carbamates and calpain

carbamates has been researched along with calpain in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (3.23)18.2507
2000's6 (19.35)29.6817
2010's22 (70.97)24.3611
2020's2 (6.45)2.80

Authors

AuthorsStudies
Angelastro, MR; Bey, P; Emary, B; Flynn, GA; Friedrich, D; Hwang, KK; Kim, HO; Koehl, JR; Linnik, MD; Marquart, AL; Mehdi, S; Nieduzak, TR; Peet, NP; Vaz, RJ; Webster, ME; White, JN1
Azuma, M; Nakajima, E; Oka, T; Shearer, TR; Tamada, Y; Tochigi, A; Walkup, RD1
Azuma, M; Nakajima, T; Oka, T; Shearer, TR; Tamada, Y1
Asmuth, DM; Kung, HJ; Libertini, SJ; Mudryj, M; Rodriguez, V; Tepper, CG1
Campbell, RL; Cuerrier, D; Davies, PL; Li, Z; Powers, JC; Qian, J1
Inoue, J; Shirasaki, Y; Takahashi, H; Yamaguchi, M1
Azuma, M; Ma, H; Shearer, TR; Tochigi, A1
Hara, H; Inokuchi, Y; Matsunaga, N; Nakajima, Y; Oka, T; Shimazawa, M; Suemori, S; Yamamoto, T1
Matsuyoshi, H; Obata, K; Ohga, Y; Takaki, M; Taniguchi, S; Yoshikawa, Y; Zhang, GX1
Asada, K; Matsuyoshi, H; Obata, K; Takaki, M; Taniguchi, S; Yoshikawa, Y; Zhang, GX1
Hara, H; Imai, S; Nakanishi, T; Shimazawa, M; Tsuruma, K1
Azuma, M; Hammond, KB; Nakajima, E; Rosales, JL; Shearer, TR1
Azuma, M; Nakajima, T; Shearer, TR1
Himori, N; Nakazawa, T; Omodaka, K; Ryu, M; Saido, T; Shanab, AY; Shi, D; Takano, J; Watanabe, R; Yasuda, M; Yokoyama, Y1
Bains, M; Barnes, CC; Cebak, JE; Geddes, JW; Gilmer, LK; Hall, ED; Thompson, SN1
Ito, H; Mitsuyama, S; Obata, K; Takaki, M; Takeshita, D; Tanaka, M; Taniguchi, S; Yoshikawa, Y; Zhang, GX1
Amamoto, M; Azuma, M; Hattori, S; Hayasaka, K; Hirotsune, S; Kataoka, Y; Kato, M; Kumamoto, K; Miyakawa, T; Oka, Y; Sato, M; Takao, K; Tamura, Y; Toba, S; Tominaga, K; Wanibuchi, H; Wynshaw-Boris, A; Yamada, M1
Azuma, M; Hammond, KB; Nakajima, E; Shearer, TR2
Azuma, M; Banik, NL; Inoue, J; Knaryan, VH; Park, S; Samantaray, S1
Azuma, M; Banik, NL; Beeson, C; Haque, A; Inoue, J; Smith, A; Trager, N; Wallace Iv, G1
Azuma, M; Oka, T; Shearer, TR; Suzuki, R; Tamada, Y1
Rosenberger, TA1
Himori, N; Maruyama, K; Nakazawa, T; Nishiguchi, KM; Omodaka, K; Ryu, M; Yamamoto, K; Yasuda, M; Yokoyama, Y1
Agarwal, S; Chiu, A; Grinkina, N; Lin, F; Rubenstein, R; Sharma, DR; Wang, KK; Yang, Z1
Azuma, M; Banik, NL; Inoue, J; Ray, SK; Rohrer, B; Samantaray, S; Smith, AW; Wheless, L1
Azuma, M; Banik, NL; Chauhan, A; Das, A; Hogan, EL; Inoue, J; Nozaki, K; Podbielska, M; Ray, SK; Smith, AW1
Aluja, D; Garcia-Dorado, D; Hernando, V; Inserte, J; Poncelas, M; Vilardosa, U1
Aluja, D; Garcia-Dorado, D; Iñiguez, MÁ; Inserte, J; Mayor, F; Penela, P; Ramos, P; Ribas, C1
Asano, T; Fujioka, H; Fujita, K; Ito, A; Kamiya, M; Kobayashi, W; Kunikata, H; Nagayo, Y; Nakazawa, T; Nishiguchi, KM; Sato, K; Tsuda, S; Urano, Y1
Azuma, M; Kobayashi-Otsugu, M; Nakajima, E; Orihara, K; Shearer, TR1

Other Studies

31 other study(ies) available for carbamates and calpain

ArticleYear
Hydroxyoxazolidines as alpha-aminoacetaldehye equivalents: novel inhibitors of calpain.
    Bioorganic & medicinal chemistry letters, 1999, Aug-16, Volume: 9, Issue:16

    Topics: Calpain; Carbamates; Magnetic Resonance Spectroscopy; Oxazoles; Protease Inhibitors

1999
Amelioration of retinal degeneration and proteolysis in acute ocular hypertensive rats by calpain inhibitor ((1S)-1-((((1S)-1-benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester.
    Neuroscience, 2006, Sep-15, Volume: 141, Issue:4

    Topics: Animals; Calcium-Binding Proteins; Calpain; Carbamates; Disease Models, Animal; Drug Administration Routes; Glycoproteins; Haplorhini; Humans; Intraocular Pressure; Ocular Hypertension; Rats; Rats, Sprague-Dawley; Retinal Degeneration; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Staining and Labeling; Time Factors

2006
Contribution of calpains to photoreceptor cell death in N-methyl-N-nitrosourea-treated rats.
    Experimental neurology, 2007, Volume: 204, Issue:1

    Topics: Animals; Calcium; Calpain; Carbamates; Cell Death; Cyclin-Dependent Kinase 5; Female; In Vitro Techniques; Injections, Intraperitoneal; Methylnitrosourea; Nerve Degeneration; Peptide Hydrolases; Phosphotransferases; Photoreceptor Cells, Vertebrate; Rats; Rats, Sprague-Dawley; Retina; Spectrin

2007
Evidence for calpain-mediated androgen receptor cleavage as a mechanism for androgen independence.
    Cancer research, 2007, Oct-01, Volume: 67, Issue:19

    Topics: Androgens; Animals; Apoptosis; Calpain; Carbamates; Cell Line, Tumor; Dipeptides; Enzyme Activation; Furans; Humans; Ionomycin; Male; Mice; Mice, Nude; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Receptors, Androgen; Sulfonamides; Transcriptional Activation; Transfection; Transplantation, Heterologous

2007
Cocrystal structures of primed side-extending alpha-ketoamide inhibitors reveal novel calpain-inhibitor aromatic interactions.
    Journal of medicinal chemistry, 2008, Sep-11, Volume: 51, Issue:17

    Topics: Amino Acids, Aromatic; Animals; Calpain; Carbamates; Crystallography, X-Ray; Dipeptides; Glycoproteins; Protein Conformation; Rats; Structure-Activity Relationship

2008
Molecular design to enhance the penetration into the retina via ocular instillation.
    Bioorganic & medicinal chemistry letters, 2008, Oct-01, Volume: 18, Issue:19

    Topics: Administration, Oral; Animals; Calpain; Carbamates; Drug Design; Enzyme Inhibitors; Humans; Injections, Intravenous; Macaca fascicularis; Molecular Structure; Rabbits; Retina; Structure-Activity Relationship

2008
Calpain inhibitor SNJ-1945 attenuates events prior to angiogenesis in cultured human retinal endothelial cells.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2009, Volume: 25, Issue:5

    Topics: Angiogenesis Inhibitors; Calpain; Carbamates; Cell Movement; Cells, Cultured; Endothelial Cells; Endothelium, Vascular; Humans; Microvessels; Neovascularization, Physiologic; Retina; Vascular Endothelial Growth Factor A

2009
A novel calpain inhibitor, ((1S)-1-((((1S)-1-Benzyl-3-cyclopropylamino-2,3-di-oxopropyl)amino)carbonyl)-3-methylbutyl)carbamic acid 5-methoxy-3-oxapentyl ester (SNJ-1945), reduces murine retinal cell death in vitro and in vivo.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:2

    Topics: Administration, Oral; Animals; Calpain; Carbamates; Cell Line; Cell Survival; Glycoproteins; Injections, Intraperitoneal; Male; Mice; Mice, Inbred Strains; N-Methylaspartate; Retina; Retinal Degeneration; Retinal Ganglion Cells

2010
Cardioprotective effects of a novel calpain inhibitor SNJ-1945 for reperfusion injury after cardioplegic cardiac arrest.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 298, Issue:2

    Topics: Animals; Calcium; Calcium Channels, L-Type; Calpain; Carbamates; Cardiotonic Agents; Carrier Proteins; Disease Models, Animal; Heart Arrest, Induced; Male; Microfilament Proteins; Myocardial Reperfusion Injury; Oxygen Consumption; Rats; Rats, Wistar; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Ventricular Dysfunction, Left

2010
A cardioprotective agent of a novel calpain inhibitor, SNJ-1945, exerts beta1 actions on left ventricular mechanical work and energetics.
    American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:2

    Topics: Adrenergic beta-Antagonists; Animals; Calpain; Carbamates; Cardiotonic Agents; Cysteine Proteinase Inhibitors; Energy Metabolism; Excitation Contraction Coupling; Heart Ventricles; Male; Oxygen Consumption; Perfusion; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Stroke Volume; Time Factors; Ventricular Function, Left; Ventricular Pressure

2010
Calpain inhibitor protects cells against light-induced retinal degeneration.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:3

    Topics: Animals; Apoptosis; Calpain; Carbamates; Caspase 3; Caspase 7; Electroretinography; Light; Male; Mice; Mice, Inbred Strains; Phosphotransferases; Photoreceptor Cells; Retina; Retinal Degeneration; Spectrin

2010
Calpain, not caspase, is the causative protease for hypoxic damage in cultured monkey retinal cells.
    Investigative ophthalmology & visual science, 2011, Sep-01, Volume: 52, Issue:10

    Topics: Animals; Apoptosis; Biomarkers; Calpain; Carbamates; Caspase 3; Caspase Inhibitors; Cell Count; Cell Proliferation; Cells, Cultured; Fluorescent Antibody Technique, Indirect; Hypoxia; Immunoblotting; In Situ Nick-End Labeling; Macaca mulatta; Neuroglia; Oligopeptides; Photoreceptor Cells, Vertebrate; Recoverin; Reperfusion Injury; Rhodopsin; Spectrin; Vimentin

2011
Involvement of calpain 2 in ionomycin-induced cell death in cultured mouse lens epithelial cells.
    Current eye research, 2011, Volume: 36, Issue:10

    Topics: Animals; Calcium; Calcium Ionophores; Calpain; Carbamates; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Epithelial Cells; Ionomycin; L-Lactate Dehydrogenase; Lens, Crystalline; Mice; Mice, Transgenic; Necrosis; Spectrin

2011
Critical role of calpain in axonal damage-induced retinal ganglion cell death.
    Journal of neuroscience research, 2012, Volume: 90, Issue:4

    Topics: Amino Acids; Animals; Axons; Brain-Derived Neurotrophic Factor; Calcium-Binding Proteins; Calpain; Carbamates; Carrier Proteins; Cell Count; Cell Death; Cells, Cultured; Disease Models, Animal; Enzyme Inhibitors; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Microfilament Proteins; Neurofilament Proteins; Optic Nerve Injuries; Retina; Retinal Ganglion Cells; Stilbamidines; Time Factors; Tubulin

2012
Pharmacological analysis of the cortical neuronal cytoskeletal protective efficacy of the calpain inhibitor SNJ-1945 in a mouse traumatic brain injury model.
    Journal of neurochemistry, 2013, Volume: 125, Issue:1

    Topics: Animals; Brain Injuries; Calpain; Carbamates; Cerebral Cortex; Cytoskeleton; Dose-Response Relationship, Drug; Male; Mice; Neurons; Spectrin

2013
A new calpain inhibitor protects left ventricular dysfunction induced by mild ischemia-reperfusion in in situ rat hearts.
    The journal of physiological sciences : JPS, 2013, Volume: 63, Issue:2

    Topics: Animals; Biomechanical Phenomena; Blotting, Western; Calcium; Calpain; Carbamates; Cardiotonic Agents; Carrier Proteins; Cysteine Proteinase Inhibitors; Disease Models, Animal; Male; Microfilament Proteins; Myocardial Reperfusion Injury; Myocardium; Oxygen Consumption; Rats; Rats, Wistar; Stroke Volume; Time Factors; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure

2013
Post-natal treatment by a blood-brain-barrier permeable calpain inhibitor, SNJ1945 rescued defective function in lissencephaly.
    Scientific reports, 2013, Volume: 3

    Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Administration, Oral; Animals; Blood-Brain Barrier; Calpain; Carbamates; Cell Line; Fluorodeoxyglucose F18; Glycoproteins; Humans; Lissencephaly; Male; Mice; Microtubule-Associated Proteins; Motor Activity; Nerve Growth Factor; Neurons; Positron-Emission Tomography; Receptors, GABA

2013
Activation of the mitochondrial caspase pathway and subsequent calpain activation in monkey RPE cells cultured under zinc depletion.
    Eye (London, England), 2014, Volume: 28, Issue:1

    Topics: Animals; Apoptosis; Calpain; Carbamates; Caspase Inhibitors; Caspases; Cells, Cultured; Chelating Agents; Enzyme Activation; Ethylenediamines; Macaca mulatta; Microscopy, Phase-Contrast; Mitochondria; Oligopeptides; Retinal Pigment Epithelium; Signal Transduction; Time Factors; Zinc

2014
Calpain protease causes hypoxia-induced proteolysis in cultured human retina.
    Current eye research, 2014, Volume: 39, Issue:4

    Topics: Aged; Aged, 80 and over; Animals; Calpain; Carbamates; Cell Death; Cells, Cultured; Disease Models, Animal; Female; Haplorhini; Humans; Hypoxia; Immunoblotting; Male; Middle Aged; Peptide Hydrolases; Proteolysis; Retina

2014
SNJ-1945, a calpain inhibitor, protects SH-SY5Y cells against MPP(+) and rotenone.
    Journal of neurochemistry, 2014, Volume: 130, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Blotting, Western; Calcium; Calpain; Carbamates; Cell Line, Tumor; Cell Survival; Cysteine Proteinase Inhibitors; Dopamine Agents; Enzyme Activation; Fluorescent Antibody Technique; Humans; Inflammation Mediators; Neuroprotective Agents; Reactive Oxygen Species; Rotenone; Uncoupling Agents

2014
Effects of a novel orally administered calpain inhibitor SNJ-1945 on immunomodulation and neurodegeneration in a murine model of multiple sclerosis.
    Journal of neurochemistry, 2014, Volume: 130, Issue:2

    Topics: Animals; Blotting, Western; Calpain; Carbamates; Cell Proliferation; Cell Separation; Cysteine Proteinase Inhibitors; Disease Progression; Encephalomyelitis, Autoimmune, Experimental; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunohistochemistry; Immunomodulation; In Situ Nick-End Labeling; Male; Mice; Monocytes; Multiple Sclerosis; Nerve Degeneration; Real-Time Polymerase Chain Reaction; T-Lymphocytes, Helper-Inducer

2014
Degeneration and dysfunction of retinal neurons in acute ocular hypertensive rats: involvement of calpains.
    Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics, 2014, Volume: 30, Issue:5

    Topics: Acute Disease; Animals; Calpain; Carbamates; Male; Ocular Hypertension; Rats; Rats, Sprague-Dawley; Retinal Degeneration; Retinal Neurons

2014
Targeting calpain-mediated proteolysis and peptide signaling as a strategy to reduce injury in multiple sclerosis.
    Journal of neurochemistry, 2014, Volume: 130, Issue:2

    Topics: Animals; Calpain; Carbamates; Cysteine Proteinase Inhibitors; Encephalomyelitis, Autoimmune, Experimental; Immunomodulation; Male; Multiple Sclerosis; Nerve Degeneration

2014
The role of calpain in an in vivo model of oxidative stress-induced retinal ganglion cell damage.
    Biochemical and biophysical research communications, 2014, Sep-05, Volume: 451, Issue:4

    Topics: Amidines; Animals; Apoptosis; Calpain; Carbamates; Carrier Proteins; Glycoproteins; Male; Mice; Mice, Inbred C57BL; Microfilament Proteins; Models, Animal; Oxidative Stress; Retinal Ganglion Cells

2014
PrP
    Behavioural brain research, 2018, 03-15, Volume: 340

    Topics: Animals; Avoidance Learning; Brain; Brain Injuries, Traumatic; Calpain; Carbamates; Disease Models, Animal; Enzyme Inhibitors; Female; Head Injuries, Closed; Male; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Transgenic; Neuroglia; Neurons; PrPC Proteins; Spatial Memory

2018
Calpain inhibition reduces structural and functional impairment of retinal ganglion cells in experimental optic neuritis.
    Journal of neurochemistry, 2016, Volume: 139, Issue:2

    Topics: Animals; Calpain; Carbamates; Cell Death; Electroretinography; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Gliosis; Male; Mice; Myelin Basic Protein; Neuroprotective Agents; Nystagmus, Optokinetic; Optic Neuritis; Photic Stimulation; Retinal Ganglion Cells; Visual Acuity

2016
Neuron-microglia interaction induced bi-directional cytotoxicity associated with calpain activation.
    Journal of neurochemistry, 2016, Volume: 139, Issue:3

    Topics: Animals; Calpain; Carbamates; Cell Survival; Cysteine Proteinase Inhibitors; Dipeptides; Enzyme Activation; Gene Knockdown Techniques; Humans; Inflammation; Microglia; Motor Neurons; Multiple Sclerosis; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Primary Cell Culture; Rats; Rats, Sprague-Dawley; Th1 Cells; Th17 Cells

2016
Delayed, oral pharmacological inhibition of calpains attenuates adverse post-infarction remodelling.
    Cardiovascular research, 2017, Jul-01, Volume: 113, Issue:8

    Topics: Animals; Calcium-Binding Proteins; Calpain; Carbamates; Glycoproteins; Heart; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats, Sprague-Dawley

2017
Calpains mediate isoproterenol-induced hypertrophy through modulation of GRK2.
    Basic research in cardiology, 2019, 03-26, Volume: 114, Issue:3

    Topics: Animals; Calpain; Carbamates; Disease Models, Animal; G-Protein-Coupled Receptor Kinase 2; Hypertrophy, Left Ventricular; Isoproterenol; Male; Myocardium; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Up-Regulation

2019
Companion Diagnosis for Retinal Neuroprotective Treatment by Real-Time Imaging of Calpain Activation Using a Novel Fluorescent Probe.
    Bioconjugate chemistry, 2020, 09-16, Volume: 31, Issue:9

    Topics: Animals; Calpain; Carbamates; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Fluorescent Dyes; Humans; Neuroprotective Agents; Optical Imaging; Rats; Rats, Sprague-Dawley; Retina; Rhodamines

2020
Activation of Cytosolic Calpain, Not Caspase, Is Underlying Mechanism for Hypoxic RGC Damage in Human Retinal Explants.
    Investigative ophthalmology & visual science, 2020, 11-02, Volume: 61, Issue:13

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Calpain; Carbamates; Caspase 3; Cells, Cultured; Child; Cytosol; DNA Fragmentation; Enzyme Activation; Humans; Hypoxia; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Macaca mulatta; Middle Aged; Retinal Diseases; Retinal Ganglion Cells

2020