Page last updated: 2024-09-03

carbene and isatin

carbene has been researched along with isatin in 12 studies

Compound Research Comparison

Studies
(carbene)
Trials
(carbene)
Recent Studies (post-2010)
(carbene)
Studies
(isatin)
Trials
(isatin)
Recent Studies (post-2010) (isatin)
2,06701,2651,0933575

Protein Interaction Comparison

ProteinTaxonomycarbene (IC50)isatin (IC50)
Amine oxidase [flavin-containing] AHomo sapiens (human)8.43
Amine oxidase [flavin-containing] BHomo sapiens (human)5.2478
Secreted chorismate mutaseMycobacterium tuberculosis H37Rv1.08

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (8.33)29.6817
2010's10 (83.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Mohan, R; Nair, V; Poonoth, M; Suresh, E; Vellalath, S1
Hayashi, T; Shintani, R; Takatsu, K1
Chi, YR; Lv, H; Mo, J; Tiwari, B; Xing, C1
Jiao, W; Li, T; Liu, R; Xiao, Z; Yao, C; Yu, C1
Li, T; Liu, R; Wang, X; Xiao, Z; Xie, Y; Yao, C; Yu, C1
Du, D; Lu, T; Lu, Y; Tang, W; Zhang, Y1
Chi, YR; Mou, C; Song, BA; Xu, J; Zhu, T1
Li, T; Que, Y; Wang, XS; Yao, C; Yu, C1
Li, T; Lu, Y; Wang, W; Wang, Y; Yao, C; Yu, C; Zhu, L1
Du, Y; Liu, H; Rong, X; Xia, W; Yao, H; Zhou, Y1
Aldilla, V; Bhadbhade, M; Black, DS; Kumar, N; Suryanti, V; Zhang, R1
Gong, LZ; Song, J; Wen, YH; Zhang, ZJ1

Other Studies

12 other study(ies) available for carbene and isatin

ArticleYear
N-heterocyclic carbene catalyzed reaction of enals and 1,2-dicarbonyl compounds: stereoselective synthesis of spiro gamma-butyrolactones.
    Organic letters, 2006, Feb-02, Volume: 8, Issue:3

    Topics: 4-Butyrolactone; Aldehydes; Catalysis; Hydrocarbons; Isatin; Methane; Molecular Structure; Spiro Compounds; Stereoisomerism

2006
Copper-catalyzed asymmetric addition of arylboronates to isatins: a catalytic cycle involving alkoxocopper intermediates.
    Chemical communications (Cambridge, England), 2010, Sep-28, Volume: 46, Issue:36

    Topics: Boronic Acids; Catalysis; Copper; Crystallography, X-Ray; Indoles; Isatin; Ligands; Methane; Molecular Conformation; Oxindoles; Stereoisomerism

2010
Highly enantioselective addition of enals to isatin-derived ketimines catalyzed by N-heterocyclic carbenes: synthesis of spirocyclic γ-lactams.
    Organic letters, 2012, Nov-02, Volume: 14, Issue:21

    Topics: Aldehydes; Catalysis; Imines; Indoles; Isatin; Lactams; Methane; Molecular Structure; Nitriles; Oxindoles; Spiro Compounds; Stereoisomerism

2012
N-Heterocyclic-carbene-catalyzed reaction of α-bromo-α,β-unsaturated aldehyde or α,β-dibromoaldehyde with isatins: an efficient synthesis of spirocyclic oxindole-dihydropyranones.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2013, Jan-07, Volume: 19, Issue:2

    Topics: Aldehydes; Catalysis; Chemistry Techniques, Synthetic; Halogenation; Indoles; Isatin; Methane; Oxindoles; Spiro Compounds

2013
NHC-catalyzed oxidative γ-addition of α,β-unsaturated aldehydes to isatins: a high-efficiency synthesis of spirocyclic oxindole-dihydropyranones.
    Organic & biomolecular chemistry, 2014, Mar-28, Volume: 12, Issue:12

    Topics: Aldehydes; Catalysis; Heterocyclic Compounds; Indoles; Isatin; Methane; Molecular Structure; Oxidation-Reduction; Oxindoles; Pyrones; Spiro Compounds

2014
Cooperative N-heterocyclic carbene (NHC)-Lewis acid-mediated regioselective umpolung formal [3 + 2] annulations of alkynyl aldehydes with isatins.
    Organic & biomolecular chemistry, 2014, May-21, Volume: 12, Issue:19

    Topics: Acids, Heterocyclic; Aldehydes; Alkynes; Catalysis; Chemistry, Organic; Crystallography, X-Ray; Isatin; Lewis Acids; Methane; Stereoisomerism

2014
N-Heterocyclic carbene-catalyzed chemoselective cross-aza-benzoin reaction of enals with isatin-derived ketimines: access to chiral quaternary aminooxindoles.
    Organic letters, 2014, Jun-20, Volume: 16, Issue:12

    Topics: Aza Compounds; Benzoin; Catalysis; Imines; Indoles; Isatin; Methane; Molecular Structure; Nitriles; Stereoisomerism

2014
Enantioselective assembly of spirocyclic oxindole-dihydropyranones through NHC-catalyzed cascade reaction of isatins with N-hydroxybenzotriazole esters of α,β-unsaturated carboxylic acid.
    The Journal of organic chemistry, 2015, Mar-20, Volume: 80, Issue:6

    Topics: Carboxylic Acids; Catalysis; Esters; Heterocyclic Compounds; Indoles; Isatin; Methane; Molecular Structure; Pyrones; Spiro Compounds; Stereoisomerism; Triazoles

2015
N-Heterocyclic carbene-catalyzed [4 + 2] cyclization of α,β-unsaturated carboxylic acids bearing γ-H with isatins: an enantioselective synthesis of spirocyclic oxindole-dihydropyranones.
    Organic & biomolecular chemistry, 2016, Jan-28, Volume: 14, Issue:4

    Topics: Carboxylic Acids; Catalysis; Crystallography, X-Ray; Cyclization; Heterocyclic Compounds; Indoles; Isatin; Methane; Models, Molecular; Molecular Structure; Spiro Compounds; Stereoisomerism

2016
Enantioselective Assembly of Spirolactones through NHC-Catalyzed Remote γ-Carbon Addition of Enals with Isatins.
    ACS combinatorial science, 2016, 05-09, Volume: 18, Issue:5

    Topics: Aldehydes; Catalysis; Isatin; Methane; Spironolactone; Stereoisomerism

2016
Synthesis of Bis-Glyoxylamide Peptidomimetics Derived from Bis-
    Molecules (Basel, Switzerland), 2019, Nov-27, Volume: 24, Issue:23

    Topics: Alcohols; Amines; Amino Acids; Esters; Indoles; Isatin; Methane; Models, Molecular; Molecular Structure; Oxygen; Peptidomimetics; X-Rays

2019
Kinetic Resolution of Aziridines Enabled by N-Heterocyclic Carbene/Copper Cooperative Catalysis: Carbene Dose-Controlled Chemo-Switchability.
    Angewandte Chemie (International ed. in English), 2021, 02-08, Volume: 60, Issue:6

    Topics: Aziridines; Catalysis; Copper; Cycloaddition Reaction; Heterocyclic Compounds; Isatin; Kinetics; Methane; Oxindoles; Spiro Compounds; Stereoisomerism

2021