carbamates and brecanavir

carbamates has been researched along with brecanavir in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carter, HL; Danger, D; Furfine, ES; Hanlon, MH; Kaldor, IW; Miller, JF; Porter, DJ; Samano, VA; Shu, AY; Spaltenstein, A1
Anderson, MT; Fernandez, P; Ford, SL; Johnson, MA; Murray, SC; Reddy, YS; Stein, DS1
Anderson, MT; Ford, SL; Johnson, MA; Murray, SC; Ng-Cashin, J; Reddy, YS1
Garges, HP; Lalezari, JP; Tomkins, SA; Ward, DJ1
Boone, L; Craig, C; Ferris, R; Furfine, E; Griffin, P; Hale, M; Hanlon, M; Harvey, R; Hazen, R; Kaldor, I; Miller, J; Ray, J; Samano, V; Spaltenstein, A; St Clair, M; Tung, R; Yates, P1
Baughman, TM; Johns, BA; Temelkoff, DP; Velthuisen, EJ; Weatherhead, JG1

Trials

3 trial(s) available for carbamates and brecanavir

ArticleYear
Single-dose safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus protease inhibitor.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:6

    Topics: Administration, Oral; Adult; Area Under Curve; Benzodioxoles; Capsules; Carbamates; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Flatulence; Gels; Half-Life; Headache; HIV Protease Inhibitors; Humans; Male; Middle Aged; Nausea; Ritonavir

2006
Safety and pharmacokinetics of brecanavir, a novel human immunodeficiency virus type 1 protease inhibitor, following repeat administration with and without ritonavir in healthy adult subjects.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:4

    Topics: Adult; Area Under Curve; Benzodioxoles; Carbamates; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; HIV Infections; HIV Protease Inhibitors; HIV-1; Humans; Male; Middle Aged; Ritonavir; Safety

2007
Preliminary safety and efficacy data of brecanavir, a novel HIV-1 protease inhibitor: 24 week data from study HPR10006.
    The Journal of antimicrobial chemotherapy, 2007, Volume: 60, Issue:1

    Topics: Adult; Amino Acid Substitution; Anti-HIV Agents; Benzodioxoles; Carbamates; CD4 Lymphocyte Count; Drug Resistance, Viral; Drug Therapy, Combination; Female; HIV Infections; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Male; Middle Aged; Reverse Transcriptase Inhibitors; Ritonavir; RNA, Viral; Treatment Outcome

2007

Other Studies

4 other study(ies) available for carbamates and brecanavir

ArticleYear
Inhibition of wild-type and mutant human immunodeficiency virus type 1 proteases by GW0385 and other arylsulfonamides.
    Biochemistry, 2004, Nov-16, Volume: 43, Issue:45

    Topics: Amino Acid Substitution; Binding, Competitive; Carbamates; Chromatography, Affinity; Chromatography, Gel; Dextrans; Dimerization; Furans; HIV Protease; HIV Protease Inhibitors; HIV-1; Hydrolysis; Kinetics; Protein Binding; Saquinavir; Spectrometry, Fluorescence; Substrate Specificity; Sulfonamides

2004
Brecanavir's hopes dashed.
    AIDS patient care and STDs, 2007, Volume: 21, Issue:2

    Topics: Anti-HIV Agents; Benzodioxoles; Carbamates; Chemistry, Pharmaceutical; Clinical Trials, Phase II as Topic; Drug Approval; Humans

2007
In vitro antiviral activity of the novel, tyrosyl-based human immunodeficiency virus (HIV) type 1 protease inhibitor brecanavir (GW640385) in combination with other antiretrovirals and against a panel of protease inhibitor-resistant HIV.
    Antimicrobial agents and chemotherapy, 2007, Volume: 51, Issue:9

    Topics: Algorithms; Anti-Retroviral Agents; Benzodioxoles; Blood Proteins; Carbamates; Cell Line; Drug Resistance, Viral; HeLa Cells; HIV Protease Inhibitors; HIV-1; Humans; Orosomucoid; Phenotype; Serum; Serum Albumin; Tyrosine

2007
Synthesis and pharmacokinetic profile of highly deuterated brecanavir analogs.
    European journal of medicinal chemistry, 2013, Volume: 63

    Topics: Administration, Intravenous; Animals; Area Under Curve; Benzodioxoles; Carbamates; Deuterium; Hepatocytes; HIV Protease Inhibitors; Humans; Metabolic Clearance Rate; Models, Chemical; Molecular Structure; Rats

2013