Page last updated: 2024-09-04

carbapenems and cefepime

carbapenems has been researched along with cefepime in 71 studies

Compound Research Comparison

Studies (carbapenems)	Trials (carbapenems)	Recent Studies (post-2010) (carbapenems)	Studies (cefepime)	Trials (cefepime)	Recent Studies (post-2010) (cefepime)
7,355	147	5,277	1,737	186	684

Research

Studies (71)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (2.82)	18.2507
2000's	17 (23.94)	29.6817
2010's	30 (42.25)	24.3611
2020's	22 (30.99)	2.80

Authors

Authors	Studies
Devalckenaere, A; Husson, MO; Izard, D; Vachée, A	1
Verbist, L; Verhaegen, J	1
Jacolot, A; Leotard, S; Louchahi, K; Mimoz, O; Nordmann, P; Padoin, C; Petitjean, O	1
Bantar, C; Di Chiara, M; Nicola, F; Relloso, S; Smayevsky, J	1
Christenson, JC; Daly, JA; Korgenski, EK	1
Barry, AL; Brown, SD; Fuchs, PC	1
Endo, H; Jinbo, K; Nishinari, C; Suzuki, Y; Tamura, C	1
Gondoh, H; Hanada, S; Ikeda, S; Imamura, Y; Izumi, Y; Kawano, F; Masuda, M; Matsuishi, E; Matsuoka, H; Okamura, S; Saburi, Y; Shibuya, T; Tamura, K; Tsukada, J; Uike, N; Utsunomiya, A	1
Biedenbach, DJ; Gales, AC; Jones, RN	1
Song, A	1
Bernabéu-Wittel, M; de Cueto, M; del Carmen Conejo, M; García, I; Jiménez-Mejías, ME; Martínez-Martínez, L; Pachón, J; Pachón-Ibáñez, ME; Pascual, A; Pichardo, C	1
Fraser, A; Leibovici, L; Paul, M; Yahav, D	1
Baraniak, A; Bossaert, L; Demey, HE; Gniadkowski, M; Goethaert, K; Goossens, H; Ieven, M; Jansens, H; Jorens, PG; Lammens, C; Van Herck, K; Van Looveren, M	1
Fernández-Cuenca, F; Martínez-Martínez, L; Pascual, A; Rodríguez-Martínez, JM	1
Cheng, KC; Chuang, YC; Huang, GC; Wu, LT; Yu, WL	1
Kawano, F; Koga, S; Matsuoka, H; Okamura, S; Shibata, K; Shirahashi, A; Suzushima, H; Tamura, K; Tsukamoto, A; Uozumi, K; Yamashita, K	1
Chai, D; Li, Z; Pei, F; Tong, W; Wang, R	1
Alp, E; Aygen, B; Metan, G; Sumerkan, B	1
Appelbaum, PC; Glupczynski, Y; Lemaire, S; Olivier, A; Tulkens, PM; Van Bambeke, F	1
Amicosante, G; Falcone, M; Mancini, C; Mezzatesta, ML; Perilli, M; Stefani, S; Venditti, M	1
Doherty, JA; Khan, J; Kollef, MH; Micek, ST; Pervez, M; Reichley, RM; Welch, EC	1
Appelbaum, PC; Armstrong, ES; Kosowska-Shick, K; Kubo, A; Lin, G; Pankuch, GA	1
Cabot, G; Macia, MD; Martínez-Martínez, L; Moya, B; Ocampo-Sosa, AA; Oliver, A; Peña, C; Rodríguez, C; Suárez, C; Tubau, F; Zamorano, L	1
Beloborodov, VB; Gruver, KP; Kuz'menko, TN	1
Acosta, F; Cottagnoud, M; Cottagnoud, P; Egerman, U; Laeuffer, JM; Stucki, A	1
Hino, M; Kanamaru, A; Masaoka, T; Nakagawa, Y; Ohta, K; Ohyashiki, K; Suzuki, K; Tamura, K; Urabe, A	1
Hsueh, PR; Huang, WH; Ko, WC; Lee, CC; Lee, NY; Tsui, KC	1
Chen, JH; He, YQ; Liu, S; Wan, YF; Xu, CQ; Ye, ML; Zheng, YL; Zhou, LY	1
Goff, DA; Nicolau, DP	1
Baghdady, N; Ferraro, MJ; Galar, A; Guzmán-Suarez, BB; Hooper, DC; Kubiak, DW; Marty, FM; O'Brien, TF; Siedner, MJ	1
Wu, H; Xie, W; Ye, Z; Zhang, W; Zhao, C	1
Achkar, M; Charrouf, FO; Dabboussia, F; Hamze, M; Mallat, H	1
Bethel, CR; Bonomo, RA; Doi, Y; Endimiani, A; Kasraian, S; Pires, J; Sendi, P; Taracila, M; Tinguely, R	1
Chang, CM; Chen, PL; Ko, WC; Lee, CC; Lee, NY; Li, CW; Li, MC	1
Abdile, AA; Doi, Y; Harris, PN; Huh, K; Huxley, RR; O'Neal, CS; Pandeya, N; Paterson, DL; Paynter, S; Shen, AW; Talbot, TR; Wei, JY	1
Cao, B; Chen, H; Chen, X; Chu, Y; Guo, P; Hu, B; Hu, Z; Jin, Y; Liao, K; Liu, W; Liu, Y; Luo, Y; Su, D; Tian, B; Wang, H; Wang, Y; Wang, Z; Xu, X; Zeng, J; Zhang, F; Zhang, R; Zhao, C; Zhou, C; Zhou, H; Zhuo, C; Zou, M	1
Berrio, I; Castro, B; Maldonado, N; Manjarrés, M; Robledo, C; Robledo, J	1
Estes, LL; Narayanan, PP; Patel, R; Rivera, CG	1
Higuchi, H; Horikoshi, Y; Isogai, M; Ito, K; Shoji, T; Suwa, J	1
Badal, RE; Biedenbach, DJ; Giao, PT; Hung Van, P; Phuong, DM; Su Minh Tuyet, N; Thi Thanh Nga, T; Vu Trung, N	1
Lavigne, JP; Meiller, E; Merens, A; Nicolas-Chanoine, MH; Pantel, A; Robert, J	1
Falagas, ME; Legakis, NJ; Skalidis, T; Vardakas, KZ	1
Falagas, ME; Kofteridis, DP; Maraki, S; Mavromanolaki, VE; Perdikis, D; Samonis, G; Vardakas, KZ	1
Hollenberg, SM; Khan, ZA	1
Fisher, K; Juang, P; Kollef, MH; Micek, ST; Trupka, T	1
Altshuler, J; Fedorenko, M; Kim, SA; Paris, D	1
Kim, JH; Kim, MJ; Kim, SB; Sohn, JW; Suh, JW; Yang, KS; Yoon, YK	1
Bland, CM; Chastain, DB; Cretella, DA; White, BP	1
Almirante, B; Escolà-Vergé, L; González-López, JJ; Larrosa, N; Len, O; Los-Arcos, I; Pigrau, C; Viñado, B	1
Cheok, SJH; Chew, KL; Heng, ST; Lye, DC; Ng, TM; Ng, WHW; Tambyah, PA; Tan, SH; Wan, S; Wu, JE; Yap, MY; Yong, J	1
Dang, B; Li, Z; Ma, S; Xu, Z; Zhang, H	1
Akazawa, M; Fukuda, H; Mimura, W	1
Chen, PL; Ko, WC; Lee, NY; Li, CW; Li, MC; Lo, CL; Syue, LS	1
Heo, BY; Jo, DY; Kwon, J; Lee, HJ; Lee, MW; Ryu, H; Song, IC; Yeon, SH; Yun, HJ	1
de La Blanchardière, A; Guérin, F; Le Hello, S; Meurant, A; Saint-Lorant, G	1
Bassetti, M; Giacobbe, DR	1
Carvalhaes, CG; Castanheria, M; Duncan, LR; Mendes, RE; Sader, HS	1
Mensa, J; Soriano, A	1
Maseda, E; Suárez de la Rica, A	1
Abdulhemid Said, L; Muhsin, EA; Sajid Al-Jubori, S	1
Hishinuma, T; Kirikae, T; Shimojima, M; Shintani, M; Suzuki, M; Tada, T; Tohya, M	1
Gill, CM; Nicolau, DP	2
Banaei, N; Bounthavong, M; Deresinski, S; Diep, C; Ha, D; Lu, B; Wong, M	1
Abdurahim, SA; Alameen, AA; Aloufi, AS; Elsayim, R; Eltayb, WA; Modafer, Y	1
Bercot, B; Bernier, J; Bleibtreu, A; Chaibi, K; Contejean, A; Cuzon, G; Delory, T; El Alaoui, F; Escaut, L; Joseph, A; Lafaurie, M; Maillard, A; Molina, JM; Paccoud, O; Poupet, H; Robert, J; Surgers, L; Tankovic, J; Villa, A	1
Chen, J; Jia, W; Jing, R; Li, J; Liu, Y; Sun, G; Sun, H; Wang, T; Xu, X; Xu, Y; Zhang, G	1
Boyer, P; Danion, F; Gravet, A; Hansmann, Y; Hoellinger, B; Kaeuffer, C; Lefebvre, N; Robert, A; Ruch, Y; Severac, F; Ursenbach, A	1
Asempa, TE; Fouad, A; Gill, CM; Nicolau, DP; Simner, PJ	1
Ávila-Núñez, M; Celestino, P; García-Formoso, L; Garrido-Ventín, M; Lima, O; Martinez-Lamas, L; Pérez-Landeiro, A; Pérez-Rodríguez, MT; Represa, M; Rubianes, M; Rubiñán, P; Sousa, A; Vasallo-Vidal, F	1
Bülow, L; Mecklenburg, M; Meng, Q; Song, C; Sun, X; Wang, Y; Wu, C; Xie, B	1

Reviews

6 review(s) available for carbapenems and cefepime

Article	Year
Empirical antibiotic monotherapy for febrile neutropenia: systematic review and meta-analysis of randomized controlled trials. The Journal of antimicrobial chemotherapy, 2006, Volume: 57, Issue:2 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Cefepime; Cephalosporins; Enzyme Inhibitors; Fever; Humans; Neutropenia; Penicillanic Acid; Penicillins; Quality Assurance, Health Care; Randomized Controlled Trials as Topic; Tazobactam; Treatment Outcome	2006
Carbapenems versus alternative antibiotics for the treatment of bloodstream infections caused by Enterobacter, Citrobacter or Serratia species: a systematic review with meta-analysis. The Journal of antimicrobial chemotherapy, 2016, Volume: 71, Issue:2 Topics: Anti-Bacterial Agents; Bacteremia; beta-Lactamase Inhibitors; Carbapenems; Cefepime; Cephalosporins; Enterobacteriaceae Infections; Humans; Quinolones; Serratia Infections; Survival Analysis; Treatment Outcome	2016
Valvular Heart Disease in Adults: Infective Endocarditis. FP essentials, 2017, Volume: 457 Topics: Anti-Bacterial Agents; Blood Culture; Carbapenems; Cefepime; Cephalosporins; Cross Infection; Echocardiography; Endocarditis; Endocarditis, Bacterial; Gentamicins; Heart Valve Prosthesis; Humans; Prosthesis-Related Infections; Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Vancomycin	2017
Is It Time to Rethink the Notion of Carbapenem-Sparing Therapy Against Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Bloodstream Infections? A Critical Review. The Annals of pharmacotherapy, 2018, Volume: 52, Issue:5 Topics: Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Carbapenems; Cefepime; Enterobacteriaceae; Enterobacteriaceae Infections; Fluoroquinolones; Humans	2018
Mechanism of action of cefiderocol. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2022, Volume: 35 Suppl 2 Topics: Animals; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cattle; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Gram-Negative Bacteria; Iron; Quinolones; Serine; Tetracyclines	2022
The role of cefiderocol in clinical practice. Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2022, Volume: 35 Suppl 2 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa	2022

Trials

4 trial(s) available for carbapenems and cefepime

Article	Year
Cefepime or carbapenem treatment for febrile neutropenia as a single agent is as effective as a combination of 4th-generation cephalosporin + aminoglycosides: comparative study. American journal of hematology, 2002, Volume: 71, Issue:4 Topics: Adult; Algorithms; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Drug Administration Schedule; Drug Therapy, Combination; Female; Fever; Humans; Leukemia; Lymphoma; Male; Neutropenia	2002
High-dose cefepime as an alternative treatment for infections caused by TEM-24 ESBL-producing Enterobacter aerogenes in severely-ill patients. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2006, Volume: 12, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Critical Illness; Cross Infection; Drug Therapy, Combination; Enterobacter aerogenes; Enterobacteriaceae Infections; Female; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Treatment Outcome	2006
Efficacy of intravenous ciprofloxacin in patients with febrile neutropenia refractory to initial therapy. Leukemia & lymphoma, 2006, Volume: 47, Issue:8 Topics: Adult; Aged; Algorithms; Carbapenems; Cefepime; Cephalosporins; Ciprofloxacin; Female; Fever; Hematologic Diseases; Humans; Male; Middle Aged; Neutropenia; Remission Induction; Salvage Therapy; Treatment Failure; Treatment Outcome	2006
Prospective randomized study of cefepime, panipenem, or meropenem monotherapy for patients with hematological disorders and febrile neutropenia. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2013, Volume: 19, Issue:1 Topics: Adolescent; Adult; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Female; Fever; Hematologic Diseases; Humans; Male; Meropenem; Neutropenia; Prospective Studies; Thienamycins; Treatment Outcome; Young Adult	2013

Other Studies

61 other study(ies) available for carbapenems and cefepime

Article	Year
[In vitro study of antibacterial activity of cefepime (Axepim) against gram negative bacteria: comparison with cephalosporins and other beta-lactams]. Pathologie-biologie, 1996, Volume: 44, Issue:2 Topics: Acinetobacter; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporinase; Cephalosporins; Drug Combinations; Drug Resistance, Microbial; Enterobacteriaceae; Hospital Units; In Vitro Techniques; Monobactams; Pseudomonas aeruginosa	1996
In-vitro activity of 21 beta-lactam antibiotics against penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae. The Journal of antimicrobial chemotherapy, 1998, Volume: 41, Issue:3 Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cefaclor; Cefadroxil; Cefatrizine; Cefepime; Cefixime; Cefotaxime; Cefpirome; Cefpodoxime; Ceftazidime; Ceftibuten; Ceftizoxime; Ceftriaxone; Cefuroxime; Cephalosporins; Cephradine; Drug Resistance, Microbial; Drug Resistance, Multiple; Humans; Microbial Sensitivity Tests; Penicillin Resistance; Penicillins; Piperacillin; Pneumococcal Infections; Serotyping; Species Specificity; Streptococcus pneumoniae	1998
Efficacies of imipenem, meropenem, cefepime, and ceftazidime in rats with experimental pneumonia due to a carbapenem-hydrolyzing beta-lactamase-producing strain of Enterobacter cloacae. Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:4 Topics: Animals; Anti-Bacterial Agents; Area Under Curve; beta-Lactamases; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Creatinine; Drug Resistance, Microbial; Enterobacter cloacae; Enterobacteriaceae Infections; Half-Life; Imipenem; Kidney Diseases; Male; Meropenem; Penicillinase; Pneumonia, Bacterial; Protein Binding; Rats; Rats, Wistar; Thienamycins; Uranyl Nitrate	2000
Comparative in vitro bactericidal activity between cefepime and ceftazidime, alone and associated with amikacin, against carbapenem-resistant Pseudomonas aeruginosa strains. Diagnostic microbiology and infectious disease, 2000, Volume: 37, Issue:1 Topics: Amikacin; Anti-Bacterial Agents; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Drug Resistance, Microbial; Microbial Sensitivity Tests; Pseudomonas aeruginosa	2000
In vitro activity of meropenem, imipenem, cefepime and ceftazidime against Pseudomonas aeruginosa isolates from cystic fibrosis patients. The Journal of antimicrobial chemotherapy, 2000, Volume: 45, Issue:6 Topics: Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Cystic Fibrosis; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Thienamycins	2000
Comparative in vitro antimicrobial activity of a new carbapenem, E1010, and tentative disc diffusion test interpretative criteria. The Journal of antimicrobial chemotherapy, 2001, Volume: 48, Issue:1 Topics: Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Diffusion; Enterobacteriaceae; Imipenem; Meropenem; Microbial Sensitivity Tests; Pyrrolidines; Thienamycins	2001
[Antimicrobial activities of carbapenems and fourth generation cephems against clinically isolated strains]. The Japanese journal of antibiotics, 2001, Volume: 54, Issue:9 Topics: Bacteria; Carbapenems; Cefepime; Cefozopran; Cephalosporins; Imipenem; Meropenem; Thienamycins	2001
Sustained activity and spectrum of selected extended-spectrum beta-lactams (carbapenems and cefepime) against Enterobacter spp. and ESBL-producing Klebsiella spp.: report from the SENTRY antimicrobial surveillance program (USA, 1997-2000). International journal of antimicrobial agents, 2003, Volume: 21, Issue:1 Topics: beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Enterobacter; Klebsiella; Microbial Sensitivity Tests	2003
Retrospective study of clinical outcomes with extended-spectrum beta-lactamases--a different interpretation. Pharmacotherapy, 2004, Volume: 24, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Infections; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Humans; Retrospective Studies; Time Factors; Treatment Outcome	2004
Activity of cefepime and carbapenems in experimental pneumonia caused by porin-deficient Klebsiella pneumoniae producing FOX-5 beta-lactamase. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2005, Volume: 11, Issue:1 Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Colony Count, Microbial; Guinea Pigs; Humans; Imipenem; Klebsiella Infections; Klebsiella pneumoniae; Lung; Meropenem; Microbial Sensitivity Tests; Pneumonia, Bacterial; Porins; Thienamycins; Treatment Outcome	2005
In vivo selection of Enterobacter aerogenes with reduced susceptibility to cefepime and carbapenems associated with decreased expression of a 40 kDa outer membrane protein and hyperproduction of AmpC beta-lactamase. International journal of antimicrobial agents, 2006, Volume: 27, Issue:6 Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; Base Sequence; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Enterobacter aerogenes; Humans; Microbial Sensitivity Tests; Molecular Sequence Data	2006
Clinical experiences of the infections caused by extended-spectrum beta-lactamase-producing Serratia marcescens at a medical center in Taiwan. Japanese journal of infectious diseases, 2006, Volume: 59, Issue:3 Topics: Amikacin; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Electrophoresis, Gel, Pulsed-Field; Humans; Imipenem; Microbial Sensitivity Tests; Molecular Epidemiology; Molecular Sequence Data; Polymerase Chain Reaction; Serratia Infections; Serratia marcescens; Taiwan	2006
In vitro activity of cefepime combined with sulbactam against clinical isolates of carbapenem-resistant Acinetobacter spp. International journal of antimicrobial agents, 2006, Volume: 28, Issue:5 Topics: Acinetobacter; Acinetobacter baumannii; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Synergism; Humans; Microbial Sensitivity Tests; Sulbactam	2006
Carbapenem-resistant Acinetobacter baumannii: an emerging threat for patients with post-neurosurgical meningitis. International journal of antimicrobial agents, 2007, Volume: 29, Issue:1 Topics: Acinetobacter baumannii; Adolescent; Adult; Aged; Amikacin; Anti-Bacterial Agents; Carbapenems; Cefepime; Cefoperazone; Cephalosporins; Ciprofloxacin; Drug Resistance, Bacterial; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Imipenem; Male; Meningitis, Bacterial; Meropenem; Microbial Sensitivity Tests; Middle Aged; Neurosurgical Procedures; Postoperative Complications; Thienamycins; Turkey	2007
Restoration of susceptibility of intracellular methicillin-resistant Staphylococcus aureus to beta-lactams: comparison of strains, cells, and antibiotics. Antimicrobial agents and chemotherapy, 2008, Volume: 52, Issue:8 Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Cefepime; Cefuroxime; Cell Line; Cells, Cultured; Cephalosporins; Cloxacillin; Humans; Hydrogen-Ion Concentration; Imipenem; Meropenem; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Oxacillin; Phagocytosis; Staphylococcus aureus; Thienamycins	2008
Prolonged bacteraemia caused by VIM-1 metallo-beta-lactamase-producing Proteus mirabilis: first report from Italy. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2010, Volume: 16, Issue:2 Topics: Aged; Amikacin; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Chromosomes, Bacterial; DNA, Bacterial; Humans; Integrons; Italy; Male; Meropenem; Plasmids; Proteus Infections; Proteus mirabilis; Surgical Wound Infection; Thienamycins; Treatment Failure; Treatment Outcome	2010
Empiric combination antibiotic therapy is associated with improved outcome against sepsis due to Gram-negative bacteria: a retrospective analysis. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:5 Topics: Acinetobacter Infections; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Cohort Studies; Drug Therapy, Combination; Escherichia coli Infections; Female; Fluoroquinolones; Gram-Negative Bacterial Infections; Hospital Mortality; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Retrospective Studies; Sepsis; Shock, Septic	2010
Activity of ACHN-490 tested alone and in combination with other agents against Pseudomonas aeruginosa. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Doripenem; Imipenem; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa	2011
Overexpression of AmpC and efflux pumps in Pseudomonas aeruginosa isolates from bloodstream infections: prevalence and impact on resistance in a Spanish multicenter study. Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:5 Topics: Anti-Bacterial Agents; Bacterial Outer Membrane Proteins; Bacterial Proteins; beta-Lactamases; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Imipenem; Membrane Transport Proteins; Meropenem; Microbial Sensitivity Tests; Porins; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction; Thienamycins	2011
[Actual aspects of sepsis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2011, Volume: 56, Issue:3-4 Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Hospitals; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Retrospective Studies; Russia; Sepsis; Vancomycin	2011
Efficacy of doripenem against Escherichia coli and Klebsiella pneumoniae in experimental meningitis. The Journal of antimicrobial chemotherapy, 2012, Volume: 67, Issue:3 Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Carbapenems; Cefepime; Cephalosporins; Disease Models, Animal; Doripenem; Escherichia coli; Escherichia coli Infections; Klebsiella Infections; Klebsiella pneumoniae; Meningitis, Bacterial; Rabbits; Treatment Outcome	2012
Cefepime therapy for monomicrobial bacteremia caused by cefepime-susceptible extended-spectrum beta-lactamase-producing Enterobacteriaceae: MIC matters. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2013, Volume: 56, Issue:4 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Carbapenems; Case-Control Studies; Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Treatment Outcome	2013
Risk factors and mortality of patients with nosocomial carbapenem-resistant Acinetobacter baumannii pneumonia. American journal of infection control, 2013, Volume: 41, Issue:7 Topics: Acinetobacter baumannii; Acinetobacter Infections; Aged; Anti-Bacterial Agents; beta-Lactam Resistance; Carbapenems; Cefepime; Cephalosporins; Cohort Studies; Cross Infection; Disease Susceptibility; Drug Resistance, Multiple, Bacterial; Female; Humans; Male; Middle Aged; Outcome Assessment, Health Care; Pneumonia; Retrospective Studies; Risk Factors	2013
When pharmacodynamics trump costs: an antimicrobial stewardship program's approach to selecting optimal antimicrobial agents. Clinical therapeutics, 2013, Volume: 35, Issue:6 Topics: Adult; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Doripenem; Drug Costs; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Monte Carlo Method; Pseudomonas aeruginosa; Pseudomonas Infections; Thienamycins	2013
Cefepime vs other antibacterial agents for the treatment of Enterobacter species bacteremia. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2014, Volume: 58, Issue:11 Topics: Aged; Anti-Bacterial Agents; Bacteremia; Carbapenems; Cefepime; Cephalosporins; Enterobacter; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Survival Analysis; Treatment Outcome	2014
[Mechanism of drug resistance of carbapenems-resistant Acinetobacter baumannii and the application of a combination of drugs in vitro]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns, 2014, Volume: 30, Issue:2 Topics: Acinetobacter baumannii; Acinetobacter Infections; Ampicillin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Carbapenems; Cefepime; Cephalosporins; Drug Resistance; Humans; In Vitro Techniques; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Pharmaceutical Preparations; Piperacillin; Piperacillin, Tazobactam Drug Combination; Sulbactam; Thienamycins	2014
Characterization of resistance genes in 68 ESBL-producing Klebsiella pneumonia in Lebanon. Medecine et maladies infectieuses, 2014, Volume: 44, Issue:11-12 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Colony Count, Microbial; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Klebsiella Infections; Klebsiella pneumoniae; Lebanon; Microbial Sensitivity Tests; Organ Specificity; Substrate Specificity	2014
In Vivo Evolution of CMY-2 to CMY-33 β-Lactamase in Escherichia coli Sequence Type 131: Characterization of an Acquired Extended-Spectrum AmpC Conferring Resistance to Cefepime. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:12 Topics: Aged; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Cefepime; Ceftriaxone; Cephalosporins; Drug Resistance, Multiple, Bacterial; Escherichia coli; Escherichia coli Infections; Escherichia coli Proteins; Humans; Male; Microbial Sensitivity Tests; Molecular Docking Simulation	2015
Cefepime Therapy for Monomicrobial Enterobacter cloacae Bacteremia: Unfavorable Outcomes in Patients Infected by Cefepime-Susceptible Dose-Dependent Isolates. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:12 Topics: Aged; Anti-Bacterial Agents; Bacteremia; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Diabetes Complications; Diabetes Mellitus; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Gene Expression; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Neoplasms; Renal Insufficiency, Chronic; Retrospective Studies; Severity of Illness Index; Survival Analysis; Treatment Outcome	2015
[Analysis of pathogen spectrum and resistance of clinical common organisms causing bloodstream infections, hospital-acquired pneumonia and intra-abdominal infections from thirteen teaching hospitals in 2013]. Zhonghua yi xue za zhi, 2015, Jun-09, Volume: 95, Issue:22 Topics: Anti-Bacterial Agents; Bacteremia; Carbapenems; Cefepime; Cephalosporins; China; Cross Infection; Hospitals, Teaching; Humans; Intraabdominal Infections; Microbial Sensitivity Tests; Minocycline; Pneumonia; Tigecycline; Vancomycin	2015
Ertapenem resistance in 2 tertiary-care hospitals: Microbiology, epidemiology, and risk factors. Enfermedades infecciosas y microbiologia clinica, 2017, Volume: 35, Issue:8 Topics: Aged; Antimicrobial Stewardship; beta-Lactam Resistance; Carbapenems; Case-Control Studies; Cefepime; Colombia; Cross Infection; Diagnosis-Related Groups; Enterobacteriaceae; Enterobacteriaceae Infections; Ertapenem; Female; Humans; Logistic Models; Male; Middle Aged; Retrospective Studies; Risk Factors; Tertiary Care Centers	2017
Impact of Cefepime Susceptible-Dose-Dependent MIC for Enterobacteriaceae on Reporting and Prescribing. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:6 Topics: Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Drug Prescriptions; Enterobacteriaceae; Enterobacteriaceae Infections; Humans; Microbial Sensitivity Tests	2016
Impact of computerized pre-authorization of broad spectrum antibiotics in Pseudomonas aeruginosa at a children's hospital in Japan. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2016, Volume: 22, Issue:8 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Hospitals; Humans; Japan; Microbial Sensitivity Tests; Penicillanic Acid; Piperacillin; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Pseudomonas Infections; Tokyo	2016
Antimicrobial-resistant Pseudomonas aeruginosa and Acinetobacter baumannii From Patients With Hospital-acquired or Ventilator-associated Pneumonia in Vietnam. Clinical therapeutics, 2016, Volume: 38, Issue:9 Topics: Acinetobacter baumannii; Amikacin; Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Cross Infection; Doripenem; Drug Resistance, Multiple, Bacterial; Fluoroquinolones; Gentamicins; Humans; Longitudinal Studies; Microbial Sensitivity Tests; Minocycline; Pneumonia, Bacterial; Pneumonia, Ventilator-Associated; Pseudomonas aeruginosa; Tigecycline; Vietnam	2016
Development of an algorithm for phenotypic screening of carbapenemase-producing Enterobacteriaceae in the routine laboratory. BMC infectious diseases, 2017, 01-17, Volume: 17, Issue:1 Topics: Algorithms; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Clavulanic Acids; Drug Resistance, Bacterial; Enterobacteriaceae; Ertapenem; Humans; Imipenem; Meropenem; Microbial Sensitivity Tests; Penicillanic Acid; Penicillins; Tazobactam; Thienamycins; Ticarcillin	2017
Activity of cefiderocol (S-649266) against carbapenem-resistant Gram-negative bacteria collected from inpatients in Greek hospitals. The Journal of antimicrobial chemotherapy, 2017, 06-01, Volume: 72, Issue:6 Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactam Resistance; beta-Lactamases; Carbapenems; Cefepime; Cefiderocol; Ceftazidime; Cephalosporins; Colistin; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Greece; Humans; Inpatients; Klebsiella pneumoniae; Meropenem; Microbial Sensitivity Tests; Minocycline; Pseudomonas aeruginosa; Thienamycins; Tigecycline	2017
In vitro susceptibility and resistance phenotypes in contemporary Enterobacter isolates in a university hospital in Crete, Greece. Future microbiology, 2017, Volume: 12 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Child; Colistin; Drug Resistance, Multiple, Bacterial; Enterobacter; Enterobacteriaceae Infections; Greece; Hospitals, University; Humans; Microbial Sensitivity Tests; Minocycline; Penicillanic Acid; Phenotype; Piperacillin; Piperacillin, Tazobactam Drug Combination; Tigecycline	2017
Enhanced antimicrobial de-escalation for pneumonia in mechanically ventilated patients: a cross-over study. Critical care (London, England), 2017, 07-15, Volume: 21, Issue:1 Topics: Academic Medical Centers; Aged; Anti-Bacterial Agents; Carbapenems; Cefepime; Ceftriaxone; Cephalosporins; Cross-Over Studies; Female; Hospital Mortality; Humans; Intensive Care Units; Male; Middle Aged; Monobactams; Pneumonia; Pneumonia, Ventilator-Associated; Prospective Studies; Quinolones; Respiration, Artificial; Statistics, Nonparametric	2017
Cefepime versus carbapenems for the treatment of urinary tract infections caused by extended-spectrum β-lactamase-producing enterobacteriaceae. International journal of antimicrobial agents, 2018, Volume: 51, Issue:1 Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Microbial Sensitivity Tests; Retrospective Studies; Urinary Tract Infections	2018
The use of cefepime as a carbapenem-sparing antibiotic for treating uncomplicated acute pyelonephritis caused by extended-spectrum β-lactamase producing Escherichia coli. Infectious diseases (London, England), 2018, Volume: 50, Issue:3 Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Carbapenems; Cefepime; Cephalosporins; Ertapenem; Escherichia coli; Escherichia coli Infections; Female; Hospitals, University; Humans; Male; Middle Aged; Pyelonephritis; Republic of Korea; Retrospective Studies; Risk Factors; Treatment Outcome	2018
Infections by OXA-48-like-producing Klebsiella pneumoniae non-co-producing extended-spectrum beta-lactamase: Can they be successfully treated with cephalosporins? Journal of global antimicrobial resistance, 2019, Volume: 19 Topics: Aged; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Ceftriaxone; Cephalosporins; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Middle Aged; Nephritis; Retrospective Studies; Spain	2019
Outcomes of treating AmpC-producing Enterobacterales bacteraemia with carbapenems vs. non-carbapenems. International journal of antimicrobial agents, 2020, Volume: 55, Issue:2 Topics: Aged; Anti-Bacterial Agents; Bacteremia; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cefepime; Enterobacteriaceae; Enterobacteriaceae Infections; Female; Humans; Male; Middle Aged; Piperacillin, Tazobactam Drug Combination; Retrospective Studies	2020
Coexistence of the bla Scientific reports, 2020, 02-11, Volume: 10, Issue:1 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Cefepime; Drug Resistance, Bacterial; Enterobacteriaceae; Genome, Bacterial; Rivers; Streptomycin	2020
Antimicrobial utilization and antimicrobial resistance in patients with haematological malignancies in Japan: a multi-centre cross-sectional study. Annals of clinical microbiology and antimicrobials, 2020, Feb-17, Volume: 19, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Carbapenems; Cefepime; Cross-Sectional Studies; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Escherichia coli; Female; Hematologic Neoplasms; Humans; Japan; Male; Middle Aged; Piperacillin, Tazobactam Drug Combination; Young Adult	2020
Clinical impact of cefepime breakpoint in patients with carbapenem-resistant Klebsiella pneumoniae bacteraemia. International journal of antimicrobial agents, 2021, Volume: 57, Issue:2 Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Bacterial Proteins; beta-Lactamases; Carbapenem-Resistant Enterobacteriaceae; Carbapenems; Cefepime; Drug Therapy, Combination; Female; Humans; Klebsiella Infections; Klebsiella pneumoniae; Male; Microbial Sensitivity Tests; Middle Aged	2021
Impact of pre-transplant use of antibiotics on the graft-versus-host disease in adult patients with hematological malignancies. Hematology (Amsterdam, Netherlands), 2021, Volume: 26, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Carbapenems; Cefepime; Disease-Free Survival; Female; Glycopeptides; Graft vs Host Disease; Hematologic Neoplasms; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppressive Agents; Male; Methotrexate; Middle Aged; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Transplantation, Homologous; Treatment Outcome; Young Adult	2021
Cefepime use: A need for antimicrobial stewardship. Infectious diseases now, 2021, Volume: 51, Issue:5 Topics: Anti-Bacterial Agents; Antimicrobial Stewardship; Carbapenems; Cefepime; Humans; Retrospective Studies	2021
Innovative β-lactam/β-lactamase inhibitor combinations for carbapenem-resistant Gram-negative bacteria. Future microbiology, 2022, Volume: 17 Topics: Anti-Bacterial Agents; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Cefepime; Drug Combinations; Gram-Negative Bacteria; Lactams; Microbial Sensitivity Tests	2022
Antimicrobial activity of cefepime/zidebactam (WCK 5222), a β-lactam/β-lactam enhancer combination, against clinical isolates of Gram-negative bacteria collected worldwide (2018-19). The Journal of antimicrobial chemotherapy, 2022, 09-30, Volume: 77, Issue:10 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Cyclooctanes; Enterobacteriaceae; Gram-Negative Bacteria; Hydrazines; Lactams; Microbial Sensitivity Tests; Piperidines; Pseudomonas aeruginosa; Tazobactam	2022
Prevalence of Efflux Pump and Porin-Related Antimicrobial Resistance in Clinical Archives of Razi Institute, 2022, Volume: 77, Issue:2 Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Cefazolin; Cefepime; Cefoxitin; Ceftazidime; Ceftriaxone; Cephalosporins; Drug Resistance, Bacterial; Ertapenem; Humans; Imipenem; Iraq; Klebsiella pneumoniae; Microbial Sensitivity Tests; Porins; Prevalence	2022
Plasmids Harboring a Tandem Duplicate of Microbial drug resistance (Larchmont, N.Y.), 2023, Volume: 29, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Humans; Japan; Microbial Sensitivity Tests; Plasmids; Pseudomonas aeruginosa; Pseudomonas Infections	2023
Phenotypic and genotypic profile of ceftolozane/tazobactam-non-susceptible, carbapenem-resistant Pseudomonas aeruginosa. The Journal of antimicrobial chemotherapy, 2022, 12-23, Volume: 78, Issue:1 Topics: Anti-Bacterial Agents; Azabicyclo Compounds; beta-Lactamases; Carbapenems; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Tazobactam	2022
Carbapenem-resistant Pseudomonas aeruginosa: an assessment of frequency of isolation from ICU versus non-ICU, phenotypic and genotypic profiles in a multinational population of hospitalized patients. Antimicrobial resistance and infection control, 2022, 11-30, Volume: 11, Issue:1 Topics: Carbapenems; Cefepime; Ceftazidime; Phenotype; Pseudomonas aeruginosa; Tazobactam	2022
Piperacillin/tazobactam versus cefepime or carbapenems for cefoxitin-non-susceptible Enterobacter cloacae, Klebsiella aerogenes, Citrobacter freundii, Serratia marcescens and Morganella morganii bacteraemia in immunocompromised patients. The Journal of antimicrobial chemotherapy, 2023, 04-03, Volume: 78, Issue:4 Topics: Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Carbapenems; Cefepime; Cefoxitin; Citrobacter freundii; Enterobacter aerogenes; Enterobacter cloacae; Humans; Microbial Sensitivity Tests; Morganella morganii; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Serratia marcescens	2023
Molecular Dynamic Analysis of Carbapenem-Resistant Molecules (Basel, Switzerland), 2023, Mar-09, Volume: 28, Issue:6 Topics: Anti-Bacterial Agents; Carbapenems; Cefepime; Humans; Imipenem; Klebsiella; Klebsiella pneumoniae; Ligands; Meropenem; Metal Nanoparticles; Microbial Sensitivity Tests; Molecular Dynamics Simulation; Monobactams; Nanoparticles; Pneumonia; Porins; Spectroscopy, Fourier Transform Infrared; Zinc Oxide	2023
Effectiveness of third-generation cephalosporins or piperacillin compared with cefepime or carbapenems for severe infections caused by wild-type AmpC β-lactamase-producing Enterobacterales: A multi-centre retrospective propensity-weighted study. International journal of antimicrobial agents, 2023, Volume: 62, Issue:1 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Cephalosporins; Humans; Piperacillin; Piperacillin, Tazobactam Drug Combination; Retrospective Studies	2023
Microbiology spectrum, 2023, 06-15, Volume: 11, Issue:3 Topics: Anti-Bacterial Agents; Aztreonam; beta-Lactamases; Carbapenems; Cefepime; Microbial Sensitivity Tests; Tigecycline	2023
Cefepime vs carbapenems for treating third-generation cephalosporin-resistant AmpC β-lactamase-hyperproducing Enterobacterales bloodstream infections: a multicenter retrospective study. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2023, Volume: 134 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Enterobacteriaceae; Enterobacteriaceae Infections; Gammaproteobacteria; Humans; Microbial Sensitivity Tests; Retrospective Studies; Sepsis	2023
Cefepime in vivo activity against carbapenem-resistant Enterobacterales that test as cefepime susceptible or susceptible-dose dependent in vitro: implications for clinical microbiology laboratory and clinicians. The Journal of antimicrobial chemotherapy, 2023, 09-05, Volume: 78, Issue:9 Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefepime; Enterobacteriaceae; Gammaproteobacteria; Humans; Mice; Microbial Sensitivity Tests	2023
Carbapenem alternatives for treatment of bloodstream infections due to AmpC producing enterobacterales. Annals of clinical microbiology and antimicrobials, 2023, Aug-17, Volume: 22, Issue:1 Topics: Adult; Aged; Bacteremia; Carbapenems; Cefepime; Humans; Piperacillin, Tazobactam Drug Combination; Retrospective Studies; Sepsis	2023
Activity fingerprinting of AMR β-lactamase towards a fast and accurate diagnosis. Frontiers in cellular and infection microbiology, 2023, Volume: 13 Topics: Anti-Bacterial Agents; beta-Lactamases; Carbapenems; Cefazolin; Cefepime; Humans	2023