carbamazepine and allopurinol

carbamazepine has been researched along with allopurinol in 74 studies

Research

Studies (74)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.70)	18.7374
1990's	2 (2.70)	18.2507
2000's	13 (17.57)	29.6817
2010's	52 (70.27)	24.3611
2020's	5 (6.76)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Topliss, JG; Yoshida, F	1
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL	1
Badawy, AA; Morgan, CJ	1
Alexopoulos, E; Chrisomalis, F; Karpouzas, J; Koukoudis, P; Papadimitriou, M; Papadopoulou, D; Sakellariou, G; Skenteris, N; Tsakaris, D	1
Raasch, RH	1
Chang, NC; Chen, YH; Dai, YS; Lin, MS; Pwu, RF	1
Chen, YT; Chung, WH; Hung, SI	1
Hashimoto, K; Tohyama, M	1
Chang, YC; Chiou, CC; Chung, WH; Ho, HC; Hong, HS; Hu, S; Hung, SI; Kuo, TT; Yang, LC	1
Asano, Y; Hirahara, K; Kano, Y; Shiohara, T	1
Jin, DK; Kim, SJ; Paik, KH; Park, SW; Sohn, YB	1
Broadfoot, AJ; Fernando, SL	1
Aouam, K; Ben Fredj, N; Ben Rhomdhane, F; Boughattas, N; Chaabane, A; Chakroun, M; Toumi, A	1
Chung, WH; Hung, SI	1
Arhan, E; Kurt, N; Kutsal, E; Ozcelik, A; Ozturk, B; Ozturk, HS; Serdaroglu, A; Sevinc, N	1
Kaniwa, N	1
Aihara, M	1
Cacoub, P; Descamps, V; Finzi, L; Meyer, O; Musette, P; Roujeau, JC; Speirs, C	1
Bharadwaj, M; Illing, P; McCluskey, J; Purcell, AW; Rossjohn, J; Theodossis, A	1
Eckels, D; Profaizer, T	1
Barbaud, A; Bollaert, M; Gastin, I; Jeulin, H; Rabaud, C; Schmutz, JL; Tréchot, P; Waton, J	1
Pirmohamed, M	1
Adam, J; Pichler, WJ; Yerly, D; Yun, J	1
Daghfous, R; El Fekih, N; Fazaa, B; Khaled, A; Souissi, A; Zeglaoui, F	1
Kaniwa, N; Saito, Y	1
Chao, L; Mei, H; Pan, XC; Tan, W; Wang, Q; Zhang, YL	1
Karlin, E; Phillips, E	1
Borroni, RG	1
Chen, CH; Chen, WL; Cheng, CY; Chung, WH; Deng, ST; Su, SC	1
Chen, X; Xiong, Y; Zhang, W	1
Chaikledkaew, U; Chantratita, W; Lee, MT; Mahasirimongkol, S; Patrinos, GP; Pavlidis, C; Suwankesawong, W; Zhang, Y	1
Bastuji-Garin, S; Chosidow, O; de Feraudy, S; Delfau-Larue, MH; Duong, TA; Ortonne, N; Roujeau, JC; Valeyrie-Allanore, L; Wechsler, J; Wolkenstein, P	1
Chen, SA; Fu, X; Luo, X; Ma, L; Meng, C; Sun, X; Xing, Q; Xu, J; Yan, S; Yang, F; Yang, Y; Zhu, Q	1
Chung, WH; Hung, SI; Mallal, S; Phillips, EJ; White, KD	1
Kim, DH; Kim, J; Kim, YJ; Lee, JH; Park, HJ; Park, JW; Park, KH	1
Kinoshita, Y; Saeki, H	1
Chung, WH; Dao, RL; Fan, WL; Hung, SI; Su, SC	1
Becquemont, L; Negrini, S	1
Adler, NR; Aung, AK; Ergen, EN; Goh, MSY; Phillips, EJ; Trubiano, J	1
Fricke-Galindo, I; LLerena, A; López-López, M	1
Li, M; Wang, F; Zhang, X; Zhao, YK; Zhu, Z	1
Aw, D; Chan, CL; Chong, YY; Dong, D; Koay, ES; Lateef, A; Lee, EJ; Lee, HY; Lee, SX; Lim, YL; Limenta, M; Loke, C; Lui, NL; Pang, SM; Ren, EC; Sung, C; Tan, L; Tan-Koi, WC; Tay, YK; Toh, D; Vasudevan, A	1
Illing, PT; McCluskey, J; Purcell, AW	1
Ha, JW; Hahm, JE; Kim, CW; Kim, SS; Lee, JY; Lee, SY	1
Chen, S; Gao, X; Luo, X; Wu, X; Xing, Q; Xiong, H; Yang, F; Zhu, Q	1
Dimas, K; Gerogianni, K; Tsezou, A	1
Cheng, CY; Cheng, FJ; Chuang, PC; Huang, YS; Pan, HY; Syu, FK	1
Chen, S; Jiang, M; Luo, X; Qin, S; Tang, C; Wang, L; Xing, Q; Xiong, H; Yang, F; Zhu, H; Zhu, Q	1
Kang, DY; Kang, HR; Kang, MG; Lee, JY; Park, HK; Sohn, KH; Yang, MS	1
Chan, FL; Dodiuk-Gad, RP; Hashimoto, R; Maharaj, A; Olteanu, C; Shear, NH; Ziv, M	1
Nakamura, R; Saito, Y	1
Krebs, K; Lauschke, VM; Milani, L; Zhou, Y	1
Choi, JH; Hur, GY; Jee, YK; Jeong, JW; Jeong, YY; Jin, HJ; Jung, JW; Kang, DY; Kang, HR; Kang, MG; Kim, CW; Kim, HK; Kim, JH; Kim, MH; Kim, MS; Kim, MY; Kim, S; Kim, SH; Koh, YI; Kwon, YE; La, HO; Lee, J; Lee, JK; Lee, SE; Lee, SM; Lee, SY; Lee, YW; Nam, YH; Park, CS; Park, HK; Park, JW; Park, SJ; Sim, DW; Yang, MS; Ye, YM; Yun, J	1
Brett, AS; Goodman, CW	1
Chen, WW; Chien, MY; Chiou, MH; Chu, CY; Huang, PW	1
Chen, C; Chen, X; Chi, L; Guo, X; Guo, Z; He, J; Liang, J; Wei, L; Ye, X; Zheng, Y; Zhou, W	1

Reviews

26 review(s) available for carbamazepine and allopurinol

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Human leukocyte antigens and drug hypersensitivity. Current opinion in allergy and clinical immunology, 2007, Volume: 7, Issue:4 Topics: Allopurinol; Carbamazepine; Dideoxynucleosides; Drug Eruptions; Drug Hypersensitivity; Genetic Predisposition to Disease; HLA Antigens; HLA-B Antigens; Humans; Pharmacogenetics; Stevens-Johnson Syndrome	2007
[Drug-induced hypersensitivity syndrome: DIHS]. Arerugi = [Allergy], 2007, Volume: 56, Issue:11 Topics: Allopurinol; Anticonvulsants; Carbamazepine; Drug Eruptions; Drug Hypersensitivity; Herpesvirus 6, Human; Humans; Solvents; Sulfasalazine; Syndrome; T-Lymphocytes; Trichloroethylene; Virus Activation	2007
Genetic markers and danger signals in stevens-johnson syndrome and toxic epidermal necrolysis. Allergology international : official journal of the Japanese Society of Allergology, 2010, Volume: 59, Issue:4 Topics: Allopurinol; Apoptosis; Biomarkers; Carbamazepine; Cytotoxicity, Immunologic; Genetic Predisposition to Disease; Granzymes; HLA-B Antigens; HLA-B15 Antigen; Humans; Keratinocytes; Killer Cells, Natural; Polymorphism, Genetic; Stevens-Johnson Syndrome; T-Lymphocytes, Cytotoxic	2010
[Exploratory study on biomarkers associated with severe cutaneous adverse reactions]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2011, Volume: 131, Issue:2 Topics: Allopurinol; Carbamazepine; HLA-B Antigens; Humans; Pharmacogenetics; Racial Groups; Stevens-Johnson Syndrome; T-Lymphocytes	2011
Pharmacogenetics of cutaneous adverse drug reactions. The Journal of dermatology, 2011, Volume: 38, Issue:3 Topics: Allopurinol; Anti-Retroviral Agents; Anticonvulsants; Asian People; Carbamazepine; Drug Eruptions; Enzyme Inhibitors; HLA-B Antigens; Humans; Pharmacogenetics; Stevens-Johnson Syndrome; White People	2011
The DRESS syndrome: a literature review. The American journal of medicine, 2011, Volume: 124, Issue:7 Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Allopurinol; Carbamazepine; Diagnosis, Differential; Drug Eruptions; Eosinophilia; Exanthema Subitum; Female; Fever; Herpesvirus 6, Human; Humans; Lymphatic Diseases; Male; Middle Aged; Syndrome; Treatment Outcome	2011
Drug hypersensitivity and human leukocyte antigens of the major histocompatibility complex. Annual review of pharmacology and toxicology, 2012, Volume: 52 Topics: Alleles; Allopurinol; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; HLA Antigens; Humans; Major Histocompatibility Complex; Pharmacogenetics; Polymorphism, Genetic; T-Lymphocytes	2012
HLA alleles and drug hypersensitivity reactions. International journal of immunogenetics, 2012, Volume: 39, Issue:2 Topics: Alleles; Allopurinol; Anti-HIV Agents; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Gene Frequency; Genetic Testing; HLA-B Antigens; HLA-B15 Antigen; Humans; Pharmacogenetics; Stevens-Johnson Syndrome	2012
Human leukocyte antigens (HLA) associated drug hypersensitivity: consequences of drug binding to HLA. Allergy, 2012, Volume: 67, Issue:11 Topics: Alleles; Allopurinol; Carbamazepine; Drug Hypersensitivity; HLA Antigens; HLA-B Antigens; Humans; Receptors, Antigen, T-Cell; T-Lymphocytes	2012
Pharmacogenomics of severe cutaneous adverse reactions and drug-induced liver injury. Journal of human genetics, 2013, Volume: 58, Issue:6 Topics: Alleles; Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Azetidines; Benzylamines; Carbamazepine; Chemical and Drug Induced Liver Injury; Diclofenac; Dideoxynucleosides; Drug Hypersensitivity; Floxacillin; Genetic Markers; HLA Antigens; HLA-A Antigens; HLA-B Antigens; HLA-DQ alpha-Chains; Humans; Lapatinib; Pharmacogenetics; Quinazolines; Skin; Stevens-Johnson Syndrome; Ticlopidine	2013
[The associations between idiosyncratic adverse drug reactions and HLA alleles and their underlying mechanism]. Yao xue xue bao = Acta pharmaceutica Sinica, 2013, Volume: 48, Issue:6 Topics: Alleles; Allopurinol; Anti-HIV Agents; Anticonvulsants; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity Syndrome; Drug-Related Side Effects and Adverse Reactions; Enzyme Inhibitors; Genome-Wide Association Study; HLA Antigens; HLA-B Antigens; HLA-B15 Antigen; Humans; Stevens-Johnson Syndrome	2013
Genotyping for severe drug hypersensitivity. Current allergy and asthma reports, 2014, Volume: 14, Issue:3 Topics: Allopurinol; Amoxicillin-Potassium Clavulanate Combination; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Genotype; HLA-B Antigens; Humans; Nevirapine; Pharmacogenetics; Protein Conformation; Stevens-Johnson Syndrome	2014
Pharmacogenetic markers of severe cutaneous adverse drug reactions. Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2014, Volume: 149, Issue:2 Topics: Allopurinol; Anti-HIV Agents; Anticonvulsants; Biomarkers; Carbamazepine; Dideoxynucleosides; Drug Eruptions; Drug Hypersensitivity Syndrome; Enzyme Inhibitors; Genes, MHC Class I; Genome-Wide Association Study; Genotype; HLA Antigens; Humans; Nevirapine; Pharmacogenetics; Polymorphism, Single Nucleotide; Stevens-Johnson Syndrome	2014
HLA associations and clinical implications in T-cell mediated drug hypersensitivity reactions: an updated review. Journal of immunology research, 2014, Volume: 2014 Topics: Alleles; Allopurinol; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity Syndrome; Gene Expression; Genetic Predisposition to Disease; HLA Antigens; Humans; Stevens-Johnson Syndrome; T-Lymphocytes	2014
[Pharmacogenetic research in the association between human leukocyte antigen and adverse drug reactions]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2014, Volume: 39, Issue:7 Topics: Allopurinol; Carbamazepine; Dideoxynucleosides; Drug-Related Side Effects and Adverse Reactions; Genome-Wide Association Study; HLA Antigens; Humans; Pharmacogenetics	2014
Clinical application of pharmacogenomics: the example of HLA-based drug-induced toxicity. Public health genomics, 2014, Volume: 17, Issue:5-6 Topics: Acute Generalized Exanthematous Pustulosis; Alleles; Allopurinol; Anticonvulsants; Antimetabolites; Asian People; Carbamazepine; Drug Hypersensitivity Syndrome; Histocompatibility Antigens Class I; Histocompatibility Antigens Class II; Humans; Pharmacogenetics; Polymorphism, Genetic; Stevens-Johnson Syndrome	2014
Evolving models of the immunopathogenesis of T cell-mediated drug allergy: The role of host, pathogens, and drug response. The Journal of allergy and clinical immunology, 2015, Volume: 136, Issue:2 Topics: Allopurinol; B-Lymphocytes; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Gene Expression Regulation; Genetic Loci; HLA Antigens; Humans; Models, Immunological; Pharmacogenetics; Stevens-Johnson Syndrome; T-Lymphocytes; Virus Diseases	2015
A review of toxic epidermal necrolysis management in Japan. Allergology international : official journal of the Japanese Society of Allergology, 2017, Volume: 66, Issue:1 Topics: Allopurinol; Carbamazepine; Female; HLA-B Antigens; HLA-B15 Antigen; Humans; Japan; Male; Stevens-Johnson Syndrome; Sulfonamides	2017
Severe Cutaneous Adverse Reactions: The Pharmacogenomics from Research to Clinical Implementation. International journal of molecular sciences, 2016, Nov-15, Volume: 17, Issue:11 Topics: Allopurinol; Anti-HIV Agents; Anticonvulsants; Biomarkers; Carbamazepine; Dideoxynucleosides; Genetic Markers; Gout Suppressants; HLA-B Antigens; Humans; Inactivation, Metabolic; Pharmacogenetics; Precision Medicine; Prognosis; Safety-Based Drug Withdrawals; Stevens-Johnson Syndrome	2016
Pharmacogenetics of hypersensitivity drug reactions. Therapie, 2017, Volume: 72, Issue:2 Topics: Allopurinol; Anticonvulsants; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Enzyme Inhibitors; Genetic Predisposition to Disease; HLA Antigens; Humans; Pharmacogenetics; Reverse Transcriptase Inhibitors	2017
Recent advances in the understanding of severe cutaneous adverse reactions. The British journal of dermatology, 2017, Volume: 177, Issue:5 Topics: Allopurinol; Anticonvulsants; beta-Lactams; Carbamazepine; Cephalosporins; Dideoxynucleosides; Drug Eruptions; Drug Interactions; Herpesviridae Infections; Humans; Leukocytes, Mononuclear; Pharmacogenetics; Prospective Studies; Skin Tests; T-Lymphocytes; Virus Activation; Virus Latency	2017
An update on HLA alleles associated with adverse drug reactions. Drug metabolism and personalized therapy, 2017, 05-24, Volume: 32, Issue:2 Topics: Alleles; Allopurinol; Carbamazepine; Dideoxynucleosides; Drug-Related Side Effects and Adverse Reactions; Economics, Pharmaceutical; HLA Antigens; Humans; Nevirapine	2017
The role of HLA genes in pharmacogenomics: unravelling HLA associated adverse drug reactions. Immunogenetics, 2017, Volume: 69, Issue:8-9 Topics: Allopurinol; Carbamazepine; Drug-Related Side Effects and Adverse Reactions; Haptens; HLA Antigens; Humans; Pharmacogenetics; Polymorphism, Genetic	2017
Drug-Induced Skin Adverse Reactions: The Role of Pharmacogenomics in Their Prevention. Molecular diagnosis & therapy, 2018, Volume: 22, Issue:3 Topics: Alleles; Allopurinol; Anti-HIV Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Carbamazepine; Dideoxynucleosides; Drug Hypersensitivity; Gene Expression; Genetic Testing; Gout Suppressants; HLA-B Antigens; Humans; Pharmacogenetics; Skin	2018
[Mechanisms of Severe Cutaneous Adverse Reactions and a New Treatment Strategy]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan, 2019, Volume: 139, Issue:12 Topics: Acetaminophen; Adrenal Cortex Hormones; Allopurinol; Antigens, Differentiation, T-Lymphocyte; Carbamazepine; CD8-Positive T-Lymphocytes; Cyclosporine; Epidermis; Etanercept; Fas Ligand Protein; HLA Antigens; Humans; Immunoglobulins, Intravenous; Immunosuppressive Agents; Japan; Lamotrigine; Plasma Exchange; Stevens-Johnson Syndrome; Tumor Necrosis Factor-alpha	2019

Trials

2 trial(s) available for carbamazepine and allopurinol

Article	Year
Effects of epilepsy and antiepileptic drugs on nitric oxide, lipid peroxidation and xanthine oxidase system in children with idiopathic epilepsy. Seizure, 2011, Volume: 20, Issue:2 Topics: Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Humans; Lipid Peroxidation; Male; Nitric Oxide; Oxcarbazepine; Valproic Acid; Xanthine Oxidase	2011
Comprehensive assessment of T cell receptor β repertoire in Stevens-Johnson syndrome/toxic epidermal necrolysis patients using high-throughput sequencing. Molecular immunology, 2019, Volume: 106 Topics: Allopurinol; Carbamazepine; Female; High-Throughput Nucleotide Sequencing; Humans; Male; Methazolamide; Receptors, Antigen, T-Cell, alpha-beta; Stevens-Johnson Syndrome	2019

Other Studies

46 other study(ies) available for carbamazepine and allopurinol

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogPoct: a tool for lipophilicity determination in drug discovery. Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. PloS one, 2016, Volume: 11, Issue:10 Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat	2016
Effects of acute carbamazepine administration on haem metabolism in rat liver. Biochemical pharmacology, 1992, Apr-01, Volume: 43, Issue:7 Topics: 5-Aminolevulinate Synthetase; Allopurinol; Animals; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Enzyme Induction; Heme; Indoleamine-Pyrrole 2,3,-Dioxygenase; Liver; Male; Porphyrias; Rats; Rats, Inbred Strains; Tryptophan Oxygenase	1992
Plasma exchange (PE) treatment in drug-induced toxic epidermal necrolysis (TEN). The International journal of artificial organs, 1991, Volume: 14, Issue:10 Topics: Aged; Allopurinol; Amoxicillin; Carbamazepine; Child; Ciprofloxacin; Humans; Male; Mefenamic Acid; Middle Aged; Plasma Exchange; Skin; Stevens-Johnson Syndrome; Tetanus Toxoid	1991
Interactions of oral antibiotics and common chronic medications. Geriatrics, 1987, Volume: 42, Issue:1 Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Allopurinol; Ampicillin; Antacids; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Digoxin; Drug Combinations; Drug Interactions; Erythromycin; Humans; Sulfamethoxazole; Sulfonamides; Sulfonylurea Compounds; Tetracycline; Theophylline; Trimethoprim; Trimethoprim, Sulfamethoxazole Drug Combination; Warfarin	1987
Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis: a case-control study. Internal medicine journal, 2005, Volume: 35, Issue:3 Topics: Adult; Allopurinol; Analgesics, Non-Narcotic; Anticonvulsants; Antimetabolites; Carbamazepine; Case-Control Studies; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Phenytoin; Risk Assessment; Stevens-Johnson Syndrome; Taiwan	2005
Clinicopathological features and prognosis of drug rash with eosinophilia and systemic symptoms: a study of 30 cases in Taiwan. Journal of the European Academy of Dermatology and Venereology : JEADV, 2008, Volume: 22, Issue:9 Topics: Adolescent; Adult; Aged; Allopurinol; Carbamazepine; Eosinophilia; Exanthema; Female; Humans; Hydrocortisone; Male; Middle Aged; Prednisolone; Prognosis; Taiwan; Treatment Outcome	2008
HLA-B allele associations with certain drugs are not confirmed in Japanese patients with severe cutaneous drug reactions. Acta dermato-venereologica, 2008, Volume: 88, Issue:6 Topics: Alleles; Allopurinol; Anticonvulsants; Asian People; Carbamazepine; Chemical and Drug Induced Liver Injury; Drug Hypersensitivity; Gout Suppressants; HLA-B Antigens; Humans; Japan; Stevens-Johnson Syndrome; Syndrome; Virus Activation	2008
Chronic peritoneal dialysis in a 4-year-old boy with Lesch-Nyhan disease. Pediatric nephrology (Berlin, Germany), 2009, Volume: 24, Issue:5 Topics: Allopurinol; Carbamazepine; Child, Preschool; DNA Mutational Analysis; Erythrocytes; Family Health; Female; Gout Suppressants; Humans; Hypoxanthine Phosphoribosyltransferase; Intellectual Disability; Lesch-Nyhan Syndrome; Male; Mutation; Peritoneal Dialysis; Treatment Outcome	2009
Prevention of severe cutaneous adverse drug reactions: the emerging value of pharmacogenetic screening. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2010, Mar-23, Volume: 182, Issue:5 Topics: Adult; Alleles; Allopurinol; Anticonvulsants; Asian People; Carbamazepine; China; Cyclosporine; Drug Hypersensitivity; Genetic Predisposition to Disease; Genetic Testing; Gout Suppressants; HLA-B Antigens; Humans; Immunization, Passive; Immunosuppressive Agents; Keratoconjunctivitis; Male; Stevens-Johnson Syndrome; Urethritis	2010
Hypersensitivity to amoxicillin after drug rash with eosinophilia and systemic symptoms (DRESS) to carbamazepine and allopurinol: a possible co-sensitization. British journal of clinical pharmacology, 2010, Volume: 70, Issue:2 Topics: Adult; Allopurinol; Amoxicillin; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Drug Hypersensitivity; Enzyme Inhibitors; Eosinophilia; Exanthema; Humans; Male; Middle Aged	2010
[Six cases of spring DRESS]. Annales de dermatologie et de venereologie, 2012, Volume: 139, Issue:1 Topics: Acute Kidney Injury; Adult; Aged; Allopurinol; Amoxicillin; Anti-Bacterial Agents; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytomegalovirus; Cytomegalovirus Infections; Disease Outbreaks; Drug Eruptions; Epstein-Barr Virus Infections; Female; France; Herpesvirus 4, Human; Herpesvirus 6, Human; Herpesvirus 7, Human; Humans; Hypereosinophilic Syndrome; Imidazoles; Immunocompromised Host; Male; Middle Aged; Models, Biological; Roseolovirus Infections; Seasons; Trimethoprim, Sulfamethoxazole Drug Combination; Virus Activation	2012
Genetics and the potential for predictive tests in adverse drug reactions. Chemical immunology and allergy, 2012, Volume: 97 Topics: Allopurinol; Anti-Bacterial Agents; Anti-HIV Agents; Anticonvulsants; Antimetabolites; Biomarkers; Carbamazepine; Chemical and Drug Induced Liver Injury; Dideoxynucleosides; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Genome-Wide Association Study; HLA Antigens; HLA-A Antigens; HLA-B Antigens; Humans; Immune System; Predictive Value of Tests; Stevens-Johnson Syndrome	2012
[DRESS syndrome]. La Tunisie medicale, 2012, Volume: 90, Issue:10 Topics: Adolescent; Adult; Allopurinol; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Carbamazepine; Child; Drug Combinations; Drug Eruptions; Eosinophilia; Exanthema; Female; Glucosamine; Gout Suppressants; Humans; Male; Middle Aged; Pruritus; Retrospective Studies; Sulfasalazine; Syndrome; Trimethoprim, Sulfamethoxazole Drug Combination; Young Adult	2012
Histopathology of drug rash with eosinophilia and systemic symptoms syndrome: a morphological and phenotypical study. The British journal of dermatology, 2015, Volume: 173, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Bacterial Agents; B-Lymphocytes; Carbamazepine; Drug Hypersensitivity Syndrome; Exanthema; Female; Gout Suppressants; Humans; Immunohistochemistry; Male; Middle Aged; Minocycline; Phenotype; Retrospective Studies; Sulfasalazine; T-Lymphocytes; Trimethoprim, Sulfamethoxazole Drug Combination; Young Adult	2015
Research on Susceptible Genes and Immunological Pathogenesis of Cutaneous Adverse Drug Reactions in Chinese Hans. The journal of investigative dermatology. Symposium proceedings, 2015, Volume: 17, Issue:1 Topics: Allopurinol; Amoxicillin; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Asian People; Biomarkers; Carbamazepine; Carbonic Anhydrase Inhibitors; Case-Control Studies; Cephalosporins; China; Cytokines; Drug Eruptions; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotyping Techniques; Gout Suppressants; HLA-B Antigens; Humans; Methazolamide; Polymorphism, Single Nucleotide; Sulfasalazine	2015
HLA Allele Frequencies in 5802 Koreans: Varied Allele Types Associated with SJS/TEN According to Culprit Drugs. Yonsei medical journal, 2016, Volume: 57, Issue:1 Topics: Adult; Aged; Alleles; Allopurinol; Anticonvulsants; Asian People; Carbamazepine; Case-Control Studies; Drug-Related Side Effects and Adverse Reactions; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; HLA-B Antigens; Humans; Lamotrigine; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Republic of Korea; Retrospective Studies; Risk Factors; Stevens-Johnson Syndrome; Triazines	2016
Trends in culprit drugs and clinical entities in cutaneous adverse drug reactions: a retrospective study. Cutaneous and ocular toxicology, 2017, Volume: 36, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Carbamazepine; Cephalosporins; Child; Child, Preschool; China; Drug Eruptions; Female; Fluoroquinolones; Humans; Infant; Male; Medicine, Chinese Traditional; Middle Aged; Penicillins; Young Adult	2017
Tailoring of recommendations to reduce serious cutaneous adverse drug reactions: a pharmacogenomics approach. Pharmacogenomics, 2017, Volume: 18, Issue:9 Topics: Alleles; Allopurinol; Carbamazepine; Cost-Benefit Analysis; Drug-Related Side Effects and Adverse Reactions; HLA-B Antigens; Humans; Pharmacogenetics; Singapore; Skin; Skin Diseases	2017
Clinical features of drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome: a study of 25 patients in Korea. International journal of dermatology, 2017, Volume: 56, Issue:9 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Allopurinol; Anticonvulsants; Antitubercular Agents; Carbamazepine; Drug Hypersensitivity Syndrome; Eosinophilia; Female; Glucocorticoids; Gout Suppressants; Humans; Immunoglobulins, Intravenous; Immunologic Factors; Male; Methylprednisolone; Middle Aged; Prednisone; Republic of Korea; Retrospective Studies; Severity of Illness Index; Thrombocytopenia; Time Factors; Young Adult	2017
Clinical, Viral and Genetic Characteristics of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) in Shanghai, China. Acta dermato-venereologica, 2018, Apr-16, Volume: 98, Issue:4 Topics: Adrenal Cortex Hormones; Adult; Aged; Aged, 80 and over; Allopurinol; Carbamazepine; China; DNA, Viral; Drug Hypersensitivity Syndrome; Female; Genetic Predisposition to Disease; Herpesvirus 4, Human; Herpesvirus 6, Human; HLA-B Antigens; HLA-DRB1 Chains; Hospital Costs; Humans; Immunoglobulins, Intravenous; Length of Stay; Male; Middle Aged; Patient Admission; Phenotype; Retrospective Studies; Risk Factors; Sulfasalazine; Time Factors; Virus Activation; Young Adult	2018
Incidence of Stevens-Johnson syndrome following combination drug use of allopurinol, carbamazepine and phenytoin in Taiwan: A case-control study. The Journal of dermatology, 2018, Volume: 45, Issue:9 Topics: Adult; Aged; Allopurinol; Anticonvulsants; Carbamazepine; Case-Control Studies; Drug Combinations; Epilepsy; Female; Gout; Gout Suppressants; Humans; Incidence; Male; Middle Aged; Phenytoin; Stevens-Johnson Syndrome; Taiwan	2018
Analysis of Individual Case Safety Reports of Severe Cutaneous Adverse Reactions in Korea. Yonsei medical journal, 2019, Volume: 60, Issue:2 Topics: Adverse Drug Reaction Reporting Systems; Allopurinol; Anti-Bacterial Agents; Anticonvulsants; Carbamazepine; Drug Labeling; Female; Humans; Male; Middle Aged; Republic of Korea; Skin Diseases; Stevens-Johnson Syndrome	2019
Knowledge and opinions among Canadian academic physicians regarding genetic screening to prevent severe cutaneous adverse drug reactions. Journal of the American Academy of Dermatology, 2019, Volume: 81, Issue:6 Topics: Academies and Institutes; Allopurinol; Attitude of Health Personnel; Canada; Carbamazepine; Drug Eruptions; Genetic Testing; Health Knowledge, Attitudes, Practice; Humans; Severity of Illness Index; Stevens-Johnson Syndrome	2019
Global Frequencies of Clinically Important HLA Alleles and Their Implications For the Cost-Effectiveness of Preemptive Pharmacogenetic Testing. Clinical pharmacology and therapeutics, 2021, Volume: 109, Issue:1 Topics: Alleles; Allopurinol; Asia; Carbamazepine; Cost-Benefit Analysis; Dideoxynucleosides; Drug Hypersensitivity; Europe; Genetic Testing; Genotype; HLA Antigens; Humans; Pharmacogenetics; Pharmacogenomic Testing	2021
A Nationwide Study of Severe Cutaneous Adverse Reactions Based on the Multicenter Registry in Korea. The journal of allergy and clinical immunology. In practice, 2021, Volume: 9, Issue:2 Topics: Allopurinol; Carbamazepine; Humans; Registries; Republic of Korea; Stevens-Johnson Syndrome	2021
Race and Pharmacogenomics-Personalized Medicine or Misguided Practice? JAMA, 2021, Feb-16, Volume: 325, Issue:7 Topics: Allopurinol; Asian People; Carbamazepine; Genetic Testing; HLA-B Antigens; HLA-B15 Antigen; Humans; Pharmacogenetics; Precision Medicine; Racial Groups; United States; United States Food and Drug Administration	2021
Analysis of severe cutaneous adverse reactions (SCARs) in Taiwan drug-injury relief system: 18-year results. Journal of the Formosan Medical Association = Taiwan yi zhi, 2022, Volume: 121, Issue:8 Topics: Allopurinol; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticonvulsants; Carbamazepine; Cicatrix; Humans; Phenytoin; Retrospective Studies; Stevens-Johnson Syndrome; Taiwan	2022
Drug-induced Stevens-Johnson syndrome: a disproportionality analysis from the pharmacovigilance database of the World Health Organization. Expert opinion on drug safety, 2022, Volume: 21, Issue:8 Topics: Allopurinol; Carbamazepine; Humans; Pharmacovigilance; Phenytoin; Retrospective Studies; Stevens-Johnson Syndrome; World Health Organization	2022