carbamazepine and flunarizine

carbamazepine has been researched along with flunarizine in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.00)18.7374
1990's7 (35.00)18.2507
2000's6 (30.00)29.6817
2010's6 (30.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Anger, T; Madge, DJ; Mulla, M; Riddall, D1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Harker, LA; Murai, K; Stouffer, JL; Tyler, RS1
Czuczwar, SJ; Gasior, M; Kleinrok, Z1
Drake, ME; Mikati, M; Olson, L; Pellock, JM; Pledger, GW; Sackellares, JC; Sahlroot, JT; Treiman, DM; Tsay, JY; Wright, FS1
Pleuvry, BJ; Rodger, C1
Bialer, M1
Mahmood, I; Sahlroot, JT1
David, J; Joseph, S; Joseph, T1
Fricke, K; Henning, S; Henschke, U; Lang, N; Liebetanz, D; Nitsche, MA; Paulus, W; Schlitterlau, A; Tergau, F1
Kitano, H; Shinohara, H; Zakir Hossain, SM1
Kong, X; Li, N; Ma, F; Xin, Y; Zhao, Y1
Hoekstra, CE; Rovers, MM; Rynja, SP; van Zanten, GA1
Chauvette, S; Timofeev, I1
Aumann, D; Ayoub, A; Born, J; Hörschelmann, A; Kouchekmanesch, A; Marshall, L; Paul, P1

Reviews

4 review(s) available for carbamazepine and flunarizine

ArticleYear
Medicinal chemistry of neuronal voltage-gated sodium channel blockers.
    Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2

    Topics: Amyotrophic Lateral Sclerosis; Analgesics; Anticonvulsants; Epilepsy; Humans; Ion Channel Gating; Models, Molecular; Mutation; Nerve Tissue Proteins; Neuroprotective Agents; Protein Binding; Sodium Channel Blockers; Sodium Channels; Stroke

2001
Review of pharmacologic treatment of tinnitus.
    The American journal of otology, 1992, Volume: 13, Issue:5

    Topics: Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Double-Blind Method; Female; Flunarizine; Humans; Lidocaine; Male; Streptomycin; Tinnitus

1992
Comparative pharmacokinetics of the newer antiepileptic drugs.
    Clinical pharmacokinetics, 1993, Volume: 24, Issue:6

    Topics: Acetamides; Acetates; Amines; Aminocaproates; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Dioxolanes; Felbamate; Flunarizine; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Oxcarbazepine; Phenylcarbamates; Propylene Glycols; Tiagabine; Topiramate; Triazines; Vigabatrin

1993
Anticonvulsants for tinnitus.
    The Cochrane database of systematic reviews, 2011, Jul-06, Issue:7

    Topics: Administration, Oral; Amines; Anticonvulsants; Carbamazepine; Chronic Disease; Cyclohexanecarboxylic Acids; Flunarizine; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Randomized Controlled Trials as Topic; Tinnitus; Triazines

2011

Trials

5 trial(s) available for carbamazepine and flunarizine

ArticleYear
Flunarizine for treatment of partial seizures: results of a concentration-controlled trial.
    Neurology, 1994, Volume: 44, Issue:10

    Topics: Adolescent; Adult; Aged; Carbamazepine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Epilepsy; Female; Flunarizine; Half-Life; Humans; Male; Middle Aged; Phenytoin; Treatment Outcome

1994
A limited sampling method for the estimation of flunarizine area under the curve (AUC) and maximum plasma concentration (Cmax).
    Biopharmaceutics & drug disposition, 1997, Volume: 18, Issue:2

    Topics: Anticonvulsants; Area Under Curve; Carbamazepine; Drug Therapy, Combination; Flunarizine; Humans; Linear Models; Models, Biological; Models, Statistical; Phenytoin

1997
Pharmacological modulation of cortical excitability shifts induced by transcranial direct current stimulation in humans.
    The Journal of physiology, 2003, Nov-15, Volume: 553, Issue:Pt 1

    Topics: Adult; Calcium Channel Blockers; Carbamazepine; Cerebral Cortex; Dextromethorphan; Electric Stimulation; Electromyography; Evoked Potentials, Motor; Excitatory Amino Acid Antagonists; Female; Flunarizine; Humans; Male; Motor Cortex; Motor Neurons; Pyramidal Cells; Receptors, N-Methyl-D-Aspartate; Sex Characteristics; Sodium Channel Blockers

2003
[Efficacy of carbamazepine combined with flunarizine hydrochloride for treating tinnitus].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2008, Volume: 22, Issue:22

    Topics: Adolescent; Adult; Aged; Carbamazepine; Double-Blind Method; Drug Therapy, Combination; Flunarizine; Hearing Tests; Humans; Middle Aged; Prospective Studies; Tinnitus; Young Adult

2008
Differential effects on fast and slow spindle activity, and the sleep slow oscillation in humans with carbamazepine and flunarizine to antagonize voltage-dependent Na+ and Ca2+ channel activity.
    Sleep, 2013, Jun-01, Volume: 36, Issue:6

    Topics: Adult; Brain; Calcium Channel Blockers; Calcium Channels; Carbamazepine; Cross-Over Studies; Double-Blind Method; Electroencephalography; Female; Flunarizine; Humans; Male; Sleep Stages; Sodium Channel Blockers; Sodium Channels

2013

Other Studies

11 other study(ies) available for carbamazepine and flunarizine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Influence of BAY k-8644, a calcium channel agonist, on the anticonvulsant activity of conventional anti-epileptics against electroconvulsions in mice.
    Neuropharmacology, 1995, Volume: 34, Issue:4

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Carbamazepine; Drug Synergism; Drug Therapy, Combination; Electroshock; Flunarizine; Male; Mice; Phenobarbital; Valproic Acid

1995
Protective effect of flunarizine and nifedipine alone and in combination with anticonvulsant drugs against PTZ-induced seizures in mice.
    Neuropharmacology, 1993, Volume: 32, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Ethosuximide; Female; Flunarizine; Male; Mice; Nifedipine; Pentylenetetrazole; Phenytoin; Seizures

1993
Additive anticonvulsant effect of flunarizine and sodium valproate on electroshock and chemoshock induced seizures in mice.
    Indian journal of physiology and pharmacology, 1998, Volume: 42, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Drug Synergism; Drug Therapy, Combination; Electroshock; Ethosuximide; Flunarizine; Male; Mice; Motor Activity; Pentylenetetrazole; Phenytoin; Seizures; Valproic Acid

1998
Drug assessment based on detection of L-glutamate released from C6 glioma cells using an enzyme-luminescence method.
    Analytical chemistry, 2008, May-15, Volume: 80, Issue:10

    Topics: 4-Aminopyridine; Animals; Brain Neoplasms; Carbamazepine; Cell Line, Tumor; Enzymes; Flunarizine; Glioma; Glutamic Acid; Lidocaine; Luminescence; Nickel; Nifedipine; Rats; Veratridine

2008
The spindles: are they still thalamic?
    Sleep, 2013, Jun-01, Volume: 36, Issue:6

    Topics: Calcium Channel Blockers; Calcium Channels; Carbamazepine; Female; Flunarizine; Humans; Male; Sleep Stages; Sodium Channel Blockers; Sodium Channels

2013