carbocyanines and phorbol-12-myristate

carbocyanines has been researched along with phorbol-12-myristate* in 1 studies

Other Studies

1 other study(ies) available for carbocyanines and phorbol-12-myristate

ArticleYear
Cyanine fluorophores for cellular protection against ROS in stimulated macrophages and two-photon ROS detection.
    Organic & biomolecular chemistry, 2015, Jul-14, Volume: 13, Issue:26

    We report the first example of a novel two-photon active, biocompatible, and macrophage cell-membrane permeable carbazole-based cyanine fluorophore for the detection of three biologically important ROS, namely, ˙OH, O2(-) and OCl(-) in solution. This versatile probe shows cellular protection not only in stimulated macrophages from phorbol-12-myristate-13-acetate-induced morphological changes but also lipopolysaccharide-induced cytotoxicity by quenching with the O2(-) and OCl(-) production, respectively. Such protection could be visualized by a distinct change in the fluorescence intensity of the probe.

    Topics: Animals; Carbazoles; Carbocyanines; Cytoprotection; Fluorescent Dyes; HeLa Cells; Humans; Lipopolysaccharides; Macrophages; Mice; Oxidative Stress; Phorbol Esters; Photons; RAW 264.7 Cells; Reactive Oxygen Species

2015