carbamates and avn 944

carbamates has been researched along with avn 944 in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (66.67)	29.6817
2010's	1 (16.67)	24.3611
2020's	1 (16.67)	2.80

Authors

Authors	Studies
Huang, M; Itahana, K; Ji, Y; Mitchell, B; Zhang, Y	1
Floryk, D; Thompson, TC	1
Bol, DK; Genna, T; Hamilton, JM; Harding, MW	1
Huang, M; Itahana, K; Mitchell, BS; Zhang, Y	1
Dunham, EC; Feldmann, H; Groseth, A; Hoenen, T; Leske, A; Shifflett, K; Watt, A	1
Almazan, F; Ávila-Pérez, G; de la Torre, JC; Martinez-Sobrido, L; Morales Vasquez, D; Nogales, A; Park, JG	1

Trials

1 trial(s) available for carbamates and avn 944

Article	Year
A phase I dose-ranging study of the pharmacokinetics, pharmacodynamics, safety, and tolerability of AVN944, an IMPDH inhibitor, in healthy male volunteers. Journal of clinical pharmacology, 2009, Volume: 49, Issue:1 Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents; Carbamates; Double-Blind Method; Humans; IMP Dehydrogenase; Male; Middle Aged; Phenylurea Compounds; Young Adult	2009

Article

Year

A phase I dose-ranging study of the pharmacokinetics, pharmacodynamics, safety, and tolerability of AVN944, an IMPDH inhibitor, in healthy male volunteers.

Journal of clinical pharmacology, 2009, Volume: 49, Issue:1

Topics: Administration, Oral; Adolescent; Adult; Antineoplastic Agents; Carbamates; Double-Blind Method; Humans; IMP Dehydrogenase; Male; Middle Aged; Phenylurea Compounds; Young Adult

2009

Other Studies

5 other study(ies) available for carbamates and avn 944

Article	Year
Guanine nucleotide depletion inhibits pre-ribosomal RNA synthesis and causes nucleolar disruption. Leukemia research, 2008, Volume: 32, Issue:1 Topics: Animals; Carbamates; Cell Line, Tumor; Cell Nucleolus; Cell Proliferation; Cell Survival; Gene Expression Regulation; Genes, p53; Guanine Nucleotides; Humans; IMP Dehydrogenase; K562 Cells; Mice; Mycophenolic Acid; Phenylurea Compounds; Reverse Transcriptase Polymerase Chain Reaction; RNA Precursors; RNA, Ribosomal	2008
Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells. International journal of cancer, 2008, Nov-15, Volume: 123, Issue:10 Topics: Androgens; Apoptosis; Carbamates; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Humans; IMP Dehydrogenase; Male; Phenylurea Compounds; Prostatic Neoplasms	2008
Depletion of guanine nucleotides leads to the Mdm2-dependent proteasomal degradation of nucleostemin. Cancer research, 2009, Apr-01, Volume: 69, Issue:7 Topics: Carbamates; Carrier Proteins; Cell Line, Tumor; GTP-Binding Proteins; Guanosine Triphosphate; Humans; Imidazoles; IMP Dehydrogenase; K562 Cells; Nuclear Proteins; Nucleolin; Phenylurea Compounds; Phosphoproteins; Piperazines; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Proto-Oncogene Proteins c-mdm2; RNA-Binding Proteins; RNA, Messenger	2009
Lifecycle modelling systems support inosine monophosphate dehydrogenase (IMPDH) as a pro-viral factor and antiviral target for New World arenaviruses. Antiviral research, 2018, Volume: 157 Topics: Animals; Antiviral Agents; Carbamates; Cell Line; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; IMP Dehydrogenase; Junin virus; Phenylurea Compounds; Reverse Genetics; Transcription, Genetic; Virus Cultivation; Virus Replication	2018
Identification of Inhibitors of ZIKV Replication. Viruses, 2020, 09-18, Volume: 12, Issue:9 Topics: A549 Cells; Animals; Antiviral Agents; Apoptosis; Azauridine; Biphenyl Compounds; Carbamates; Cell Survival; Chlorocebus aethiops; Drug Repositioning; Guillain-Barre Syndrome; Humans; Microcephaly; Phenylurea Compounds; Uganda; Vero Cells; Virus Replication; Zika Virus; Zika Virus Infection	2020