carbapenems has been researched along with serine in 10 studies
| Studies (carbapenems) | Trials (carbapenems) | Recent Studies (post-2010) (carbapenems) | Studies (serine) | Trials (serine) | Recent Studies (post-2010) (serine) |
|---|---|---|---|---|---|
| 7,355 | 147 | 5,277 | 23,914 | 115 | 6,084 |
| Protein | Taxonomy | carbapenems (IC50) | serine (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Electrophorus electricus (electric eel) | 0.015 | |
| Cholinesterase | Equus caballus (horse) | 0.016 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 3 (30.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nakae, T; Ono, T; Yoneyama, H; Yoshihara, E | 1 |
| Collatz, E; Jarlier, V; Naas, T; Nordmann, P; Sougakoff, W | 1 |
| Carenbauer, AL; Crowder, MW; Garrity, JD; Periyannan, G; Yates, RB | 1 |
| Hart, BP; Rapoport, H; Verma, SK | 1 |
| Citron, DM; Goldstein, EJ; Merriam, CV; Tyrrell, KL | 1 |
| Bjerga, GE; Edvardsen, KS; Leiros, HK; Samuelsen, Ø | 1 |
| Das, S; Fauntleroy, KA; Hayden, JA; Jenkins, SG; Johnson, JK; Mazur, C; Satlin, MJ; Sfeir, MM; Simner, PJ; Westblade, LF | 1 |
| Chen, C; Oelschlaeger, P; Wang, C; Wang, D; Wang, Q; Xu, H; Yang, KW; Zhao, A | 1 |
| Mensa, J; Soriano, A | 1 |
| Li, H; Liang, X; Liu, W; Yan, Q; Zhong, Y | 1 |
2 review(s) available for carbapenems and serine
| Article | Year |
|---|---|
Structure and Mechanism-Guided Design of Dual Serine/Metallo-Carbapenemase Inhibitors.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Serine | 2022 |
Mechanism of action of cefiderocol.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cattle; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Gram-Negative Bacteria; Iron; Quinolones; Serine; Tetracyclines | 2022 |
8 other study(ies) available for carbapenems and serine
| Article | Year |
|---|---|
Identification of the catalytic triad of the protein D2 protease in Pseudomonas aeruginosa.
Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Carbapenems; Catalysis; Endopeptidases; Glutamine; Histidine; Imipenem; Ion Channels; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Porins; Pseudomonas aeruginosa; Serine | 1998 |
Role of ser-237 in the substrate specificity of the carbapenem-hydrolyzing class A beta-lactamase Sme-1.
Topics: Alanine; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Enterobacteriaceae; Escherichia coli; Hydrolysis; Imipenem; Mutagenesis, Site-Directed; Mutation; Serine; Substrate Specificity | 1999 |
Probing substrate binding to metallo-beta-lactamase L1 from Stenotrophomonas maltophilia by using site-directed mutagenesis.
Topics: Asparagine; beta-Lactamases; Binding Sites; Carbapenems; Cephalosporins; Computational Biology; Isoleucine; Kinetics; Metals; Models, Molecular; Mutagenesis, Site-Directed; Penicillins; Phenylalanine; Protein Binding; Serine; Stenotrophomonas maltophilia; Tyrosine | 2002 |
Asymmetric synthesis of the carbapenam core from serine.
Topics: Carbapenems; Indicators and Reagents; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Pyrrolidines; Serine; Stereoisomerism | 2003 |
In vitro activity of Biapenem plus RPX7009, a carbapenem combined with a serine β-lactamase inhibitor, against anaerobic bacteria.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; beta-Lactamase Inhibitors; Carbapenems; Drug Resistance, Bacterial; Drug Therapy, Combination; Enzyme Inhibitors; Gram-Positive Bacteria; Humans; Imipenem; Microbial Sensitivity Tests; Prevotella; Serine; Thienamycins | 2013 |
Structural and biochemical characterization of VIM-26 shows that Leu224 has implications for the substrate specificity of VIM metallo-β-lactamases.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Binding Sites; Carbapenems; Catalysis; Cephalosporins; Crystallography, X-Ray; Drug Resistance, Bacterial; Ions; Klebsiella pneumoniae; Leucine; Penicillins; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Recombinant Proteins; Serine; Substrate Specificity | 2015 |
EDTA-Modified Carbapenem Inactivation Method: a Phenotypic Method for Detecting Metallo-β-Lactamase-Producing
Topics: Anti-Bacterial Agents; beta-Lactamases; Biological Assay; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Edetic Acid; Metals; Microbial Sensitivity Tests; Phenotype; Sensitivity and Specificity; Serine | 2019 |
Molecular epidemiology of clinical isolation of carbapenem-resistant Enterobacterales and application of carbapenemase inhibitor enhancement test.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Escherichia coli; Humans; Klebsiella pneumoniae; Microbial Sensitivity Tests; Molecular Epidemiology; Serine | 2023 |