carbamazepine has been researched along with 10,11-dihydro-10,11-dihydroxy-5h-dibenzazepine-5-carboxamide in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (28.57) | 18.7374 |
| 1990's | 23 (54.76) | 18.2507 |
| 2000's | 5 (11.90) | 29.6817 |
| 2010's | 2 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gorkov, VA; Kudriakova, TB; Rozova, GI; Sirota, LA | 1 |
| Boas, J; Dam, M; Flesch, G; Jensen, PK; Jórgensen, L; Mogensen, PH; Vesterager, A | 1 |
| Campestrini, J; Godbillon, J; Le Clanche, V; Lecaillon, JB; Rouan, MC | 1 |
| Hosoda, N; Miura, H; Shirai, H; Sunaoshi, W; Takanashi, S | 1 |
| Chan, KK; Riad, LE; Sawchuk, RJ | 2 |
| Forsythe, WI; Hartley, R; Lucock, MD; McLain, B; Ng, PC | 1 |
| Bowmer, CJ; Forsythe, WI; Hartley, R; Lucock, MD; McLain, B; Ng, PC | 1 |
| De Salamanca, RE; Diaz-Obregón, C; Muñoz, JJ; Timoneda, FL | 1 |
| Paar, WD; von Unruh, GE | 1 |
| Bittencourt, PR | 1 |
| Chelberg, RD; Gunawan, S; Treiman, DM | 1 |
| Riad, LE; Sawchuk, RJ | 2 |
| Kumps, A; Mardens, Y | 1 |
| Baumann, RJ; Chang, SL; Robbins, DK; Wedlund, PJ | 1 |
| Juergens, U; May, T; Rambeck, B | 1 |
| Friel, PN; van Belle, G | 1 |
| Hekster, YA; Janssen, TJ; Termond, EF; van de Dries, AC; Vree, TB; Wijnands, WJ | 1 |
| Bourgeois, BF; Wad, N | 1 |
| Aucamp, AK; Hundt, HK; Müller, FO | 1 |
| Aucamp, AK; Hundt, HK; Müller, FO; Potgieter, MA | 1 |
| Delgado, MR; Liu, H | 2 |
| Aldigier, JC; Darragon, T; Godbillon, J; Hillion, D; Jungers, P; Kourilsky, O; Lecaillon, JB; Menard, F; Meyer, P; Rouan, MC | 1 |
| Bernus, I; Dickinson, RG; Eadie, MJ; Hooper, WD | 2 |
| Delgado, M; Eggers, CM; Forman, LJ; Iannaccone, ST; Liu, H | 1 |
| Dzeka, T; Ebinger, G; Michotte, Y; Sarre, S; Van Belle, K | 1 |
| McFadyen, ML; Miller, R; Moosa, RS; Rubin, J | 1 |
| Graves, NM; Leppik, IE; Remmel, RP; Wagner, ML | 1 |
| Eto, S; Noda, A; Noda, H; Tanaka, N | 1 |
| Pippenger, CE; Svinarov, DA | 1 |
| Brekelmans, GJ; Edelbroek, PM; Rademaker, RV; Saris, LA; van der Linden, GJ | 1 |
| Härtter, S; Hiemke, C; Jensen, B; Leal, M; Unger, K; Weigmann, H | 1 |
| Bialer, M; Perucca, E; Sintov, A; Volosov, A; Xiaodong, S; Yagen, B | 1 |
| Guénault, N; Odou, P; Robert, H | 1 |
| Asahara, H; Koizumi, T; Mochizuki, E; Oshima, T | 1 |
| Divanoglou, D; Gabrieli, C; Kanaze, FI; Kazis, D; Kimiskidis, V; Niopas, I; Spanakis, M | 1 |
| Corso, G; D'Apolito, O; Paglia, G | 1 |
| Casellas, C; Fenet, H; Gomez, E; Hillaire-Buys, D; Li, Z; Mahjoub, O; Mathieu, O | 1 |
| Brezina, E; Meyer, J; Mückter, H; Prasse, C; Ternes, TA | 1 |
8 trial(s) available for carbamazepine and 10,11-dihydro-10,11-dihydroxy-5h-dibenzazepine-5-carboxamide
| Article | Year |
|---|---|
Gas chromatographic/mass spectrometric assays for oxcarbazepine and its main metabolites, 10-hydroxy-carbazepine and carbazepine-10,11-trans-diol.
Topics: Anticonvulsants; Biological Availability; Carbamazepine; Clinical Trials as Topic; Epilepsy; Gas Chromatography-Mass Spectrometry; Humans; Oxcarbazepine | 1986 |
Oxcarbazepine and spasticity: further observations.
Topics: Adult; Anticonvulsants; Carbamazepine; Clinical Trials as Topic; Double-Blind Method; Epilepsy; Female; Humans; Male; Middle Aged; Muscle Spasticity; Oxcarbazepine | 1988 |
Influence of sex, age, weight, and carbamazepine dose on serum concentrations, concentration ratios, and level/dose ratios of carbamazepine and its metabolites.
Topics: Aging; Body Weight; Carbamazepine; Child; Child, Preschool; Dose-Response Relationship, Drug; Epilepsy; Female; Humans; Male; Sex Factors | 1994 |
Effect of felbamate on carbamazepine and its major metabolites.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Double-Blind Method; Drug Interactions; Epilepsy; Felbamate; Female; Humans; Male; Middle Aged; Phenylcarbamates; Phenytoin; Propylene Glycols | 1993 |
Relationships between carbamazepine-diol, carbamazepine-epoxide, and carbamazepine total and free steady-state concentrations in epileptic patients: the influence of age, sex, and comedication.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Epilepsy; Female; Humans; Infant; Male; Middle Aged; Phenobarbital; Protein Binding; Sex Factors | 1996 |
The mechanism of the carbamazepine-valproate interaction in humans.
Topics: Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Valproic Acid | 1997 |
Micellar electrokinetic capillary chromatography for therapeutic drug monitoring of carbamazepine and its main metabolites.
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Electrophoresis, Capillary; Humans | 1998 |
Development and validation of a high performance liquid chromatographic method for the determination of oxcarbazepine and its main metabolites in human plasma and cerebrospinal fluid and its application to pharmacokinetic study.
Topics: Acetonitriles; Amines; Anticonvulsants; Biotransformation; Buffers; Calibration; Carbamazepine; Chromatography, High Pressure Liquid; Drug Monitoring; Epilepsy; Guidelines as Topic; Humans; Linear Models; Oxcarbazepine; Phosphates; Potassium Compounds; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Solvents; Spectrophotometry, Ultraviolet | 2007 |
34 other study(ies) available for carbamazepine and 10,11-dihydro-10,11-dihydroxy-5h-dibenzazepine-5-carboxamide
| Article | Year |
|---|---|
Autoinduction and steady-state pharmacokinetics of carbamazepine and its major metabolites.
Topics: Adult; Carbamazepine; Female; Humans; Male; Middle Aged | 1992 |
Effects of dextropropoxyphene on the steady-state kinetics of oxcarbazepine and its metabolites.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dextropropoxyphene; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Oxcarbazepine; Trigeminal Neuralgia | 1992 |
Automated microanalysis of carbamazepine and its epoxide and trans-diol metabolites in plasma by column liquid chromatography.
Topics: Autoanalysis; Carbamazepine; Chromatography, Liquid; Humans; Indicators and Reagents; Microchemistry; Specimen Handling; Spectrophotometry, Ultraviolet | 1992 |
Influence of concurrent administration of sodium valproate on the plasma concentrations of carbamazepine and its epoxide and diol metabolites.
Topics: Adolescent; Adult; Carbamazepine; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Valproic Acid | 1991 |
Determination of the relative formation and elimination clearance of two major carbamazepine metabolites in humans: a comparison between traditional and pooled sample analysis.
Topics: Administration, Oral; Adult; Carbamazepine; Humans; Male; Models, Biological | 1991 |
Daily variations in steady-state plasma concentrations of carbamazepine and its metabolites in epileptic children.
Topics: Adolescent; Carbamazepine; Child; Chromatography, High Pressure Liquid; Epilepsy; Female; Humans; Male | 1991 |
Factors influencing plasma level/dose ratios of carbamazepine and its major metabolites in epileptic children.
Topics: Adolescent; Age Factors; Carbamazepine; Child; Epilepsy; Humans; Regression Analysis; Time Factors | 1990 |
The effect of clobazam on steady state plasma concentrations of carbamazepine and its metabolites.
Topics: Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Carbamazepine; Chromatography, High Pressure Liquid; Clobazam; Drug Therapy, Combination; Epilepsy; Humans | 1990 |
Simultaneous high-performance liquid chromatographic determination of carbamazepine and its principal metabolites in human plasma and urine.
Topics: Biotransformation; Carbamazepine; Chromatography, High Pressure Liquid; Humans | 1988 |
Simultaneous determination of carbamazepine and its epoxide and transdiol metabolites in plasma by microbore liquid chromatography.
Topics: Adult; Carbamazepine; Chromatography, Liquid; Clonazepam; Humans; Male; Phenobarbital; Phenytoin; Quality Control; Statistics as Topic; Therapeutic Equivalency | 1988 |
Cross-reactivity assessment of oxcarbazepine and its metabolites in the EMIT assay of carbamazepine plasma levels.
Topics: Biotransformation; Carbamazepine; Cross Reactions; Humans; Immunoenzyme Techniques; Oxcarbazepine | 1986 |
Quantitation of trans-10,11-dihydroxy-10,11-dihydrocarbamazepine in human urine by high-performance liquid chromatography.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Drug Stability; Glucuronidase; Humans; Hydrolysis; Indicators and Reagents | 1987 |
Serum concentrations of carbamazepine and its epoxide and diol metabolites in epileptic patients: the influence of dose and comedication.
Topics: Adult; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Regression Analysis | 1987 |
Problem of spurious correlation in the evaluation of steady-state carbamazepine levels using metabolite data.
Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Middle Aged; Statistics as Topic | 1986 |
Clinical pharmacokinetics of carbamazepine and its epoxy and hydroxy metabolites in humans after an overdose.
Topics: Adult; Carbamazepine; Female; Humans; Hydrolysis; Kidney; Kinetics; Male; Middle Aged; Protein Binding; Time Factors | 1986 |
Carbamazepine-10,11-diol steady-state serum levels and renal excretion during carbamazepine therapy in adults and children.
Topics: Adult; Biotransformation; Carbamazepine; Child; Epilepsy; Female; Humans; Kinetics; Male | 1984 |
Pharmacokinetic aspects of carbamazepine and its two major metabolites in plasma during overdosage.
Topics: Biotransformation; Carbamazepine; Humans; Intestinal Absorption; Kinetics | 1983 |
Carbamazepine and its major metabolites in plasma: a summary of eight years of therapeutic drug monitoring.
Topics: Black People; Carbamazepine; Epilepsy; Humans; White People | 1983 |
The effect of renal impairment on the pharmacokinetics of oxcarbazepine and its metabolites.
Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Female; Humans; Kidney Diseases; Male; Middle Aged; Oxcarbazepine | 1994 |
Early stage autoinduction of carbamazepine metabolism in humans.
Topics: Acridines; Adult; Carbamazepine; Confidence Intervals; Humans; Male; Oxidation-Reduction | 1994 |
The influence of polytherapy on the relationships between serum carbamazepine and its metabolites in epileptic children.
Topics: Aging; Anticonvulsants; Body Weight; Carbamazepine; Child; Chromatography, High Pressure Liquid; Drug Interactions; Drug Therapy, Combination; Epilepsy; Female; Humans; Male; Spectrophotometry, Ultraviolet; Valproic Acid | 1994 |
Determination of total and free carbamazepine and the principal metabolites in serum by high-performance liquid chromatography with photodiode-array detection.
Topics: Carbamazepine; Child; Chromatography, High Pressure Liquid; Epilepsy; Humans; Spectrophotometry, Ultraviolet; Ultrafiltration | 1993 |
In vitro and in vivo microdialysis calibration for the measurement of carbamazepine and its metabolites in rat brain tissue using the internal reference technique.
Topics: Animals; Brain; Calibration; Carbamazepine; In Vitro Techniques; Male; Microdialysis; Rats; Rats, Wistar; Reference Standards | 1993 |
Carbamazepine and its metabolites in neuralgias: concentration-effect relations.
Topics: Adult; Aged; Aged, 80 and over; Carbamazepine; Chromatography, High Pressure Liquid; Enzyme Multiplied Immunoassay Technique; Female; Humans; Male; Middle Aged; Neuralgia; Regression Analysis | 1993 |
Transient steady-state analysis: application in the determination of the relative formation and elimination clearances of two major carbamazepine metabolites in humans.
Topics: Adult; Carbamazepine; Chromatography, High Pressure Liquid; Half-Life; Humans; Male; Models, Biological | 1993 |
Chiral separation of 10,11-dihydro-10, 11-trans-dihydroxycarbamazepine, a metabolite of carbamazepine with two asymmetric carbons, in human serum.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Epilepsy; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Stereoisomerism | 1996 |
High-performance liquid chromatographic determination of carbamazepine and metabolites in human hair.
Topics: Adult; Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Hair; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 1997 |
A partial area difference analysis for estimating elimination rate constants and distribution volumes of metabolites.
Topics: Adult; Anticonvulsants; Carbamazepine; Humans | 1998 |
Simultaneous stereoselective high-performance liquid chromatographic determination of 10-hydroxycarbazepine and its metabolite carbamazepine-10,11-trans-dihydrodiol in human urine.
Topics: Carbamazepine; Chromatography, High Pressure Liquid; Humans; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet | 2000 |
Increase in dihydroxycarbamazepine serum levels in patients co-medicated with oxcarbazepine and lamotrigine.
Topics: Anticonvulsants; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Humans; Lamotrigine; Oxcarbazepine; Retrospective Studies; Triazines | 2003 |
Two conformers of 10,11-dihydro-5H-dibenzo[a,d]cycloheptene spiro-linked with homobenzoquinone epoxide.
Topics: Carbamazepine; Crystallography, X-Ray; Cycloheptanes; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation | 2006 |
The accuracy of oxcarbazepine (OXC) quantification by a liquid chromatography/tandem mass spectrometry method is influenced by the ion source fragmentation of its metabolite trans-diol-carbazepine (DHD).
Topics: Anticonvulsants; Carbamazepine; Chromatography, High Pressure Liquid; Oxcarbazepine; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry | 2007 |
Carbamazepine, carbamazepine epoxide and dihydroxycarbamazepine sorption to soil and occurrence in a wastewater reuse site in Tunisia.
Topics: Adsorption; Carbamazepine; Soil; Tunisia; Waste Disposal, Fluid; Water Pollutants, Chemical | 2012 |
Investigation and risk evaluation of the occurrence of carbamazepine, oxcarbazepine, their human metabolites and transformation products in the urban water cycle.
Topics: Carbamazepine; Chromatography, Liquid; Cities; Filtration; Groundwater; Humans; Mass Spectrometry; Oxcarbazepine; Risk Assessment; Waste Disposal, Fluid; Wastewater; Water Cycle; Water Pollutants, Chemical | 2017 |