Compounds > carbamates

carbamates and pepstatin

carbamates has been researched along with pepstatin in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
DiMuzio-Mower, J; Gardell, SJ; Huang, Q; Lai, MT; Li, YM; Sardana, MK; Shafer, JA; Shi, XP; Xu, M; Yin, KC1
De Strooper, B; Iwatsubo, T; Kawano, Y; Murakami, D; Nagano, O; Okamoto, I; Saya, H; Tomita, T; Yumoto, E1
Aharony, D; Ghanekar, SV; Greenberg, BD; Jacobs, RT; Liu, X; Shenvi, AB; Tian, G1
Dunn, BM; Goldfarb, NE; Gustchina, A; Li, M; Matúz, K; Namwong, S; Tözsér, J; Wlodawer, A1
Bellio, N; Cagnin, M; Fiorentino, I; Follo, C; Isidoro, C; Ozzano, M1

Other Studies

5 other study(ies) available for carbamates and pepstatin

ArticleYear
Presenilin 1 is linked with gamma-secretase activity in the detergent solubilized state.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, May-23, Volume: 97, Issue:11

    Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Carbamates; Cell Fractionation; Cell Membrane; Cholic Acids; Detergents; Dipeptides; Endopeptidases; HeLa Cells; Humans; Membrane Proteins; Neoplasm Proteins; Pepstatins; Presenilin-1; Protease Inhibitors; Recombinant Fusion Proteins; Solubility; Substrate Specificity

2000
Presenilin-dependent gamma-secretase activity mediates the intramembranous cleavage of CD44.
    Oncogene, 2003, Mar-13, Volume: 22, Issue:10

    Topics: Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Carbamates; Cell Membrane; Central Nervous System Neoplasms; Dipeptides; Embryo, Mammalian; Endopeptidases; Fibroblasts; Glioma; Humans; Hyaluronan Receptors; Leupeptins; Membrane Proteins; Mice; Mice, Knockout; Pepstatins; Presenilin-1; Protease Inhibitors; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured

2003
The mechanism of gamma-secretase: multiple inhibitor binding sites for transition state analogs and small molecule inhibitors.
    The Journal of biological chemistry, 2003, Aug-01, Volume: 278, Issue:31

    Topics: Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Benzodiazepines; Binding Sites; Binding, Competitive; Carbamates; Catalysis; Dipeptides; Endopeptidases; Enzyme Inhibitors; Humans; Kinetics; Mathematics; Pepstatins; Solubility; Sulfonamides; Tritium

2003
Structural and biochemical characterization of the inhibitor complexes of xenotropic murine leukemia virus-related virus protease.
    The FEBS journal, 2011, Volume: 278, Issue:22

    Topics: Animals; Binding Sites; Carbamates; Crystallography, X-Ray; Dimerization; Furans; Mice; Models, Molecular; Pepstatins; Peptide Hydrolases; Protease Inhibitors; Protein Binding; Protein Conformation; Sulfonamides; Xenotropic murine leukemia virus-related virus

2011
Dopamine induces apoptosis in APPswe-expressing Neuro2A cells following Pepstatin-sensitive proteolysis of APP in acid compartments.
    Brain research, 2012, Aug-30, Volume: 1471

    Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Apoptosis; bcl-2-Associated X Protein; Carbamates; Cathepsin D; Cell Line, Tumor; Chloroquine; Dipeptides; Dopamine; Dose-Response Relationship, Drug; Endocytosis; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Humans; In Situ Nick-End Labeling; Lysosomes; Mice; Mitochondrial Membranes; Neuroblastoma; Pepstatins; Phorbol Esters; Protease Inhibitors; Protein Biosynthesis; Proteolysis; RNA, Small Interfering; Transfection

2012