Compounds > carbapenems
Page last updated: 2024-09-04

carbapenems and captopril

carbapenems has been researched along with captopril in 5 studies

Compound Research Comparison

Studies
(carbapenems)		Trials
(carbapenems)		Recent Studies (post-2010)
(carbapenems)		Studies
(captopril)		Trials
(captopril)		Recent Studies (post-2010) (captopril)
7,3551475,27710,3201,514890

Protein Interaction Comparison

ProteinTaxonomycarbapenems (IC50)captopril (IC50)
Leukotriene A-4 hydrolaseHomo sapiens (human)3.6
Angiotensin-converting enzyme Homo sapiens (human)0.084
Angiotensin-converting enzymeOryctolagus cuniculus (rabbit)0.0173
Succinyl-diaminopimelate desuccinylaseHaemophilus influenzae Rd KW203.3
Angiotensin-converting enzymeRattus norvegicus (Norway rat)0.1004
Beta-lactamase Pseudomonas aeruginosa5
Angiotensin-converting enzyme 2 Homo sapiens (human)0.011
Beta-lactamase class B VIM-2 Pseudomonas aeruginosa3.5

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Iguchi, M; Kato, K; Kikuchi, A; Kuraoka, E; Kurosawa, T; Shibasaki, S; Shirasaka, Y; Suzuki, H; Tamai, I1
Brem, J; Gileadi, O; Lee, SY; McDonough, MA; McHugh, PJ; Schofield, CJ; van Berkel, SS; Walsh, TR; Zollman, D1
Arakawa, Y; Jin, W; Kimura, K; Kurosaki, H; Mori, S; Wachino, J; Yamaguchi, Y1
Akhter, S; Bayer, A; Christopeit, T; Leiros, HS; Samuelsen, Ø; Skagseth, S1
Do, TG; Huynh, PNH; Nguyen, DN; Nguyen, TT; Thai, KM; Tran, VH; Tran, VT; Vo, TP1

Other Studies

5 other study(ies) available for carbapenems and captopril

ArticleYear
Intestinal absorption mechanism of tebipenem pivoxil, a novel oral carbapenem: involvement of human OATP family in apical membrane transport.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Biological Transport, Active; Caco-2 Cells; Captopril; Carbapenems; Female; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Kinetics; Male; Oocytes; Organic Anion Transporters; Peptide Transporter 1; Rats; Rats, Sprague-Dawley; Symporters; Xenopus

2010
Structural Basis of Metallo-β-Lactamase Inhibition by Captopril Stereoisomers.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Captopril; Carbapenems; Cloning, Molecular; Crystallography, X-Ray; Drug Repositioning; Enterobacteriaceae; Gene Expression; Hydrolysis; Kinetics; Microbial Sensitivity Tests; Models, Molecular; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship

2016
Structural Insights into Recognition of Hydrolyzed Carbapenems and Inhibitors by Subclass B3 Metallo-β-Lactamase SMB-1.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents; beta-Lactamases; Captopril; Carbapenems; Catalytic Domain; Crystallography, X-Ray; Doripenem; Imipenem; Meropenem; Mesna; Protein Structure, Secondary; Protein Structure, Tertiary; Serratia marcescens; Thienamycins

2016
Structural Insights into TMB-1 and the Role of Residues 119 and 228 in Substrate and Inhibitor Binding.
    Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:8

    Topics: Achromobacter denitrificans; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; Captopril; Carbapenems; Microbial Sensitivity Tests; Surface Plasmon Resonance

2017
The Effects of One-Point Mutation on the New Delhi Metallo Beta-Lactamase-1 Resistance toward Carbapenem Antibiotics and β-Lactamase Inhibitors: An In Silico Systematic Approach.
    International journal of molecular sciences, 2022, Dec-16, Volume: 23, Issue:24

    Topics: Anti-Bacterial Agents; Bacteria; beta-Lactamase Inhibitors; beta-Lactamases; Captopril; Carbapenems; Microbial Sensitivity Tests; Point Mutation; Thiorphan

2022