carbamates has been researched along with carbostyril in 62 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (4.84) | 29.6817 |
| 2010's | 58 (93.55) | 24.3611 |
| 2020's | 1 (1.61) | 2.80 |
| Authors | Studies |
|---|---|
| Doi, T; Nagabukuro, H | 1 |
| Farina, V; Haddad, N; Tan, J | 1 |
| Conway, CM; Dalterio, RA; Degnan, AP; Dubowchik, GM; Macci, R; Macor, JE; Mercer, SE; Schartman, R; Xu, C | 1 |
| Behera, P; Sahoo, PK | 1 |
| Baldwin, R; Bartfai, T; Chang, J; Liu, T; Lu, X; Roberts, E; Sanchez-Alavez, M; Wasterlain, CG; Wu, S; Xia, F | 1 |
| Hughes, AD; Klein, U; Mammen, M; Smith, JA; Steinfeld, T | 1 |
| Chuck, SL; Cohen, C; DeJesus, E; Elion, R; Kearney, BP; Liu, HC; Ramanathan, S; Rashbaum, B; Ruane, P; Shamblaw, D; Warren, DR; Yale, K | 1 |
| Lampiris, HW | 1 |
| Belavic, JM | 2 |
| Marchand, C | 1 |
| Cheng, AK; DeJesus, E; Gathe, J; Henry, K; Kearney, BP; Molina, JM; Ramanathan, S; Rockstroh, JK; Szwarcberg, J; Wei, X; White, K; Yale, K | 1 |
| Cheng, AK; Cohen, C; DeJesus, E; Gallant, JE; Kearney, BP; Liu, HC; Mills, A; Quirk, E; Sax, PE; Szwarcberg, J; White, K; Wohl, D; Yale, K; Zhong, L; Zolopa, A | 1 |
| Hegde, SS; Mammen, M; Martin, WJ; McNamara, A; Pulido-Rios, MT; Stangeland, E; Steinfeld, T | 1 |
| Debyser, Z; Schrijvers, R | 2 |
| Pommer, P | 1 |
| Maxmen, A | 1 |
| Klibanov, OM; Olin, JL; Spooner, LM | 1 |
| Hussar, DA; Martinez, LN | 1 |
| Breeze, S | 1 |
| Morrow, T | 1 |
| Temesgen, Z | 1 |
| Hussar, DA | 2 |
| Abram, M; Cheng, AK; DeJesus, E; Fordyce, MW; Gathe, J; Henry, K; Molina, JM; Plummer, A; Ramanathan, S; Rockstroh, JK; Szwarcberg, J; Wei, X | 1 |
| Cheng, AK; Cohen, C; DeJesus, E; Gallant, JE; Liu, HC; Mills, A; Plummer, A; Rhee, MS; Sax, PE; Szwarcberg, J; White, KL; Wohl, D; Zolopa, A | 1 |
| Baggen, S; Chan, R; Locantore, N; Ludwig-Sengpiel, A; Riley, JH; Wielders, PL | 1 |
| Ambery, C; Norris, V | 2 |
| Ambery, C; Bateman, ED; Kornmann, O; Norris, V | 1 |
| Bruce, RD; Custodio, JM; Friedland, GH; Kearney, BP; Ramanathan, S; Rhee, MS; Wei, LX; Winkle, P | 1 |
| Cheng, A; Kearney, BP; Koziara, J; Mathias, A; Ramanathan, S; Shen, G; Wei, X | 1 |
| Aldir, I; Horta, A; Serrado, M | 1 |
| Bruce, RD; Custodio, JM; Friedland, GH; Kearney, BP; Ramanathan, S; Rhee, MS; Wei, X; Winkle, P | 1 |
| Cazzola, M; Lopez-Campos, JL; Puente-Maestu, L | 1 |
| Perry, CM | 1 |
| Andrews, J; Cheng, A; Custodio, JM; Hao, J; Kearney, BP; Lepist, EI; Ling, KH; Ramanathan, S; Ray, AS; Wang, H | 1 |
| Ikeda, A; Irie, S; Ishikawa, T; Kimura, M; Matsuki, S; Nishino, N; Shiomi, M | 1 |
| Hsiao, CB; Ma, Q; Sawyer, JR | 1 |
| Ayala-Sims, VA; Fulco, PP | 1 |
| Antela, A; Domingo, P; Garner, W; Girard, PM; Guyer, B; Henry, K; Markowitz, M; Mills, A; Nguyen, T; Piontkowsky, D; Pozniak, A; Stellbrink, HJ; White, K | 1 |
| Arribas, JR; Di Perri, G; Ebrahimi, R; Gathe, J; Nguyen, T; Pialoux, G; Piontkowsky, D; Reynes, J; Tebas, P; White, K | 1 |
| Bruzzone, B; Di Biagio, A; Gustinetti, G; Prinapori, R; Sticchi, L; Taramasso, L; Viscoli, C | 1 |
| Chen, Y; Hegde, SS; Hughes, AD; Jasper, JR; Lee, TW; Mammen, M; Martin, WJ; McNamara, A; Pulido-Rios, MT; Steinfeld, T | 1 |
| Dai, CG; Du, XJ; Liu, XL; Song, QH | 1 |
| Abram, ME; Andrade-Villanueva, JF; Beraud, C; Cheng, AK; Fisher, M; Graham, H; Liu, Y; Post, FA; Rhee, MS; Szwarcberg, J; Winston, J | 1 |
| Fisher, M; Raffe, S | 1 |
| Chen, Y; Hegde, SS; Hughes, AD; Jasper, JR; Jaw-Tsai, S; Lee, TW; Mammen, M; McNamara, A; Pulido-Rios, MT; Steinfeld, T | 1 |
| Harirforoosh, S; Moorman, JP; Murrell, DE | 1 |
| Baeten, JM; Wyatt, C | 1 |
| Andrade-Villanueva, J; Callebaut, C; Cao, H; Cheng, AK; Crofoot, G; Custodio, JM; DeJesus, E; Fordyce, MW; Koenig, E; Martin, H; McCallister, S; Molina, JM; Oka, S; Plummer, A; Podzamczer, D; Post, F; Pozniak, A; Saag, M; Sax, PE; Thompson, M; Trottier, B; Wohl, D; Yin, MT; Zhong, L | 1 |
| Stone, L | 1 |
| Ambery, CL; Chan, R; Ludwig-Sengpiel, A; Riley, JH; Wielders, P | 1 |
| Ambery, C; Norris, V; Riley, T | 1 |
| Ambery, C; Daley-Yates, P; Riddell, K | 1 |
| Ambery, C; Daley-Yates, P; Fuller, T; Georgiou, A; Puri, A; Ramsay, D; Young, G | 1 |
| Baidoo, C; Castro-Santamaria, R; Crawford, C; Crim, C; Emmett, A; Gotfried, M; Spangenthal, S; Watkins, M | 1 |
9 review(s) available for carbamates and carbostyril
| Article | Year |
|---|---|
Elvitegravir: a once-daily, boosted, HIV-1 integrase inhibitor.
Topics: Adenine; Carbamates; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Deoxycytidine; Drug Combinations; Drug Interactions; Drug Resistance, Viral; Drug-Related Side Effects and Adverse Reactions; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; HIV Integrase Inhibitors; HIV-1; Humans; Organophosphonates; Quinolones; Randomized Controlled Trials as Topic; Thiazoles | 2012 |
Combinational therapies for HIV: a focus on EVG/COBI/FTC/TDF.
Topics: Adenine; Anti-HIV Agents; Carbamates; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Cobicistat; Deoxycytidine; Drug Combinations; Drug Resistance, Multiple, Viral; Emtricitabine; HIV Infections; Humans; Organophosphonates; Quinolones; Tenofovir; Thiazoles | 2012 |
Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate single tablet for HIV-1 infection treatment.
Topics: Adenine; Anti-HIV Agents; Carbamates; Clinical Trials, Phase III as Topic; Deoxycytidine; Drug Combinations; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; HIV Integrase Inhibitors; Humans; Organophosphonates; Quinolones; Tablets; Thiazoles; Viral Load | 2012 |
Cobicistat-boosted elvitegravir-based fixed-dose combination antiretroviral therapy for HIV infection.
Topics: Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Carbamates; Cobicistat; Drug Approval; Drug Combinations; Drug Interactions; Drug Resistance, Viral; HIV Infections; HIV Integrase Inhibitors; Humans; Patient Safety; Quinolones; Thiazoles | 2012 |
Single-tablet regimens in HIV: does it really make a difference?
Topics: Adenine; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Emtricitabine; HIV Infections; HIV-1; Humans; Nitriles; Organophosphonates; Pyrimidines; Quinolones; Reverse Transcriptase Inhibitors; Rilpivirine; Tablets; Tenofovir; Thiazoles | 2014 |
Elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate single-tablet regimen (Stribild®): a review of its use in the management of HIV-1 infection in adults.
Topics: Adenine; Anti-HIV Agents; Carbamates; Deoxycytidine; Drug Combinations; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Quinolones; Tablets; Thiazoles | 2014 |
Which patients have greatest need for elvitegravir/cobicistat/ emtricitabine/tenofovirDF-based therapy?
Topics: Adenine; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Drug Combinations; Emtricitabine; HIV Infections; HIV-1; Humans; Patents as Topic; Phosphorous Acids; Quinolones; Thiazoles | 2014 |
The pharmacokinetics, pharmacodynamics and clinical efficacy of elvitegravir + cobicistat + emtricitabine + tenofovir combination therapy for the treatment of HIV.
Topics: Adenine; Adult; Anti-HIV Agents; Carbamates; Deoxycytidine; Drug Approval; Drug Combinations; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; European Union; HIV Infections; HIV-1; Humans; Organophosphonates; Quinolones; Tablets; Thiazoles | 2015 |
Stribild: a review of component characteristics and combination drug efficacy.
Topics: Adenine; Anti-HIV Agents; Carbamates; Deoxycytidine; Drug Combinations; Drug Synergism; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Organophosphonates; Quinolones; Thiazoles | 2015 |
20 trial(s) available for carbamates and carbostyril
| Article | Year |
|---|---|
Randomized, phase 2 evaluation of two single-tablet regimens elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate versus efavirenz/emtricitabine/tenofovir disoproxil fumarate for the initial treatment of HIV infection.
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Cobicistat; Cyclopropanes; Deoxycytidine; Drug Combinations; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Patient Compliance; Patient Selection; Quinolones; Tenofovir; Thiazoles; Treatment Outcome | 2011 |
Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir disoproxil fumarate versus ritonavir-boosted atazanavir plus co-formulated emtricitabine and tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: a randomised, double-
Topics: Adenine; Adult; Anti-HIV Agents; Atazanavir Sulfate; Carbamates; Cobicistat; Deoxycytidine; Double-Blind Method; Drug Combinations; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Oligopeptides; Organophosphonates; Pyridines; Quinolones; Ritonavir; Tenofovir; Thiazoles | 2012 |
Co-formulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus co-formulated efavirenz, emtricitabine, and tenofovir for initial treatment of HIV-1 infection: a randomised, double-blind, phase 3 trial, analysis of results after 48 weeks.
Topics: Adenine; Adult; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cobicistat; Cyclopropanes; Deoxycytidine; Double-Blind Method; Drug Combinations; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Male; Middle Aged; Organophosphonates; Quinolones; Tenofovir; Thiazoles | 2012 |
A randomized, double-blind comparison of coformulated elvitegravir/cobicistat/emtricitabine/tenofovir DF vs ritonavir-boosted atazanavir plus coformulated emtricitabine and tenofovir DF for initial treatment of HIV-1 infection: analysis of week 96 results
Topics: Adenine; Adult; Alanine Transaminase; Anti-HIV Agents; Aspartate Aminotransferases; Atazanavir Sulfate; Bilirubin; Bone Density; Carbamates; Cobicistat; Confidence Intervals; Creatinine; Deoxycytidine; Double-Blind Method; Drug Combinations; Emtricitabine; Female; HIV Infections; HIV-1; Humans; Male; Oligopeptides; Organophosphonates; Pyridines; Quinolones; Ritonavir; RNA, Viral; Tenofovir; Thiazoles; Triglycerides | 2013 |
A randomized double-blind comparison of coformulated elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate versus efavirenz/emtricitabine/tenofovir disoproxil fumarate for initial treatment of HIV-1 infection: analysis of week 96 results.
Topics: Adenine; Adult; Anti-HIV Agents; Carbamates; Creatinine; Deoxycytidine; Double-Blind Method; Drug Combinations; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Female; HIV Infections; HIV-1; Humans; Male; Organophosphonates; Oxazines; Quinolones; RNA, Viral; Thiazoles; Treatment Outcome; Young Adult | 2013 |
A new class of bronchodilator improves lung function in COPD: a trial with GSK961081.
Topics: Aged; Albuterol; Bronchodilator Agents; Carbamates; Double-Blind Method; Drug Administration Schedule; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Muscarinic Antagonists; Patient Safety; Pulmonary Disease, Chronic Obstructive; Quinolones; Salmeterol Xinafoate; Smoking; Spirometry; Treatment Outcome | 2013 |
Bronchodilation and safety of supratherapeutic doses of salbutamol or ipratropium bromide added to single dose GSK961081 in patients with moderate to severe COPD.
Topics: Aged; Albuterol; Bronchodilator Agents; Carbamates; Cross-Over Studies; Delayed-Action Preparations; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Ipratropium; Male; Middle Aged; Pulmonary Disease, Chronic Obstructive; Quinolones; Severity of Illness Index; Time Factors; Treatment Outcome | 2013 |
Pharmacodynamics of GSK961081, a bi-functional molecule, in patients with COPD.
Topics: Adrenergic beta-2 Receptor Agonists; Adult; Aged; Albuterol; Bronchodilator Agents; Carbamates; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones; Salmeterol Xinafoate; Scopolamine Derivatives; Time Factors; Tiotropium Bromide; Treatment Outcome | 2013 |
Pharmacokinetics of once-daily boosted elvitegravir when administered in combination with acid-reducing agents.
Topics: Adolescent; Adult; Antacids; Anti-HIV Agents; Area Under Curve; Carbamates; Cobicistat; Cross-Over Studies; Drug Administration Schedule; Drug Interactions; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinolones; Thiazoles | 2013 |
Pharmacokinetics of cobicistat boosted-elvitegravir administered in combination with rosuvastatin.
Topics: Adult; Animals; Anti-HIV Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Carbamates; CHO Cells; Cobicistat; Cricetulus; Dogs; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver-Specific Organic Anion Transporter 1; Madin Darby Canine Kidney Cells; Male; Neoplasm Proteins; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Pyrimidines; Quinolones; Rosuvastatin Calcium; Solute Carrier Organic Anion Transporter Family Member 1B3; Sulfonamides; Thiazoles | 2014 |
Effects of a protein-rich drink or a standard meal on the pharmacokinetics of elvitegravir, cobicistat, emtricitabine and tenofovir in healthy Japanese male subjects: a randomized, three-way crossover study.
Topics: Adenine; Adult; Anti-HIV Agents; Asian People; Beverages; Carbamates; Cobicistat; Cross-Over Studies; Deoxycytidine; Dietary Proteins; Drug Combinations; Emtricitabine; Food-Drug Interactions; Humans; Male; Middle Aged; Organophosphonates; Quinolones; Tenofovir; Thiazoles; Young Adult | 2014 |
Switching to coformulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus continuation of non-nucleoside reverse transcriptase inhibitor with emtricitabine and tenofovir in virologically suppressed adults with HIV (STRATEGY-NNRTI): 48 week r
Topics: Adenine; Adult; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Quinolones; Reverse Transcriptase Inhibitors; Tenofovir; Thiazoles; Viral Load | 2014 |
Simplification to coformulated elvitegravir, cobicistat, emtricitabine, and tenofovir versus continuation of ritonavir-boosted protease inhibitor with emtricitabine and tenofovir in adults with virologically suppressed HIV (STRATEGY-PI): 48 week results o
Topics: Adenine; Adult; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; Female; HIV; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Protease Inhibitors; Quinolones; Ritonavir; Tenofovir; Thiazoles; Viral Load | 2014 |
Use of propranolol blockade to explore the pharmacology of GSK961081, a bi-functional bronchodilator, in healthy volunteers: results from two randomized trials.
Topics: Administration, Inhalation; Administration, Oral; Adolescent; Adrenergic beta-2 Receptor Agonists; Adult; Bronchodilator Agents; Carbamates; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Male; Metered Dose Inhalers; Middle Aged; Muscarinic Antagonists; Propranolol; Quinolones; Time Factors; Young Adult | 2014 |
Tenofovir alafenamide versus tenofovir disoproxil fumarate, coformulated with elvitegravir, cobicistat, and emtricitabine, for initial treatment of HIV-1 infection: two randomised, double-blind, phase 3, non-inferiority trials.
Topics: Adenine; Adult; Alanine; Anti-HIV Agents; Arthralgia; Bone Density; Carbamates; CD4 Lymphocyte Count; Cobicistat; Deoxycytidine; Double-Blind Method; Drug Combinations; Emtricitabine; Female; Headache; HIV Infections; Humans; Kidney; Male; Nausea; Organophosphonates; Quinolones; Respiration Disorders; Sleep Initiation and Maintenance Disorders; Tenofovir; Thiazoles; Treatment Outcome; Viral Load | 2015 |
Population Pharmacokinetics and Pharmacodynamics of GSK961081 (Batefenterol), a Muscarinic Antagonist and β2-Agonist, in Moderate-to-Severe COPD Patients: Substudy of a Randomized Trial.
Topics: Adrenergic beta-2 Receptor Agonists; Adult; Aged; Carbamates; Dose-Response Relationship, Drug; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones | 2015 |
Pharmacokinetics and pharmacodynamics of GSK961081, a novel inhaled muscarinic antagonist β2 -agonist, and fluticasone propionate administered alone, concurrently and as a combination blend formulation in healthy volunteers.
Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Area Under Curve; Biomarkers; Carbamates; Cross-Over Studies; Double-Blind Method; Drug Combinations; Drug Compounding; Drug Therapy, Combination; Dry Powder Inhalers; Female; Fluticasone; Healthy Volunteers; Humans; Hydrocortisone; Male; Muscarinic Antagonists; Quinolones | 2014 |
Open-Label, Randomized, 6-Way Crossover, Single-Dose Study to Determine the Pharmacokinetics of Batefenterol (GSK961081) and Fluticasone Furoate When Administered Alone or in Combination.
Topics: Administration, Inhalation; Adolescent; Adult; Androstadienes; Area Under Curve; Bronchodilator Agents; Carbamates; Cross-Over Studies; Drug Combinations; Dry Powder Inhalers; Female; Humans; Male; Middle Aged; Quinolones; Young Adult | 2016 |
Open-Label, Crossover Study to Determine the Pharmacokinetics of Fluticasone Furoate and Batefenterol When Administered Alone, in Combination, or Concurrently.
Topics: Adult; Androstadienes; Area Under Curve; Carbamates; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Male; Middle Aged; Quinolones; Young Adult | 2019 |
A randomized, controlled, repeat-dose study of batefenterol/fluticasone furoate compared with placebo in the treatment of COPD.
Topics: Administration, Inhalation; Aged; Androstadienes; Carbamates; Double-Blind Method; Drug Combinations; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Nebulizers and Vaporizers; Pulmonary Disease, Chronic Obstructive; Quinolones; Treatment Outcome | 2020 |
33 other study(ies) available for carbamates and carbostyril
| Article | Year |
|---|---|
Differential effects of TAK-802, a selective acetylcholinesterase inhibitor, and carbamate acetylcholinesterase inhibitors on contraction of the detrusor smooth muscle of the guinea pig.
Topics: Acetylcholinesterase; Animals; Carbamates; Cholinesterase Inhibitors; Guinea Pigs; Isometric Contraction; Male; Muscle, Smooth; Nicotine; Nicotinic Agonists; Pyrroles; Quinolones; Tissue Culture Techniques; Urinary Bladder | 2005 |
Convergent synthesis of the quinolone substructure of BILN 2061 via carbonylative Sonogashira coupling/cyclization.
Topics: Alkynes; Carbamates; Catalysis; Cyclization; Hydrocarbons, Iodinated; Macrocyclic Compounds; Molecular Structure; Palladium; Quinolines; Quinolones; Stereoisomerism; Thiazoles | 2006 |
Carbamates as potent calcitonin gene-related peptide antagonists with improved solution stability.
Topics: Calcitonin Gene-Related Peptide Receptor Antagonists; Carbamates; Drug Stability; Humans; Indazoles; Migraine Disorders; Quinazolinones; Quinolones; Receptors, Calcitonin Gene-Related Peptide | 2009 |
Synthesis and biological screening of some novel amidocarbamate derivatives of ketoprofen.
Topics: Antiviral Agents; Biphenyl Compounds; Carbamates; Cell Line; Cytostatic Agents; DNA Viruses; Drug Evaluation, Preclinical; Free Radical Scavengers; Glycine max; Inhibitory Concentration 50; Linoleic Acid; Lipid Peroxidation; Lipoxygenase; Lipoxygenase Inhibitors; Picrates; Quinolones; RNA Viruses | 2010 |
GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models.
Topics: Allosteric Regulation; Animals; Anticonvulsants; Carbamates; Cell Line; Dipeptides; Disease Models, Animal; Electroshock; Humans; Male; Mice; Mice, Inbred C57BL; Pilocarpine; Quinolones; Rats; Rats, Wistar; Receptor, Galanin, Type 1; Receptor, Galanin, Type 2; Recombinant Proteins; Seizures; Signal Transduction; Status Epilepticus | 2010 |
THRX-198321 is a bifunctional muscarinic receptor antagonist and beta2-adrenoceptor agonist (MABA) that binds in a bimodal and multivalent manner.
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Binding Sites; Binding, Competitive; Carbamates; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Guanosine 5'-O-(3-Thiotriphosphate); Inositol Phosphates; Muscarinic Agonists; Pharmacokinetics; Quinolones; Radioligand Assay | 2011 |
Annual drug update: 2011 in review.
Topics: Abatacept; Aminoglycosides; Carbamates; Drug Approval; Fentanyl; Fidaxomicin; Humans; Immunoconjugates; Indans; Linagliptin; Phenylenediamines; Proline; Purines; Quinazolines; Quinolones; United States; United States Food and Drug Administration | 2012 |
The elvitegravir Quad pill: the first once-daily dual-target anti-HIV tablet.
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Carbamates; Clinical Trials as Topic; Deoxycytidine; Drug Administration Schedule; Drug Combinations; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Organophosphonates; Quinolones; Tablets; Thiazoles | 2012 |
Preclinical efficacy of THRX-200495, a dual pharmacology muscarinic receptor antagonist and β(2)-adrenoceptor agonist (MABA).
Topics: Adrenergic beta-2 Receptor Agonists; Animals; Bronchi; Carbamates; Guinea Pigs; Histamine Release; Male; Methacholine Chloride; Muscarinic Antagonists; Quinolones | 2012 |
[A single tablet against HIV: new combination preparation improves therapy].
Topics: Adenine; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Atazanavir Sulfate; Benzoxazines; Carbamates; CD4 Lymphocyte Count; Clinical Trials, Phase III as Topic; Cobicistat; Cyclopropanes; Deoxycytidine; Double-Blind Method; Drug Combinations; Drug Resistance, Viral; Emtricitabine; Glomerular Filtration Rate; HIV Infections; Humans; Oligopeptides; Organophosphonates; Pyridines; Quinolones; Randomized Controlled Trials as Topic; Ritonavir; Tenofovir; Thiazoles; Viral Load | 2012 |
Generic HIV drugs will widen US treatment net.
Topics: Adenine; Anti-HIV Agents; Budgets; Carbamates; Cost-Benefit Analysis; Deoxycytidine; Drug Combinations; Drug Costs; Drugs, Generic; Efavirenz, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Federal Government; Humans; Organophosphonates; Oxazines; Patents as Topic; Quinolones; Thiazoles; United States | 2012 |
FDA approves new 4-drug once-a-day HIV treatment.
Topics: Adenine; Carbamates; Cobicistat; Deoxycytidine; Drug Administration Schedule; Drug Approval; Drug Combinations; Emtricitabine; HIV Infections; Humans; Organophosphonates; Quinolones; Tenofovir; Thiazoles; United States; United States Food and Drug Administration | 2012 |
A 4-drug combination (Stribild) for HIV.
Topics: Adenine; Anti-HIV Agents; Carbamates; Clinical Trials as Topic; Cobicistat; Deoxycytidine; Double-Blind Method; Drug Approval; Drug Combinations; Drug Interactions; Drug Resistance, Multiple, Viral; Emtricitabine; HIV; HIV Infections; Humans; Organophosphonates; Quinolones; Randomized Controlled Trials as Topic; Tenofovir; Thiazoles; United States; United States Food and Drug Administration | 2012 |
Elvitegravir/cobicistat, mirabegron, and linaclotide.
Topics: Acetanilides; Adenine; Anti-Retroviral Agents; Carbamates; Constipation; Deoxycytidine; Drug Combinations; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; HIV-1; Humans; Organophosphonates; Peptides; Quinolones; Thiazoles; Urinary Bladder, Overactive | 2012 |
Novel HIV-1 treatment Stribild™ gains regulatory approval.
Topics: Adenine; Anti-HIV Agents; Carbamates; Deoxycytidine; Drug Approval; Drug Combinations; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV; HIV Infections; Humans; Organophosphonates; Quinolones; Thiazoles | 2012 |
Improved adherence expected with new HIV combo treatment.
Topics: Adenine; Aged; Aged, 80 and over; Anti-HIV Agents; Carbamates; Deoxycytidine; Drug Combinations; Drug Labeling; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; HIV Infections; Humans; Medication Adherence; Middle Aged; Organophosphonates; Quinolones; Randomized Controlled Trials as Topic; Thiazoles; United States | 2012 |
Drug updates and approvals: 2012 in review.
Topics: Acetanilides; Adenine; Antibodies, Monoclonal, Humanized; Benzazepines; Carbamates; Cobicistat; Deoxycytidine; Drug Approval; Drug Combinations; Elvitegravir, Cobicistat, Emtricitabine, Tenofovir Disoproxil Fumarate Drug Combination; Emtricitabine; Fatty Alcohols; Humans; Mifepristone; Nicotinic Acids; Nurse Practitioners; Organophosphonates; Phosphatidylglycerols; Prednisone; Proteins; Pyrimidines; Quinolones; Ranibizumab; Tenofovir; Thiazoles; United States; United States Food and Drug Administration | 2013 |
New drugs 2013, Part I.
Topics: Aminophenols; Anilides; Antibodies, Monoclonal, Humanized; Axitinib; Benzodiazepines; Carbamates; Clobazam; Diterpenes; Drug Approval; gamma-Glutamyl Hydrolase; Glucosylceramidase; Humans; Imidazoles; Indans; Indazoles; Peptides; Phenylenediamines; Prostaglandins F; Pyridines; Quinolones | 2013 |
The pharmacokinetic and pharmacodynamic interactions between buprenorphine/naloxone and elvitegravir/cobicistat in subjects receiving chronic buprenorphine/naloxone treatment.
Topics: Adult; Anti-Retroviral Agents; Area Under Curve; Buprenorphine; Carbamates; Cobicistat; Drug Interactions; Female; HIV Infections; HIV Seronegativity; Humans; Male; Middle Aged; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Quinolones; Thiazoles | 2013 |
[ First integrase inhibitor based single tablet regimen].
Topics: Adenine; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Carbamates; Cobicistat; Deoxycytidine; Drug Approval; Drug Combinations; Emtricitabine; HIV Infections; HIV Integrase Inhibitors; Humans; Organophosphonates; Quinolones; Tenofovir; Thiazoles; Treatment Outcome | 2013 |
Investigation of the interactions between methadone and elvitegravir-cobicistat in subjects receiving chronic methadone maintenance.
Topics: Adult; Anti-HIV Agents; Area Under Curve; Carbamates; Cobicistat; Drug Interactions; Female; Humans; Male; Methadone; Middle Aged; Narcotics; Opiate Substitution Treatment; Opioid-Related Disorders; Quinolones; Thiazoles | 2013 |
The MABA approach: a new option to improve bronchodilator therapy.
Topics: Bronchodilator Agents; Carbamates; Female; Humans; Male; Pulmonary Disease, Chronic Obstructive; Quinolones | 2013 |
Cobicistat + elvitegravir + emtricitabine + tenofovir. Two new drugs, but no progress.
Topics: Acquired Immunodeficiency Syndrome; Adenine; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Drug Therapy, Combination; Emtricitabine; HIV-1; Humans; Organophosphonates; Quinolones; Tenofovir; Thiazoles | 2013 |
Single-tablet, once-daily treatment regimens for HIV.
Topics: Adenine; Alkynes; Anti-HIV Agents; Benzoxazines; Carbamates; Cobicistat; Cyclopropanes; Cytochrome P-450 CYP3A Inhibitors; Deoxycytidine; Drug Combinations; Emtricitabine; HIV Infections; HIV Integrase Inhibitors; HIV Reverse Transcriptase; Humans; Nitriles; Organophosphonates; Pyrimidines; Quinolones; Reverse Transcriptase Inhibitors; Rilpivirine; Tenofovir; Thiazoles | 2014 |
Sustained virological response after taking crushed elvitegravir-cobicistat-emtricitabine-tenofovir tablets.
Topics: Adenine; Adult; Antiretroviral Therapy, Highly Active; Carbamates; Cobicistat; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Organophosphonates; Powders; Quinolones; Tablets; Tenofovir; Thiazoles; Viral Load | 2014 |
Switching STRATEGIES in HIV treatment.
Topics: Adenine; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Emtricitabine; Female; HIV; HIV Infections; Humans; Male; Organophosphonates; Protease Inhibitors; Quinolones; Reverse Transcriptase Inhibitors; Ritonavir; Tenofovir; Thiazoles | 2014 |
Pharmacologic characterization of GSK-961081 (TD-5959), a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.
Topics: Adrenergic beta-2 Receptor Antagonists; Albuterol; Animals; Bronchodilator Agents; Carbamates; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Drug Evaluation, Preclinical; Guinea Pigs; HEK293 Cells; Humans; Lung; Muscarinic Antagonists; Muscle Relaxation; Muscle, Smooth; Protein Binding; Quinolones; Receptors, Adrenergic, beta; Receptors, Muscarinic; Salmeterol Xinafoate; Scopolamine Derivatives; Tiotropium Bromide; Tissue Distribution; Trachea | 2014 |
Ratiometric two-photon fluorescent probes for mitochondrial hydrogen sulfide in living cells.
Topics: 1-Naphthylamine; Benzyl Compounds; Carbamates; Fluorescent Dyes; Humans; Hydrogen Sulfide; Mitochondria; Naphthalimides; Optical Imaging; Photons; Quinolones | 2014 |
Elvitegravir/cobicistat/emtricitabine/tenofovir DF in HIV-infected patients with mild-to-moderate renal impairment.
Topics: Adenine; Adult; Anti-HIV Agents; Carbamates; Cobicistat; Cohort Studies; Deoxycytidine; Emtricitabine; Female; HIV Infections; Humans; Male; Middle Aged; Organophosphonates; Quinolones; Renal Insufficiency; Tenofovir; Thiazoles; Treatment Outcome | 2015 |
Discovery of (R)-1-(3-((2-chloro-4-(((2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)methyl)-5-methoxyphenyl)amino)-3-oxopropyl)piperidin-4-yl [1,1'-biphenyl]-2-ylcarbamate (TD-5959, GSK961081, batefenterol): first-in-class dual pharmac
Topics: Administration, Inhalation; Adrenergic beta-2 Receptor Agonists; Animals; Carbamates; CHO Cells; Cricetulus; Drug Discovery; Guinea Pigs; HEK293 Cells; Humans; Lung; Models, Molecular; Muscarinic Antagonists; Pulmonary Disease, Chronic Obstructive; Quinolones | 2015 |
Tenofovir alafenamide for HIV infection: is less more?
Topics: Adenine; Alanine; Anti-HIV Agents; Carbamates; Cobicistat; Deoxycytidine; Emtricitabine; Female; HIV Infections; Humans; Male; Organophosphonates; Quinolones; Tenofovir; Thiazoles | 2015 |
Infectious disease: New HIV-1 prodrug shows promise in phase III trials.
Topics: Adenine; Anti-HIV Agents; Carbamates; Deoxycytidine; Female; HIV Infections; Humans; Male; Organophosphonates; Quinolones; Thiazoles | 2015 |
New drugs 2016, part 2.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzimidazoles; Carbamates; Drug Approval; Drug Therapy; Humans; Imidazoles; Nitriles; Pyridines; Pyrrolidines; Quinolones; Thiophenes; Triazoles; United States; United States Food and Drug Administration; Valine | 2016 |