carbamazepine and propranolol

carbamazepine has been researched along with propranolol in 105 studies

Research

Studies (105)

TimeframeStudies, this research(%)All Research%
pre-199013 (12.38)18.7374
1990's12 (11.43)18.2507
2000's27 (25.71)29.6817
2010's47 (44.76)24.3611
2020's6 (5.71)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Blake, JF; Curatolo, WJ; Lombardo, F1
Strassburg, CP; Tukey, RH1
Danelian, E; Hämäläinen, MD; Hansson, A; Karlén, A; Karlsson, R; Lennernäs, H; Löfâs, S; Winiwarter, S1
Topliss, JG; Yoshida, F1
Faller, B; Wohnsland, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Hwang, KK; Mandagere, AK; Thompson, TN1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Giralt, E; Malakoutikhah, M; Teixidó, M1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Botta, M; Dreassi, E; Falchi, F; Maga, G; Santucci, A; Schenone, S; Zizzari, AT1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Giralt, E; Malakoutikhah, M; Prades, R; Teixidó, M1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Glen, RC; Lowe, R; Mitchell, JB1
Ekins, S; Williams, AJ; Xu, JJ1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Bříza, T; D'Acunto, CW; Gbelcová, H; Havlík, M; Kaplánek, R; Kejík, Z; Král, V; Ruml, T; Vasina, L1
Azas, N; Boudot, C; Bourgeade-Delmas, S; Boutet-Robinet, E; Courtioux, B; Fairlamb, A; Hutter, S; Laget, M; Moreau, A; Mothes, E; Paloque, L; Pedron, J; Pratviel, G; Sournia-Saquet, A; Stigliani, JL; Valentin, A; Vendier, L; Verhaeghe, P; Wyllie, S1
Bae, MA; Choi, J; Choi, JH; Kim, MJ; Kim, YC; Lee, D; Lee, KR; Lee, S; Park, CJ; Seo, J; Shin, DS; Song, YK1
Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S1
von Wichert, P1
Rane, A; Wilson, JT1
Mandoki, MW; Matthews-Ferrari, K; Sumner, GS1
Christison, GW; Kirch, DG; Wyatt, RJ1
Mattes, JA4
Brotman, AW; Ford, HE; Renshaw, PF1
Barnes, R; Risse, SC1
Lerer, B1
Baldessarini, RJ; Donaldson, SR; Gelenberg, AJ1
Sheard, MH1
Cavalieri, RR; Pitt-Rivers, R1
Mattes, JA; Mays, D; Rosenberg, J1
Müller, FO; Steyn, JM1
Levenson, J; Pandurangi, A; Silverman, J; Vieweg, V1
Mayer, T; Specht, U1
Vanelle, JM1
Cowley, DS; Ries, RK; Roy-Byrne, PP; Sullivan, MD1
Grahn, A; Hermansson, J1
Campos, J; Carvalho, MJ; Costa, O; Cunha, DL; Freitas, AF; Freitas, J; Garcia, JM; Gomes, MC; Puig, J1
De Sarro, A; De Sarro, G; Di Paola, ED; Ferreri, G; Fischer, W1
Ferrari, B; Fraysse, B; Garric, J; Lo Giudice, R; Mons, R; Paxéus, N; Pollio, A; Vollat, B1
Drillia, P; Fountoulakis, M; Lyberatos, G; Stamatelatou, K1
Dokianakis, SN; Kornaros, ME; Lyberatos, G1
Drillia, P; Lyberatos, G; Stamatelatou, K1
Biebow, M; Boller, M; Pronk, W1
Landess, JS; Martin, PR; Raj, V1
Adriaensen, J; Augustijns, P; Brewster, ME; Mackie, C; Melis, A; Mensch, J; Noppe, M1
Kawasaki, A; Purvin, VA; Williams, PE1
Kalgutkar, AS; Obach, RS; Soglia, JR; Zhao, SX1
Cooks, RG; Ifa, DR; Kistler, T; Manicke, NE; Ouyang, Z1
Banks, E; Grover, D; Jiang, JQ; Zhang, ZL; Zhou, JL1
Barceló, D; Caminal, G; Marco-Urrea, E; Petrović, M; Radjenović, J; Vicent, T1
Maskaoui, K; Zhou, JL1
Barreiro, JC; Cass, QB; Madureira, TV; Rocha, E; Rocha, MJ; Tiritan, ME1
Koester, LS; Kratz, JM; Simões, CM; Teixeira, MR1
Cruzeiro, C; Madureira, TV; Rocha, E; Rocha, MJ1
Kühne, S; Steinert, M; Untucht, C; Wätzig, H1
Alonso, E; Aparicio, I; Camacho-Muñoz, MA; Martín, J; Santos, JL1
Cruzeiro, C; Madureira, TV; Monteiro, RA; Rocha, E; Rocha, MJ; Rodrigues, I1
Jasper, JT; Sedlak, DL1
Hui-Ping Khor, A; Lim, KS; Lo, YL; Ng, CC; Yeap, LL1
Cho, K; Choi, KJ; Hong, SW; Jeong, B; Lee, C; Lee, J; Lee, Y; Maeng, SK1
Barata, C; Campos, B; Rivetti, C1
Batley, GE; Hutchinson, TH; Kumar, A; Nidumolu, B1
Ali, R; Bodmeier, R; Dashevsky, A1
Baranowska, I; Buszewski, B; Gadzała-Kopciuch, R; Kochańska, K; Konieczka, P; Kościelniak, P; Magiera, S; Namieśnik, J; Polkowska-Motrenko, H; Rutkowska, M; Samczyński, Z; Woźniakiewicz, A1
Fabbri, E; Franzellitti, S; Pretolani, F; Striano, T1
Baron, MG; Hetheridge, MJ; Jackson, SK; Jha, AN; Mintram, KS; Moody, AJ; Owen, SF; Purcell, WM1
Simpson, AJ; Simpson, MJ; Wagner, ND1
Abe, K; Hashimura, M; Iha, HA; Iwai, C; Kato, M; Kawaji, S; Kawakita, K; Kunisawa, N; Ogawa, M; Ohno, Y; Shimizu, S1
García-Espinoza, JD; Mijaylova Nacheva, P1
Ali, R; Chaerunisaa, AY; Dashevskiy, A1
Hollender, J; Jeon, J1
Balbi, T; Canesi, L; Fabbri, E; Fabbri, R; Franzellitti, S; Montagna, M; Valbonesi, P1
Chen, S; Hu, Y; Huang, W; Luo, Y; Wang, P; Wen, W; Wu, J; Xiang, L; Xu, S; Yang, Y1
Ali, R; Bodmeier, R; Chaerunisaa, AY; Körber, M1
Chang, H; Chen, C; Du, H; Guan, C; Li, C; Qiu, L; Wang, S; Wang, T; Wu, Y; Zhang, L; Zhang, S; Zhou, H1
Bodmeier, R; Chaerunisaa, AY; Muhaimin, M1

Reviews

12 review(s) available for carbamazepine and propranolol

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
When symptoms persist: choosing among alternative somatic treatments for schizophrenia.
    Schizophrenia bulletin, 1991, Volume: 17, Issue:2

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clozapine; Double-Blind Method; Electroconvulsive Therapy; Humans; Levodopa; Lithium; Propranolol; Reserpine; Schizophrenia

1991
Pharmacologic treatment of agitation associated with dementia.
    Journal of the American Geriatrics Society, 1986, Volume: 34, Issue:5

    Topics: Affective Symptoms; Aged; Aggression; Alzheimer Disease; Anti-Anxiety Agents; Antipsychotic Agents; Anxiety; Benzodiazepines; Bipolar Disorder; Carbamazepine; Dementia; Humans; Lithium; Lithium Carbonate; Propranolol; Psychotropic Drugs

1986
Psychopharmacology of temper outbursts. A review.
    The Journal of nervous and mental disease, 1986, Volume: 174, Issue:8

    Topics: Adolescent; Aggression; Anger; Animals; Carbamazepine; Child; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lithium; Male; Mental Disorders; Propranolol; Rage; Thyroid Gland

1986
Alternative therapies for bipolar disorder.
    The Journal of clinical psychiatry, 1985, Volume: 46, Issue:8

    Topics: Ascorbic Acid; Bipolar Disorder; Bupropion; Carbamazepine; Choline; Clonazepam; Clonidine; Clorgyline; Demeclocycline; Fenfluramine; Humans; Methylene Blue; Phosphatidylcholines; Physostigmine; Propiophenones; Propranolol; Spironolactone; Thyroxine; Tryptophan; Valproic Acid

1985
Clinical pharmacology of aggressive behavior.
    Clinical neuropharmacology, 1984, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Aged; Aggression; Anger; Anti-Anxiety Agents; Benzodiazepines; Brain Chemistry; Carbamazepine; Child; Child Abuse; Child, Preschool; Epilepsy; Female; gamma-Aminobutyric Acid; Humans; Lithium; Male; Middle Aged; Mood Disorders; Prisoners; Propranolol; Psychotic Disorders

1984
The effects of drugs on the distribution and metabolism of thyroid hormones.
    Pharmacological reviews, 1981, Volume: 33, Issue:2

    Topics: Animals; Antithyroid Agents; Carbamazepine; Carcinogens; Female; Heparin; Hormones; Humans; Male; Phenobarbital; Phenytoin; Pregnancy; Propranolol; Salicylates; Thyroid Hormones; Thyroxine-Binding Proteins

1981
The consulting psychiatrist and the polydipsia-hyponatremia syndrome in schizophrenia.
    International journal of psychiatry in medicine, 1994, Volume: 24, Issue:4

    Topics: Angiotensin II; Anti-Inflammatory Agents, Non-Steroidal; Antipsychotic Agents; Carbamazepine; Cognition Disorders; Demeclocycline; Drinking Behavior; Electroconvulsive Therapy; Humans; Hyponatremia; Lithium; Mood Disorders; Naloxone; Phenytoin; Polyuria; Propranolol; Psychiatry; Psychotherapy; Schizophrenia; Sodium Chloride; Syndrome; Water Intoxication; Workforce

1994
[Resistant schizophrenia: what chemotherapy?].
    Annales medico-psychologiques, 1993, Volume: 151, Issue:4

    Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clozapine; Drug Therapy, Combination; Humans; Lithium; Propranolol; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology

1993
Adjunctive treatment of benzodiazepine discontinuation syndromes: a review.
    Journal of psychiatric research, 1993, Volume: 27 Suppl 1

    Topics: Anti-Anxiety Agents; Benzodiazepines; Carbamazepine; Clonidine; Combined Modality Therapy; Humans; Panic Disorder; Propranolol; Psychotherapy; Psychotropic Drugs; Recurrence; Substance Withdrawal Syndrome

1993
[Malignant vasovagal syncope: a case of prolonged asystole induced by the "tilt" test and aggravated by therapy with a beta blocker (a clinical case and diagnostic, physiopathologic and therapeutic review)].
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1993, Volume: 12, Issue:9

    Topics: Adult; Carbamazepine; Electrocardiography; Heart Arrest; Heart Function Tests; Humans; Male; Posture; Propranolol; Scopolamine; Syncope

1993

Trials

6 trial(s) available for carbamazepine and propranolol

ArticleYear
When symptoms persist: choosing among alternative somatic treatments for schizophrenia.
    Schizophrenia bulletin, 1991, Volume: 17, Issue:2

    Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clozapine; Double-Blind Method; Electroconvulsive Therapy; Humans; Levodopa; Lithium; Propranolol; Reserpine; Schizophrenia

1991
Comparative effectiveness of carbamazepine and propranolol for rage outbursts.
    The Journal of neuropsychiatry and clinical neurosciences, 1990,Spring, Volume: 2, Issue:2

    Topics: Adolescent; Adult; Aggression; Antisocial Personality Disorder; Attention Deficit Disorder with Hyperactivity; Carbamazepine; Female; Humans; Male; Mental Disorders; Propranolol; Rage

1990
Carbamazepine vs. propranolol for rage outbursts.
    Psychopharmacology bulletin, 1988, Volume: 24, Issue:1

    Topics: Adult; Anger; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Male; Propranolol; Rage; Random Allocation

1988
Psychopharmacology of temper outbursts. A review.
    The Journal of nervous and mental disease, 1986, Volume: 174, Issue:8

    Topics: Adolescent; Aggression; Anger; Animals; Carbamazepine; Child; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lithium; Male; Mental Disorders; Propranolol; Rage; Thyroid Gland

1986
Carbamazepine versus propranolol in patients with uncontrolled rage outbursts: a random assignment study.
    Psychopharmacology bulletin, 1984,Winter, Volume: 20, Issue:1

    Topics: Adolescent; Anger; Carbamazepine; Child Behavior Disorders; Humans; Propranolol; Rage; Random Allocation

1984
Propranolol in startle induced epileptic seizures.
    Journal of neurology, neurosurgery, and psychiatry, 1995, Volume: 58, Issue:3

    Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Clobazam; Epilepsy, Complex Partial; Epilepsy, Generalized; Humans; Propranolol; Reflex, Startle

1995

Other Studies

89 other study(ies) available for carbamazepine and propranolol

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Computation of brain-blood partitioning of organic solutes via free energy calculations.
    Journal of medicinal chemistry, 1996, Nov-22, Volume: 39, Issue:24

    Topics: Animals; Blood-Brain Barrier; Brain; Cattle; Cells, Cultured; Endothelium, Vascular; Membrane Lipids; Microcirculation; Molecular Conformation; Molecular Structure; Monte Carlo Method; Permeability; Pharmaceutical Preparations; Software; Solubility; Thermodynamics

1996
SPR biosensor studies of the direct interaction between 27 drugs and a liposome surface: correlation with fraction absorbed in humans.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Humans; Intestinal Absorption; Liposomes; Pharmaceutical Preparations; Pharmacokinetics; Predictive Value of Tests; Surface Plasmon Resonance

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes.
    Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6

    Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water

2001
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Graphical model for estimating oral bioavailability of drugs in humans and other species from their Caco-2 permeability and in vitro liver enzyme metabolic stability rates.
    Journal of medicinal chemistry, 2002, Jan-17, Volume: 45, Issue:2

    Topics: Administration, Oral; Animals; Biological Availability; Caco-2 Cells; Dogs; Guinea Pigs; Humans; In Vitro Techniques; Inactivation, Metabolic; Liver; Microsomes, Liver; Models, Biological; Permeability; Pharmacokinetics; Rats; Species Specificity

2002
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
    Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19

    Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Toward an optimal blood-brain barrier shuttle by synthesis and evaluation of peptide libraries.
    Journal of medicinal chemistry, 2008, Aug-28, Volume: 51, Issue:16

    Topics: Biological Transport; Blood-Brain Barrier; Cell Survival; Drug Carriers; Humans; Levodopa; Membranes, Artificial; Peptide Library; Peptides; Permeability; Phenylalanine; Solubility

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Determination of permeability and lipophilicity of pyrazolo-pyrimidine tyrosine kinase inhibitors and correlation with biological data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:9

    Topics: Humans; Lipids; Membranes, Artificial; Permeability; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrazoles; Pyrimidines

2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
N-methyl phenylalanine-rich peptides as highly versatile blood-brain barrier shuttles.
    Journal of medicinal chemistry, 2010, Mar-25, Volume: 53, Issue:6

    Topics: Aminolevulinic Acid; Animals; Animals, Newborn; Astrocytes; Biological Transport; Blood Vessels; Blood-Brain Barrier; Brain; Cattle; Cell Membrane Permeability; Cells, Cultured; Chromatography, High Pressure Liquid; Coculture Techniques; Drug Carriers; Endothelial Cells; gamma-Aminobutyric Acid; Mass Spectrometry; Molecular Structure; Nipecotic Acids; Oligopeptides; Phenylalanine; Rats

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2

    Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution

2011
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Metallomics for Alzheimer's disease treatment: Use of new generation of chelators combining metal-cation binding and transport properties.
    European journal of medicinal chemistry, 2018, Apr-25, Volume: 150

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Cations; Cell Proliferation; Cell Survival; Chelating Agents; Chelation Therapy; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Metals; Molecular Structure; Protein Aggregates; Structure-Activity Relationship; Tumor Cells, Cultured

2018
Novel 8-nitroquinolin-2(1H)-ones as NTR-bioactivated antikinetoplastid molecules: Synthesis, electrochemical and SAR study.
    European journal of medicinal chemistry, 2018, Jul-15, Volume: 155

    Topics: Antiprotozoal Agents; Cell Survival; Dose-Response Relationship, Drug; Electrochemical Techniques; Hep G2 Cells; Humans; Kinetoplastida; Leishmania infantum; Molecular Structure; Nitroquinolines; Nitroreductases; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanosoma brucei brucei

2018
Interplay among Conformation, Intramolecular Hydrogen Bonds, and Chameleonicity in the Membrane Permeability and Cyclophilin A Binding of Macrocyclic Peptide Cyclosporin O Derivatives.
    Journal of medicinal chemistry, 2021, 06-24, Volume: 64, Issue:12

    Topics: Animals; Caco-2 Cells; Cell Membrane Permeability; Cyclization; Cyclophilin A; Cyclosporine; Cyclosporins; Drug Design; Humans; Hydrogen Bonding; Male; Mice, Inbred ICR; Molecular Conformation; Protein Binding

2021
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
    European journal of medicinal chemistry, 2021, Nov-05, Volume: 223

    Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones

2021
[Drug side-effects in the lung].
    Deutsche medizinische Wochenschrift (1946), 1978, Feb-10, Volume: 103, Issue:6

    Topics: Antineoplastic Agents; Asthma; Carbamazepine; Cromolyn Sodium; Drug-Related Side Effects and Adverse Reactions; Humans; Hypertension, Pulmonary; Nitrofurantoin; Propranolol; Pulmonary Fibrosis; Respiratory Distress Syndrome; Respiratory Insufficiency; Respiratory Tract Diseases; Sulfonamides

1978
Clinical pharmacokinetics in infants and children.
    Clinical pharmacokinetics, 1976, Volume: 1, Issue:1

    Topics: Aging; Body Water; Carbamazepine; Child; Child, Preschool; Clindamycin; Dextropropoxyphene; Diazoxide; Dicloxacillin; Digoxin; Ethosuximide; Humans; Infant; Infant, Newborn; Kidney; Kinetics; Pharmaceutical Preparations; Phenobarbital; Phenytoin; Propranolol; Sulfonamides; Tetracycline; Theophylline

1976
Practice parameters for the assessment and treatment of conduct disorders. American Academy of Child and Adolescent Psychiatry.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1992, Volume: 31, Issue:2

    Topics: Adolescent; Ambulatory Care; Antidepressive Agents; Carbamazepine; Child; Child Behavior Disorders; Female; Hospitalization; Humans; Male; Propranolol; Psychotherapy

1992
Evaluation and treatment of rage in children and adolescents.
    Child psychiatry and human development, 1992,Summer, Volume: 22, Issue:4

    Topics: Adolescent; Adolescent Behavior; Brain; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Electroencephalography; Female; Humans; Lithium Carbonate; Male; Propranolol; Rage; Tomography, X-Ray Computed; Violence; Wechsler Scales

1992
Possible synergistic anticonvulsant effect of propranolol and carbamazepine.
    The American journal of psychiatry, 1990, Volume: 147, Issue:12

    Topics: Adult; Carbamazepine; Drug Synergism; Epilepsy, Temporal Lobe; Female; Humans; Neurocognitive Disorders; Propranolol

1990
Metoprolol for intermittent explosive disorder.
    The American journal of psychiatry, 1985, Volume: 142, Issue:9

    Topics: Adult; Aggression; Anger; Carbamazepine; Humans; Male; Metoprolol; Neurocognitive Disorders; Propranolol; Rage; Violence

1985
The pharmacologic treatment of schizophrenia: a progress report.
    Schizophrenia bulletin, 1983, Volume: 9, Issue:4

    Topics: Acute Disease; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clonidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium; Lithium Carbonate; Prognosis; Propranolol; Schizophrenia; Schizophrenic Psychology

1983
Comparative effects of two commercially available blood collection tubes on plasma concentrations of drugs.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jan-26, Volume: 57, Issue:4

    Topics: Acebutolol; Blood Specimen Collection; Carbamazepine; Diazepam; Digoxin; Ethosuximide; Humans; Nordazepam; Penbutolol; Pharmaceutical Preparations; Propranolol; Quinidine; Salicylates; Time Factors; Valproic Acid; Warfarin

1980
Determination of drugs by direct injection of plasma into a biocompatible extraction column based on a protein-entrapped hydrophobic phase.
    Journal of chromatography. A, 1994, Feb-04, Volume: 660, Issue:1-2

    Topics: Biocompatible Materials; Blood Proteins; Carbamazepine; Chromatography, High Pressure Liquid; Humans; Ibuprofen; Naproxen; Pharmaceutical Preparations; Phenytoin; Propranolol; Reproducibility of Results

1994
Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice.
    European journal of pharmacology, 2002, May-10, Volume: 442, Issue:3

    Topics: Acoustic Stimulation; Adrenergic beta-Antagonists; Animals; Anticonvulsants; Atenolol; Body Temperature; Carbamazepine; Epilepsy, Reflex; Female; Lamotrigine; Male; Metoprolol; Mice; Mice, Inbred DBA; Motor Activity; Phenobarbital; Propanolamines; Propranolol; Stereoisomerism; Triazines; Valproic Acid

2002
Environmental risk assessment of six human pharmaceuticals: are the current environmental risk assessment procedures sufficient for the protection of the aquatic environment?
    Environmental toxicology and chemistry, 2004, Volume: 23, Issue:5

    Topics: Animals; Carbamazepine; Clofibric Acid; Diclofenac; Drug-Related Side Effects and Adverse Reactions; Environmental Monitoring; France; Germany; Humans; Ofloxacin; Pharmaceutical Preparations; Propranolol; Risk Assessment; Sulfamethoxazole; Toxicity Tests; Water Pollutants, Chemical

2004
Toxic effect of pharmaceuticals on methanogenesis.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2004, Volume: 50, Issue:5

    Topics: Bacteria, Anaerobic; Biomass; Carbamazepine; Clofibric Acid; Diclofenac; Drug-Related Side Effects and Adverse Reactions; Methane; Methanomicrobiales; Ofloxacin; Pharmaceutical Preparations; Propranolol; Sewage; Sulfamethoxazole; Time Factors; Toxicity Tests; Waste Disposal, Fluid

2004
On the effect of pharmaceuticals on bacterial nitrite oxidation.
    Water science and technology : a journal of the International Association on Water Pollution Research, 2004, Volume: 50, Issue:5

    Topics: Bacteria, Anaerobic; Biodegradation, Environmental; Bioreactors; Carbamazepine; Cities; Clofibrate; Diclofenac; Drug-Related Side Effects and Adverse Reactions; Kinetics; Nitrites; Nitrogen; Ofloxacin; Oxidation-Reduction; Pharmaceutical Preparations; Propranolol; Sewage; Sulfamethoxazole; Triclosan; Waste Disposal, Fluid; Water Purification

2004
Fate and mobility of pharmaceuticals in solid matrices.
    Chemosphere, 2005, Volume: 60, Issue:8

    Topics: Adsorption; Aluminum Silicates; Bacteria, Aerobic; Bacteria, Anaerobic; Carbamazepine; Carbon; Clay; Clofibric Acid; Diclofenac; Models, Theoretical; Ofloxacin; Pharmaceutical Preparations; Propranolol; Sewage; Soil; Sulfamethoxazole; Water Movements; Water Pollutants, Chemical

2005
Electrodialysis for recovering salts from a urine solution containing micropollutants.
    Environmental science & technology, 2006, Apr-01, Volume: 40, Issue:7

    Topics: Carbamazepine; Dialysis; Diclofenac; Electrochemistry; Ibuprofen; Propranolol; Salts; Water Pollutants, Chemical

2006
Oxcarbazepine use in essential tremor.
    The Annals of pharmacotherapy, 2006, Volume: 40, Issue:10

    Topics: Adult; Carbamazepine; Essential Tremor; Female; Humans; Oxcarbazepine; Propranolol

2006
Novel generic UPLC/MS/MS method for high throughput analysis applied to permeability assessment in early Drug Discovery.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2007, Mar-01, Volume: 847, Issue:2

    Topics: Ampicillin; Atenolol; Caffeine; Carbamazepine; Chromatography, High Pressure Liquid; Griseofulvin; Permeability; Pharmaceutical Preparations; Propranolol; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2007
Superior oblique myokymia: efficacy of medical treatment.
    Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2007, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Diplopia; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Optical Illusions; Phenytoin; Propranolol; Retrospective Studies; Treatment Outcome; Trochlear Nerve Diseases; Valproic Acid

2007
Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose.
    Chemical research in toxicology, 2008, Volume: 21, Issue:9

    Topics: Acetaminophen; Binding Sites; Buspirone; Carbamazepine; Diclofenac; Diphenhydramine; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hepatocytes; Humans; Indomethacin; Meloxicam; Microsomes, Liver; Molecular Structure; Paroxetine; Piperazines; Propranolol; Raloxifene Hydrochloride; Simvastatin; Structure-Activity Relationship; Thiazines; Thiazoles; Ticrynafen; Toxicity Tests; Triazoles

2008
High-throughput quantitative analysis by desorption electrospray ionization mass spectrometry.
    Journal of the American Society for Mass Spectrometry, 2009, Volume: 20, Issue:2

    Topics: Animals; Automation; Brain Chemistry; Carbamazepine; Pharmaceutical Preparations; Propranolol; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Swine

2009
Pharmaceutical residues in wastewater treatment works effluents and their impact on receiving river water.
    Journal of hazardous materials, 2009, Jul-30, Volume: 166, Issue:2-3

    Topics: Carbamazepine; Diclofenac; Indomethacin; Pharmaceutical Preparations; Propranolol; Rivers; Sulfamethoxazole; United Kingdom; Water Pollutants, Chemical

2009
Oxidation of atenolol, propranolol, carbamazepine and clofibric acid by a biological Fenton-like system mediated by the white-rot fungus Trametes versicolor.
    Water research, 2010, Volume: 44, Issue:2

    Topics: Atenolol; Benzoquinones; Biodegradation, Environmental; Carbamazepine; Clofibric Acid; Hydrogen Peroxide; Iron; Oxalates; Oxidation-Reduction; Pharmaceutical Preparations; Propranolol; Trametes; Waste Disposal, Fluid; Water Pollutants, Chemical

2010
Colloids as a sink for certain pharmaceuticals in the aquatic environment.
    Environmental science and pollution research international, 2010, Volume: 17, Issue:4

    Topics: Carbamazepine; Colloids; Diclofenac; Environmental Restoration and Remediation; Fresh Water; Indomethacin; Meclofenamic Acid; Pharmaceutical Preparations; Phenethylamines; Propranolol; Sewage; Sulfamethoxazole; Tamoxifen; Thioridazine; Water Pollutants, Chemical

2010
Spatiotemporal distribution of pharmaceuticals in the Douro River estuary (Portugal).
    The Science of the total environment, 2010, Oct-15, Volume: 408, Issue:22

    Topics: Carbamazepine; Chromatography, Liquid; Diazepam; Environmental Monitoring; Fenofibrate; Pharmaceutical Preparations; Portugal; Propranolol; Risk Assessment; Rivers; Solid Phase Extraction; Sulfamethoxazole; Trimethoprim; Water Pollutants, Chemical

2010
An HPLC-UV method for the measurement of permeability of marker drugs in the Caco-2 cell assay.
    Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2011, Volume: 44, Issue:6

    Topics: Acyclovir; Caco-2 Cells; Carbamazepine; Cell Membrane Permeability; Chromatography, High Pressure Liquid; Humans; Hydrochlorothiazide; Intestinal Mucosa; Pharmaceutical Preparations; Propranolol; Ultraviolet Rays; Verapamil; Vinblastine

2011
The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal)--experimental assessment using a zebrafish embryo test.
    Environmental toxicology and pharmacology, 2011, Volume: 32, Issue:2

    Topics: Animals; Anti-Infective Agents; Anticonvulsants; Antihypertensive Agents; Carbamazepine; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Female; Fenofibrate; Heart Rate; Hypolipidemic Agents; Male; Pharmaceutical Preparations; Portugal; Propranolol; Random Allocation; Rivers; Sulfamethoxazole; Trimethoprim; Water Pollutants, Chemical; Zebrafish

2011
Fast investigations from biological matrices using CE--test of a blood-brain barrier model.
    Electrophoresis, 2012, Volume: 33, Issue:2

    Topics: Acetaminophen; Adsorption; Animals; Blood-Brain Barrier; Caffeine; Carbamazepine; Cell Culture Techniques; Cell Line; Chromatography, Micellar Electrokinetic Capillary; Cimetidine; Humans; Indomethacin; Limit of Detection; Models, Biological; Propranolol; Rats; Reproducibility of Results; Tissue Distribution

2012
Distribution and temporal evolution of pharmaceutically active compounds alongside sewage sludge treatment. Risk assessment of sludge application onto soils.
    Journal of environmental management, 2012, Jul-15, Volume: 102

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Carbamazepine; Clofibric Acid; Environmental Pollutants; Environmental Pollution; Estradiol; Gemfibrozil; Propranolol; Risk Assessment; Sewage; Soil; Spain; Time Factors

2012
The toxicity potential of pharmaceuticals found in the Douro River estuary (Portugal): evaluation of impacts on fish liver, by histopathology, stereology, vitellogenin and CYP1A immunohistochemistry, after sub-acute exposures of the zebrafish model.
    Environmental toxicology and pharmacology, 2012, Volume: 34, Issue:1

    Topics: Animals; Carbamazepine; Cytochrome P-450 CYP1A1; Female; Fenofibrate; Fish Proteins; Liver; Male; Portugal; Propranolol; Rivers; Sulfamethoxazole; Trimethoprim; Vitellogenins; Water Pollutants, Chemical; Zebrafish

2012
Phototransformation of wastewater-derived trace organic contaminants in open-water unit process treatment wetlands.
    Environmental science & technology, 2013, Oct-01, Volume: 47, Issue:19

    Topics: Atenolol; Carbamazepine; Carbonates; Cimetidine; Dimethylnitrosamine; Diuron; Estradiol; Hydroxyl Radical; Models, Chemical; Photolysis; Propranolol; Sulfamethoxazole; Sunlight; Waste Disposal, Fluid; Wastewater; Water Pollutants, Chemical; Wetlands

2013
Slow carbamazepine clearance in a nonadherent Malay woman with epilepsy and thyrotoxicosis.
    Therapeutic drug monitoring, 2014, Volume: 36, Issue:1

    Topics: Adult; Anticonvulsants; Antithyroid Agents; Carbamazepine; Carbimazole; Dose-Response Relationship, Drug; Drug Monitoring; Epilepsy; Female; Genetic Variation; Genotype; Humans; Hyperthyroidism; Malaysia; Medication Adherence; Multidrug Resistance-Associated Protein 2; Polymorphism, Genetic; Propranolol; Thyrotoxicosis

2014
Substrate-immobilized electrospun TiO2 nanofibers for photocatalytic degradation of pharmaceuticals: The effects of pH and dissolved organic matter characteristics.
    Water research, 2015, Dec-01, Volume: 86

    Topics: Carbamazepine; Catalysis; Cimetidine; Hydrogen-Ion Concentration; Nanofibers; Organic Chemicals; Photolysis; Propranolol; Titanium; Ultraviolet Rays; Water Pollutants, Chemical; Water Purification

2015
Low environmental levels of neuro-active pharmaceuticals alter phototactic behaviour and reproduction in Daphnia magna.
    Aquatic toxicology (Amsterdam, Netherlands), 2016, Volume: 170

    Topics: Animals; Behavior, Animal; Carbamazepine; Chromatography, High Pressure Liquid; Daphnia; Fluoxetine; Light; Propranolol; Reproduction; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Toxicity Tests; Water Pollutants, Chemical

2016
Derivation of water quality guidelines for priority pharmaceuticals.
    Environmental toxicology and chemistry, 2016, Volume: 35, Issue:7

    Topics: Animals; Aquatic Organisms; Carbamazepine; Diclofenac; Fluoxetine; Fresh Water; Guidelines as Topic; Pharmaceutical Preparations; Propranolol; Toxicity Tests, Chronic; Water Pollutants, Chemical; Water Quality

2016
Poly vinyl acetate and ammonio methacrylate copolymer as unconventional polymer blends increase the mechanical robustness of HPMC matrix tablets.
    International journal of pharmaceutics, 2017, Jan-10, Volume: 516, Issue:1-2

    Topics: Caffeine; Carbamazepine; Chemistry, Pharmaceutical; Drug Compounding; Drug Liberation; Excipients; Hypromellose Derivatives; Permeability; Polymers; Polyvinyls; Propranolol; Solubility; Tablets

2017
Development of potential candidate reference materials for drugs in bottom sediment, cod and herring tissues.
    Chemosphere, 2017, Volume: 169

    Topics: Acenocoumarol; Animals; Carbamazepine; Chromatography, Liquid; Environmental Monitoring; Fishes; Metoprolol; Naproxen; Propranolol; Reference Standards; Reproducibility of Results; Seafood; Tandem Mass Spectrometry; Water Pollutants, Chemical

2017
Investigating appearance and regulation of the MXR phenotype in early embryo stages of the Mediterranean mussel (Mytilus galloprovincialis).
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2017, Volume: 199

    Topics: Animals; Aquaculture; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Carbamazepine; Fertilization in Vitro; Fluorescent Dyes; Gene Expression Regulation, Developmental; Italy; Larva; Mediterranean Sea; Membrane Transport Modulators; Morphogenesis; Multidrug Resistance-Associated Proteins; Mytilus; Propranolol; Rhodamine 123; RNA, Messenger; Teratogens; Zygote

2017
Pharmaceutical Metabolism in Fish: Using a 3-D Hepatic In Vitro Model to Assess Clearance.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Animals; Atenolol; Biotransformation; Carbamazepine; Diazepam; Diclofenac; Drug Evaluation, Preclinical; Female; Kinetics; Liver; Metoprolol; Models, Animal; Oncorhynchus mykiss; Phenylbutazone; Propranolol; Tandem Mass Spectrometry; Water Pollutants, Chemical; Xenobiotics

2017
Sublethal metabolic responses to contaminant mixture toxicity in Daphnia magna.
    Environmental toxicology and chemistry, 2018, Volume: 37, Issue:9

    Topics: Alkanesulfonic Acids; Animals; Carbamazepine; Daphnia; Dose-Response Relationship, Drug; Fluorocarbons; Metabolome; Metabolomics; Propranolol; Wastewater; Water Pollutants, Chemical

2018
Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents.
    Journal of pharmacological sciences, 2018, Volume: 137, Issue:2

    Topics: Animals; Anticonvulsants; Antiparkinson Agents; Benzeneacetamides; Calcium Channel Blockers; Carbamazepine; Diazepam; Disease Models, Animal; Essential Tremor; Ethosuximide; Male; Mice, Inbred Strains; Nicotine; Phenobarbital; Propranolol; Pyridines; Valproic Acid

2018
Effect of electrolytes on the simultaneous electrochemical oxidation of sulfamethoxazole, propranolol and carbamazepine: behaviors, by-products and acute toxicity.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:7

    Topics: Boron; Carbamazepine; Diamond; Electrodes; Electrolytes; Gas Chromatography-Mass Spectrometry; Oxidation-Reduction; Propranolol; Sulfamethoxazole; Titanium; Toxicity Tests, Acute; Water Pollutants, Chemical

2019
Release Adjustment of Two Drugs with Different Solubility Combined in a Matrix Tablet.
    AAPS PharmSciTech, 2019, Mar-14, Volume: 20, Issue:4

    Topics: Adrenergic beta-Antagonists; Anticonvulsants; Carbamazepine; Cellulose; Hypromellose Derivatives; Propranolol; Solubility; Tablets

2019
In vitro biotransformation of pharmaceuticals and pesticides by trout liver S9 in the presence and absence of carbamazepine.
    Ecotoxicology and environmental safety, 2019, Nov-15, Volume: 183

    Topics: Animals; Biotransformation; Carbamazepine; Chromatography, Liquid; In Vitro Techniques; Liver; Pesticides; Pharmaceutical Preparations; Propranolol; Subcellular Fractions; Tandem Mass Spectrometry; Trout; Water Pollutants, Chemical

2019
Phenotypical and molecular changes induced by carbamazepine and propranolol on larval stages of Mytilus galloprovincialis.
    Chemosphere, 2019, Volume: 234

    Topics: Animals; Carbamazepine; Embryonic Development; Larva; Mytilus; Propranolol; Water Pollutants, Chemical

2019
Vanillin enhances the passive transport rate and absorption of drugs with moderate oral bioavailability in vitro and in vivo by affecting the membrane structure.
    Food & function, 2020, Jan-29, Volume: 11, Issue:1

    Topics: Acyclovir; Administration, Oral; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Antiviral Agents; Area Under Curve; Benzaldehydes; Biological Availability; Biological Transport; Caco-2 Cells; Carbamazepine; Diuretics; Humans; Hydrochlorothiazide; In Vitro Techniques; Intestinal Absorption; Male; Plant Extracts; Propranolol; Rats; Rats, Sprague-Dawley

2020
Quantification of porogen effect on the drug release from single- and multi-layered ethylcellulose coated pellets containing single or combined drugs.
    International journal of pharmaceutics, 2020, Mar-15, Volume: 577

    Topics: Caffeine; Carbamazepine; Cellulose; Chemistry, Pharmaceutical; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Models, Theoretical; Porosity; Propranolol; Solubility; Water

2020
Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats.
    Pharmacology research & perspectives, 2021, Volume: 9, Issue:5

    Topics: Animals; Antipyrine; Atenolol; Carbamazepine; Cell Membrane; Digoxin; Diltiazem; Diphenhydramine; Drug Elimination Routes; Gabapentin; Lamotrigine; Liver; Memantine; Membrane Transport Proteins; Microdialysis; Muscle, Skeletal; Ofloxacin; Pharmaceutical Preparations; Propranolol; Pyrilamine; Quinidine; Rats; Terfenadine

2021
Impact of dispersion time interval and particle size on release profiles of propranolol HCl and carbamazepines from microparticle blends system.
    Scientific reports, 2022, 06-20, Volume: 12, Issue:1

    Topics: Carbamazepine; Emulsions; Microspheres; Particle Size; Propranolol

2022