carbamazepine and rifampin

carbamazepine has been researched along with rifampin in 54 studies

Research

Studies (54)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (11.11)	18.7374
1990's	5 (9.26)	18.2507
2000's	11 (20.37)	29.6817
2010's	27 (50.00)	24.3611
2020's	5 (9.26)	2.80

Authors

Authors	Studies
Strassburg, CP; Tukey, RH	1
Burk, O; Eichelbaum, M; Geick, A	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Erdmann, F; Fischer, G; Harris, R; Hopkins, S; Huang, Z; Murray, MG; Ribeill, Y; Scorneaux, B; Smitley, C; Wring, S	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chang, G; Di, L; Huang, Y; Lin, Z; Liston, TE; Scott, DO; Troutman, MD; Umland, JP	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Dickmann, LJ; Isoherranen, N	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Artursson, P; Mateus, A; Matsson, P	1
Bharate, SS; Vishwakarma, RA	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Artsimovitch, I; Chan, ST; Chu, AJ; Harper, R; Lin, L; Ma, C; Xiao, M; Yang, X; Ye, J; Zuo, Z	1
Johnson, J	1
Denning, DW; Graybill, JR; Hanson, LH; Pappagianis, D; Rinaldi, MG; Sharkey, PK; Stevens, DA; Tucker, RM	1
Debreczeni, LA; Herjavecz, I; Szeitz, A	1
Brodie, MJ; Rapeport, WG	1
Gairí Tahull, JM; Poo Argüelles, P; Samarra Riera, JM; Vernet Bori, A	1
Kelderman, CS; van der Grient, AJ	1
Greim, H	1
Bachmann, KA; Jauregui, L	1
Hirata, M; Nishibe, Y	1
Hirayama, F; Iizumi, Y; Kawasaki, T; Koshio, H; Matsumoto, Y; Sato, K; Taniuchi, Y	1
Gibson, GG; Goldfarb, PS; Gray, TJ; Ogg, MS; Tarbit, M; Williams, JM	1
Chiba, K; Horikawa, M; Kato, M; Sugiyama, Y	1
de Morais, SM; Fahmi, OA; Liras, JL; Maurer, TS; Mills, JB; Ripp, SL; Trevena, KA	1
Goldring, C; Morgan, P; Owen, A; Park, BK; Pirmohamed, M	1
Hangaishi, A; Kurokawa, M	1
Aso, Y; Kaneko, A; Kato, M; Mitsui, T; Sekiguchi, N; Takeda, K	1
Rodrigues, AD; Yang, Z	1
Aoyama, E; Kamiguchi, N; Moriwaki, T; Okuda, T	1
Hayashi, M; Shou, M; Skiles, GL; Xu, Y; Zhou, Y	1
Hanrath, MA; Swart, EL	1
Hsu, V; Pan, Y; Sinha, V; Wagner, C; Zhao, P	1
Kullak-Ublick, GA; Sigaroudi, A; Weiler, S	1
Almond, LM; Gardner, I; Hatley, O; Jamei, M; Kenny, JR; Mukadam, S; Okialda, K; Rostami-Hodjegan, A; Rowland-Yeo, K; Tay, S; Wong, S	1
De Jong, J; de Zwart, L; Mannaert, E; Monshouwer, M; Snoeys, J; Sukbuntherng, J	1
Kearney, BP; Kirby, BJ; Ling, J; Lutz, JD; Massetto, B; Mathias, A; Song, Q; Wang, L; Worth, A	1
Bruckmueller, H; Brueck, S; Busch, D; Cascorbi, I; Martin, P; Oswald, S; Siegmund, W; Wegner, D	1
Chaturvedula, A; Cicali, B; Cristofoletti, R; Hoechel, J; Lingineni, K; Schmidt, S; Vozmediano, V; Wendl, T; Wiesinger, H	1
Douxfils, J; Hainaut, P; Hardy, M; Larock, AS; Lessire, S; Mullier, F; Sennesael, AL; Spinewine, A	1
Alves, G; Falcão, A; Fortuna, A; Meirinho, S; Rodrigues, M	1
Akpan, A; Bearon, R; Grañana-Castillo, S; Hodge, D; Khoo, S; Pham, T; Siccardi, M; Williams, A	1

Reviews

4 review(s) available for carbamazepine and rifampin

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Enzyme induction in the liver changes drug activity]. Medizinische Klinik, 1980, Sep-26, Volume: 75, Issue:20 Topics: Animals; Barbiturates; Carbamazepine; Chlorpromazine; Drug Interactions; Enzyme Induction; Glutethimide; Humans; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Rifampin; Time Factors	1980
[Drug-induced thrombocytopenia]. Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8 Topics: Abciximab; Antibodies, Monoclonal; Carbamazepine; Gold Compounds; Heparin; Humans; Immunoglobulin Fab Fragments; Platelet Glycoprotein GPIIb-IIIa Complex; Procainamide; Quinidine; Quinine; Rifampin; Thrombocytopenia; Time Factors	2007

Trials

3 trial(s) available for carbamazepine and rifampin

Article	Year
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo. Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:3 Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid	1993
Ibrutinib Dosing Strategies Based on Interaction Potential of CYP3A4 Perpetrators Using Physiologically Based Pharmacokinetic Modeling. Clinical pharmacology and therapeutics, 2016, Volume: 100, Issue:5 Topics: Adenine; Alkynes; Azithromycin; Benzoxazines; Carbamazepine; Cyclopropanes; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Dosage Calculations; Drug Interactions; Fluvoxamine; Humans; Ketoconazole; Male; Models, Biological; Piperidines; Pyrazoles; Pyrimidines; Rifampin	2016
Cytochrome P450 3A Induction Predicts P-glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine. Clinical pharmacology and therapeutics, 2018, Volume: 104, Issue:6 Topics: Adolescent; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotransformation; Carbamazepine; Computer Simulation; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inducers; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Female; Healthy Volunteers; Humans; Male; Membrane Transport Modulators; Middle Aged; Models, Biological; Organic Anion Transporters; Pregnane X Receptor; Rifabutin; Rifampin; Risk Assessment; Sofosbuvir; Substrate Specificity; Young Adult	2018

Other Studies

47 other study(ies) available for carbamazepine and rifampin

Article	Year
Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin. The Journal of biological chemistry, 2001, May-04, Volume: 276, Issue:18 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Dimerization; DNA; DNA Primers; Gene Expression Regulation; Humans; Intestinal Mucosa; Intestines; Molecular Sequence Data; Pregnane X Receptor; Promoter Regions, Genetic; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Retinoid X Receptors; Rifampin; Transcription Factors	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
SCY-635, a novel nonimmunosuppressive analog of cyclosporine that exhibits potent inhibition of hepatitis C virus RNA replication in vitro. Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2 Topics: Animals; Antiviral Agents; Cell Line; Cells, Cultured; Cyclophilin A; Cyclosporins; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Haplorhini; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Immunosuppressive Agents; Interleukin-2; Jurkat Cells; Leukocytes, Mononuclear; Mice; Molecular Structure; Rats; RNA, Viral; Virus Replication	2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Species independence in brain tissue binding using brain homogenates. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Animals; Brain; Dogs; Guinea Pigs; Humans; Macaca fascicularis; Mice; Rats; Species Specificity	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Quantitative prediction of CYP2B6 induction by estradiol during pregnancy: potential explanation for increased methadone clearance during pregnancy. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:2 Topics: Analgesics, Opioid; Aryl Hydrocarbon Hydroxylases; Biotransformation; Bupropion; Carbamazepine; Cells, Cultured; Cytochrome P-450 CYP2B6; Dose-Response Relationship, Drug; Enzyme Induction; Estradiol; Female; Hepatocytes; Humans; Hydroxylation; Metabolic Clearance Rate; Methadone; Oxidoreductases, N-Demethylating; Pregnancy; Primary Cell Culture; Rifampin; RNA, Messenger; Substrate Specificity; Up-Regulation	2013
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain. Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7 Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2014
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery. Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7 Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics	2015
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Benzyl and benzoyl benzoic acid inhibitors of bacterial RNA polymerase-sigma factor interaction. European journal of medicinal chemistry, 2020, Dec-15, Volume: 208 Topics: Animals; Bacteria; Bacterial Proteins; Benzoates; Benzophenones; Benzyl Compounds; DNA-Directed RNA Polymerases; Microbial Sensitivity Tests; Microsomes, Liver; Protein Binding; Rats; Sigma Factor	2020
Letter: Epanutin and isoniazid interaction. British medical journal, 1975, Jan-18, Volume: 1, Issue:5950 Topics: Adult; Carbamazepine; Drug Interactions; Electroencephalography; Epilepsy; Ethambutol; Ethosuximide; Female; Humans; Isoniazid; Phenobarbital; Phenytoin; Rifampin	1975
Interaction of azoles with rifampin, phenytoin, and carbamazepine: in vitro and clinical observations. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1992, Volume: 14, Issue:1 Topics: Adult; Aged; Antifungal Agents; Azoles; Carbamazepine; Coccidioides; Cryptococcus neoformans; Drug Interactions; Drug Therapy, Combination; Female; Fluconazole; Humans; Itraconazole; Ketoconazole; Malassezia; Male; Middle Aged; Mycoses; Phenytoin; Rifampin	1992
Effects of drugs on aminophylline elimination in rats. Arzneimittel-Forschung, 1988, Volume: 38, Issue:12 Topics: Aminophylline; Animals; Behavior, Animal; Carbamazepine; Cimetidine; Drug Combinations; Drug Interactions; Erythromycin; Female; Half-Life; Phenobarbital; Phenytoin; Rats; Rats, Inbred Strains; Rifampin; Sulfamethoxazole; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination	1988
Lack of effect of carbamazepine on serum alpha 1-acid glycoprotein concentration. Clinical chemistry, 1985, Volume: 31, Issue:7 Topics: Carbamazepine; Epilepsy; Humans; Immunodiffusion; Male; Orosomucoid; Rifampin; Sex Hormone-Binding Globulin; Time Factors	1985
[Carbamazepine-tuberculostatics interaction]. Medicina clinica, 1984, Dec-15, Volume: 83, Issue:20 Topics: Carbamazepine; Child; Drug Interactions; Female; Humans; Isoniazid; Rifampin	1984
[Fatal liver cell necrosis after short-term administration of isoniazid and rifampicin to a patient already under treatment with anti-epileptic agents]. Nederlands tijdschrift voor geneeskunde, 1983, May-21, Volume: 127, Issue:21 Topics: Adult; Carbamazepine; Female; Hepatic Encephalopathy; Humans; Isoniazid; Liver; Necrosis; Rifampin	1983
Induction of cytochrome P450 3A (CYP 3A) by E 5110, a non-steroidal anti-inflammatory agent (NSAID), and typical CYP 3A inducers in primary cultures of dog hepatocytes. Biological & pharmaceutical bulletin, 1995, Volume: 18, Issue:8 Topics: 7-Alkoxycoumarin O-Dealkylase; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Cells, Cultured; Clofibrate; Clotrimazole; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dogs; Drug Interactions; Enzyme Induction; Liver; Male; Mixed Function Oxygenases; Omeprazole; Phenobarbital; Phenytoin; Pyrrolidinones; Rifampin; Steroid Hydroxylases	1995
Comparison of the anticoagulant and antithrombotic effects of YM-75466, a novel orally-active factor Xa inhibitor, and warfarin in mice. Japanese journal of pharmacology, 1998, Volume: 78, Issue:2 Topics: Administration, Oral; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Anticoagulants; Anticonvulsants; Antifibrinolytic Agents; Blood Coagulation; Carbamazepine; Cimetidine; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Erythromycin; Factor Xa Inhibitors; Fibrinolytic Agents; Hemorrhage; Male; Mice; Mice, Inbred ICR; Partial Thromboplastin Time; Phenytoin; Piperidines; Prothrombin Time; Rifampin; Sulfonamides; Thromboembolism; Thromboplastin; Vitamin K 1; Warfarin	1998
A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro. Xenobiotica; the fate of foreign compounds in biological systems, 1999, Volume: 29, Issue:3 Topics: Alkaline Phosphatase; beta-Naphthoflavone; Caffeine; Carbamazepine; Carcinoma, Hepatocellular; Clofibrate; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Glucocorticoids; Hormone Antagonists; Humans; Isoniazid; Mifepristone; Mixed Function Oxygenases; Phenobarbital; Phenylbutazone; Phenytoin; Receptors, Glucocorticoid; Recombinant Proteins; Rifampin; Tumor Cells, Cultured; Xenobiotics	1999
The quantitative prediction of in vivo enzyme-induction caused by drug exposure from in vitro information on human hepatocytes. Drug metabolism and pharmacokinetics, 2005, Volume: 20, Issue:4 Topics: Area Under Curve; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Liver; Phenobarbital; Predictive Value of Tests; Rifampin	2005
Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction. Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:10 Topics: Algorithms; Carbamazepine; Cell Line; Cell Proliferation; Cell Survival; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Nifedipine; Phenobarbital; Phenytoin; Pioglitazone; Reproducibility of Results; Rifampin; Rosiglitazone; Sulfinpyrazone; Thiazolidinediones	2006
Induction of P-glycoprotein in lymphocytes by carbamazepine and rifampicin: the role of nuclear hormone response elements. British journal of clinical pharmacology, 2006, Volume: 62, Issue:2 Topics: Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Carbamazepine; Cell Line; Cells, Cultured; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Female; Humans; Leukocytes, Mononuclear; Male; Promoter Regions, Genetic; Response Elements; Reverse Transcriptase Polymerase Chain Reaction; Rifampin; RNA, Messenger; Transfection	2006
In vitro model for the prediction of clinical CYP3A4 induction using HepaRG cells. Xenobiotica; the fate of foreign compounds in biological systems, 2009, Volume: 39, Issue:11 Topics: Anticonvulsants; Biological Assay; Carbamazepine; Cell Line; Cytochrome P-450 CYP3A; Enzyme Induction; Enzyme Inhibitors; Hepatocytes; Humans; Phenobarbital; Rifampin	2009
Does the long plasma half-life of 4beta-hydroxycholesterol impact its utility as a cytochrome P450 3A (CYP3A) metric? Journal of clinical pharmacology, 2010, Volume: 50, Issue:11 Topics: Biomarkers; Carbamazepine; Computer Simulation; Cytochrome P-450 CYP3A; Enzyme Induction; Enzyme Inhibitors; Half-Life; Humans; Hydroxycholesterols; Models, Biological; Rifampin; Time Factors	2010
A 96-well plate assay for CYP4503A induction using cryopreserved human hepatocytes. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:11 Topics: Biological Assay; Carbamazepine; Cell Culture Techniques; Cell Membrane; Cells, Cultured; Cryopreservation; Cytochrome P-450 CYP3A; Dose-Response Relationship, Drug; Drug-Related Side Effects and Adverse Reactions; Enzyme Induction; Gene Expression Regulation, Enzymologic; Hepatocytes; Humans; Pharmaceutical Preparations; Phenytoin; Reverse Transcriptase Polymerase Chain Reaction; Rifampin	2010
Simulation of clinical drug-drug interactions from hepatocyte CYP3A4 induction data and its potential utility in trial designs. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Area Under Curve; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Midazolam; Nifedipine; Phenobarbital; Rifampin; Simvastatin; Substrate Specificity	2011
[Convulsions due to an interaction between anti-epileptic drugs and rifampicin]. Nederlands tijdschrift voor geneeskunde, 2014, Volume: 158 Topics: Anticonvulsants; Carbamazepine; Clonazepam; Cytochrome P-450 Enzyme System; Drug Interactions; Epilepsy; Female; Floxacillin; Humans; Middle Aged; Rifampin; Seizures; Valproic Acid	2014
Predicting the Effect of CYP3A Inducers on the Pharmacokinetics of Substrate Drugs Using Physiologically Based Pharmacokinetic (PBPK) Modeling: An Analysis of PBPK Submissions to the US FDA. Clinical pharmacokinetics, 2016, Volume: 55, Issue:4 Topics: Carbamazepine; Computer Simulation; Cytochrome P-450 CYP3A Inducers; Humans; Models, Biological; Rifabutin; Rifampin; Software; Substrate Specificity; United States; United States Food and Drug Administration	2016
Concomitant administration of rifampicin and oxcarbazepine results in a significant decrease of the active MHD metabolite of oxcarbazepine. European journal of clinical pharmacology, 2016, Volume: 72, Issue:3 Topics: Acne Vulgaris; Adult; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Drug Interactions; Epilepsy; Female; Humans; Oxcarbazepine; Rifampin	2016
Prediction of Drug-Drug Interactions Arising from CYP3A induction Using a Physiologically Based Dynamic Model. Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:6 Topics: Administration, Oral; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Gastrointestinal Tract; Hepatocytes; Humans; Liver; Models, Biological; Phenobarbital; Phenytoin; Rifampin; RNA, Messenger	2016
Transcriptional and Post-Transcriptional Regulation of Duodenal P-Glycoprotein and MRP2 in Healthy Human Subjects after Chronic Treatment with Rifampin and Carbamazepine. Molecular pharmaceutics, 2019, 09-03, Volume: 16, Issue:9 Topics: Adult; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carbamazepine; Duodenum; Female; Gene Expression; Humans; Intestinal Mucosa; Male; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Pregnane X Receptor; Receptors, Calcium-Sensing; Research Subjects; Rifampin; RNA Processing, Post-Transcriptional; RNA, Messenger; Transcription, Genetic; Young Adult	2019
Quantitative Assessment of Levonorgestrel Binding Partner Interplay and Drug-Drug Interactions Using Physiologically Based Pharmacokinetic Modeling. CPT: pharmacometrics & systems pharmacology, 2021, Volume: 10, Issue:1 Topics: Adult; Alkynes; Benzoxazines; Body Mass Index; Carbamazepine; Clarithromycin; Computer Simulation; Contraceptives, Oral, Combined; Cyclopropanes; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Drug Combinations; Drug Interactions; Ethinyl Estradiol; Female; Humans; Itraconazole; Levonorgestrel; Models, Biological; Obesity; Rifampin; Sex Hormone-Binding Globulin	2021
The Impact of Strong Inducers on Direct Oral Anticoagulant Levels. The American journal of medicine, 2021, Volume: 134, Issue:10 Topics: Administration, Oral; Aged; Anticoagulants; Carbamazepine; Cytochrome P-450 Enzyme Inducers; Drug Interactions; Drug Monitoring; Female; Humans; Male; Phenobarbital; Phenytoin; Retrospective Studies; Rifampin	2021
Study of the metabolic stability profiles of perampanel, rufinamide and stiripentol and prediction of drug interactions using HepaRG cells as an in vitro human model. Toxicology in vitro : an international journal published in association with BIBRA, 2022, Volume: 82 Topics: Anticonvulsants; Carbamazepine; Cytochrome P-450 Enzyme Inducers; Dioxolanes; Drug Interactions; Humans; Nitriles; Phenobarbital; Pyridones; Rifampin; Triazoles	2022
General Framework to Quantitatively Predict Pharmacokinetic Induction Drug-Drug Interactions Using In Vitro Data. Clinical pharmacokinetics, 2023, Volume: 62, Issue:5 Topics: Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Humans; Models, Biological; Rifampin	2023