carbapenems has been researched along with valproic acid glucuronide in 5 studies
| Studies (carbapenems) | Trials (carbapenems) | Recent Studies (post-2010) (carbapenems) | Studies (valproic acid glucuronide) | Trials (valproic acid glucuronide) | Recent Studies (post-2010) (valproic acid glucuronide) |
|---|---|---|---|---|---|
| 7,355 | 147 | 5,277 | 30 | 1 | 9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mizutani, T; Mori, H; Takahashi, K | 1 |
| Mizutani, T; Nakahira, K; Nakamura, Y | 1 |
| Hisaka, A; Honma, M; Ito, K; Masuo, Y; Suzuki, H; Yamamoto, T | 1 |
| Fusegawa, K; Goda, R; Ikenaga, H; Izumi, T; Kobayashi, N; Kuga, H; Nakai, D; Suzuki, E | 1 |
| Higuchi, N; Ishikawa, T; Kuriyama, M; Mizuta, S; Nakashima, M; Nakashima, MN; Ohyama, K; Onomura, O; Otaki, H | 1 |
1 review(s) available for carbapenems and valproic acid glucuronide
| Article | Year |
|---|---|
Interaction between valproic acid and carbapenem antibiotics.
Topics: Animals; Anti-Bacterial Agents; Anticonvulsants; Carbapenems; Carrier Proteins; Drug Interactions; Enzyme Activation; Enzyme Activators; Enzyme Inhibitors; Erythrocytes; Glucuronidase; Glucuronosyltransferase; Humans; Intestinal Absorption; Intestines; Kidney; Liver; Rats; Uridine Diphosphate Glucuronic Acid; Valproic Acid | 2007 |
4 other study(ies) available for carbapenems and valproic acid glucuronide
| Article | Year |
|---|---|
Decreased valproate level caused by VPA-glucuronidase inhibition by carbapenem antibiotics.
Topics: Anti-Bacterial Agents; Anticonvulsants; Carbapenems; Cytosol; Drug Interactions; Enzyme Inhibitors; Glucuronidase; Humans; Hydrolysis; Liver; Microsomes, Liver; Valproic Acid | 2008 |
Characterization of inhibitory effect of carbapenem antibiotics on the deconjugation of valproic acid glucuronide.
Topics: Animals; Carbapenems; Cytosol; Dose-Response Relationship, Drug; Drug Interactions; Glucuronidase; Humans; In Vitro Techniques; Kinetics; Liver; Male; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Substrate Specificity; Tandem Mass Spectrometry; Valproic Acid | 2010 |
In vivo inhibition of acylpeptide hydrolase by carbapenem antibiotics causes the decrease of plasma concentration of valproic acid in dogs.
Topics: Administration, Intravenous; Animals; Carbapenems; Cytosol; Dogs; Drug Interactions; Enzyme Inhibitors; Hydrolysis; Kidney; Liver; Male; Meropenem; Peptide Hydrolases; Protease Inhibitors; Thienamycins; Valproic Acid | 2016 |
Computational study of the competitive binding of valproic acid glucuronide and carbapenem antibiotics to acylpeptide hydrolase.
Topics: Binding, Competitive; Carbapenems; Humans; Models, Molecular; Molecular Structure; Peptide Hydrolases; Valproic Acid | 2017 |