carbapenems has been researched along with probenecid in 4 studies
| Studies (carbapenems) | Trials (carbapenems) | Recent Studies (post-2010) (carbapenems) | Studies (probenecid) | Trials (probenecid) | Recent Studies (post-2010) (probenecid) |
|---|---|---|---|---|---|
| 7,355 | 147 | 5,277 | 3,664 | 292 | 375 |
| Protein | Taxonomy | carbapenems (IC50) | probenecid (IC50) |
|---|---|---|---|
| Solute carrier family 22 member 8 | Mus musculus (house mouse) | 3.02 | |
| Solute carrier family 22 member 6 | Homo sapiens (human) | 6.85 | |
| Solute carrier family 22 member 8 | Homo sapiens (human) | 6.965 | |
| Solute carrier family 22 member 8 | Rattus norvegicus (Norway rat) | 6.03 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bastain, W; Bax, RP; Featherstone, A; Haworth, SJ; Hutchison, M; Wilkinson, DM | 1 |
| Kim, SH; Kim, WB; Lee, MG | 2 |
| Hamada, N; Nagai, J; Ogawa, K; Takano, M; Yumoto, R | 1 |
1 trial(s) available for carbapenems and probenecid
| Article | Year |
|---|---|
The pharmacokinetics of meropenem in volunteers.
Topics: Adult; Carbapenems; Chromatography, High Pressure Liquid; Drug Interactions; Half-Life; Humans; Male; Meropenem; Probenecid; Reference Values; Thienamycins | 1989 |
3 other study(ies) available for carbapenems and probenecid
| Article | Year |
|---|---|
No effect of probenecid on the renal excretion mechanism of a new carbapenem, DA-1131, in dogs.
Topics: Absorption; Animals; Carbapenems; Dogs; Kidney Tubules; Male; Probenecid; Renal Agents | 1998 |
Effect of probenecid on the renal excretion mechanism of a new carbapenem, DA-1131, in rats and rabbits.
Topics: Animals; Area Under Curve; Carbapenems; Chromatography, High Pressure Liquid; Creatinine; Drug Interactions; Injections, Intravenous; Male; Probenecid; Rabbits; Rats; Rats, Sprague-Dawley | 1999 |
Interaction of valproic acid and carbapenem antibiotics with multidrug resistance-associated proteins in rat erythrocyte membranes.
Topics: Adenosine Triphosphate; Animals; Anti-Bacterial Agents; Carbapenems; Dose-Response Relationship, Drug; Drug Interactions; Erythrocyte Membrane; Glutathione; Indomethacin; Methotrexate; Multidrug Resistance-Associated Proteins; Probenecid; Rats; Transport Vesicles; Valproic Acid | 2006 |