carbamates and apcin

carbamates has been researched along with apcin in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (45.45)24.3611
2020's6 (54.55)2.80

Authors

AuthorsStudies
Dimova, N; King, RW; Luo, X; Meaders, J; Pfaff, KL; Sackton, KL; Sackton, TB; Sigoillot, F; Tian, W; Yu, H; Zeng, X; Zhang, M1
Kawatani, M; Osada, H1
De Bruyne, E; De Veirman, K; Fostier, K; Hose, D; Kassambara, A; King, RW; Leleu, X; Lub, S; Maes, A; Maes, K; Menu, E; Moreaux, J; Van Valckenborgh, E; Vanderkerken, K1
Dai, X; Ding, Q; Gan, W; Li, M; Mitsiades, N; Wan, L; Wei, W; Wu, F; Zhang, J1
Gao, Y; Shang, G; Wang, Y; Zhang, B1
Scarberry, L; Schrock, MS; Stromberg, BR; Summers, MK1
Bartlett, E; Cobban, A; Douglas, P; Jenkins, NP; Kettenbach, AN; Lees-Miller, SP; Radhamani, S; Roveredo, J; Ye, R1
Chen, Z; Hu, G; Huang, F; Huang, P; Le, X; Li, Q; Ma, J; Yang, H; Yang, J1
Gao, N; Guo, C; Kong, F; Lv, Y; Sun, X; Xiu, X1
Ding, Y; He, L; Pan, Y; Song, X; Yu, S; Zhang, C; Zheng, C1
Collier, DM; Park, F; Regner, KR; Seif, C; Swanson, M; Yang, CY; Yun, J1

Reviews

2 review(s) available for carbamates and apcin

ArticleYear
[Chemical biology and novel molecular-targeted agents in cancer therapy].
    Nihon rinsho. Japanese journal of clinical medicine, 2015, Volume: 73, Issue:8

    Topics: Aminoquinolines; Antineoplastic Agents; Carbamates; Cell Cycle; Coumarins; Diamines; Diterpenes, Kaurane; Drug Discovery; Humans; Molecular Targeted Therapy; Neoplasms; Pyrazoles; Quinolines

2015
APC/C ubiquitin ligase: Functions and mechanisms in tumorigenesis.
    Seminars in cancer biology, 2020, Volume: 67, Issue:Pt 2

    Topics: Anaphase-Promoting Complex-Cyclosome; Antigens, CD; Antineoplastic Agents; Carbamates; Cdc20 Proteins; Cdh1 Proteins; Diamines; Genomic Instability; Humans; Molecular Targeted Therapy; Neoplasms

2020

Other Studies

9 other study(ies) available for carbamates and apcin

ArticleYear
Synergistic blockade of mitotic exit by two chemical inhibitors of the APC/C.
    Nature, 2014, Oct-30, Volume: 514, Issue:7524

    Topics: Anaphase-Promoting Complex-Cyclosome; Binding Sites; Carbamates; Cdc20 Proteins; Cell Death; Crystallography, X-Ray; Diamines; Drug Synergism; Mitosis; Protein Binding; Proteolysis; Tosylarginine Methyl Ester; Ubiquitination

2014
Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells.
    Oncotarget, 2016, Jan-26, Volume: 7, Issue:4

    Topics: Anaphase-Promoting Complex-Cyclosome; Antineoplastic Agents, Alkylating; Apoptosis; Blotting, Western; Carbamates; Cdc20 Proteins; Cell Cycle Checkpoints; Cell Proliferation; Diamines; Gene Expression Profiling; Humans; Immunoenzyme Techniques; Melphalan; Mitosis; Multiple Myeloma; Tumor Cells, Cultured

2016
Prostate cancer-associated mutation in SPOP impairs its ability to target Cdc20 for poly-ubiquitination and degradation.
    Cancer letters, 2017, 01-28, Volume: 385

    Topics: Antineoplastic Agents; Carbamates; Cdc20 Proteins; Cullin Proteins; Cyclopentanes; Diamines; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Enzyme Inhibitors; HeLa Cells; Humans; Male; Molecular Targeted Therapy; Mutation; Nuclear Proteins; Prostatic Neoplasms; Protein Interaction Domains and Motifs; Proteolysis; Pyrimidines; Repressor Proteins; Time Factors; Transfection; Ubiquitination

2017
Cdc20 inhibitor apcin inhibits the growth and invasion of osteosarcoma cells.
    Oncology reports, 2018, Volume: 40, Issue:2

    Topics: Apoptosis; Bcl-2-Like Protein 11; Carbamates; Cdc20 Proteins; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Diamines; Disease Progression; Humans; Osteosarcoma; Up-Regulation

2018
Nocodazole-Induced Expression and Phosphorylation of Anillin and Other Mitotic Proteins Are Decreased in DNA-Dependent Protein Kinase Catalytic Subunit-Deficient Cells and Rescued by Inhibition of the Anaphase-Promoting Complex/Cyclosome with proTAME but
    Molecular and cellular biology, 2020, 06-15, Volume: 40, Issue:13

    Topics: A549 Cells; Anaphase-Promoting Complex-Cyclosome; Animals; Antineoplastic Agents; Aurora Kinase A; Carbamates; Cell Cycle Proteins; Contractile Proteins; CRISPR-Cas Systems; Diamines; DNA-Activated Protein Kinase; Down-Regulation; Enzyme Inhibitors; HeLa Cells; Humans; Nocodazole; Phosphorylation; Polo-Like Kinase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Up-Regulation; Xenopus

2020
Discovery of a Dual Tubulin Polymerization and Cell Division Cycle 20 Homologue Inhibitor via Structural Modification on Apcin.
    Journal of medicinal chemistry, 2020, 05-14, Volume: 63, Issue:9

    Topics: Antineoplastic Agents; Apoptosis; Carbamates; Cdc20 Proteins; Cell Movement; Cell Proliferation; Diamines; Drug Discovery; Drug Screening Assays, Antitumor; Hep G2 Cells; Humans; Microtubules; Mitosis; Molecular Structure; Protein Binding; Structure-Activity Relationship; Surface Plasmon Resonance; Tubulin Modulators

2020
CDC20 inhibitor Apcin inhibits embryo implantation in vivo and in vitro.
    Cell biochemistry and function, 2020, Volume: 38, Issue:6

    Topics: Animals; Carbamates; Cdc20 Proteins; Cell Adhesion; Cell Proliferation; Cells, Cultured; Diamines; Embryo Implantation; Endometrium; Epithelial Cells; Estrogens; Estrus; Female; Humans; Menstrual Cycle; Mice; Uterus

2020
Apcin inhibits the growth and invasion of glioblastoma cells and improves glioma sensitivity to temozolomide.
    Bioengineered, 2021, Volume: 12, Issue:2

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Brain Neoplasms; Carbamates; Cell Line, Tumor; Cell Proliferation; Diamines; Drug Resistance, Neoplasm; Glioblastoma; Glioma; Humans; Neoplasm Invasiveness; Signal Transduction; Temozolomide

2021
Identification of cell division cycle protein 20 in various forms of acute and chronic kidney injury in mice.
    American journal of physiology. Renal physiology, 2023, 08-01, Volume: 325, Issue:2

    Topics: Acute Kidney Injury; Animals; Carbamates; Cell Cycle Proteins; Kidney; Mice; Ureteral Obstruction

2023