carbamazepine and cyclosporine

carbamazepine has been researched along with cyclosporine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (6.06)18.2507
2000's9 (27.27)29.6817
2010's20 (60.61)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Chang, TK; Ensom, MH; Kiang, TK1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL1
Baltes, S; Fedrowitz, M; Gastens, AM; Kaever, V; Löscher, W; Potschka, H1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Erdmann, F; Fischer, G; Harris, R; Hopkins, S; Huang, Z; Murray, MG; Ribeill, Y; Scorneaux, B; Smitley, C; Wring, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y1
Bae, MA; Choi, J; Choi, JH; Kim, MJ; Kim, YC; Lee, D; Lee, KR; Lee, S; Park, CJ; Seo, J; Shin, DS; Song, YK1
Bigler, S; Hänseler, E; Wad, N1
Havill, J; Jarrett, P; Pullon, H; Rademaker, M1
Liu, XD; Sun, JJ; Xie, L1
Liu, HY; Liu, X; Liu, XD; Liu, YC; Wang, GJ; Xie, L; Yang, HW; Zhang, DM1
Jiang, XH; Jin, JX; Ju, Y; Liu, CX; Qiu, W1
Broadfoot, AJ; Fernando, SL1
Beligere, GS; Chen, YY; Fishpaugh, JR; Grote, J; Harwick, LC; Lin, Z; Nair, RK; Rege, SD; Rupprecht, KR1
Chebrot, M; Douroumis, D; Lafarga, AA; Lamprou, DA; Patil, A; Urquhart, A1
Ahad, A; Al-Jenoobi, FI; Al-Mohizea, AM; Al-Suwayeh, SA; Alam, MA; Alkharfy, KM; Iqbal, M; Korashy, HM; Raish, M1
Dutz, JP; Kirchhof, MG; Wong, A1
Nakamura, R; Saito, Y1
Al Abri, AM; Al Rajaibi, R; Al Rumhi, T1

Reviews

4 review(s) available for carbamazepine and cyclosporine

ArticleYear
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Mechanisms of Severe Cutaneous Adverse Reactions and a New Treatment Strategy].
    Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:12

    Topics: Acetaminophen; Adrenal Cortex Hormones; Allopurinol; Antigens, Differentiation, T-Lymphocyte; Carbamazepine; CD8-Positive T-Lymphocytes; Cyclosporine; Epidermis; Etanercept; Fas Ligand Protein; HLA Antigens; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Japan; Lamotrigine; Plasma Exchange; Stevens-Johnson Syndrome; Tumor Necrosis Factor-alpha

2019
Carbamazepine-Induced Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis Overlap Treated Successfully with Oral Cyclosporin: Case report and literature review.
    Sultan Qaboos University medical journal, 2021, Volume: 21, Issue:3

    Topics: Adult; Carbamazepine; Cyclosporine; Female; Humans; Oman; Stevens-Johnson Syndrome

2021

Trials

1 trial(s) available for carbamazepine and cyclosporine

ArticleYear
Analyses of the pattern of therapeutic drug monitoring in a university hospital laboratory. Suitability and performance of the CEDIA assays.
    Wiener klinische Wochenschrift. Supplementum, 1992, Volume: 191

    Topics: Carbamazepine; Chromatography, High Pressure Liquid; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy; Humans; Immunoenzyme Techniques; Pharmacokinetics; Phenobarbital; Phenytoin; Quality Control; Theophylline

1992

Other Studies

28 other study(ies) available for carbamazepine and cyclosporine

ArticleYear
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
    Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18

    Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride

2005
Differences in the transport of the antiepileptic drugs phenytoin, levetiracetam and carbamazepine by human and mouse P-glycoprotein.
    Neuropharmacology, 2007, Volume: 52, Issue:2

    Topics: Analysis of Variance; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Carbamazepine; Cell Line; Cyclosporine; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Gene Expression; Humans; Levetiracetam; Mice; Phenytoin; Piracetam; Transfection

2007
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
SCY-635, a novel nonimmunosuppressive analog of cyclosporine that exhibits potent inhibition of hepatitis C virus RNA replication in vitro.
    Antimicrobial agents and chemotherapy, 2010, Volume: 54, Issue:2

    Topics: Animals; Antiviral Agents; Cell Line; Cells, Cultured; Cyclophilin A; Cyclosporins; Dogs; Dose-Response Relationship, Drug; Enzyme Activation; Haplorhini; Hepacivirus; Hepatitis C; Hepatocytes; Humans; Immunosuppressive Agents; Interleukin-2; Jurkat Cells; Leukocytes, Mononuclear; Mice; Molecular Structure; Rats; RNA, Viral; Virus Replication

2010
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships.
    Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16

    Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone

2016
Interplay among Conformation, Intramolecular Hydrogen Bonds, and Chameleonicity in the Membrane Permeability and Cyclophilin A Binding of Macrocyclic Peptide Cyclosporin O Derivatives.
    Journal of medicinal chemistry, 2021, 06-24, Volume: 64, Issue:12

    Topics: Animals; Caco-2 Cells; Cell Membrane Permeability; Cyclization; Cyclophilin A; Cyclosporine; Cyclosporins; Drug Design; Humans; Hydrogen Bonding; Male; Mice, Inbred ICR; Molecular Conformation; Protein Binding

2021
Toxic epidermal necrolysis treated with cyclosporin and granulocyte colony stimulating factor.
    Clinical and experimental dermatology, 1997, Volume: 22, Issue:3

    Topics: Adult; Analgesics, Non-Narcotic; Carbamazepine; Cyclosporine; Female; Filgrastim; Granulocyte Colony-Stimulating Factor; Humans; Immunosuppressive Agents; Neutropenia; Recombinant Proteins; Stevens-Johnson Syndrome

1997
Transport of carbamazepine and drug interactions at blood-brain barrier.
    Acta pharmacologica Sinica, 2006, Volume: 27, Issue:2

    Topics: Animals; Anticonvulsants; Benzodiazepines; Blood-Brain Barrier; Carbamazepine; Cells, Cultured; Cerebral Cortex; Cyclosporine; Dinitrophenols; Dose-Response Relationship, Drug; Endothelial Cells; Microcirculation; Olanzapine; Rats; Rats, Sprague-Dawley; Time Factors

2006
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro.
    Neuroscience letters, 2008, Apr-04, Volume: 434, Issue:3

    Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Cells, Cultured; Cerebral Arteries; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Immunosuppressive Agents; Indicators and Reagents; Microcirculation; Phenobarbital; Phenytoin; Rats; Rhodamine 123; Sodium Channel Blockers; Time; Up-Regulation; Valproic Acid; Verapamil

2008
Effect of berberine on the pharmacokinetics of substrates of CYP3A and P-gp.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:11

    Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Berberine; Biological Availability; Carbamazepine; Cyclosporine; Cytochrome P-450 CYP3A; Digoxin; Drug Interactions; Male; Rats; Rats, Wistar

2009
Prevention of severe cutaneous adverse drug reactions: the emerging value of pharmacogenetic screening.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2010, Mar-23, Volume: 182, Issue:5

    Topics: Adult; Alleles; Allopurinol; Anticonvulsants; Asian People; Carbamazepine; China; Cyclosporine; Drug Hypersensitivity; Genetic Predisposition to Disease; Genetic Testing; Gout Suppressants; HLA-B Antigens; Humans; Immunization, Passive; Immunosuppressive Agents; Keratoconjunctivitis; Male; Stevens-Johnson Syndrome; Urethritis

2010
Development of a dot-blot assay for screening monoclonal antibodies to low-molecular-mass drugs.
    Analytical biochemistry, 2010, Dec-15, Volume: 407, Issue:2

    Topics: Acridines; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antibodies, Monoclonal; Anticonvulsants; Carbamazepine; Collodion; Cyclosporine; Gentamicins; Hydrocortisone; Immunoblotting; Immunosuppressive Agents; Methotrexate; Pharmaceutical Preparations; Reproducibility of Results; Sirolimus; Tacrolimus

2010
Inclusion of water insoluble drugs in amorphous silica nanoparticles.
    Journal of biomedical nanotechnology, 2012, Volume: 8, Issue:4

    Topics: Adsorption; Caco-2 Cells; Calorimetry, Differential Scanning; Carbamazepine; Cell Line; Cell Survival; Cyclosporine; Drug Carriers; Drug Compounding; Humans; Ibuprofen; Nanoparticles; Pharmaceutical Preparations; Powders; Silicon Dioxide; Solubility; Surface Properties; Water; X-Ray Diffraction

2012
Pharmacokinetic interaction studies of fenugreek with CYP3A substrates cyclosporine and carbamazepine.
    European journal of drug metabolism and pharmacokinetics, 2014, Volume: 39, Issue:2

    Topics: Animals; Carbamazepine; Cyclosporine; Cytochrome P-450 CYP3A; Female; Herb-Drug Interactions; Male; Rabbits; Substrate Specificity; Trigonella

2014
Cyclosporine Treatment of Drug-Induced Hypersensitivity Syndrome.
    JAMA dermatology, 2016, 11-01, Volume: 152, Issue:11

    Topics: Adult; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Cyclosporine; Dermatologic Agents; Drug Hypersensitivity Syndrome; Female; Hospitals, University; Humans; Minocycline; Retrospective Studies; Risk Factors; Treatment Outcome

2016