carbidopa has been researched along with droxidopa in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (45.45) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 3 (13.64) | 29.6817 |
| 2010's | 5 (22.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Borge, GF; Buchsbaum, M; Maas, JW; Redmond, DE | 1 |
| Bartholini, J; Constantinidis, J; Pletscher, A; Puig, M; Tissot, R | 1 |
| Maas, JW; Olander, R; Redmond, DE | 1 |
| Bhardwaj, A; Brannan, T; Yahr, MD | 1 |
| Abe, T; Nozaki, Y; Takahashi, J; Takahashi, S; Tohgi, H; Ueno, M | 1 |
| Agmo, A; Picker, Z | 1 |
| Kato, T; Katsube, J; Katsuyama, M; Maeda, Y; Nakamura, M; Nishikawa, S | 1 |
| Ogawa, N; Ujike, H; Yamamoto, M | 1 |
| Reches, A | 1 |
| Higa, S; Kishimoto, S; Matsumoto, M; Sakoda, S; Suzuki, T; Ueji, M; Yoneda, S | 1 |
| Semba, J; Takahashi, R | 1 |
| Fahn, S; Jackson-Lewis, V; Reches, A | 1 |
| Hayashi, A; Kishimoto, S; Kondo, T; Narabayashi, H; Sakoda, S; Suzuki, T; Ueji, M | 1 |
| Abe, T; Takahashi, S; Tohgi, H | 1 |
| Freeman, R; Goldstein, DS; Holmes, C; Kaufmann, H; Nardin, R; Saadia, D; Voustianiouk, A; Yahr, MD | 1 |
| Jasmin, L; Narasaiah, M; Tien, D | 1 |
| Kaufmann, H | 1 |
| Goldstein, DS; Holmes, C; Kopin, IJ; Pechnik, S; Sewell, L | 1 |
| Nishijima, K; Saito, S; Shioda, K | 1 |
| Augustin, S; Brull, A; Coll, M; Esteban, R; Ezkurdia, N; Genescà, J; Guardia, J; Martell, M; Raurell, I; Rodriguez, S | 1 |
| Adler, LA; Gorny, SW | 1 |
| Goldstein, DS; Holmes, C; Lamotte, G; Sullivan, P | 1 |
2 review(s) available for carbidopa and droxidopa
| Article | Year |
|---|---|
Noradrenergic influences on dopaminergic function and the pharmacology of dihydroxyphenylserine (DOPS): implication for Parkinson's disease.
Topics: Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Carbidopa; Dopamine; Droxidopa; Levodopa; Locus Coeruleus; Myocardium; Norepinephrine; Pargyline; Parkinson Disease; Serine; Stereoisomerism; Tyrosine | 1985 |
L-dihydroxyphenylserine (Droxidopa): a new therapy for neurogenic orthostatic hypotension: the US experience.
Topics: Autonomic Nervous System Diseases; Blood Pressure; Carbidopa; Central Nervous System Diseases; Controlled Clinical Trials as Topic; Droxidopa; Humans; Hypotension, Orthostatic; Levodopa; Multiple System Atrophy; Norepinephrine; United States | 2008 |
2 trial(s) available for carbidopa and droxidopa
| Article | Year |
|---|---|
Norepinephrine precursor therapy in neurogenic orthostatic hypotension.
Topics: Administration, Oral; Aged; Antiparkinson Agents; Aromatic-L-Amino-Acid Decarboxylases; Blood Pressure; Carbidopa; Cross-Over Studies; Double-Blind Method; Droxidopa; Female; Hemodynamics; Humans; Hypotension, Orthostatic; Male; Middle Aged; Neurodegenerative Diseases; Norepinephrine; Posture; Single-Blind Method; Treatment Outcome | 2003 |
Effects of carbidopa and entacapone on the metabolic fate of the norepinephrine prodrug L-DOPS.
Topics: Aged; Antiparkinson Agents; Blood Pressure; Carbidopa; Catechols; Double-Blind Method; Droxidopa; Drug Interactions; Female; Humans; Male; Middle Aged; Multiple System Atrophy; Nitriles; Norepinephrine; Parkinson Disease; Prodrugs; Pure Autonomic Failure; Vasoconstriction | 2011 |
18 other study(ies) available for carbidopa and droxidopa
| Article | Year |
|---|---|
Evoked potential studies of brain catecholamine alterations in monkeys.
Topics: Animals; Brain; Brain Chemistry; Carbidopa; Catecholamines; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Droxidopa; Electrophysiology; Evoked Potentials; Female; Haplorhini; Macaca; Male; Methyltyrosines; Norepinephrine; Photic Stimulation | 1975 |
The stereoisomers of 3,4-dihydroxyphenylserine as precursors of norepinephrine.
Topics: Animals; Behavior, Animal; Benserazide; Brain; Brain Chemistry; Carbidopa; Carboxy-Lyases; Dopamine; Droxidopa; Female; Histocytochemistry; In Vitro Techniques; Male; Myocardium; Norepinephrine; Rats; Serine; Serotonin; Stereoisomerism | 1975 |
Cardiovascular effects of D,L-threo-dihydroxyphenylserine in cats.
Topics: Animals; Blood Pressure; Carbidopa; Cats; Droxidopa; Female; Heart Rate; Male; Norepinephrine; Serine; Time Factors | 1975 |
L-threodops increases extracellular norepinephrine levels in the brain: an in vivo study.
Topics: Animals; Carbidopa; Corpus Striatum; Droxidopa; Extracellular Space; Male; Norepinephrine; Rats; Rats, Inbred Strains; Serine | 1990 |
Effect of a synthetic norepinephrine precursor, L-threo-3,4- dihydroxyphenylserine on the total norepinephrine concentration in the cerebrospinal fluid of parkinsonian patients.
Topics: Carbidopa; Droxidopa; Humans; Levodopa; Middle Aged; Norepinephrine; Parkinson Disease | 1990 |
Catecholamines and the initiation of sexual behavior in male rats without sexual experience.
Topics: Animals; Benzylamines; Carbidopa; Dextroamphetamine; Dopamine; Dose-Response Relationship, Drug; Droxidopa; Flupenthixol; Male; Nalidixic Acid; Naphthyridines; Norepinephrine; Pimozide; Rats; Rats, Inbred Strains; Sexual Behavior, Animal | 1990 |
Diuretic effect of L-threo-3,4-dihydroxyphenylserine, a noradrenaline precursor, in rats and mice.
Topics: Animals; Benserazide; Carbidopa; Diuretics; Dose-Response Relationship, Drug; Droxidopa; Drug Interactions; Male; Mice; Norepinephrine; Rats; Rats, Inbred Strains; Serine; Species Specificity | 1986 |
Effect of L-threo-3,4-dihydroxyphenylserine chronic administration on cerebrospinal fluid and plasma free 3-methoxy-4-hydroxy-phenylglycol concentration in patients with Parkinson's disease.
Topics: Adult; Aged; Antiparkinson Agents; Carbidopa; Droxidopa; Drug Therapy, Combination; Glycols; Humans; Methoxyhydroxyphenylglycol; Middle Aged; Norepinephrine; Parkinson Disease; Serine | 1986 |
Treatment of orthostatic hypotension in Shy-Drager syndrome with DL-threo-3,4-dihydroxyphenylserine: a case report.
Topics: Autonomic Nervous System Diseases; Blood Pressure; Carbidopa; Droxidopa; Drug Combinations; Humans; Hypotension, Orthostatic; Male; Middle Aged; Norepinephrine; Phenylephrine; Serine; Shy-Drager Syndrome; Valsalva Maneuver | 1985 |
The effects of L-threo-dihydroxyphenylserine on norepinephrine metabolism in rat brain.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain; Carbidopa; Droxidopa; Fusaric Acid; Male; Methoxyhydroxyphenylglycol; Methyltyrosines; Norepinephrine; Rats; Rats, Inbred Strains; Reserpine; Serine | 1985 |
DL-threo-DOPS as a precursor of noradrenaline.
Topics: alpha-Methyltyrosine; Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Brain Chemistry; Carbidopa; Dopamine; Droxidopa; Levodopa; Male; Methyltyrosines; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Reserpine; Serine; Stereotyped Behavior | 1985 |
Treatment of parkinsonism with L-threo-3,4-dihydroxyphenylserine: a pharmacokinetic study.
Topics: Adult; Aged; Carbidopa; Cerebellar Diseases; Droxidopa; Female; Humans; Kinetics; Male; Middle Aged; Olivary Nucleus; Parkinson Disease; Pons; Serine | 1984 |
The effects of L-threo-3,4-dihydroxyphenylserine on the total norepinephrine and dopamine concentrations in the cerebrospinal fluid and freezing gait in parkinsonian patients.
Topics: Aged; Carbidopa; Dopamine; Dose-Response Relationship, Drug; Droxidopa; Female; Gait; Humans; Levodopa; Male; Middle Aged; Norepinephrine; Parkinson Disease | 1993 |
Noradrenaline is necessary for the hedonic properties of addictive drugs.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Appetitive Behavior; Benzazepines; Biphenyl Compounds; Bupropion; Carbidopa; Cocaine; Dopamine beta-Hydroxylase; Dopamine Uptake Inhibitors; Droxidopa; Female; Genotype; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; Morphine; Naltrexone; Narcotic Antagonists; Neurokinin-1 Receptor Antagonists; Norepinephrine; Receptors, Adrenergic, alpha-1; Receptors, Dopamine D1; Reward; Substance-Related Disorders | 2006 |
Dopamine dysregulation syndrome including mania related to coadministration of droxidopa.
Topics: Aggression; Antiparkinson Agents; Behavior, Addictive; Benzothiazoles; Bipolar Disorder; Carbidopa; Droxidopa; Drug Combinations; Drug Monitoring; Drug Therapy, Combination; Humans; Levodopa; Male; Middle Aged; Neurotoxicity Syndromes; Parkinson Disease; Pramipexole; Treatment Outcome | 2012 |
Droxidopa, an oral norepinephrine precursor, improves hemodynamic and renal alterations of portal hypertensive rats.
Topics: Animals; Antiparkinson Agents; Bile Ducts; Blood Pressure; Carbidopa; Carbon Tetrachloride; Disease Models, Animal; Diuresis; Droxidopa; Enzyme Inhibitors; Hemodynamics; Hypertension, Portal; Ligation; Liver Cirrhosis; Male; Natriuresis; Nitric Oxide Synthase Type III; Phosphorylation; Portal Vein; Propranolol; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Renal Circulation; rho-Associated Kinases; Signal Transduction; Urodynamics; Vascular Resistance | 2012 |
Pilot Study of Droxidopa With Carbidopa in Adults With ADHD.
Topics: Adult; Antiparkinson Agents; Attention Deficit Disorder with Hyperactivity; Carbidopa; Double-Blind Method; Droxidopa; Female; Humans; Male; Middle Aged; Pilot Projects; Treatment Outcome | 2019 |
Substantial renal conversion of L-threo-3,4-dihydroxyphenylserine (droxidopa) to norepinephrine in patients with neurogenic orthostatic hypotension.
Topics: Adult; Aged; Antiparkinson Agents; Carbidopa; Droxidopa; Drug Combinations; Female; Humans; Hypotension, Orthostatic; Kidney; Levodopa; Male; Middle Aged; Norepinephrine | 2019 |