carbamates and epothilone b

carbamates has been researched along with epothilone b in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's10 (83.33)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chakravarty, S; Danishefsky, SJ; He, L; Horwitz, SB; Inoue, T; Kuduk, SD; Lin, S; Ojima, I1
Arimoto, H; Danishefsky, SJ; Horwitz, SB; Kaufman, MD; Martello, LA; McDaid, HM; Meng, D; Pettus, TR; Regl, DL; Smith, AB; Yang, CP1
Adler, AJ; Crabtree, DV; Geng, X; Ojima, I1
Chen, JG; Horwitz, SB1
Bröker, LE; Ferreira, CG; Giaccone, G; Huisman, C; Kruyt, FA; Rodriguez, JA1
Braguer, D; Briand, C; Honore, S; Jordan, MA; Kamath, K; Wilson, L1
Bröker, LE; Giaccone, G; Huisman, C; Kruyt, FA; Rodriguez, JA; Span, SW1
Escuin, D; Giannakakou, P; Kline, ER1
Andreu, JM; Barasoain, I; Buey, RM; Calvo, E; Cerezo, G; Day, BW; Díaz, JF; Edler, MC; Hamel, E; López, JA; Matesanz, R; Pineda, O; Sorensen, EJ; Vanderwal, CD1
Balachandran, R; Curran, DP; Day, BW; Fukui, Y; Jung, WH; Madiraju, C; Montgomery, K; Raccor, BS; Shin, Y; Sikorski, RP; Vogt, A1
Altmann, KH; Gertsch, J; Meier, S; Müller, M1
Goldberg, GL; Horwitz, SB; Shahabi, S; Yang, CP1

Other Studies

12 other study(ies) available for carbamates and epothilone b

ArticleYear
A common pharmacophore for cytotoxic natural products that stabilize microtubules.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Apr-13, Volume: 96, Issue:8

    Topics: Alkaloids; Alkanes; Antineoplastic Agents, Phytogenic; Carbamates; Computer Graphics; Diterpenes; Epothilones; Epoxy Compounds; Lactones; Magnetic Resonance Spectroscopy; Microtubules; Models, Molecular; Molecular Conformation; Molecular Structure; Paclitaxel; Pyrones; Thiazoles

1999
Taxol and discodermolide represent a synergistic drug combination in human carcinoma cell lines.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:5

    Topics: Alkaloids; Alkanes; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Carbamates; Cell Count; Cell Division; Cell Line; Cytoskeleton; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Epothilones; Epoxy Compounds; Flow Cytometry; Humans; Lactones; Lung Neoplasms; Microtubules; Mitosis; Paclitaxel; Pyrones; Thiazoles; Tumor Cells, Cultured

2000
Tubulins in the primate retina: evidence that xanthophylls may be endogenous ligands for the paclitaxel-binding site.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:8

    Topics: Alkaloids; Alkanes; Animals; Antineoplastic Agents, Phytogenic; Binding Sites; Carbamates; Carotenoids; Diterpenes; Epothilones; Epoxy Compounds; Haplorhini; Humans; Lactones; Ligands; Lutein; Models, Molecular; Molecular Sequence Data; Paclitaxel; Pyrones; Retina; Thiazoles; Tubulin

2001
Differential mitotic responses to microtubule-stabilizing and -destabilizing drugs.
    Cancer research, 2002, Apr-01, Volume: 62, Issue:7

    Topics: Alkanes; Aneuploidy; Antineoplastic Agents; Carbamates; Carcinoma, Non-Small-Cell Lung; Epothilones; Humans; Lactones; Lung Neoplasms; Macrolides; Microtubules; Mitosis; Paclitaxel; Pyrones; Spindle Apparatus; Tumor Cells, Cultured

2002
Late activation of apoptotic pathways plays a negligible role in mediating the cytotoxic effects of discodermolide and epothilone B in non-small cell lung cancer cells.
    Cancer research, 2002, Jul-15, Volume: 62, Issue:14

    Topics: Alkanes; Antineoplastic Agents; Apoptosis; Carbamates; Carcinoma, Non-Small-Cell Lung; Caspase Inhibitors; Caspases; Epothilones; Humans; Inhibitory Concentration 50; Jurkat Cells; Lactones; Lung Neoplasms; Macrolides; Mitochondria; Pyrones; Receptors, Tumor Necrosis Factor; Tumor Cells, Cultured

2002
Suppression of microtubule dynamics by discodermolide by a novel mechanism is associated with mitotic arrest and inhibition of tumor cell proliferation.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:12

    Topics: Alkanes; Antineoplastic Agents; Carbamates; Cell Division; Cell Line, Tumor; Epothilones; Humans; Lactones; Microtubules; Mitosis; Paclitaxel; Pyrones

2003
Cathepsin B mediates caspase-independent cell death induced by microtubule stabilizing agents in non-small cell lung cancer cells.
    Cancer research, 2004, Jan-01, Volume: 64, Issue:1

    Topics: Alkanes; Antineoplastic Agents; Apoptosis; Base Sequence; Carbamates; Carcinoma, Non-Small-Cell Lung; Caspases; Cathepsin B; Cell Death; DNA Primers; Epothilones; Humans; Lactones; Lung Neoplasms; Lysosomes; Microscopy, Fluorescence; Microtubules; Paclitaxel; Pyrones; Transfection; Tumor Cells, Cultured

2004
Both microtubule-stabilizing and microtubule-destabilizing drugs inhibit hypoxia-inducible factor-1alpha accumulation and activity by disrupting microtubule function.
    Cancer research, 2005, Oct-01, Volume: 65, Issue:19

    Topics: 2-Methoxyestradiol; Alkaloids; Alkanes; Antineoplastic Agents; Carbamates; Cell Line, Tumor; Colchicine; Docetaxel; Down-Regulation; Epothilones; Estradiol; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactones; Microtubules; Pyrones; Taxoids; Vincristine

2005
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
    Nature chemical biology, 2007, Volume: 3, Issue:2

    Topics: Alkanes; Amino Acid Sequence; Asparagine; Binding Sites; Binding, Competitive; Carbamates; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Docetaxel; Epothilones; Humans; Inhibitory Concentration 50; Lactones; Mass Spectrometry; Microtubules; Models, Chemical; Models, Molecular; Molecular Sequence Data; Paclitaxel; Polycyclic Compounds; Protein Binding; Pyrones; Taxoids; Threonine; Tubulin; Tubulin Modulators

2007
Cell-based and biochemical structure-activity analyses of analogs of the microtubule stabilizer dictyostatin.
    Molecular pharmacology, 2008, Volume: 73, Issue:3

    Topics: Alkanes; Animals; Benzimidazoles; Binding Sites; Brain Chemistry; Carbamates; Carcinoma; Cattle; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Epothilones; Female; Fluorescein-5-isothiocyanate; Fluorescent Antibody Technique, Indirect; Fluorescent Dyes; G2 Phase; HeLa Cells; Histones; Humans; Kinetics; Lactones; Macrolides; Microtubules; Molecular Structure; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Protein Binding; Pyrones; Quantitative Structure-Activity Relationship; Radioligand Assay; Tubulin; Tubulin Modulators

2008
Differential effects of natural product microtubule stabilizers on microtubule assembly: single agent and combination studies with taxol, epothilone B, and discodermolide.
    Chembiochem : a European journal of chemical biology, 2009, Jan-05, Volume: 10, Issue:1

    Topics: Alkanes; Animals; Biological Products; Brain; Carbamates; Cell Proliferation; Drug Combinations; Drug Synergism; Epothilones; Humans; Lactones; Microscopy, Electron; Microtubules; Nephelometry and Turbidimetry; Paclitaxel; Protein Multimerization; Protein Structure, Quaternary; Pyrones; Swine; Tubulin; Tubulin Modulators

2009
Epothilone B enhances surface EpCAM expression in ovarian cancer Hey cells.
    Gynecologic oncology, 2010, Volume: 119, Issue:2

    Topics: Acetylation; Alkanes; Antigens, Neoplasm; Carbamates; Cell Adhesion Molecules; Cell Line, Tumor; Epithelial Cell Adhesion Molecule; Epothilones; Female; Humans; Hydroxamic Acids; Lactones; Ovarian Neoplasms; Paclitaxel; Pyrones; Tubulin; Tubulin Modulators; Vinblastine

2010