carbachol has been researched along with quinuclidines in 65 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 30 (46.15) | 18.7374 |
| 1990's | 14 (21.54) | 18.2507 |
| 2000's | 17 (26.15) | 29.6817 |
| 2010's | 3 (4.62) | 24.3611 |
| 2020's | 1 (1.54) | 2.80 |
| Authors | Studies |
|---|---|
| Lamble, AP; Lamble, JW | 1 |
| Gray, DB; Lane, MA; Sastre, A | 1 |
| Birdsall, NJ; Burgen, AS; Strange, PG | 1 |
| François, J; Goes, F | 1 |
| Ober, M; Scharrer, A | 1 |
| Maayani, S; Sokolovsky, M; Treister, G | 1 |
| Galper, JB; Smith, TW | 1 |
| Aronstam, RS; Eldefrawi, ME | 1 |
| Catterall, WA; Galper, JB; Klein, W | 1 |
| Carson, S; Godwin, S; Kato, G; Massoulié, J | 1 |
| Abood, LG; Aronstam, RS; Kellogg, C | 1 |
| Abood, LG; Aronstam, R; Baumgold, J | 1 |
| Ehlert, FJ; Kokka, N | 1 |
| Bhattacharya, SK; Das Gupta, G; Sen, AP; Seth, K; Seth, PK | 1 |
| Abreu, M; Audia, VH; Kachur, JF; Kaiser, C; McPherson, DW; Rzeszotarski, WJ; Sturm, B; Weitzberg, M | 1 |
| Dwyer, TM; Farley, JM; Ho, IK; Mohan, PM; Yang, CM | 1 |
| Brotcke, TP; Longhurst, PA | 1 |
| Choo, LK; Mitchelson, FJ | 1 |
| Adem, A; Nordberg, A; Sabbagh, M | 1 |
| Roeske, WR; Watson, M; Yamamura, HI | 1 |
| Bering, B; Müller, WE | 1 |
| Bloom, JW; Halonen, M; Lawrence, LJ; Rould, E; Seaver, NA; Yamamura, HI | 1 |
| Dwyer, TM; Farley, JM; Yang, CM | 1 |
| Ravikumar, BV; Sastry, PS | 1 |
| Snyder, SH; Yamamura, HI | 1 |
| Holland, MG | 1 |
| Samoĭlovich, IM | 1 |
| Merkle, W | 1 |
| Ciracì, G; Giummarra, C; Reibaldi, A | 1 |
| Asselin, J; Dumont, Y; Larose, L; Morisset, J; Poirier, GG | 1 |
| Salvaterra, PM | 1 |
| Dziekan, LC; Galper, JB; O'Hara, DS; Smith, TW | 1 |
| McNamara, JO; Savage, DD | 1 |
| Barg, J; Danenberg, HD; Gurwitz, D; Haring, R; Heldman, E; Marciano, D; Meshulam, H; Pinkas-Kramarski, R; Pittel, Z; Wengier, A | 1 |
| Gabelt, BT; Kaufman, PL; Poyer, JF | 1 |
| Fisher, A; Gurwitz, D; Haring, R; Heldman, E; Karton, Y; Pinkas-Kramarski, R; Stein, R | 1 |
| Barg, J; Gurwitz, D; Haring, R; Heldman, E; Karton, Y; Marciano, D; Meshulam, H; Pinkas-Kramarski, R; Pittel, Z; Wengier, A | 1 |
| Costa, E; de Erausquin, G; Fohrman, EB; Wojcik, WJ | 1 |
| Flügel, C; Kaufman, PL; Poyer, JF | 1 |
| Fisher, A; Fraser, CM; Gurwitz, D; Haring, R; Heldman, E; Manor, D | 1 |
| Barg, J; Behar, L; Fisher, A; Ginzburg, I; Gurwitz, D; Sadot, E | 1 |
| Hubbard, WC; Kaufman, PL; Kee, C | 1 |
| Brown, AM; Hunter, AJ; Middlemiss, DN; Watson, JM | 1 |
| Mustafa, S; Oriowo, MA | 1 |
| Kouznetsova, M; Nistri, A | 1 |
| Erickson, KA; Schroeder, A | 1 |
| Cohen, ML; Stengel, PW | 1 |
| Furness, JB; Kumano, K; Kunze, WA; Larsson, H; Murr, E; Vogalis, F | 1 |
| Honda, K; Ikeda, K; Kobayashi, S; Miyata, K; Suzuki, M; Takeuchi, M; Yamada, T | 1 |
| Holden, JE; Thomas, S; Van Poppel, AY | 1 |
| Iida, H; Inoue, N; Ishida, H; Ishikawa, Y; Yuan, Z | 1 |
| Ikeda, K; Kobayashi, S; Miyata, K | 1 |
| Chen, HZ; Cui, YY; Feng, JM; Wu, XJ; Zhu, L | 1 |
| Hatanaka, T; Miyata, K; Noguchi, Y; Ohtake, A; Okutsu, H; Saitoh, C; Sasamata, M; Sato, S; Suzuki, M; Ukai, M; Yuyama, H | 1 |
| Ehlert, FJ; Figueroa, KW; Griffin, MT; Liller, S | 1 |
| Chugh, A; Gupta, JB; Hegde, LG; Kumar, N; Meru, AV; Naruganahalli, KS; Ray, A; Sinha, S | 1 |
| Noguchi, Y; Ohtake, A; Okutsu, H; Sasamata, M; Sato, S; Suzuki, M | 1 |
| Inadome, A; Maeda, Y; Masunaga, K; Murakami, S; Satoji, Y; Sugiyama, Y; Ueda, S; Yoshida, M | 1 |
| Holden, JE; Pizzi, JA | 1 |
| Atorino, G; Aviello, G; Borrelli, F; Capasso, R; Pagano, E; Romano, B | 1 |
| Holden, JE; Jeong, Y; Pizzi, JA | 1 |
| Amari, G; Bassani, F; Battipaglia, L; Bergamaschi, M; Berti, F; Bolzoni, PT; Cacciani, F; Cenacchi, V; Civelli, M; Delcanale, M; Geppetti, PA; Harrison, S; Mannini, F; Pastore, F; Patacchini, R; Petrillo, P; Razzetti, R; Rizzi, A; Rossoni, G; Santoro, E; Scudellaro, R; Villetti, G; Volta, R; Zaniboni, M | 1 |
| Chess-Williams, R; Moro, C; Uchiyama, J | 1 |
| Barrett, VJ; Buckley, PT; Burman, M; DeHaas, CJ; Foley, JJ; Hay, DW; Kotzer, CJ; Lainé, DI; Luttmann, MA; Palovich, MR; Rumsey, WL; Salmon, M; Sarau, HM; Schmidt, DB; Slack, RJ; Webb, EF | 1 |
| Isola, M; Isola, R; Loy, F; Masala, C | 1 |
1 review(s) available for carbachol and quinuclidines
| Article | Year |
|---|---|
Autonomic drugs in ophthalmology: some problems and promises. I. Directly and indirectly acting parasympathomimetic drugs.
Topics: Administration, Topical; Animals; Carbachol; Cataract; Cholinesterase Inhibitors; Contact Lenses, Hydrophilic; Echothiophate Iodide; Eye; Eye Diseases; Glaucoma; Haplorhini; Humans; Intraocular Pressure; Isoflurophate; Parasympathomimetics; Pharmaceutical Vehicles; Pilocarpine; Pralidoxime Compounds; Quaternary Ammonium Compounds; Quinuclidines; Rabbits | 1974 |
64 other study(ies) available for carbachol and quinuclidines
| Article | Year |
|---|---|
The effect of miotics on the intraocular pressure of conscious owl monkeys.
Topics: Anesthesia, Local; Animals; Aotus trivirgatus; Carbachol; Dose-Response Relationship, Drug; Haplorhini; Intraocular Pressure; Male; Miotics; Oxotremorine; Parasympathomimetics; Pilocarpine; Quinuclidines; Spiro Compounds; Succinimides; Tonometry, Ocular | 1976 |
Muscarinic cholinergic binding sites in the developing avian heart.
Topics: Acetylcholine; Animals; Atropine; Benzyl Compounds; Carbachol; Chick Embryo; Heart; Methacholine Compounds; Microsomes; Myocardium; Nicotine; Oxotremorine; Physostigmine; Quaternary Ammonium Compounds; Quinuclidines; Receptors, Cholinergic; Scopolamine; Snake Venoms; Tubocurarine | 1977 |
Occupancy of muscarinic acetylcholine receptors stimulates a guanylate cyclase in neuroblastoma cells.
Topics: Acetylcholine; Atropine; Carbachol; Cell Line; Cell Membrane; Enzyme Activation; Guanylate Cyclase; Kinetics; Neuroblastoma; Oxotremorine; Pilocarpine; Quinuclidines; Receptors, Cholinergic; Receptors, Muscarinic | 1977 |
Ultrasonographic study of the effect of different miotics on the eye components.
Topics: Administration, Topical; Adult; Anterior Chamber; Carbachol; Epinephrine; Eye; Humans; Lens, Crystalline; Middle Aged; Miotics; Myopia; Pain; Pilocarpine; Pupil; Quinuclidines; Refraction, Ocular; Ultrasonography; Vitreous Body | 1977 |
[The effect of timolol and parasympathicomimetica in the treatment of the elevated intraocular pressure (author's transl)].
Topics: Carbachol; Drug Administration Schedule; Glaucoma; Humans; Intraocular Pressure; Parasympathomimetics; Pilocarpine; Propanolamines; Quinuclidines; Timolol | 1979 |
Drugs affecting the cholinergic system in the intact mammalian eye. I. Evaluation of the miotic activity of acetylcholine-like drugs in the mouse eye.
Topics: Acetylcholine; Animals; Arecoline; Carbachol; Guinea Pigs; Hydrogen-Ion Concentration; Miotics; Oxotremorine; Phencyclidine; Pupil; Quinuclidines | 1975 |
Properties of muscarinic acetylcholine receptors in heart cell cultures.
Topics: Animals; Binding, Competitive; Carbachol; Cells, Cultured; Chick Embryo; Kinetics; Myocardial Contraction; Parasympathomimetics; Quinuclidines; Receptors, Cholinergic; Receptors, Muscarinic | 1978 |
Reversible conversion between affinity states for agonists of the muscarinic acetylcholine receptor from rat brain.
Topics: Acetylcholine; Alkylation; Animals; Brain; Carbachol; Cyanides; Dithiothreitol; In Vitro Techniques; Male; Membranes; Quinuclidines; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Sulfhydryl Compounds | 1979 |
Muscarinic acetylcholine receptors in developing chick heart.
Topics: Acetylcholine; Animals; Binding, Competitive; Carbachol; Chick Embryo; Heart; Heart Rate; Kinetics; Myocardium; Quinuclidines; Receptors, Cholinergic; Receptors, Muscarinic; Time Factors | 1977 |
Biochemical studies on muscarinic receptors.
Topics: Acetylcholine; Alkylating Agents; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Cattle; Choline; Dexetimide; Kinetics; Ligands; Muscle Contraction; Muscle, Smooth; Quinuclidines; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Solubility; Subcellular Fractions | 1977 |
Development of muscarinic cholinergic receptors in inbred strains of mice: identification of receptor heterogeneity and relation to audiogenic seizure susceptibility.
Topics: Acoustic Stimulation; Aging; Animals; Animals, Newborn; Brain; Brain Stem; Carbachol; Cerebral Cortex; Corpus Striatum; Hypothalamus; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Quinuclidines; Receptors, Cholinergic; Receptors, Muscarinic; Seizures; Thalamus | 1979 |
Studies on the relationship of binding affinity to psychoactive and anticholingergic potency of a group of psychotomimetic glycolates.
Topics: Animals; Arecoline; Atropine; Binding Sites; Binding, Competitive; Brain; Carbachol; Chemical Phenomena; Chemistry; Dose-Response Relationship, Drug; Glycolates; Hallucinogens; Kinetics; Male; Parasympatholytics; Phosphatidylserines; Quinuclidines; Rats; Receptors, Drug; Scopolamine; Stereoisomerism; Structure-Activity Relationship | 1977 |
Decrease in (3H)-quinuclidinyl bezilate binding to the muscarinic cholinergic receptor in the longitudinal muscle of the rat ileum following chronic administration of diisopropylfuorophosphate.
Topics: Acetylcholine; Animals; Binding, Competitive; Carbachol; Cholinesterases; Depression, Chemical; Ileum; In Vitro Techniques; Isoflurophate; Male; Muscle, Smooth; Myocardium; Oxotremorine; Quinuclidines; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Time Factors | 1977 |
Central muscarinic receptor subtypes and carrageenin-induced paw oedema in rats.
Topics: Animals; Arecoline; Carbachol; Carrageenan; Cerebellum; Corpus Striatum; Edema; Female; Foot; Gallamine Triethiodide; Inflammation; Male; Oxotremorine; Pirenzepine; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1991 |
Synthesis of some 3-(1-azabicyclo[2.2.2]octyl) 3-amino-2-hydroxy-2-phenylpropionates: profile of antimuscarinic efficacy and selectivity.
Topics: Animals; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Lactates; Male; Molecular Structure; Muscle Contraction; Myocardial Contraction; Parasympatholytics; Phenylpropionates; Quinuclidines; Quinuclidinyl Benzilate; Rabbits; Rats; Receptors, Muscarinic; Vas Deferens | 1990 |
Down-regulation of muscarinic receptors in the striatum of organophosphate-treated swine.
Topics: Acetylcholinesterase; Animals; Binding Sites; Binding, Competitive; Carbachol; Corpus Striatum; Down-Regulation; Guanylyl Imidodiphosphate; Isoflurophate; Magnesium; Male; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Receptors, Muscarinic; Regression Analysis; Swine | 1990 |
Effects of castration and diabetes mellitus on cholinergic responsiveness and muscarinic receptors in the rat vas deferens.
Topics: Animals; Atropine; Binding Sites; Carbachol; Diabetes Mellitus, Experimental; Male; Muscle Contraction; Muscle, Smooth; Orchiectomy; Potassium Chloride; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred BB; Rats, Inbred Strains; Receptors, Muscarinic; Vas Deferens | 1989 |
Comparison of the affinity constant of some muscarinic receptor antagonists with their displacement of [3H]quinuclidinyl benzilate binding in atrial and ileal longitudinal muscle of the guinea-pig.
Topics: Animals; Binding, Competitive; Carbachol; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Myocardial Contraction; Myocardium; Parasympatholytics; Quinuclidines; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1985 |
Characterization of agonist and antagonist binding to muscarinic cholinergic receptors solubilized from rat cerebral cortex.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; In Vitro Techniques; Male; Oxotremorine; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
[3H]pirenzepine and (-)-[3H]quinuclidinyl benzilate binding to rat cerebral cortical and cardiac muscarinic cholinergic sites. I. Characterization and regulation of agonist binding to putative muscarinic subtypes.
Topics: Acetylcholine; Animals; Benzodiazepinones; Buffers; Carbachol; Cerebral Cortex; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Myocardium; Parasympathomimetics; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tritium | 1986 |
Stereospecific 3H-QNB binding to human erythrocyte membranes associated with muscarinic cholinergic receptors.
Topics: Adult; Aging; Animals; Atropine; Brain; Carbachol; Erythrocyte Membrane; Female; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Male; Middle Aged; Myocardium; Oxotremorine; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stereoisomerism | 1987 |
Characterization of high affinity [3H]pirenzepine and (-)-[3H] quinuclidinyl benzilate binding to muscarinic cholinergic receptors in rabbit peripheral lung.
Topics: Animals; Binding, Competitive; Carbachol; Female; Guanylyl Imidodiphosphate; Kinetics; Lung; Male; Myocardium; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Stereoisomerism | 1987 |
Biochemical characteristics of muscarinic cholinoreceptors in swine tracheal smooth muscle.
Topics: Animals; Atropine; Binding Sites; Carbachol; Epithelium; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Muscle, Smooth; Pilocarpine; Quinuclidines; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine; Swine; Temperature; Trachea; Tritium | 1986 |
Muscarinic cholinergic receptors in human foetal brain: characterization and ontogeny of [3H]quinuclidinyl benzilate binding sites in frontal cortex.
Topics: Adolescent; Adult; Animals; Binding, Competitive; Carbachol; Cerebral Cortex; Child, Preschool; Female; Fetus; Guanosine Triphosphate; Humans; Middle Aged; Pregnancy; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Quinuclidines; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Sodium Chloride | 1985 |
Muscarinic cholinergic binding in rat brain.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzilates; Binding Sites; Binding, Competitive; Brain; Brompheniramine; Carbachol; Chlorpheniramine; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methacholine Compounds; Microsomes; Mitochondria; Oxotremorine; Pilocarpine; Quaternary Ammonium Compounds; Quinuclidines; Rats; Receptors, Cholinergic; Scopolamine; Temperature; Time Factors; Tritium | 1974 |
[Relation between internal activity and magnitude of the maximal effect].
Topics: Acetylcholine; Animals; Carbachol; In Vitro Techniques; Miotics; Muscle, Smooth; Nicotinic Acids; Parasympathomimetics; Pilocarpine; Quinuclidines; Rats; Receptors, Drug; Stomach | 1971 |
[Timolol in combination with other glaucoma drugs (author's transl)].
Topics: Acetazolamide; Aged; Carbachol; Drug Therapy, Combination; Epinephrine; Female; Glaucoma; Humans; Male; Middle Aged; Propanolamines; Quinuclidines; Timolol | 1981 |
[The effect of antiglaucoma drugs on the depth of the anterior chamber (I)].
Topics: Adult; Anterior Chamber; Carbachol; Clonidine; Glaucoma; Humans; Middle Aged; Miotics; Moxisylyte; Pilocarpine; Propranolol; Quinuclidines; Timolol | 1982 |
Muscarinic receptor of rat pancreatic acini: [3H]QNB binding and amylase.
Topics: Amylases; Animals; Binding Sites; Carbachol; Male; Pancreas; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic; Tritium | 1981 |
125I-Labeled alpha-bungarotoxin and [3H]quinuclidinylbenzilate binding to rat brain membranes. Effects of physical, chemical and enzymatic treatments.
Topics: Animals; Brain; Bungarotoxins; Carbachol; Cations, Divalent; Disulfides; Egtazic Acid; Freezing; Iodine Radioisotopes; Kinetics; Quinuclidines; Quinuclidinyl Benzilate; Rats; Sulfhydryl Compounds; Sulfhydryl Reagents; Synaptic Membranes; Tritium | 1980 |
The biphasic response of muscarinic cholinergic receptors in cultured heart cells to agonists. Effects on receptor number and affinity in intact cells and homogenates.
Topics: Animals; Carbachol; Cell Membrane; Cells, Cultured; Chick Embryo; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Myocardium; N-Methylscopolamine; Quinuclidines; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives | 1982 |
Kindled seizures selectively reduce a subpopulation of [3H]quinuclidinyl benzilate binding sites in rat dentate gyrus.
Topics: Animals; Binding Sites; Carbachol; Hippocampus; Kindling, Neurologic; Male; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Seizures; Tritium | 1982 |
NGF promotes amyloid precursor protein secretion via muscarinic receptor activation.
Topics: Amyloid beta-Protein Precursor; Animals; Carbachol; Cell Differentiation; Cell Membrane; Dose-Response Relationship, Drug; Kinetics; Nerve Growth Factors; Parasympathomimetics; PC12 Cells; Quinuclidines; Rats; Receptors, Muscarinic; Recombinant Proteins; Tetradecanoylphorbol Acetate; Thiophenes; Time Factors; Transfection | 1995 |
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mulatta; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Quinuclidines | 1994 |
NGF-dependent neurotrophic-like effects of AF102B, an M1 muscarinic agonist, in PC12M1 cells.
Topics: Animals; Atropine; Carbachol; Cyclic AMP; Nerve Growth Factors; Parasympathomimetics; PC12 Cells; Quinuclidines; Rats; Thiophenes | 1995 |
Amyloid precursor protein secretion via muscarinic receptors: reduced desensitization using the M1-selective agonist AF102B.
Topics: Amyloid beta-Protein Precursor; Animals; Carbachol; Kinetics; Parasympatholytics; PC12 Cells; Quinuclidines; Receptors, Muscarinic; Recombinant Proteins; Thiophenes; Transfection | 1994 |
Muscarinic m3 receptors and dynamics of intracellular Ca2+ cerebellar granule neurons.
Topics: Animals; Calcium; Carbachol; Cells, Cultured; Cerebellum; Dantrolene; Diamines; Fura-2; Glutamates; Glutamic Acid; Microscopy, Fluorescence; Neurons; Parasympatholytics; Quinuclidines; Rats; Receptors, Glutamate; Receptors, Muscarinic; Terpenes; Thapsigargin; Xanthenes | 1993 |
Age does not affect contractile responses of the isolated rhesus monkey ciliary muscle to muscarinic agonists.
Topics: Aging; Animals; Atropine; Carbachol; Cells, Cultured; Ciliary Body; Culture Media; Ganglionic Stimulants; Macaca mulatta; Muscle Contraction; Muscles; Quinuclidines | 1993 |
Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands.
Topics: Adenylyl Cyclases; Animals; Arachidonic Acid; Calcium; Carbachol; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Hydrolysis; Phosphatidylinositols; Pilocarpine; Protein Binding; Quinuclidines; Receptors, Cholinergic; Signal Transduction; Thiophenes; Transfection | 1994 |
Activation of m1 muscarinic acetylcholine receptor regulates tau phosphorylation in transfected PC12 cells.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Drug Synergism; Muscarinic Agonists; Nerve Growth Factors; Neurons; PC12 Cells; Phosphorylation; Quinuclidines; Rats; Receptors, Muscarinic; tau Proteins; Thiophenes; Time Factors; Transfection | 1996 |
Aceclidine effects on outflow facility after ciliary muscle disinsertion.
Topics: Accommodation, Ocular; Animals; Aqueous Humor; Carbachol; Ciliary Body; Cytochalasin B; Dose-Response Relationship, Drug; Gonioscopy; Macaca mulatta; Male; Muscarinic Agonists; Muscle, Smooth; Pilocarpine; Quinuclidines; Trabecular Meshwork | 1996 |
In vitro characterisation of the muscarinic receptor partial agonist, sabcomeline, in rat cortical and heart membranes.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cell Membrane; Cells, Cultured; Cerebral Cortex; Drug Interactions; Heart; Imines; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth, Vascular; Myocardium; Oxotremorine; Quinuclidines; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Sprague-Dawley | 1999 |
Inhibitory effect of capsaicin on cholinergic transmission in ovine airways: evidence for non-cholinergic contractions.
Topics: Acetylcholine; Animals; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Lung; Muscle Contraction; Muscle, Smooth; Neural Inhibition; Neurokinin-1 Receptor Antagonists; Neuromuscular Junction; Peptides, Cyclic; Quinuclidines; Receptors, Drug; Receptors, Neurokinin-2; Serotonin; Sheep; Substance P; Synaptic Transmission; Trachea | 1999 |
Facilitation of cholinergic transmission by substance P methyl ester in the mouse hippocampal slice preparation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Carbachol; Cholinergic Agonists; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Hippocampus; Male; Membrane Potentials; Mice; Patch-Clamp Techniques; Piperidines; Pyramidal Cells; Quinuclidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Substance P; Tetrodotoxin; Valine | 2000 |
Direct effects of muscarinic agents on the outflow pathways in human eyes.
Topics: Aged; Anterior Eye Segment; Aqueous Humor; Atropine; Carbachol; Dose-Response Relationship, Drug; Humans; Muscarinic Agonists; Muscarinic Antagonists; Pilocarpine; Quinuclidines; Receptors, Muscarinic | 2000 |
Low-affinity M(2) receptor binding state mediates mouse atrial bradycardia: comparative effects of carbamylcholine and the M(1) receptor agonists sabcomeline and xanomeline.
Topics: Animals; Atropine; Bradycardia; Carbachol; Drug Interactions; Heart; Heart Rate; Imines; In Vitro Techniques; Mice; Muscarinic Agonists; Pyridines; Quinuclidines; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic; Thiadiazoles | 2001 |
Sensitization of enteric reflexes in the rat colon in vitro.
Topics: Animals; Area Under Curve; Carbachol; Cholinergic Agonists; Colon; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Granisetron; Hexamethonium; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Neurons, Afferent; Nicotinic Antagonists; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Tachykinin; Serotonin Antagonists; Time Factors | 2002 |
M(3) receptor antagonism by the novel antimuscarinic agent solifenacin in the urinary bladder and salivary gland.
Topics: Animals; Benzofurans; Bradycardia; Calcium; Carbachol; Cells, Cultured; Cytosol; Dose-Response Relationship, Drug; Female; Guinea Pigs; Humans; In Vitro Techniques; Isoquinolines; Kinetics; Male; Mandelic Acids; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pyrrolidines; Quinuclidines; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Salivary Glands; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder | 2002 |
Antinociception from lateral hypothalamic stimulation may be mediated by NK(1) receptors in the A7 catecholamine cell group in rat.
Topics: Animals; Antimutagenic Agents; Carbachol; Catecholamines; Cholinergic Agonists; Cobalt; Female; Hypothalamic Area, Lateral; Microinjections; Neural Pathways; Neurokinin-1 Receptor Antagonists; Nociceptors; Pain Threshold; Pons; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1 | 2002 |
Effect of SNI-2011 on amylase secretion from parotid tissue in rats and in neuronal nitric oxide synthase knockout mice.
Topics: Alkaloids; Amylases; Animals; Azepines; Benzoates; Benzylamines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Carbazoles; Chelating Agents; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Egtazic Acid; Enzyme Activation; Enzyme Inhibitors; Estrenes; Gallic Acid; Genotype; Guanylate Cyclase; Imidazoles; In Vitro Techniques; Indoles; Male; Mice; Mice, Knockout; Molsidomine; Muscarinic Agonists; Myosin-Light-Chain Kinase; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oxadiazoles; Parotid Gland; Penicillamine; Phosphodiesterase Inhibitors; Pilocarpine; Protein Kinase Inhibitors; Pyrroles; Pyrrolidinones; Quinoxalines; Quinuclidines; Rats; Rats, Wistar; Sulfonamides; Thiophenes; Type C Phospholipases | 2003 |
Comparison of in vitro selectivity profiles of solifenacin succinate (YM905) and current antimuscarinic drugs in bladder and salivary glands: a Ca2+ mobilization study in monkey cells.
Topics: Animals; Benzhydryl Compounds; Benzofurans; Calcium; Calcium Signaling; Carbachol; Cresols; Dose-Response Relationship, Drug; In Vitro Techniques; Inhibitory Concentration 50; Macaca fascicularis; Male; Mandelic Acids; Muscarinic Antagonists; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Solifenacin Succinate; Submandibular Gland; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder | 2004 |
Aceclidine and pilocarpine interact differently with muscarinic receptor in isolated rabbit iris muscle.
Topics: Animals; Carbachol; Iris; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Pilocarpine; Quinuclidines; Rabbits; Receptors, Muscarinic | 2006 |
Pharmacological characterization of a new antimuscarinic agent, solifenacin succinate, in comparison with other antimuscarinic agents.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzilates; Benzofurans; Binding, Competitive; Carbachol; CHO Cells; Cholinergic Agonists; Cresols; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mandelic Acids; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Phenylpropanolamine; Pyrrolidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Muscarinic; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Transfection; Urinary Bladder; Urinary Bladder, Overactive; Urination | 2007 |
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection | 2007 |
Comparative in vivo uroselectivity profiles of anticholinergics, tested in a novel anesthetized rabbit model.
Topics: Anesthesia; Animals; Benzhydryl Compounds; Benzofurans; Carbachol; Cholinergic Antagonists; Cresols; Injections, Intra-Arterial; Male; Mandelic Acids; Phenylpropanolamine; Pressure; Pyrrolidines; Quinuclidines; Rabbits; Salivary Glands; Solifenacin Succinate; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder | 2007 |
Effects of intravenously and orally administered solifenacin succinate (YM905) on carbachol-induced intravesical pressure elevation and salivary secretion in mice.
Topics: Administration, Oral; Anesthesia; Animals; Blood Pressure; Carbachol; Injections, Intravenous; Mice; Muscarinic Agonists; Muscarinic Antagonists; Quinuclidines; Salivation; Solifenacin Succinate; Tetrahydroisoquinolines | 2007 |
Pharmacological effects of solifenacin on human isolated urinary bladder.
Topics: Aged; Calcium Chloride; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; In Vitro Techniques; Male; Microdialysis; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Quinuclidines; Solifenacin Succinate; Tetrahydroisoquinolines; Urinary Bladder | 2008 |
Lateral hypothalamic-induced antinociception may be mediated by a substance P connection with the rostral ventromedial medulla.
Topics: Analgesics, Non-Narcotic; Analysis of Variance; Animals; Behavior, Animal; Carbachol; Cobalt; Female; Hypothalamic Area, Lateral; Medulla Oblongata; Neurons; Pain Measurement; Pain Threshold; Quinuclidines; Rats; Rats, Sprague-Dawley; Reaction Time; Serotonin Antagonists; Stilbamidines; Substance P; Time Factors | 2008 |
Inhibitory effect of quercetin on rat trachea contractility in vitro.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Benzamides; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phentolamine; Piperidines; Propranolol; Quercetin; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Trachea | 2009 |
An NK1 receptor antagonist microinjected into the periaqueductal gray blocks lateral hypothalamic-induced antinociception in rats.
Topics: Animals; Behavior, Animal; Carbachol; Cholinergic Agonists; Cobalt; Female; Foot; Hypothalamic Area, Lateral; Microinjections; Neurokinin-1 Receptor Antagonists; Pain; Pain Measurement; Pain Threshold; Periaqueductal Gray; Quinuclidines; Rats; Rats, Sprague-Dawley; Tail | 2009 |
Bronchodilator activity of (3R)-3-[[[(3-fluorophenyl)[(3,4,5-trifluorophenyl)methyl]amino] carbonyl]oxy]-1-[2-oxo-2-(2-thienyl)ethyl]-1-azoniabicyclo[2.2.2]octane bromide (CHF5407), a potent, long-acting, and selective muscarinic M3 receptor antagonist.
Topics: Acetylcholine; Aged; Anesthesia; Animals; Blood Pressure; Bronchi; Bronchial Spasm; Bronchoconstriction; Bronchoconstrictor Agents; Bronchodilator Agents; Carbachol; Carbamates; CHO Cells; Cricetinae; Cricetulus; Diamines; Guinea Pigs; Heart Atria; Heart Rate; Humans; Kinetics; Male; Middle Aged; Molecular Structure; Muscarinic Antagonists; Myocardial Contraction; Quinuclidines; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Scopolamine Derivatives; Tiotropium Bromide; Trachea; Transfection; Ventricular Function, Left | 2010 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium | 2011 |
Pharmacological characterization of GSK573719 (umeclidinium): a novel, long-acting, inhaled antagonist of the muscarinic cholinergic receptors for treatment of pulmonary diseases.
Topics: Administration, Inhalation; Animals; Calcium; Carbachol; CHO Cells; Cholinergic Antagonists; Cricetinae; Cricetulus; Guinea Pigs; Kinetics; Lung; Lung Diseases; Mice; Mice, Inbred BALB C; Muscarinic Agonists; Muscarinic Antagonists; Plethysmography; Quinuclidines; Receptor, Muscarinic M3; Receptors, Muscarinic; Scopolamine Derivatives; Tiotropium Bromide | 2013 |
Reactivity of human labial glands in response to cevimeline treatment.
Topics: Carbachol; Humans; Lip; Quinuclidines; Salivary Glands; Sjogren's Syndrome; Thiophenes | 2021 |