carbidopa and dihydroxyphenylalanine

carbidopa has been researched along with dihydroxyphenylalanine in 139 studies

Research

Studies (139)

TimeframeStudies, this research(%)All Research%
pre-199085 (61.15)18.7374
1990's30 (21.58)18.2507
2000's9 (6.47)29.6817
2010's15 (10.79)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bellman, K; Knegtel, RM; Settimo, L1
Borison, RL; Giardina, WJ; Mosnaim, AD; Pedemonte, WA; Sabelli, HC; Vazquez, AJ1
Losey, EG; VonVoigtlander, PF1
Ogawa, M; Tohgi, H1
Watkins, CJ; Wiggins, JF; Wurtman, RJ1
Grimm, W; Schönberger, W; Ziegler, R2
Estey, E; Goldstein, M; Gopinathan, G; Lieberman, A; Ohashi, T; Sauter, A1
McDowell, FH; Miller, ST; Papavasiliou, PS; Rosal, V; Wang, YY1
Davidson, DL; Mawdsley, C; Pullar, IA; Wilson, H; Yates, CM1
Beerling-van der Molen, HD; Korf, J; Paans, AM; Reiffers, S; Ten Hoeve, W; Vaalburg, W; Woldring, MG; Wynberg, H1
Beerling-van der Molen, HD; Korf, J; Lakke, JP; Paans, AM; Reiffers, S; Vaalburg, W; Woldring, MG1
Jenner, PG; Jones, MK; Ramsay, ID1
Barkhatova, VP; Markova, ED1
Borge, GF; Buchsbaum, M; Maas, JW; Redmond, DE1
Watkins, CJ; Wurtman, RJ1
Mizuno, Y; Obayashi, T; Ueki, A; Yoshida, M1
Cohen, HP; Jacobson, RL; Martin, WE; Tolosa, ES1
Osborne, MW; Wenger, JJ1
Fellman, JH; Fujita, TS; Heriza, EL; Roth, ES1
Aigner, TG; Cohen, RM; Doudet, DJ; McLellan, CA1
Inglis, GC; Kenyon, CJ1
Aigner, TG; Cohen, RM; Doudet, DJ; McLellan, CA; Wyatt, RJ1
Barrio, JR; Grafton, SC; Hawk, TC; Hoffman, JM; Huang, SC; Luxen, A; Mahoney, DK; Mazziotta, JC; Melega, WP; Phelps, ME1
Aigner, TG; Brücke, T; Cohen, RM; Doudet, DJ; McLellan, CA1
Adam, MJ; Chan, GL; Hewitt, KA; Pate, BD; Ruth, TJ; Schofield, P1
Adams, HR; Aigner, TG; Cohen, RM; Doudet, DJ; Finn, RT; McLellan, CA; Miyake, H; Wyatt, R1
Barrio, JR; Grafton, ST; Huang, SC; Melega, WP; Phelps, ME; Satyamurthy, N1
Barrio, JR; Luxen, A; Melega, WP; Nissenson, CH; Perlmutter, MM; Phelps, ME1
Barrio, JR; Hoffman, JM; Luxen, A; Melega, WP; Nissenson, CH; Phelps, ME1
Cohen, G; Evans, JM1
Bazan, E; de Yebenes, JG; Mena, MA; Muradas, V; Reiriz, J1
Borisenko, SA; Burov, IuV; Kiianmaa, K; Lehtosalo, J; Mannisto, P1
Cedarbaum, JM; Dhar, AK; Kutt, H; McDowell, FH; Watkins, S1
Epstein, FH; Gunn, S; Landsberg, L; Rosa, RM; Williams, M; Young, JB1
Boyes, BE; Cumming, P; Martin, WR; McGeer, EG1
Cohen, G; Orosz, D1
Da Prada, M; Haefely, WE; Kettler, R; Schaffner, R; Zürcher, G1
Adam, MJ; Cumming, P; Grierson, J; Häusser, M; Martin, WR; McGeer, EG; Ruth, TJ1
Jeffrey, RF; Lee, MR; MacDonald, TM; Marwick, K1
Cannon-Spoor, E; Chuang, LW; Costa, E; Freed, WJ; Karoum, F; Wyatt, RJ1
Borisenko, SA1
Amanova, ZN; Badalian, LO; Grinio, ZN; Sadovskaia, IuE; Temin, PA1
Chase, TN; Fermaglich, J1
Chase, TN; Woods, AC1
Atkins, FL; Beaven, MA; Keiser, HR1
Bolme, P; Fuxe, K1
Clark, CM; Lotti, VJ; Stone, CA; Torchiana, ML1
Ahlenius, S1
Frigyesi, TL; Schwartz, R; Yahr, MD1
Strömberg, U; Waldeck, B1
Minsker, DH; Stokes, AL1
Sethy, VH; Van Woert, MH2
Henning, M; Pernevi, P; Trolin, G1
Fermaglich, J1
Porter, CC; Stone, CA; Torchiana, ML1
Malmnäs, CO1
Atkinson, JM; Schmitt, H; Sinha, JN1
Mones, RJ2
Olanow, CW; Schwartz, AM; Spencer, A1
Andrews, CJ; Somerville, B1
Friedman, E; Gershon, S1
Barry, PE; Marsden, CD; Parkes, JD; Zilkha, KJ1
Chase, TN; Donnelly, EF1
Klawans, HL; Ringel, SP1
Fenard, S; Schmitt, H1
Dinsmore, SR; Mrochek, JE; Ohrt, DW1
Calne, DB; Reid, JL1
Cotzias, GC; Lawrence, WH; Papavasiliou, PS1
Brody, JA; Chase, TN; Holden, EM2
Dick, P; Eisenring, JJ; Tissot, R; Yanniotis, G1
Mars, H2
Cardon, PV; Judy, WV; Watanabe, AM1
Calne, DB; Johnson, RD; Reid, JL; Ruthven, CR; Sandler, M1
Duvoisin, RC; Marsden, CD1
Fahn, S; Prasad, AL1
Clark, C; Lotti, VJ1
Diamond, SG; Markham, C; Treciokas, LJ1
Fuxe, K; Hökfelt, T; Johansson, O; Ljungdahl, A1
Fahn, S1
Miller, EM; Wiener, L1
Cotzias, GC; Dahl, LK; Düby, SE1
Gunder, M; Miller, S; Stewart, RM1
Beck, B; Brandt, NJ; Christensen, E; Niederwieser, A; Pedersen, PS1
Hiramatsu, M1
Anton, AH; Crumrine, RS; Izant, RJ; Stern, RC1
Baines, AD; Drangova, R1
Kawamura, M; Nakane, H; Saruta, T; Suzuki, H; Takeshita, E; Yoshizawa, M1
Beers, MF; Hurtig, H; Melvin, G; Scarpa, A; Stern, M1
Bonora, M; Gautier, H1
Anderson, GM; Chouinard, G; Gauthier, S; Purdy, WC; Young, SN1
Vartanian, KZ1
Lang, AE1
Ase, A; Cumming, P; Diksic, M; Gjedde, A; Harrison, J; Jolly, D; Kuwabara, H; Laliberté, C1
Eriksson, T; Holmgren, B1
Chan, GL; Dobko, T; Doudet, DJ; Hewitt, KA; Pate, BD; Ruth, TJ; Schofield, P1
Lang, A; Männistö, PT; Rauhala, P; Vasar, E1
Brooks, DJ; Burn, DJ; Lammertsma, AA; Luthra, S; Morrish, PK; Osman, S; Sawle, GV; Snow, BJ1
Dethy, S; Goldman, S; Luxen, A; Monclus, M; Pauwels, T1
Chrapusta, SJ; Egan, MF; Karoum, F; Wyatt, RJ1
Fukumura, T; Ichiya, Y; Kuwabara, Y; Masuda, K; Otsuka, M; Sasaki, M1
Cumming, P; Gjedde, A; Kuwabara, H; Léger, GC1
Bennett, JP; Schuh, LA1
Kaakkola, S; Wurtman, RJ1
Dubinsky, R; Hubble, JP; Koller, WC; Lyons, K; McGuire, D; Pahwa, R1
Ishii, S; Ishiwata, K; Nozaki, T; Senda, M; Shinoda, M1
Ashworth, S; Bloomfield, PM; Fricker, RA; Hume, SP; Jones, T; Lammertsma, AA; Myers, R; Rajeswaran, S; Torres, EM; Watson, I1
da Cruz Vieira, I; Fatibello-Filho, O1
Ase, A; Cumming, P; Gjedde, A; Kuwabara, H; Laliberté, C1
Brown, WD; DeJesus, OT; Holden, JE; Nickles, RJ; Oakes, TR; Roberts, AD; Taylor, MD1
Cumming, P; Danielsen, EH; Gee, AD; Gjedde, A; Hansen, SB; Hermansen, F; Smith, DF; Venkatachalam, TK1
Brousolle, E; Dentresangle, C; Froment, JC; Guerin, J; Lavenne, F; Le Bars, D; Pierre, C; Pollak, P; Veyre, L1
Blaschke, G; Chankvetadze, B; Saraç, S1
Dolezalová, M; Fanali, S1
Brus, R; Kostrzewa, JP; Kostrzewa, RM1
Ha, PT; Hauta-Aho, T; Hoogmartens, J; Roets, E; Van Schepdael, A1
Konno, R; Wang, YX; Wu, M; Zhou, XJ1
Adams, KT; Carrasquillo, JA; Chen, CC; Eisenhofer, G; Hadi, M; Ling, A; Martiniova, L; Pacak, K; Timmers, HJ; Whatley, M1
Kauhanen, S; Nuutila, P; Seppänen, M1
Cichoń, T; Frackowiak-Wojtasek, B; Gasowska-Bajger, B; Koj, S; Smolarczyk, R; Szala, S; Wojtasek, H1
Muhlack, S; Müller, T1
Abbs, JH; Bendlin, BB; Brooks, BR; Brown, WD; Chung, MK; Dejesus, OT; Dogan, S; Gallagher, CL; Holden, JE; Johnson, SC; Konopacki, RA; Nickles, RJ; Oakes, TR; Pyzalski, RW; Xu, G1
Chiti, A; D'Ambrosio, D; Fanti, S; Lopci, E; Marengo, M; Nanni, C; Pession, A1
Fukui, M; Kang, KS; Wen, Y; Yamabe, N; Zhu, BT1
Addeo, P; Averous, G; Bachellier, P; Imperiale, A; Namer, IJ1
Chondrogiannis, S; Marzola, MC; Rubello, D1
Santhanam, P; Taïeb, D1
Bachellier, P; Castinetti, F; Guillet, B; Imperiale, A; Kessler, L; Moreau, F; Mundler, O; Namer, IJ; Sebag, F; Taïeb, D; Vix, M1
Bachellier, P; Bahougne, T; Goichot, B; Imperiale, A; Namer, IJ; Taïeb, D1
Cardoso, MA; de Carvalho, KA; de Francisco, TM; de Oliveira Vilhena, R; Gasparetto, JC; Guimarães de Francisco, TM; Martins, CA; Pontarolo, R; Ribeiro, RP1
Harada, N; Kakiuchi, T; Kanazawa, M; Muramatsu, S; Ohba, H; Tsukada, H1
Bishnoi, P; Charde, SY; Raut, PP1
Boisson, F; Brasse, D; Detour, J; Imperiale, A; Kessler, L; Kreutter, G; Lavaux, T; Marchand, P; Namer, IJ; Pierre, A1
Boellaard, R; de Heide, LJ; de Vries, EG; Glaudemans, AW; Noordzij, W; Slart, RH; van Beek, AP; van der Horst-Schrivers, AN; van Ginkel, B1
Berger, E; El-Rabadi, K; Hacker, M; Haug, A; Karanikas, G; Nakuz, TS; Wadsak, W1

Reviews

4 review(s) available for carbidopa and dihydroxyphenylalanine

ArticleYear
Biochemical plasticity of synaptic transmission: a critical review of Dale's Principle.
    Biological psychiatry, 1976, Volume: 11, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Brain; Carbidopa; Deamination; Dihydroxyphenylalanine; Evoked Potentials; Humans; Mental Disorders; Methyldopa; Neural Inhibition; Neurons; Neurotransmitter Agents; Phenethylamines; Probenecid; Rabbits; Rats; Receptors, Drug; Synapses; Synaptic Transmission; Visual Perception

1976
Hemiatrophy, juvenile-onset exertional alternating leg paresis, hypotonia, and hemidystonia and adult-onset hemiparkinsonism: the spectrum of hemiparkinsonism-hemiatrophy syndrome.
    Movement disorders : official journal of the Movement Disorder Society, 1995, Volume: 10, Issue:4

    Topics: Antiparkinson Agents; Blood Glucose; Carbidopa; Contrast Media; Deoxyglucose; Dihydroxyphenylalanine; Dominance, Cerebral; Drug Combinations; Female; Fluorodeoxyglucose F18; Functional Laterality; Hemiplegia; Humans; Levodopa; Middle Aged; Muscle Hypotonia; Muscular Atrophy; Neurologic Examination; Parkinson Disease, Secondary; Physical Exertion; Substantia Nigra; Tomography, Emission-Computed

1995
¹⁸F-DOPA PET/computed tomography imaging.
    PET clinics, 2014, Volume: 9, Issue:3

    Topics: Abdomen; Carbidopa; Congenital Hyperinsulinism; Corpus Striatum; Digestive System; Dihydroxyphenylalanine; Fluorine Radioisotopes; Head; Humans; Neck; Neuroendocrine Cells; Positron-Emission Tomography; Radiopharmaceuticals; Thorax; Tissue Distribution; Tomography, X-Ray Computed; Whole Body Imaging

2014
Role of (18) F-FDOPA PET/CT imaging in endocrinology.
    Clinical endocrinology, 2014, Volume: 81, Issue:6

    Topics: Adrenal Gland Neoplasms; Carbidopa; Carcinoid Tumor; Carcinoma, Neuroendocrine; Dihydroxyphenylalanine; Dopamine Agents; Fluorodeoxyglucose F18; Humans; Multimodal Imaging; Neuroendocrine Tumors; Paraganglioma; Pheochromocytoma; Positron-Emission Tomography; Radiopharmaceuticals; Thyroid Neoplasms; Tomography, X-Ray Computed

2014

Trials

10 trial(s) available for carbidopa and dihydroxyphenylalanine

ArticleYear
[Effect of MK-486 alone on Parkinsonism; studies on the clinical symptoms and catecholamine concentrations in the blood, urine and cerebrospinal fluid].
    No to shinkei = Brain and nerve, 1977, Volume: 29, Issue:2

    Topics: Aged; Carbidopa; Catecholamines; Clinical Trials as Topic; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease

1977
Methyldopa or methyldopahydrazine as levodopa synergists.
    Lancet (London, England), 1973, Jun-02, Volume: 1, Issue:7814

    Topics: Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Methyldopa; Parkinson Disease

1973
Evaluation of alpha methyl dopa and alpha methyl dopa hydrazine with L-dopa therapy.
    New York state journal of medicine, 1974, Volume: 74, Issue:1

    Topics: Adult; Aged; Carbidopa; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazines; Methyldopa; Middle Aged; Parkinson Disease

1974
A double-blind controlled study of MK-486 in Parkinson's disease.
    Transactions of the American Neurological Association, 1973, Volume: 98

    Topics: Aged; Anorexia Nervosa; Antiparkinson Agents; Carbidopa; Clinical Trials as Topic; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Humans; Hydrazines; Male; Middle Aged; Nausea; Parkinson Disease; Placebos

1973
Levodopa combined with MK 486 (L-alpha methyldopahydrazine)--a peripheral decarboxylase inhibitor in Parkinson's disease.
    The Medical journal of Australia, 1974, Mar-23, Volume: 1, Issue:12

    Topics: Adult; Aged; Carbidopa; Carboxy-Lyases; Clinical Trials as Topic; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hydrazines; Male; Middle Aged; Movement Disorders; Nausea; Parkinson Disease; Placebos

1974
Intellectual and memory function in parkinsonian and non-parkinsonian patients treated with L-dopa.
    Diseases of the nervous system, 1973, Volume: 34, Issue:2

    Topics: Adult; Aged; Carbidopa; Dihydroxyphenylalanine; Educational Status; Female; Humans; Intelligence; Intelligence Tests; Male; Memory; Middle Aged; Parkinson Disease; Placebos; Psychological Tests

1973
The effect of entacapone (OR-611) on brain [18F]-6-L-fluorodopa metabolism: implications for levodopa therapy of Parkinson's disease.
    Neurology, 1994, Volume: 44, Issue:7

    Topics: Aged; Brain; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Drug Synergism; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Nitriles; Occipital Lobe; Parkinson Disease; Tomography, Emission-Computed

1994
Early morning akinesia in Parkinson's disease: effect of standard carbidopa/levodopa and sustained-release carbidopa/levodopa.
    Neurology, 1996, Volume: 46, Issue:4

    Topics: Aged; Carbidopa; Circadian Rhythm; Cross-Over Studies; Delayed-Action Preparations; Dihydroxyphenylalanine; Double-Blind Method; Drug Combinations; Female; Humans; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease

1996
The effects of carbidopa on uptake of 6-18F-Fluoro-L-DOPA in PET of pheochromocytoma and extraadrenal abdominal paraganglioma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:10

    Topics: Abdominal Neoplasms; Adrenal Gland Neoplasms; Carbidopa; Dihydroxyphenylalanine; Female; Humans; Image Enhancement; Male; Metabolic Clearance Rate; Middle Aged; Paraganglioma, Extra-Adrenal; Pheochromocytoma; Positron-Emission Tomography; Radiopharmaceuticals

2007
Feasibility of carbidopa premedication in pediatric patients: a pilot study.
    Cancer biotherapy & radiopharmaceuticals, 2012, Volume: 27, Issue:10

    Topics: Carbidopa; Child; Child, Preschool; Dihydroxyphenylalanine; Drug Interactions; Female; Fluorine Radioisotopes; Humans; Male; Neuroblastoma; Pilot Projects; Premedication; Radionuclide Imaging; Radiopharmaceuticals

2012

Other Studies

125 other study(ies) available for carbidopa and dihydroxyphenylalanine

ArticleYear
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
On the use of selective neurotoxic amine analogs to measure the blockade of norepinephrine and 5-hydroxytryptamine uptake systems by antidepressants.
    Research communications in chemical pathology and pharmacology, 1976, Volume: 13, Issue:3

    Topics: Animals; Antidepressive Agents; Brain; Carbidopa; Diazepam; Dihydroxyphenylalanine; Drug Interactions; Imipramine; Male; Methamphetamine; Mice; Neurons; Norepinephrine; Pargyline; Serotonin

1976
Carbidopa elevates hypothalamic dopa and serum prolactin in rats.
    Life sciences, 1979, Apr-30, Volume: 24, Issue:18

    Topics: Animals; Brain Chemistry; Carbidopa; Dihydroxyphenylalanine; Hypothalamus; Male; Median Eminence; Postmortem Changes; Prolactin; Pyridoxine; Rats; Time Factors

1979
[Improvement of growth-hormone stimulation with l-dopa/l-carbidopa by simultaneous administration of propranolol (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1979, Dec-21, Volume: 104, Issue:51

    Topics: Carbidopa; Child; Dihydroxyphenylalanine; Drug Therapy, Combination; Dwarfism; Growth Hormone; Humans; Propranolol

1979
Comparative effectiveness of two extracerebral DOPA decarboxylase inhibitors in Parkinson disease.
    Neurology, 1978, Volume: 28, Issue:9 Pt 1

    Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Carbidopa; Dihydroxyphenylalanine; Female; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease

1978
Plasma DOPA and growth hormone in parkinsonism: oscillations in symptoms.
    Neurology, 1979, Volume: 29, Issue:2

    Topics: Aged; Carbidopa; Dihydroxyphenylalanine; Female; Growth Hormone; Humans; Levodopa; Male; Middle Aged; Parkinson Disease

1979
CSF studies on the relationship between dopamine and 5-hydroxytryptamine in Parkinsonism and other movement disorders.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:12

    Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Hepatolenticular Degeneration; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Middle Aged; Movement Disorders; Parkinson Disease; Parkinson Disease, Postencephalitic; Serotonin; Tetrabenazine; Torticollis

1977
The effect of nacom (L-dopa and L-carbidopa) on growth hormone secretion in 75 patients with short stature.
    European journal of pediatrics, 1977, Dec-30, Volume: 127, Issue:1

    Topics: Adolescent; Arginine; Carbidopa; Child; Child, Preschool; Dihydroxyphenylalanine; Dwarfism; Growth Hormone; Humans; Hydrazines; Secretory Rate

1977
Rapid synthesis and purification of carbon-11 labelled DOPA: a potential agent for brain studies.
    The International journal of applied radiation and isotopes, 1977, Volume: 28, Issue:12

    Topics: Animals; Brain; Carbidopa; Carbon Radioisotopes; Dihydroxyphenylalanine; Male; Radionuclide Imaging; Rats

1977
Rapid decarboxylation of carbon-11 labelled DL-DOPA in the brain: a potential approach for external detection of nervous structures.
    Brain research, 1978, Apr-21, Volume: 145, Issue:1

    Topics: Animals; Brain; Brain Stem; Carbidopa; Carbon Radioisotopes; Cerebellum; Corpus Striatum; Dihydroxyphenylalanine; Hydroxydopamines; Male; Occipital Lobe; Premedication; Radionuclide Imaging; Rats; Receptors, Cholinergic; Receptors, Dopamine

1978
The effect of low dose carbidopa/levodopa on prolactin and growth hormone concentrations in patients with breast cancer and in benign breast tumours.
    British journal of clinical pharmacology, 1978, Volume: 5, Issue:5

    Topics: Adult; Aged; Breast Neoplasms; Carbidopa; Dihydroxyphenylalanine; Female; Growth Hormone; Humans; Hydrazines; Levodopa; Middle Aged; Prolactin; Thyroxine; Time Factors

1978
[Pathogenesis and treatment of torsion dystonia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1978, Volume: 78, Issue:8

    Topics: Carbidopa; Dihydroxyphenylalanine; Dopamine; Dystonia Musculorum Deformans; Epinephrine; Homovanillic Acid; Humans; Hydrazines; Jews; Levodopa; Norepinephrine; Vanilmandelic Acid

1978
Evoked potential studies of brain catecholamine alterations in monkeys.
    Journal of psychiatric research, 1975, Volume: 12, Issue:2

    Topics: Animals; Brain; Brain Chemistry; Carbidopa; Catecholamines; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Droxidopa; Electrophysiology; Evoked Potentials; Female; Haplorhini; Macaca; Male; Methyltyrosines; Norepinephrine; Photic Stimulation

1975
Suppression of noradrenaline synthesis in sympathetic nerves by carbidopa, an inhibitor of peripheral dopa decarboxylase.
    Nature, 1977, Jan-06, Volume: 265, Issue:5589

    Topics: Adrenergic Fibers; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Dihydroxyphenylalanine; Dopamine; Heart; Hydrazines; Male; Norepinephrine; Peripheral Nerves; Rats; Tyrosine

1977
[Combined treatment of Parkinsonism with L-dopa and peripheral dopa decarboxylase inhibitors--clinical course of 13 cases and levels of serum/dopa and dopamine].
    Rinsho shinkeigaku = Clinical neurology, 1976, Jul-01, Volume: 16, Issue:7

    Topics: Adult; Aged; Benserazide; Carbidopa; Dihydroxyphenylalanine; Dopamine; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease

1976
Patterns of clinical response and plasma dopa levels in Parkinson's disease.
    Neurology, 1975, Volume: 25, Issue:2

    Topics: Adult; Aged; Brain; Carbidopa; Dihydroxyphenylalanine; Disability Evaluation; Dose-Response Relationship, Drug; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Time Factors

1975
Effects of L-dopa on myocardial contractile force: a reappraisal.
    Archives internationales de pharmacodynamie et de therapie, 1975, Volume: 217, Issue:2

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Carbidopa; Cardiac Output; Dihydroxyphenylalanine; Dogs; Female; Heart Rate; Male; Myocardial Contraction; Time Factors

1975
Altered pattern of dopa metabolism.
    Biochemical pharmacology, 1976, Jan-15, Volume: 25, Issue:2

    Topics: Animals; Carbidopa; Cytosol; Dihydroxyphenylalanine; Hydrazines; Kidney; Kinetics; Liver; Mitochondria; Rats; Transaminases

1976
Positron emission tomography with 18F-dopa: interpretation and biological correlates in nonhuman primates.
    Psychiatry research, 1992, Volume: 45, Issue:3

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Carbidopa; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Macaca mulatta; Methoxyhydroxyphenylglycol; Parkinson Disease, Secondary; Receptors, Dopamine; Tomography, Emission-Computed

1992
Effects of long-term infusions of dopa and carbidopa on renin and steroid secretion in the rat.
    Endocrinology, 1992, Volume: 131, Issue:6

    Topics: Adrenal Cortex; Adrenal Cortex Hormones; Aldosterone; Animals; Carbidopa; Corticosterone; Desoxycorticosterone; Dihydroxyphenylalanine; Dopamine; Kidney; Male; Rats; Rats, Sprague-Dawley; Renin

1992
Delayed L-phenylalanine infusion allows for simultaneous kinetic analysis and improved evaluation of specific-to-nonspecific fluorine-18-dopa uptake in brain.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1992, Volume: 33, Issue:7

    Topics: Animals; Brain; Carbidopa; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Macaca mulatta; MPTP Poisoning; Phenylalanine; Time Factors; Tomography, Emission-Computed

1992
The effects of carbidopa administration on 6-[18F]fluoro-L-dopa kinetics in positron emission tomography.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1992, Volume: 33, Issue:8

    Topics: Adult; Animals; Carbidopa; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Injections, Intravenous; Macaca nemestrina; Male; Tomography, Emission-Computed

1992
New rapid analysis method demonstrates differences in 6-[18F] fluoro-L-dopa plasma input curves with and without carbidopa and in hemi-MPTP lesioned monkeys.
    International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes, 1991, Volume: 42, Issue:9

    Topics: Animals; Carbidopa; Dihydroxyphenylalanine; Dopamine; Fluorine Radioisotopes; Functional Laterality; Kinetics; Macaca mulatta; MPTP Poisoning; Reference Values; Synapses; Time Factors

1991
Routine determination of [18F]-L-6-fluorodopa and its metabolites in blood plasma is essential for accurate positron emission tomography studies.
    Life sciences, 1992, Volume: 50, Issue:4

    Topics: Adsorption; Age Factors; Aluminum Oxide; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Tomography, Emission-Computed; Tyrosine

1992
Postinjection L-phenylalanine increases basal ganglia contrast in PET scans of 6-18F-DOPA.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1991, Volume: 32, Issue:7

    Topics: Animals; Basal Ganglia; Carbidopa; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Macaca mulatta; Male; Phenylalanine; Time Factors; Tomography, Emission-Computed

1991
L-6-[18F]fluoro-dopa metabolism in monkeys and humans: biochemical parameters for the formulation of tracer kinetic models with positron emission tomography.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1991, Volume: 11, Issue:6

    Topics: Adult; Animals; Blood Chemical Analysis; Brain; Carbidopa; Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Macaca nemestrina; Male; Tissue Distribution; Tomography, Emission-Computed

1991
Comparative in vivo metabolism of 6-[18F]fluoro-L-dopa and [3H]L-dopa in rats.
    Biochemical pharmacology, 1990, Jun-15, Volume: 39, Issue:12

    Topics: Animals; Brain; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fluorine Radioisotopes; Injections, Intravenous; Kinetics; Levodopa; Male; Rats; Rats, Inbred Strains; Tritium

1990
The effects of carbidopa on the metabolism of 6-[18F]fluoro-L-dopa in rats, monkeys and humans.
    Life sciences, 1990, Volume: 47, Issue:2

    Topics: Adult; Animals; Carbidopa; Cerebellum; Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Macaca fascicularis; Male; Rats; Rats, Inbred Strains

1990
Studies on the formation of 6-hydroxydopamine in mouse brain after administration of 2,4,5-trihydroxyphenylalanine (6-hydroxyDOPA).
    Journal of neurochemistry, 1989, Volume: 52, Issue:5

    Topics: Animals; Brain; Carbidopa; Cerebral Cortex; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Frontal Lobe; Hydroxydopamines; Male; Mice; Norepinephrine; Oxidopamine; Pargyline; Reserpine; Synaptic Vesicles

1989
Pharmacokinetics of L-dopa in patients with Parkinson's disease.
    Advances in neurology, 1987, Volume: 45

    Topics: Biotransformation; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disability Evaluation; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Humans; Kinetics; Levodopa; Methyldopa; Parkinson Disease; Receptors, Dopamine; Receptors, Dopamine D2; Tiapamil Hydrochloride

1987
[Effect of a single ethanol administration on the permeability of the hemato-encephalic barrier for 14C-tyrosine, 14C-DOPA and horseradish peroxidase].
    Biulleten' eksperimental'noi biologii i meditsiny, 1986, Volume: 101, Issue:3

    Topics: Animals; Biological Transport; Blood-Brain Barrier; Brain; Carbidopa; Carbon Radioisotopes; Cell Membrane Permeability; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Ethanol; Horseradish Peroxidase; Male; Peroxidases; Rats; Rats, Inbred Strains; Tyrosine

1986
Effect of supplemental carbidopa on bioavailability of L-dopa.
    Clinical neuropharmacology, 1986, Volume: 9, Issue:2

    Topics: Aged; Biological Availability; Carbidopa; Dihydroxyphenylalanine; Drug Administration Schedule; Humans; Levodopa; Parkinson Disease

1986
Effect of protein ingestion on urinary dopamine excretion. Evidence for the functional importance of renal decarboxylation of circulating 3,4-dihydroxyphenylalanine in man.
    The Journal of clinical investigation, 1986, Volume: 78, Issue:6

    Topics: Adult; Aldosterone; Analysis of Variance; Body Water; Carbidopa; Creatinine; Decarboxylation; Dietary Proteins; Dihydroxyphenylalanine; Dopamine; Humans; Kidney; Male; Norepinephrine; Potassium; Sodium

1986
Determination of plasma [18F]-6-fluorodopa during positron emission tomography: elimination and metabolism in carbidopa treated subjects.
    Life sciences, 1986, Dec-08, Volume: 39, Issue:23

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Age Factors; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dystonia; Humans; Kinetics; Metabolic Clearance Rate; Parkinson Disease; Pyridines; Tomography, Emission-Computed

1986
Decarboxylation of DL-2,4-dihydroxyphenylalanine (2,4-DOPA) to 2,4-dihydroxyphenylethylamine in mouse striatal slices.
    European journal of pharmacology, 1987, Apr-29, Volume: 136, Issue:3

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Chromatography, High Pressure Liquid; Corpus Striatum; Decarboxylation; Dihydroxyphenylalanine; In Vitro Techniques; Male; Mice; Phenethylamines

1987
Inhibition of decarboxylase and levels of dopa and 3-O-methyldopa: a comparative study of benserazide versus carbidopa in rodents and of Madopar standard versus Madopar HBS in volunteers.
    European neurology, 1987, Volume: 27 Suppl 1

    Topics: Administration, Oral; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Aromatic-L-Amino-Acid Decarboxylases; Benserazide; Brain; Carbidopa; Delayed-Action Preparations; Dihydroxyphenylalanine; Dogs; Dopa Decarboxylase; Dose-Response Relationship, Drug; Drug Combinations; Humans; Hydrazines; Kidney; Levodopa; Liver; Male; Mice; Rats; Time Factors; Tyrosine

1987
Kinetics of in vitro decarboxylation and the in vivo metabolism of 2-18F- and 6-18F-fluorodopa in the hooded rat.
    Biochemical pharmacology, 1988, Jan-15, Volume: 37, Issue:2

    Topics: Animals; Carbidopa; Corpus Striatum; Decarboxylation; Dihydroxyphenylalanine; Fluorine Radioisotopes; In Vitro Techniques; Kinetics; Male; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Tissue Distribution

1988
The effect of carbidopa and indomethacin on the renal response to gamma-L-glutamyl-L-dopa in normal man.
    British journal of clinical pharmacology, 1988, Volume: 25, Issue:2

    Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Dopamine; Humans; Indomethacin; Kallikreins; Kidney; Male; Renin; Sodium

1988
D-dopa and L-dopa similarly elevate brain dopamine and produce turning behavior in rats.
    Brain research, 1988, Feb-02, Volume: 440, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Carbidopa; Cerebral Ventricles; Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Levodopa; Male; Rats; Rats, Inbred Strains; Stereotyped Behavior; Structure-Activity Relationship

1988
[Effect of carbidopa and dimethyl sulfoxide on the permeability of the hemato-encephalic barrier for 14C-tyrosine and 14C-DOPA in rats].
    Biulleten' eksperimental'noi biologii i meditsiny, 1988, Volume: 106, Issue:12

    Topics: Animals; Blood-Brain Barrier; Brain; Carbidopa; Carbon Radioisotopes; Cell Membrane Permeability; Dihydroxyphenylalanine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Male; Rats; Rats, Inbred Strains; Tyrosine

1988
[Effect of the test with the drug Nakom on the dynamics of excretion of catecholamines and DOPA in children with Duchenne's progressive muscular dystrophy].
    Pediatriia, 1985, Issue:5

    Topics: Adolescent; Carbidopa; Catecholamines; Child; Child, Preschool; Circadian Rhythm; Dihydroxyphenylalanine; Drug Combinations; Humans; Levodopa; Muscular Dystrophies

1985
M.I.F.: effect on levodopa dyskinesias in man.
    Lancet (London, England), 1973, Sep-01, Volume: 2, Issue:7827

    Topics: Antiparkinson Agents; Carbidopa; Carboxy-Lyases; Decarboxylation; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Humans; Melanocyte-Stimulating Hormones; Methylation; Movement Disorders; Parkinson Disease

1973
Dopa decarboxylase in medullary carcinoma of the thyroid.
    The New England journal of medicine, 1973, Sep-13, Volume: 289, Issue:11

    Topics: Adrenal Gland Neoplasms; Amine Oxidase (Copper-Containing); Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Carcinoma; Cresols; Dihydroxyphenylalanine; Dopa Decarboxylase; Histamine; Histidine; Humans; Hydrazines; Hydroxylamines; Methyldopa; Methylhistidines; Norepinephrine; Pheochromocytoma; Serotonin; Thyroid Gland; Thyroid Neoplasms; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase

1973
Pharmacological studies on a possible role of central noradrenaline neurons in respiratory control.
    The Journal of pharmacy and pharmacology, 1973, Volume: 25, Issue:4

    Topics: Amines; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benzyl Compounds; Carbidopa; Clonidine; Depression, Chemical; Dihydroxyphenylalanine; Dopamine; Guanidines; Male; Neurons; Norepinephrine; Rats; Respiration; Time Factors

1973
Comparison of centrally mediated hypotensive action of methyldopa and DOPA in cats.
    Archives internationales de pharmacodynamie et de therapie, 1973, Volume: 205, Issue:1

    Topics: Adrenergic alpha-Antagonists; Amino Acids; Animals; Antihypertensive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benzoates; Blood Pressure; Carbidopa; Cats; Cerebral Ventricles; Dihydroxyphenylalanine; Disulfides; Dopamine beta-Hydroxylase; Female; Imidazoles; Male; Methyldopa; Perfusion; Phentolamine; Pyrimidines; Spiro Compounds; Sulfhydryl Compounds; Time Factors

1973
Reversal by L-DOPA of the suppression of locomotor activity induced by inhibition of tyrosine-hydroxylase and DA-beta-hydroxylase in mice.
    Brain research, 1974, Mar-29, Volume: 69, Issue:1

    Topics: Animals; Brain; Carbidopa; Dihydroxyphenylalanine; Disulfides; Dopamine; Dopamine beta-Hydroxylase; Female; Imidazoles; Locomotion; Methyltyrosines; Mice; Norepinephrine; Reserpine; Synaptic Transmission; Tritium; Tyrosine 3-Monooxygenase

1974
Electrophysiological analysis of the effects of L-dopa on the reciprocal corticothalamic projections in the squirrel monkey. I. Iatrogenic coma and disinhibition of medial thalamic neurons.
    Journal of neural transmission, 1974, Volume: 35, Issue:2

    Topics: Animals; Carbidopa; Caudate Nucleus; Coma; Dihydroxyphenylalanine; Disease Models, Animal; Electric Stimulation; Electroencephalography; Evoked Potentials; Haplorhini; Motor Cortex; Neural Inhibition; Neural Pathways; Thalamic Nuclei; Thalamus

1974
Further studies on the behavioural and biochemical interaction between caffeine and L-DOPA.
    Journal of neural transmission, 1973, Volume: 34, Issue:4

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Caffeine; Carbidopa; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Hydroxyindoleacetic Acid; Locomotion; Mice; Motor Activity; Norepinephrine; Receptors, Adrenergic; Serotonin; Synaptic Transmission; Tritium; Tyrosine

1973
Aterial blood pressure in dogs: effects of m-tyrosine alone or in combination with inhibitors of aromatic amino acid decarboxylase; relative hypotensive potencies of L-dopa, DL-m-tyrosine, and L-m-tyrosine.
    Experientia, 1974, Sep-15, Volume: 30, Issue:9

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Carbidopa; Dihydroxyphenylalanine; Dogs; Female; Heart Rate; Hydrazines; Male; Tyrosine

1974
Regulation of striatal acetylcholine concentration by dopamine receptors.
    Nature, 1974, Oct-11, Volume: 251, Issue:5475

    Topics: Acetylcholine; Animals; Apomorphine; Brain Chemistry; Carbidopa; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Haloperidol; Male; Pimozide; Rats; Receptors, Adrenergic

1974
Spinal noradrenaline mechanisms and blood pressure: effect of local treatment with 6-hydroxydopamine in the rat.
    Medical biology, 1974, Volume: 52, Issue:5

    Topics: Animals; Blood Pressure; Carbidopa; Clonidine; Depression, Chemical; Dihydroxyphenylalanine; Heart Rate; Hydroxydopamines; Male; Norepinephrine; Rats; Reflex; Spinal Cord; Stimulation, Chemical; Time Factors

1974
Treatment of Parkinson's disease with carbidopa, a peripheral decarboxylase inhibitor, and levodopa.
    The Medical annals of the District of Columbia, 1974, Volume: 43, Issue:12

    Topics: Aged; Carbidopa; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease

1974
(S)-norepinephrine in the tissues of mice and rats given racemic erythro-3,4-dihydroxyphenylserine (DOPS).
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, Aug-15, Volume: 11, Issue:16

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain; Brain Chemistry; Carbidopa; Catechols; Decarboxylation; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Dose-Response Relationship, Drug; Female; Kidney; Male; Mice; Myocardium; Norepinephrine; Rats; Serine; Stereoisomerism; Structure-Activity Relationship; Tyramine

1972
Monoamine precursors and copulatory behavior in the male rat.
    Acta physiologica Scandinavica. Supplementum, 1973, Volume: 400

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Carbidopa; Carboxy-Lyases; Castration; Copulation; Depression, Chemical; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Ejaculation; Female; Hydrazines; Injections, Intraperitoneal; Male; Monoamine Oxidase Inhibitors; Motor Activity; Nialamide; Pargyline; Rats; Sexual Behavior, Animal; Stimulation, Chemical; Testosterone; Time Factors

1973
Effects of clonidine and L-dopa on spontaneous and evoked splanchnic nerve discharges.
    European journal of pharmacology, 1973, Volume: 24, Issue:1

    Topics: Animals; Blood Pressure; Carbidopa; Cats; Clonidine; Dihydroxyphenylalanine; Electric Stimulation; Evoked Potentials; Female; Heart Rate; Hypothalamus; Laminectomy; Male; Medulla Oblongata; Norepinephrine; Pressoreceptors; Receptors, Adrenergic; Sciatic Nerve; Spinal Cord; Splanchnic Nerves; Stereotaxic Techniques; Sympatholytics; Yohimbine

1973
L-DOPA: centrally mediated emission of seminal fluid in male rats.
    Life sciences. Pt. 1: Physiology and pharmacology, 1972, May-01, Volume: 11, Issue:9

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Atropine; Benserazide; Carbidopa; Cyproheptadine; Dihydroxyphenylalanine; Dopamine; Ejaculation; Haloperidol; Hydrazines; Hypophysectomy; Lysergic Acid Diethylamide; Male; Melatonin; Methysergide; Norepinephrine; Phentolamine; Propranolol; Rats; Semen; Serotonin

1972
Treatment of Parkinson's disease with levodopa combined with L-alpha-methyldopahydrazine, an inhibitor of extracerebral DOPA decarboxylase.
    Journal of neurology, neurosurgery, and psychiatry, 1973, Volume: 36, Issue:1

    Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease

1973
L-Dopa, B 6 , and alpha-methyldopa hydrazine.
    Confinia neurologica, 1973, Volume: 35, Issue:3

    Topics: Adult; Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Carbidopa; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease; Pyridoxine

1973
An analysis of six patients with Parkinson's disease who have been unresponsive to L-dopa therapy.
    Journal of neurology, neurosurgery, and psychiatry, 1973, Volume: 36, Issue:3

    Topics: Aged; Carbidopa; Diagnosis, Differential; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Male; Muscle Rigidity; Muscles; Neurologic Examination; Parkinson Disease; Tremor

1973
Localization of the site of the central sympatho-inhibitory action of 1-Dopa in dogs and cats.
    European journal of pharmacology, 1973, Volume: 22, Issue:2

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Brain Stem; Carbidopa; Cats; Clonidine; Decerebrate State; Dihydroxyphenylalanine; Dogs; Female; Heart Rate; Hydrazines; Injections, Intra-Arterial; Male; Splanchnic Nerves; Sympathetic Nervous System; Time Factors; Vertebral Artery

1973
Monitoring phenylalanine-tyrosine metabolism by high-resolution liquid chromatography of urine.
    Clinical chemistry, 1973, Volume: 19, Issue:8

    Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Autistic Disorder; Carbidopa; Catechols; Child; Chromatography, Gas; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Hippurates; Homovanillic Acid; Humans; Hyperkinesis; Intellectual Disability; Lactates; Mandelic Acids; Mass Spectrometry; Methods; Nervous System Diseases; Parkinson Disease; Phenylacetates; Phenylalanine; Spectrophotometry, Ultraviolet; Tyrosine

1973
Actions of levodopa on the blood pressure of conscious rabbits.
    British journal of pharmacology, 1973, Volume: 48, Issue:2

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Blood Pressure; Carbidopa; Dihydroxyphenylalanine; Iproniazid; Male; Monoamine Oxidase Inhibitors; Rabbits; Time Factors

1973
Levodopa and dopamine in cerebrospinal fluid.
    Neurology, 1973, Volume: 23, Issue:7

    Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Benztropine; Carbidopa; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Evaluation Studies as Topic; Female; Humans; Male; Middle Aged; Parkinson Disease; Pyridoxine; Spinal Puncture; Trihexyphenidyl

1973
Levodopa-induced dyskinesias. Comparison in Parkinsonism-dementia and amyotrophic lateral sclerosis.
    Archives of neurology, 1973, Volume: 29, Issue:5

    Topics: Adult; Aged; Amyotrophic Lateral Sclerosis; Carbidopa; Dementia; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Movement Disorders; Parkinson Disease

1973
[Combination of L-dopa, desipramine, and a decarboxylase inhibitor in the treatment of depression (author's transl)].
    Psychopharmacologia, 1973, Oct-23, Volume: 33, Issue:1

    Topics: Adult; Aged; Anxiety; Carbidopa; Carboxy-Lyases; Depression; Desipramine; Dihydroxyphenylalanine; Drug Therapy, Combination; Female; Humans; Hydrazines; Male; Middle Aged

1973
Metabolic interactions of pyridoxine, levodopa, and carbidopa in Parkinson's disease.
    Transactions of the American Neurological Association, 1973, Volume: 98

    Topics: Brain; Carbidopa; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Homovanillic Acid; Humans; Hydrazines; Parkinson Disease; Pyridoxine

1973
Effect of L-DOPA on blood pressure and sympathetic nerve activity after decarboxylase inhibition in cats.
    The Journal of pharmacology and experimental therapeutics, 1974, Volume: 188, Issue:1

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Autonomic Fibers, Postganglionic; Autonomic Fibers, Preganglionic; Blood Pressure; Carbidopa; Cats; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Heart; Heart Rate; In Vitro Techniques; Kidney; Neurons; Pressoreceptors; Splanchnic Nerves; Sympathetic Nervous System; Time Factors

1974
Transamination is a major pathway of L-dopa metabolism following peripheral decarboxylase inhibition.
    Nature, 1974, Feb-08, Volume: 247, Issue:5440

    Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Dihydroxyphenylalanine; Homovanillic Acid; Humans; Hydrazines; Phenylacetates; Transaminases

1974
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
    Brain research, 1974, May-10, Volume: 71, Issue:1

    Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Methyldopa; Mice; Movement Disorders; Parkinson Disease; Phenoxybenzamine; Pimozide; Reserpine

1974
3-O-methyl metabolites of catecholamines: automated fluorometric assay and their plasma levels in patients receiving levodopa and carbidopa.
    Biochemical medicine, 1974, Volume: 9, Issue:2

    Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Autoanalysis; Blood-Brain Barrier; Brain Chemistry; Carbidopa; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Dopamine; Evaluation Studies as Topic; Homovanillic Acid; Humans; Methods; Methyldopa; Microchemistry; Phenylacetates; Spectrometry, Fluorescence; Time Factors

1974
Levodopa, carbidopa, and pyridoxine in Parkinson disease. Metabolic interactions.
    Archives of neurology, 1974, Volume: 30, Issue:6

    Topics: Carbidopa; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Drug Interactions; Drug Synergism; Homovanillic Acid; Humans; Hydrazines; Parkinson Disease; Pyridoxine

1974
Carbidopa attenuation of L-DOPA emesis in dogs: evidence for a cerebral site of action outside the blood-brain barrier.
    European journal of pharmacology, 1974, Volume: 25, Issue:3

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Binding Sites; Blood-Brain Barrier; Brain; Carbidopa; Cerebral Ventricles; Dihydroxyphenylalanine; Dogs; Dopamine; Emetics; Hydrazines; Injections; Injections, Intravenous

1974
Carbidopa in Parkinson disease and in nausea and vomiting of levodopa.
    Archives of neurology, 1974, Volume: 31, Issue:2

    Topics: Aged; Athetosis; Carbidopa; Chorea; Dihydroxyphenylalanine; Evaluation Studies as Topic; Female; Humans; Hydrazines; Male; Middle Aged; Nausea; Parkinson Disease; Vomiting

1974
Modification of striatal acetylcholine concentration by dopamine receptor agonists and antagonists.
    Research communications in chemical pathology and pharmacology, 1974, Volume: 8, Issue:1

    Topics: Acetylcholine; Amphetamine; Animals; Apomorphine; Aromatic Amino Acid Decarboxylase Inhibitors; Brain Chemistry; Brain Stem; Carbidopa; Cerebral Cortex; Chlorpromazine; Corpus Striatum; Dextroamphetamine; Dibenzazepines; Dihydroxyphenylalanine; Dioxoles; Dopamine; Drug Synergism; Haloperidol; Hippocampus; Hypothalamus; Male; Pimozide; Piperazines; Pyrimidines; Rats; Receptors, Drug; Thalamus; Time Factors

1974
Parkinsonism-dementia of Guam: treatment with levodopa and L-alpha-methyldopahydrazine.
    Neurology, 1974, Volume: 24, Issue:3

    Topics: Adult; Aged; Carbidopa; Dementia; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Humans; Hydrazines; Male; Middle Aged; Pacific Islands; Parkinson Disease

1974
Dopamine nerve terminals in the rat limbic cortex: aspects of the dopamine hypothesis of schizophrenia.
    Science (New York, N.Y.), 1974, Apr-12, Volume: 184, Issue:4133

    Topics: Animals; Carbidopa; Dihydroxyphenylalanine; Disulfides; Dopamine; Dopamine beta-Hydroxylase; Humans; Imidazoles; Limbic System; Male; Microscopy, Fluorescence; Rats; Receptors, Drug; Reserpine; Schizophrenia

1974
"On-off" phenomenon with levodopa therapy in Parkinsonism. Clinical and pharmacologic correlations and the effect of intramuscular pyridoxine.
    Neurology, 1974, Volume: 24, Issue:5

    Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Homovanillic Acid; Humans; Hydrazines; Injections, Intramuscular; Male; Methyldopa; Middle Aged; Movement Disorders; Parkinson Disease; Pyridoxine

1974
Ro 4-4602 and levodopa in the treatment of Parkinsonism.
    Neurology, 1974, Volume: 24, Issue:5

    Topics: Aged; Aromatic Amino Acid Decarboxylase Inhibitors; Basal Ganglia Diseases; Carbidopa; Dihydroxyphenylalanine; Drug Synergism; Evaluation Studies as Topic; Female; Gastrointestinal Diseases; Humans; Hydrazines; Male; Middle Aged; Parkinson Disease

1974
Coupling of hypotensive and anit-Parkinson effects with two dopaminergic drugs.
    Transactions of the Association of American Physicians, 1971, Volume: 84

    Topics: Apomorphine; Blood Pressure; Brain; Carbidopa; Carboxy-Lyases; Dihydroxyphenylalanine; Drug Synergism; Humans; Hydrazines; Hypotension; Parkinson Disease; Time Factors

1971
Urinary 5-S-cysteinyldopa in Parkinsonism after DOPA and carbidopa.
    Acta dermato-venereologica, 1983, Volume: 63, Issue:2

    Topics: Adult; Aged; Carbidopa; Cysteinyldopa; Dihydroxyphenylalanine; Humans; Melanoma; Middle Aged; Parkinson Disease; Skin Neoplasms

1983
Diagnostic and therapeutic aspects of dihydrobiopterin deficiency.
    Acta paediatrica Scandinavica, 1983, Volume: 72, Issue:3

    Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Humans; Infant; Male; Nervous System Diseases; Phenylalanine; Phenylketonurias; Pteridines

1983
Brain 5-hydroxytryptamine level, metabolism, and binding in E1 mice.
    Neurochemical research, 1983, Volume: 8, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbidopa; Dihydroxyphenylalanine; Mice; Mice, Inbred Strains; Monoamine Oxidase; Physical Stimulation; Serotonin

1983
Inhibition of catecholamine biosynthesis by carbidopa and metyrosine in neuroblastoma.
    Pediatric pharmacology (New York, N.Y.), 1983, Volume: 3, Issue:2

    Topics: alpha-Methyltyrosine; Carbidopa; Catecholamines; Child, Preschool; Dihydroxyphenylalanine; Dopamine; Female; Homovanillic Acid; Humans; Infant; Male; Methyltyrosines; Neuroblastoma; Norepinephrine; Vanilmandelic Acid

1983
Dopamine production by the isolated perfused rat kidney.
    Canadian journal of physiology and pharmacology, 1984, Volume: 62, Issue:3

    Topics: Animals; Carbidopa; Catecholamines; Denervation; Dihydroxyphenylalanine; Dopamine; In Vitro Techniques; Kidney; Male; Neurons; Rats; Rats, Inbred Strains; Time Factors; Tyrosine

1984
Excretion and metabolism of dopa and dopamine by isolated perfused rat kidney.
    The American journal of physiology, 1984, Volume: 247, Issue:3 Pt 1

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Dihydroxyphenylalanine; Dopamine; Glomerular Filtration Rate; Kidney; Kidney Glomerulus; Male; Perfusion; Rats; Rats, Inbred Strains

1984
Simultaneous determination of L-dopa and 3-O-methyldopa in human serum by high-performance liquid chromatography.
    Journal of chromatography, 1984, Dec-12, Volume: 336, Issue:2

    Topics: Adult; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Epinephrine; Humans; Levodopa; Male; Methyltyrosines; Norepinephrine; Parkinson Disease; Tyrosine

1984
Possible alterations in brain monoamine metabolism during hypoxia-induced tachypnea in cats.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1980, Volume: 49, Issue:5

    Topics: Aminophylline; Animals; Biogenic Amines; Brain; Caffeine; Carbidopa; Cats; Dihydroxyphenylalanine; Doxapram; Hypercapnia; Hypoxia; Respiration Disorders

1980
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
    Journal of neural transmission, 1982, Volume: 53, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hydrazines; Middle Aged; Parkinson Disease; Schizophrenia; Tryptophan

1982
[Biochemical evaluation of the effectiveness of antiparkinson preparations containing L-DOPA].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:12

    Topics: Carbidopa; Dihydroxyphenylalanine; Dopamine; Drug Combinations; Epinephrine; Humans; Levodopa; Norepinephrine; Parkinson Disease

1981
Metabolism and blood-brain clearance of L-3,4-dihydroxy-[3H]phenylalanine ([3H]DOPA) and 6-[18F]fluoro-L-DOPA in the rat.
    Biochemical pharmacology, 1995, Sep-28, Volume: 50, Issue:7

    Topics: Animals; Blood-Brain Barrier; Carbidopa; Dihydroxyphenylalanine; Fluorine Radioisotopes; Male; Methylation; Rats; Rats, Wistar; Tritium

1995
Rapid degradation of 3,4-dihydroxyphenylalanine in plasma samples containing ethylenediaminetetraacetic acid.
    Clinica chimica acta; international journal of clinical chemistry, 1995, Jul-14, Volume: 238, Issue:2

    Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Blood Specimen Collection; Carbidopa; Chelating Agents; Dihydroxyphenylalanine; Dopamine Agents; Edetic Acid; Humans; Levodopa; Temperature

1995
Routes of administration and effect of carbidopa pretreatment on 6-[18F]fluoro-L-dopa/PET scans in non-human primates.
    Life sciences, 1995, Volume: 56, Issue:21

    Topics: Administration, Oral; Animals; Carbidopa; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Injections, Intraperitoneal; Injections, Intravenous; Intubation, Gastrointestinal; Macaca fascicularis; Premedication; Time Factors; Tomography, Emission-Computed

1995
Beneficial effects of co-administration of catechol-O-methyltransferase inhibitors and L-dihydroxyphenylalanine in rat models of depression.
    European journal of pharmacology, 1995, Feb-14, Volume: 274, Issue:1-3

    Topics: Analysis of Variance; Animals; Avoidance Learning; Behavior, Animal; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Depression; Desipramine; Dihydroxyphenylalanine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Levodopa; Male; Motor Activity; Nitriles; Nitrophenols; Rats; Rats, Wistar; Swimming; Tolcapone

1995
Effect of catechol-O-methyl transferase inhibition on peripheral and central metabolism of 6-[18F]fluoro-L-dopa.
    European journal of pharmacology, 1994, May-12, Volume: 257, Issue:1-2

    Topics: Animals; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Cerebellum; Chromatography, High Pressure Liquid; Corpus Striatum; Dihydroxyphenylalanine; Fluorine Radioisotopes; Male; Nitriles; Rats; Rats, Wistar

1994
Absence of 6-hydroxydopamine in the rat brain after treatment with stimulants and other dopaminergic agents: a mass fragmentographic study.
    Journal of neurochemistry, 1993, Volume: 61, Issue:4

    Topics: Animals; Brain; Carbidopa; Corpus Striatum; Dihydroxyphenylalanine; Dopamine Agents; Drug Combinations; Drug Stability; Frontal Lobe; Gas Chromatography-Mass Spectrometry; Injections, Intraventricular; Male; Oxidopamine; Pargyline; Rats; Rats, Sprague-Dawley; Stimulation, Chemical

1993
Evaluation of the ratio method compared with graphical analyses for estimating nigrostriatal function in human 18F-dopa PET studies with or without carbidopa.
    Nuclear medicine communications, 1993, Volume: 14, Issue:10

    Topics: Adult; Carbidopa; Corpus Striatum; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Male; Middle Aged; Parkinson Disease; Reference Values; Substantia Nigra; Tomography, Emission-Computed

1993
Pharmacokinetics of plasma 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine ([18F]Fdopa) in humans.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1993, Volume: 13, Issue:4

    Topics: Adult; Arteries; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Fluorine Radioisotopes; Humans; Parkinson Disease; Reference Values; Tomography, Emission-Computed

1993
Suppression of dyskinesias in advanced Parkinson's disease. I. Continuous intravenous levodopa shifts dose response for production of dyskinesias but not for relief of parkinsonism in patients with advanced Parkinson's disease.
    Neurology, 1993, Volume: 43, Issue:8

    Topics: Aged; Antiparkinson Agents; Carbidopa; Dihydroxyphenylalanine; Dose-Response Relationship, Drug; Drug Combinations; Female; Humans; Infusions, Intravenous; Levodopa; Male; Middle Aged; Movement Disorders; Parkinson Disease; Tyrosine

1993
Effects of catechol-O-methyltransferase inhibitors and L-3,4-dihydroxyphenylalanine with or without carbidopa on extracellular dopamine in rat striatum.
    Journal of neurochemistry, 1993, Volume: 60, Issue:1

    Topics: Animals; Benzophenones; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Extracellular Space; Male; Nitriles; Nitrophenols; Rats; Rats, Sprague-Dawley; Tolcapone; Tyrosine

1993
Synthesis and evaluation of an 18F-labeled dopa prodrug as a PET tracer for studying brain dopamine metabolism.
    Nuclear medicine and biology, 1996, Volume: 23, Issue:3

    Topics: Animals; Benzophenones; Biotransformation; Brain; Carbidopa; Catechol O-Methyltransferase Inhibitors; Cerebral Cortex; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Enzyme Inhibitors; Fluorine Radioisotopes; Injections, Intravenous; Mice; Nitrophenols; Prodrugs; Time Factors; Tissue Distribution; Tolcapone; Tomography, Emission-Computed

1996
The potential of high-resolution positron emission tomography to monitor striatal dopaminergic function in rat models of disease.
    Journal of neuroscience methods, 1996, Volume: 67, Issue:2

    Topics: Animals; Carbidopa; Carbon Isotopes; Carrier Proteins; Cerebellum; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Huntington Disease; Male; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Parkinson Disease, Secondary; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Receptors, Dopamine D2; Tomography, Emission-Computed

1996
Flow injection spectrophotometric determination of L-Dopa and carbidopa in pharmaceutical formulations using a crude extract of sweet potato root [Ipomoea batatas (L.) Lam.] as enzymatic source.
    The Analyst, 1997, Volume: 122, Issue:4

    Topics: Carbidopa; Dihydroxyphenylalanine; Levodopa; Spectrophotometry; Technology, Pharmaceutical; Vegetables

1997
In vivo regulation of DOPA decarboxylase by dopamine receptors in rat brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1997, Volume: 17, Issue:11

    Topics: Animals; Apomorphine; Brain; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine Agents; Dopamine Agonists; Dopamine Antagonists; Flupenthixol; Kinetics; Male; Rats; Rats, Wistar; Receptors, Dopamine

1997
Fluorine-18-fluoro-L-DOPA dosimetry with carbidopa pretreatment.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:11

    Topics: Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Dihydroxyphenylalanine; Enzyme Inhibitors; Fluorine Radioisotopes; Humans; Premedication; Radiation Dosage; Radiation Protection; Tissue Distribution; Tomography, Emission-Computed; Urinary Bladder

1998
Cerebral 6-[(18)F]fluoro-L-DOPA (FDOPA) metabolism in pig studied by positron emission tomography.
    Synapse (New York, N.Y.), 1999, Sep-15, Volume: 33, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Aromatic Amino Acid Decarboxylase Inhibitors; Blood-Brain Barrier; Brain; Carbidopa; Dihydroxyphenylalanine; Female; Fluorine Radioisotopes; Humans; Kinetics; Macaca fascicularis; Metabolic Clearance Rate; Models, Neurological; Rats; Swine; Tomography, Emission-Computed

1999
Striatal D2 dopamine receptor status in Parkinson's disease: an [18F]dopa and [11C]raclopride PET study.
    Movement disorders : official journal of the Movement Disorder Society, 1999, Volume: 14, Issue:6

    Topics: Adult; Aged; Antiparkinson Agents; Brain Mapping; Carbidopa; Carbon Radioisotopes; Corpus Striatum; Dihydroxyphenylalanine; Drug Combinations; Female; Fluorine Radioisotopes; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Raclopride; Receptors, Dopamine D2; Tomography, Emission-Computed

1999
Enantioseparation of 3,4-dihydroxyphenylalanine and 2-hydrazino-2-methyl-3-(3,4-dihydroxyphenyl)propanoic acid by capillary electrophoresis using cyclodextrins.
    Journal of chromatography. A, 2000, Apr-14, Volume: 875, Issue:1-2

    Topics: Carbidopa; Cyclodextrins; Dihydroxyphenylalanine; Electrophoresis, Capillary; Stereoisomerism

2000
Enantiomeric separation of dihydroxyphenylalanine (DOPA), methyldihydroxyphenylalanine (MDOPA) and hydrazinomethyldihydroxyphenylalanine (CDOPA) by using capillary electrophoresis with sulfobutyl ether-beta-cyclodextrin as a chiral selector.
    Electrophoresis, 2000, Volume: 21, Issue:15

    Topics: beta-Cyclodextrins; Carbidopa; Cyclodextrins; Dihydroxyphenylalanine; Electrophoresis, Capillary; Indicators and Reagents; Methyldopa; Stereoisomerism

2000
Dopaminergic denervation enhances susceptibility to hydroxyl radicals in rat neostriatum.
    Amino acids, 2000, Volume: 19, Issue:1

    Topics: Animals; Carbidopa; Chromatography, High Pressure Liquid; Denervation; Dihydroxyphenylalanine; Dopamine; Female; Gentisates; Hydroxybenzoates; Hydroxyl Radical; Neostriatum; Pregnancy; Rats; Salicylic Acid; Serotonin

2000
Simultaneous determination of dopa and carbidopa enantiomers by capillary zone electrophoresis.
    Electrophoresis, 2002, Volume: 23, Issue:19

    Topics: Carbidopa; Cyclodextrins; Dihydroxyphenylalanine; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Reproducibility of Results; Sensitivity and Specificity; Stereoisomerism

2002
D-dopa is unidirectionally converted to L-dopa by D-amino acid oxidase, followed by dopa transaminase.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:11

    Topics: Animals; Carbidopa; D-Amino-Acid Oxidase; Dihydroxyphenylalanine; Enzyme Inhibitors; Kidney; Levodopa; Mice; Rats; Rats, Sprague-Dawley; Sodium Benzoate

2006
Premedication with carbidopa masks positive finding of insulinoma and beta-cell hyperplasia in [(18)F]-dihydroxy-phenyl-alanine positron emission tomography.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Nov-10, Volume: 26, Issue:32

    Topics: Carbidopa; Diagnostic Errors; Dihydroxyphenylalanine; Enzyme Inhibitors; Fluorine Radioisotopes; Humans; Hyperplasia; Insulin-Secreting Cells; Insulinoma; Male; Middle Aged; Pancreatic Neoplasms; Positron-Emission Tomography; Predictive Value of Tests; Premedication; Radiopharmaceuticals

2008
Oxidation of carbidopa by tyrosinase and its effect on murine melanoma.
    Bioorganic & medicinal chemistry letters, 2009, Jul-01, Volume: 19, Issue:13

    Topics: Animals; Antineoplastic Agents; Carbidopa; Cell Line, Tumor; Cyclization; Dihydroxyphenylalanine; Melanoma; Mice; Monophenol Monooxygenase; Oxidation-Reduction; Prodrugs

2009
Peripheral COMT inhibition prevents levodopa associated homocysteine increase.
    Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Antiparkinson Agents; Carbidopa; Catechol O-Methyltransferase Inhibitors; Catechols; Delayed-Action Preparations; Dihydroxyphenylalanine; Enzyme Inhibitors; Female; Homocysteine; Humans; Levodopa; Male; Middle Aged; Nitriles; Parkinson Disease; Time Factors; Tyrosine

2009
A longitudinal study of motor performance and striatal [18F]fluorodopa uptake in Parkinson's disease.
    Brain imaging and behavior, 2011, Volume: 5, Issue:3

    Topics: Aged; Aging; Antiparkinson Agents; Carbidopa; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Female; Hand Strength; Humans; Isometric Contraction; Levodopa; Longitudinal Studies; Male; Middle Aged; Muscle Strength; Neuropsychological Tests; Parkinson Disease; Positron-Emission Tomography; Psychomotor Performance; Radiopharmaceuticals; Reaction Time; Retrospective Studies; Sex Characteristics; Tongue

2011
Beneficial effects of natural phenolics on levodopa methylation and oxidative neurodegeneration.
    Brain research, 2013, Feb-25, Volume: 1497

    Topics: Adrenergic Uptake Inhibitors; Analysis of Variance; Animals; Antiparkinson Agents; Carbidopa; Catechin; Catechol O-Methyltransferase; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Disease Models, Animal; Excitatory Amino Acid Agonists; Fluoresceins; Glial Fibrillary Acidic Protein; Hippocampus; Hydroxybenzoates; In Vitro Techniques; Kainic Acid; Levodopa; Male; Methylation; Mice; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Reserpine; Time Factors; Tyrosine

2013
Solid pseudopapillary pancreatic tumor mimicking a neuroendocrine neoplasm on ¹⁸F-FDOPA PET/CT.
    The Journal of clinical endocrinology and metabolism, 2013, Volume: 98, Issue:7

    Topics: Adult; Carbidopa; Diagnosis, Differential; Dihydroxyphenylalanine; Dopamine Agents; Fluorine Radioisotopes; Humans; Male; Multimodal Imaging; Neuroendocrine Tumors; Pancreas; Pancreatic Neoplasms; Positron-Emission Tomography; Premedication; Radiopharmaceuticals; Tomography, X-Ray Computed

2013
18F-FDOPA PET/CT imaging of insulinoma revisited.
    European journal of nuclear medicine and molecular imaging, 2015, Volume: 42, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Carbidopa; Dihydroxyphenylalanine; Female; Humans; Hyperinsulinism; Insulinoma; Male; Middle Aged; Multimodal Imaging; Pancreatic Neoplasms; Positron-Emission Tomography; Premedication; Radiopharmaceuticals; Tomography, X-Ray Computed

2015
Dynamic 18F-FDOPA PET Findings After Carbidopa Premedication in 2 Adult Patients With Insulinoma-Related Hyperinsulinemic Hypoglycemia.
    Clinical nuclear medicine, 2015, Volume: 40, Issue:8

    Topics: Adult; Carbidopa; Dihydroxyphenylalanine; Female; Humans; Hyperinsulinism; Hypoglycemia; Insulinoma; Male; Middle Aged; Multimodal Imaging; Pancreatic Neoplasms; Positron-Emission Tomography; Premedication; Radiopharmaceuticals; Tomography, X-Ray Computed

2015
Simultaneous determination of levodopa, carbidopa, entacapone, tolcapone, 3-O-methyldopa and dopamine in human plasma by an HPLC-MS/MS method.
    Bioanalysis, 2015, Volume: 7, Issue:2

    Topics: Benzophenones; Blood Chemical Analysis; Carbidopa; Catechols; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Dopamine; Humans; Levodopa; Nitriles; Nitrophenols; Quality Control; Reproducibility of Results; Tandem Mass Spectrometry; Tolcapone; Tyrosine

2015
Evaluation of 6-11C-Methyl-m-Tyrosine as a PET Probe for Presynaptic Dopaminergic Activity: A Comparison PET Study with β-11C-l-DOPA and 18F-FDOPA in Parkinson Disease Monkeys.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2016, Volume: 57, Issue:2

    Topics: Animals; Brain; Carbidopa; Dihydroxyphenylalanine; Dopamine Plasma Membrane Transport Proteins; Dopaminergic Neurons; Enzyme Inhibitors; Levodopa; Macaca fascicularis; MPTP Poisoning; Parkinson Disease, Secondary; Positron-Emission Tomography; Radiopharmaceuticals; Receptors, Presynaptic; Tyrosine

2016
Simultaneous estimation of levodopa, carbidopa and 3-oxymethyldopa in rat plasma using HPLC-ECD.
    Biomedical chromatography : BMC, 2016, Volume: 30, Issue:10

    Topics: Animals; Carbidopa; Chromatography, High Pressure Liquid; Dihydroxyphenylalanine; Electrochemical Techniques; Levodopa; Limit of Detection; Male; Rats; Rats, Wistar; Tyrosine

2016
Effect of Carbidopa on 18F-FDOPA Uptake in Insulinoma: From Cell Culture to Small-Animal PET Imaging.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017, Volume: 58, Issue:1

    Topics: Animals; Carbidopa; Cell Line, Tumor; Dihydroxyphenylalanine; Female; Image Enhancement; Insulinoma; Metabolic Clearance Rate; Mice, Nude; Organ Specificity; Pancreatic Neoplasms; Positron-Emission Tomography; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tissue Distribution

2017
Pancreatic Uptake by 18F-FDOPA PET/CT in Patients With Hypoglycemia After Gastric Bypass Surgery Compared With Controls With or Without Carbidopa Pretreatment.
    Clinical nuclear medicine, 2017, Volume: 42, Issue:3

    Topics: Adult; Aged; Carbidopa; Case-Control Studies; Dihydroxyphenylalanine; Dopamine Agents; Female; Fluorine Radioisotopes; Gastric Bypass; Humans; Hypoglycemia; Male; Middle Aged; Pancreas; Pancreatic Diseases; Positron Emission Tomography Computed Tomography; Positron-Emission Tomography; Premedication; Radiopharmaceuticals; Retrospective Studies

2017
Clinical Value of
    Anticancer research, 2018, Volume: 38, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Dihydroxyphenylalanine; Female; Humans; Insulinoma; Male; Middle Aged; Positron Emission Tomography Computed Tomography; Premedication; Radiopharmaceuticals; Retrospective Studies

2018