Compounds > carbamates

carbamates and ganstigmine

carbamates has been researched along with ganstigmine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Acerbi, D; Catinella, S; Marchetti, S; Pelizzi, N; Puccini, P; Ventura, P; Zanol, M1
Hutter-Paier, B; Imbimbo, B; Jerkovic, L; Villetti, G; Windisch, M1
Acerbi, D; Catinella, S; Pelizzi, N; Puccini, P; Riccardi, B1
Govoni, S; Mazzucchelli, M; Pietra, C; Porrello, E; Racchi, M; Villetti, G1
Johnson, A1
Amari, G; Bartolucci, C; Bolzoni, PT; Delcanale, M; Ghidini, E; Lamba, D; Racchi, M; Siotto, M; Villetti, G1
Amoroso, S; Cassano, T; Castrignanò, S; Colaianna, M; Cuomo, V; Giustino, A; Steardo, L; Trabace, L1

Reviews

2 review(s) available for carbamates and ganstigmine

ArticleYear
Ganstigmine (CHF 2819).
    Drugs in R&D, 2002, Volume: 3, Issue:5

    Topics: Acetylcholine; Adult; Alkaloids; Alzheimer Disease; Animals; Carbamates; Cholinesterase Inhibitors; Clinical Trials, Phase II as Topic; Cognition Disorders; Dose-Response Relationship, Drug; Humans; Male; Rats

2002
Ganstigmine. Chiesi.
    Current opinion in investigational drugs (London, England : 2000), 2003, Volume: 4, Issue:7

    Topics: Alkaloids; Alzheimer Disease; Animals; Carbamates; Clinical Trials as Topic; Drugs, Investigational; Humans; Technology, Pharmaceutical

2003

Other Studies

6 other study(ies) available for carbamates and ganstigmine

ArticleYear
Phase I metabolism of ganstigmine. Rat, dog, monkey and human liver microsomal extracts investigated by liquid chromatography electrospray tandem mass spectrometry.
    Journal of mass spectrometry : JMS, 2001, Volume: 36, Issue:12

    Topics: Alkaloids; Alzheimer Disease; Animals; Carbamates; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Dogs; Humans; Hydroxylation; Macaca fascicularis; Male; Mass Spectrometry; Methylation; Microsomes, Liver; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Species Specificity

2001
The protective effect of ganstigmine against amyloid beta 25-35 neurotoxicity on chicken cortical neurons is independent from the cholinesterase inhibition.
    Neuroscience letters, 2003, May-08, Volume: 341, Issue:3

    Topics: Alkaloids; Amyloid beta-Peptides; Animals; Carbamates; Cell Survival; Cells, Cultured; Cerebral Cortex; Chick Embryo; Cholinesterase Inhibitors; Cholinesterases; Humans; Neurons; Neuroprotective Agents; Peptide Fragments

2003
Characterization of Ganstigmine metabolites in hepatocytes by low- and high-resolution mass spectrometry coupled with liquid chromatography.
    Rapid communications in mass spectrometry : RCM, 2003, Volume: 17, Issue:15

    Topics: Alkaloids; Animals; Carbamates; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Dogs; Glucuronides; Haplorhini; Hepatocytes; Humans; Infant; Male; Mass Spectrometry; Rats; Species Specificity

2003
Characterization of the effect of ganstigmine (CHF2819) on amyloid precursor protein metabolism in SH-SY5Y neuroblastoma cells.
    Journal of neural transmission (Vienna, Austria : 1996), 2003, Volume: 110, Issue:8

    Topics: Acetylcholine; Acetylcholinesterase; Alkaloids; Amyloid beta-Protein Precursor; Brain; Carbamates; Cell Line; Cholinesterase Inhibitors; Humans; Neuroblastoma; Neurons

2003
Structural determinants of Torpedo californica acetylcholinesterase inhibition by the novel and orally active carbamate based anti-alzheimer drug ganstigmine (CHF-2819).
    Journal of medicinal chemistry, 2006, Aug-24, Volume: 49, Issue:17

    Topics: Acetylcholinesterase; Administration, Oral; Alkaloids; Alzheimer Disease; Animals; Binding Sites; Brain; Carbamates; Cholinesterase Inhibitors; Crystallization; Crystallography, X-Ray; Drug Evaluation, Preclinical; Enzyme Activation; Male; Mice; Models, Molecular; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; Torpedo

2006
Neurochemical and neurobehavioral effects of ganstigmine (CHF2819), a novel acetylcholinesterase inhibitor, in rat prefrontal cortex: an in vivo study.
    Pharmacological research, 2007, Volume: 56, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Administration, Oral; Alkaloids; Analysis of Variance; Animals; Carbamates; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Dopamine; Exploratory Behavior; Extracellular Space; Homovanillic Acid; Male; Memory; Norepinephrine; Prefrontal Cortex; Rats; Rats, Wistar; Scopolamine; Serotonin

2007