carbamazepine and ranitidine

carbamazepine has been researched along with ranitidine in 40 studies

Research

Studies (40)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (5.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	12 (30.00)	29.6817
2010's	26 (65.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL	1
Faassen, F; Spanings, H; Vogel, G; Vromans, H	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Ahman, M; Holmén, AG; Wan, H	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Avdeef, A; Tam, KY	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Connelly, MC; Fujii, N; Mahindroo, N; Punchihewa, C; Yan, B; Yang, L	1
Ekins, S; Williams, AJ; Xu, JJ	1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Ara, T; Arnold, LA; Baranowski, AM; Bikle, DD; Guy, RK; Lynt, WZ; McCallum, MM; Nandhikonda, P; Pearson, D; Yuan, NY	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Artursson, P; Mateus, A; Matsson, P	1
Arnold, LA; Bikle, DD; Cook, JM; Feleke, B; McCallum, MM; Nandhikonda, P; Nassif, N; Sidhu, PS; Singh, RK; Teske, K; Yuan, NY	1
Li, F; Liu, Y; Wang, W; Wu, L; Yan, B; Zhang, Q; Zhou, H; Zhu, H	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Campillo, NE; Cañada, FJ; Canales, A; Carvalho, I; Chierrito, TPC; Martinez, A; Martínez-Gonzalez, L; Pedersoli-Mantoani, S; Perez, C; Pérez, DI; Roca, C; Sebastian-Pérez, V	1
Arnold, LA; Balakrishnan, K; Chen, W; Fan, H; Fan, Y; Gandhi, V; Peng, X; Sun, H; Wang, Y	1
Bassett, R; Budhraja, A; Das, S; Ling, T; Maier, J; Opferman, JT; Potts, MB; Rankovic, Z; Rivas, F; Shelat, A	1
Dalton, MJ; Messenheimer, JA; Powell, JR	1
Jones, DB; Mihaly, GW; Phillips, JA; Smallwood, RA; Vajda, FJ; Webster, LK	1
Adams, RC; Furness, MS; Gill, DS; Holcombe, FO; Raw, AS; Yu, LX	1
Preskorn, SH	1
Li, B; Yu, K; Zhang, T	1
Martínez, F; Melero, JA; Molina, R; Vasiliadou, IA	1
Bracale, M; Bruno, A; De Mattia, F; Labra, M; Marsoni, M; Vannini, C	1
Ahn, YM; Bae, HJ; Eun, JW; Jin, CY; Kang, HJ; Kim, H; Kim, HS; Lee, JY; Nam, SW; Park, SJ; Park, WS; Shen, Q; Shin, WC; Yang, HD; You, JS	1

Reviews

2 review(s) available for carbamazepine and ranitidine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Regulatory considerations of pharmaceutical solid polymorphism in Abbreviated New Drug Applications (ANDAs). Advanced drug delivery reviews, 2004, Feb-23, Volume: 56, Issue:3 Topics: Biological Availability; Carbamazepine; Cefuroxime; Chemistry Techniques, Analytical; Crystallography; Decision Trees; Drug Approval; Drug Stability; Drugs, Generic; Enalapril; Humans; Molecular Conformation; Phase Transition; Prazosin; Quality Control; Ranitidine; Solubility; Sulfonamides; Technology, Pharmaceutical; Therapeutic Equivalency; Torsemide; United States; United States Food and Drug Administration; Warfarin	2004

Article

Year

DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.

Drug discovery today, 2016, Volume: 21, Issue:4

Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Regulatory considerations of pharmaceutical solid polymorphism in Abbreviated New Drug Applications (ANDAs).

Advanced drug delivery reviews, 2004, Feb-23, Volume: 56, Issue:3

Topics: Biological Availability; Carbamazepine; Cefuroxime; Chemistry Techniques, Analytical; Crystallography; Decision Trees; Drug Approval; Drug Stability; Drugs, Generic; Enalapril; Humans; Molecular Conformation; Phase Transition; Prazosin; Quality Control; Ranitidine; Solubility; Sulfonamides; Technology, Pharmaceutical; Therapeutic Equivalency; Torsemide; United States; United States Food and Drug Administration; Warfarin

2004

Trials

2 trial(s) available for carbamazepine and ranitidine

Article	Year
Ranitidine does not alter single-dose carbamazepine pharmacokinetics in healthy adults. Drug intelligence & clinical pharmacy, 1985, Volume: 19, Issue:12 Topics: Adult; Biological Availability; Carbamazepine; Drug Interactions; Half-Life; Humans; Kinetics; Male; Ranitidine	1985
Effect of cimetidine and ranitidine on carbamazepine and sodium valproate pharmacokinetics. European journal of clinical pharmacology, 1984, Volume: 27, Issue:3 Topics: Carbamazepine; Cimetidine; Drug Interactions; Female; Humans; Kinetics; Male; Mixed Function Oxygenases; Ranitidine; Valproic Acid	1984

Other Studies

36 other study(ies) available for carbamazepine and ranitidine

Article	Year
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Cheminformatic models to predict binding affinities to human serum albumin. Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25 Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids	2001
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs. International journal of pharmaceutics, 2003, Sep-16, Volume: 263, Issue:1-2 Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport	2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability? Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9 Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Amide conjugates of ketoprofen and indole as inhibitors of Gli1-mediated transcription in the Hedgehog pathway. Bioorganic & medicinal chemistry, 2010, Jul-01, Volume: 18, Issue:13 Topics: Amides; Cell Line; Cell Membrane Permeability; Genes, Reporter; Hedgehog Proteins; Humans; Indoles; Ketoprofen; Kruppel-Like Transcription Factors; Microsomes; Nuclear Proteins; Transcription Factors; Transcription, Genetic; Zinc Finger Protein GLI1; Zinc Finger Protein Gli2	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
QSAR-based permeability model for drug-like compounds. Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8 Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Discovery of the first irreversible small molecule inhibitors of the interaction between the vitamin D receptor and coactivators. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Cell Line; High-Throughput Screening Assays; Humans; Indoles; Membranes, Artificial; Methylamines; Nuclear Receptor Coactivator 2; Nuclear Receptor Coactivator 3; Nuclear Receptor Coactivators; Permeability; Protein Binding; Receptors, Calcitriol; Solubility; Structure-Activity Relationship; Transcription, Genetic; TRPV Cation Channels	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain. Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7 Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization	2014
Development of novel Vitamin D Receptor-Coactivator Inhibitors. ACS medicinal chemistry letters, 2014, Feb-13, Volume: 5, Issue:2 Topics:	2014
Improving both aqueous solubility and anti-cancer activity by assessing progressive lead optimization libraries. Bioorganic & medicinal chemistry letters, 2015, May-01, Volume: 25, Issue:9 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Fibroblasts; High-Throughput Screening Assays; Humans; Molecular Structure; Small Molecule Libraries; Solubility; Structure-Activity Relationship; Thiazolidines; Water	2015
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors. European journal of medicinal chemistry, 2018, Feb-10, Volume: 145 Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Indoles; Molecular Structure; Piperidines; Structure-Activity Relationship	2018
Discovery and Optimization of Novel Hydrogen Peroxide Activated Aromatic Nitrogen Mustard Derivatives as Highly Potent Anticancer Agents. Journal of medicinal chemistry, 2018, 10-25, Volume: 61, Issue:20 Topics: Antineoplastic Agents, Alkylating; Boronic Acids; Cell Line, Tumor; Drug Design; Esters; Humans; Hydrogen Peroxide; Nitrogen Mustard Compounds	2018
Identification of substituted 5-membered heterocyclic compounds as potential anti-leukemic agents. European journal of medicinal chemistry, 2019, Feb-15, Volume: 164 Topics: Animals; Antineoplastic Agents; Apoptosis; Caspases; Cell Line, Tumor; Drug Evaluation, Preclinical; Enzyme Induction; Heterocyclic Compounds; Humans; Leukemia; Mice; Small Molecule Libraries; Therapeutic Index	2019
Deconstructing a medication regimen. Journal of psychiatric practice, 2008, Volume: 14, Issue:2 Topics: Adolescent; Antimanic Agents; Antipsychotic Agents; Benztropine; Biotransformation; Bipolar Disorder; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Female; Fluoxetine; Humans; Lithium Carbonate; Metabolic Clearance Rate; Ranitidine; Risperidone; Stupor; Valproic Acid	2008
Direct rapid analysis of multiple PPCPs in municipal wastewater using ultrahigh performance liquid chromatography-tandem mass spectrometry without SPE pre-concentration. Analytica chimica acta, 2012, Aug-13, Volume: 738 Topics: Acyclovir; Benzophenones; Carbamazepine; Chromatography, High Pressure Liquid; Fluconazole; Fluoxetine; Hong Kong; Metronidazole; Parabens; Pharmaceutical Preparations; Ranitidine; Sewage; Solid Phase Extraction; Sunscreening Agents; Tandem Mass Spectrometry	2012
Experimental and modeling study on removal of pharmaceutically active compounds in rotating biological contactors. Journal of hazardous materials, 2014, Jun-15, Volume: 274 Topics: Adsorption; Biofilms; Bioreactors; Caffeine; Carbamazepine; Models, Theoretical; Pharmaceutical Preparations; Ranitidine; Sulfamethoxazole; Waste Disposal, Fluid; Water Pollutants, Chemical	2014
Uptake and effects of a mixture of widely used therapeutic drugs in Eruca sativa L. and Zea mays L. plants. Ecotoxicology and environmental safety, 2014, Volume: 108 Topics: Albuterol; Atenolol; Bezafibrate; Brassicaceae; Carbamazepine; Cyclophosphamide; Drug Interactions; Germination; Humans; Lincomycin; Ofloxacin; Pharmaceutical Preparations; Ranitidine; Rivers; Tandem Mass Spectrometry; Wastewater; Water Pollutants, Chemical; Zea mays	2014
Characteristic molecular and proteomic signatures of drug-induced liver injury in a rat model. Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:2 Topics: Animals; Biomarkers; Carbamazepine; Chemical and Drug Induced Liver Injury; Chlorpromazine; Disease Models, Animal; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Enalapril; Gene Expression; Liver; Male; Oligonucleotide Array Sequence Analysis; Proteomics; Pyrazinamide; Ranitidine; Rats; Rats, Sprague-Dawley; Transcriptome	2015