carbene has been researched along with largazole in 1 studies
| Studies (carbene) | Trials (carbene) | Recent Studies (post-2010) (carbene) | Studies (largazole) | Trials (largazole) | Recent Studies (post-2010) (largazole) |
|---|---|---|---|---|---|
| 2,067 | 0 | 1,265 | 67 | 0 | 50 |
| Protein | Taxonomy | carbene (IC50) | largazole (IC50) |
|---|---|---|---|
| Histone deacetylase 3 | Homo sapiens (human) | 0.7249 | |
| Cytochrome P450 2D6 | Homo sapiens (human) | 0.34 | |
| Histone deacetylase 4 | Homo sapiens (human) | 3 | |
| Histone deacetylase 1 | Homo sapiens (human) | 0.3111 | |
| Histone deacetylase 2 | Homo sapiens (human) | 0.8721 | |
| Polyamine deacetylase HDAC10 | Homo sapiens (human) | 2.21 | |
| Histone deacetylase 8 | Homo sapiens (human) | 0.594 | |
| Histone deacetylase 6 | Homo sapiens (human) | 2.6091 | |
| Histone deacetylase 9 | Homo sapiens (human) | 8.33 | |
| Nuclear receptor corepressor 2 | Homo sapiens (human) | 2.002 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, CS; Forsyth, CJ; Huang, PH; Wang, B | 1 |
1 other study(ies) available for carbene and largazole
| Article | Year |
|---|---|
Total syntheses of the histone deacetylase inhibitors largazole and 2-epi-largazole: application of N-heterocyclic carbene mediated acylations in complex molecule synthesis.
Topics: Acylation; Biological Products; Cell Line, Tumor; Cell Survival; Depsipeptides; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Heterocyclic Compounds; Histone Deacetylase Inhibitors; Humans; Male; Methane; Stereoisomerism; Structure-Activity Relationship; Thiazoles | 2011 |