carbamazepine and clozapine

carbamazepine has been researched along with clozapine in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (5.71)	18.7374
1990's	14 (20.00)	18.2507
2000's	23 (32.86)	29.6817
2010's	26 (37.14)	24.3611
2020's	3 (4.29)	2.80

Authors

Authors	Studies
Hino, K; Karasawa, T; Masuda, Y; Nagai, Y; Oka, M; Uno, H	1
Andrews, PR; Craik, DJ; Martin, JL	1
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Faller, B; Wohnsland, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Bergström, F; Giordanetto, F; Rehngren, M; Tunek, A; Wan, H	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Ahman, M; Holmén, AG; Wan, H	1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Boriss, H; Braggio, S; Corbioli, S; Fontana, S; Helmdach, L; Longhi, R; Schiller, J; Vinco, F	1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ	1
Sen, S; Sinha, N	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Filipek, B; Gunia-Krzyżak, A; Marona, H; Nitek, W; Pańczyk, K; Pękala, E; Rapacz, A; Słoczyńska, K; Waszkielewicz, AM; Żelaszczyk, D; Żesławska, E	1
Koponen, HJ; Liukkonen, J; Nousiainen, U	1
Friedenberg, WR; Gerson, SL; Lee, D; Lieberman, JA; Marx, JJ; Meltzer, H	1
Christison, GW; Kirch, DG; Wyatt, RJ	1
Diedrich, U; Müller, P	1
Becker, T; Fritze, J; Müller, T	1
Campbell, M; Cueva, JE	1
Bak, TH; Bauer, M; Hellweg, R; Reischies, FM; Schaub, RT	1
Hakola, P; Tiihonen, J; Vartiainen, H	1
Calabrese, JR; Woyshville, MJ	1
Vanelle, JM	1
Bertilsson, L; Bondesson, U; Jerling, M; Lindström, L	1
Albers, M; Junghan, U; Woggon, B	1
Huttunen, MO; Lehtovaara, R; Raitasuo, V	1
Brawman-Mintzer, O; Mintzer, JE	1
Keck, PE; McElroy, SL; Strakowski, SM	1
Rittmannsberger, H	1
Alexander, B; Langbehn, DR	1
Nemeroff, CB	1
Jiang, A; LoGrasso, PV; Stearns, BA; Trauger, JW	1
Freeman, MP; Gelenberg, AJ; Gnanadesikan, M	1
Antonetti, DA; Maines, LW; Smith, CD; Wolpert, EB	1
Green, AC; Harrison, PK; Sheridan, RD; Tattersall, JE	1
Danielyan, A; Kowatch, RA	1
Belova, MV; Lisovik, ZA; Livanov, AS; Luzhnikov, EA; Ostapenko, YN	1
Humphreys, WG; Ma, L; Zhang, H; Zhu, M	1
Saleh, C	1
Abílio, VC; Calzavara, MB; Levin, R; Medrano, WA; Niigaki, ST; Santos, CM	1
Chen, Y; Groothuis, GM; Hadi, M; Merema, MT; Starokozhko, V	1
Askenazy, F; Drici, M; Lavrut, T; Menard, ML; Yagoubi, F	1
Chen, CC; Chen, WJ; Kuo, CJ; Liao, YT; Liu, HC; Yang, SY	1
Cummings, MA; Meyer, JM; Proctor, G; Stahl, SM	1
Davern, P; Hodnett, BK; Hudson, S; Kumar, A	1
Corsini, E; Galbiati, V; Iulini, M; Maddalon, A; Marinovich, M	1
de Leon, J	1

Reviews

12 review(s) available for carbamazepine and clozapine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
When symptoms persist: choosing among alternative somatic treatments for schizophrenia. Schizophrenia bulletin, 1991, Volume: 17, Issue:2 Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clozapine; Double-Blind Method; Electroconvulsive Therapy; Humans; Levodopa; Lithium; Propranolol; Reserpine; Schizophrenia	1991
Psychopharmacology in child and adolescent psychiatry: a review of the past seven years. Part II. Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:10 Topics: Adolescent; Alprazolam; Anticonvulsants; Antipsychotic Agents; Anxiety, Separation; Bipolar Disorder; Carbamazepine; Child; Child Behavior Disorders; Child, Preschool; Clonidine; Clozapine; Depressive Disorder; Dose-Response Relationship, Drug; Feeding and Eating Disorders; Fluoxetine; Humans; Imipramine; Lithium; Mutism; Obsessive-Compulsive Disorder; Phenobarbital; Phenytoin; Phobic Disorders; Schizophrenia; Sleep Wake Disorders; Tranquilizing Agents	1995
A medication algorithm for treatment of bipolar rapid cycling? The Journal of clinical psychiatry, 1995, Volume: 56 Suppl 3 Topics: Algorithms; Bipolar Disorder; Carbamazepine; Clozapine; Controlled Clinical Trials as Topic; Drug Administration Schedule; Drug Therapy, Combination; Electroconvulsive Therapy; Humans; Lithium; Treatment Outcome; Valproic Acid	1995
[Resistant schizophrenia: what chemotherapy?]. Annales medico-psychologiques, 1993, Volume: 151, Issue:4 Topics: Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clozapine; Drug Therapy, Combination; Humans; Lithium; Propranolol; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology	1993
Agitation as a possible expression of generalized anxiety disorder in demented elderly patients: toward a treatment approach. The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 7 Topics: Aged; Aggression; Antipsychotic Agents; Anxiety Disorders; Behavior Therapy; Buspirone; Carbamazepine; Clozapine; Combined Modality Therapy; Decision Trees; Dementia; Humans; Ondansetron; Psychomotor Agitation; Serotonin; Trazodone	1996
New developments in the pharmacologic treatment of schizoaffective disorder. The Journal of clinical psychiatry, 1996, Volume: 57 Suppl 9 Topics: Antidepressive Agents; Antipsychotic Agents; Carbamazepine; Clinical Trials as Topic; Clozapine; Drug Therapy, Combination; Humans; Psychotic Disorders; Receptors, Serotonin; Risperidone; Serotonin Antagonists; Treatment Outcome; Valproic Acid	1996
An ever-increasing pharmacopoeia for the management of patients with bipolar disorder. The Journal of clinical psychiatry, 2000, Volume: 61 Supp 13 Topics: Acetates; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroconvulsive Therapy; Electromagnetic Phenomena; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Lithium; Olanzapine; Pirenzepine; Risperidone; Topiramate; Treatment Outcome; Triazines; Valproic Acid	2000
Alternatives to lithium and divalproex in the maintenance treatment of bipolar disorder. Bipolar disorders, 2003, Volume: 5, Issue:3 Topics: Acetates; Amines; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clozapine; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Donepezil; Fatty Acids, Omega-3; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Indans; Lamotrigine; Lithium Carbonate; Olanzapine; Piperazines; Piperidines; Pirenzepine; Quetiapine Fumarate; Risperidone; Thiazoles; Topiramate; Treatment Outcome; Triazines; Valproic Acid	2003
Management options for bipolar disorder in children and adolescents. Paediatric drugs, 2005, Volume: 7, Issue:5 Topics: Adolescent; Benzodiazepines; Bipolar Disorder; Carbamazepine; Child; Clozapine; Dibenzothiazepines; Humans; Lithium; Olanzapine; Quetiapine Fumarate; Risperidone; Valproic Acid	2005
Psychopharmacology of Persistent Violence and Aggression. The Psychiatric clinics of North America, 2016, Volume: 39, Issue:4 Topics: Aggression; Antimanic Agents; Antipsychotic Agents; Brain Injuries, Traumatic; Carbamazepine; Clozapine; Dementia; Humans; Impulsive Behavior; Neurobiology; Psychopharmacology; Psychotic Disorders; Schizophrenia; Violence	2016

Trials

1 trial(s) available for carbamazepine and clozapine

Article	Year
When symptoms persist: choosing among alternative somatic treatments for schizophrenia. Schizophrenia bulletin, 1991, Volume: 17, Issue:2 Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clozapine; Double-Blind Method; Electroconvulsive Therapy; Humans; Levodopa; Lithium; Propranolol; Reserpine; Schizophrenia	1991

Other Studies

58 other study(ies) available for carbamazepine and clozapine

Article	Year
A novel class of potential central nervous system agents. 3-Phenyl-2-(1-piperazinyl)-5H-1-benzazepines. Journal of medicinal chemistry, 1988, Volume: 31, Issue:1 Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benzazepines; Body Temperature Regulation; Brain; Electroshock; Exploratory Behavior; Homovanillic Acid; Hypothermia; Indicators and Reagents; Male; Mice; Mice, Inbred Strains; Piperazines; Rats; Rats, Inbred Strains; Reserpine; Seizures; Structure-Activity Relationship	1988
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
High-throughput permeability pH profile and high-throughput alkane/water log P with artificial membranes. Journal of medicinal chemistry, 2001, Mar-15, Volume: 44, Issue:6 Topics: Alkanes; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Membranes, Artificial; Octanols; Permeability; Pharmaceutical Preparations; Solubility; Water	2001
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. Bioorganic & medicinal chemistry letters, 2005, Sep-15, Volume: 15, Issue:18 Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride	2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
High-throughput screening of drug-brain tissue binding and in silico prediction for assessment of central nervous system drug delivery. Journal of medicinal chemistry, 2007, Sep-20, Volume: 50, Issue:19 Topics: Animals; Brain; Central Nervous System Agents; Dialysis; Hydrophobic and Hydrophilic Interactions; In Vitro Techniques; Mice; Models, Statistical; Protein Binding; Quantitative Structure-Activity Relationship; Rats	2007
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model. Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2 Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs. Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6 Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry	2009
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data. European journal of medicinal chemistry, 2009, Volume: 44, Issue:11 Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:2 Topics: Absorption; Albumins; Animals; Brain; Brain Chemistry; Cell Membrane; Chromatography, High Pressure Liquid; Drug Evaluation, Preclinical; In Vitro Techniques; Lipids; Male; Microdialysis; Pharmaceutical Preparations; Protein Binding; Rats; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Swine; Tissue Distribution	2011
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3 Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results	2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model. European journal of medicinal chemistry, 2011, Volume: 46, Issue:2 Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship	2011
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors. Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1 Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity	2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Structure-anticonvulsant activity studies in the group of (E)-N-cinnamoyl aminoalkanols derivatives monosubstituted in phenyl ring with 4-Cl, 4-CH Bioorganic & medicinal chemistry, 2017, 01-15, Volume: 25, Issue:2 Topics: Amino Alcohols; Animals; Anticonvulsants; Crystallography, X-Ray; Disease Models, Animal; Dose-Response Relationship, Drug; Electroshock; Mice; Models, Molecular; Molecular Structure; Rats; Seizures; Structure-Activity Relationship	2017
Clinical picture and long-term course of epileptic seizures that occur during clozapine treatment. Psychiatry research, 1992, Volume: 44, Issue:2 Topics: Adult; Carbamazepine; Clonazepam; Clozapine; Electroencephalography; Epilepsies, Myoclonic; Epilepsy, Tonic-Clonic; Female; Follow-Up Studies; Humans; Male; Retrospective Studies; Schizophrenia; Schizophrenic Psychology	1992
Polypharmacy in fatal clozapine-associated agranulocytosis. Lancet (London, England), 1991, Jul-27, Volume: 338, Issue:8761 Topics: Agranulocytosis; Carbamazepine; Clozapine; Humans; Male; Middle Aged; Monitoring, Physiologic; Schizophrenia	1991
[Severe late dyskinesia caused by neuroleptics in a young female. Follow-up and treatment]. Der Nervenarzt, 1989, Volume: 60, Issue:12 Topics: Adolescent; Carbamazepine; Clozapine; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Follow-Up Studies; Haloperidol; Humans; Meclofenoxate; Neuroleptic Malignant Syndrome; Schizophrenia; Schizophrenic Psychology; Tiapamil Hydrochloride	1989
[Neuroleptic malignant syndrome]. Deutsche medizinische Wochenschrift (1946), 1989, Mar-17, Volume: 114, Issue:11 Topics: Aged; Carbamazepine; Clozapine; Drug Therapy, Combination; Humans; Lithium; Male; Neuroleptic Malignant Syndrome	1989
Myoclonus in patients treated with clozapine: a case series. The Journal of clinical psychiatry, 1995, Volume: 56, Issue:9 Topics: Adult; Antipsychotic Agents; Carbamazepine; Clozapine; Depressive Disorder; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Dyskinesia, Drug-Induced; Female; Hospitalization; Humans; Male; Middle Aged; Myoclonus; Schizophrenia	1995
Carbamazepine-induced changes in plasma levels of neuroleptics. Pharmacopsychiatry, 1995, Volume: 28, Issue:1 Topics: Adult; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Clozapine; Female; Humans; Male; Middle Aged; Oxcarbazepine; Thioridazine	1995
Fluvoxamine inhibition and carbamazepine induction of the metabolism of clozapine: evidence from a therapeutic drug monitoring service. Therapeutic drug monitoring, 1994, Volume: 16, Issue:4 Topics: Adult; Aged; Carbamazepine; Clozapine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Drug Monitoring; Female; Fluvoxamine; Humans; Male; Middle Aged; Mixed Function Oxygenases; Oxidoreductases	1994
Increased risk of hematological side-effects in psychiatric patients treated with clozapine and carbamazepine? Pharmacopsychiatry, 1993, Volume: 26, Issue:6 Topics: Agranulocytosis; Carbamazepine; Clozapine; Drug Interactions; Hematologic Diseases; Humans; Mental Disorders; Risk	1993
Carbamazepine and plasma levels of clozapine. The American journal of psychiatry, 1993, Volume: 150, Issue:1 Topics: Adult; Carbamazepine; Clozapine; Drug Interactions; Drug Therapy, Combination; Epilepsy; Humans; Male; Microsomes, Liver; Schizophrenia	1993
Asterixis induced by psychotropic drug treatment. Clinical neuropharmacology, 1996, Volume: 19, Issue:4 Topics: Adult; Aged; Carbamazepine; Clozapine; Female; Humans; Male; Middle Aged; Mood Disorders; Psychotropic Drugs; Tremor	1996
Increased risk of side-effects in psychiatric patients treated with clozapine and carbamazepine: a reanalysis. Pharmacopsychiatry, 2000, Volume: 33, Issue:5 Topics: Agranulocytosis; Anticonvulsants; Antipsychotic Agents; Carbamazepine; Clozapine; Drug Interactions; Humans; Risk	2000
Kinetics of allopregnanolone formation catalyzed by human 3 alpha-hydroxysteroid dehydrogenase type III (AKR1C2). Biochemistry, 2002, Nov-12, Volume: 41, Issue:45 Topics: 3-alpha-Hydroxysteroid Dehydrogenase (B-Specific); 3-Hydroxysteroid Dehydrogenases; 5-alpha-Dihydroprogesterone; Carbamazepine; Catalysis; Clozapine; Enzyme Activation; Enzyme Inhibitors; Fluoxetine; Flurbiprofen; Humans; Hydroxysteroid Dehydrogenases; Kinetics; Oxidation-Reduction; Pregnanediones; Pregnanolone; Recombinant Fusion Proteins; Selective Serotonin Reuptake Inhibitors; Substrate Specificity; Ursodeoxycholic Acid	2002
Evaluation of the role of P-glycoprotein in the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells. Neuropharmacology, 2005, Volume: 49, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Anticonvulsants; Antipsychotic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Carbamazepine; Cattle; Cell Separation; Cells, Cultured; Cerebral Cortex; Clozapine; Endothelial Cells; Hydrocortisone; Paroxetine; Phenytoin; Rats; Retina; Selective Serotonin Reuptake Inhibitors	2005
Effects of anticonvulsants on soman-induced epileptiform activity in the guinea-pig in vitro hippocampus. European journal of pharmacology, 2005, Aug-22, Volume: 518, Issue:2-3 Topics: Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Chlormethiazole; Clozapine; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; In Vitro Techniques; Levetiracetam; Male; Phenylcarbamates; Phenylenediamines; Piracetam; Propylene Glycols; Soman; Topiramate	2005
Comparative assessment of blood and urine analyses in patients with acute poisonings by medical, narcotic substances and alcohol in clinical toxicology. Przeglad lekarski, 2005, Volume: 62, Issue:6 Topics: Acute Disease; Amitriptyline; Carbamazepine; Central Nervous System Agents; Clozapine; Ethanol; Female; Humans; Immunoenzyme Techniques; Male; Mass Spectrometry; Narcotics; Poisoning; Reproducibility of Results; Russia; Severity of Illness Index; Substance Abuse Detection; Substance-Related Disorders; Toxicology	2005
Detection and structural characterization of glutathione-trapped reactive metabolites using liquid chromatography-high-resolution mass spectrometry and mass defect filtering. Analytical chemistry, 2007, Nov-01, Volume: 79, Issue:21 Topics: Acetaminophen; Animals; Bile; Carbamazepine; Chromatography, Liquid; Clozapine; Cresols; Diclofenac; Glutathione; Humans; Microsomes, Liver; Molecular Structure; Oxidation-Reduction; Phenols; Rats; Reproducibility of Results; Sensitivity and Specificity; Skatole; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Time Factors	2007
How to treat DBS-induced mania? Journal of the neurological sciences, 2011, Feb-15, Volume: 301, Issue:1-2 Topics: Aged; Bipolar Disorder; Carbamazepine; Clozapine; Deep Brain Stimulation; Female; Humans; Male; Middle Aged; Parkinson Disease	2011
Spontaneously Hypertensive Rats (SHR) present deficits in prepulse inhibition of startle specifically reverted by clozapine. Progress in neuro-psychopharmacology & biological psychiatry, 2011, Aug-15, Volume: 35, Issue:7 Topics: Acoustic Stimulation; Amphetamine; Animals; Antimanic Agents; Antipsychotic Agents; Carbamazepine; Clozapine; Disease Models, Animal; Dopamine Antagonists; Dopamine Uptake Inhibitors; Male; Metoclopramide; Rats; Rats, Inbred SHR; Rats, Wistar; Reflex, Startle; Schizophrenia; Sensory Gating	2011
Mouse precision-cut liver slices as an ex vivo model to study idiosyncratic drug-induced liver injury. Chemical research in toxicology, 2012, Sep-17, Volume: 25, Issue:9 Topics: Animals; Benzodiazepines; Biomarkers; Carbamazepine; Cell Survival; Chemical and Drug Induced Liver Injury; Chemokines; Chromans; Clozapine; Cytokines; Diclofenac; Drug Synergism; Female; Glutathione; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; In Vitro Techniques; Ketoconazole; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Nitrogen Oxides; Olanzapine; Pyrimidines; Thiazolidinediones; Triazoles; Troglitazone; Voriconazole	2012
[Follow-up of a 16-year-old adolescent with early-onset schizophrenia and catatonic symptoms]. L'Encephale, 2013, Volume: 39 Suppl 1 Topics: Adolescent; Benzodiazepines; Carbamazepine; Clonazepam; Clozapine; Creatine Kinase; Diagnosis, Differential; Drug Resistance; Drug Substitution; Drug Therapy, Combination; Humans; Lorazepam; Male; Olanzapine; Patient Admission; Psychiatric Status Rating Scales; Psychometrics; Recurrence; Risperidone; Schizophrenia, Catatonic	2013
Antipsychotic drugs, mood stabilizers, and risk of pneumonia in bipolar disorder: a nationwide case-control study. The Journal of clinical psychiatry, 2013, Volume: 74, Issue:1 Topics: Adolescent; Adult; Anticonvulsants; Antimanic Agents; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Case-Control Studies; Clozapine; Cohort Studies; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Evidence-Based Medicine; Female; Hospitalization; Humans; Lithium Carbonate; Male; Middle Aged; Multivariate Analysis; Olanzapine; Pneumonia; Propensity Score; Risk Factors; Taiwan; Valproic Acid; Young Adult	2013
Modification of the zeta potential of montmorillonite to achieve high active pharmaceutical ingredient nanoparticle loading and stabilization with optimum dissolution properties. Colloids and surfaces. B, Biointerfaces, 2020, Volume: 193 Topics: Bentonite; Carbamazepine; Clozapine; Curcumin; Drug Compounding; Molecular Structure; Nanoparticles; Particle Size; Polymers; Solubility	2020
In vitro identification of drugs inducing systemic hypersensitivity reactions known in vivo to be associated with specific HLA genotypes. Toxicology in vitro : an international journal published in association with BIBRA, 2020, Volume: 68 Topics: B7-2 Antigen; Carbamazepine; Cell Survival; Clozapine; Dideoxynucleosides; Drug Hypersensitivity; Genotype; HLA Antigens; Humans; Intercellular Adhesion Molecule-1; Interleukin-8; Metformin; THP-1 Cells	2020
Precision psychiatry: The complexity of personalizing antipsychotic dosing. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2022, Volume: 58 Topics: Antipsychotic Agents; Benzodiazepines; Carbamazepine; Clozapine; Female; Humans; Male; Paliperidone Palmitate; Psychiatry; Risperidone	2022