carbapenems has been researched along with glutamic acid in 5 studies
| Studies (carbapenems) | Trials (carbapenems) | Recent Studies (post-2010) (carbapenems) | Studies (glutamic acid) | Trials (glutamic acid) | Recent Studies (post-2010) (glutamic acid) |
|---|---|---|---|---|---|
| 7,355 | 147 | 5,277 | 41,757 | 452 | 12,876 |
| Protein | Taxonomy | carbapenems (IC50) | glutamic acid (IC50) |
|---|---|---|---|
| Chain A, GLUTAMATE RECEPTOR SUBUNIT 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain A, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Chain B, Glutamate Receptor Subunit 2 | Rattus norvegicus (Norway rat) | 0.821 | |
| Metabotropic glutamate receptor 8 | Homo sapiens (human) | 0.0057 | |
| Glutamate receptor ionotropic, NMDA 2D | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor 1 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 2 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 3 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor 4 | Rattus norvegicus (Norway rat) | 0.5885 | |
| Glutamate receptor ionotropic, kainate 1 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 2 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor 1 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 2 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor 3 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, kainate 3 | Rattus norvegicus (Norway rat) | 0.38 | |
| Excitatory amino acid transporter 1 | Homo sapiens (human) | 207 | |
| Glutamate receptor 4 | Homo sapiens (human) | 0.613 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 4 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2C | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, kainate 5 | Rattus norvegicus (Norway rat) | 0.38 | |
| Glutamate receptor ionotropic, NMDA 3A | Homo sapiens (human) | 0.07 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.1533 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.1533 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schofield, CJ; Sleeman, MC | 1 |
| Schofield, CJ; Sleeman, MC; Sorensen, JL | 1 |
| Batchelar, ET; McDonough, MA; Schofield, CJ; Sleeman, MC; Sorensen, JL | 1 |
| He, Y; Jiang, Y; Pan, X; Wong, WT; Zhao, Y | 1 |
| Biswal, S; Ghosh, AS; Issa, B; Kar, D; Kumar, G | 1 |
5 other study(ies) available for carbapenems and glutamic acid
| Article | Year |
|---|---|
Carboxymethylproline synthase (CarB), an unusual carbon-carbon bond-forming enzyme of the crotonase superfamily involved in carbapenem biosynthesis.
Topics: Acetyl Coenzyme A; Amino Acid Sequence; Carbapenems; Carbon; Carbon-Carbon Lyases; Chromatography, Gel; Circular Dichroism; Cloning, Molecular; Dithionitrobenzoic Acid; Electrophoresis, Polyacrylamide Gel; Enoyl-CoA Hydratase; Glutamates; Glutamic Acid; Kinetics; Lactams; Magnetic Resonance Spectroscopy; Malonyl Coenzyme A; Mass Spectrometry; Models, Chemical; Molecular Sequence Data; Pectobacterium; Protein Binding; Recombinant Proteins; Sequence Homology, Amino Acid; Stereoisomerism; Thienamycins | 2004 |
Synthesis of deuterium labelled L- and D-glutamate semialdehydes and their evaluation as substrates for carboxymethylproline synthase (CarB)--implications for carbapenem biosynthesis.
Topics: Aldehydes; Carbapenems; Carbon-Carbon Lyases; Deuterium; Glutamic Acid; Isotope Labeling; Molecular Structure; Stereoisomerism | 2005 |
Structural and mechanistic studies on carboxymethylproline synthase (CarB), a unique member of the crotonase superfamily catalyzing the first step in carbapenem biosynthesis.
Topics: Aldehydes; Anhydrides; Binding Sites; Carbapenems; Carbon-Carbon Lyases; Catalysis; Chromatography, Liquid; Crystallography, X-Ray; Enoyl-CoA Hydratase; Escherichia coli; Esters; Glutamates; Glutamic Acid; Histidine; Hydrogen Bonding; Mass Spectrometry; Models, Chemical; Models, Molecular; Mutagenesis; Proline; Protein Binding; Protein Conformation; Protein Structure, Secondary; Selenomethionine; Substrate Specificity; Thiolester Hydrolases; Trypsin | 2005 |
Perturbing the general base residue Glu166 in the active site of class A β-lactamase leads to enhanced carbapenem binding and acylation.
Topics: Acylation; Amino Acid Substitution; Bacillus; beta-Lactamases; Binding Sites; Carbapenems; Catalytic Domain; Cephaloridine; Crystallography, X-Ray; Glutamic Acid; Kinetics; Meropenem; Models, Molecular; Protein Conformation; Thienamycins | 2014 |
E152A substitution drastically affects NDM-5 activity.
Topics: Amino Acid Substitution; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Catalytic Domain; Drug Resistance, Multiple, Bacterial; Escherichia coli; Glutamic Acid; Hydrolysis; Kinetics; Klebsiella Infections; Klebsiella pneumoniae; Mutation | 2017 |