carbidopa has been researched along with methyldopa in 59 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 35 (59.32) | 18.7374 |
| 1990's | 7 (11.86) | 18.2507 |
| 2000's | 5 (8.47) | 29.6817 |
| 2010's | 12 (20.34) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Borison, RL; Giardina, WJ; Mosnaim, AD; Pedemonte, WA; Sabelli, HC; Vazquez, AJ | 1 |
| Dollery, CT; Kersting, F; Reid, JL | 2 |
| Frankel, RJ; Ganong, WF; Reid, IA | 1 |
| Feuerstein, C; Gavend, M; Pellat, J; Perret, J; Serre, F; Tanche, M | 2 |
| Marsden, CD; Mindham, RH; Parkes, JD | 1 |
| Gaul, SL; Sweet, CS | 1 |
| Goodale, DB; Moore, KE | 1 |
| Ludden, CT; Scriabine, A; Stone, CA; Watkins, CJ; Wurtman, RJ | 1 |
| Horie, R; Yamori, Y | 1 |
| McDowell, FH; Sweet, RD | 1 |
| Calne, DB; Fermaglich, J | 1 |
| Collin, C; Eckernäs, SA; Grahnén, A; Ling-Andersson, A; Nilsson, M; Tiger, G | 1 |
| Männistö, PT; Tuomainen, P; Tuominen, RK | 1 |
| Medenica, M; Nikolić, K | 1 |
| Davoudi, H; Durso, R; Feldman, RG; Szabo, G | 1 |
| Issopoulos, PB | 2 |
| Conway, EL; Jarrott, B; Louis, WJ | 1 |
| Bazan, E; de Yebenes, JG; Mena, MA; Muradas, V; Reiriz, J | 1 |
| Endo, Y | 1 |
| Chase, TN; Fermaglich, J | 1 |
| Atkins, FL; Beaven, MA; Keiser, HR | 1 |
| Clark, CM; Lotti, VJ; Stone, CA; Torchiana, ML | 1 |
| Antonaccio, MJ; Burrell, R; Robson, RD | 1 |
| Mones, RJ | 1 |
| Paparo, AA; Tate, SS | 1 |
| Andén, NE; Henning, M | 1 |
| Duvoisin, RC; Marsden, CD | 1 |
| Fahn, S; Prasad, AL | 1 |
| Fahn, S | 1 |
| Dean, RC; Murphy, JA; Paparo, AA | 1 |
| Da Prada, M; Haefely, WE; Keller, HH; Kettler, R; Pieri, L | 1 |
| Fersel, J; Melman, A; Weinstein, P | 1 |
| Gelber, LR; Neumeyer, JL | 1 |
| Kemi, M; Kondo, M; Maki, E; Tanabe, K | 1 |
| Bräutigam, K; Morgenstern, R; Sohr, R | 1 |
| Deleu, D; Ebinger, G; Michotte, Y; Sarre, S | 1 |
| Andre, MH; Bruguerolle, B; Grignon, S | 1 |
| Balogh-Nemes, K; Horvai, G; Klebovich, I; Tolokán, A | 1 |
| Dolezalová, M; Fanali, S | 1 |
| Forsberg, M; Gogos, JA; Huotari, M; Hyttinen, J; Karayiorgou, M; Koponen, O; Männistö, PT; Raasmaja, A | 1 |
| Fekete, MI; Fülöp, F; Homicskó, KG; Kertész, I; Nagy, GM; Radnai, B; Tóth, BE; Tóth, G | 1 |
| Chamsaz, M; Fadaee, J; Safavi, A | 1 |
| Fu, HY; Li, SF; Li, YN; Nie, JF; Wu, HL; Yu, RQ; Yu, YJ | 1 |
| Fisher, R; Jackson, MJ; Jenner, P; Rose, S; Tayarani-Binazir, KA; Zoubiane, G | 1 |
| Barba, E; Bugamelli, F; Marcheselli, C; Raggi, MA | 1 |
| Bengel, G; Ebersbach, G; Ehret, R; Jugel, C; Klostermann, F; Muhlack, S; Müller, T | 1 |
| Bonfim, RR; Byrro, RM; César, IC; Gomes, SA; Mundim, IM; Pianetti, GA; Santana E Silva Cardoso, FF; Souza Teixeira, L | 1 |
| Muhlack, S; Müller, T | 1 |
3 review(s) available for carbidopa and methyldopa
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Biochemical plasticity of synaptic transmission: a critical review of Dale's Principle.
Topics: 5-Hydroxytryptophan; Animals; Brain; Carbidopa; Deamination; Dihydroxyphenylalanine; Evoked Potentials; Humans; Mental Disorders; Methyldopa; Neural Inhibition; Neurons; Neurotransmitter Agents; Phenethylamines; Probenecid; Rabbits; Rats; Receptors, Drug; Synapses; Synaptic Transmission; Visual Perception | 1976 |
The pharmacology of Parkinson's disease: basic aspects and recent advances.
Topics: Animals; Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Brain; Bromocriptine; Carbidopa; Corpus Striatum; Dopamine; Ergolines; Humans; Kidney; Kinetics; Levodopa; Lisuride; Liver; Methyldopa; Norepinephrine; Parkinson Disease; Pergolide; Receptors, Dopamine; Selegiline; Serotonin; Stereotyped Behavior; Substantia Nigra; Tyramine | 1984 |
6 trial(s) available for carbidopa and methyldopa
| Article | Year |
|---|---|
Clinical and cardiovascular effects of alpha methyldopa in combination with decarboxylase inhibitors.
Topics: Adult; Benserazide; Blood Pressure; Carbidopa; Carboxy-Lyases; Clinical Trials as Topic; Cold Temperature; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Hypnotics and Sedatives; Male; Methyldopa; Middle Aged; Salivation; Valsalva Maneuver | 1977 |
Psychiatric symptoms during l-dopa therapy for Parkinson's disease and their relationship to physical disability.
Topics: Aged; Amantadine; Carbidopa; Clinical Trials as Topic; Depression; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Interview, Psychological; Levodopa; Male; Mental Status Schedule; Methyldopa; Middle Aged; Parkinson Disease; Placebos; Recurrence; Trihexyphenidyl | 1976 |
Comparative multiple-dose pharmacokinetics of controlled-release levodopa products.
Topics: Adult; Antiparkinson Agents; Carbidopa; Delayed-Action Preparations; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Humans; Levodopa; Male; Metabolic Clearance Rate; Methyldopa; Neurologic Examination; Parkinson Disease | 1992 |
Methyldopa or methyldopahydrazine as levodopa synergists.
Topics: Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Methyldopa; Parkinson Disease | 1973 |
Evaluation of alpha methyl dopa and alpha methyl dopa hydrazine with L-dopa therapy.
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Methyldopa; Middle Aged; Parkinson Disease | 1974 |
Elevation of total homocysteine levels in patients with Parkinson's disease treated with duodenal levodopa/carbidopa gel.
Topics: Aged; Antiparkinson Agents; Carbidopa; Drug Combinations; Duodenum; Female; Gels; Homocysteine; Humans; Hyperhomocysteinemia; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 2011 |
50 other study(ies) available for carbidopa and methyldopa
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Site of action of methyldopa in lowering the blood pressure in man.
Topics: Benserazide; Binding Sites; Blood Pressure; Carbidopa; Depression, Chemical; Humans; Methyldopa | 1978 |
Role of central and peripheral mechanisms in the action of alpha-methyldopa on blood pressure and renin secretion.
Topics: Animals; Blood Pressure; Carbidopa; Depression, Chemical; Dogs; Drug Interactions; Female; Infusions, Parenteral; Injections, Intraventricular; Male; Methyldopa; Nordefrin; Renin; Time Factors | 1977 |
Plasma O-methyldopa in levodopa-induced dyskinesias. A bioclinical investigation.
Topics: Aged; Benserazide; Carbidopa; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 1977 |
Does O-methyl-dopa play a role in levodopa-induced dyskinesias?
Topics: Adult; Aged; Benserazide; Carbidopa; Dyskinesia, Drug-Induced; Female; Humans; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 1977 |
Antagonism of conditioned salivation in conscious dogs by antihypertensive drugs.
Topics: Animals; Antihypertensive Agents; Atropine; Carbidopa; Clonidine; Conditioning, Classical; Dogs; Drug Interactions; Female; Male; Methyldopa; Pilocarpine; Salivation | 1977 |
A comparison of the effects of decarboxylase inhibitors on L-dopa-induced circling behavior and the conversion of dopa to dopamine in the brain.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benserazide; Brain; Brocresine; Carbidopa; Dopamine; Hydrazines; Levodopa; Male; Methyldopa; Rats; Time Factors | 1976 |
Enhancement of the anti-hypertensive effect of methyldopa and other anti-hypertensive drugs by carbidopa in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Carbidopa; Catecholamines; Dose-Response Relationship, Drug; Drug Synergism; Hydrazines; Hypertension; Male; Methyldopa; Myocardium; Rats | 1976 |
Experimental studies on the pathogenesis and prophylaxis of stroke in stroke-prone spontaneously hypertensive rats (SHR). (2) Prophylactic effect of moderate control of blood pressure on stroke.
Topics: Animals; Carbidopa; Carboxy-Lyases; Cerebrovascular Disorders; Heart Rate; Hydralazine; Hypertension; Levodopa; Male; Methyldopa; Rats | 1975 |
Five years' treatment of Parkinson's disease with levodopa. Therapeutic results and survival of 100 patients.
Topics: Adult; Aged; Carbidopa; Female; Follow-Up Studies; Humans; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 1975 |
Gout induced by L-dopa and decarboxylase inhibitors.
Topics: Aged; Carbidopa; Carboxy-Lyases; Gout; Humans; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 1976 |
Different in vivo properties of three new inhibitors of catechol O-methyltransferase in the rat.
Topics: Amidines; Animals; Benzophenones; Biogenic Monoamines; Brain; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Homovanillic Acid; Hypothalamus; Levodopa; Male; Methyldopa; Nitriles; Nitrophenols; Pyridones; Rats; Rats, Inbred Strains; Tolcapone | 1992 |
Coulometric determination of levodopa, methyldopa and carbidopa.
Topics: Azo Compounds; Carbidopa; Electrochemistry; Levodopa; Methyldopa | 1990 |
Magnitude of response to levodopa in Parkinson disease as it relates to peripheral and central measurements of levodopa and associated metabolites.
Topics: Aged; Carbidopa; Drug Combinations; Homovanillic Acid; Humans; Levodopa; Male; Methyldopa; Middle Aged; Parkinson Disease | 1989 |
Sensitive colorimetric assay of carbidopa and methyldopa using tetrazolium blue chloride in pharmaceutical products.
Topics: Capsules; Carbidopa; Colorimetry; Indicators and Reagents; Methyldopa; Nitroblue Tetrazolium; Tablets; Temperature | 1989 |
Spectrophotometric determination of microquantities of Carbidopa, Levodopa and alpha-methyldopa using molybdatophosphoric acid.
Topics: Carbidopa; Levodopa; Methyldopa; Molybdenum; Phosphoric Acids; Spectrophotometry, Ultraviolet | 1989 |
Sites of actions of alpha 2 agonists in the brain and periphery.
Topics: Adrenergic alpha-Agonists; Animals; Binding Sites; Blood Pressure; Brain; Carbidopa; Clonidine; Decarboxylation; Methyldopa; Neurotransmitter Agents; Radioligand Assay; Receptors, Adrenergic, alpha; Vasoconstriction | 1988 |
Pharmacokinetics of L-dopa in patients with Parkinson's disease.
Topics: Biotransformation; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disability Evaluation; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Kinetics; Levodopa; Methyldopa; Parkinson Disease; Receptors, Dopamine; Receptors, Dopamine D2; Tiapamil Hydrochloride | 1987 |
Suppression and potentiation of 5-hydroxytryptophan-induced hypoglycaemia by alpha-monofluoromethyldopa: correlation with the accumulation of 5-hydroxytryptamine in the liver.
Topics: 5-Hydroxytryptophan; Animals; Blood Glucose; Brain; Carbidopa; Carboxy-Lyases; Kidney; Lipopolysaccharides; Liver; Male; Methyldopa; Mice; Serotonin | 1987 |
Dopa decarboxylase in medullary carcinoma of the thyroid.
Topics: Adrenal Gland Neoplasms; Amine Oxidase (Copper-Containing); Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Carcinoma; Cresols; Dihydroxyphenylalanine; Dopa Decarboxylase; Histamine; Histidine; Humans; Hydrazines; Hydroxylamines; Methyldopa; Methylhistidines; Norepinephrine; Pheochromocytoma; Serotonin; Thyroid Gland; Thyroid Neoplasms; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase | 1973 |
Comparison of centrally mediated hypotensive action of methyldopa and DOPA in cats.
Topics: Adrenergic alpha-Antagonists; Amino Acids; Animals; Antihypertensive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benzoates; Blood Pressure; Carbidopa; Cats; Cerebral Ventricles; Dihydroxyphenylalanine; Disulfides; Dopamine beta-Hydroxylase; Female; Imidazoles; Male; Methyldopa; Perfusion; Phentolamine; Pyrimidines; Spiro Compounds; Sulfhydryl Compounds; Time Factors | 1973 |
The effects of L-dopa and alpha-methyldopa on reflexes and sympathetic nerve function.
Topics: Animals; Atropine; Barbiturates; Benserazide; Blood Pressure; Carbidopa; Carotid Arteries; Dogs; Electric Stimulation; Heart Rate; Hindlimb; Levodopa; Methyldopa; Monoamine Oxidase Inhibitors; Neurons; Perfusion; Posture; Reflex; Regional Blood Flow; Sympathetic Nervous System; Vagotomy; Vagus Nerve | 1974 |
Dopa decarboxylase from visceral ganglion and gill of two lamellibranch mollusca as it relates to ciliary activity.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Carbon Radioisotopes; Carboxy-Lyases; Cilia; Dopa Decarboxylase; Electric Stimulation; Ganglia; Gills; In Vitro Techniques; Methyldopa; Mollusca; Serotonin; Time Factors; Tritium | 1973 |
Urinary excretion of noradrenaline after treatment with alpha-methyldopa: inhibition by a central nervous mechanism.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Depression, Chemical; Epinephrine; Hydrazines; Injections, Intraperitoneal; Male; Methyldopa; Norepinephrine; Rats; Tritium | 1974 |
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Methyldopa; Mice; Movement Disorders; Parkinson Disease; Phenoxybenzamine; Pimozide; Reserpine | 1974 |
3-O-methyl metabolites of catecholamines: automated fluorometric assay and their plasma levels in patients receiving levodopa and carbidopa.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Autoanalysis; Blood-Brain Barrier; Brain Chemistry; Carbidopa; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Homovanillic Acid; Humans; Methods; Methyldopa; Microchemistry; Phenylacetates; Spectrometry, Fluorescence; Time Factors | 1974 |
"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine.
Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Injections, Intramuscular; Male; Methyldopa; Middle Aged; Movement Disorders; Parkinson Disease; Pyridoxine | 1974 |
DOPA decarboxylase activity in the nervous system and the ctenidium of the freshwater clam, Musculium (Sphaerium) transversum.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Bivalvia; Carbidopa; Dopa Decarboxylase; Methyldopa; Nervous System; Respiratory System | 1984 |
Further studies on the effect of chronic alpha-methyldopa administration upon the central nervous system and sexual function in male rats.
Topics: Animals; Carbidopa; Central Nervous System; Erectile Dysfunction; Humans; Libido; Male; Methyldopa; Norepinephrine; Penis; Rats; Reflex; Sexual Behavior, Animal; Substance Withdrawal Syndrome; Yohimbine | 1984 |
"On-off" phenomenon in Parkinson's disease.
Topics: Animals; Carbidopa; Humans; Levodopa; Methyldopa; Parkinson Disease | 1984 |
Determination of the enantiomeric purity of levodopa, methyldopa, carbidopa and tryptophan by use of chiral mobile phase high-performance liquid chromatography.
Topics: Capsules; Carbidopa; Chromatography, High Pressure Liquid; Copper; Copper Sulfate; Drug Contamination; Levodopa; Methyldopa; Phenylalanine; Stereoisomerism; Tablets; Tryptophan | 1983 |
Influence of carbidopa, an aromatic amino acid decarboxylase inhibitor, on the development of autoimmune hemolytic anemia in NZB mice.
Topics: Anemia, Hemolytic, Autoimmune; Animals; Body Weight; Carbidopa; Coombs Test; Female; Hematocrit; Levodopa; Male; Methyldopa; Mice; Mice, Inbred NZB | 1983 |
3-O-methyl-DOPA is not involved in the development of behavioral supersensitivity after repeated L-dopa administration in 6-OHDA lesioned rats.
Topics: Animals; Apomorphine; Carbidopa; Catechol O-Methyltransferase Inhibitors; Corpus Striatum; Levodopa; Male; Methyldopa; Motor Activity; Oxidopamine; Rats; Rats, Wistar; Receptors, Dopamine; Stereotyped Behavior; Substantia Nigra | 1994 |
Simultaneous monitoring of levodopa, dopamine and their metabolites in skeletal muscle and subcutaneous tissue in different pharmacological conditions using microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbidopa; Chromatography, High Pressure Liquid; Dialysis; Dogs; Dopamine; Electrochemistry; Extracellular Space; Injections, Intravenous; Levodopa; Male; Methyldopa; Muscles; Skin | 1993 |
Circadian phase dependent pharmacokinetics of L-dopa, its main metabolites (3-OMD, HVA, DOPAC) and carbidopa in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Area Under Curve; Carbidopa; Circadian Rhythm; Half-Life; Homovanillic Acid; Levodopa; Male; Methyldopa; Rats; Rats, Wistar | 1996 |
Automated determination of levodopa and carbidopa in plasma by high-performance liquid chromatography-electrochemical detection using an on-line flow injection analysis sample pretreatment unit.
Topics: Animals; Antiparkinson Agents; Automation; Carbidopa; Chromatography, High Pressure Liquid; Dogs; Electrochemistry; Flow Injection Analysis; Levodopa; Male; Methyldopa; Reference Standards | 1997 |
Enantiomeric separation of dihydroxyphenylalanine (DOPA), methyldihydroxyphenylalanine (MDOPA) and hydrazinomethyldihydroxyphenylalanine (CDOPA) by using capillary electrophoresis with sulfobutyl ether-beta-cyclodextrin as a chiral selector.
Topics: beta-Cyclodextrins; Carbidopa; Cyclodextrins; Dihydroxyphenylalanine; Electrophoresis, Capillary; Indicators and Reagents; Methyldopa; Stereoisomerism | 2000 |
Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Anesthesia; Animals; Carbidopa; Catechol O-Methyltransferase; Corpus Striatum; Dopamine; Dopamine Agents; Female; Homovanillic Acid; Levodopa; Male; Methoxyhydroxyphenylglycol; Methyldopa; Mice; Mice, Inbred C57BL; Mice, Knockout; Microdialysis; Norepinephrine | 2002 |
Binding site of salsolinol: its properties in different regions of the brain and the pituitary gland of the rat.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Binding Sites; Binding, Competitive; Brain; Carbidopa; Clonidine; Corpus Striatum; Dopamine; Dopamine Agonists; Dopamine Antagonists; Enzyme Inhibitors; Female; Isoquinolines; Kinetics; Lactation; Levodopa; Male; Mazindol; Median Eminence; Methyldopa; Pituitary Gland; Pituitary Gland, Posterior; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, Dopamine; Reserpine | 2003 |
Simultaneous kinetic-spectrophotometric determination of carbidopa, levodopa and methyldopa in the presence of citrate with the aid of multivariate calibration and artificial neural networks.
Topics: Calibration; Carbidopa; Citric Acid; Humans; Hydrogen-Ion Concentration; Kinetics; Levodopa; Methyldopa; Neural Networks, Computer; Spectrophotometry | 2007 |
Quantitative analysis of levodopa, carbidopa and methyldopa in human plasma samples using HPLC-DAD combined with second-order calibration based on alternating trilinear decomposition algorithm.
Topics: Algorithms; Calibration; Carbidopa; Chemistry Techniques, Analytical; Chromatography; Chromatography, High Pressure Liquid; Humans; Levodopa; Methyldopa; Models, Chemical; Reproducibility of Results; Solvents | 2010 |
The timing of administration, dose dependence and efficacy of dopa decarboxylase inhibitors on the reversal of motor disability produced by L-DOPA in the MPTP-treated common marmoset.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Callithrix; Carbidopa; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Synergism; Enzyme Inhibitors; Female; Levodopa; Male; Methyldopa; Motor Activity; Movement Disorders | 2010 |
Determination of L-dopa, carbidopa, 3-O-methyldopa and entacapone in human plasma by HPLC-ED.
Topics: Antiparkinson Agents; Calibration; Carbidopa; Catechols; Chromatography, High Pressure Liquid; Drug Combinations; Humans; Levodopa; Methyldopa; Nitriles; Reproducibility of Results; Solid Phase Extraction | 2011 |
Development and validation of a high-performance liquid chromatography-electrospray ionization-MS/MS method for the simultaneous quantitation of levodopa and carbidopa in human plasma.
Topics: Administration, Oral; Carbidopa; Chromatography, High Pressure Liquid; Drug Stability; Female; Humans; Levodopa; Male; Methyldopa; Reproducibility of Results; Sensitivity and Specificity; Tablets; Tandem Mass Spectrometry | 2011 |
Levodopa-related cysteinyl-glycine and cysteine reduction with and without catechol-O-methyltransferase inhibition in Parkinson's disease patients.
Topics: Aged; Analysis of Variance; Antiparkinson Agents; Carbidopa; Catechol O-Methyltransferase; Catechols; Chromatography, Reverse-Phase; Cysteine; Dipeptides; Drug Delivery Systems; Female; Humans; Levodopa; Male; Methyldopa; Middle Aged; Nitriles; Parkinson Disease; Time Factors | 2014 |