carbamazepine and lacosamide

carbamazepine has been researched along with lacosamide in 53 studies

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (5.66)29.6817
2010's33 (62.26)24.3611
2020's17 (32.08)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Filipek, B; Kamiński, K; Kieć-Kononowicz, K; Latacz, G; Obniska, J; Rapacz, A; Łuszczki, JJ1
Andres-Mach, M; Kamiński, K; Kieć-Kononowicz, K; Latacz, G; Rapacz, A; Zagaja, M; Łuszczki, JJ1
Abram, M; Andres-Mach, M; Kamiński, K; Obniska, J; Rapacz, A; Zagaja, M; Łuszczki, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Filipek, B; Kamiński, K; Obniska, J; Rapacz, A1
Bai, Y; Chen, X; Cuan, Y; Ding, Y; Fan, TP; He, X; Jia, P; Li, B; Li, Y; Liang, J; Liao, S; Meng, X; Qin, F; Shan, G; Sun, Y; Wang, S; Wei, X; Wu, B; Xiao, C; Xie, J; Yu, J; Zeng, M; Zhang, Q; Zhang, Y; Zhao, Y; Zhao, Z; Zheng, X; Zhu, Z1
Errington, AC; Lees, G; Stöhr, T1
Cummins, TR; Heers, C; Sheets, PL; Stoehr, T1
Cawello, W; Eggert-Formella, A; Nickel, B1
Arnaboldi, M; Belcastro, V; Prontera, P; Taborelli, A1
Albus, C; Beck, H; Isom, L; Niespodziany, I; Opitz, T; Uebachs, M; Wolff, C1
Fadda, V; Giovannelli, F; Maratea, D; Verrotti, A; Zaccara, G1
Deuschl, G; Lang, N; Peckolt, H; Rothkegel, H1
Jin, DI; Kang, JW; Lee, JE; Lee, SH; Lin, T1
Duncan, JS; Markoula, S; Patsalos, PN; Ratnaraj, N; Sander, JW; Teotonio, R1
Bonifácio, MJ; Hebeisen, S; Loureiro, AI; Palma, N; Pires, N; Soares-da-Silva, P; Spanswick, D; Whyment, A1
Horváth, A; Kamondi, A; Szűcs, A1
Kumar, D; Laurenza, A; Meador, KJ; Piña-Garza, JE; Wesnes, KA; Yang, H1
Brandt, C; De Backer, M; Dedeken, P; Eckhardt, K; Elger, CE; Elmoufti, S; Rademacher, M; Tennigkeit, F1
Borghs, S; Boyd, A; Byrnes, W; De Backer, M; Dedeken, P; Dilley, D; Echauz, J; Korb, P; LaRoche, S; Loring, DW; Meador, KJ; Story, T; Velez-Ruiz, N; Webster, E1
Andres-Mach, M; Florek-Łuszczki, M; Patrzylas, P; Pyrka, D; Skalicka-Woźniak, K; Szpringer, M; Zagaja, M; Żółkowska, D; Łuszczki, JJ1
Baulac, M; Brock, M; De Backer, M; Li, T; Rosenow, F; Terada, K; Toledo, M; Werhahn, KJ1
Brigo, F1
Bean, BP; Jo, S1
Chan, EL; Chan, I; Chang, RS; Fong, GC; Fong, JK; Fung, BB; Fung, EL; Leung, H; Lui, CH; Poon, TL; Siu, D; Wong, HT; Yeung, E; Yung, AW; Zhu, CX1
Tikhonov, DB; Zhorov, BS1
Baheerathan, A; Brownlee, WJ; Chard, DT; Rugg-Gunn, F; Trip, SA1
Abaroa, L; Alejandro Rodríguez-Quiroga, S; Arakaki, T; Garretto, NS; Melamud, L; Villa, AM1
Cantero-Lozano, D; Garces-Anton, E; Garces-Redondo, M; Garrido-Fernandez, A; Lopez-Bravo, A; Marin-Gracia, M; Navarro-Perez, MP; Santos-Lasaosa, S1
Rocha, JF; Soares-da-Silva, P; Trinka, E1
Brigo, F; Lattanzi, S1
Alfano, G; Mangiardi, M1
Ben-Menachem, E; Biton, V; Brock, M; De Backer, M; Gasalla, T; Grebe, HP; Jensen, L; Li, T; Steiniger-Brach, B; Terada, K1
Chellun, D; De Backer, M; Dimova, S; Gasalla, T; Schmitz, B; Zhang, Y1
Bozorg, A; Brandt, C; Dimova, S; Ferrò, B; Holmes, GL; Kälviäinen, R; Rosenow, F; Steiniger-Brach, B; Zhang, Y1
Kaimovsky, IL; Mkrtchyan, VR1
Goji, A; Kagami, S; Mori, T; Tayama, T; Toda, Y1
Furukawa, G; Ishihara, N; Negishi, Y; Okumura, A; Takeuchi, T1
Hayashi, T; Noguchi, Y; Tachi, T; Takaoka, M; Teramachi, H1
Diomedi, M; Izzi, F; Lauretti, B; Liguori, C; Mercuri, NB; Pisani, A; Placidi, F; Posca, I; Rocchi, C1
Araki, Y; Fukushima, Y; Imai, K; Kagawa, Y; Takahashi, Y; Terada, K; Yamamoto, Y1
Chellun, D; De Backer, M; Dimova, S; Mintzer, S; Roebling, R; Steiniger-Brach, B; Zhang, Y1
Chang, YP; Huang, LC; Li, KY; Yang, YH1
Adamovich-Zeitlin, RH; Camp, EJ; Gross, RE; Jobst, BC; Kahana, MJ; Lega, BC; MacKenzie, TA; Meisenhelter, S; Quon, RJ; Song, Y; Sperling, MR; Steimel, SA; Testorf, ME1
Panda, PK; Sharawat, IK1
Benjamin, RN; Mathew, V; Mathews, DA; Miraclin, TA; Moorthy, M; Naresh, K; Prabhakar, AT; Prakash, JAJ; Sivadasan, A1
Birnbaum, AK; Gerard, E; Kalayjian, L; Karanam, A; Matthews, A; McElrath, TM; Meador, KJ; Pennell, PB; Penovich, P1
Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T1
Eguchi, Y; Ishikawa, N; Izumo, H; Kobayashi, Y; Okada, S; Tateishi, Y1
Fan, X; Huang, G; Huang, J; Jin, X; Li, J; Pan, X; Wang, K; Wu, Q; Yan, N1
Chellun, D; Dimova, S; Elmoufti, S; Floricel, F; Kubota, Y; O'Brien, TJ; Terada, K1

Reviews

5 review(s) available for carbamazepine and lacosamide

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Neurological adverse events of new generation sodium blocker antiepileptic drugs. Meta-analysis of randomized, double-blinded studies with eslicarbazepine acetate, lacosamide and oxcarbazepine.
    Seizure, 2013, Volume: 22, Issue:7

    Topics: Acetamides; Anticonvulsants; Ataxia; Carbamazepine; Dibenzazepines; Diplopia; Dizziness; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Lacosamide; Nervous System Diseases; Oxcarbazepine; Randomized Controlled Trials as Topic; Risk Assessment; Sodium Channel Blockers; Treatment Outcome

2013
An update of the Hong Kong Epilepsy Guideline: consensus statement on the use of antiepileptic drugs in Hong Kong.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2017, Volume: 23, Issue:1

    Topics: Acetamides; Anticonvulsants; Carbamazepine; Consensus; Drugs, Generic; Epilepsy; Hong Kong; Humans; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Piracetam; Practice Guidelines as Topic; Societies, Medical; Triazines

2017
The effects of lacosamide on cognitive function and psychiatric profiles in patients with epilepsy.
    Epilepsy & behavior : E&B, 2020, Volume: 113

    Topics: Adult; Affect; Anticonvulsants; Carbamazepine; Cognition; Epilepsy; Humans; Lacosamide; Lamotrigine; Nitriles; Pyridones; Quality of Life; Topiramate

2020
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
    Epileptic disorders : international epilepsy journal with videotape, 2022, 12-01, Volume: 24, Issue:6

    Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide

2022

Trials

12 trial(s) available for carbamazepine and lacosamide

ArticleYear
No pharmacokinetic interaction between lacosamide and carbamazepine in healthy volunteers.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:4

    Topics: Acetamides; Adolescent; Adult; Carbamazepine; Drug Interactions; Humans; Lacosamide; Male; Middle Aged; Young Adult

2010
Effects of lacosamide and carbamazepine on human motor cortex excitability: a double-blind, placebo-controlled transcranial magnetic stimulation study.
    Seizure, 2013, Volume: 22, Issue:9

    Topics: Acetamides; Adult; Analysis of Variance; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy; Evoked Potentials, Motor; Female; Humans; Lacosamide; Male; Motor Cortex; Transcranial Magnetic Stimulation; Young Adult

2013
Cognitive effects of adjunctive perampanel for partial-onset seizures: A randomized trial.
    Epilepsia, 2016, Volume: 57, Issue:2

    Topics: Acetamides; Adolescent; Anticonvulsants; Attention; Carbamazepine; Child; Cognition; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Female; Fructose; Humans; Lacosamide; Lamotrigine; Levetiracetam; Male; Memory, Short-Term; Neuropsychological Tests; Nitriles; Oxcarbazepine; Piracetam; Pyridones; Topiramate; Treatment Outcome; Triazines; Valproic Acid

2016
Changes in hormone and lipid levels in male patients with focal seizures when switched from carbamazepine to lacosamide as adjunctive treatment to levetiracetam: A small phase IIIb, prospective, multicenter, open-label trial.
    Epilepsy & behavior : E&B, 2016, Volume: 62

    Topics: Acetamides; Adult; Anticonvulsants; Carbamazepine; Cholesterol; Dose-Response Relationship, Drug; Drug Substitution; Drug Therapy, Combination; Epilepsies, Partial; Humans; Lacosamide; Levetiracetam; Lipids; Lipoproteins, LDL; Male; Piracetam; Progesterone; Prospective Studies; Sex Hormone-Binding Globulin; Testosterone; Thyroxine; Treatment Outcome

2016
Randomized double-blind comparison of cognitive and EEG effects of lacosamide and carbamazepine.
    Epilepsy & behavior : E&B, 2016, Volume: 62

    Topics: Acetamides; Adolescent; Adult; Anticonvulsants; Brain; Carbamazepine; Cognition; Cross-Over Studies; Double-Blind Method; Electroencephalography; Female; Humans; Lacosamide; Male; Middle Aged; Neuropsychological Tests; Young Adult

2016
Efficacy, safety, and tolerability of lacosamide monotherapy versus controlled-release carbamazepine in patients with newly diagnosed epilepsy: a phase 3, randomised, double-blind, non-inferiority trial.
    The Lancet. Neurology, 2017, Volume: 16, Issue:1

    Topics: Acetamides; Adolescent; Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Delivery Systems; Epilepsy; Female; Follow-Up Studies; Humans; Kaplan-Meier Estimate; Lacosamide; Male; Middle Aged; Treatment Outcome; Young Adult

2017
A clinical efficacy experience of Lacosamide on sleep quality in patients with Nocturnal Frontal Lobe Epilepsy (NFLE).
    Acta bio-medica : Atenei Parmensis, 2018, 10-08, Volume: 89, Issue:3

    Topics: Adult; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Substitution; Epilepsy, Frontal Lobe; Female; Humans; Lacosamide; Male; Nocturnal Paroxysmal Dystonia; Oxcarbazepine; Voltage-Gated Sodium Channel Blockers

2018
Long-term safety and efficacy of lacosamide and controlled-release carbamazepine monotherapy in patients with newly diagnosed epilepsy.
    Epilepsia, 2019, Volume: 60, Issue:12

    Topics: Adult; Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Dizziness; Double-Blind Method; Epilepsy; Female; Headache; Humans; Lacosamide; Male; Middle Aged; Time Factors; Treatment Outcome; Young Adult

2019
Tolerability and efficacy of lacosamide and controlled-release carbamazepine monotherapy in patients with newly diagnosed epilepsy and concomitant psychiatric conditions: Post hoc analysis of a prospective, randomized, double-blind trial.
    Epilepsy research, 2020, Volume: 159

    Topics: Adult; Aged; Anticonvulsants; Anxiety; Carbamazepine; Delayed-Action Preparations; Depression; Double-Blind Method; Epilepsy; Female; Humans; Lacosamide; Male; Middle Aged; Sleep Initiation and Maintenance Disorders; Treatment Outcome

2020
Lacosamide in patients with epilepsy of cerebrovascular etiology.
    Acta neurologica Scandinavica, 2020, Volume: 141, Issue:6

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Cerebrovascular Disorders; Dose-Response Relationship, Drug; Double-Blind Method; Epilepsy; Female; Humans; Lacosamide; Male; Middle Aged; Treatment Outcome; Young Adult

2020
Effects of lacosamide and carbamazepine on lipids in a randomized trial.
    Epilepsia, 2020, Volume: 61, Issue:12

    Topics: Anticonvulsants; Carbamazepine; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Double-Blind Method; Epilepsy; Humans; Lacosamide; Lipids; Triglycerides

2020
Efficacy and tolerability of lacosamide and controlled-release carbamazepine monotherapy in patients with newly diagnosed temporal lobe epilepsy: Post hoc analysis of a randomized, double-blind trial.
    Seizure, 2023, Volume: 112

    Topics: Adult; Anticonvulsants; Benzodiazepines; Carbamazepine; Delayed-Action Preparations; Double-Blind Method; Epilepsy, Temporal Lobe; Humans; Lacosamide; Seizures; Treatment Outcome

2023

Other Studies

36 other study(ies) available for carbamazepine and lacosamide

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Design, synthesis and biological evaluation of new hybrid anticonvulsants derived from N-benzyl-2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2,5-dioxopyrrolidin-1-yl)butanamide derivatives.
    Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10

    Topics: Amides; Animals; Anticonvulsants; Benzylamines; Convulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Electroshock; Humans; Imidazoles; Male; Mice; Microsomes, Liver; Molecular Structure; Motor Activity; Pentylenetetrazole; Propionates; Pyrrolidines; Rotarod Performance Test; Seizures; Small Molecule Libraries; Structure-Activity Relationship

2015
Design, synthesis, and anticonvulsant activity of new hybrid compounds derived from 2-(2,5-dioxopyrrolidin-1-yl)propanamides and 2-(2,5-dioxopyrrolidin-1-yl)butanamides.
    Journal of medicinal chemistry, 2015, Jul-09, Volume: 58, Issue:13

    Topics: Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Electroshock; HEK293 Cells; Humans; Mice; Models, Molecular; Molecular Structure; Motor Activity; Piperazines; Seizures; Structure-Activity Relationship; Succinimides

2015
New hybrid molecules with anticonvulsant and antinociceptive activity derived from 3-methyl- or 3,3-dimethyl-1-[1-oxo-1-(4-phenylpiperazin-1-yl)propan-2-yl]pyrrolidine-2,5-diones.
    Bioorganic & medicinal chemistry, 2016, Feb-15, Volume: 24, Issue:4

    Topics: Analgesics; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Injections, Intraperitoneal; Mice; Molecular Structure; Pain; Pain Measurement; Pentylenetetrazole; Piperazines; Pyrrolidinones; Seizures

2016
Design, synthesis and anticonvulsant activity of new hybrid compounds derived from N-phenyl-2-(2,5-dioxopyrrolidin-1-yl)-propanamides and -butanamides.
    Bioorganic & medicinal chemistry, 2016, 07-01, Volume: 24, Issue:13

    Topics: Amides; Animals; Anticonvulsants; Calcium Channels; Drug Design; Humans; Injections, Intraperitoneal; Mice; Molecular Structure; Neurons; Pyrrolidines; Seizures

2016
Polygala tenuifolia-Acori tatarinowii herbal pair as an inspiration for substituted cinnamic α-asaronol esters: Design, synthesis, anticonvulsant activity, and inhibition of lactate dehydrogenase study.
    European journal of medicinal chemistry, 2019, Dec-01, Volume: 183

    Topics: Allosteric Regulation; Animals; Anisoles; Anticonvulsants; Carbamazepine; Cinnamates; Dioxolanes; Drug Design; Drugs, Chinese Herbal; Esters; Humans; L-Lactate Dehydrogenase; Medicine, Chinese Traditional; Mice; Molecular Structure; Neuralgia; Polygala; Receptors, GABA-A; Structure-Activity Relationship; Valproic Acid

2019
Stereoselective effects of the novel anticonvulsant lacosamide against 4-AP induced epileptiform activity in rat visual cortex in vitro.
    Neuropharmacology, 2006, Volume: 50, Issue:1

    Topics: 2-Amino-5-phosphonovalerate; 4-Aminopyridine; 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetamides; Animals; Anticonvulsants; Carbamazepine; Convulsants; Electrophysiology; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Space; Female; In Vitro Techniques; Lacosamide; Male; Membrane Potentials; Patch-Clamp Techniques; Phenobarbital; Picrotoxin; Potassium Channel Blockers; Prohibitins; Rats; Rats, Sprague-Dawley; Synaptic Transmission; Visual Cortex

2006
Differential block of sensory neuronal voltage-gated sodium channels by lacosamide [(2R)-2-(acetylamino)-N-benzyl-3-methoxypropanamide], lidocaine, and carbamazepine.
    The Journal of pharmacology and experimental therapeutics, 2008, Volume: 326, Issue:1

    Topics: Acetamides; Animals; Carbamazepine; Cell Line; Cells, Cultured; Humans; Lacosamide; Lidocaine; Male; Neurons, Afferent; Rats; Rats, Sprague-Dawley; Sodium Channel Blockers; Sodium Channels

2008
Lacosamide: new drug. Refractory partial epilepsy: optimise existing combinations.
    Prescrire international, 2009, Volume: 18, Issue:103

    Topics: Acetamides; Anticonvulsants; Atrioventricular Block; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Epilepsies, Partial; Europe; Humans; Lacosamide; Randomized Controlled Trials as Topic

2009
Induction of epileptic negative myoclonus by addition of lacosamide to carbamazepine.
    Epilepsy & behavior : E&B, 2011, Volume: 20, Issue:3

    Topics: Acetamides; Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lacosamide

2011
Loss of β1 accessory Na+ channel subunits causes failure of carbamazepine, but not of lacosamide, in blocking high-frequency firing via differential effects on persistent Na+ currents.
    Epilepsia, 2012, Volume: 53, Issue:11

    Topics: Acetamides; Action Potentials; Animals; Carbamazepine; Cells, Cultured; Lacosamide; Mice; Mice, Congenic; Mice, Inbred C57BL; Mice, Knockout; Neurons; Protein Subunits; Voltage-Gated Sodium Channel beta-1 Subunit

2012
Teratogenic potential of antiepileptic drugs in the zebrafish model.
    BioMed research international, 2013, Volume: 2013

    Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Ethosuximide; Female; Fructose; Humans; Lacosamide; Lamotrigine; Levetiracetam; Piracetam; Pregnancy; Teratogenesis; Topiramate; Triazines; United States; Valproic Acid; Zebrafish

2013
Lacosamide serum concentrations in adult patients with epilepsy: the influence of gender, age, dose, and concomitant antiepileptic drugs.
    Therapeutic drug monitoring, 2014, Volume: 36, Issue:4

    Topics: Acetamides; Adult; Aged; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Enzyme Induction; Epilepsy; Female; Humans; Lacosamide; Male; Middle Aged; Phenytoin; Retrospective Studies; Seizures; Valproic Acid

2014
Eslicarbazepine and the enhancement of slow inactivation of voltage-gated sodium channels: a comparison with carbamazepine, oxcarbazepine and lacosamide.
    Neuropharmacology, 2015, Volume: 89

    Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Cell Line, Tumor; Dibenzazepines; Dose-Response Relationship, Drug; Hippocampus; Lacosamide; Male; Mice; Organ Culture Techniques; Oxcarbazepine; Time Factors; Voltage-Gated Sodium Channels

2015
[The efficacy of lacosamide in relation to antiepileptic drug history. Clinical experiences in adult partial epilepsy].
    Ideggyogyaszati szemle, 2015, Jan-30, Volume: 68, Issue:1-2

    Topics: Acetamides; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Drug Resistance; Drug Therapy, Combination; Epilepsies, Partial; Female; Follow-Up Studies; Humans; Lacosamide; Male; Middle Aged; Oxcarbazepine; Recurrence; Retrospective Studies; Treatment Outcome

2015
Influence of xanthotoxin (8-methoxypsoralen) on the anticonvulsant activity of various novel antiepileptic drugs against maximal electroshock-induced seizures in mice.
    Fitoterapia, 2016, Volume: 115

    Topics: Acetamides; Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Electroshock; Fructose; Lacosamide; Lamotrigine; Male; Methoxsalen; Mice; Oxcarbazepine; Pregabalin; Seizures; Topiramate; Triazines

2016
Lacosamide monotherapy for newly diagnosed epilepsy.
    The Lancet. Neurology, 2017, Volume: 16, Issue:1

    Topics: Carbamazepine; Delayed-Action Preparations; Double-Blind Method; Epilepsy; Humans; Lacosamide

2017
Lacosamide Inhibition of Nav1.7 Voltage-Gated Sodium Channels: Slow Binding to Fast-Inactivated States.
    Molecular pharmacology, 2017, Volume: 91, Issue:4

    Topics: Acetamides; Carbamazepine; HEK293 Cells; Humans; Ion Channel Gating; Lacosamide; Membrane Potentials; NAV1.7 Voltage-Gated Sodium Channel; Time Factors

2017
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants.
    The Journal of general physiology, 2017, Apr-03, Volume: 149, Issue:4

    Topics: Acetamides; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Anticonvulsants; Benzhydryl Compounds; Binding Sites; Carbamazepine; Cocaine; Humans; Lacosamide; Lamotrigine; Lidocaine; Molecular Docking Simulation; NAV1.4 Voltage-Gated Sodium Channel; Phenols; Phenytoin; Piperazines; Protein Binding; Pyrimidines; Quinidine; Sodium Channel Blockers; Triazines

2017
Neuromyelitis optica spectrum disorder related tonic spasms responsive to lacosamide.
    Multiple sclerosis and related disorders, 2017, Volume: 13

    Topics: Acetamides; Adult; Anticonvulsants; Carbamazepine; Female; Humans; Lacosamide; Neuromyelitis Optica; Spasm; Treatment Outcome

2017
Commentary on: Neuromyelitis optica spectrum disorder related tonic spams responsive to lacosamide.
    Multiple sclerosis and related disorders, 2017, Volume: 17

    Topics: Acetamides; Carbamazepine; Humans; Lacosamide; Neuromyelitis Optica

2017
[Lacosamide associated with high-degree block in a patient with trigeminal neuralgia].
    Revista de neurologia, 2018, Mar-16, Volume: 66, Issue:6

    Topics: Aged; Anticonvulsants; Atrioventricular Block; Bradycardia; Carbamazepine; Cardiopulmonary Resuscitation; Combined Modality Therapy; Contraindications, Drug; Dibenzazepines; Drug Substitution; Electrocardiography; Heart Arrest; Humans; Lacosamide; Male; Nerve Block; Nociceptors; Pacemaker, Artificial; Trigeminal Neuralgia; Voltage-Gated Sodium Channel Blockers

2018
Response: Comparing the dosages of lacosamide, eslicarbazepine acetate, and controlled-release carbamazepine in noninferiority epilepsy monotherapy trials: How much "fair" is "fair".
    Epilepsia, 2018, Volume: 59, Issue:4

    Topics: Acetamides; Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Dibenzazepines; Epilepsy; Humans; Lacosamide

2018
Comparing the dosages of lacosamide, eslicarbazepine acetate, and controlled-release carbamazepine in noninferiority epilepsy monotherapy trials: How much "fair" is "fair"?
    Epilepsia, 2018, Volume: 59, Issue:4

    Topics: Acetamides; Anticonvulsants; Carbamazepine; Delayed-Action Preparations; Dibenzazepines; Epilepsy; Humans; Lacosamide

2018
[Pharmacoeconomic aspects of monotherapy of focal epilepsy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2019, Volume: 119, Issue:11. Vyp. 2

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Cost-Benefit Analysis; Economics, Pharmaceutical; Epilepsies, Partial; Humans; Lacosamide; Lamotrigine; Oxcarbazepine; Retrospective Studies

2019
Improvement of epilepsy with lacosamide in a patient with ring chromosome 20 syndrome.
    Brain & development, 2020, Volume: 42, Issue:6

    Topics: Anticonvulsants; Carbamazepine; Child; Electroencephalography; Epilepsy; Humans; Lacosamide; Lamotrigine; Levetiracetam; Male; Ring Chromosomes; Seizures; Treatment Outcome; Valproic Acid

2020
Lacosamide for children with paroxysmal kinesigenic dyskinesia.
    Brain & development, 2020, Volume: 42, Issue:8

    Topics: Adolescent; Carbamazepine; Child; Dystonia; Female; Humans; Lacosamide; Male; Membrane Proteins; Mutation; Nerve Tissue Proteins; Retrospective Studies

2020
Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database.
    Epilepsia, 2020, Volume: 61, Issue:9

    Topics: Anticonvulsants; Carbamazepine; Clobazam; Clonazepam; Databases, Factual; Drug Therapy, Combination; Epilepsy; Gabapentin; Humans; Japan; Lacosamide; Lamotrigine; Levetiracetam; Lorazepam; Pharmacovigilance; Phenytoin; Stevens-Johnson Syndrome; Valproic Acid

2020
Autonomic functions in focal epilepsy: A comparison between lacosamide and carbamazepine monotherapy.
    Journal of the neurological sciences, 2020, 11-15, Volume: 418

    Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Hand Strength; Humans; Lacosamide

2020
Therapeutic Monitoring of Lacosamide in Japanese Patients With Epilepsy: Clinical Response, Tolerability, and Optimal Therapeutic Range.
    Therapeutic drug monitoring, 2020, Volume: 42, Issue:5

    Topics: Adult; Anticonvulsants; Asian People; Carbamazepine; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Lacosamide; Male; Phenobarbital; Phenytoin; Sodium Channel Blockers

2020
Factors correlated with intracranial interictal epileptiform discharges in refractory epilepsy.
    Epilepsia, 2021, Volume: 62, Issue:2

    Topics: Adult; Anticonvulsants; Attention; Carbamazepine; Drug Resistant Epilepsy; Electrocorticography; Female; Humans; Lacosamide; Lamotrigine; Levetiracetam; Male; Mental Recall; Middle Aged; Phenytoin; Time Factors; Topiramate; Zonisamide

2021
Impact of carbamazepine and lacosamide on serum lipid levels.
    Epilepsia, 2021, Volume: 62, Issue:4

    Topics: Anticonvulsants; Carbamazepine; Lacosamide; Lipids

2021
Epstein-Barr virus infection in a woman with aquaporin-4 seropositive neuromyelitis optica.
    Journal of neuroimmunology, 2021, 07-15, Volume: 356

    Topics: Adult; Aquaporin 4; Autoantibodies; Carbamazepine; Epstein-Barr Virus Infections; Female; Follow-Up Studies; Humans; Lacosamide; Neuromyelitis Optica

2021
Antiseizure Medication Concentrations During Pregnancy: Results From the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs (MONEAD) Study.
    JAMA neurology, 2022, 04-01, Volume: 79, Issue:4

    Topics: Adult; Anticonvulsants; Carbamazepine; Epilepsy; Female; Humans; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Pregnancy; Prospective Studies; Topiramate; Zonisamide

2022
Effect of Lacosamide therapy on blood cells and IgA levels in children and adolescents with epilepsy in a clinical setting.
    Epilepsy research, 2022, Volume: 187

    Topics: Acetamides; Adolescent; Anticonvulsants; Blood Cells; Carbamazepine; Child; Dose-Response Relationship, Drug; Epilepsy; Humans; Immunoglobulin A; Lacosamide; Lipids; Retrospective Studies; Treatment Outcome

2022
Structural mapping of Na
    Nature communications, 2023, 06-03, Volume: 14, Issue:1

    Topics: Analgesics; Carbamazepine; Humans; Lacosamide; Pain; Protein Domains; Voltage-Gated Sodium Channel Blockers; Voltage-Gated Sodium Channels

2023