carbamates has been researched along with dirlotapide in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 10 (66.67) | 29.6817 |
| 2010's | 4 (26.67) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Barry, CJ; Bertinato, P; Blize, AE; Bronk, BS; Dirlam, JP; Haven, ML; Hickman, A; Jaynes, BH; Kolosko, NL; Li, J; Manion, TB; Miskell, C; Pillai, UA; Tibbitts, JS | 1 |
| Gossellin, J; Sunderland, SJ; Wren, JA | 1 |
| Bessire, AJ; Lynch, MP; Merritt, DA; Sams, JP; Vaz, AD | 1 |
| King, VL; Lynch, MP; Merritt, DA | 1 |
| Campbell, SL; Hickman, MA; King, VL; Wren, JA | 1 |
| Gossellin, J; Hickman, MA; Kerlin, RL; King, VL; Krautmann, MJ; Schmahai, TJ; Wren, JA | 1 |
| Gossellin, J; Peachey, S; Rowan, TG; Sherington, J; Sunderland, SJ | 1 |
| Boucher, JF; Kirk, CA; Sunderland, SJ; Wren, JA | 1 |
| Eagleson, JS; Gossellin, J; McKelvie, J; Rowan, TG; Sherington, J; Sunderland, SJ; Wren, JA | 1 |
| Campbell, SL; Eagleson, JS; Gossellin, J; King, VL; Ramudo, AA; Sunderland, SJ; Wren, JA | 1 |
| Bessire, AJ; Sharma, R; Vaz, AD; Walker, GS; Wang, WW | 1 |
| Bartlett, JA; Bertinato, P; Bessire, AJ; Cosgrove, J; Foley, PM; Manion, TB; Minich, ML; Ramos, B; Reese, MR; Robinson, RP; Schmahai, TJ; Swick, AG; Tess, DA; Vaz, A; Wolford, A | 1 |
| Bessire, AJ; Sun, H; Vaz, A | 1 |
| Ables, GP; Birtles, S; Blaner, WS; Buckett, LK; Ginsberg, HN; Goldberg, IJ; Hernandez-Ono, A; Huang, LS; Turnbull, AV; Vogel, S; Yang, KJ; Yu, S; Yuen, JJ | 1 |
| da Motta, KP; Domingues, NLC; Luchese, C; Santos, BF; Wilhelm, EA | 1 |
1 review(s) available for carbamates and dirlotapide
| Article | Year |
|---|---|
Dirlotapide: a review of its properties and role in the management of obesity in dogs.
Topics: Animals; Anti-Obesity Agents; Carbamates; Dog Diseases; Dogs; Indoles; Obesity | 2007 |
7 trial(s) available for carbamates and dirlotapide
| Article | Year |
|---|---|
Pharmacokinetics of dirlotapide in the dog.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Area Under Curve; Carbamates; Cross-Over Studies; Dogs; Female; Indoles; Injections, Intravenous; Male | 2007 |
Biologic activity of dirlotapide, a novel microsomal triglyceride transfer protein inhibitor, for weight loss in obese dogs.
Topics: Absorptiometry, Photon; Adipose Tissue; Administration, Oral; Animals; Anti-Obesity Agents; Body Composition; Body Weight; Carbamates; Carrier Proteins; Dog Diseases; Dogs; Eating; Female; Indoles; Male; Obesity; Treatment Outcome | 2007 |
The safety of dirlotapide in dogs.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Carbamates; Dog Diseases; Dogs; Female; Indoles; Male; Obesity; Safety | 2007 |
Evaluation of dirlotapide for sustained weight loss in overweight Labrador retrievers.
Topics: Absorptiometry, Photon; Administration, Oral; Animals; Anti-Obesity Agents; Carbamates; Dog Diseases; Dogs; Eating; Female; Indoles; Male; Pedigree; Treatment Outcome; Weight Loss | 2007 |
Influence of dirlotapide, a microsomal triglyceride transfer protein inhibitor, on the digestibility of a dry expanded diet in adult dogs.
Topics: Administration, Oral; Animal Feed; Animals; Anti-Obesity Agents; Carbamates; Carrier Proteins; Diet; Digestion; Dog Diseases; Dogs; Double-Blind Method; Female; Indoles; Male; Obesity; Prospective Studies; Treatment Outcome | 2007 |
An evaluation of dirlotapide to reduce body weight of client-owned dogs in two placebo-controlled clinical studies in Europe.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Body Weight; Carbamates; Dog Diseases; Dogs; Europe; Female; Indoles; Male; Ownership; Pedigree; Treatment Outcome; Weight Loss | 2007 |
Efficacy and safety of dirlotapide in the management of obese dogs evaluated in two placebo-controlled, masked clinical studies in North America.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Carbamates; Dog Diseases; Dogs; Female; Indoles; Male; North America; Obesity; Treatment Outcome | 2007 |
7 other study(ies) available for carbamates and dirlotapide
| Article | Year |
|---|---|
In vitro and in vivo profile of 5-[(4'-trifluoromethyl-biphenyl-2-carbonyl)-amino]-1H-indole-2-carboxylic acid benzylmethyl carbamoylamide (dirlotapide), a novel potent MTP inhibitor for obesity.
Topics: Animals; Carbamates; Carboxylic Acids; Carrier Proteins; Chemistry, Pharmaceutical; Dogs; Drug Design; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Indoles; Inhibitory Concentration 50; Models, Chemical; Molecular Conformation; Obesity; Rats | 2007 |
Absorption, distribution, metabolism, and excretion of dirlotapide in the dog.
Topics: Administration, Oral; Animals; Anti-Obesity Agents; Bile; Carbamates; Carbon Radioisotopes; Dogs; Female; Indoles; Male; Tissue Distribution | 2007 |
The use of 18O-exchange and base-catalyzed N-dealkylation with liquid chromatography/tandem mass spectrometry to identify carbinolamide metabolites.
Topics: Animals; Carbamates; Catalysis; Chromatography, Liquid; Dealkylation; Female; Indoles; Male; Molecular Structure; Oxygen Isotopes; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry | 2010 |
Discovery of microsomal triglyceride transfer protein (MTP) inhibitors with potential for decreased active metabolite load compared to dirlotapide.
Topics: Aminoquinolines; Animals; Benzamides; Carbamates; Carrier Proteins; Dogs; Drug Evaluation, Preclinical; Humans; Indoles; Microsomes, Liver; Rats; Triglycerides | 2011 |
Dirlotapide as a model substrate to refine structure-based drug design strategies on CYP3A4-catalyzed metabolism.
Topics: Carbamates; Catalysis; Catalytic Domain; Chemistry, Pharmaceutical; Computer Simulation; Crystallization; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Drug Design; Indoles; Ligands; Mass Spectrometry; Microsomes, Liver; Models, Chemical; Models, Molecular; Molecular Conformation; Protein Conformation; Temperature | 2012 |
Intestinal DGAT1 deficiency reduces postprandial triglyceride and retinyl ester excursions by inhibiting chylomicron secretion and delaying gastric emptying.
Topics: Animals; Carbamates; Carrier Proteins; Chylomicrons; Diacylglycerol O-Acyltransferase; Gastric Emptying; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Indoles; Male; Mice; Mice, Mutant Strains; Peptide Fragments; Postprandial Period; Receptors, Glucagon; Retinoids; Triglycerides | 2012 |
Target enzymes in oxaliplatin-induced peripheral neuropathy in Swiss mice: A new acetylcholinesterase inhibitor as therapeutic strategy.
Topics: Adenosine Triphosphatases; Analgesics; Animals; Anxiety; Benzoates; Carbamates; Cerebral Cortex; Cholinesterase Inhibitors; Cognitive Dysfunction; Disease Models, Animal; Female; Hippocampus; Indoles; Male; Mice; Oxaliplatin; Oxidative Stress; Peripheral Nervous System Diseases; Spinal Cord; Thiadiazoles; Thiazoles | 2022 |