralazine; Magnetic Resonance Imaging; Niacinamide; Oxygen; Prolactinoma; Rats; Rats, Inbred WF; Time Factors

2000
Effects of nicotinamide and carbogen on oxygenation in human tumor xenografts measured with luminescense based fiber-optic probes.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2000, Volume: 57, Issue:1

    Topics: Analysis of Variance; Animals; Carbon Dioxide; Cell Hypoxia; Disease Models, Animal; Fiber Optic Technology; Humans; Linear Models; Luminescent Measurements; Niacinamide; Nitroimidazoles; Optical Fibers; Oxygen; Radiation-Sensitizing Agents; Sensitivity and Specificity; Transplantation, Heterologous; Tumor Cells, Cultured

2000
Fractionated irradiation combined with carbogen breathing and nicotinamide of two human glioblastomas grafted in nude mice.
    Radiation research, 2001, Volume: 155, Issue:1 Pt 1

    Topics: Administration, Inhalation; Animals; Brain Neoplasms; Carbon Dioxide; Cell Division; Combined Modality Therapy; Dose Fractionation, Radiation; Drug Therapy, Combination; Female; Glioblastoma; Humans; Mice; Mice, Nude; Niacinamide; Oxygen; Radiation Injuries, Experimental; Radiation-Sensitizing Agents; Skin; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2001
Effects of the interaction between carbogen and nicotinamide on R3230 Ac tumor blood flow in Fischer 344 rats.
    Radiation research, 2001, Volume: 155, Issue:5

    Topics: Animals; Arterioles; Blood Pressure; Carbon Dioxide; Female; Heart Rate; Mammary Neoplasms, Experimental; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Regional Blood Flow

2001
Photodynamic therapy for malignant mesothelioma: preclinical studies for optimization of treatment protocols.
    Photochemistry and photobiology, 2001, Volume: 73, Issue:4

    Topics: Animals; Carbon Dioxide; Combined Modality Therapy; Disease Models, Animal; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Humans; Mesoporphyrins; Mesothelioma; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Niacinamide; Oxygen; Photochemotherapy; Photosensitizing Agents

2001
The modification of human tumour blood flow using pentoxifylline, nicotinamide and carbogen.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2002, Volume: 62, Issue:1

    Topics: Administration, Inhalation; Administration, Oral; Adult; Aged; Carbon Dioxide; Female; Humans; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Neoplasms; Niacinamide; Oxygen; Pentoxifylline; Radiation-Sensitizing Agents; Regional Blood Flow; Time Factors; Up-Regulation

2002
Pharmacology and toxicity of nicotinamide combined with domperidone during fractionated radiotherapy.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2002, Volume: 63, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Carbon Dioxide; Carcinoma; Domperidone; Dose Fractionation, Radiation; Female; Humans; Male; Middle Aged; Nausea; Niacinamide; Oropharyngeal Neoplasms; Oxygen; Radiation-Sensitizing Agents; Vomiting

2002
The effect of nicotinamide & hyperoxic gases on blood glucose.
    Advances in experimental medicine and biology, 2003, Volume: 510

    Topics: Animals; Blood Glucose; Blood Pressure; Carbon Dioxide; Female; Hyperoxia; Niacinamide; Oxygen; Rats; Rats, Inbred F344

2003
Preclinical studies on how to deal with patient intolerance to nicotinamide and carbogen.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2004, Volume: 70, Issue:3

    Topics: Animals; Carbon Dioxide; Dose Fractionation, Radiation; Dose-Response Relationship, Radiation; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasm Transplantation; Niacinamide; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Radiotherapy Dosage

2004
Radiotoxicity on bone marrow after 89Sr therapy radiosensitized by nicotinamide and carbogen in mice.
    Nuclear medicine communications, 2004, Volume: 25, Issue:7

    Topics: Administration, Inhalation; Animals; Bone Marrow; Carbon Dioxide; Chromosomes; Female; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Mice, Inbred BALB C; Micronucleus Tests; Niacinamide; Oxygen; Radiation Injuries; Radiation Tolerance; Radiation-Sensitizing Agents; Radiopharmaceuticals; Strontium Radioisotopes

2004
Effects of nicotinamide and carbogen in different murine colon carcinomas: immunohistochemical analysis of vascular architecture and microenvironmental parameters.
    International journal of radiation oncology, biology, physics, 2004, Sep-01, Volume: 60, Issue:1

    Topics: Animals; Benzimidazoles; Bromodeoxyuridine; Carbon Dioxide; Cell Hypoxia; Cell Line, Tumor; Colonic Neoplasms; Female; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Niacinamide; Nitroimidazoles; Oxygen; Radiation-Sensitizing Agents

2004
Is sensitization with nicotinamide and carbogen dependent on nicotinamide concentration at the time of irradiation?
    International journal of radiation biology, 2004, Volume: 80, Issue:7

    Topics: Animals; Carbon Dioxide; Dose-Response Relationship, Drug; Female; Mammary Neoplasms, Experimental; Mice; Mice, Inbred CBA; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Skin

2004
Physiological noise in murine solid tumours using T2*-weighted gradient-echo imaging: a marker of tumour acute hypoxia?
    Physics in medicine and biology, 2004, Aug-07, Volume: 49, Issue:15

    Topics: Animals; Biomarkers, Tumor; Carbon Dioxide; Cell Hypoxia; Cell Line, Tumor; Computer Simulation; Fibrosarcoma; Flunarizine; Image Interpretation, Computer-Assisted; Magnetic Resonance Imaging; Male; Mice; Mice, Inbred C3H; Models, Biological; Niacinamide; Oxygen; Reproducibility of Results; Sensitivity and Specificity; Signal Processing, Computer-Assisted; Stochastic Processes

2004
In vivo determination of tumor oxygenation during growth and in response to carbogen breathing using 15C5-loaded alginate capsules as fluorine-19 magnetic resonance imaging oxygen sensors.
    International journal of radiation oncology, biology, physics, 2004, Nov-01, Volume: 60, Issue:3

    Topics: Alginates; Animals; Carbon Dioxide; Cell Hypoxia; Crown Ethers; Fluorine; Glucuronic Acid; Hexuronic Acids; Hydralazine; Magnetic Resonance Imaging; Neoplasms; Niacinamide; Oxygen; Partial Pressure; Radiation-Sensitizing Agents; Rats; Rats, Inbred WF; Vasodilator Agents

2004
Hyperthermic enhancement of tumor radiosensitization strategies.
    Immunological investigations, 2005, Volume: 34, Issue:3

    Topics: Administration, Inhalation; Animals; Carbon Dioxide; Cell Death; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; Endothelium, Vascular; Female; Hyperthermia, Induced; Male; Mice; Mice, Inbred C3H; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344

2005
Modulation of hypoxia in murine liver metastases of colon carcinoma by nicotinamide and carbogen.
    Radiation research, 2005, Volume: 164, Issue:3

    Topics: Animals; Carbon Dioxide; Carcinoma; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Combinations; Female; Liver Neoplasms; Mice; Mice, Inbred BALB C; Niacinamide; Oxygen

2005
The prognostic value of endogenous hypoxia-related markers for head and neck squamous cell carcinomas treated with ARCON.
    Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2006, Volume: 79, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm; Biomarkers, Tumor; Carbon Dioxide; Carbonic Anhydrase IX; Carbonic Anhydrases; Carcinoma, Squamous Cell; Clinical Trials, Phase II as Topic; Combined Modality Therapy; Disease-Free Survival; Female; Glucose Transporter Type 1; Glucose Transporter Type 3; Head and Neck Neoplasms; Humans; Hypoxia; Immunohistochemistry; Male; Middle Aged; Niacinamide; Oxygen; Predictive Value of Tests; Prognosis; Radiation Dosage; Treatment Outcome

2006
Hypoxia inducible factor-1 alpha and vascular endothelial growth factor expression are associated with a poor prognosis in patients with nasopharyngeal carcinoma receiving radiotherapy with carbogen and nicotinamide.
    Clinical oncology (Royal College of Radiologists (Great Britain)), 2008, Volume: 20, Issue:8

    Topics: Adult; Aged; Biomarkers; Carbon Dioxide; Female; Gene Expression; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Nasopharyngeal Neoplasms; Niacinamide; Oxygen; Prognosis; Radiation-Sensitizing Agents; Survival Analysis; Vascular Endothelial Growth Factor A

2008
Blood flow and Vd (water): both biomarkers required for interpreting the effects of vascular targeting agents on tumor and normal tissue.
    Molecular cancer therapeutics, 2009, Volume: 8, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Biomarkers, Tumor; Carbon Dioxide; Female; Humans; Male; Middle Aged; Neoplasms; Niacinamide; Organ Specificity; Oxygen; Regional Blood Flow; Water

2009
Elusive goal of targeting tumor hypoxia for therapeutic gain.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, May-20, Volume: 30, Issue:15

    Topics: Carbon Dioxide; Carcinoma, Squamous Cell; Female; Humans; Laryngeal Neoplasms; Male; Niacinamide; Oxygen; Radiation-Sensitizing Agents; Vitamin B Complex

2012
Computed tomography-based tumour volume as a predictor of outcome in laryngeal cancer: results of the phase 3 ARCON trial.
    European journal of cancer (Oxford, England : 1990), 2014, Volume: 50, Issue:6

    Topics: Carbon Dioxide; Clinical Trials, Phase III as Topic; Combined Modality Therapy; Disease-Free Survival; Female; Follow-Up Studies; Humans; Laryngeal Neoplasms; Male; Middle Aged; Neoplasm Staging; Niacinamide; Outcome Assessment, Health Care; Oxygen; Prognosis; Radiation-Sensitizing Agents; Randomized Controlled Trials as Topic; Tomography, X-Ray Computed; Tumor Burden

2014
The effect of carbogen breathing and nicotinamide added to standard (chemo)radiation treatment of advanced cervical cancer in Indonesia.
    International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 2014, Volume: 24, Issue:9

    Topics: Administration, Oral; Adult; Aged; Antineoplastic Agents; Carbon Dioxide; Chemoradiotherapy; Cisplatin; Female; Follow-Up Studies; Humans; Indonesia; Middle Aged; Neoplasm Staging; Niacinamide; Oxygen; Prognosis; Prospective Studies; Radiation-Sensitizing Agents; Respiratory Therapy; Survival Rate; Uterine Cervical Neoplasms; Vitamin B Complex

2014
Targeting tumour hypoxia to improve outcome of stereotactic radiotherapy.
    Acta oncologica (Stockholm, Sweden), 2015, Volume: 54, Issue:9

    Topics: Administration, Inhalation; Animals; Carbon Dioxide; Cell Hypoxia; Diphosphates; Female; Hyperthermia, Induced; Mammary Neoplasms, Experimental; Mice, Inbred C3H; Niacinamide; Nimorazole; Oxygen; Radiation-Sensitizing Agents; Radiosurgery; Radiotherapy Dosage; Stilbenes; Vitamin B Complex

2015
A Gene Signature for Selecting Benefit from Hypoxia Modification of Radiotherapy for High-Risk Bladder Cancer Patients.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2017, Aug-15, Volume: 23, Issue:16

    Topics: Aged; Carbon Dioxide; Clinical Trials, Phase III as Topic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Kaplan-Meier Estimate; Male; Middle Aged; Niacinamide; Oxygen; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Urinary Bladder Neoplasms

2017
Concurrent carbogen and nicotinamide with radiation therapy in muscle invasive bladder cancer: A report on feasibility in the Australian setting.
    Journal of medical imaging and radiation oncology, 2021, Volume: 65, Issue:6

    Topics: Aged; Australia; Carbon Dioxide; Feasibility Studies; Humans; Muscles; Neoplasm Recurrence, Local; Niacinamide; Oxygen; Urinary Bladder Neoplasms

2021