carbamates and midazolam

carbamates has been researched along with midazolam in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's6 (60.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Rekling, JC1
Backman, JT; Kajosaari, LI; Laitila, J; Neuvonen, PJ1
Maren, K; Rojkjaer, L; Skerjanec, A; Wang, J1
German, P; Hui, J; Jain, A; Kearney, BP; Mathias, AA; Murray, BP; Warren, D; Wei, L; West, S1
Cao, Y; Jusko, WJ1
Chang, SY; Cheng, Y; Humphreys, WG; Li, W; Ma, L1
Chun, DY; Einolf, HJ; Gu, H; Sangana, R1
Gaudette, F; Huguet, J; Michaud, V; Turgeon, J1
Bairlein, M; Gerisch, M; Heinig, R; Loewen, S; Nagelschmitz, J1
Hoch, M; Hourcade-Potelleret, F; Sengupta, T1

Trials

3 trial(s) available for carbamates and midazolam

ArticleYear
Investigation of the pharmacokinetic interactions of deferasirox, a once-daily oral iron chelator, with midazolam, rifampin, and repaglinide in healthy volunteers.
    Journal of clinical pharmacology, 2010, Volume: 50, Issue:2

    Topics: Adult; Anesthetics, Intravenous; Aryl Hydrocarbon Hydroxylases; Benzoates; Carbamates; Cross-Over Studies; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Deferasirox; Drug Interactions; Enzyme Inhibitors; Female; Humans; Hypoglycemic Agents; Iron Chelating Agents; Male; Midazolam; Piperidines; Rifampin; Triazoles

2010
Results from Drug-Drug Interaction Studies In Vitro and In Vivo Investigating the Effect of Finerenone on the Pharmacokinetics of Comedications.
    European journal of drug metabolism and pharmacokinetics, 2020, Volume: 45, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Carbamates; Cross-Over Studies; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inducers; Cytochrome P-450 Enzyme Inhibitors; Double-Blind Method; Drug Interactions; Germany; Humans; Isoenzymes; Male; Midazolam; Middle Aged; Mineralocorticoid Receptor Antagonists; Models, Biological; Naphthyridines; Piperidines; Substrate Specificity; Warfarin; Young Adult

2020
Pharmacokinetic drug interactions of asciminib with the sensitive cytochrome P450 probe substrates midazolam, warfarin, and repaglinide in healthy participants.
    Clinical and translational science, 2022, Volume: 15, Issue:6

    Topics: Carbamates; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Healthy Volunteers; Humans; Midazolam; Niacinamide; Piperidines; Pyrazoles; Warfarin

2022

Other Studies

7 other study(ies) available for carbamates and midazolam

ArticleYear
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
    Neuroscience letters, 2003, Jan-02, Volume: 335, Issue:3

    Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid

2003
Metabolism of repaglinide by CYP2C8 and CYP3A4 in vitro: effect of fibrates and rifampicin.
    Basic & clinical pharmacology & toxicology, 2005, Volume: 97, Issue:4

    Topics: Aryl Hydrocarbon Hydroxylases; Bezafibrate; Carbamates; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Fenofibrate; Gemfibrozil; Humans; Hypoglycemic Agents; In Vitro Techniques; Itraconazole; Microsomes, Liver; Midazolam; Paclitaxel; Piperidines; Quercetin; Rifampin

2005
Pharmacokinetics and pharmacodynamics of GS-9350: a novel pharmacokinetic enhancer without anti-HIV activity.
    Clinical pharmacology and therapeutics, 2010, Volume: 87, Issue:3

    Topics: Adolescent; Adult; Anti-HIV Agents; Anti-Retroviral Agents; Carbamates; Cobicistat; Cohort Studies; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Female; Humans; Isoenzymes; Male; Midazolam; Middle Aged; Pharmaceutical Preparations; Thiazoles; Young Adult

2010
Applications of minimal physiologically-based pharmacokinetic models.
    Journal of pharmacokinetics and pharmacodynamics, 2012, Volume: 39, Issue:6

    Topics: Anti-Bacterial Agents; Antibodies, Monoclonal; beta-Lactams; Biological Availability; Carbamates; Codeine; Humans; Kinetics; Liver; Midazolam; Models, Biological; Piperidines; Regional Blood Flow; Verapamil

2012
Application of Static Models to Predict Midazolam Clinical Interactions in the Presence of Single or Multiple Hepatitis C Virus Drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:8

    Topics: Algorithms; Antiviral Agents; Benzazepines; Biotransformation; Carbamates; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inducers; Cytochrome P-450 CYP3A Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Hepatitis C, Chronic; Hepatocytes; Humans; Imidazoles; Indoles; Isoquinolines; Kinetics; Liver; Midazolam; Models, Biological; Nonlinear Dynamics; Pyrrolidines; Risk Assessment; Risk Factors; RNA, Messenger; Sulfonamides; Valine

2016
Evaluation of Clinical Drug Interaction Potential of Clofazimine Using Static and Dynamic Modeling Approaches.
    Drug metabolism and disposition: the biological fate of chemicals, 2018, Volume: 46, Issue:1

    Topics: Antitubercular Agents; Area Under Curve; Carbamates; Clofazimine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Desipramine; Drug Interactions; Humans; Midazolam; Models, Biological; Piperidines; Tuberculosis, Multidrug-Resistant

2018
Development and validation of probe drug cocktails for the characterization of CYP450-mediated metabolism by human heart microsomes.
    Xenobiotica; the fate of foreign compounds in biological systems, 2019, Volume: 49, Issue:2

    Topics: Bupropion; Butyrophenones; Carbamates; Chlorzoxazone; Cytochrome P-450 Enzyme System; Drug Evaluation, Preclinical; Ethanolamines; Humans; Lauric Acids; Microsomes; Midazolam; Myocardium; Oxazines; Piperidines; Tolbutamide

2019