Compounds > carbapenems
Page last updated: 2024-09-04

carbapenems and fce 22891

carbapenems has been researched along with fce 22891 in 11 studies

Compound Research Comparison

Studies
(carbapenems)		Trials
(carbapenems)		Recent Studies (post-2010)
(carbapenems)		Studies
(fce 22891)		Trials
(fce 22891)		Recent Studies (post-2010) (fce 22891)
7,3551475,2771940

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's6 (54.55)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boobis, A; Davies, D; Efthymiopoulos, C; Sassella, D; Strolin Benedetti, M1
Lewis, DA; Lovering, AM; MacGowan, AP; Reeves, DS1
Burman, LA; Cassinelli, G; Corigli, R; Dornbusch, K; Franceschi, G; Norrby, SR; Sassella, D1
Alpegiani, M; Battistini, C; Bedeschi, A; Della Bruna, C; Franceschi, G; Perrone, E; Zarini, F1
Castellani, P; Della Bruna, C; Jabes, D; Rossi, R; Younes, G1
Brughera, M; Ferrari, ML; Mazué, G; Nava, A; Scampini, G1
Andrews, JM; Ashby, JP; Wallbridge, D; Webberley, JM; Wise, R1
Brughera, M; Dayan, AD; Iatropoulos, MJ; Mazue, G; Newman, AJ; Scampini, G1
Banno, K; Maki, T; Matsuoka, M; Sato, T1
Banno, K; Imado, N; Maki, T; Matsuoka, M; Sato, T1

Reviews

1 review(s) available for carbapenems and fce 22891

ArticleYear
Synthesis and antimicrobial spectrum of FCE 22101 and its orally available ester FCE 22891.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 23 Suppl C

    Topics: Anti-Bacterial Agents; Bacteria; Carbapenems; Chemical Phenomena; Chemistry; Lactams

1989

Trials

1 trial(s) available for carbapenems and fce 22891

ArticleYear
Pharmacokinetics in healthy subjects of FCE 22101 and its acetoxymethyl ester, FCE 22891: effect of co-administration of imipenem/cilastatin on the renal metabolism of FCE 22101.
    The Journal of antimicrobial chemotherapy, 1990, Volume: 25, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Carbapenems; Chromatography, High Pressure Liquid; Cilastatin; Cilastatin, Imipenem Drug Combination; Dipeptidases; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Humans; Imipenem; Kidney; Lactams; Male; Reference Values

1990

Other Studies

9 other study(ies) available for carbapenems and fce 22891

ArticleYear
Pharmacokinetics of [14C]FCE 22891, a penem antibiotic, following oral administration to healthy volunteers.
    Antimicrobial agents and chemotherapy, 1992, Volume: 36, Issue:9

    Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Carbapenems; Feces; Humans; Intestinal Absorption; Lactams; Male; Prodrugs

1992
Pharmacokinetics and metabolism of FCE 22101 following its administration as the oral pro-drug FCE 22891.
    The Journal of antimicrobial chemotherapy, 1992, Volume: 29, Issue:2

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Carbapenems; Humans; Lactams; Male; Middle Aged; Prodrugs

1992
FCE 22101 and FCE 22891: in-vitro antibacterial activity at concentrations simulating human plasma levels following intravenous, intramuscular and oral administration.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 23 Suppl C

    Topics: Administration, Oral; Anti-Bacterial Agents; Bacteria; Carbapenems; Culture Media; Enterobacter; Escherichia coli; Humans; Injections, Intramuscular; Injections, Intravenous; Lactams; Microbial Sensitivity Tests; Models, Biological; Staphylococcus aureus; Streptococcus

1989
FCE 22101, a new penem antibacterial, and its oral prodrug, FCE 22891. Twenty-eighth Interscience Conference on Antimicrobial Agents and Chemotherapy. Los Angeles, California, 23-26 October 1988.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 23 Suppl C

    Topics: Animals; Anti-Bacterial Agents; Carbapenems; Humans; Lactams

1989
Toxicological profile of FCE 22101 and its orally available ester FCE 22891.
    The Journal of antimicrobial chemotherapy, 1989, Volume: 23 Suppl C

    Topics: Animals; Anti-Bacterial Agents; Carbapenems; Female; Kidney Diseases; Lactams; Lethal Dose 50; Male; Mice; Mice, Inbred Strains; Rats; Time Factors

1989
The pharmacokinetics and tissue penetration of FCE 22101 following intravenous and oral administration.
    The Journal of antimicrobial chemotherapy, 1988, Volume: 21, Issue:4

    Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Blister; Carbapenems; Half-Life; Humans; Injections, Intravenous; Lactams; Male; Middle Aged; Time Factors; Tissue Distribution

1988
Urinary bladder hyperplasia in the rat: non-specific pathogenetic considerations using a beta-lactam antibiotic.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 1994, Volume: 46, Issue:4-5

    Topics: Animals; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Hyperplasia; Kidney; Lactams; Male; Precancerous Conditions; Rats; Time Factors; Urinary Bladder; Urinary Bladder Diseases; Urinary Bladder Neoplasms; Urine

1994
Liquid chromatographic analysis of penem antibiotic FCE22101 in biological fluids with a liquid-liquid extraction procedure.
    Journal of chromatography. B, Biomedical applications, 1996, Oct-25, Volume: 685, Issue:2

    Topics: Acetates; Administration, Oral; Anti-Bacterial Agents; Calibration; Carbapenems; Chromatography, High Pressure Liquid; Humans; Lactams; Linear Models; Osmolar Concentration; Prodrugs; Reproducibility of Results; Sensitivity and Specificity; Time Factors

1996
Simultaneous determination of an active metabolite and open-ring metabolites by high performance liquid chromatography and pharmacokinetic studies of a penem antibiotic, FCE22891, in dogs.
    Journal of pharmaceutical and biomedical analysis, 1998, Volume: 17, Issue:2

    Topics: Acetylcarnitine; Administration, Oral; Animals; Anti-Bacterial Agents; Area Under Curve; Butyrates; Carbapenems; Chromatography, High Pressure Liquid; Dogs; Formaldehyde; Hydrogen-Ion Concentration; Lactams; Prodrugs; Reproducibility of Results; Thiazoles

1998