Compounds > carbapenems
Page last updated: 2024-09-04

carbapenems and quercetin

carbapenems has been researched along with quercetin in 4 studies

Compound Research Comparison

Studies
(carbapenems)		Trials
(carbapenems)		Recent Studies (post-2010)
(carbapenems)		Studies
(quercetin)		Trials
(quercetin)		Recent Studies (post-2010) (quercetin)
7,3551475,27712,4032397,510

Protein Interaction Comparison

ProteinTaxonomycarbapenems (IC50)quercetin (IC50)
Neuraminidase Influenza A virus (A/Wilson-Smith/1933(H1N1))2.2
hexokinaseTrypanosoma brucei brucei TREU92722.378
Maltase-glucoamylase, intestinalHomo sapiens (human)7.8
NUAK family SNF1-like kinase 1Homo sapiens (human)5.09
Lysine-specific histone demethylase 1AHomo sapiens (human)1.26
B2 bradykinin receptorCavia porcellus (domestic guinea pig)4
Arginase Leishmania amazonensis4
Epidermal growth factor receptorHomo sapiens (human)0.9
ProthrombinHomo sapiens (human)1.5
Cationic trypsinBos taurus (cattle)7.1
Beta-lactamaseEscherichia coli K-124
NeuraminidaseInfluenza A virus (A/Puerto Rico/8/1934(H1N1))7.75
Interstitial collagenaseHomo sapiens (human)1.49
Phospholipase A2Homo sapiens (human)2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)9
Cytochrome P450 1A1Homo sapiens (human)5.5455
Amyloid-beta precursor proteinHomo sapiens (human)7.94
MyeloperoxidaseHomo sapiens (human)1.6975
Cytochrome P450 1A2Homo sapiens (human)4.097
Cyclin-dependent kinase 1Homo sapiens (human)0.45
Glycogen phosphorylase, liver formHomo sapiens (human)4.8
Epoxide hydrolase 1 Homo sapiens (human)7
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)6.6417
Insulin-like growth factor 1 receptorHomo sapiens (human)0.3
Neutrophil elastaseHomo sapiens (human)22.378
72 kDa type IV collagenaseHomo sapiens (human)6.68
Stromelysin-1Homo sapiens (human)5.57
Hepatocyte growth factor receptorHomo sapiens (human)0.58
Cytochrome P450 3A4Homo sapiens (human)7
Polyunsaturated fatty acid 5-lipoxygenaseHomo sapiens (human)2.6975
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus8.1
Lysosomal alpha-glucosidaseHomo sapiens (human)7.8
SialidaseClostridium perfringens4.7333
Malate dehydrogenaseThermus thermophilus6
Cytochrome P450 2C8Homo sapiens (human)7
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.7686
AromataseHomo sapiens (human)0.012
Polyunsaturated fatty acid 5-lipoxygenaseRattus norvegicus (Norway rat)1.95
Polyunsaturated fatty acid lipoxygenase ALOX15Oryctolagus cuniculus (rabbit)0.43
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.12
Sucrase-isomaltase, intestinalHomo sapiens (human)7.8
Matrix metalloproteinase-9Homo sapiens (human)0.8919
Serine/threonine-protein kinase B-rafHomo sapiens (human)7.589
Aldo-keto reductase family 1 member B1Homo sapiens (human)2.2141
G2/mitotic-specific cyclin-BMarthasterias glacialis (spiny starfish)2.1
Polyunsaturated fatty acid lipoxygenase ALOX15Homo sapiens (human)2.2
Aldo-keto reductase family 1 member B1Bos taurus (cattle)2.85
Polyunsaturated fatty acid lipoxygenase ALOX12Homo sapiens (human)0.44
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)2.1
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)4
Casein kinase II subunit alpha'Homo sapiens (human)1.65
Amine oxidase [flavin-containing] AHomo sapiens (human)2.62
Amine oxidase [flavin-containing] A Bos taurus (cattle)0.01
C-X-C chemokine receptor type 1Homo sapiens (human)4.7559
Dipeptidyl peptidase 4Homo sapiens (human)2.92
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)3.8
Proteasome subunit beta type-5Homo sapiens (human)2.75
Vasopressin V2 receptorHomo sapiens (human)6.6548
Tyrosine-protein kinase receptor UFOHomo sapiens (human)0.96
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)1
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)5.39
Bifunctional epoxide hydrolase 2Homo sapiens (human)7
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.97
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.59
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)1.54
Kappa-type opioid receptorCavia porcellus (domestic guinea pig)1
Collagenase 3Homo sapiens (human)8.46
1-deoxy-D-xylulose 5-phosphate reductoisomeraseEscherichia coli K-121.9
Xanthine dehydrogenase/oxidaseHomo sapiens (human)3.04
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)3.8
Glycogen synthase kinase-3 alphaHomo sapiens (human)2.1
Glycogen synthase kinase-3 betaHomo sapiens (human)2.1
Aldo-keto reductase family 1 member A1Rattus norvegicus (Norway rat)2.32
C-C chemokine receptor type 4Homo sapiens (human)10
Serine/threonine-protein kinase Nek2Homo sapiens (human)5.73
Serine/threonine-protein kinase PLK1Homo sapiens (human)5.75
Death-associated protein kinase 1Homo sapiens (human)8.9
Mitogen-activated protein kinase 10Homo sapiens (human)2.88
Beta-secretase 1Homo sapiens (human)6.05
Casein kinase II subunit betaHomo sapiens (human)1.65
Casein kinase II subunit alphaHomo sapiens (human)1.65
LactoperoxidaseBos taurus (cattle)6.1
Cyclin-dependent kinase 6Homo sapiens (human)2.1
Cyclin-dependent-like kinase 5 Homo sapiens (human)2.1
Cyclin homologHerpesvirus saimiri (strain 11)2.1
Lactoylglutathione lyaseHomo sapiens (human)3.2
Focal adhesion kinase 1Homo sapiens (human)1.2
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)3
ELAV-like protein 3Homo sapiens (human)1.8
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)2.1
ELAV-like protein 1Homo sapiens (human)1.4
Serine/threonine-protein kinase N1Homo sapiens (human)5.8
Mitogen-activated protein kinase 14Homo sapiens (human)2.88
Cytochrome P450 1B1Homo sapiens (human)1.1108
Probable maltase-glucoamylase 2Homo sapiens (human)7.8
Monocarboxylate transporter 2Rattus norvegicus (Norway rat)5
Integrase Human immunodeficiency virus 14.3
Casein kinase II subunit alpha 3Homo sapiens (human)0.55
Inositol polyphosphate multikinaseHomo sapiens (human)2.3
Aldo-keto reductase family 1 member C21Mus musculus (house mouse)6.9
Enoyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)1.8333
3-oxoacyl-acyl-carrier protein reductase Plasmodium falciparum (malaria parasite P. falciparum)5.4
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)Plasmodium falciparum (malaria parasite P. falciparum)1.5
Aurora kinase BHomo sapiens (human)2.435
Cyclin-dependent kinase 1Oryzias latipes (Japanese medaka)2.1
Serine/threonine-protein kinase Nek6Homo sapiens (human)4.23
NADPH oxidase 4Homo sapiens (human)0.68
Inositol hexakisphosphate kinase 2Homo sapiens (human)0.7
Short transient receptor potential channel 5Homo sapiens (human)6.5
ALK tyrosine kinase receptorHomo sapiens (human)3.32
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)7.25

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (50.00)24.3611
2020's2 (50.00)2.80

Authors

AuthorsStudies
Arora, R; Chawla, R; Goel, R; Narula, A; Sharma, RK; Thakur, P1
Pal, A; Tripathi, A2
Aydemir, Ö; Ayhancı, T; Köroğlu, M; Ormanoğlu, G; Zengin, M1

Other Studies

4 other study(ies) available for carbapenems and quercetin

ArticleYear
In vitro bactericidal activity of Berberis aristata extract against clinical isolates of carbapenem-resistant Escherichia coli.
    Journal of complementary & integrative medicine, 2016, Sep-01, Volume: 13, Issue:3

    Topics: Alkaloids; Anti-Bacterial Agents; Berberis; beta-Lactamases; Carbapenems; Drug Resistance, Bacterial; Escherichia coli; Phenols; Plant Extracts; Quercetin; Terpenes

2016
Quercetin potentiates meropenem activity among pathogenic carbapenem-resistant Pseudomonas aeruginosa and Acinetobacter baumannii.
    Journal of applied microbiology, 2019, Volume: 127, Issue:4

    Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; Carbapenems; Drug Resistance, Bacterial; Drug Synergism; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Quercetin

2019
Quercetin inhibits carbapenemase and efflux pump activities among carbapenem-resistant Gram-negative bacteria.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2020, Volume: 128, Issue:3

    Topics: Amino Acids; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Molecular Docking Simulation; Quercetin

2020
Investigation of in vitro efficacy of quercetin-meropenem combination in carbapenemase-producing Klebsiella pneumoniae isolates.
    Journal of infection in developing countries, 2023, 09-30, Volume: 17, Issue:9

    Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Humans; Klebsiella Infections; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Quercetin

2023