carbamazepine has been researched along with midazolam in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.44) | 18.7374 |
| 1990's | 4 (9.76) | 18.2507 |
| 2000's | 16 (39.02) | 29.6817 |
| 2010's | 17 (41.46) | 24.3611 |
| 2020's | 3 (7.32) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Adkison, KK; Humphreys, JE; Mahar Doan, KM; Polli, JW; Serabjit-Singh, CJ; Shampine, LJ; Webster, LO; Wring, SA | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F | 1 |
| Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Artursson, P; Mateus, A; Matsson, P | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S | 1 |
| Breimer, DD; de Boer, AG; van Hoogdalem, E | 1 |
| Franceschetti, S; Hamon, B; Heinemann, U; Konnerth, A; Yaari, Y | 1 |
| Slater, BL | 1 |
| Backman, JT; Laaksovirta, H; Neuvonen, PJ; Ojala, M; Olkkola, KT | 1 |
| Dreier, JP; Heinemann, U; Zhang, CL | 1 |
| Komatsu, K; Ono, A; Sawaishi, Y; Takada, G; Yano, T | 1 |
| Carlisle, RD; Spiller, HA | 1 |
| Rekling, JC | 1 |
| de Kanter, R; Groothuis, G; Martignoni, M | 1 |
| Johnson, TN; Rostami-Hodjegan, A; Tucker, GT | 1 |
| Cederberg, J; Dahl, ML; Karlsson, MO; Magnusson, MO; Sandström, R | 1 |
| Bodmer, M; Grignaschi, N; Haschke, M; Krähenbühl, S; Kummer, O; Link, B; Ruegg, S | 1 |
| Aohara, F; Emoto, C; Fujimura, Y; Hanioka, N; Iwasaki, K; Maekawa, K; Narimatsu, S; Niwa, T; Saito, Y; Sawada, J; Yoshimura, T | 1 |
| Aohara, F; Fujimura, Y; Harakawa, N; Hasegawa, R; Katori, N; Kim, SR; Maekawa, K; Naito, M; Niwa, T; Okuda, H; Sai, K; Saito, Y; Sawada, J; Tohkin, M; Yoshimura, T | 1 |
| Hayashi, M; Shou, M; Skiles, GL; Xu, Y; Zhou, Y | 1 |
| Atkins, WM; Halpert, JR; Nelson, SD; Roberts, AG; Thummel, KT; Yang, J | 1 |
| Srinivas, NR | 1 |
| Chow, E; Gane, J; Jeffrey, M; Lang, M; Wu, C; Zhang, L | 1 |
| Delalande, O; Dvorak, J; Jahodova, A; Komarek, V; Kršek, P; Kyncl, M; Tichy, M; Vydrova, R | 1 |
| El Hamd, MA; Ikeda, R; Kawakami, S; Nakashima, K; Wada, M | 1 |
| Hayashi, T; Higuchi, H; Ishii-Maruhama, M; Maeda, S; Miyawaki, T; Tomoyasu, Y | 1 |
| Chen, X; Durisic, N; Keramidas, A; Lynch, JW | 1 |
| Araya, EI; Baggio, DF; Chichorro, JG; Koren, LO; Schwarting, RKW | 1 |
| Abraham, TL; Bedwell, DW; Hall, SD; Hansen, K; Rougée, LRA | 1 |
2 review(s) available for carbamazepine and midazolam
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Pharmacokinetics of rectal drug administration, Part I. General considerations and clinical applications of centrally acting drugs.
Topics: Administration, Rectal; Antiemetics; Atropine; Carbamazepine; Clonazepam; Delayed-Action Preparations; Diazepam; Flunitrazepam; Humans; Hydromorphone; Intestinal Absorption; Methadone; Methohexital; Midazolam; Morphine; Pharmacokinetics; Phenobarbital; Valproic Acid | 1991 |
39 other study(ies) available for carbamazepine and midazolam
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Passive permeability and P-glycoprotein-mediated efflux differentiate central nervous system (CNS) and non-CNS marketed drugs.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Cell Membrane Permeability; Central Nervous System Agents; Dogs; Drug Delivery Systems; Permeability; Pharmaceutical Preparations | 2002 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery.
Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats | 2007 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method.
Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution | 2011 |
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2014 |
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones | 2021 |
Effects of anticonvulsants on spontaneous epileptiform activity which develops in the absence of chemical synaptic transmission in hippocampal slices.
Topics: Animals; Anticonvulsants; Benzodiazepines; Carbamazepine; Cell Membrane Permeability; Epilepsy; Hippocampus; In Vitro Techniques; Ion Channels; Midazolam; Phenobarbital; Phenytoin; Rats; Valproic Acid | 1985 |
Propofol and epilepsy.
Topics: Aged; Aged, 80 and over; Anesthetics, Intravenous; Anticonvulsants; Carbamazepine; Epilepsy, Absence; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Midazolam; Propofol; Thiopental | 1995 |
Concentrations and effects of oral midazolam are greatly reduced in patients treated with carbamazepine or phenytoin.
Topics: Administration, Oral; Adult; Carbamazepine; Drug Interactions; Enzyme Induction; Epilepsy; Female; Flicker Fusion; Half-Life; Humans; Male; Midazolam; Middle Aged; Phenytoin; Sleep | 1996 |
Phenytoin, phenobarbital, and midazolam fail to stop status epilepticus-like activity induced by low magnesium in rat entorhinal slices, but can prevent its development.
Topics: Animals; Anticonvulsants; Carbamazepine; Culture Techniques; Dose-Response Relationship, Drug; Drug Resistance; Electroencephalography; Entorhinal Cortex; Magnesium; Midazolam; Phenobarbital; Phenytoin; Rats; Rats, Wistar; Status Epilepticus | 1998 |
[A case of carbamazepine intoxication with alpha coma and status epilepticus].
Topics: Adolescent; Carbamazepine; Charcoal; Coma; Electroencephalography; Female; Gastric Lavage; Humans; Midazolam; Status Epilepticus; Treatment Outcome | 2001 |
Status epilepticus after massive carbamazepine overdose.
Topics: Adolescent; Anticonvulsants; Carbamazepine; Drug Overdose; Fatal Outcome; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Male; Midazolam; Status Epilepticus; Tachycardia; Treatment Failure | 2002 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
Comparison of mouse and rat cytochrome P450-mediated metabolism in liver and intestine.
Topics: Animals; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydroxytestosterones; In Vitro Techniques; Intestinal Mucosa; Intestines; Ketoconazole; Liver; Male; Membrane Proteins; Mice; Mice, Nude; Microsomes; Midazolam; Oxidoreductases; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substrate Specificity | 2006 |
Prediction of the clearance of eleven drugs and associated variability in neonates, infants and children.
Topics: Algorithms; Caffeine; Carbamazepine; Child; Computer Simulation; Humans; Infant; Infant, Newborn; Metabolic Clearance Rate; Midazolam; Models, Biological; Monte Carlo Method; Software | 2006 |
Pharmacodynamics of carbamazepine-mediated induction of CYP3A4, CYP1A2, and Pgp as assessed by probe substrates midazolam, caffeine, and digoxin.
Topics: Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeine; Carbamazepine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP3A; Digoxin; Enzyme Induction; Humans; Male; Metabolic Clearance Rate; Midazolam; Middle Aged; Substrate Specificity | 2008 |
Pharmacokinetics of midazolam and metabolites in a patient with refractory status epilepticus treated with extraordinary doses of midazolam.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Half-Life; Humans; Metabolic Clearance Rate; Midazolam; Middle Aged; Phenytoin; Status Epilepticus | 2008 |
Functional characterization of CYP3A4.16: catalytic activities toward midazolam and carbamazepine.
Topics: Alleles; Animals; Carbamazepine; Cells, Cultured; Cytochrome P-450 CYP3A; Humans; Hydroxylation; Kinetics; Microsomes; Midazolam; NADPH-Ferrihemoprotein Reductase; Recombinant Proteins; Spodoptera; Substrate Specificity | 2009 |
CYP3A4*16 and CYP3A4*18 alleles found in East Asians exhibit differential catalytic activities for seven CYP3A4 substrate drugs.
Topics: Alleles; Animals; Asia, Eastern; Atorvastatin; Biocatalysis; Camptothecin; Carbamazepine; Cytochrome P-450 CYP3A; Docetaxel; Heptanoic Acids; Humans; Irinotecan; Midazolam; Models, Molecular; Paclitaxel; Pyrroles; Spodoptera; Substrate Specificity; Taxoids; Terfenadine | 2010 |
Simulation of clinical drug-drug interactions from hepatocyte CYP3A4 induction data and its potential utility in trial designs.
Topics: Area Under Curve; Carbamazepine; Cytochrome P-450 CYP3A; Drug Interactions; Enzyme Induction; Hepatocytes; Humans; Midazolam; Nifedipine; Phenobarbital; Rifampin; Simvastatin; Substrate Specificity | 2011 |
The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4.
Topics: Algorithms; Anticonvulsants; Biocatalysis; Carbamazepine; Catalytic Domain; Computer Simulation; Cytochrome P-450 CYP3A; Humans; Hydroxylation; Hypnotics and Sedatives; Kinetics; Ligands; Midazolam; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Recombinant Proteins | 2011 |
Is pomegranate juice a potential perpetrator of clinical drug-drug interactions? Review of the in vitro, preclinical and clinical evidence.
Topics: Animals; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Aryl Hydrocarbon Hydroxylases; Beverages; Buspirone; Caco-2 Cells; Calcium Channel Blockers; Carbamazepine; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Evaluation, Preclinical; Drug Interactions; Flurbiprofen; Food-Drug Interactions; Humans; Hypnotics and Sedatives; Hypoglycemic Agents; Lythraceae; Midazolam; Nitrendipine; Tolbutamide; Triazolam | 2013 |
Novel anticonvulsive effects of progesterone in a mouse model of hippocampal electrical kindling.
Topics: Action Potentials; Animals; Anticonvulsants; Berberine Alkaloids; Carbamazepine; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Combinations; Electrodes, Implanted; Finasteride; Hippocampus; In Vitro Techniques; Kindling, Neurologic; Male; Mice; Mice, Inbred C57BL; Midazolam; Picrotoxin; Progesterone; Seizures | 2014 |
Peri-ictal headache due to epileptiform activity in a disconnected hemisphere.
Topics: Anticonvulsants; Brain; Carbamazepine; Child, Preschool; Electroencephalography; Epilepsy; Female; Functional Laterality; Headache; Hemispherectomy; Humans; Midazolam; Neurosurgical Procedures; Seizures | 2014 |
Validation of an LC-MS/MS Method for the Determination of Propofol, Midazolam, and Carbamazepine in Rat Plasma: Application to Monitor Their Concentrations Following Co-administration.
Topics: Animals; Carbamazepine; Chromatography, High Pressure Liquid; Chromatography, Liquid; Drug Therapy, Combination; Hypnotics and Sedatives; Midazolam; Plasma; Propofol; Rats; Reproducibility of Results; Solid Phase Extraction; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2015 |
Effect of carbamazepine or phenytoin therapy on blood level of intravenously administered midazolam: a prospective cohort study.
Topics: Administration, Intravenous; Adult; Anticonvulsants; Carbamazepine; Cohort Studies; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Midazolam; Phenytoin; Prospective Studies; Young Adult | 2016 |
Inhibitory synapse deficits caused by familial α1 GABA
Topics: Animals; Anticonvulsants; Carbamazepine; Cerebral Cortex; Coculture Techniques; Epilepsy; HEK293 Cells; Humans; Hydroxamic Acids; Inhibitory Postsynaptic Potentials; Midazolam; Neural Inhibition; Neurons; Patch-Clamp Techniques; Protein Folding; Rats; Receptors, GABA-A; Synapses; Temperature; Vorinostat | 2017 |
Trigeminal neuropathic pain reduces 50-kHz ultrasonic vocalizations in rats, which are restored by analgesic drugs.
Topics: Analgesics; Animals; Carbamazepine; Hyperalgesia; Lidocaine; Male; Midazolam; Neuralgia; Rats; Trigeminal Neuralgia; Vocalization, Animal | 2022 |
Impact of Heterotropic Allosteric Modulation on the Time-Dependent Inhibition of Cytochrome P450 3A4.
Topics: Carbamazepine; Clarithromycin; Cytochrome P-450 CYP3A; Drug Interactions; Humans; Microsomes, Liver; Midazolam; Troleandomycin | 2023 |