carbachol has been researched along with tyrosine in 75 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 17 (22.67) | 18.7374 |
| 1990's | 35 (46.67) | 18.2507 |
| 2000's | 21 (28.00) | 29.6817 |
| 2010's | 2 (2.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cooper, JR; Nowycky, MC; Roth, RH; Sgaragli, GP | 1 |
| Besson, MJ; Giorguieff, MF; Glowinski, J; Le Floc'h, ML; Westfall, TC | 1 |
| Gutkind, JS; Robbins, KC | 1 |
| Kubota, K; Matsuoka, Y; Nagahamaya, K; Shirane, M; Sunagane, N; Tsunematsu, R; Uruno, T; Wada, K | 1 |
| Benhamou, M; Gutkind, JS; Robbins, KC; Siraganian, RP; Stephan, V | 1 |
| Brann, MR; Gdula, D; Wess, J | 1 |
| Debinski, WK; Kuchel, OG | 1 |
| Izumi, F; Wada, A; Yanagihara, N; Yokota, K | 1 |
| Izumi, F; Wada, A; Yanagihara, N | 1 |
| Baraban, JM; Huganir, RL; Stratton, KR; Worley, PF | 1 |
| Buu, NT; Cantin, M; Debinski, W; Genest, J; Kuchel, O | 1 |
| Houchi, H; Nakanishi, A; Ohuchi, T; Oka, M; Uddin, MM | 1 |
| Houchi, H; Misbahuddin, M; Morita, K; Nakanishi, A; Oka, M | 1 |
| Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H | 1 |
| Levine, M | 1 |
| Houchi, H | 1 |
| Hörtnagl, H; Schöpf, JA; Winkler, H; zur Nedden, G | 1 |
| Agid, Y; Bouvet, D; Glowinski, J; Javoy, F | 1 |
| Dickens, G; Guroff, G; Ikeno, T; Lloyd, T | 1 |
| Izumi, F; Kobayashi, H; Sakurai, S; Wada, A; Yanagihara, N | 1 |
| Jones, CA; Marchbanks, RM | 1 |
| Beaven, MA; Hirasawa, N; Kinet, JP; Scharenberg, A; Yamamura, H | 1 |
| Soltoff, SP; Toker, A | 1 |
| Felder, CC; Gusovsky, F; Kohn, EC; Ma, AL; MacArthur, L | 1 |
| Felder, CC; Gusovsky, F; Kohn, EC; Lueders, JE | 1 |
| Bombien, E; Offermanns, S; Schultz, G | 1 |
| Beaven, MA; Santini, F | 1 |
| Breu, J; Petryniak, MA; Slack, BE; Srivastava, K; Wurtman, RJ | 1 |
| Jakubík, J; Tucek, S | 1 |
| Fasselt, B; Homann, D; Hüwe, SM; Jakobs, KH; Rümenapp, U; Sandmann, J; Schmidt, M | 1 |
| Berl, T; Heasley, LE; Senkfor, SI; Strasheim, A; Teitelbaum, I; Winitz, S | 1 |
| Kreienkamp, HJ; Papanikolaou, F; Quiram, P; Sine, SM; Taylor, P | 1 |
| Blüml, K; Mutschler, E; Wess, J | 1 |
| Goldman, PS; Nathanson, NM | 1 |
| Akk, G; Auerbach, A; Chen, J; Sine, S; Zhang, Y | 1 |
| Ichida, T; Tajima, Y; Takuma, T | 1 |
| Brann, MR; Burstein, ES; Spalding, TA | 1 |
| el-Fakahany, EE; Lee, SY; Zhu, SZ | 1 |
| Ito, Y; Kanoh, H; Nakashima, S; Nozawa, Y | 1 |
| Crespo, P; Gutkind, JS; Lopez-Ilasaca, M; Pellici, PG; Wetzker, R | 1 |
| Petryniak, MA; Slack, BE; Wurtman, RJ | 1 |
| Dreger, M; Herrmann, A; Hucho, F; Krauss, M | 1 |
| Alessandro, R; Biagini, G; Kohn, EC; Pugnaloni, A | 1 |
| Goyal, RK; Hirano, I; Kakkar, R; Saha, JK; Szymanski, PT | 1 |
| Schimerlik, MI; Sheehan, DM; Vogel, WK | 1 |
| Osaka, H; Sugiyama, N; Taylor, P | 1 |
| Bradford, MD; Soltoff, SP | 1 |
| Blin, N; Blüml, K; Mutschler, E; Wess, J | 1 |
| Hanai, H; Kajimura, M; Kaneko, E; Kodaira, M; Lin, S; Takeuchi, K | 1 |
| Pausawasdi, N; Takeuchi, Y; Todisco, A | 1 |
| Dohi, S; Nakashima, S; Nozawa, Y; Ohguchi, K; Tan, Z | 1 |
| Barrett, KE; Keely, SJ | 1 |
| Benbernou, N; Durum, SK; Muegge, K | 1 |
| García, LJ; Rosado, JA; Salido, GM | 1 |
| Hattori, Y; Kanno, M; Kitabatake, A; Kohya, T; Sasaki, M; Sato, A; Tomita, F | 1 |
| Kamisaki, Y; Maeda, S; Saeki, M | 1 |
| Biden, TJ; Blewitt, M; Kelly, MM; Mitchell, CJ; Wilson, JR | 1 |
| Benes, C; Soltoff, SP | 1 |
| Barrett, KE; Calandrella, S; Chang, N; Keely, SJ; Uribe, JM | 1 |
| Jope, RS; Tucholski, J; Watcharasit, P | 1 |
| del Carmen Boyano-Adánez, M; Gustavsson, L | 1 |
| Babnigg, G; Villereal, ML; Wu, X; Zagranichnaya, T | 1 |
| Broderick, CL; Gold, G; Knierman, MD; Konrad, RJ; Lee, TN; Workman, R | 1 |
| Barrett, KE; Carlstrom, K; Chow, JY | 1 |
| Chiara, DC; Cohen, JB; Dangott, LJ; Eckenhoff, RG | 1 |
| Asano, T; Kato, K; Morishita, R; Narumiya, S; Ueda, H | 1 |
| Barrett, KE; Calandrella, SO; Keely, SJ | 1 |
| Martin, JL; Négrerie, M; Nghiêm, HO | 1 |
| Arruebo, MP; Grasa, L; Murillo, MD; Plaza, MA | 1 |
| Jiang, X; Rozengurt, E; Sinnett-Smith, J | 1 |
| Juan, YS; Kalorin, C; Kogan, BA; Levin, RM; Lin, WY; Mannikarottu, A | 1 |
| Huang, CH; Juan, YS; Levin, RM; Lin, WY; Mannikarottu, A; Schuler, C | 1 |
| Javed, Z; Juan, YS; Kogan, B; Leggett, R; Levin, RM; Li, S; Lin, WY; Mannikarottu, A; Schuler, C; Sokol, R; Strassner, J | 1 |
| Berlot, CH; Bünemann, M; Hein, P; Hoffmann, C; Lohse, MJ; Nuber, S; Winkler, C; Zabel, U; Ziegler, N | 1 |
| Balghi, H; Billet, A; Hanrahan, JW; Luo, Y | 1 |
1 review(s) available for carbachol and tyrosine
| Article | Year |
|---|---|
Muscarinic acetylcholine receptors: structural basis of ligand binding and G protein coupling.
Topics: Amino Acid Sequence; Animals; Carbachol; Cell Membrane; Dose-Response Relationship, Drug; GTP-Binding Proteins; Ligands; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Tyrosine | 1995 |
74 other study(ies) available for carbachol and tyrosine
| Article | Year |
|---|---|
Effect of collagenase on the release of dopamine and acetylcholine from slices of rat corpus striatum.
Topics: Acetylcholine; Amphetamine; Animals; Calcium; Carbachol; Choline; Corpus Striatum; Dopamine; In Vitro Techniques; Male; Microbial Collagenase; Perfusion; Potassium; Rats; Time Factors; Tyrosine | 1975 |
Nicotinic effect of acetylcholine on the release of newly synthesized (3H)dopamine in rat striatal slices and cat caudate nucleus.
Topics: Acetylcholine; Animals; Carbachol; Cats; Caudate Nucleus; Corpus Striatum; Decerebrate State; Dopamine; Female; Hexamethonium Compounds; Male; Mecamylamine; Physostigmine; Rats; Tyrosine | 1976 |
Activation of transforming G protein-coupled receptors induces rapid tyrosine phosphorylation of cellular proteins, including p125FAK and the p130 v-src substrate.
Topics: 1-Phosphatidylinositol 4-Kinase; 3T3 Cells; Animals; Carbachol; Cell Adhesion Molecules; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genes, src; GTP-Binding Proteins; Humans; Mice; Phosphorylation; Phosphotransferases; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Receptors, Muscarinic; Retroviridae Proteins; Signal Transduction; Transfection; Tyrosine | 1992 |
Possible mechanisms of action of the antispasmodic agent tiropramide in the isolated detrusor from rats.
Topics: Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Cytosol; Fura-2; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Papaverine; Parasympatholytics; Rats; Rats, Wistar; Tyrosine; Urinary Bladder | 1992 |
Fc epsilon RI-induced protein tyrosine phosphorylation of pp72 in rat basophilic leukemia cells (RBL-2H3). Evidence for a novel signal transduction pathway unrelated to G protein activation and phosphatidylinositol hydrolysis.
Topics: 3T3 Cells; Animals; Antigens, Differentiation, B-Lymphocyte; Carbachol; Cell Line; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immunoglobulin E; Inositol Phosphates; Isoflavones; Kinetics; Leukemia, Basophilic, Acute; Mice; Models, Biological; Phosphatidylinositols; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Fc; Receptors, IgE; Receptors, Muscarinic; Signal Transduction; Transfection; Type C Phospholipases; Tyrosine | 1992 |
Site-directed mutagenesis of the m3 muscarinic receptor: identification of a series of threonine and tyrosine residues involved in agonist but not antagonist binding.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Binding Sites; Carbachol; Cell Line; Hydrolysis; Ligands; Molecular Sequence Data; Muscarinic Antagonists; Mutagenesis, Site-Directed; Phosphatidylinositols; Plasmids; Rats; Receptors, Muscarinic; Threonine; Tyrosine | 1991 |
Responsiveness of noradrenergic neurons in rat experimental hypertension.
Topics: Animals; Carbachol; Catecholamines; Drug Resistance; Ganglia, Sympathetic; Hypertension; Male; Neurons; Norepinephrine; Parasympathomimetics; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Sodium Chloride; Tyrosine | 1989 |
Intracellular pH and catecholamine synthesis in cultured bovine adrenal medullary cells: effect of extracellular Na+ removal.
Topics: Adrenal Medulla; Animals; Bucladesine; Calcium; Carbachol; Catecholamines; Cattle; Cells, Cultured; Cesium; Chlorides; Culture Media; Dopamine; Epinephrine; Hydrogen-Ion Concentration; Lithium; Lithium Chloride; Norepinephrine; Sodium; Sucrose; Tyrosine; Tyrosine 3-Monooxygenase | 1987 |
Effects of alpha 2-adrenergic agonists on carbachol-stimulated catecholamine synthesis in cultured bovine adrenal medullary cells.
Topics: 2-Hydroxyphenethylamine; Adrenal Medulla; Adrenergic alpha-Agonists; Animals; Calcium; Carbachol; Catecholamines; Cattle; Cells, Cultured; Clonidine; Cyclic AMP; Dose-Response Relationship, Drug; Guanfacine; Guanidines; Octopamine; Oxymetazoline; Phenylacetates; Tyrosine; Tyrosine 3-Monooxygenase; Yohimbine | 1987 |
Muscarinic agonists and phorbol esters increase tyrosine phosphorylation of a 40-kilodalton protein in hippocampal slices.
Topics: Animals; Carbachol; Hippocampus; In Vitro Techniques; Kinetics; Male; Nerve Tissue Proteins; Oxotremorine; Phorbol Esters; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Tyrosine | 1989 |
Atrial natriuretic factor partially inhibits the stimulated catecholamine synthesis in superior cervical ganglia of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atrial Natriuretic Factor; Carbachol; Catecholamines; Dopamine; Female; Ganglia, Sympathetic; Male; Rats; Rats, Inbred Strains; Tyrosine | 1987 |
Phorbol ester stimulates catecholamine synthesis in isolated bovine adrenal medullary cells.
Topics: Adrenal Medulla; Animals; Bucladesine; Calcium; Carbachol; Catecholamines; Cattle; Colforsin; Cyclic AMP; Diterpenes; Enzyme Activation; In Vitro Techniques; Phorbols; Protein Kinase C; Protein Kinases; Tetradecanoylphorbol Acetate; Tyrosine | 1985 |
Stimulation by vasoactive intestinal polypeptide of catecholamine synthesis in isolated bovine adrenal chromaffin cells. Possible involvement of protein kinase C.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adrenal Medulla; Animals; Calcium; Carbachol; Catecholamines; Cattle; Colforsin; Dihydroxyphenylalanine; In Vitro Techniques; Isoquinolines; Piperazines; Tetradecanoylphorbol Acetate; Tyrosine; Vasoactive Intestinal Peptide | 1987 |
Pepsinogen secretion from perifused frog peptic glands: rapid transients detected with a modified pepsin assay.
Topics: Animals; Atropine; Carbachol; Esophagus; Hemoglobins; In Vitro Techniques; Mucous Membrane; Pepsin A; Pepsinogens; Perfusion; Rana catesbeiana; Tyrosine | 1988 |
Ascorbic acid specifically enhances dopamine beta-monooxygenase activity in resting and stimulated chromaffin cells.
Topics: Animals; Ascorbic Acid; Carbachol; Carbon Radioisotopes; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Dopamine; Dopamine beta-Hydroxylase; Kinetics; Norepinephrine; Stimulation, Chemical; Tyrosine | 1986 |
Role of protein kinase C in the synthesis of catecholamine by isolated bovine adrenal medullary cells.
Topics: Adrenal Medulla; Animals; Carbachol; Catecholamines; Cattle; Colforsin; In Vitro Techniques; Protein Kinase C; Tetradecanoylphorbol Acetate; Tyrosine | 1985 |
Bovine adrenal medulla: synthesis and secretion of radioactively labelled catecholamines and chromogranins.
Topics: Adrenal Glands; Adrenal Medulla; Animals; Carbachol; Catecholamines; Cattle; Chromaffin System; Chromatography, Thin Layer; Electrophoresis, Disc; Leucine; Protein Biosynthesis; Proteins; Time Factors; Tritium; Tyrosine | 1971 |
Changes in neostriatal DA metabolism after carbachol or atropine microinjections into the substantia nigra.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Atropine; Carbachol; Caudate Nucleus; Chromatography, Ion Exchange; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Hydrazines; Injections, Intravenous; Male; Methods; Microinjections; Rats; Substantia Nigra; Time Factors; Tritium; Tyrosine | 1974 |
The receptor-mediated activation of tyrosine hydroxylation in the superior cervical ganglion of the rat.
Topics: Aging; Animals; Bucladesine; Carbachol; Dopamine; Ganglia, Spinal; Hydroxylation; Kinetics; Pterins; Rats; Reserpine; Tyrosine | 1981 |
Trifluoperazine inhibits 45Ca2+ uptake and catecholamine secretion and synthesis in adrenal medullary cells.
Topics: Adrenal Medulla; Animals; Biological Transport, Active; Calcimycin; Calcium; Carbachol; Catecholamines; Cattle; Female; Kinetics; Potassium; Trifluoperazine; Tyrosine | 1983 |
The synthesis and release of [3H-tyrosine1]methionine5-enkephalin from guinea pig brain slices.
Topics: Animals; Atropine; Brain; Carbachol; Enkephalin, Methionine; Guinea Pigs; In Vitro Techniques; Kinetics; Potassium; Synaptosomes; Tritium; Tyrosine; Veratridine | 1983 |
A requirement for Syk in the activation of the microtubule-associated protein kinase/phospholipase A2 pathway by Fc epsilon R1 is not shared by a G protein-coupled receptor.
Topics: Animals; Antigens; Arachidonic Acid; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Cycle Proteins; Cell Line; Enzyme Activation; Enzyme Precursors; GTP-Binding Proteins; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Mast Cells; Phospholipases A; Phospholipases A2; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Rats; Receptor Aggregation; Receptors, IgE; Receptors, Muscarinic; Recombinant Proteins; Signal Transduction; Swine; Syk Kinase; Transfection; Tyrosine | 1995 |
Carbachol, substance P, and phorbol ester promote the tyrosine phosphorylation of protein kinase C delta in salivary gland epithelial cells.
Topics: Alkaloids; Animals; Biological Transport; Carbachol; Cell Membrane; Cells, Cultured; Enzyme Activation; Epithelial Cells; Epithelium; ErbB Receptors; Genistein; Isoenzymes; Isoflavones; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Rats; Receptor, Insulin; Salivary Glands; Staurosporine; Substance P; Tetradecanoylphorbol Acetate; Tyrosine | 1995 |
Tumor-suppressor function of muscarinic acetylcholine receptors is associated with activation of receptor-operated calcium influx.
Topics: Animals; Calcium; Calcium Channels; Carbachol; CHO Cells; Cricetinae; Female; In Vitro Techniques; Ion Channel Gating; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Phosphoproteins; Phosphotyrosine; Rats; Receptors, Muscarinic; Second Messenger Systems; Transfection; Tumor Cells, Cultured; Tyrosine | 1993 |
Muscarinic receptor-mediated tyrosine phosphorylation of phospholipase C-gamma. An alternative mechanism for cholinergic-induced phosphoinositide breakdown.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; CHO Cells; Cricetinae; Isoenzymes; Kinetics; Marine Toxins; Oxocins; Phosphatidylinositols; Phosphorylation; Phosphotyrosine; Receptors, Muscarinic; Transfection; Type C Phospholipases; Tyrosine | 1993 |
Stimulation of tyrosine phosphorylation and mitogen-activated-protein (MAP) kinase activity in human SH-SY5Y neuroblastoma cells by carbachol.
Topics: Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Enzyme Activation; Epidermal Growth Factor; Humans; Neuroblastoma; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Kinases; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1993 |
Tyrosine phosphorylation of a mitogen-activated protein kinase-like protein occurs at a late step in exocytosis. Studies with tyrosine phosphatase inhibitors and various secretagogues in rat RBL-2H3 cells.
Topics: Actins; Animals; Arachidonic Acid; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Electrophoresis, Polyacrylamide Gel; Exocytosis; Hexosaminidases; Hydrogen Peroxide; Inositol Phosphates; Kinetics; Leukemia, Basophilic, Acute; Phospholipids; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Tumor Cells, Cultured; Tyrosine; Vanadates | 1993 |
Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor.
Topics: Alkaloids; Amyloid; Carbachol; Cell Line; Genistein; Humans; Isoflavones; Phosphorylation; Prion Proteins; Prions; Protein Kinase Inhibitors; Protein Precursors; Protein Tyrosine Phosphatases; Receptors, Muscarinic; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Protection by alcuronium of muscarinic receptors against chemical inactivation and location of the allosteric binding site for alcuronium.
Topics: Acetylcholine; Alcuronium; Allosteric Site; Animals; Aspartic Acid; Atropine; Carbachol; Choline; Cholinergic Agents; Female; Gallamine Triethiodide; Glutamic Acid; Heart Atria; Male; Parasympatholytics; Rats; Rats, Wistar; Receptors, Muscarinic; Tyrosine | 1994 |
Mechanisms of phospholipase D stimulation by m3 muscarinic acetylcholine receptors. Evidence for involvement of tyrosine phosphorylation.
Topics: Acetylcholine; Calcium; Carbachol; Cell Line; Cells, Cultured; Enzyme Activation; Humans; Kidney; Phospholipase D; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tyrosine | 1994 |
Hormonal regulation of MAP kinase in cultured rat inner medullary collecting tubule cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Polarity; Cells, Cultured; Enzyme Activation; Epidermal Growth Factor; Hormones; Kidney Medulla; Kidney Tubules, Collecting; Muscarine; Peptides; Phosphorylation; Purines; Rats; Tyrosine; Vasopressins | 1994 |
Conserved tyrosines in the alpha subunit of the nicotinic acetylcholine receptor stabilize quaternary ammonium groups of agonists and curariform antagonists.
Topics: Animals; Carbachol; Kinetics; Ligands; Mice; Mutagenesis, Site-Directed; Nicotinic Antagonists; Parasympatholytics; Parasympathomimetics; Protein Binding; Quaternary Ammonium Compounds; Receptors, Nicotinic; Structure-Activity Relationship; Tubocurarine; Tyrosine | 1994 |
Functional role of a cytoplasmic aromatic amino acid in muscarinic receptor-mediated activation of phospholipase C.
Topics: Amino Acid Sequence; Animals; Carbachol; Cell Line; Chlorocebus aethiops; Cytoplasm; Enzyme Activation; GTP-Binding Proteins; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Phosphatidylinositols; Protein Conformation; Protein Structure, Secondary; Rats; Receptors, Muscarinic; Restriction Mapping; Scopolamine Derivatives; Transfection; Type C Phospholipases; Tyrosine | 1994 |
Differential role of the carboxyl-terminal tyrosine in down-regulation and sequestration of the m2 muscarinic acetylcholine receptor.
Topics: Amino Acid Sequence; Animals; beta-Galactosidase; Carbachol; Cell Line; Cell Membrane; Choriocarcinoma; Cyclic AMP; Down-Regulation; Female; Humans; Kinetics; Luciferases; Mammals; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Pregnancy; Quinuclidinyl Benzilate; Receptors, Adrenergic, beta-2; Receptors, Muscarinic; Scopolamine Derivatives; Sequence Homology, Amino Acid; Transfection; Tumor Cells, Cultured; Tyrosine; Uterine Neoplasms | 1994 |
Activation kinetics of recombinant mouse nicotinic acetylcholine receptors: mutations of alpha-subunit tyrosine 190 affect both binding and gating.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Binding Sites; Carbachol; Ion Channel Gating; Kinetics; Macromolecular Substances; Mathematics; Membrane Potentials; Mice; Models, Theoretical; Mutagenesis, Site-Directed; Point Mutation; Quaternary Ammonium Compounds; Receptors, Nicotinic; Recombinant Proteins; Tyrosine | 1995 |
Effect of genistein on amylase release and protein tyrosine phosphorylation in parotid acinar cells.
Topics: Amylases; Animals; Bucladesine; Carbachol; Cyclic AMP; Enzyme Inhibitors; Exocytosis; Genistein; Isoflavones; Isoproterenol; Parotid Gland; Phosphorylation; Protein-Tyrosine Kinases; Rats; Thionucleotides; Tyrosine | 1996 |
Amino acid side chains that define muscarinic receptor/G-protein coupling. Studies of the third intracellular loop.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Arginine; Carbachol; Cloning, Molecular; Conserved Sequence; GTP-Binding Proteins; Isoleucine; Kinetics; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Protein Structure, Secondary; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Structure-Activity Relationship; Threonine; Transfection; Tyrosine | 1996 |
Role of two highly conserved tyrosine residues in the m1 muscarinic receptor second transmembrane domain in ligand binding and receptor function.
Topics: Animals; Binding Sites; Carbachol; CHO Cells; Conserved Sequence; Cricetinae; Hydrolysis; Ligands; Molecular Structure; Mutagenesis, Site-Directed; N-Methylscopolamine; Phosphatidylinositols; Radioligand Assay; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Scopolamine Derivatives; Tyrosine | 1996 |
Implication of Ca(2+)-dependent protein tyrosine phosphorylation in carbachol-induced phospholipase D activation in rat pheochromocytoma PC12 cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Calcium; Carbachol; Enzyme Activation; PC12 Cells; Phospholipase D; Phosphorylation; Proteins; Rats; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Tyrosine | 1997 |
Linkage of G protein-coupled receptors to the MAPK signaling pathway through PI 3-kinase gamma.
Topics: Adaptor Proteins, Signal Transducing; Androstadienes; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Membrane; COS Cells; Enzyme Activation; GRB2 Adaptor Protein; GTP-Binding Proteins; Guanine Nucleotide Exchange Factors; Mitogen-Activated Protein Kinase 1; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Proteins; ras Guanine Nucleotide Exchange Factors; ras Proteins; Receptor Protein-Tyrosine Kinases; Receptor, Muscarinic M2; Receptors, Muscarinic; Recombinant Fusion Proteins; Signal Transduction; Transfection; Tyrosine; Wortmannin | 1997 |
Elevated intracellular calcium concentration increases secretory processing of the amyloid precursor protein by a tyrosine phosphorylation-dependent mechanism.
Topics: Amyloid beta-Protein Precursor; Blotting, Western; Calcium; Carbachol; Cells, Cultured; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Genistein; Humans; Indoles; Ionomycin; Isoflavones; Kidney; Maleimides; Phosphorylation; Phosphotyrosine; Protein Kinase C; Receptors, Muscarinic; Signal Transduction; Tyrosine | 1996 |
Interactions of the nicotinic acetylcholine receptor transmembrane segments with the lipid bilayer in native receptor-rich membranes.
Topics: Animals; Binding Sites; Carbachol; Cell Membrane; Cholesterol; Electric Organ; Electron Spin Resonance Spectroscopy; Endopeptidase K; In Vitro Techniques; Ion Channels; Lipid Bilayers; Phospholipids; Phosphorylation; Receptors, Nicotinic; Signal Transduction; Spin Labels; Torpedo; Tyrosine | 1997 |
Regulation of cellular tyrosine phosphorylation by stimulatory and inhibitory muscarinic acetylcholine receptors.
Topics: Animals; Calcium Channel Blockers; Carbachol; CHO Cells; Cricetinae; Immunoblotting; Immunohistochemistry; Isoenzymes; Microscopy, Electron; Muscarinic Agonists; Phospholipase C gamma; Phosphorylation; Receptors, Muscarinic; Signal Transduction; Triazoles; Type C Phospholipases; Tyrosine | 1997 |
Tyrosine phosphorylation in contraction of opossum esophageal longitudinal muscle in response to SNP.
Topics: Animals; Benzylidene Compounds; Carbachol; Cyclic GMP; Enzyme Inhibitors; Genistein; Isoflavones; Isometric Contraction; Models, Biological; Muscle Relaxation; Muscle, Smooth; Nitriles; Nitroprusside; Opossums; Phosphorylation; Phosphotyrosine; Potassium Chloride; Protein-Tyrosine Kinases; Trachea; Tyrosine; Tyrphostins | 1997 |
Site-directed mutagenesis on the m2 muscarinic acetylcholine receptor: the significance of Tyr403 in the binding of agonists and functional coupling.
Topics: Acetylcholine; Animals; Binding Sites; Carbachol; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; Mutagenesis, Site-Directed; Mutation; Oxotremorine; Receptor, Muscarinic M2; Receptors, Muscarinic; Tyrosine | 1997 |
Distinctions in agonist and antagonist specificity conferred by anionic residues of the nicotinic acetylcholine receptor.
Topics: Amino Acid Sequence; Binding Sites; Carbachol; Cell Line; Choline; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Nicotinic Agonists; Nicotinic Antagonists; Proadifen; Receptors, Nicotinic; Sequence Alignment; Tubocurarine; Tyrosine | 1998 |
Involvement of protein kinases and phosphatases in tyrosine phosphorylation of PKCdelta in rat parotid acinar cells exposed to secretory stimuli.
Topics: Animals; Carbachol; Carcinogens; Enzyme Inhibitors; Epithelial Cells; Genistein; Isoenzymes; Muscarinic Agonists; Parotid Gland; Phosphoprotein Phosphatases; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Rats; Staurosporine; Substance P; Tetradecanoylphorbol Acetate; Tyrosine | 1998 |
Functional muscarinic m3 receptor expressed in gastric cancer cells stimulates tyrosine phosphorylation and MAP kinase.
Topics: Atropine; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Densitometry; Dose-Response Relationship, Drug; Humans; Intracellular Fluid; Naphthalenes; Phosphorylation; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stomach Neoplasms; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1999 |
Carbachol activates ERK2 in isolated gastric parietal cells via multiple signaling pathways.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cells, Cultured; Dogs; Enzyme Activation; Epidermal Growth Factor; Gene Expression Regulation; Genes, Dominant; GRB2 Adaptor Protein; Membrane Proteins; Mitogen-Activated Protein Kinase 1; Parietal Cells, Gastric; Phosphorylation; Proteins; ras Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; Son of Sevenless Proteins; Transfection; Tyrosine | 1999 |
Local anesthetics inhibit muscarinic receptor-mediated activation of extracellular signal-regulated kinases in rat pheochromocytoma PC12 cells.
Topics: Anesthetics, Local; Animals; Carbachol; Enzyme Activation; Enzyme Inhibitors; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscarinic Agonists; Muscarinic Antagonists; PC12 Cells; Phosphoprotein Phosphatases; Phosphorylation; Procaine; Rats; Receptors, Muscarinic; Tetradecanoylphorbol Acetate; Tetrodotoxin; Tyrosine | 1999 |
ErbB2 and ErbB3 receptors mediate inhibition of calcium-dependent chloride secretion in colonic epithelial cells.
Topics: Calcium; Carbachol; Cells, Cultured; Chlorides; Colon; Diphtheria Toxin; Humans; Intestinal Mucosa; Neuregulin-1; Phosphatidylinositol 3-Kinases; Phosphorylation; Receptor, ErbB-2; Recombinant Fusion Proteins; Single-Chain Antibodies; Tyrosine | 1999 |
Interleukin (IL)-7 induces rapid activation of Pyk2, which is bound to Janus kinase 1 and IL-7Ralpha.
Topics: Animals; Calcium; Carbachol; Cell Adhesion Molecules; Cell Survival; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Interleukin-7; JNK Mitogen-Activated Protein Kinases; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Interleukin-7; Tyrosine | 2000 |
A role for phosphoinositides in tyrosine phosphorylation of p125 focal adhesion kinase in rat pancreatic acini.
Topics: Animals; Blotting, Western; Calcium; Carbachol; Cell Adhesion Molecules; Crk-Associated Substrate Protein; Cytoskeletal Proteins; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Male; Pancreas; Paxillin; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Rats; Rats, Wistar; Retinoblastoma-Like Protein p130; Sincalide; Tyrosine | 2000 |
Agonist-dependent difference in the mechanisms involved in Ca2+ sensitization of smooth muscle of porcine coronary artery.
Topics: Animals; Calcium; Calcium Signaling; Carbachol; Cardiotonic Agents; Coronary Vessels; Endothelin-1; In Vitro Techniques; Mesenteric Arteries; Muscle, Smooth, Vascular; Phosphorylation; Protein Kinase C; Rabbits; rho GTP-Binding Proteins; Swine; Tyrosine | 2000 |
Potentiation of carbachol-induced Ca2+ release by peroxynitrite in human neuroblastoma SH-SY5Y cells.
Topics: Calcium; Carbachol; Genistein; Humans; Molsidomine; Neuroblastoma; Nitrates; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 2000 |
Phospholipase C-gamma mediates the hydrolysis of phosphatidylinositol, but not of phosphatidylinositol 4,5-bisphoshate, in carbamylcholine-stimulated islets of langerhans.
Topics: Adenoviridae; Androstadienes; Animals; Carbachol; Cholinergic Agonists; Chromatography, High Pressure Liquid; Chromones; Enzyme Inhibitors; Genistein; Hydrolysis; Inositol Phosphates; Islets of Langerhans; Isoenzymes; Membrane Potentials; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Rats; Signal Transduction; Time Factors; Type C Phospholipases; Tyrosine; Vanadates; Wortmannin | 2001 |
Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases.
Topics: Animals; Calcium; Carbachol; Carcinogens; Cholinergic Agents; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Estrenes; Isoenzymes; Male; Neurons; Parotid Gland; PC12 Cells; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; src-Family Kinases; Substance P; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates | 2001 |
Insulin and IGF-I inhibit calcium-dependent chloride secretion by T84 human colonic epithelial cells.
Topics: Androstadienes; Carbachol; Cells, Cultured; Chlorides; Cholinergic Agonists; Chromones; Colon; Diabetes Mellitus; Diarrhea; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Insulin; Insulin-Like Growth Factor I; Intestinal Mucosa; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Thapsigargin; Tyrosine; Wortmannin | 2001 |
Src family kinase involvement in muscarinic receptor-induced tyrosine phosphorylation in differentiated SH-SY5Y cells.
Topics: Carbachol; Cell Differentiation; Cellular Apoptosis Susceptibility Protein; Cholinergic Agonists; Cytoskeletal Proteins; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Neurons; Paxillin; Phenotype; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Receptors, Muscarinic; Signal Transduction; src-Family Kinases; Tumor Cells, Cultured; Tyrosine | 2001 |
Effect of calmodulin antagonists on phospholipase D activity in SH-SY5Y cells.
Topics: Calmodulin; Carbachol; Cell Line; Cholinergic Agonists; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glycerophospholipids; Imidazoles; Phosphatidic Acids; Phospholipase D; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Trifluoperazine; Tyrosine | 2002 |
Differential tyrosine phosphorylation of plasma membrane Ca2+-ATPase and regulation of calcium pump activity by carbachol and bradykinin.
Topics: Bradykinin; Calcium; Calcium-Transporting ATPases; Carbachol; Cell Line; Cell Membrane; Humans; Kinetics; Phosphorylation; Thapsigargin; Tyrosine | 2003 |
Glucose stimulates the tyrosine phosphorylation of Crk-associated substrate in pancreatic beta-cells.
Topics: Adaptor Proteins, Signal Transducing; Animals; Blotting, Western; Carbachol; Cell Line; Cells, Cultured; Cytoskeleton; Dose-Response Relationship, Drug; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glucose; Immunoglobulin G; Islets of Langerhans; Mass Spectrometry; Peptides; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Conformation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; src Homology Domains; Time Factors; Tyrosine | 2003 |
Growth hormone reduces chloride secretion in human colonic epithelial cells via EGF receptor and extracellular regulated kinase.
Topics: Biological Transport; Carbachol; Cell Line; Chlorides; Cholinergic Agonists; Enzyme Inhibitors; Epithelial Cells; ErbB Receptors; Flavonoids; Human Growth Hormone; Humans; Imidazoles; Intestinal Mucosa; Janus Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pyridines; Tyrosine | 2003 |
Identification of nicotinic acetylcholine receptor amino acids photolabeled by the volatile anesthetic halothane.
Topics: Amino Acid Sequence; Anesthetics, Inhalation; Animals; Binding Sites; Binding, Competitive; Carbachol; Carbon Radioisotopes; Halothane; Isoflurane; Models, Molecular; Molecular Sequence Data; Peptide Fragments; Photoaffinity Labels; Protein Subunits; Receptors, Nicotinic; Sequence Analysis, Protein; Sodium-Potassium-Exchanging ATPase; Torpedo; Tryptophan; Tubocurarine; Tyrosine | 2003 |
Galphaq/11 signaling induces apoptosis through two pathways involving reduction of Akt phosphorylation and activation of RhoA in HeLa cells.
Topics: Apoptosis; Carbachol; Cholinergic Agonists; Down-Regulation; Enzyme Inhibitors; GTP-Binding Protein alpha Subunits, Gq-G11; HeLa Cells; Humans; Insulin; Insulin Receptor Substrate Proteins; Intracellular Signaling Peptides and Proteins; Mitochondria; Mutation; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Receptor, Muscarinic M1; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Tyrosine | 2004 |
Transactivation of the epidermal growth factor receptor mediates muscarinic stimulation of focal adhesion kinase in intestinal epithelial cells.
Topics: Actin Cytoskeleton; Calcium; Carbachol; Cell Line; Epithelial Cells; ErbB Receptors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Intestinal Mucosa; Muscarinic Agonists; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; Tyrosine | 2005 |
Functionality of nitrated acetylcholine receptor: the two-step formation of nitrotyrosines reveals their differential role in effectors binding.
Topics: Acetylcholine; Animals; Autoradiography; Binding Sites; Binding, Competitive; Bungarotoxins; Carbachol; Carbon Radioisotopes; Cell Membrane; Dose-Response Relationship, Drug; Iodine Radioisotopes; Kinetics; Nicotinic Agonists; Protein Binding; Receptors, Nicotinic; Spectrophotometry; Tetranitromethane; Torpedo; Tubocurarine; Tyrosine | 2005 |
The role of tyrosine kinase in prostaglandin E2 and vanadate-evoked contractions in rabbit duodenum in vitro.
Topics: Animals; Calcium; Carbachol; Dinoprostone; Dose-Response Relationship, Drug; Duodenum; Estrenes; Genistein; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Phosphorylation; Protein-Tyrosine Kinases; Pyrrolidinones; Rabbits; Tyrosine; Tyrphostins; Vanadates; Verapamil | 2006 |
Differential FAK phosphorylation at Ser-910, Ser-843 and Tyr-397 induced by angiotensin II, LPA and EGF in intestinal epithelial cells.
Topics: Angiotensins; Animals; Carbachol; Cell Line; Epidermal Growth Factor; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Humans; Intestinal Mucosa; Ionomycin; Kinetics; Lysophospholipids; Phosphorylation; Protein Kinase C; Rats; Receptors, G-Protein-Coupled; Serine; Signal Transduction; Tyrosine | 2007 |
The effect of partial bladder outlet obstruction on carbonyl and nitrotyrosine distribution in rabbit bladder.
Topics: Animals; Carbachol; Electric Stimulation; In Vitro Techniques; Male; Mucous Membrane; Muscle Contraction; Organ Size; Protein Carbonylation; Rabbits; Reactive Nitrogen Species; Reactive Oxygen Species; Tyrosine; Urinary Bladder; Urinary Bladder Neck Obstruction | 2007 |
The immediate effect of nitric oxide on the rabbit bladder after ovariectomy.
Topics: Analysis of Variance; Animals; Arginine; Blotting, Western; Carbachol; Female; Free Radicals; Isometric Contraction; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ovariectomy; Oxidative Stress; Potassium Chloride; Protein Carbonylation; Rabbits; Reperfusion Injury; Tyrosine; Urinary Bladder; Urination | 2008 |
Estrogen administration attenuates bladder outlet obstruction induced oxidative stress in the female rabbit.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Carbachol; Choline O-Acetyltransferase; Cholinergic Agonists; Disease Models, Animal; Drug Administration Schedule; Electric Stimulation; Estradiol; Estrogens; Female; Injections, Subcutaneous; Muscle Contraction; Oxidative Stress; Potassium Chloride; Protein Carbonylation; Rabbits; Superoxide Dismutase; Tyrosine; Urinary Bladder; Urinary Bladder Neck Obstruction | 2009 |
Comparison of the activation kinetics of the M3 acetylcholine receptor and a constitutively active mutant receptor in living cells.
Topics: Acetylcholine; Asparagine; Carbachol; Dose-Response Relationship, Drug; HEK293 Cells; Humans; Point Mutation; Protein Binding; Receptor, Muscarinic M3; Tyrosine | 2012 |
Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR).
Topics: Animals; Benzoates; Calcium; Carbachol; Cell Line; Cholinergic Agonists; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cystic Fibrosis Transmembrane Conductance Regulator; Enzyme Inhibitors; Focal Adhesion Kinase 2; Humans; Immunoblotting; Membrane Potentials; Mutation; Patch-Clamp Techniques; Phosphorylation; Protein Phosphatase 2; Receptor, Muscarinic M3; Signal Transduction; src-Family Kinases; Thiazolidines; Thionucleotides; Tyrosine | 2013 |