Compounds > carbapenems
Page last updated: 2024-09-04

carbapenems and sulbactam

carbapenems has been researched along with sulbactam in 73 studies

Compound Research Comparison

Studies
(carbapenems)		Trials
(carbapenems)		Recent Studies (post-2010)
(carbapenems)		Studies
(sulbactam)		Trials
(sulbactam)		Recent Studies (post-2010) (sulbactam)
7,3551475,2771,844297488

Protein Interaction Comparison

ProteinTaxonomycarbapenems (IC50)sulbactam (IC50)
Beta-lactamase Escherichia coli6.2
Beta-lactamase Shouchella clausii0.075
Beta-lactamase Pseudomonas aeruginosa0.37
Beta-lactamase Pseudomonas aeruginosa3
Beta-lactamase Aeromonas allosaccharophila4
Beta-lactamaseStaphylococcus aureus6.5
Beta-lactamaseEnterobacter cloacae1.4
Beta-lactamase TEMEscherichia coli4.3
Beta-lactamase Acinetobacter pittii1.12
Beta-lactamase Acinetobacter pittii7.758
Beta-lactamase Pseudomonas aeruginosa3
Beta-lactamase Escherichia coli2.4

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.37)18.7374
1990's1 (1.37)18.2507
2000's10 (13.70)29.6817
2010's43 (58.90)24.3611
2020's18 (24.66)2.80

Authors

AuthorsStudies
Inouye, S; Ito, T; Kazuno, Y; Kojima, M; Niwa, T; Tamura, A; Yoshida, T1
Hashizume, T; Hazumi, N; Kato, Y; Matsuda, K1
Powell, LL; Wilson, SE1
Chai, D; Li, Z; Pei, F; Tong, W; Wang, R1
Chang, CY; Chang, YL; Hsu, CK; Hsueh, PR; Kuo, LC; Lai, CC; Liao, CH1
Cassone, A; Di Sora, F; Dionisi, AM; Gallo, S; Longo, B; Luzzi, I; Monaco, M; Montella, F; Pantosti, A; Placanica, P; Rezza, G; Tarasi, A; Volpe, I1
Cheong, HJ; Hwang, IS; Jeong, HW; Kee, SY; Kim, WJ; Seo, YB; Song, JY1
Durante-Mangoni, E; Fortunato, R; Tripodi, MF; Utili, R; Zarrilli, R1
Correia, A; Domingues, MR; Domingues, P; Fonseca, F; Henriques, I; Saavedra, MJ; Samyn, B; Sarmento, AC; van Beeumen, J1
Cherkashin, EA; Galeeva, EV; Ivanov, DV; Krapivina, IV; Sidorenko, SV; Veshutova, NS1
Kuti, JL; Nicasio, AM; Nicolau, DP1
Costa, SF; Grinbaum, RS; Levin, AS; Oliveira, MS; Prado, GV1
Amornnopparattanakul, S; Dhiraputra, C; Fungwithaya, S; Leelarasamee, A; Nannha, P; Panapakdee, S; Pongpech, P1
Otük, G; Ozbek, B1
dos Santos, RP; Goldani, LZ; Jacoby, T1
Akyüz, C; Büyükpamukçu, M; Cengiz, B; Ceyhan, M; Demir, HA; Kara, A; Kutluk, T; Seçmeer, G; Varan, A; Yağcı-Küpeli, B; Yalçın, B1
Bethel, CR; Bonnet, R; Bonomo, RA; Distler, AM; Endimiani, A; Hujer, AM; Hujer, KM; Papp-Wallace, K; Shyr, T; Taracila, M; Thomson, JM1
Antunes, NT; Frase, H; Toth, M; Vakulenko, SB; Vakulenko, V1
Hagihara, M; Housman, ST; Kuti, JL; Nicolau, DP1
Costa, SF; Levin, AS; Oliveira, MS; Pedri, Ed; van der Heijden, I1
Hiraki, Y; Inoue, D; Kamimura, H; Karube, Y; Kawano, F; Masuda, Y; Takaki, K; Tsuji, Y; Yoshida, M1
Bao, Y; Cai, Y; Chai, T; Gao, J; Li, X; Ma, R; Zhao, X; Zhou, Y1
Ahmed, H; Awali, RA; Chaudary, K; Chopra, T; Hothi, J; Johnson, P; Kaye, KS; Krishna, A; Lephart, P; Marchaim, D; Pogue, JM; Slim, J; Tansek, R; Zhao, JJ1
Clancy, CJ; Doi, Y; Nguyen, MH; O'Hara, JA; Oleksiuk, LM; Press, EG; Shields, RK; Updike, CL1
Bosnak, VK; Karaoglan, I; Mete, AO; Namiduru, M; Zer, Y1
Ahmed, SS; Alp, E; Demiraslan, H; Dinc, G; Doganay, M; Elmali, F; Metan, G1
Agalar, C; Akalin, S; Alici, O; Alp, E; Altay, FA; Altin, N; Arslan, F; Aslan, T; Balkan, II; Batirel, A; Bekiroglu, N; Celik, AD; Cesur, S; Dogan, M; Durdu, B; Duygu, F; Engin, A; Engin, DO; Gonen, I; Guclu, E; Guven, T; Hatipoglu, CA; Hosoglu, S; Karabay, O; Karahocagil, MK; Kilic, AU; Ormen, B; Ozdemir, D; Ozer, S; Oztoprak, N; Sezak, N; Turhan, V; Turker, N; Yilmaz, H1
Apisarnthanarak, A; Khawcharoenporn, T; Mundy, LM; Pruetpongpun, N; Rutchanawech, S; Tiamsak, P1
Fang, X; Gong, M; Xia, J; Xu, Y; Zhang, D; Zhou, Y1
Aleksandrova, IV; Borisova, LA; Chernen'kaia, TV; Kosolapov, DA; Nikitina, OV; Reĭ, SI1
Arslan, U; Kus, H; Tuncer, I; Turk Dagi, H1
Wu, H; Xie, W; Ye, Z; Zhang, W; Zhao, C1
Alp, E; Cevahir, F; Kaynar, L; Metan, G; Pala, Ç1
Doi, Y; Ernst, RK; Hittle, LE; O'Hara, JA; Pasculle, AW; Qureshi, ZA; Rivera, JI; Shields, RK; Syed, A1
Ahmed, SS; Alp, E; Demiraslan, H; Dinc, G; Doganay, M; Elmali, F1
Cheng, CW; Hsu, PC; Huang, CT; Lee, MH; Leu, HS; Lin, HS; Ye, JJ1
Amaya-Villar, R; Díaz-Martín, A; Ferrándiz-Millón, C; Garnacho-Montero, J; Gutiérrez-Pizarraya, A; López-Sánchez, JM1
Acikgoz, ZC; Guner, R; Guven, T; Izdes, S; Kocak Tufan, Z; Tasyaran, MA; Yilmaz, GR1
Kollef, MH; Shorr, AF; Zilberberg, MD1
Barišić, Z; Goic-Barisic, I; Hrenović, J; Kaliterna, M; Kaliterna, V; Tonkić, M1
Dinghong, M; Fei, G; Guanghua, G; Guohui, L; Jianhua, Z; Nianyun, W; Xili, Y; Yue, L1
Beceiro, A; Bethel, CR; Bonomo, RA; Bou, G; Buynak, JD; González-Bello, C; Martínez-Guitián, M; Poza, M; Vallejo, JA; Vázquez-Ucha, JC1
Chang, FY; Chen, TL; Chiu, CH; Chuang, MF; Kuo, SC; Lee, YT; Lin, JC; Wang, YC; Yang, YS1
Fujiya, Y; Hayakawa, K; Kutsuna, S; Mawatari, M; Mezaki, K; Nagamatsu, M; Ohmagari, N; Takeshita, N; Tamura, S; Yamamoto, K1
Anandan, S; Balaji, V; Bhuvaneshwari, T; Devi, BY; Elakkiya, M; Laishram, S; Peter, JV; Priyanka, B; Subramani, K1
Huang, CT; Huang, PY; Lee, MH; Lin, HS; Wu, YM; Yang, CC; Ye, JJ; Yeh, CF1
Altunçekiç Yıldırım, A; Çalgın, MK; Çetinkol, Y; Telli, M1
Adibhesami, H; Aliramezani, A; Boroumand, MA; Douraghi, M; Ghourchian, S; Jasemi, S; Mohammadzadeh, M; Rahbar, M; Zeraati, H1
Li, P; Wang, W; Wang, X; Zhao, X1
Andrews, B; Bifulco, N; Carter, NM; Chen, B; Comita-Prevoir, J; de Jonge, B; Durand-Réville, TF; Ehmann, DE; Gao, N; Giacobbe, RA; Guler, S; Huynh, H; Lahiri, S; McLaughlin, R; McLeod, SM; Miller, AA; Moussa, SH; Mueller, JP; Newman, JV; O'Donnell, J; Olivier, NB; Palmer, T; Shapiro, AB; Thresher, J; Tommasi, RA; Velez-Vega, C1
Cao, J; Hu, Y; Huang, JJ; Jin, Z; Que, CL; Wang, GF; Wang, X; Zhang, H; Zhang, W1
Cai, Y; Wang, J; Wang, R; Yang, D1
Guo, Q; Hu, F; Li, Y; Su, J; Wang, M; Wu, S; Xu, S1
Abdollahi, A; Beigmohammadi, MT; Doomanlou, M; Khalili, H; Mohammadi, M; Shojaei, L1
Abdelgani, S; Amir-Ronen, R; Geffen, Y; Liron, Y; Ohanyan, A; Paul, M; Raz-Pasteur, A1
Babaie, Z; Delfani, S; Mahdian, S; Norolahi, F; Rezaei, F; Shakib, P1
Akinci, E; Baran, I; Bodur, H; Mumcuoglu, I; Sertcelik, A1
Li, X; Lu, C; Sun, S; Wang, D; Wang, Y1
Higgins, PG; Kresken, M; Miller, A; Müller, C; Seifert, H; Stefanik, D1
Ayfan, AK; Mohd Sazlly Lim, S; Naicker, S; Roberts, JA; Sime, FB; Zowawi, H1
Academia, EC; Jenrette, JE; McLaughlin, JM; Mueller, SW1
Bouvier, M; Findlay, J; Nordmann, P; Poirel, L1
Baez, M; Bonomo, RA; Cedano, J; Corso, A; Fua, V; Montaña, SD; Pasteran, F; Ra, G; Ramírez, MS; Tolmasky, ME1
Bellini, R; Ciapina, LP; Dardenne, LE; de Vasconcelos, ATR; Guedes, IA; Nicolás, MF1
Abu-Taleb, R; Alamneh, YA; Bushnell, RV; Czintos, CM; Daly, MJ; Dollery, SJ; Escatte, MG; MacLeod, DA; Meeks, HN; Su, W; Tasker, NJPER; Tobin, GJ; Tobin, JK; Wiggins, TJ; Zurawski, DV1
Chen, L; Deng, Y; Huang, X; Yang, Y; Yu, H; Yue, M1
Akcam, FZ; Cetin, ES; Gonen, I; Kaya, O; Ozturk, T; Temel, EN; Unal, O1
Bonomo, RA; Watkins, RR1
Paterson, DL; Shields, RK; Tamma, PD1
Altarac, D; Du, B; Isaacs, R; Watkins, RR1
Acman, M; Chiu, CH; Hamawandi, A; Lindsay, JA; Readman, JB; Sharland, M; Standing, JF1
Jiang, J; Liu, X; Long, Y; Qiao, L; Wang, Q; Wu, J; Xu, T; Yang, Y; Yu, J; Zhang, B; Zuo, W1
Liu, H; Yang, M; Yang, Z1

Reviews

4 review(s) available for carbapenems and sulbactam

ArticleYear
The role of beta-lactam antimicrobials as single agents in treatment of intra-abdominal infection.
    Surgical infections, 2000, Volume: 1, Issue:1

    Topics: Abdomen; Abdominal Abscess; Ampicillin; Anti-Bacterial Agents; Bacterial Infections; beta-Lactamase Inhibitors; Carbapenems; Cephalosporins; Clavulanic Acids; Drug Resistance, Bacterial; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam; Surgical Wound Infection; Ticarcillin

2000
The current state of multidrug-resistant gram-negative bacilli in North America.
    Pharmacotherapy, 2008, Volume: 28, Issue:2

    Topics: Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Minocycline; North America; Polymyxins; Sulbactam; Tigecycline

2008
Optimum treatment strategies for carbapenem-resistant Acinetobacter baumannii bacteremia.
    Expert review of anti-infective therapy, 2015, Volume: 13, Issue:6

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacteremia; beta-Lactam Resistance; Carbapenems; Colistin; Drug Synergism; Drug Therapy, Combination; Fosfomycin; Humans; Microbial Sensitivity Tests; Minocycline; Polymyxins; Sulbactam; Tigecycline

2015
Navigating Available Treatment Options for Carbapenem-Resistant Acinetobacter baumannii-calcoaceticus Complex Infections.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 05-01, Volume: 76, Issue:Suppl 2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Carbapenems; Colistin; Humans; Microbial Sensitivity Tests; Sulbactam

2023

Trials

3 trial(s) available for carbapenems and sulbactam

ArticleYear
Comparison of sulbactam-cefoperazone with carbapenems as empirical monotherapy for febrile neutropenic children with lymphoma and solid tumors.
    Pediatric hematology and oncology, 2011, Volume: 28, Issue:4

    Topics: Adolescent; Carbapenems; Cefoperazone; Child; Child, Preschool; Female; Humans; Infant; Lymphoma; Male; Neutropenia; Sarcoma; Sulbactam

2011
Meropenem/colistin versus meropenem/ampicillin-sulbactam in the treatment of carbapenem-resistant pneumonia.
    Journal of comparative effectiveness research, 2018, Volume: 7, Issue:9

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Aged; Ampicillin; Anti-Bacterial Agents; Carbapenems; Colistin; Drug Combinations; Drug Resistance, Bacterial; Female; Humans; Male; Meropenem; Middle Aged; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Sulbactam

2018
Pathogen-Targeted Clinical Development to Address Unmet Medical Need: Design, Safety, and Efficacy of the ATTACK Trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 05-01, Volume: 76, Issue:Suppl 2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Sulbactam

2023

Other Studies

66 other study(ies) available for carbapenems and sulbactam

ArticleYear
In vitro evaluation of SF-2103A, a novel carbapenem antibiotic, as a beta-lactamase inhibitor.
    The Journal of antibiotics, 1986, Volume: 39, Issue:7

    Topics: Anti-Bacterial Agents; Bacteria; Bacteriolysis; beta-Lactamase Inhibitors; Carbapenems; Drug Synergism; Penicillanic Acid; Proteus vulgaris; Sulbactam

1986
Effects of a beta-lactamase inhibitor, sulbactam, on the activity of carbapenems against Pseudomonas aeruginosa.
    The Journal of antibiotics, 1995, Volume: 48, Issue:11

    Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Drug Synergism; Enzyme Inhibitors; Imipenem; Meropenem; Pseudomonas aeruginosa; Sulbactam; Thienamycins

1995
In vitro activity of cefepime combined with sulbactam against clinical isolates of carbapenem-resistant Acinetobacter spp.
    International journal of antimicrobial agents, 2006, Volume: 28, Issue:5

    Topics: Acinetobacter; Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Sulbactam

2006
Multidrug-resistant Acinetobacter baumannii bacteraemia: clinical features, antimicrobial therapy and outcome.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2007, Volume: 13, Issue:2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Amikacin; Ampicillin; Anti-Bacterial Agents; Bacteremia; Carbapenems; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Sulbactam; Treatment Outcome

2007
Molecular findings and antibiotic-resistance in an outbreak of Acinetobacter baumannii in an intensive care unit.
    Annali dell'Istituto superiore di sanita, 2007, Volume: 43, Issue:1

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Carbapenems; Colistin; Cross Infection; Disease Outbreaks; Disinfection; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Humans; Intensive Care Units; Male; Middle Aged; Patient Isolation; Rifampin; Rome; Sulbactam

2007
In vitro activities of carbapenem/sulbactam combination, colistin, colistin/rifampicin combination and tigecycline against carbapenem-resistant Acinetobacter baumannii.
    The Journal of antimicrobial chemotherapy, 2007, Volume: 60, Issue:2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Carbapenems; Colistin; Colony Count, Microbial; Drug Resistance, Bacterial; Humans; Microbial Sensitivity Tests; Minocycline; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; Sulbactam; Tigecycline

2007
Comparative activities of colistin, rifampicin, imipenem and sulbactam/ampicillin alone or in combination against epidemic multidrug-resistant Acinetobacter baumannii isolates producing OXA-58 carbapenemases.
    International journal of antimicrobial agents, 2007, Volume: 30, Issue:6

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Ampicillin; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Colistin; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Drug Synergism; Electrophoresis, Gel, Pulsed-Field; Humans; Imipenem; Italy; Microbial Sensitivity Tests; Rifampin; Sulbactam

2007
Biochemical Characterization of SFC-1, a class A carbapenem-hydrolyzing beta-lactamase.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:12

    Topics: Aztreonam; beta-Lactamases; Carbapenems; Catalysis; Cephalosporins; Clavulanic Acid; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Hydrolysis; Kinetics; Molecular Weight; Penicillanic Acid; Penicillins; Recombinant Proteins; Serratia; Sulbactam; Tazobactam

2007
[Resistance epidemiology of gramnegative nonfermenting pathogens of nosocomial infections in intensive care units and surgical departments].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2006, Volume: 51, Issue:7

    Topics: Acinetobacter baumannii; Adolescent; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefoperazone; Child; Child, Preschool; Cross Infection; Drug Resistance, Microbial; Genes, Bacterial; Gram-Negative Bacterial Infections; Humans; Infant; Intensive Care Units; Microbial Sensitivity Tests; Molecular Epidemiology; Moscow; Pseudomonas aeruginosa; Sulbactam; Surgery Department, Hospital

2006
Ampicillin/sulbactam compared with polymyxins for the treatment of infections caused by carbapenem-resistant Acinetobacter spp.
    The Journal of antimicrobial chemotherapy, 2008, Volume: 61, Issue:6

    Topics: Acinetobacter; Acinetobacter Infections; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Ampicillin; APACHE; beta-Lactam Resistance; Bronchoalveolar Lavage Fluid; Carbapenems; Child; Child, Preschool; Cross Infection; Female; Hospitals, Teaching; Humans; Infant; Logistic Models; Male; Middle Aged; Multivariate Analysis; Polymyxins; Prognosis; Renal Insufficiency; Retrospective Studies; Risk Factors; Shock, Septic; Sulbactam; Time Factors; Treatment Outcome

2008
Antibacterial activity of carbapenem-based combinations againts multidrug-resistant Acinetobacter baumannii.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2010, Volume: 93, Issue:2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Analysis of Variance; Anti-Bacterial Agents; Area Under Curve; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Imipenem; In Vitro Techniques; Meropenem; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Sulbactam; Thienamycins

2010
In vitro activities of tigecycline alone and in combination with colistin sulfate or sulbactam against carbapenem-susceptible and -resistant Acinetobacter baumannii strains isolated from Intensive Care Units.
    International journal of antimicrobial agents, 2010, Volume: 36, Issue:2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Carbapenems; Colistin; Cross Infection; Drug Resistance, Bacterial; Drug Synergism; Humans; Intensive Care Units; Meropenem; Microbial Sensitivity Tests; Minocycline; Sulbactam; Thienamycins; Tigecycline

2010
Antimicrobial stewardship lessons: do Pseudomonas-sparing agents, such as ertapenem, effectively improve bacterial resistance?
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:7

    Topics: Ampicillin; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Ertapenem; Humans; Imipenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Sulbactam

2010
Exploring the inhibition of CTX-M-9 by beta-lactamase inhibitors and carbapenems.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:7

    Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Clavulanic Acid; Enzyme Inhibitors; Escherichia coli Proteins; Kinetics; Meropenem; Molecular Dynamics Simulation; Molecular Structure; Penicillanic Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulbactam; Tazobactam; Thienamycins

2011
Class A carbapenemase FPH-1 from Francisella philomiragia.
    Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:6

    Topics: Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Clavulanic Acid; Doripenem; Ertapenem; Escherichia coli; Francisella; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Sulbactam; Tazobactam; Thienamycins

2012
In vitro pharmacodynamics of human-simulated exposures of ampicillin/sulbactam, doripenem and tigecycline alone and in combination against multidrug-resistant Acinetobacter baumannii.
    The Journal of antimicrobial chemotherapy, 2013, Volume: 68, Issue:10

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Ampicillin; Anti-Bacterial Agents; Bacterial Load; Carbapenems; Doripenem; Drug Combinations; Drug Resistance, Multiple, Bacterial; Humans; In Vitro Techniques; Minocycline; Models, Theoretical; Sulbactam; Tigecycline

2013
The minimal inhibitory concentration for sulbactam was not associated with the outcome of infections caused by carbapenem-resistant Acinetobacter sp. treated with ampicillin/sulbactam.
    Clinics (Sao Paulo, Brazil), 2013, Volume: 68, Issue:4

    Topics: Acinetobacter; Acinetobacter Infections; Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Child; Female; Hospital Mortality; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Sulbactam; Treatment Outcome; Young Adult

2013
Successful treatment of skin and soft tissue infection due to carbapenem-resistant Acinetobacter baumannii by ampicillin-sulbactam and meropenem combination therapy.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2013, Volume: 17, Issue:12

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Ampicillin; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Drug Therapy, Combination; Female; Humans; Meropenem; Microbial Sensitivity Tests; Skin Diseases, Bacterial; Soft Tissue Infections; Sulbactam; Thienamycins; Treatment Outcome

2013
Antibiotic resistance and OXA-type carbapenemases-encoding genes in airborne Acinetobacter baumannii isolated from burn wards.
    Burns : journal of the International Society for Burn Injuries, 2014, Volume: 40, Issue:2

    Topics: Acinetobacter baumannii; Air Microbiology; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Burn Units; Carbapenems; Cefoperazone; Ceftriaxone; Ciprofloxacin; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Imipenem; Microbial Sensitivity Tests; Polymerase Chain Reaction; Repetitive Sequences, Nucleic Acid; Sulbactam

2014
Epidemiology of bloodstream infections caused by Acinetobacter baumannii and impact of drug resistance to both carbapenems and ampicillin-sulbactam on clinical outcomes.
    Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:12

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Carbapenems; Drug Resistance, Multiple, Bacterial; Humans; Michigan; Middle Aged; Retrospective Studies; Sulbactam

2013
In vitro responses of Acinetobacter baumannii to two- and three-drug combinations following exposure to colistin and doripenem.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Carbapenems; Colistin; Doripenem; Drug Administration Schedule; Drug Combinations; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Sulbactam

2014
In vitro synergistic activity of colistin with tigecycline or β-lactam antibiotic/β-lactamase inhibitor combinations against carbapenem-resistant Acinetobacter baumannii.
    The Journal of international medical research, 2013, Volume: 41, Issue:6

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; Carbapenems; Cefoperazone; Colistin; Cross Infection; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam; Tigecycline

2013
Efficacy of sulbactam and its combination with imipenem, colistin and tigecycline in an experimental model of carbapenem-resistant Acinetobacter baumannii sepsis.
    Chemotherapy, 2013, Volume: 59, Issue:5

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Bacterial Load; Carbapenems; Colistin; Disease Models, Animal; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Imipenem; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Minocycline; Sepsis; Sulbactam; Tigecycline; Time Factors

2013
Comparison of colistin-carbapenem, colistin-sulbactam, and colistin plus other antibacterial agents for the treatment of extremely drug-resistant Acinetobacter baumannii bloodstream infections.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2014, Volume: 33, Issue:8

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Bacteremia; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Length of Stay; Male; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Risk Factors; Sulbactam; Treatment Outcome

2014
Colistin-based treatment for extensively drug-resistant Acinetobacter baumannii pneumonia.
    International journal of antimicrobial agents, 2014, Volume: 43, Issue:4

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; APACHE; Carbapenems; Cohort Studies; Colistin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Intensive Care Units; Length of Stay; Male; Middle Aged; Minocycline; Pneumonia, Ventilator-Associated; Retrospective Studies; Sulbactam; Tigecycline; Treatment Outcome; Young Adult

2014
A retrospective analysis of carbapenem-resistant Acinetobacter baumannii-mediated nosocomial pneumonia and the in vitro therapeutic benefit of cefoperazone/sulbactam.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2014, Volume: 23

    Topics: Acinetobacter baumannii; Aged; Aged, 80 and over; Anti-Bacterial Agents; C-Reactive Protein; Carbapenems; Cefoperazone; Cross Infection; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Female; Humans; Levofloxacin; Male; Meropenem; Microbial Sensitivity Tests; Middle Aged; Minocycline; Pneumonia, Bacterial; Retrospective Studies; Sulbactam; Thienamycins

2014
[Pattern dynamics of bacteriemia and sepsis pathogens in ICU patients of emergency service].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2013, Volume: 58, Issue:5-6

    Topics: Acetamides; Acinetobacter; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Candida; Candidiasis; Carbapenems; Cefoperazone; Drug Resistance, Multiple, Bacterial; Enterococcus; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Intensive Care Units; Klebsiella pneumoniae; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Sepsis; Sulbactam; Vancomycin

2013
[In vitro synergistic activity of sulbactam in combination with imipenem, meropenem and cefoperazone against carbapenem-resistant Acinetobacter baumannii isolates].
    Mikrobiyoloji bulteni, 2014, Volume: 48, Issue:2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Cefoperazone; Cross Infection; Drug Combinations; Drug Synergism; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Sulbactam; Thienamycins

2014
[Mechanism of drug resistance of carbapenems-resistant Acinetobacter baumannii and the application of a combination of drugs in vitro].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2014, Volume: 30, Issue:2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Ampicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Cefepime; Cephalosporins; Drug Resistance; Humans; In Vitro Techniques; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Pharmaceutical Preparations; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam; Thienamycins

2014
A nightmare for haematology clinics: extensively drug-resistant (XDR) Acinetobacter baumannnii.
    Le infezioni in medicina, 2014, Volume: 22, Issue:4

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Anti-Bacterial Agents; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Hematology; Hospitals, Teaching; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Prevalence; Retrospective Studies; Sulbactam; Survival Rate; Treatment Outcome; Turkey

2014
Colistin-resistant Acinetobacter baumannii: beyond carbapenem resistance.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, May-01, Volume: 60, Issue:9

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Aged, 80 and over; Ampicillin; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Electronic Health Records; Electrophoresis, Gel, Pulsed-Field; Ethanolamines; Female; Humans; Lipid A; Male; Microbial Sensitivity Tests; Middle Aged; Multilocus Sequence Typing; Pneumonia, Ventilator-Associated; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulbactam

2015
Antimicrobial efficacy of doripenem and its combinations with sulbactam, amikacin, colistin, tigecycline in experimental sepsis of carbapenem-resistant Acinetobacter baumannii.
    The new microbiologica, 2015, Volume: 38, Issue:1

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Amikacin; Animals; Anti-Bacterial Agents; Carbapenems; Colistin; Doripenem; Drug Resistance, Multiple, Bacterial; Humans; Male; Mice; Mice, Inbred BALB C; Minocycline; Sepsis; Sulbactam; Tigecycline

2015
Sulbactam treatment for pneumonia involving multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii complex.
    Infectious diseases (London, England), 2015, Volume: 47, Issue:6

    Topics: Acinetobacter baumannii; Acinetobacter calcoaceticus; Acinetobacter Infections; Adult; Aged; Ampicillin; Anti-Bacterial Agents; Carbapenems; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Pneumonia, Bacterial; Retrospective Studies; Sulbactam; Taiwan; Time Factors

2015
Colistin alone or combined with sulbactam or carbapenem against A. baumannii in ventilator-associated pneumonia.
    Journal of infection in developing countries, 2015, May-18, Volume: 9, Issue:5

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Middle Aged; Pneumonia, Ventilator-Associated; Renal Insufficiency; Retrospective Studies; Sulbactam; Treatment Outcome

2015
Secular trends in Acinetobacter baumannii resistance in respiratory and blood stream specimens in the United States, 2003 to 2012: A survey study.
    Journal of hospital medicine, 2016, Volume: 11, Issue:1

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Ampicillin; Anti-Bacterial Agents; Bacteremia; Carbapenems; Cross Infection; Drug Resistance, Bacterial; Humans; Intensive Care Units; Microbial Sensitivity Tests; Respiratory Tract Infections; Sulbactam; Surveys and Questionnaires; Trimethoprim, Sulfamethoxazole Drug Combination; United States

2016
Acinetobacter baumannii in Southern Croatia: clonal lineages, biofilm formation, and resistance patterns.
    Infectious diseases (London, England), 2015, Volume: 47, Issue:12

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Amikacin; Ampicillin; Anti-Bacterial Agents; Biofilms; Carbapenems; Croatia; Cross Infection; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Genotype; Humans; Intensive Care Units; Microbial Sensitivity Tests; Monte Carlo Method; Respiratory System; Respiratory Tract Infections; Sulbactam; Urine; Wounds and Injuries

2015
[Analysis of the mechanism of drug resistance of VIM-2-type metallo-β-lactamase-producing Acineto- bacter baumannii isolated from burn patients and its homology].
    Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2015, Volume: 31, Issue:3

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Burns; Carbapenems; Drug Resistance, Bacterial; Genes, Bacterial; Humans; Imipenem; Microbial Sensitivity Tests; Sulbactam

2015
LN-1-255, a penicillanic acid sulfone able to inhibit the class D carbapenemase OXA-48.
    The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:8

    Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cloning, Molecular; Cyclic S-Oxides; Escherichia coli; Gene Expression; Kinetics; Klebsiella pneumoniae; Microbial Sensitivity Tests; Penicillins; Protein Binding; Sulbactam

2016
Individual or Combined Effects of Meropenem, Imipenem, Sulbactam, Colistin, and Tigecycline on Biofilm-Embedded Acinetobacter baumannii and Biofilm Architecture.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:8

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Biofilms; Carbapenems; Colistin; Drug Combinations; Drug Resistance, Bacterial; Drug Synergism; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Minocycline; Sulbactam; Thienamycins; Tigecycline

2016
Bacteremia Due to Arthrobacter creatinolyticus in an Elderly Diabetic Man with Acute Cholangitis.
    Japanese journal of infectious diseases, 2017, Mar-24, Volume: 70, Issue:2

    Topics: Aerobiosis; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Arthrobacter; Bacteremia; beta-Lactamase Inhibitors; Carbapenems; Cholangitis; Diabetes Complications; DNA, Bacterial; DNA, Ribosomal; Doripenem; Gram-Positive Bacterial Infections; Humans; Male; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Sulbactam

2017
Determination of synergy between sulbactam, meropenem and colistin in carbapenem-resistant Klebsiella pneumoniae and Acinetobacter baumannii isolates and correlation with the molecular mechanism of resistance.
    Journal of chemotherapy (Florence, Italy), 2016, Volume: 28, Issue:4

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Colistin; Drug Resistance, Bacterial; Drug Synergism; Humans; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Sulbactam; Thienamycins

2016
Tigecycline-based versus sulbactam-based treatment for pneumonia involving multidrug-resistant Acinetobacter calcoaceticus-Acinetobacter baumannii complex.
    BMC infectious diseases, 2016, 08-05, Volume: 16

    Topics: Acinetobacter baumannii; Acinetobacter calcoaceticus; Acinetobacter Infections; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carbapenems; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Minocycline; Pneumonia, Bacterial; Retrospective Studies; Sulbactam; Taiwan; Tigecycline; Treatment Outcome

2016
[Evaluation of the efficacy of colistin/sulbactam combination on carbapenem-resistant Acinetobacter baumannii strains].
    Mikrobiyoloji bulteni, 2016, Volume: 50, Issue:3

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Bacteremia; Bacteriuria; beta-Lactamases; Carbapenems; Colistin; Drug Combinations; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Microbial Sensitivity Tests; Polymerase Chain Reaction; Sulbactam; Trachea; Wound Infection

2016
Trend of extensively drug-resistant Acinetobacter baumannii and the remaining therapeutic options: a multicenter study in Tehran, Iran over a 3-year period.
    Letters in applied microbiology, 2016, Volume: 63, Issue:6

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Humans; Iran; Microbial Sensitivity Tests; Minocycline; Sulbactam; Tigecycline; Tobramycin

2016
Comparison of the efficacies of three empirically-selected antibiotics for treating Acinetobacter baumannii pulmonary infection: experience from a teaching hospital in China

.
    International journal of clinical pharmacology and therapeutics, 2017, Volume: 55, Issue:7

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Aged; Anti-Bacterial Agents; Carbapenems; Cefoperazone; China; Drug Combinations; Drug Resistance, Multiple, Bacterial; Female; Hospitals, Teaching; Humans; Male; Middle Aged; Minocycline; Respiratory Tract Infections; Retrospective Studies; Sputum; Sulbactam; Tigecycline; Time Factors; Treatment Outcome

2017
ETX2514 is a broad-spectrum β-lactamase inhibitor for the treatment of drug-resistant Gram-negative bacteria including Acinetobacter baumannii.
    Nature microbiology, 2017, Jun-30, Volume: 2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Azabicyclo Compounds; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Carbapenems; Dogs; Drug Design; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Mice; Models, Molecular; Penicillin-Binding Proteins; Rats; Sulbactam

2017
[Efficacy of extended-infusion of carbapenem plus sulbactam for ventilator-associated pneumonia caused by extensive drug-resistant
    Zhonghua yi xue za zhi, 2017, Oct-17, Volume: 97, Issue:38

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Humans; Pneumonia, Ventilator-Associated; Retrospective Studies; Sulbactam

2017
Amikacin and cefoperazone/sulbactam alone or in combination against carbapenem-resistant Pseudomonas aeruginosa.
    Diagnostic microbiology and infectious disease, 2018, Volume: 91, Issue:2

    Topics: Amikacin; Animals; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Cefoperazone; Disease Models, Animal; Drug Therapy, Combination; Female; Humans; Luminescent Measurements; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Sulbactam

2018
Comparison of empirical therapy with cefoperazone/sulbactam or a carbapenem for bloodstream infections due to ESBL-producing Enterobacteriaceae.
    The Journal of antimicrobial chemotherapy, 2018, 11-01, Volume: 73, Issue:11

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Carbapenems; Case-Control Studies; Cefoperazone; China; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Sulbactam

2018
Trimethoprim-sulfamethoxazole vs. colistin or ampicillin-sulbactam for the treatment of carbapenem-resistant Acinetobacter baumannii: A retrospective matched cohort study.
    Journal of global antimicrobial resistance, 2019, Volume: 17

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Aged; Ampicillin; Anti-Bacterial Agents; Carbapenems; Colistin; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Middle Aged; Retrospective Studies; Shock, Septic; Sulbactam; Trimethoprim, Sulfamethoxazole Drug Combination

2019
Molecular Detection of Carbapenem Resistance in Acinetobacter Baumannii Isolated From Patients in Khorramabad City, Iran.
    Infectious disorders drug targets, 2020, Volume: 20, Issue:4

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Ampicillin; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Colistin; Cross-Sectional Studies; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Iran; Microbial Sensitivity Tests; Sulbactam

2020
Synergistic Activities of Colistin Combinations with Meropenem, Sulbactam, Minocycline, Disodium Fosfomycin, or Vancomycin Against Different Clones of Carbapenem-Resistant
    Microbial drug resistance (Larchmont, N.Y.), 2020, Volume: 26, Issue:5

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacteriological Techniques; Carbapenems; Colistin; Drug Combinations; Drug Resistance, Bacterial; Drug Synergism; Fosfomycin; Humans; Meropenem; Minocycline; Sulbactam; Vancomycin

2020
In vitro interactions of ambroxol hydrochloride or amlodipine in combination with antibacterial agents against carbapenem-resistant Acinetobacter baumannii.
    Letters in applied microbiology, 2020, Volume: 70, Issue:3

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Ambroxol; Amlodipine; Anti-Bacterial Agents; Carbapenems; Cefoperazone; Cilastatin, Imipenem Drug Combination; Drug Combinations; Drug Resistance, Bacterial; Drug Synergism; Humans; Meropenem; Microbial Sensitivity Tests; Sulbactam; Thienamycins

2020
In vitro activity of sulbactam/durlobactam against global isolates of carbapenem-resistant Acinetobacter baumannii.
    The Journal of antimicrobial chemotherapy, 2020, 09-01, Volume: 75, Issue:9

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Carbapenems; Colistin; Humans; Microbial Sensitivity Tests; Sulbactam

2020
Non-polymyxin-based combinations as potential alternatives in treatment against carbapenem-resistant Acinetobacter baumannii infections.
    International journal of antimicrobial agents, 2020, Volume: 56, Issue:4

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Carbapenems; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Fosfomycin; Humans; Meropenem; Microbial Sensitivity Tests; Polymyxins; Sulbactam

2020
Evaluation of First-Dose, Intravenous Push Penicillins and Carbapenems in the Emergency Department.
    Journal of pharmacy practice, 2022, Volume: 35, Issue:3

    Topics: Ampicillin; Anti-Bacterial Agents; Carbapenems; Emergency Service, Hospital; Ertapenem; Humans; Penicillins; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Sulbactam

2022
In vitro activity of sulbactam-durlobactam against carbapenem-resistant Acinetobacter baumannii and mechanisms of resistance.
    Journal of global antimicrobial resistance, 2022, Volume: 30

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Azabicyclo Compounds; Carbapenems; Drug Combinations; Humans; Microbial Sensitivity Tests; Sulbactam

2022
Zidebactam restores sulbactam susceptibility against carbapenem-resistant
    Frontiers in cellular and infection microbiology, 2022, Volume: 12

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Azabicyclo Compounds; Carbapenems; Cyclooctanes; Microbial Sensitivity Tests; Piperidines; Sulbactam

2022
Analysis of a novel class A β-lactamase OKP-B-6 of Klebsiella quasipneumoniae: structural characterisation and interaction with commercially available drugs.
    Memorias do Instituto Oswaldo Cruz, 2022, Volume: 117

    Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Klebsiella; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Docking Simulation; Sulbactam; Sulfhydryl Reagents; Tazobactam

2022
Whole-cell vaccine candidates induce a protective response against virulent
    Frontiers in immunology, 2022, Volume: 13

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Carbapenems; Colistin; Humans; Mice; Sulbactam

2022
Sulbactam combined with tigecycline improves outcomes in patients with severe multidrug-resistant Acinetobacter baumannii pneumonia.
    BMC infectious diseases, 2022, Oct-21, Volume: 22, Issue:1

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Anti-Infective Agents; Carbapenems; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Pneumonia; Retrospective Studies; Sulbactam; Tigecycline

2022
Evaluation of combination therapies with colistin in an experimental mouse pneumonia model induced by carbapenem-resistant Acinetobacter baumannii strain.
    Fundamental & clinical pharmacology, 2023, Volume: 37, Issue:4

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Animals; Anti-Bacterial Agents; Carbapenems; Colistin; Imipenem; Mice; Microbial Sensitivity Tests; Sulbactam; Tigecycline

2023
Sulbactam-durlobactam: A Step Forward in Treating Carbapenem-Resistant Acinetobacter baumannii (CRAB) Infections.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2023, 05-01, Volume: 76, Issue:Suppl 2

    Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Carbapenems; Humans; Microbial Sensitivity Tests; Sulbactam

2023
Cefotaxime/sulbactam plus gentamicin as a potential carbapenem- and amikacin-sparing first-line combination for neonatal sepsis in high ESBL prevalence settings.
    The Journal of antimicrobial chemotherapy, 2023, 08-02, Volume: 78, Issue:8

    Topics: Amikacin; Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefotaxime; Escherichia coli; Gentamicins; Humans; Infant, Newborn; Microbial Sensitivity Tests; Neonatal Sepsis; Prevalence; Sulbactam

2023
Clinical outcomes and safety of intravenous polymyxin B-based treatment in critically ill patients with carbapenem-resistant Acinetobacter baumannii nosocomial pneumonia.
    International journal of antimicrobial agents, 2023, Volume: 62, Issue:2

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Carbapenems; Critical Illness; Cross Infection; Healthcare-Associated Pneumonia; Humans; Polymyxin B; Retrospective Studies; Sulbactam; Tigecycline

2023
Clinical Treatment Options for Carbapenem-Resistant Gram-Negative Infections in China: a Single Center Real-World Experience.
    Clinical laboratory, 2023, Jun-01, Volume: 69, Issue:6

    Topics: Carbapenems; Cefoperazone; China; Humans; Retrospective Studies; Sulbactam

2023