Compounds > carbapenems
Page last updated: 2024-09-04

carbapenems and aspartic acid

carbapenems has been researched along with aspartic acid in 7 studies

Compound Research Comparison

Studies
(carbapenems)		Trials
(carbapenems)		Recent Studies (post-2010)
(carbapenems)		Studies
(aspartic acid)		Trials
(aspartic acid)		Recent Studies (post-2010) (aspartic acid)
7,3551475,27723,0054174,018

Protein Interaction Comparison

ProteinTaxonomycarbapenems (IC50)aspartic acid (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.638
Excitatory amino acid transporter 1Homo sapiens (human)90.1265
Excitatory amino acid transporter 2Homo sapiens (human)11
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)1.638
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)1.638
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)1.638
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)1.638
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)1.638
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)1.638

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's4 (57.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakae, T; Ono, T; Yoneyama, H; Yoshihara, E1
Kondo, K; Seki, M; Yamanaka, T1
Guo, H; Xie, D; Xu, D1
Chen, L; Clancy, CJ; Hao, B; Kreiswirth, BN; Nguyen, MH; Perlin, DS; Shields, RK1
Courvalin, P; Meziane-Cherif, D1
Coombes, BK; De Pascale, G; King, AM; King, DT; Reid-Yu, SA; Strynadka, NC; Walsh, TR; Wang, W; Wright, GD1
Schiffer, G; von Nussbaum, F1

Other Studies

7 other study(ies) available for carbapenems and aspartic acid

ArticleYear
Identification of the catalytic triad of the protein D2 protease in Pseudomonas aeruginosa.
    Biochemical and biophysical research communications, 1998, Jun-09, Volume: 247, Issue:1

    Topics: Alanine; Amino Acid Substitution; Asparagine; Aspartic Acid; Carbapenems; Catalysis; Endopeptidases; Glutamine; Histidine; Imipenem; Ion Channels; Microbial Sensitivity Tests; Mutagenesis, Site-Directed; Porins; Pseudomonas aeruginosa; Serine

1998
Practical synthesis of (R)-4-mercaptopyrrolidine-2-thione from L-aspartic acid. Preparation of a novel orally active 1-beta-methylcarbapenem, TA-949.
    The Journal of organic chemistry, 2000, Jan-28, Volume: 65, Issue:2

    Topics: Administration, Oral; Anti-Bacterial Agents; Aspartic Acid; Carbapenems; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrrolidines; Spectrophotometry, Infrared; Thiones

2000
Catalytic mechanism of class B2 metallo-beta-lactamase.
    The Journal of biological chemistry, 2006, Mar-31, Volume: 281, Issue:13

    Topics: Aeromonas hydrophila; Aspartic Acid; Bacterial Proteins; beta-Lactamases; Binding Sites; Carbapenems; Catalysis; Hydrolysis; Ligands; Models, Chemical; Models, Molecular; Models, Theoretical; Protein Binding; Protein Conformation; Protons; Quantum Theory; Thermodynamics; Thienamycins; Water; Zinc

2006
Doripenem, gentamicin, and colistin, alone and in combinations, against gentamicin-susceptible, KPC-producing Klebsiella pneumoniae strains with various ompK36 genotypes.
    Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:6

    Topics: Algorithms; Anti-Bacterial Agents; Aspartic Acid; Bacterial Proteins; beta-Lactamases; Carbapenems; Colistin; Doripenem; Drug Therapy, Combination; Genotype; Gentamicins; Glycine; Klebsiella pneumoniae; Microbial Sensitivity Tests; Mutagenesis, Insertional; Porins

2014
Antibiotic resistance: to the rescue of old drugs.
    Nature, 2014, Jun-26, Volume: 510, Issue:7506

    Topics: Animals; Aspartic Acid; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Carbapenems; Female; Gram-Negative Bacteria; Meropenem; Thienamycins

2014
Aspergillomarasmine A overcomes metallo-β-lactamase antibiotic resistance.
    Nature, 2014, Jun-26, Volume: 510, Issue:7506

    Topics: Animals; Anti-Bacterial Agents; Aspartic Acid; Aspergillus; beta-Lactam Resistance; beta-Lactamase Inhibitors; beta-Lactamases; Biological Products; Carbapenems; Drug Evaluation, Preclinical; Drug Synergism; Female; Gram-Negative Bacteria; Klebsiella pneumoniae; Meropenem; Mice; Thienamycins

2014
Aspergillomarasmine A, an inhibitor of bacterial metallo-β-lactamases conferring blaNDM and blaVIM resistance.
    Angewandte Chemie (International ed. in English), 2014, Oct-27, Volume: 53, Issue:44

    Topics: Animals; Aspartic Acid; beta-Lactam Resistance; beta-Lactamase Inhibitors; Carbapenems; Female; Gram-Negative Bacteria; Thienamycins

2014