Compounds > carbamazepine

carbamazepine and heme

carbamazepine has been researched along with heme in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19905 (62.50)18.7374
1990's1 (12.50)18.2507
2000's0 (0.00)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Badawy, AA; Morgan, CJ1
Brodie, MJ; Macphee, GJ; McGuire, GM; Moore, MR; Park, BK; Thompson, GG1
Atsmon, A; Epstein, O; Greenblat, Y; Schoenfeld, N1
Brodie, MJ; Goldberg, A; Macphee, GJ; Moore, MR; Philip, MF; Rapeport, WG; Thompson, GG; Yeung Laiwah, AA1
Brodie, MJ; Goldberg, A; Kehoe, B; McGuire, G; Meissner, PN; Moore, MR; Yeung Laiwah, AC1
Brodie, MJ; Connell, JC; Moore, MR; Rapeport, WG; Thompson, GG1
Hata, M; Honma, T; Hoshino, T; Yuki, H1
Bounds, PL; Caflisch, A; Davydov, DR; Halpert, JR; Knehans, T; Koppenol, WH; Müller, CS; von Mandach, U1

Other Studies

8 other study(ies) available for carbamazepine and heme

ArticleYear
Effects of acute carbamazepine administration on haem metabolism in rat liver.
    Biochemical pharmacology, 1992, Apr-01, Volume: 43, Issue:7

    Topics: 5-Aminolevulinate Synthetase; Allopurinol; Animals; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Indoleamine-Pyrrole 2,3,-Dioxygenase; Liver; Male; Porphyrias; Rats; Rats, Inbred Strains; Tryptophan Oxygenase

1992
The effects of chronic carbamazepine treatment of haem biosynthesis in man and rat.
    European journal of clinical pharmacology, 1988, Volume: 35, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Adolescent; Adult; Aged; Aminolevulinic Acid; Ammonia-Lyases; Animals; Carbamazepine; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Middle Aged; Porphobilinogen; Porphobilinogen Synthase; Porphyrins; Rats; Rats, Inbred Strains

1988
The influence of carbamazepine on the heme biosynthetic pathway.
    Biochemical medicine, 1985, Volume: 34, Issue:3

    Topics: 5-Aminolevulinate Synthetase; Allylisopropylacetamide; Animals; Carbamazepine; Cells, Cultured; Chick Embryo; Drug Synergism; Heme; Hydroxymethylbilane Synthase; Liver; Porphobilinogen Synthase; Porphyrins; Proteins; Time Factors; Uroporphyrinogen Decarboxylase

1985
Carbamazepine-induced non-hereditary acute porphyria.
    Lancet (London, England), 1983, Apr-09, Volume: 1, Issue:8328

    Topics: 5-Aminolevulinate Synthetase; Acute Disease; Adult; Carbamazepine; Diagnosis, Differential; Epilepsy; Erythrocytes; Female; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Porphyrias

1983
Carbamazepine and haem biosynthesis.
    Lancet (London, England), 1983, Oct-08, Volume: 2, Issue:8354

    Topics: Carbamazepine; Child; Heme; Humans; Porphobilinogen Synthase; Uroporphyrinogens

1983
Effect of carbamazepine on haem biosynthesis in man.
    European journal of clinical investigation, 1984, Volume: 14, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Adult; Carbamazepine; Erythrocytes; Heme; Humans; Hydroxymethylbilane Synthase; Leukocytes; Male; Porphyrins

1984
Prediction of sites of metabolism in a substrate molecule, instanced by carbamazepine oxidation by CYP3A4.
    Bioorganic & medicinal chemistry, 2012, Jan-15, Volume: 20, Issue:2

    Topics: Binding Sites; Carbamazepine; Cytochrome P-450 CYP3A; Heme; Iron; Molecular Dynamics Simulation; Oxidation-Reduction; Protein Structure, Tertiary; Substrate Specificity

2012
Concurrent cooperativity and substrate inhibition in the epoxidation of carbamazepine by cytochrome P450 3A4 active site mutants inspired by molecular dynamics simulations.
    Biochemistry, 2015, Jan-27, Volume: 54, Issue:3

    Topics: Carbamazepine; Catalytic Domain; Cytochrome P-450 CYP3A; Epoxy Compounds; Heme; Humans; Molecular Dynamics Simulation; Mutant Proteins; Mutation; Substrate Specificity

2015