carbidopa has been researched along with hydrazine in 157 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 149 (94.90) | 18.7374 |
1990's | 4 (2.55) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 4 (2.55) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
Ekins, S; Williams, AJ; Xu, JJ | 1 |
Walker, E | 1 |
Chadwick, D; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH | 1 |
Leibowitz, M; Lieberman, A | 1 |
Calne, DB; Gielen, AC; Gillespie, MM; Kartzinel, R; Perlow, M; Sadowsky, DA; TEYCHENNE, P | 1 |
Lipper, S | 1 |
Coxon, A; Greenacre, JK; Petrie, A; Reid, JL | 1 |
Cronin, BL; Ludden, CT; Porter, CC; Scriabine, A; Stone, CA; Sweet, CS; Ulm, EH; Watkins, CJ; Wurtman, RJ | 1 |
de Fine Olivarius, B; Dupont, E; Magnussen, I; Prange-Hansen, A | 1 |
de Fine Olivarius, B; Dupont, E; Engbaek, F; Magnussen, I | 1 |
Anders, TF; Barchas, JD; Berger, PA; Cann, HM; Ciaranello, RD | 1 |
Ogawa, M; Tohgi, H | 1 |
Savery, F | 2 |
Battistin, L; Meneghetti, G; Rigotti, S; Saia, A | 1 |
Diamond, SG; Markham, CH; Treciokas, LJ | 1 |
Ohlin, H; Stenberg, P; Wadstein, J | 1 |
Cotzias, GC; Miller, ST; Papavasiliou, PS; Rosal, VL | 1 |
Dorner, A; Wajsbort, E; Wajsbort, J | 1 |
Hokkanen, E; Myllylä, VV; Saarinen, A; Tokola, O | 1 |
Brambilla, F; Guastalla, A; Maffei, C; Nobile, P; Ponzano, M; Rovere, C; Scarone, S | 1 |
Del Pesce, M; Di Bella, P; Forastieri, L; Paggi, A; Quattrini, A | 1 |
Bowers, MB; Howieson, J; Rosenbaum, D; Van Woert, MH | 1 |
Lee, LA; Leebaw, WJ; Woolf, PD | 1 |
Chadwick, D; Hallett, M; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH | 1 |
Gillin, JC; Magyar, RL; Wyatt, RJ | 1 |
Barbieri, S; Bevilacqua, M; Lanfredini, M; Micossi, P; Nitti, F; Norbiato, G; Raggi, U | 1 |
Green, J; Haycook, W; Kilgore, M; Stephens, R | 1 |
Birkmayer, W; Mentasti, M; Podiwinsky, F; Riederer, P | 1 |
Barone, DA; Martin, HL | 1 |
Adamkov, J; Drobný, M; Fundárek, J; Svaleková, A | 1 |
Bernstein, RM | 1 |
Bender, DA; Earl, CJ; Lees, AJ | 1 |
Brown, GM; Garfinkel, PE; Godse, DD; Stancer, HC; Vranic, M; Warsh, JJ | 1 |
Estey, E; Goldstein, M; Gopinathan, G; Lieberman, A; Ohashi, T; Sauter, A | 1 |
Jotkowitz, S | 1 |
Hershman, JM; Wingert, TD | 1 |
Mölsä, P; Rinne, UK | 1 |
Frohman, LA; Kovathana, N; Nakawatase, C; Szabo, M | 1 |
Brotchi, J; Dresse, A; Gerebtzoff, MA; Lepot, M; Scuvee-Moreau, J | 1 |
Grimm, W; Schönberger, W; Ziegler, R | 1 |
Coscia, CJ; Mitchell, J | 1 |
Jenner, PG; Jones, MK; Ramsay, ID | 1 |
Airoldi, L; Watkins, CJ; Wiggins, JF; Wurtman, RJ | 1 |
Klawans, HL; Kramer, J; Nausieda, PA; Wiener, WJ | 1 |
Messiha, FS | 1 |
Barkhatova, VP; Markova, ED | 1 |
Bonnet, K; Friedhoff, AJ; Rosengarten, H | 1 |
Kuzuya, F; Mori, K; Sakamoto, N; Yoshimine, N | 1 |
Hall-Tipping, DL; Joseph, MH | 1 |
Deze, J; Völler, GW | 1 |
Avery, GS; Brogden, RN; Pinder, RM; Sawyer, PR; Speight, TM | 1 |
Hucker, HB; Stuart, EK; Vickers, S | 1 |
Hanzal, F | 2 |
Bronaugh, RL; Garver, DL; Rutledge, CO; Wenger, GR | 1 |
Lee, MC; Lippert, DM; Loewenson, RB; Martin, WE; Resch, JA; Tolosa, ES | 1 |
Aarskog, D; Fevang, FO; Stoa, RF; Thorsen, T | 1 |
Watkins, CJ; Wurtman, RJ | 1 |
Bianchine, JR | 1 |
Anderson, F; Joynt, R; Rivera-Calimlim, L; Tandon, D | 1 |
Hayek, J | 1 |
Borri, P; Borri-Voltattorni, C; Minelli, A | 1 |
Ball, SG; Lee, MR | 1 |
Brodt, B; Grimm, W; Schönberger, W; Ziegler, R | 2 |
Rampton, DS | 1 |
De la Garza, R; Lombardo, L | 1 |
Lin, JT; Ziegler, DK | 1 |
True, AC | 1 |
Brown, GM; Garfinkel, PE; Stancer, HC; Warsh, JJ | 1 |
Goodwin, BL; Johnson, RD; Ruthven, CR; Sandler, M | 1 |
Goodale, DB; Moore, KE | 1 |
Carrera, N; Marti-Masso, JF; Martínez-Lage, JM | 2 |
Mizuno, Y; Obayashi, T; Ueki, A; Yoshida, M | 1 |
Garfinkel, PE; Sibony, D; Stancer, HC; Warsh, JJ | 1 |
Londoõ, R | 1 |
Omoto, T | 1 |
Ludden, CT; Scriabine, A; Stone, CA; Watkins, CJ; Wurtman, RJ | 1 |
Sethy, VH; Van Woert, MH | 2 |
Stancer, HC; Warsh, JJ | 2 |
Engel, J; Katzman, R; Sharpless, N; Thal, L; Wolfson, L | 1 |
Gabreëls, FJ; Joosten, EM; Keyser, A; Korten, JJ | 1 |
Jaatoul, N; Kertesz, A; McInnis, W; Paty, DW | 1 |
Goodgold, A; Jonas, S; Leibowitz, M; Lieberman, A | 1 |
Baker, AB; Lee, MC; Loewenson, RB; Martin, WE; Resch, JA; Tolosa, ES | 1 |
Critchley, E | 1 |
McDowell, FH; Stern, PH; Sweet, RD; Wasterlain, CG | 1 |
Kishikawa, H; Ohmoto, T | 1 |
Corsini, GU; Mangoni, A; Marrosu, F; Spissu, A | 1 |
Cerone, G; Nurzia, A; Pirro, R; Vacca, U | 1 |
Celesia, GG; Wanamaker, WM | 1 |
Fellman, JH; Fujita, TS; Heriza, EL; Roth, ES | 1 |
Birket-Smith, E; Dupont, E; Hansen, E; Mikkelsen, B; Pakkenberg, H; Presthus, J; Rautakorpi, I; Riman, E; Rinne, UK | 1 |
Hildick-Smith, M | 1 |
Blandina, P; Grenader, A; Healy, DP; Huo, TL | 1 |
Goshima, Y; Misu, Y; Nakamura, S | 1 |
Berger, HJ; Horstink, MW; Pasman, JW; van't Hof, MA; Zijlmans, JC | 1 |
Rinne, JO; Rinne, UK | 1 |
Goodrich, C; Lechner, R; Slone, W | 1 |
Da Prada, M; Haefely, WE; Kettler, R; Schaffner, R; Zürcher, G | 1 |
Berglund, B; Kaijser, L; Sachs, C | 1 |
Azevedo, M; Coelho, H; Manso, C | 1 |
Kawai, K; Kitamura, J; Mori, H; Sugie, S | 1 |
Yu, HZ | 1 |
Chase, TN; Fermaglich, J | 1 |
Clark, WG; Dewherst, WG; Oldendorf, WH | 1 |
Atkins, FL; Beaven, MA; Keiser, HR | 1 |
Glasgow, GL; Henley, JW; Willoughby, EW | 1 |
Minsker, DH; Stokes, AL | 1 |
Rondot, P | 1 |
Braham, J; Sarova-Pinhas, I | 1 |
Cotzias, GC; Mena, I; Papavasiliou, PS | 1 |
Fermaglich, J | 1 |
Malmnäs, CO | 1 |
Mones, RJ | 2 |
Olanow, CW; Schwartz, AM; Spencer, A | 1 |
Andrews, CJ; Somerville, B | 1 |
Friedman, E; Gershon, S | 1 |
Barry, PE; Marsden, CD; Parkes, JD; Zilkha, KJ | 1 |
Klawans, HL; Ringel, SP | 1 |
Fenard, S; Schmitt, H | 1 |
Dick, P; Eisenring, JJ; Tissot, R; Yanniotis, G | 1 |
Mars, H | 2 |
Andén, NE; Henning, M | 1 |
Calne, DB; Johnson, RD; Reid, JL; Ruthven, CR; Sandler, M | 1 |
Clark, C; Lotti, VJ | 1 |
Diamond, SG; Markham, C; Treciokas, LJ | 1 |
Brody, JA; Chase, TN; Holden, EM | 1 |
Fahn, S | 1 |
Miller, EM; Wiener, L | 1 |
Cotzias, GC; Dahl, LK; Düby, SE | 1 |
Casey, DE; Gerlach, J | 1 |
Magnussen, I; Van Woert, MH | 1 |
Bender, DA | 1 |
Goldstein, M; Gopinathan, G; Hiesiger, E; Lieberman, AN; Nelson, J; Neophytides, A; Walker, R | 1 |
Gerdes, U; Lehmann, K; Ulm, G | 1 |
Kamenetskiĭ, VK | 1 |
Anderson, GM; Chouinard, G; Gauthier, S; Purdy, WC; Young, SN | 1 |
Caraceni, T; Cocchi, D; Giovannini, P; Martinez-Campos, A; Müller, EE; Novelli, A | 1 |
Juorio, AV | 1 |
Agnoli, A; Baldassarre, M; D'Urso, R; De Giorgio, G; Falaschi, P; Rocco, A; Ruggieri, S | 1 |
de Vries, T; Garbis-Berkvens, JM; Peters, PW; Rauws, AG; van Logten, MJ; Vos, JG | 1 |
Giorgi, O; Rubio, MC | 1 |
Pogson, CI; Smith, SA | 1 |
Carolei, A; Masturzo, P; Murialdo, G; Polleri, A | 1 |
Gulliver, PA; Hagan, RM; Raxworthy, MJ | 1 |
Ahier, RG; Ashworth, S; Hume, SP; Opacka-Juffry, J | 1 |
Boukherroub, R; Das, MR; Li, M; Szunerits, S; Wang, Q | 1 |
de Vries, EF; Di Gialleonardo, V; Dierckx, RA; Kema, IP; Ramakrishnan, NK; van Waarde, A; Visser, AK; Willemsen, AT | 1 |
1 review(s) available for carbidopa and hydrazine
Article | Year |
---|---|
Levodopa and decarboxylase inhibitors: a review of their clinical pharmacology and use in the treatment of parkinsonism.
Topics: Benserazide; Binding Sites; Carbidopa; Carboxy-Lyases; Drug Interactions; Humans; Hydrazines; Kinetics; Levodopa; Liver Function Tests; Parkinson Disease | 1976 |
31 trial(s) available for carbidopa and hydrazine
Article | Year |
---|---|
Comparison of dopa decarboxylase inhibitor (carbidopa) combined with levodopa and levodopa alone on the cardiovascular system of patients with parkinson's disease.
Topics: Adult; Aged; Arrhythmias, Cardiac; Carbidopa; Cardiac Complexes, Premature; Cardiovascular System; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrazines; Hypotension, Orthostatic; Levodopa; Male; Middle Aged; Parkinson Disease; Tachycardia | 1975 |
Bromocriptine and levodopa (with or without carbidopa) in parkinsonism.
Topics: Aged; Bromocriptine; Carbidopa; Clinical Trials as Topic; Disability Evaluation; Dose-Response Relationship, Drug; Drug Combinations; Drug Evaluation; Ergolines; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Placebos; Time Factors | 1976 |
Comparison of levodopa with carbidopa or benserazide in parkinsonism.
Topics: Aged; Benserazide; Carbidopa; Consumer Behavior; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
[Effect of MK-486 alone on Parkinsonism; studies on the clinical symptoms and catecholamine concentrations in the blood, urine and cerebrospinal fluid].
Topics: Aged; Carbidopa; Catecholamines; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease | 1977 |
Amantadine and a fixed combination of levodopa and carbidopa in the treatment of Parkinson's disease.
Topics: Adult; Aged; Amantadine; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
Long-term treatment of Parkinson's disease with L-Dopa and Dopa-decarboxylase inhibitor: therapeutic results and side effects.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1978 |
A double-blind comparison of levodopa, Madopa, and Sinemet in Parkinson disease.
Topics: Adult; Benserazide; Carbidopa; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Nausea; Parkinson Disease; Vomiting | 1978 |
Effects of apomorphine and apomorphine-L-dopa-carbidopa on alcohol post-intoxication symptoms.
Topics: Adult; Aged; Alcoholic Intoxication; Alcoholism; Apomorphine; Carbidopa; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Male; Middle Aged | 1978 |
Treatment of parkinsonism with N-n-propyl norapomorphine and levodopa (with or without carbidopa).
Topics: Aged; Apomorphine; Carbidopa; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1978 |
A comparative clinical investigation of the therapeutic effect of levodopa alone and in combination with a decarboxylase inhibitor (carbidopa) in cases of Parkinson's disease.
Topics: Aged; Carbidopa; Clinical Trials as Topic; Drug Combinations; Electrocardiography; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors | 1978 |
Effect of a slow release preparation of levodopa on Parkinson's disease in combination with a peripheral decarboxylase inhibitor.
Topics: Adult; Antiparkinson Agents; Carbidopa; Clinical Trials as Topic; Delayed-Action Preparations; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1978 |
Catecholaminergic drugs in chronic schizophrenia.
Topics: Adult; Apomorphine; Carbidopa; Chronic Disease; Clinical Trials as Topic; Drug Therapy, Combination; Follicle Stimulating Hormone; Growth Hormone; Humans; Hydrazines; Imipramine; Levodopa; Luteinizing Hormone; Male; Middle Aged; Placebos; Schizophrenia, Disorganized; Testosterone | 1979 |
[Efficacy and side-effects of long term L-dopa therapy in Parkinsonian syndromes (evaluated by CT scan as well) (author's transl)].
Topics: Adult; Benserazide; Brain; Carbidopa; Clinical Trials as Topic; Confusion; Electrocardiography; Electroencephalography; Female; Humans; Hydrazines; Hyperkinesis; Levodopa; Male; Middle Aged; Parkinson Disease, Secondary; Stomach Diseases; Tomography, X-Ray Computed | 1979 |
[The combined treatment of Parkinson's disease with L-dopa plus decarboxylase inhibitors (carbidopa, benserazide) (author's transl)].
Topics: Aged; Benserazide; Carbidopa; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1979 |
Levodopa with benserazide or carbidopa in Parkinson disease.
Topics: Benserazide; Biological Availability; Carbidopa; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1979 |
[The clinical experience with the decarboxylase-blocked levodopa (Nacom) in the Parkinsonism patients].
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
Amantadine and a fixed combination of carbidopa and levodopa in parkinsonism: a preliminary report.
Topics: Aged; Amantadine; Carbidopa; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
[Treatment of Parkinson's syndrome with L-dopa and L-carbidopa (author's transl)].
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrazines; Hyperkinesis; Levodopa; Male; Middle Aged; Parkinson Disease; Pyridoxine | 1976 |
Madopar versus sinemet. A clinical study on their effectiveness.
Topics: Adult; Aged; Benserazide; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Serine | 1975 |
Alpha methyldopahydrazine as an adjunct to levodopa therapy in Parkinson's disease.
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Placebos; Time Factors | 1975 |
Comparison of dopa decarboxylase inhibitor (carbidopa) combined with levodopa and levodopa alone in Parkinson's disease.
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Mental Disorders; Middle Aged; Movement Disorders; Parkinson Disease | 1975 |
The effects of combining carbidopa with levodopa for Parkinson's disease.
Topics: Carbidopa; Clinical Trials as Topic; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypotension, Orthostatic; Levodopa; Male; Nausea; Parkinson Disease; Vomiting | 1975 |
L-dopa and carbidopa (sinemet) in the management of parkinsonism.
Topics: Aged; Carbidopa; Clinical Trials as Topic; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Prognosis | 1975 |
Treatment of "on-off effect" with a dopa decarboxylase inhibitor.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1975 |
Parkinson's disease treated with Sinemet or Madopar. A controlled multicenter trial.
Topics: Aged; Benserazide; Carbidopa; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
Methyldopa or methyldopahydrazine as levodopa synergists.
Topics: Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Methyldopa; Parkinson Disease | 1973 |
L-alpha-methyldopa hydrazine (Carbidopa) combined with L-dopa in the treatment of Parkinson's disease.
Topics: Aged; Blood Pressure; Carbidopa; Clinical Trials as Topic; Depression, Chemical; Drug Eruptions; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Movement Disorders; Nausea; Parkinson Disease; Placebos; Posture; Vomiting | 1974 |
Evaluation of alpha methyl dopa and alpha methyl dopa hydrazine with L-dopa therapy.
Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Methyldopa; Middle Aged; Parkinson Disease | 1974 |
A double-blind controlled study of MK-486 in Parkinson's disease.
Topics: Aged; Anorexia Nervosa; Antiparkinson Agents; Carbidopa; Clinical Trials as Topic; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Humans; Hydrazines; Male; Middle Aged; Nausea; Parkinson Disease; Placebos | 1973 |
Levodopa combined with MK 486 (L-alpha methyldopahydrazine)--a peripheral decarboxylase inhibitor in Parkinson's disease.
Topics: Adult; Aged; Carbidopa; Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hydrazines; Male; Middle Aged; Movement Disorders; Nausea; Parkinson Disease; Placebos | 1974 |
Sinemet.
Topics: Carbidopa; Clinical Trials as Topic; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease | 1974 |
125 other study(ies) available for carbidopa and hydrazine
Article | Year |
---|---|
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Drug therapy for Parkinsonism.
Topics: Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease | 1976 |
Manipulation of brain serotonin in the treatment of myoclonus.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Aged; Benzodiazepinones; Brain; Carbidopa; Clonazepam; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Hydrazines; Infusions, Parenteral; Male; Middle Aged; Myoclonus; Serotonin | 1975 |
Letter: Psychosis in patient on bromocriptine and levodopa with carbidopa.
Topics: Bromocriptine; Carbidopa; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease; Schizophrenia, Paranoid | 1976 |
Antihypertensive activity of metyrosine in spontaneously hypertensive rats and its enhancement by carbidopa.
Topics: Animals; Blood Pressure; Brain; Carbidopa; Dopamine; Dose-Response Relationship, Drug; Drug Synergism; Hydrazines; Hypertension; Methyltyrosines; Myocardium; Norepinephrine; Rats | 1978 |
Palatal myoclonus treated with 5-hydroxytryptophan and a decarboxylase-inhibitor.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Combinations; Humans; Hydrazines; Male; Muscle Contraction; Myoclonus; Palate | 1977 |
Post-hypoxic intention myoclonus treated with 5-hydroxy-tryptophan and an extracerebral decarboxylase inhibitor.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Hypoxia; Male; Myoclonus | 1978 |
Further observations on the use of 5-hydroxytryptophan in a child with Lesch-Nyhan syndrome.
Topics: 5-Hydroxytryptophan; Carbidopa; Child; Drug Therapy, Combination; Humans; Hydrazines; Lesch-Nyhan Syndrome; Male; Movement Disorders; Self Mutilation; Sleep; Wakefulness | 1978 |
Long-term therapy of myoclonus and other neurologic disorders with L-5-hydroxytryptophan and carbidopa.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Brain; Carbidopa; Drug Therapy, Combination; Epilepsies, Myoclonic; Female; Humans; Hydrazines; Hypoxia, Brain; Long-Term Care; Male; Middle Aged; Myoclonus; Serotonin; Tryptophan | 1977 |
Effects of CNS dopamine augmentation on stimulated prolactin secretion.
Topics: Adult; Carbidopa; Humans; Hydrazines; Insulin; Levodopa; Male; Prolactin; Thyrotropin-Releasing Hormone | 1977 |
Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Benzodiazepinones; Carbidopa; Child, Preschool; Clonazepam; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electroencephalography; Electromyography; Epilepsies, Myoclonic; Epilepsy, Post-Traumatic; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia, Brain; Isocarboxazid; Male; Methysergide; Middle Aged; Myoclonus; Premedication; Tryptophan | 1977 |
Tolerance to the increased locomotor activity produced by L-5-hydroxytryptophan following peripheral decarboxylase inhibition in mice.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Carboxy-Lyases; Drug Tolerance; Hydrazines; Male; Mice; Motor Activity; Time Factors | 1978 |
Effect of metoclopramide, a dopaminergic inhibitor, on renin and aldosterone in idiopathic edema: possible therapeutic approach with levodopa and carbidopa.
Topics: Adult; Aldosterone; Body Weight; Carbidopa; Edema; Female; Humans; Hydrazines; Levodopa; Metoclopramide; Renin; Sodium | 1979 |
Electroencephalographic change in Parkinsonian patients treated with levodopa-carbidopa.
Topics: Aged; Carbidopa; Drug Therapy, Combination; Electroencephalography; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1979 |
Causes of pseudotumor cerebri and papilledema.
Topics: Aged; Carbidopa; Dose-Response Relationship, Drug; Female; Humans; Hydrazines; Levodopa; Papilledema; Parkinson Disease; Pseudotumor Cerebri | 1979 |
[Therapy of rigidity and hypokinesis in old age using Sinemet].
Topics: Aged; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Movement Disorders; Muscle Rigidity; Parkinson Disease, Postencephalitic; Trihexyphenidyl | 1979 |
Reversible haemolytic anaemia after levodopa-carbidopa.
Topics: Aged; Anemia, Hemolytic, Autoimmune; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Male; Parkinson Disease | 1979 |
Niacin depletion in Parkinsonian patients treated with L-dopa, benserazide and carbidopa.
Topics: Adolescent; Adult; Benserazide; Bromocriptine; Carbidopa; Female; Humans; Hydrazines; Levodopa; Male; Micrococcus; Middle Aged; Nicotinamidase; Nicotinic Acids; Parkinson Disease; Tryptophan | 1979 |
The effect of a peripheral decarboxylase inhibitor (carbidopa) on monoamine and neuroendocrine function in man.
Topics: Adult; Carbidopa; Carboxy-Lyases; Female; Glycols; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Prolactin; Tryptamines | 1977 |
Comparative effectiveness of two extracerebral DOPA decarboxylase inhibitors in Parkinson disease.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dihydroxyphenylalanine; Female; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease | 1978 |
Need for uncombined carbidopa to treat parkinsonism.
Topics: Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease | 1978 |
Sinemet and thyroid function in Parkinson disease.
Topics: Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Male; Parkinson Disease; Thyroid Function Tests; Thyroid Gland; Thyrotropin | 1979 |
Effect of the dopa decarboxylase inhibitor MK-486 on L-dopa-induced inhibition of prolactin secretion: evidence for CNS participation in the L-dopa effects.
Topics: Adrenal Medulla; Animals; Brain; Carbidopa; Cerebral Cortex; Depression, Chemical; Hydrazines; Hypothalamus; Levodopa; Male; Pituitary Gland, Anterior; Prolactin; Rats | 1977 |
Action of phenytoin, ethosuximide and of the carbidopa-L-dopa association in semi-chronic cobalt-induced epilepsy in the rat.
Topics: Animals; Carbidopa; Cobalt; Dose-Response Relationship, Drug; Drug Interactions; Electroencephalography; Ethosuximide; Hydrazines; Levodopa; Male; Phenytoin; Rats; Seizures | 1977 |
The effect of nacom (L-dopa and L-carbidopa) on growth hormone secretion in 75 patients with short stature.
Topics: Adolescent; Arginine; Carbidopa; Child; Child, Preschool; Dihydroxyphenylalanine; Dwarfism; Growth Hormone; Humans; Hydrazines; Secretory Rate | 1977 |
Application of paired-ion high-pressure liquid column chromatography to the analysis of L-3,4-dihydroxyphenylalanine metabolites.
Topics: Carbidopa; Chromatography, High Pressure Liquid; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Parkinson Disease | 1978 |
The effect of low dose carbidopa/levodopa on prolactin and growth hormone concentrations in patients with breast cancer and in benign breast tumours.
Topics: Adult; Aged; Breast Neoplasms; Carbidopa; Dihydroxyphenylalanine; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Middle Aged; Prolactin; Thyroxine; Time Factors | 1978 |
Effect of pyridoxine on the depletion of tissue pyridoxal phosphate by carbidopa.
Topics: Animals; Brain; Carbidopa; Dopa Decarboxylase; Dopamine; Hydrazines; Hypothalamus; Levodopa; Liver; Male; Muscles; Pyridoxal Phosphate; Pyridoxine; Rats | 1978 |
Paradoxial response to dopaminergic agents in parkinsonism.
Topics: Acetonitriles; Aged; Carbidopa; Ergolines; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Parkinson Disease; Receptors, Dopamine | 1978 |
Modulation of hepatic aldehyde dehydrogenase by carbidopa.
Topics: Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Carbidopa; Cytoplasm; Hydrazines; Liver; Male; Mitochondria, Liver; Rats | 1978 |
[Pathogenesis and treatment of torsion dystonia].
Topics: Carbidopa; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Epinephrine; Homovanillic Acid; Humans; Hydrazines; Jews; Levodopa; Norepinephrine; Vanilmandelic Acid | 1978 |
Receptor-cell sensitivity modification (RSM) as a model for pathogenesis and treatment of tardive dyskinesia.
Topics: Animals; Carbidopa; Disease Models, Animal; Drug Combinations; Dyskinesia, Drug-Induced; Hydrazines; Levodopa; Rats; Receptors, Dopamine | 1978 |
[Effect of VB6 on L-DOPA decarboxylase activity in the organs of rats given peripheral L-DOPA decarboxylase inhibitors (author's transl)].
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dopa Decarboxylase; Hydrazines; Levodopa; Male; Pyridoxine; Rats | 1978 |
The metabolism of a tryptophan load in rat brain and liver: the influence of L-alpha-methyldopa hydrazine (MK-486, Carbidopa).
Topics: Animals; Brain; Carbidopa; Hydrazines; Kynurenine; Liver; Male; Metabolic Clearance Rate; Rats; Tryptophan; Tryptophan Oxygenase | 1978 |
Further studies on the metabolism of carbidopa, (minus)-L-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid monohydrate, in the human, Rhesus monkey, dog, and rat.
Topics: Animals; Carbidopa; Carbon Radioisotopes; Chromatography, Gas; Chromatography, Thin Layer; Dogs; Female; Haplorhini; Humans; Hydrazines; Isomerism; Macaca mulatta; Male; Mass Spectrometry | 1975 |
Effect of carbidopa on the metabolism of L-dopa in the pigtail monkey.
Topics: Animals; Carbidopa; Dopa Decarboxylase; Female; Haplorhini; Homovanillic Acid; Hydrazines; Lactates; Levodopa; Time Factors | 1976 |
The long-term effects of combining carbidopa with levodopa for Parkinson's disease.
Topics: Carbidopa; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Long-Term Care; Male; Parkinson Disease | 1976 |
The effect of L-dopa with and without decarboxylase inhibitor on growth hormone secretion in children with short stature.
Topics: Administration, Oral; Adolescent; Body Height; Carbidopa; Child; Child, Preschool; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Male; Pituitary Gland; Pituitary Gland, Anterior; Secretory Rate | 1977 |
Suppression of noradrenaline synthesis in sympathetic nerves by carbidopa, an inhibitor of peripheral dopa decarboxylase.
Topics: Adrenergic Fibers; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Dihydroxyphenylalanine; Dopamine; Heart; Hydrazines; Male; Norepinephrine; Peripheral Nerves; Rats; Tyrosine | 1977 |
Drug therapy of Parkinsonism dopaminergic drugs.
Topics: Carbidopa; Humans; Hydrazines; Levodopa; Parkinson Disease | 1977 |
The clinical picture and plasma levodopa metabolite profile of parkinsonian nonresponders. Treatment with levodopa and decarboxylase inhibitor.
Topics: Adult; Carbidopa; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
[Treatment of Parkinson's disease with the combination drug L-carbidopa/L-dopa. Report on a 2 years study].
Topics: Carbidopa; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Movement Disorders; Parkinson Disease; Psychoses, Substance-Induced | 1977 |
Interaction of L-alpha-methyl-alpha-hydrazino-3,4 dihydroxyphenylpropionic acid with dopa-decarboxylase from pig kidney.
Topics: Animals; Carbidopa; Dopa Decarboxylase; Hydrazines; Kidney; Kinetics; Protein Binding; Spectrophotometry; Spectrophotometry, Ultraviolet; Swine | 1977 |
The effect of carbidopa administration on urinary sodium excretion in man. Is dopamine an intrarenal natriuretic hormone?
Topics: Adult; Carbidopa; Creatinine; Dopamine; Female; Humans; Hydrazines; Kidney; Male; Natriuresis; Potassium; Sodium; Time Factors | 1977 |
[Stimulation of the secretion of somatotropin by administration of Nacom (L-dopa and L-carbidopa) in ambulatory patients with retarded growth].
Topics: Adolescent; Ambulatory Care; Carbidopa; Child; Drug Combinations; Growth Disorders; Growth Hormone; Humans; Hydrazines; Levodopa | 1977 |
Hypertensive crisis in a patient given sinemet, metoclopramide, and amitriptyline.
Topics: Acute Disease; Amitriptyline; Carbidopa; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypertension; Levodopa; Metoclopramide; Middle Aged; Parkinson Disease | 1977 |
[Treatment of Parkinson's syndrome with a combination of levodopa and carbidopa].
Topics: Adult; Aged; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1977 |
Psychiatric symptoms with initiation of carbidopa-levodopa treatment.
Topics: Aged; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced | 1976 |
Letter: Carbidopa.
Topics: Carbidopa; Humans; Hydrazines; Parkinson Disease; United States | 1976 |
Effect of carbidopa on prolactin, growth hormone and cortisol secretion in man.
Topics: Adult; Carbidopa; Dopamine; Female; Growth Hormone; Humans; Hydrazines; Hydrocortisone; Male; Middle Aged; Prolactin; Tryptamines | 1976 |
In vivo assessment of decarboxylase inhibition or potentiation: urinary dopamine and L-dopa output after L-dopa administration.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dopamine; Drug Interactions; Humans; Hydrazines; Levodopa; Parkinson Disease; Pyridoxine; Rats | 1976 |
A comparison of the effects of decarboxylase inhibitors on L-dopa-induced circling behavior and the conversion of dopa to dopamine in the brain.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Behavior, Animal; Benserazide; Brain; Brocresine; Carbidopa; Dopamine; Hydrazines; Levodopa; Male; Methyldopa; Rats; Time Factors | 1976 |
[Carbidopa-levodopa, growth hormone and parkinsonism].
Topics: Aged; Carbidopa; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Pituitary Gland; Stimulation, Chemical | 1976 |
[Hormonal effects of carbidopa-levodopa in normal patients].
Topics: Adult; Blood Glucose; Carbidopa; Evaluation Studies as Topic; Female; Growth Hormone; Humans; Hydrazines; Hydrocortisone; Hypothalamus; Insulin; Levodopa; Male; Stimulation, Chemical | 1976 |
[Combined treatment of Parkinsonism with L-dopa and peripheral dopa decarboxylase inhibitors--clinical course of 13 cases and levels of serum/dopa and dopamine].
Topics: Adult; Aged; Benserazide; Carbidopa; Dihydroxyphenylalanine; Dopamine; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
Total and free plasma tryptophan levels in patients with affective disorders: effects of a peripheral decarboxylase inhibitor.
Topics: Adolescent; Adult; Bipolar Disorder; Carbidopa; Depression; Female; Humans; Hydrazines; Male; Middle Aged; Tryptophan | 1976 |
[Treatment of Parkinson's disease with levodopa and a dopa decarboxylase inhibitor].
Topics: Adult; Aged; Carbidopa; Drug Combinations; Drug Evaluation; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Tablets | 1976 |
[Effects and side effects to levodopa in parkinsonism- results of a collaborative study. (5) Combined therapy with a peripheral decarboxylase inhibitor].
Topics: Adult; Aged; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease | 1976 |
Enhancement of the anti-hypertensive effect of methyldopa and other anti-hypertensive drugs by carbidopa in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Carbidopa; Catecholamines; Dose-Response Relationship, Drug; Drug Synergism; Hydrazines; Hypertension; Male; Methyldopa; Myocardium; Rats | 1976 |
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cerebral Palsy; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Methysergide; Middle Aged; Myoclonus; Probenecid; Serotonin | 1975 |
The origin of blood k-hydroxyindoleacetic acid following L-hydrazino-alpha-methyldopa (MK-486).
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carbidopa; Depression, Chemical; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Probenecid; Rats; Serotonin | 1975 |
The origin of blood 5-hydroxyindoleacetic acid following L-hydrazine-alpha-methyldopa (MK-486).
Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Brain Chemistry; Carbidopa; Depression, Chemical; Hydrazines; Hydroxyindoleacetic Acid; Kidney; Liver; Male; Probenecid; Rats; Serotonin | 1975 |
Clinical and metabolic observations on the treatment of myoclonus with L-5-HTP and carbidopa.
Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Homovanillic Acid; Humans; Hydrazines; Hydroxyindoleacetic Acid; Myoclonus; Serotonin | 1976 |
L-dopa therapy combined with peripheral decarboxylase inhibitor (MK-486) in Parkinsonism.
Topics: Adult; Aged; Animals; Carbidopa; Carboxy-Lyases; Cats; Dopamine; Drug Therapy, Combination; Female; Humans; Hydrazines; Injections, Intraperitoneal; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease | 1975 |
[Treatment of Parkinson's syndromes by a combination of levodopa with decarboxylase inhibitors].
Topics: Adult; Aged; Carbidopa; Carboxy-Lyases; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1975 |
Treatment of Sydenham's chorea with a combination of L-dopa and a peripheral dopa decarboxylase inhibitor.
Topics: Acute Disease; Adolescent; Carbidopa; Chorea; Drug Therapy, Combination; Homovanillic Acid; Humans; Hydrazines; Levodopa; Male; Recurrence | 1975 |
[Effect of carbidopa and L-dopa combination on the secretion of growth hormone in normal subjects and in patients with Parkinsonism].
Topics: Carbidopa; Growth Hormone; Humans; Hydrazines; Levodopa; Parkinson Disease; Pituitary Gland; Stimulation, Chemical | 1975 |
L-dopa-carbidopa: combined therapy for the treatment of Parkinson's disease.
Topics: Adult; Aged; Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1976 |
Altered pattern of dopa metabolism.
Topics: Animals; Carbidopa; Cytosol; Dihydroxyphenylalanine; Hydrazines; Kidney; Kinetics; Liver; Mitochondria; Rats; Transaminases | 1976 |
Letter: Alternatives to levodopa.
Topics: Aged; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease | 1976 |
[HGH secretion after oral application of L-dopa and L-carbidopa (author's transl)].
Topics: Administration, Oral; Adolescent; Carbidopa; Child; Growth Hormone; Humans; Hydrazines; Levodopa; Time Factors | 1976 |
Prostaglandin E2 production in rat IMCD cells. II. Possible role for locally formed dopamine.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Carbidopa; Cells, Cultured; Dinoprostone; Dopamine; Dopamine Antagonists; Dose-Response Relationship, Drug; Hydrazines; Kidney Medulla; Kidney Tubules, Collecting; Levodopa; Rats; Tyrosine 3-Monooxygenase | 1991 |
L-dihydroxyphenylalanine methyl ester is a potent competitive antagonist of the L-dihydroxyphenylalanine-induced facilitation of the evoked release of endogenous norepinephrine from rat hypothalamic slices.
Topics: Animals; Binding, Competitive; Carbidopa; Cocaine; Hydrazines; Hypothalamus; In Vitro Techniques; Levodopa; Norepinephrine; Propranolol; Rats; Structure-Activity Relationship; Sulpiride | 1991 |
Severity of Parkinson's disease is a risk factor for peak-dose dyskinesia.
Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Carboxy-Lyases; Dose-Response Relationship, Drug; Drug Combinations; Dyskinesia, Drug-Induced; Humans; Hydrazines; Levodopa; Middle Aged; Motor Skills; Neurologic Examination; Parkinson Disease | 1990 |
Treatment of early Parkinson's disease with controlled-release levodopa preparations.
Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Delayed-Action Preparations; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Parkinson Disease | 1989 |
Central versus peripheral effects on temperature preference and body temperature following alteration of 5-HT in maturing mice.
Topics: 5-Hydroxytryptophan; Aging; Amidines; Animals; Behavior, Animal; Body Temperature; Body Temperature Regulation; Carbidopa; Carboxy-Lyases; Central Nervous System; Double-Blind Method; Drug Interactions; Hydrazines; Injections, Intraperitoneal; Mice; Peripheral Nerves; Piperidines; Serotonin Antagonists | 1989 |
Inhibition of decarboxylase and levels of dopa and 3-O-methyldopa: a comparative study of benserazide versus carbidopa in rodents and of Madopar standard versus Madopar HBS in volunteers.
Topics: Administration, Oral; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Brain; Carbidopa; Delayed-Action Preparations; Dihydroxyphenylalanine; Dogs; Dopa Decarboxylase; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrazines; Kidney; Levodopa; Liver; Male; Mice; Rats; Time Factors; Tyrosine | 1987 |
Autonomic cardiovascular responses in parkinsonism: effect of levodopa with dopa-decarboxylase inhibition.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Autonomic Nervous System; Benserazide; Blood Pressure; Carbidopa; Drug Therapy, Combination; Female; Heart; Heart Rate; Humans; Hydrazines; Levodopa; Male; Middle Aged; Muscle Contraction; Parkinson Disease | 1985 |
Inhibitory effect of drugs used in the treatment of Parkinson's disease on plasma monoamine oxidase activity.
Topics: Adult; Aged; Benserazide; Benzylamine Oxidase; Carbidopa; Female; Humans; Hydrazines; Isoenzymes; Male; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Parkinson Disease | 1985 |
Genetic toxicity of several antihypertensive drugs possessing a hydrazine group.
Topics: Animals; Antihypertensive Agents; Benserazide; Carbidopa; Hydralazine; Hydrazines; Male; Mutagens; Rats; Rats, Inbred ACI | 1985 |
[Clinical significance of cramps of the lower extremities in patients with parkinsonism].
Topics: Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Leg; Levodopa; Male; Middle Aged; Muscle Cramp; Parkinson Disease | 1985 |
Letter: Treatment of post-anoxic intention myoclonus.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Drug Evaluation; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydrazines; Hypoxia; Male; Methysergide; Middle Aged; Myoclonus | 1974 |
Blood-brain barrier to carbidopa (MK-486) and Ro 4-4602, peripheral dopa decarboxylase inhibitors.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood-Brain Barrier; Carbidopa; Carbon Isotopes; Chromatography, Paper; Hydrazines; Oils; Permeability; Tritium; Water | 1973 |
Dopa decarboxylase in medullary carcinoma of the thyroid.
Topics: Adrenal Gland Neoplasms; Amine Oxidase (Copper-Containing); Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Carcinoma; Cresols; Dihydroxyphenylalanine; Dopa Decarboxylase; Histamine; Histidine; Humans; Hydrazines; Hydroxylamines; Methyldopa; Methylhistidines; Norepinephrine; Pheochromocytoma; Serotonin; Thyroid Gland; Thyroid Neoplasms; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase | 1973 |
Aterial blood pressure in dogs: effects of m-tyrosine alone or in combination with inhibitors of aromatic amino acid decarboxylase; relative hypotensive potencies of L-dopa, DL-m-tyrosine, and L-m-tyrosine.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Carbidopa; Dihydroxyphenylalanine; Dogs; Female; Heart Rate; Hydrazines; Male; Tyrosine | 1974 |
[Decarboxylase inhibitors combined with L-dopa in the treatment of Parkinson's disease].
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Benzyl Compounds; Carbidopa; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Parkinson Disease; Phenols | 1974 |
[Treatment of parkinsonism by L-dopa and dopa-decarboxylase inhibitor in a single tablet].
Topics: Antiparkinson Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Parkinson Disease | 1974 |
Short- and long-term approaches to the "on-off" phenomenon.
Topics: Apomorphine; Carbidopa; Dietary Proteins; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Movement Disorders; Parkinson Disease; Time Factors | 1974 |
Treatment of Parkinson's disease with carbidopa, a peripheral decarboxylase inhibitor, and levodopa.
Topics: Aged; Carbidopa; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease | 1974 |
Monoamine precursors and copulatory behavior in the male rat.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Carbidopa; Carboxy-Lyases; Castration; Copulation; Depression, Chemical; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Ejaculation; Female; Hydrazines; Injections, Intraperitoneal; Male; Monoamine Oxidase Inhibitors; Motor Activity; Nialamide; Pargyline; Rats; Sexual Behavior, Animal; Stimulation, Chemical; Testosterone; Time Factors | 1973 |
L-DOPA: centrally mediated emission of seminal fluid in male rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Atropine; Benserazide; Carbidopa; Cyproheptadine; Dihydroxyphenylalanine; Dopamine; Ejaculation; Haloperidol; Hydrazines; Hypophysectomy; Lysergic Acid Diethylamide; Male; Melatonin; Methysergide; Norepinephrine; Phentolamine; Propranolol; Rats; Semen; Serotonin | 1972 |
Treatment of Parkinson's disease with levodopa combined with L-alpha-methyldopahydrazine, an inhibitor of extracerebral DOPA decarboxylase.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease | 1973 |
L-Dopa, B 6 , and alpha-methyldopa hydrazine.
Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbidopa; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease; Pyridoxine | 1973 |
An analysis of six patients with Parkinson's disease who have been unresponsive to L-dopa therapy.
Topics: Aged; Carbidopa; Diagnosis, Differential; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Male; Muscle Rigidity; Muscles; Neurologic Examination; Parkinson Disease; Tremor | 1973 |
Localization of the site of the central sympatho-inhibitory action of 1-Dopa in dogs and cats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Stem; Carbidopa; Cats; Clonidine; Decerebrate State; Dihydroxyphenylalanine; Dogs; Female; Heart Rate; Hydrazines; Injections, Intra-Arterial; Male; Splanchnic Nerves; Sympathetic Nervous System; Time Factors; Vertebral Artery | 1973 |
[Combination of L-dopa, desipramine, and a decarboxylase inhibitor in the treatment of depression (author's transl)].
Topics: Adult; Aged; Anxiety; Carbidopa; Carboxy-Lyases; Depression; Desipramine; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hydrazines; Male; Middle Aged | 1973 |
Metabolic interactions of pyridoxine, levodopa, and carbidopa in Parkinson's disease.
Topics: Brain; Carbidopa; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Homovanillic Acid; Humans; Hydrazines; Parkinson Disease; Pyridoxine | 1973 |
Urinary excretion of noradrenaline after treatment with alpha-methyldopa: inhibition by a central nervous mechanism.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Depression, Chemical; Epinephrine; Hydrazines; Injections, Intraperitoneal; Male; Methyldopa; Norepinephrine; Rats; Tritium | 1974 |
Transamination is a major pathway of L-dopa metabolism following peripheral decarboxylase inhibition.
Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Hydrazines; Phenylacetates; Transaminases | 1974 |
Levodopa, carbidopa, and pyridoxine in Parkinson disease. Metabolic interactions.
Topics: Carbidopa; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Drug Interactions; Drug Synergism; Homovanillic Acid; Humans; Hydrazines; Parkinson Disease; Pyridoxine | 1974 |
Carbidopa attenuation of L-DOPA emesis in dogs: evidence for a cerebral site of action outside the blood-brain barrier.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Binding Sites; Blood-Brain Barrier; Brain; Carbidopa; Cerebral Ventricles; Dihydroxyphenylalanine; Dogs; Dopamine; Emetics; Hydrazines; Injections; Injections, Intravenous | 1974 |
Carbidopa in Parkinson disease and in nausea and vomiting of levodopa.
Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Humans; Hydrazines; Male; Middle Aged; Nausea; Parkinson Disease; Vomiting | 1974 |
Parkinsonism-dementia of Guam: treatment with levodopa and L-alpha-methyldopahydrazine.
Topics: Adult; Aged; Carbidopa; Dementia; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Humans; Hydrazines; Male; Middle Aged; Pacific Islands; Parkinson Disease | 1974 |
"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine.
Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Injections, Intramuscular; Male; Methyldopa; Middle Aged; Movement Disorders; Parkinson Disease; Pyridoxine | 1974 |
Ro 4-4602 and levodopa in the treatment of Parkinsonism.
Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Basal Ganglia Diseases; Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Gastrointestinal Diseases; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease | 1974 |
Coupling of hypotensive and anit-Parkinson effects with two dopaminergic drugs.
Topics: Apomorphine; Blood Pressure; Brain; Carbidopa; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Hypotension; Parkinson Disease; Time Factors | 1971 |
Dopamine agonists in clinical research for new tardive dyskinesia treatments.
Topics: Adult; Aged; Antipsychotic Agents; Apomorphine; Benserazide; Carbidopa; Dopamine; Drug Combinations; Dyskinesia, Drug-Induced; Humans; Hydrazines; Levodopa; Middle Aged; Synaptic Transmission | 1983 |
Human pharmacokinetics of long term 5-hydroxytryptophan combined with decarboxylase inhibitors.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Platelets; Carbidopa; Drug Interactions; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Kinetics; Male; Middle Aged; Protein Binding | 1982 |
Effects of benserazide, carbidopa and isoniazid administration on tryptophan-nicotinamide nucleotide metabolism in the rat.
Topics: Animals; Benserazide; Body Weight; Carbidopa; Diet; Hydrazines; Isoniazid; Liver; Male; Niacinamide; Rats; Ribonucleotides; Time Factors; Tryptophan | 1980 |
Combined use of benserazide and carbidopa in Parkinson's disease.
Topics: Adult; Aged; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Outcome and Process Assessment, Health Care; Parkinson Disease | 1984 |
Response to Sinemet 25/100 in Parkinson's disease.
Topics: Aged; Benserazide; Body Weight; Carbidopa; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Sex Factors | 1984 |
[Treatment of patients with vascular parkinsonism with the preparations nakom and madopar].
Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Humans; Hydrazines; Levodopa; Middle Aged; Parkinson Disease, Secondary | 1984 |
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hydrazines; Middle Aged; Parkinson Disease; Schizophrenia; Tryptophan | 1982 |
Thyrotrophin and prolactin responses to thyrotrophin-releasing hormone in patients with Parkinson's disease.
Topics: Adult; Aged; Antiparkinson Agents; Benserazide; Carbidopa; Drug Combinations; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Prolactin; Thyrotropin; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine | 1982 |
The effect of some decarboxylase inhibitors on striatal tyramines in the mouse.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Carboxy-Lyases; Corpus Striatum; Hydrazines; Isomerism; Male; Mice; Tyramine | 1983 |
Prolactin response to acute administration of different L-dopa plus decarboxylase inhibitors in Parkinson's disease.
Topics: Aged; Animals; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Prolactin; Rats | 1982 |
Comparative 90-day toxicity of two decarboxylase inhibitors, benserazide and carbidopa, in the rat.
Topics: Animals; Benserazide; Blood; Bone and Bones; Carbidopa; Carboxy-Lyases; Dose-Response Relationship, Drug; Eating; Female; Growth Disorders; Hydrazines; Male; Organ Size; Radiography; Rats; Rats, Inbred Strains | 1982 |
Systemic and in vitro effects of GAD and GABA-T inhibitors on AADC activity and of AADC inhibitors on GAD.
Topics: 4-Aminobutyrate Transaminase; Adrenal Glands; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Benzyl Alcohols; Carbidopa; Carboxy-Lyases; Corpus Striatum; Female; Glutamate Decarboxylase; Hydrazines; Penicillamine; Rats; Transaminases | 1981 |
Effects of benserazide and carbidopa on the metabolism of L-tryptophan by isolated rat liver cells.
Topics: Alanine; Animals; Benserazide; Carbidopa; Chemical Phenomena; Chemistry; Hydrazines; Hydrolases; Liver; Oxidation-Reduction; Pyruvates; Rats; Tryptophan; Tryptophan Oxygenase | 1981 |
Dose and sex related effects of aromatic aminoacids decarboxylase inhibitors on serum prolactin in humans.
Topics: Administration, Oral; Adult; Age Factors; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dose-Response Relationship, Drug; Female; Humans; Hydrazines; Male; Prolactin; Sex Factors | 1980 |
Benserazide and carbidopa as substrates of catechol-O-methyltransferase: new mechanism of action in Parkinson's disease.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benserazide; Benzyl Compounds; Carbidopa; Catechol O-Methyltransferase; Hydrazines; Kinetics; Liver; Parkinson Disease; S-Adenosylmethionine; Substrate Specificity; Swine | 1980 |
Modulatory effects of L-DOPA on D2 dopamine receptors in rat striatum, measured using in vivo microdialysis and PET.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Carbon Radioisotopes; Corpus Striatum; Dopamine; Enzyme Inhibitors; gamma-Aminobutyric Acid; Globus Pallidus; Hydrazines; Kinetics; Levodopa; Male; Microdialysis; Raclopride; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D2; Salicylamides; Time Factors; Tomography, Emission-Computed | 1998 |
Voltammetric detection of L-dopa and carbidopa on graphene modified glassy carbon interfaces.
Topics: Carbidopa; Electrochemistry; Glass; Graphite; Hydrazines; Hydrogen-Ion Concentration; Levodopa; Nanostructures; Oxides | 2013 |
[(11)C]5-HTP and microPET are not suitable for pharmacodynamic studies in the rodent brain.
Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbidopa; Carbon Radioisotopes; Enzyme Inhibitors; Hydrazines; Male; Models, Biological; Positron-Emission Tomography; Rats; Rats, Wistar; Sensitivity and Specificity; Serotonin; Tissue Distribution; Tryptophan | 2014 |