carbachol has been researched along with pirenzepine in 367 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 119 (32.43) | 18.7374 |
| 1990's | 182 (49.59) | 18.2507 |
| 2000's | 44 (11.99) | 29.6817 |
| 2010's | 20 (5.45) | 24.3611 |
| 2020's | 2 (0.54) | 2.80 |
| Authors | Studies |
|---|---|
| Kashima, K; Kataoka, K; Kato, M; Kuriyama, K; Ohkuma, S | 1 |
| Sastry, BV; Stephan, CC | 1 |
| Lau, WM; Szilagyi, M | 1 |
| Narayanan, N; Su, N | 1 |
| Abdallah, EA; Eldefrawi, AT; Eldefrawi, ME; Jett, DA | 1 |
| Hato, F; Kinoshita, Y; Tominaga, K; Tominaga, M; Yamada, M | 1 |
| Chen, HY; Lee, EH; Lin, YP | 1 |
| Bungardt, E; Feifel, R; Lambrecht, G; Moser, U; Mutschler, E; Surprenant, A; Tacke, R; Vockert, E | 1 |
| Brading, AF; Parekh, AB | 1 |
| Martin, JR | 1 |
| Lebrun, F; Marchetti, J; Morel, F; Vassent, G | 1 |
| Flynn, DD; Mash, DC; Vaishnav, AA | 1 |
| Li, M; Morley, P; Schwartz, JL; Tsang, BK; Whitfield, JF | 1 |
| Boland, CR; Kraus, ER; Scheiman, JM; Shimakura, S; Yoshimura, K | 1 |
| Dunant, Y; Sierro, CD; Vitus, J | 1 |
| Funakoshi, A; Jimi, A; Kono, A; Tateishi, K; Tsuru, M; Wakasugi, H | 1 |
| Buyse, MA; Fraeyman, NH; Lefebvre, RA | 1 |
| Challiss, RA; Nahorski, SR; Whitham, EM | 1 |
| FitzGibbon, F; Osborne, NN; Schwartz, G | 1 |
| Fowler, CJ; Tiger, G | 1 |
| Akerman, KE; Heikkilä, J; Jansson, C | 1 |
| Akerman, KE; Jansson, CC; Kukkonen, J | 1 |
| Bhattacharya, SK; Das Gupta, G; Sen, AP; Seth, K; Seth, PK | 1 |
| Gies, JP; Haddad, EB; Landry, Y | 1 |
| Richards, MH | 2 |
| Daniel, EE; Janssen, LJ | 1 |
| Choo, LK; Mitchelson, F | 1 |
| Atkins, PT; Kitai, ST; Nishi, K; Surmeier, DJ | 1 |
| Matsumoto, K; Pappano, AJ | 1 |
| Choo, LK; Darroch, SA; Gardner, A; Mitchelson, F; Vong, YM | 1 |
| Cost, M; Majewski, H | 1 |
| Donoff, B; Lad, R; Rangachari, PK | 1 |
| Alonso, MJ; Arribas, S; Balfagón, G; Marín, J; Salaices, M | 1 |
| Barker, JL; Fiszman, ML; Jones, SV | 1 |
| Goldman-Rakic, PS; Vannucchi, MG | 1 |
| Bohnett, M; Ellerbrock, BR; Messer, WS | 1 |
| Akaike, N; Harata, N; Tateishi, N | 1 |
| Chiba, S; Furukawa, Y; Nakane, T | 1 |
| Costa, G; Massi, M; Melchiorre, C; Perfumi, M; Polidori, C; Sajia, A | 1 |
| Brudzynski, SM; Girvin, JP; McLachlan, RS | 1 |
| Hersey, SJ; Kajimura, M; Sachs, G; Scott, DR; Wilkes, JM | 1 |
| Benedito, S; García-Sacristán, A; Hernández, M; Prieto, D; Rivera, L | 1 |
| Bredt, DS; Hwang, PM; Snyder, SH | 1 |
| Konda, Y; Matozaki, T; Matsuda, K; Nagao, M; Nakano, O; Nishisaki, H; Sakamoto, C; Wada, K | 1 |
| Yang, CM | 1 |
| Flynn, DD; Mash, DC; Weinstein, DA | 1 |
| Felix, W; Schneider, E | 1 |
| Alger, BE; Pitler, TA | 1 |
| Gomez, A; Laukonnen, S; Marquez, E; Martos, F; Pavia, J; Rius, F; Sanchez de la Cuesta, F | 1 |
| Boselli, C; Kenakin, TP | 1 |
| Ghodsi-Hovsepian, S; Hoss, W; Messer, WS | 1 |
| Harbon, S; Leiber, D; Marc, S | 1 |
| Fleming, N; Laniyonu, A; Sliwinski-Lis, E | 1 |
| Bizzarri, C; Corda, D; D'Orazio, MC; Di Girolamo, M | 1 |
| el-Fakahany, EE; Forray, C | 1 |
| Bloom, JW; Lai, J; Roeske, WR; Yamamura, HI | 1 |
| Björklund, PE; Fowler, CJ; Tiger, G | 1 |
| Buck, MA; Fraser, CM | 1 |
| Hartmann, T; Kahan, C; Pouyssegur, J; Seuwen, K | 1 |
| Lebrun, F; Marchetti, J; Morel, F; Taniguchi, S | 1 |
| Hanack, C; Herawi, M; Kopp, R; Lambrecht, G; Moser, U; Mutschler, E; Pfeiffer, A; Tacke, R | 1 |
| de Pont, JJ; Rodrigues de Miranda, JF; van Ginneken, CA; van Zwam, AJ; Willems, PH | 1 |
| Fischofer-Hahn, C; McLeskey, SW; Takahashi, K; Wojcik, WJ | 1 |
| Sheridan, RD; Sutor, B | 1 |
| Protas, LL | 1 |
| Costi, A; Marchi, M; Raiteri, M; Volpe, G | 1 |
| Akahane, K; Chiba, S; Furukawa, Y; Karasawa, Y | 1 |
| Pietrzak, ER; Shanley, BC; Wilce, PA | 1 |
| Haga, T; Honda, N; Ichiyama, A; Kajimura, M; Kaneko, E | 1 |
| Bagetta, G; Constanti, A | 1 |
| Lambrecht, G; Massi, M; Melchiorre, C; Mutschler, E; Polidori, C; Tacke, R | 1 |
| Dwyer, TM; Farley, JM; Ho, IK; Mohan, PM; Yang, CM | 1 |
| Araujo, DM; Collier, B; Lapchak, PA; Meaney, MJ; Quirion, R | 1 |
| Baba, S; Fujii, M; Nakamura, T; Oka, T; Okabayashi, Y; Otsuki, M | 3 |
| Bartus, RT; Fisher, SK | 1 |
| Ackerman, MS; Korc, M; Roeske, WR | 1 |
| McKinney, M; Rubanyi, GM; Vanhoutte, PM | 1 |
| Arhem, P; Hedlund, B; Lorentz, M | 1 |
| Bradshaw, CM; Sheridan, RD; Szabadi, E | 1 |
| Bowker, P; Daniel, EE; Jury, J | 1 |
| Clementi, F; Gotti, C; Madeddu, L; Pandiella, A; Sher, E | 1 |
| Hawthorne, JN; Simmonds, SH; Yagisawa, H | 1 |
| Arrang, JM; Gulat-Marnay, C; Lafitte, A; Schwartz, JC | 1 |
| Baba, S; Fujii, M; Fujisawa, T; Nakamura, T; Okabayashi, Y; Otsuki, M; Tani, S | 1 |
| Goritski, W; Mega, A; Nattie, EE; Wood, J | 1 |
| Misgeld, U; Müller, W | 2 |
| Gerber, U; Greene, RW; Haas, HL; McCarley, RW | 1 |
| Anderson, D; McKinney, M; Vella-Rountree, L | 1 |
| Laitinen, JT; Saavedra, JM; Torda, T | 2 |
| Kopp, R; Lambrecht, G; Moser, U; Mutschler, E; Pfeiffer, A; Tacke, R | 1 |
| Misgeld, U; Müller, W; Polder, HR | 1 |
| Hung, WC; Wei, JW | 1 |
| Marchi, M; Raiteri, M | 2 |
| Gil, DW; Wolfe, BB | 1 |
| Brown, JH; Goldstein, D; Masters, SB | 1 |
| Choo, LK; Mitchelson, F; Vong, YM | 1 |
| Flynn, DD; Palermo, N; Suarez, A | 1 |
| Cotman, CW; Kahle, JS | 1 |
| Court, JA; Keith, AB; Perry, EK; Smith, CJ | 1 |
| Ackerman, MS; Heck, RJ; Korc, M; Roeske, WR | 1 |
| Ghataorre, AS; Lambert, DG; Nahorski, SR | 1 |
| Boselli, C; Kenakin, T | 1 |
| Delmendo, R; Michel, AD; Stefanich, E; Whiting, RL | 1 |
| Araujo, DM; Collier, B; Lapchak, PA; Quirion, R | 2 |
| Borasio, PG; Capuzzo, A; Fabbri, E | 1 |
| Cornett, CM; Eglen, RM; Kunysz, EA; Michel, AD; Whiting, RL | 1 |
| Herz, A; Paumgartner, G; Pfeiffer, A; Rochlitz, H | 1 |
| Hadjiconstantinou, M; Moroi-Fetters, SE; Neff, NH | 1 |
| Alger, BE; McCarren, M; Pitler, TA | 1 |
| Ek, B; Nahorski, S | 1 |
| Amrhein, CL; Cioffi, CL; el-Fakahany, EE; McKinney, M; Richelson, E; Stenstrom, S; Surichamorn, W | 1 |
| Gatti, G; Madeddu, L; Meldolesi, J; Pandiella, A; Pozzan, T | 1 |
| Soll, AH; Sue, R; Todisco, A; Toomey, ML; Yamada, T | 1 |
| Critchett, DJ; Joseph, JA; Lippa, AS | 1 |
| Giachetti, A; Micheletti, R; Montagna, E | 1 |
| Kunysz, EL; Michel, AD; Whiting, RL | 1 |
| Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H; Pruitt, RE; Uemura, N | 1 |
| Baghdoyan, HA; Lydic, R; Zwillich, CW | 1 |
| McKinney, M; Richelson, E; Stenstrom, S | 1 |
| Morrow, C; Murphy, S; Pearce, B | 1 |
| Akiyama, K; Reisine, TD; Roeske, WR; Smith, TL; Vickroy, TW; Watson, M; Yamamura, HI | 1 |
| Costa, E; Eva, C | 1 |
| Chuang, DM | 1 |
| Barnes, PJ; Cuss, FM; Grandordy, BM; Palmer, JB; Sampson, AS | 1 |
| Hoffman, PL; Luthin, GR; Moses, F; Tabakoff, B | 1 |
| Cioffi, CL; el-Fakahany, EE | 1 |
| McKinney, M; Richelson, E | 1 |
| Lee, L; Smith, TL; Yamamura, HI | 1 |
| Chuang, DM; Xu, J | 1 |
| Mei, L; Roeske, WR; Wang, JX; Yamamura, HI | 1 |
| Allescher, HD; Berezin, I; Daniel, EE; Jury, J | 1 |
| Kigoshi, S; Muramatsu, I; Yamanaka, K | 2 |
| Camus, J; Christophe, J; De Neef, P; Fourmy, D; Pradayrol, L; Robberecht, P; Scemama, JL; Tastenoy, M; Vaysse, N; Waelbroeck, M | 1 |
| Benson, DM; Blitzer, RD; Landau, EM | 1 |
| Abdel-Latif, AA; Honkanen, RE | 1 |
| Carmeliet, P; Denef, C | 1 |
| Herawi, M; Lambrecht, G; Moser, U; Mutschler, E; Pfeiffer, A | 1 |
| McCarthy, BG; Peroutka, SJ | 1 |
| Dwyer, TM; Farley, JM; Yang, CM | 1 |
| Audigier, SM; Greengard, P; Wang, JK | 1 |
| Davidesko, D; Doods, HN; Rinner, I; van Charldorp, KJ; van Zwieten, PA | 1 |
| Berstein, G; Haga, K; Haga, T; Ichiyama, A | 1 |
| Araujo, DM; Gauthier, S; Lapchak, PA; Quirion, R; Robitaille, Y | 1 |
| Chung, FZ; Lai, J; Mei, L; Roeske, WR; Venter, JC; Yamamura, HI | 1 |
| Adem, A; Nordberg, A; Sabbagh, M | 1 |
| Bartfai, T; Goobar, L | 1 |
| Constanti, A; Williams, SH | 1 |
| Ebinger, G; Vanderheyden, P; Vauquelin, G | 2 |
| Newberry, NR; Priestley, T | 1 |
| Abdel-Latif, AA; Akhtar, RA; Honkanen, RE; Howe, PH | 1 |
| Ringdahl, B | 1 |
| Hoss, W; Messer, WS; Price, M; Thomas, GJ | 1 |
| Bali, JP; Baudiere, B; Giraldo, E; Ladinsky, H; Monferini, E | 1 |
| Collins, AC; Marks, MJ; Romm, E | 1 |
| Smith, TL; Yamamura, HI | 2 |
| Cortés, R; Cymerman, U; Palacios, JM; Skangiel-Kramska, J | 1 |
| Adam, LP; Pappano, AJ; Sorota, S | 1 |
| Roeske, WR; Watson, M; Yamamura, HI | 1 |
| Baba, S; Matozaki, T; Nagao, M; Sakamoto, C | 1 |
| Herz, A; Paumgartner, G; Pfeiffer, A | 1 |
| Horváth, E; Spencer, DG; Traber, J; Van Rooijen, LA | 1 |
| De Backer, JP; Ebinger, G; Vanderheyden, P; Vauquelin, G | 1 |
| Agranoff, BW; Ernst, SA; Lowy, RJ; Roland, RM; Snider, RM | 1 |
| Cubeddu, LX; James, MK | 1 |
| Bloom, JW; Halonen, M; Lawrence, LJ; Rould, E; Seaver, NA; Yamamura, HI | 1 |
| Barker, JL; Hedlund, B | 1 |
| Eglen, RM; Whiting, RL | 1 |
| Gremo, F; Marchisio, AM; Mulas, ML; Palomba, M | 1 |
| Aronstam, RS; Kirby, ML; Smith, MD | 1 |
| Gremo, F; Marchisio, AM; Vernadakis, A | 1 |
| Luthin, GR; Wolfe, BB | 1 |
| Kendall, DA; Lazareno, S; Nahorski, SR | 1 |
| Newberry, NR; Priestley, T; Woodruff, GN | 1 |
| Rosenfeld, GC | 1 |
| Cortés, R; Palacios, JM; Pazos, A | 1 |
| Miederer, SE; Ruoff, HJ; Schepp, W | 1 |
| Fleissig, W; Leitold, M; Merk, A | 1 |
| Baissat, J; Chassaing, C; Duchêne-Marullaz, P; Dureng, G | 1 |
| Christophe, J; Dehaye, JP; Hermans, L; Poloczek, P; Winand, J | 1 |
| Albinus, M; Winne, D | 1 |
| Bárány, E; Berrie, CP; Birdsall, NJ; Burgen, AS; Hulme, EC | 1 |
| Hammer, R | 1 |
| Hackmiller, RC; Jumblatt, JE | 1 |
| Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Bacman, S; Borda, E; Camusso, JJ; Rodriguez, M; Sterin-Borda, L | 1 |
| Celesia, GG; Ladner, CJ; Lee, JM; Magnuson, DJ | 1 |
| Birmingham, AT; Harriss, DR; Hill, SJ; Marsh, KA | 1 |
| Marks, GA; Roffwarg, HP | 1 |
| Ogren, SO; Pramanik, A | 1 |
| Hotta, K; Ishihara, K; Kojima, Y; Komuro, Y; Saigenji, K | 1 |
| Classen, M; Schaffer, K; Schepp, W; Schusdziarra, V; Wegner, U; Weigert, N | 1 |
| Gabelt, BT; Kaufman, PL; Poyer, JF | 1 |
| Besson, MJ; Gioanni, H; Kayadjanian, N; Ménetrey, A | 1 |
| Fukui, H; Inagaki, N; Kondou, H | 1 |
| Dorsey, WC; Ford, BD; Townsel, JG | 1 |
| Takaki, T; Tanaka, M; Yamada, S; Yokoo, H | 1 |
| Ferrari-DiLeo, G; Flynn, DD; Mash, DC | 1 |
| Haass, M; Haunstetter, A; Krüger, C; Kübler, W; Yi, X | 1 |
| Homayoun, P; Kalaria, RN; Whitehouse, PJ | 1 |
| Błaszczyk, M; Eckersdorf, B; Gołebiewski, H; Grabowski, R; Konopacki, J | 1 |
| Calvet, GA; Ventura, AL | 1 |
| DelValle, J; Park, J; Yamada, T; Yokotani, K | 1 |
| Säfsten, B | 1 |
| Akaike, N; Furukawa, K; Nabekura, J | 1 |
| Anthony, TL; Kreulen, DL | 1 |
| Almazan, G; Cohen, RI | 1 |
| Larocca, JN; Lyman, WD; Rashbaum, WK; Rodriguez-Gabin, AG; Weidenheim, KM | 1 |
| Kaneko, S; Maeda, T; Satoh, M | 2 |
| Choi, A; Mitchelson, F | 1 |
| Cynader, MS; Gu, Q; Haugland, RP; Mao, F; Wang, Y | 1 |
| Dauphin, F; Hamel, E; Linville, DG | 1 |
| Bobbin, RP; Erostegui, C; Norris, CH | 1 |
| Costa, LG; Tan, XX | 1 |
| Allescher, HD; Classen, M; Kurjak, M; Schusdziarra, V | 1 |
| Iwamoto, ET; Marion, L | 1 |
| el-Fakahany, EE; Hu, J | 1 |
| Brasitus, TA; Khare, S; Tien, XY; Wilson, DM | 1 |
| De Klippel, N; Ebinger, G; Michotte, Y; Sarre, S | 1 |
| Alloatti, G; Eva, C; Gallo, MP; Levi, RC; Oberto, A | 1 |
| Angeli, P; Bianchi, S; Imeri, L; Mancia, M | 1 |
| Harty, RF; Ren, J | 1 |
| Abdel-Latif, AA; Akhtar, RA; Tachado, SD; Virdee, K | 1 |
| Greten, H; Mirau, S; Raedler, A; Sievers, J; von Schrenck, T | 1 |
| Moran, A; Turner, RJ | 1 |
| Chuang, DM; Fukamauchi, F; Hough, C; Saunders, PA | 1 |
| Ferrari-DiLeo, G; Flynn, DD | 1 |
| Czerwiec, E; de Backer, JP; de Potter, W; Vauquelin, G | 1 |
| Olianas, MC; Onali, P | 1 |
| Antonsson, BM; Ek, B | 1 |
| Aceves, J; Arias-Montaño, JA; Young, JM | 1 |
| Eglen, RM; Sharif, NA; To, ZP | 1 |
| Consolo, S; Garcia Ruiz, AJ; La Porta, C; Ladinsky, H; Zambelli, M | 1 |
| Fain, JN; Sallés, J; Wallace, MA | 1 |
| Tonnaer, JA; van Huizen, F | 1 |
| Bemis, KG; Bymaster, FP; Health, I; Mitch, CH; Sawyer, BD; Shannon, HE; Ward, JS | 1 |
| Gilbert, KA; Lydic, R | 1 |
| Shiraishi, K; Takayanagi, I | 1 |
| Bargas, J; Flores-Hernández, J; Galarraga, E; Pineda, JC | 1 |
| Fuxe, K; Odagaki, Y | 1 |
| Bacáková, L; el-Fakahany, EE; Jakubík, J; Tucek, S | 1 |
| Garland, CJ; Hillier, K; Kerr, PM; Wallis, RM | 1 |
| Borda, E; Echagüe, AV; Genaro, A; Leiros, CP; Sterin-Borda, L | 1 |
| Jones, SB; King, LB | 1 |
| Sjögren, C; Tobin, G | 1 |
| Goto, Y; Maeyama, K | 1 |
| Avellino, C; Battaini, F; Fortuna, S; Lorenzini, P; Malvezzi Campeggi, L; Pascale, A; Pintor, A; Salvati, S | 1 |
| Bartolini, A; Galeotti, N; Ghelardini, C; Gualtieri, F; Teodori, E | 1 |
| De Neef, P; Domenach, V; Vandermeers, A; Vandermeers-Piret, MC; Waelbroeck, M | 1 |
| de la Vega, MT; Montano, JA; Nunez, A | 1 |
| Brann, MR; Bräuner-Osborne, H; Ebert, B; Falch, E; Krogsgaard-Larsen, P | 1 |
| Tobin, G | 1 |
| Travagli, RA | 1 |
| Latifpour, J; Mutoh, S; Saito, M; Weiss, RM | 1 |
| Spindler, KD; Spindler-Barth, M; Wegener, S | 1 |
| Arana, R; Bacman, S; Borda, E; Camusso, JJ; Hubscher, O; Sterin-Borda, L | 1 |
| Akaike, A; Kaneko, S; Maeda, T; Satoh, M; Shimoshige, Y | 1 |
| Aslan, N; Gören, Z; Oktay, S; Onat, F; Ozkutlu, U | 1 |
| Levin, RJ; Przyborski, SA | 1 |
| Matthews, MR; Zaidi, ZF | 1 |
| Semba, K; White, TD | 1 |
| Aslan, N; Gören, Z; Oktay, S; Onat, F | 1 |
| Cuadra, AE; El-Fakahany, EE | 1 |
| Arias-Montaño, JA; de la Vega, MT; Nuñez, A | 1 |
| Kauer, JA; Williams, JH | 1 |
| Koistinaho, J; Kurkinen, KM; Laitinen, JT | 1 |
| Alfonzo, MJ; de Alfonzo, RG; de Becemberg, IL; de Herrera, VN; de Villaroel, SS; Misle, AJ | 1 |
| Baba, H; Goldstein, PA; Kohno, T; Okamoto, M; Shimoji, K; Yoshimura, M | 1 |
| Cobuzzi, A; Lai, FM; Spinelli, W | 1 |
| Komori, S; Nakayama, T; Ohashi, H; Unno, T | 1 |
| Gorelick, FS; Modlin, IM; Nathanson, MH; Rhee, S; Scheele, GA; Schmid, SW; Stoch, A; Tang, LH | 1 |
| Dement, WC; Mignot, E; Nishino, S; Reid, MS; Siegel, JM; Tafti, M | 1 |
| Beck, M; Jánossy, A; Jurányi, Z; Orsó, E; Szalay, KS; Vinson, GP; Vizi, ES | 1 |
| Kawana, S; Miyamoto, A; Namiki, A; Ohshika, H; Yamamoto, S | 1 |
| Arai, H; Inoie, M; Marubuchi, S | 1 |
| Bargas, J; Galarraga, E; Hernández-Echeagaray, E | 1 |
| Bajo, VM; Criado, JM; de la Fuente Juan, A; Heredia, M; Riolobos, AS; Yajeya, J | 1 |
| Adrien, J; Ahnaou, A; Bourgin, P; Hamon, M; Laporte, AM | 1 |
| Brown, DA; Caulfield, MP; Fernandez-Fernandez, JM; Halley, P; Wanaverbecq, N | 1 |
| Haapalinna, A; Larson, J; Niittykoski, M; Ruotsalainen, S; Sirviö, J | 1 |
| Hu, HZ; Li, ZW; Shao, M | 1 |
| Christopoulos, A; El-Fakahany, EE; Parsons, AM | 1 |
| Bernardi, G; Bonci, A; Grillner, P; Mercuri, NB; Svensson, TH | 1 |
| Ladner, CJ; Lee, JM | 1 |
| Chitravanshi, VC; Sapru, HN | 1 |
| Acs, Z; Makara, GB; Némethy, Z | 1 |
| Müller, W; Richter, M; Schilling, T | 1 |
| Christopoulos, A; El-Fakahany, EE; Lew, MJ; Parsons, AM | 1 |
| Arellano, RO; Garay, E; Miledi, R | 1 |
| Gossell-Williams, MD; Simon, OR; West, ME; Wynter-Adams, DM | 1 |
| Conn, PJ; Hamilton, SE; Nathanson, NM; Potter, LT; Rouse, ST | 1 |
| Cohen, ML; Gomeza, J; Stengel, PW; Wess, J | 1 |
| Malomough, A; Naumenko, N; Nikolsky, E; Urazaev, A; Vyskocil, F | 1 |
| Levendusky, M; Longhurst, PA | 1 |
| Daniels, DV; Eglen, RM; Ford, AP; Hegde, SS; Meloy, TD | 1 |
| Christopoulos, A; Lanzafame, A; Mitchelson, F | 1 |
| Beltz, TG; Bhatty, RA; Johnson, AK; Johnson, RF; Sharma, RV; Xu, Z | 1 |
| Franco, W; Leite, RS | 1 |
| Alzheimer, C; Seeger, T | 1 |
| Herzog, M; Liu, J; Scherer, EQ; Scofield, MA; Shimozono, M; Wangemann, P | 1 |
| Delbro, DS; Giglio, D; Tobin, G | 1 |
| Pérez Leirós, C; Rosignoli, F | 1 |
| Cohen, ML; Stengel, PW | 1 |
| Shapovalova, KB | 1 |
| de Araujo, EG; dos Santos, AA; Medina, SV; Sholl-Franco, A | 1 |
| Fukumori, R; Goshima, Y; Hagiwara, Y; Kanaya, T; Kubo, T; Okatani, H | 1 |
| Gomeza, J; Klebroff, W; Trendelenburg, AU; Wess, J; Zhou, H | 1 |
| Brandish, PE; Hill, LA; Scolnick, EM; Zheng, W | 1 |
| Chen, HZ; Jin, ZJ; Qiu, Y; Wu, XJ | 1 |
| Borda, E; Busch, L | 1 |
| Romański, KW | 1 |
| Crittenden, EL; García, DM; González, A | 1 |
| Bukharaeva, EA; Magazanik, LG; Nikolsky, EE; Samigullin, D; Vyskocil, F | 1 |
| Freund, TF; Hájos, N; Pálhalmi, J; Paulsen, O | 1 |
| Frishman, LJ; Glasser, A; Ostrin, LA | 1 |
| deToledo-Morrell, L; Mash, DC; Rossi, MA | 1 |
| Aihara, T; Matsui, M; Nakamura, Y; Okabe, S; Taketo, MM | 1 |
| Shapvalova, KB | 1 |
| Borda, E; Orman, B; Reina, S; Sterin-Borda, L | 1 |
| Avellar, MC; Maróstica, E; Porto, CS; Siu, ER; Yasuhara, F | 1 |
| Kwon, KI; Lee, BH; Lee, CO; Woo, SH | 1 |
| de Groat, WC; Ng, YK; Wu, HY | 1 |
| Arias-Montaño, JA; Sánchez-Lemus, E | 1 |
| Miyazu, M; Ohinata, H; Sugawara, R; Takai, A; Takai, Y; Yoshida, A | 1 |
| Borda, ES; Casanova, M; Furlán, C; Sterin-Borda, L | 1 |
| Cao, J; Hashiba, K; Kitazawa, T; Komori, S; Taneike, T; Unno, T; Wess, J; Yamada, M | 1 |
| Chapple, CR; Chess-Williams, R; Stevens, LA | 1 |
| Hirose, K; Kaeriyama, S; Muramatsu, A; Nouchi, H; Sato, M; Shigenobu, K; Shimizu, N; Tanaka, H | 1 |
| Carr, DB; Surmeier, DJ | 1 |
| Ehlert, FJ; Figueroa, KW; Griffin, MT; Liller, S | 1 |
| Andersson, M; Aronsson, P; Delbro, DS; Giglio, D; Haraldsson, B; Tobin, G | 1 |
| Pitchford, S | 1 |
| Luo, L; Luo, Y; Ruan, DY; Tang, M; Wang, H; Wang, M; Zhu, D | 1 |
| Gelperin, A; Ghatpande, AS | 1 |
| Kaba, H; Takahashi, Y | 1 |
| Anisuzzaman, AS; Muramatsu, I; Nishimune, A; Uwada, J; Yoshiki, H | 1 |
| Gajdus, M; Glaza, I; Olkowska, J; Szadujkis-Szadurski, L; Szadujkis-Szadurski, R | 1 |
| Gajdus, M; Glaza, I; Olkowska, J; Szadujkis-Szadurska, K; Szadujkis-Szadurski, L; Szadujkis-Szadurski, R | 1 |
| Kitazawa, T; Komori, S; Kondo, T; Nakajima, M; Teraoka, H; Unno, T; Yamada, M | 1 |
| Jragh, DM; Khan, I; Oriowo, MA | 1 |
| Chess-Williams, R; Moro, C; Uchiyama, J | 1 |
| Benninghoff, J; Brantl, V; Moessner, R; Möller, HJ; Rauh, W; Rujescu, D; Schloesser, RJ | 1 |
| Kajioka, S; Naito, S; Seki, N; Shahab, N | 1 |
| Csernoch, L; Fu, Y; Kőszeghy, Á; Paxinos, G; Rusznák, Z; Szücs, G; Vincze, J | 1 |
| Andersson, M; Aronsson, P; Doufish, D; Lampert, A; Tobin, G | 1 |
| Dehnicke, C; Deisz, RA; Gigout, S; Horn, P; Lehmann, TN; Wierschke, S | 1 |
| Barnes, PJ; Brown, SM; Donnelly, LE; Koarai, A; Nicholson, AG; Sturton, RG | 1 |
| Chapman, CA; Glasgow, SD | 1 |
| Arrighi, N; Bodei, S; Cosciani Cunico, S; Michel, MC; Sigala, S; Simeone, C; Spano, P; Zani, D | 1 |
| Chu, V; Conde, JP; Martins, SA; Monteiro, GA; Moulas, G; Prazeres, DM; Trabuco, JR | 1 |
| Zefirov, AL; Zefirov, TL; Ziyatdinova, NI | 1 |
| Anderson, RW; Strowbridge, BW | 1 |
| Avoli, M; Cataldi, M; Chen, LY; Hamidi, S; Lévesque, M | 1 |
| Buyukafsar, K; Cevik, OS; Koyuncu, DD; Sahin, L | 1 |
| Hassanpour, S; Lankarani Mohajer, L; Zendehdel, M | 1 |
| Chu, V; Conde, JP; Martins, SAM; Prazeres, DMF | 1 |
2 review(s) available for carbachol and pirenzepine
| Article | Year |
|---|---|
Pharmacology and second messenger interactions of cloned muscarinic receptors.
Topics: Animals; Atropine; Carbachol; Cell Line; Humans; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic; Recombinant Proteins; Second Messenger Systems; Transfection | 1991 |
Cardioselective muscarinic antagonists.
Topics: Animals; Carbachol; Cardiotonic Agents; Carrier Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Dose-Response Relationship, Drug; Heart; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Pirenzepine; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
365 other study(ies) available for carbachol and pirenzepine
| Article | Year |
|---|---|
Characterization of muscarinic receptor subtypes on rat pancreatic acini: pharmacological identification by secretory responses and binding studies.
Topics: Amylases; Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Male; Pancreas; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sincalide | 1992 |
Characterization of the subtype of muscarinic receptor coupled to the stimulation of phosphoinositide hydrolysis in 132-1N1 human astrocytoma cells.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Astrocytoma; Atropine; Carbachol; Diamines; Humans; Hydrolysis; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine; Tumor Cells, Cultured | 1992 |
A pharmacological profile of glycopyrrolate: interactions at the muscarinic acetylcholine receptor.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Binding, Competitive; Carbachol; Diamines; Female; Gallamine Triethiodide; Glycopyrrolate; Guinea Pigs; In Vitro Techniques; Ligands; Muscarinic Antagonists; Myocardial Contraction; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate | 1992 |
Enhanced chronotropic and inotropic responses of rat myocardium to cholinergic stimulus with aging.
Topics: Acetylcholine; Acetylcholinesterase; Aging; Animals; Carbachol; Heart; Heart Rate; In Vitro Techniques; Male; Muscarinic Antagonists; Muscle Proteins; Myocardial Contraction; Myocardium; Parasympathetic Nervous System; Parasympatholytics; Parasympathomimetics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred F344 | 1992 |
Differential effects of paraoxon on the M3 muscarinic receptor and its effector system in rat submaxillary gland cells.
Topics: Animals; Atropine; Binding Sites; Carbachol; Cyclic AMP; Hydrolysis; Male; Paraoxon; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Regression Analysis; Submandibular Gland | 1992 |
Enhancement of DNA synthesis in rat thymocytes by stimulating their muscarinic acetylcholine receptors.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cells, Cultured; DNA; Hexamethonium; Hexamethonium Compounds; Isoflurophate; Kinetics; Male; Nicotine; Oxotremorine; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Succinylcholine; T-Lymphocytes; Thymidine; Tritium; Tubocurarine | 1992 |
Cholinergic and GABAergic mediations of the effects of apomorphine on serotonin neurons.
Topics: Acetylcholine; Analysis of Variance; Animals; Apomorphine; Atropine; Bicuculline; Carbachol; gamma-Aminobutyric Acid; Hydroxyindoleacetic Acid; Male; Mecamylamine; Neurons; Pirenzepine; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Tryptophan | 1992 |
Characterization of muscarinic receptors mediating vasodilation in guinea-pig ileum submucosal arterioles by the use of computer-assisted videomicroscopy.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arterioles; Benzodiazepinones; Carbachol; Guinea Pigs; Ileum; Methacholine Chloride; Muscarine; Muscarinic Antagonists; Oxotremorine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Prostaglandin Endoperoxides, Synthetic; Receptors, Muscarinic; Vasodilation | 1992 |
The M3 muscarinic receptor links to three different transduction mechanisms with different efficacies in circular muscle of guinea-pig stomach.
Topics: Animals; Carbachol; Female; Gallamine Triethiodide; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Pirenzepine; Receptors, Muscarinic; Signal Transduction | 1992 |
Pressor response to posterior hypothalamic administration of carbachol is mediated by muscarinic M3 receptor.
Topics: Animals; Atropine Derivatives; Blood Pressure; Carbachol; Diamines; Dose-Response Relationship, Drug; Hypothalamus, Posterior; Kinetics; Male; Microinjections; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1992 |
Cholinergic effects on intracellular free calcium concentration in renal corpuscle: role of parietal sheet.
Topics: Acetylcholine; Animals; Atropine; Calcium; Carbachol; Dose-Response Relationship, Drug; Histological Techniques; Intracellular Membranes; Kidney Glomerulus; Male; Osmolar Concentration; Parasympathomimetics; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Cholinergic | 1992 |
Interactions of cocaine with primary and secondary recognition sites on muscarinic receptors.
Topics: Adult; Allosteric Site; Binding Sites; Brain Stem; Carbachol; Cocaine; Ethylmaleimide; Guanine Nucleotides; Humans; In Vitro Techniques; Kinetics; Male; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1992 |
Muscarinic cholinergic stimulation elevates intracellular pH in chicken granulosa cells by a Ca(2+)-dependent, Na(+)-independent mechanism.
Topics: Animals; Atropine; Calcium; Carbachol; Chickens; Cytosol; Female; Fluoresceins; Granulosa Cells; Hydrogen-Ion Concentration; Pirenzepine; Receptors, Muscarinic; Sodium | 1992 |
Role of prostaglandin E2 in cholinergic-mediated glycoprotein synthesis in canine antrum.
Topics: Animals; Carbachol; Dinoprostone; Dogs; Gastric Mucosa; Indomethacin; Mucins; Parasympathetic Nervous System; Pirenzepine; Pyloric Antrum; Second Messenger Systems | 1992 |
Effects of muscarinic agonists and depolarizing agents on inositol monophosphate accumulation in the rabbit vagus nerve.
Topics: Acetylcholine; Animals; Arecoline; Cadmium; Calcimycin; Calcium; Carbachol; Dose-Response Relationship, Drug; Hydrolysis; Inositol Phosphates; Lithium; Ouabain; Oxotremorine; Parasympathomimetics; Pirenzepine; Potassium; Rabbits; Receptors, Muscarinic; Time Factors; Vagus Nerve | 1992 |
Acetylcholine regulates pancreastatin secretion from the human pancreastatin-producing cell line (QGP-1N).
Topics: Acetylcholine; Adenoma, Islet Cell; Atropine; Calcimycin; Calcium; Carbachol; Chromogranin A; Gastrin-Releasing Peptide; Humans; Pancreatic Hormones; Pancreatic Neoplasms; Parasympatholytics; Peptides; Piperidines; Pirenzepine; Receptors, Muscarinic; Sincalide; Tumor Cells, Cultured | 1991 |
Study of the muscarinic receptor subtypes in N1E 115 mouse neuroblastoma cells.
Topics: Animals; Carbachol; Cyclic AMP; Cyclic GMP; Indicators and Reagents; Ligands; Mice; Neuroblastoma; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tumor Cells, Cultured | 1991 |
M3 muscarinic cholinoceptors are linked to phosphoinositide metabolism in rat cerebellar granule cells.
Topics: Animals; Animals, Newborn; Binding, Competitive; Carbachol; Cerebellum; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Parasympatholytics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured human retinal pigment epithelium cells.
Topics: Adult; Atropine; Carbachol; Cells, Cultured; Dose-Response Relationship, Drug; Humans; Inositol Phosphates; Pertussis Toxin; Phosphatidylinositols; Pigment Epithelium of Eye; Pirenzepine; Receptors, Muscarinic; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Virulence Factors, Bordetella | 1991 |
The Na+, K(+)-ATPase inhibitor ouabain and the Na+ ionophore monensin have opposite effects upon carbachol-stimulated inositol phospholipid breakdown in rat cerebral cortical miniprisms.
Topics: Animals; Buffers; Carbachol; Cerebral Cortex; Inulin; Monensin; Ouabain; Phosphatidylinositols; Pirenzepine; Potassium; Rats; Sodium; Sodium-Potassium-Exchanging ATPase | 1991 |
Differential coupling of muscarinic receptors to Ca2+ mobilization and cyclic AMP in SH-SY5Y and IMR 32 neuroblastoma cells.
Topics: Acetylcholine; Alprostadil; Atropine; Calcium; Carbachol; Cyclic AMP; Humans; Methacholine Chloride; Muscarine; Neuroblastoma; Pertussis Toxin; Pirenzepine; Receptors, Muscarinic; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Muscarinic receptor-linked elevation of cAMP in SH-SY5Y neuroblastoma cells is mediated by Ca2+ and protein kinase C.
Topics: Adenylate Cyclase Toxin; Alprostadil; Calcium; Carbachol; Cholera Toxin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Neuroblastoma; Pertussis Toxin; Pirenzepine; Protein Kinase C; Receptors, Muscarinic; Second Messenger Systems; Signal Transduction; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1991 |
Central muscarinic receptor subtypes and carrageenin-induced paw oedema in rats.
Topics: Animals; Arecoline; Carbachol; Carrageenan; Cerebellum; Corpus Striatum; Edema; Female; Foot; Gallamine Triethiodide; Inflammation; Male; Oxotremorine; Pirenzepine; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1991 |
Sialic acid residues as catalysts for M2-muscarinic agonist-receptor interactions.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cell Membrane; Kinetics; Male; Myocardium; Neuraminidase; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Sialic Acids | 1990 |
Rat hippocampal muscarinic autoreceptors are similar to the M2 (cardiac) subtype: comparison with hippocampal M1, atrial M2 and ileal M3 receptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Electric Stimulation; Hippocampus; Ileum; Inositol Phosphates; Male; Myocardium; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synapses | 1990 |
Pre- and postjunctional muscarinic receptors in canine bronchi.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol Compounds; Bronchi; Carbachol; Dogs; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1990 |
Selective inhibition of responses to carbachol and McN-A-343 in the rabbit vas deferens.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bis-Trimethylammonium Compounds; Carbachol; Cocaine; Electric Stimulation; In Vitro Techniques; Isoindoles; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pancuronium; Pirenzepine; Rabbits; Vas Deferens | 1990 |
Muscarinic regulation of cyclic AMP metabolism in rat neostriatal cultures.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cells, Cultured; Corpus Striatum; Cyclic AMP; Embryo, Mammalian; Kinetics; N-Methylscopolamine; Neurons; Parasympatholytics; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Carbachol activates a novel sodium current in isolated guinea pig ventricular myocytes via M2 muscarinic receptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Cells, Cultured; Electric Conductivity; GTP-Binding Proteins; Guinea Pigs; Heart; In Vitro Techniques; Myocardium; Pertussis Toxin; Pirenzepine; Receptors, Muscarinic; Sodium; Virulence Factors, Bordetella | 1991 |
Effect of temperature reduction on responsiveness to cholinomimetics in the taenia caeci of the guinea-pig.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Colon; Drug Interactions; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Kinetics; Muscle Contraction; Parasympathomimetics; Phenoxybenzamine; Pirenzepine; Propylbenzilylcholine Mustard; Quinuclidinyl Benzilate; Temperature | 1991 |
Evidence for facilitatory and inhibitory muscarinic receptors on postganglionic sympathetic nerves in mouse isolated atria.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Cocaine; Diamines; Dicyclomine; Female; Heart; Hexamethonium Compounds; In Vitro Techniques; Mice; Myocardium; Nerve Endings; Neurons; Norepinephrine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Sympathetic Nervous System; Synaptic Transmission | 1991 |
Functional subtyping of muscarinic receptors on canine esophageal mucosa.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Amiloride; Animals; Atropine; Carbachol; Chlorides; Dogs; Electric Conductivity; Esophagus; Female; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Mucous Membrane; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Sodium | 1991 |
Presynaptic M2-muscarinic receptors on noradrenergic nerve endings and endothelium-derived M3 receptors in cat cerebral arteries.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Carbachol; Cats; Cerebral Arteries; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasodilation | 1991 |
Electrophysiological responses to muscarinic receptor stimulation in cultured hippocampal neurons.
Topics: Action Potentials; Animals; Atropine; Carbachol; Cells, Cultured; Electrophysiology; Female; Hippocampus; Kinetics; Membrane Potentials; Muscarine; Muscarinic Antagonists; Neurons; Parasympathomimetics; Pirenzepine; Pregnancy; Rats; Receptors, Muscarinic; Stimulation, Chemical | 1991 |
Age-dependent decrease in the affinity of muscarinic M1 receptors in neocortex of rhesus monkeys.
Topics: Aging; Animals; Autoradiography; Binding, Competitive; Carbachol; Cerebral Cortex; Kinetics; Macaca mulatta; Pirenzepine; Receptors, Muscarinic; Tritium | 1991 |
Regulation of muscarinic receptors by intrahippocampal injections of gallamine.
Topics: Animals; Autoradiography; Brain; Carbachol; Gallamine Triethiodide; Hippocampus; Injections; Male; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine | 1991 |
Acetylcholine receptors in dissociated nucleus basalis of Meynert neurons of the rat.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Membrane Potentials; Neurons; Nicotine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Substantia Innominata | 1991 |
Anti-muscarinic effect of alinidine on acetylcholine-induced vasodilation in isolated and perfused dog coronary arteries.
Topics: Acetylcholine; Animals; Carbachol; Clonidine; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Parasympatholytics; Piperidines; Pirenzepine; Vasodilation | 1991 |
The release of atrial natriuretic factor induced by central carbachol injection may be mediated by muscarinic M1 receptors.
Topics: Animals; Atrial Natriuretic Factor; Brain; Carbachol; Diamines; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Male; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Involvement of M1 and M2 muscarinic receptors of the basal forebrain in cholinergically mediated changes in the rat locomotion.
Topics: Animals; Atropine; Behavior, Animal; Brain; Carbachol; Hypothalamus, Anterior; Injections; Male; Motor Activity; Parasympathetic Nervous System; Pirenzepine; Preoptic Area; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Muscarinic responses of gastric parietal cells.
Topics: Aminopyrine; Animals; Arachidonic Acids; Calcium; Carbachol; Glucose; Image Processing, Computer-Assisted; Ionomycin; N-Methylscopolamine; Parasympatholytics; Parietal Cells, Gastric; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1991 |
Distribution and function of cholinergic receptors in the sheep detrusor muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Ganglia, Parasympathetic; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Piperidines; Pirenzepine; Receptors, Muscarinic; Sheep; Tetraisopropylpyrophosphamide; Urinary Bladder | 1991 |
Autoradiographic imaging of phosphoinositide turnover in the brain.
Topics: Alanine; Animals; Autoradiography; Brain; Carbachol; Cerebellum; Cycloleucine; Cytidine; Cytidine Diphosphate Diglycerides; Glutamates; Glutamic Acid; Hippocampus; Neomycin; Phosphatidylinositols; Pirenzepine; Purkinje Cells; Rats; Receptors, Muscarinic; Tissue Distribution | 1990 |
[Characterization of muscarinic acetylcholine receptors in the isolated gastric chief cells from guinea pig].
Topics: Animals; Carbachol; Cells, Cultured; Gastric Mucosa; Guinea Pigs; Pepsinogens; Pirenzepine; Receptors, Muscarinic | 1991 |
Characterization of muscarinic receptors in dog tracheal smooth muscle cells.
Topics: Animals; Atropine; Carbachol; Diamines; Dogs; In Vitro Techniques; Kinetics; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Trachea | 1991 |
Loss of high-affinity agonist binding to M1 muscarinic receptors in Alzheimer's disease: implications for the failure of cholinergic replacement therapies.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Carbachol; Choline O-Acetyltransferase; Female; Frontal Lobe; Humans; Kinetics; Male; Pirenzepine; Radioligand Assay; Receptors, Muscarinic | 1991 |
Effects of acetylcholine on different muscarinic receptors in the perfused porcine ear vein.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Ear; Feedback; Gallamine Triethiodide; Indomethacin; Muscarine; Muscle, Smooth, Vascular; Organ Culture Techniques; Perfusion; Pirenzepine; Receptors, Muscarinic; Swine; Vasomotor System | 1991 |
Activation of the pharmacologically defined M3 muscarinic receptor depolarizes hippocampal pyramidal cells.
Topics: Animals; Carbachol; Evoked Potentials; Hippocampus; In Vitro Techniques; Kinetics; Parasympatholytics; Piperidines; Pirenzepine; Pyramidal Tracts; Rats; Receptors, Muscarinic | 1990 |
Circadian rhythm in muscarinic receptor subtypes in rat forebrain.
Topics: Animals; Brain; Carbachol; Circadian Rhythm; In Vitro Techniques; Kinetics; Male; N-Methylscopolamine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Promiscuous or heterogeneous muscarinic receptors in rat atria? II. Antagonism of responses to carbachol by pirenzepine.
Topics: Animals; Atrial Function; Carbachol; Drug Interactions; Heart; Heart Atria; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; Myocardial Contraction; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1990 |
Differential coupling between muscarinic receptors and G-proteins in regions of the rat brain.
Topics: Animals; Brain; Carbachol; Cerebral Cortex; Corpus Striatum; GTP Phosphohydrolases; GTP-Binding Proteins; Hippocampus; Kinetics; Male; Pirenzepine; Rats; Receptors, Muscarinic; Rhombencephalon | 1990 |
Pharmacological evidence for distinct muscarinic receptor subtypes coupled to the inhibition of adenylate cyclase and to the increased generation of inositol phosphates in the guinea pig myometrium.
Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Myometrium; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Type C Phospholipases; Uterine Contraction | 1990 |
Muscarinic M3 receptors are coupled to two signal transduction pathways in rat submandibular cells.
Topics: Animals; Atropine; Carbachol; Cyclic AMP; Parasympatholytics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Signal Transduction; Submandibular Gland | 1990 |
Evidence that a guanine nucleotide-binding protein linked to a muscarinic receptor inhibits directly phospholipase C.
Topics: Alkaloids; Animals; Atropine; Calcimycin; Calcium; Carbachol; Cell Line; Cell Membrane Permeability; Colforsin; Cyclic AMP; Cytosol; GTP-Binding Proteins; Guanosine Triphosphate; Inositol Phosphates; Kinetics; Norepinephrine; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Staurosporine; Type C Phospholipases; Virulence Factors, Bordetella | 1990 |
On the involvement of multiple muscarinic receptor subtypes in the activation of phosphoinositide metabolism in rat cerebral cortex.
Topics: Alkylating Agents; Animals; Binding, Competitive; Carbachol; Cell Aggregation; Cerebral Cortex; Inositol Phosphates; Kinetics; Male; Phosphatidylinositols; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1990 |
Amplification of the rat M2 muscarinic receptor gene by the polymerase chain reaction: functional expression of the M2 muscarinic receptor.
Topics: Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Carbachol; Cell Line; Cloning, Molecular; Cyclic AMP; Fibroblasts; Furans; Gene Amplification; Gene Expression; Molecular Sequence Data; Muscarinic Antagonists; Naphthalenes; Phosphatidylinositols; Piperidines; Pirenzepine; Plasmids; Polymerase Chain Reaction; Rats; Receptors, Muscarinic; Transfection | 1990 |
Differential enhancement by potassium ions of M1-type and M2-type muscarinic receptor-mediated phosphoinositide breakdown in the rat brain.
Topics: Animals; Carbachol; Corpus Striatum; Female; Frontal Lobe; Male; Phosphatidylinositols; Pirenzepine; Potassium; Rats; Receptors, Muscarinic | 1990 |
Muscarinic acetylcholine receptor subtypes which selectively couple to phospholipase C: pharmacological and biochemical properties.
Topics: Animals; Atropine; Carbachol; Cell Line; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Inositol Phosphates; Ligands; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Tritium; Type C Phospholipases | 1990 |
Strong and persistent activation of inositol lipid breakdown induces early mitogenic events but not Go to S phase progression in hamster fibroblasts. Comparison of thrombin and carbachol action in cells expressing M1 muscarinic acetylcholine receptors.
Topics: Adenylate Cyclase Toxin; Animals; Atropine; Calcium; Carbachol; Cell Cycle; Cell Line; Clone Cells; Cricetinae; Cricetulus; DNA Replication; Fibroblasts; Inositol; Inositol Phosphates; Kinetics; Lung; Pertussis Toxin; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Pirenzepine; Proto-Oncogenes; Receptors, Muscarinic; Resting Phase, Cell Cycle; S Phase; Thrombin; Transfection; Virulence Factors, Bordetella | 1990 |
Cholinergic agonists increase cell calcium in rat medullary collecting tubules. A fura-2 study.
Topics: Acetylcholine; Animals; Atropine; Calcium; Carbachol; Fluorescent Dyes; Fura-2; Kidney Medulla; Kidney Tubules, Collecting; Male; Microscopy, Fluorescence; Pirenzepine; Rats; Receptors, Muscarinic | 1990 |
Human gastric mucosa expresses glandular M3 subtype of muscarinic receptors.
Topics: Carbachol; Gastric Mucosa; Humans; In Vitro Techniques; N-Methylscopolamine; Parasympatholytics; Piperazines; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Binding characteristics of the muscarinic receptor subtype in rabbit pancreas.
Topics: Animals; Binding, Competitive; Carbachol; Kinetics; Muscarine; Oxotremorine; Pancreas; Parasympathomimetics; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Time Factors; Tritium | 1990 |
Specificity of methoctramine in blocking muscarinic receptors which inhibit adenylate cyclase in cerebellar granule cells.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Cells, Cultured; Cerebellum; Diamines; Hydrolysis; Parasympatholytics; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1990 |
Presynaptic M1 muscarinic cholinoceptors mediate inhibition of excitatory synaptic transmission in the hippocampus in vitro.
Topics: Action Potentials; Animals; Carbachol; Cholinergic Fibers; Hippocampus; In Vitro Techniques; Male; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1990 |
Muscarinic receptors mediating the positive inotropic effect of carbachol in embryonic chick ventricle have a low affinity for pirenzepine.
Topics: Animals; Carbachol; Cardiotonic Agents; Chick Embryo; Dose-Response Relationship, Drug; Heart; Heart Ventricles; Myocardial Contraction; Pirenzepine; Receptors, Muscarinic; Stimulation, Chemical | 1990 |
Endogenous aspartate release in the rat hippocampus is inhibited by M2 'cardiac' muscarinic receptors.
Topics: Acetylcholine; Animals; Aspartic Acid; Calcium; Carbachol; Chromatography, High Pressure Liquid; Heart; Hippocampus; In Vitro Techniques; Male; Myocardium; Neuromuscular Depolarizing Agents; Oxotremorine; Pirenzepine; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1990 |
Muscarinic receptor subtypes mediating negative chrono- and inotropic responses in isolated, blood-perfused dog right atria.
Topics: Animals; Atropine; Carbachol; Cardiotonic Agents; Dogs; Electric Stimulation; Female; Heart Atria; Male; Myocardial Contraction; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Vagus Nerve | 1990 |
Interaction of chronic ethanol consumption and aging on brain muscarinic cholinergic receptors.
Topics: Aging; Animals; Binding Sites; Brain; Carbachol; Ethanol; Male; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cholinergic | 1990 |
Carbachol-induced potentiation and inhibition of acid secretion by guinea pig gastric gland.
Topics: Aminopyrine; Animals; Atropine; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Gastric Acid; Gastric Mucosa; Guinea Pigs; Histamine; In Vitro Techniques; Male; N-Methylscopolamine; Parasympathomimetics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Muscarinic suppression of the evoked N-wave by oxotremorine-M recorded in the guinea-pig olfactory cortex slice.
Topics: Action Potentials; Animals; Carbachol; Cerebral Cortex; Diamines; Electric Stimulation; Electroencephalography; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Olfactory Bulb; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pirenzepine; Receptors, Muscarinic | 1990 |
Selective antagonists provide evidence that M1 muscarinic receptors may mediate carbachol-induced drinking in the rat.
Topics: Angiotensin II; Animals; Carbachol; Dose-Response Relationship, Drug; Drinking; Injections, Intraventricular; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1990 |
Down-regulation of muscarinic receptors in the striatum of organophosphate-treated swine.
Topics: Acetylcholinesterase; Animals; Binding Sites; Binding, Competitive; Carbachol; Corpus Striatum; Down-Regulation; Guanylyl Imidodiphosphate; Isoflurophate; Magnesium; Male; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Receptors, Muscarinic; Regression Analysis; Swine | 1990 |
Effects of aging on nicotinic and muscarinic autoreceptor function in the rat brain: relationship to presynaptic cholinergic markers and binding sites.
Topics: Acetylcholine; Aging; Animals; Brain; Carbachol; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Hippocampus; Male; Muscarinic Antagonists; Nicotinic Antagonists; Parasympatholytics; Pirenzepine; Rats; Receptors, Muscarinic; Receptors, Nicotinic; Synapses; Thalamus | 1990 |
Comparative inhibitory effects of pirenzepine and atropine on cholinergic stimulation of exocrine and endocrine rat pancreas.
Topics: Amylases; Animals; Atropine; Benzodiazepinones; Carbachol; In Vitro Techniques; Insulin; Insulin Secretion; Islets of Langerhans; Male; Pancreas; Pancreatic Juice; Parasympatholytics; Parasympathomimetics; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1985 |
Regional differences in the coupling of muscarinic receptors to inositol phospholipid hydrolysis in guinea pig brain.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Brain; Carbachol; Corpus Striatum; Guinea Pigs; Hydrolysis; Oxotremorine; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Time Factors; Tissue Distribution | 1985 |
A cholinergic antagonist identifies a subclass of muscarinic receptors in isolated rat pancreatic acini.
Topics: Amylases; Animals; Atropine; Carbachol; Cerebral Cortex; Dose-Response Relationship, Drug; Kinetics; Male; Myocardium; N-Methylscopolamine; Pancreas; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
Biphasic release of endothelium-derived relaxing factor(s) by acetylcholine from perfused canine femoral arteries. Characterization of muscarinic receptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Carbachol; Dogs; Endothelium; Female; Femoral Artery; In Vitro Techniques; Male; Nitric Oxide; Pirenzepine; Receptors, Muscarinic; Vasodilator Agents | 1987 |
Pirenzepine inhibits pancreatic exocrine secretion in the rat.
Topics: Amylases; Animals; Carbachol; In Vitro Techniques; Male; Pancreas; Pancreatic Juice; Pirenzepine; Protein Biosynthesis; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Stimulation, Chemical | 1986 |
Muscarinic receptors activate calcium channels and calcium dependent potassium channels in NlE-115 neuroblastoma cells.
Topics: Animals; Calcium; Calcium Channel Blockers; Carbachol; Clone Cells; In Vitro Techniques; Ion Channels; Membrane Potentials; Mice; Neuroblastoma; Neurons; Pirenzepine; Potassium; Receptors, Muscarinic | 1987 |
Involvement of M1-muscarinic receptors in the excitation of neocortical neurones by acetylcholine.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Carbachol; Cerebral Cortex; Male; Neurons; Nicotine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Time Factors | 1987 |
Muscarinic receptors on nerves and muscles in opossum esophagus muscularis mucosa.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Electric Stimulation; Esophagus; In Vitro Techniques; Mucous Membrane; Muscle Contraction; Muscle, Smooth; Neurons; Opossums; Parasympatholytics; Pirenzepine; Receptors, Muscarinic | 1987 |
Intracellular calcium homeostasis in a human neuroblastoma cell line: modulation by depolarization, cholinergic receptors, and alpha-latrotoxin.
Topics: Aminoquinolines; Arthropod Venoms; Atropine; Calcimycin; Calcium; Carbachol; Cytoplasm; Egtazic Acid; Fluorescent Dyes; Homeostasis; Humans; Ion Channels; Membrane Potentials; Neuroblastoma; Pirenzepine; Potassium Chloride; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Spectrometry, Fluorescence; Spider Venoms; Tumor Cells, Cultured; Verapamil | 1988 |
The muscarinic receptor of rat pituitary GH3 cells is coupled with adenylate cyclase inhibition, but not with phosphoinositide turnover.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Carbachol; Inositol Phosphates; N-Methylscopolamine; Phosphatidylinositols; Pirenzepine; Pituitary Gland; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Thyrotropin-Releasing Hormone; Tumor Cells, Cultured | 1988 |
Regulation of histamine release and synthesis in the brain by muscarinic receptors.
Topics: Animals; Brain; Carbachol; Histamine Release; Male; Oxotremorine; Pirenzepine; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1989 |
Effect of a new cholinergic agonist, aclatonium napadisilate, on exocrine and endocrine rat pancreas.
Topics: Acetylcholine; Amylases; Animals; Carbachol; In Vitro Techniques; Insulin; Insulin Secretion; Male; Pancreas; Pancreatic Juice; Parasympathomimetics; Pirenzepine; Proglumide; Proteins; Rats; Rats, Inbred Strains | 1989 |
Rostral ventrolateral medulla muscarinic receptor involvement in central ventilatory chemosensitivity.
Topics: Animals; Atropine; Blood Pressure; Carbachol; Carbon Dioxide; Cats; Female; Male; Medulla Oblongata; Phrenic Nerve; Pirenzepine; Receptors, Muscarinic; Reference Values; Respiration; Vagotomy | 1989 |
Carbachol and pirenzepine discriminate effects mediated by two muscarinic receptor subtypes on hippocampal neurons in vitro.
Topics: Acetylcholine; Action Potentials; Animals; Carbachol; Hippocampus; In Vitro Techniques; Kinetics; Neurons; Pirenzepine; Receptors, Muscarinic | 1989 |
Cholinergic activation of medial pontine reticular formation neurons in vitro.
Topics: Acetylcholine; Animals; Brain Stem; Carbachol; Cesium; Chlorides; Electric Conductivity; In Vitro Techniques; Kinetics; Membrane Potentials; Neurons; Pirenzepine; Pons; Rats; Rats, Inbred Strains; Reticular Formation; Synapses; Tetrodotoxin | 1989 |
Different agonist-receptor active conformations for rat brain M1 and M2 muscarinic receptors that are separately coupled to two biochemical effector systems.
Topics: Animals; Brain; Carbachol; Cyclic AMP; In Vitro Techniques; Male; Phosphatidylinositols; Pirenzepine; Protein Conformation; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1989 |
Cholinergic stimulation of phosphoinositide hydrolysis in the rat pineal gland.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Ganglionectomy; Inositol Phosphates; Male; Norepinephrine; Parasympathetic Nervous System; Phosphatidylinositols; Pineal Gland; Pirenzepine; Rats; Rats, Inbred Strains | 1989 |
Pineal muscarinic phosphoinositide response: pertussis toxin resistant signaling with very low receptor number.
Topics: Animals; Atropine; Carbachol; Male; Norepinephrine; Organ Culture Techniques; Pertussis Toxin; Phosphatidylinositols; Pineal Gland; Pirenzepine; Prazosin; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Signal Transduction; Virulence Factors, Bordetella | 1989 |
Human HT-29 colon carcinoma cells contain muscarinic M3 receptors coupled to phosphoinositide metabolism.
Topics: Carbachol; Carcinoma; Colonic Neoplasms; Gastric Mucosa; Humans; Inositol Phosphates; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Tumor Cells, Cultured | 1989 |
Potentiation and suppression by eserine of muscarinic synaptic transmission in the guinea-pig hippocampal slice.
Topics: Action Potentials; Animals; Atropine; Carbachol; Guinea Pigs; Hippocampus; In Vitro Techniques; Neurons; Physostigmine; Pirenzepine; Synapses; Synaptic Transmission | 1989 |
Evidence for the coupling of muscarinic M1 receptors to polyphosphoinositide turnover in rat cortical synaptosomes.
Topics: Animals; Carbachol; Cerebellum; Cerebral Cortex; In Vitro Techniques; Male; Phosphatidylinositol Phosphates; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes; Trihexyphenidyl | 1989 |
Interaction acetylcholine-glutamate in rat hippocampus: involvement of two subtypes of M-2 muscarinic receptors.
Topics: Acetylcholine; Animals; Carbachol; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1989 |
Pirenzepine distinguishes between muscarinic receptor-mediated phosphoinositide breakdown and inhibition of adenylate cyclase.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adenylyl Cyclase Inhibitors; Animals; Atropine; Benzodiazepinones; Brain; Carbachol; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Myocardium; Oxotremorine; Parotid Gland; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1985 |
The putative M1 muscarinic receptor does not regulate phosphoinositide hydrolysis. Studies with pirenzepine and McN-A343 in chick heart and astrocytoma cells.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Astrocytoma; Benzodiazepinones; Carbachol; Cells, Cultured; Chick Embryo; Hydrolysis; Myocardium; Parasympatholytics; Phosphatidylinositols; Pirenzepine; Pyrrolidines; Quaternary Ammonium Compounds; Receptors, Muscarinic | 1985 |
The interaction of McN-A-343 with pirenzepine and other selective muscarine receptor antagonists at a prejunctional muscarine receptor.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Alkaloids; Animals; Atropine; Benzodiazepinones; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; In Vitro Techniques; Pancuronium; Pirenzepine; Quaternary Ammonium Compounds; Rabbits; Receptors, Muscarinic | 1985 |
Agonist binding to M1 muscarinic receptors is sensitive to guanine nucleotides.
Topics: Animals; Carbachol; Guanine Nucleotides; Guanylyl Imidodiphosphate; In Vitro Techniques; Indicators and Reagents; Kinetics; Male; Methacholine Compounds; Oxotremorine; Pilocarpine; Pirenzepine; Rabbits; Receptors, Muscarinic; Second Messenger Systems | 1989 |
Carbachol depresses synaptic responses in the medial but not the lateral perforant path.
Topics: Action Potentials; Animals; Atropine; Carbachol; Electric Stimulation; Guinea Pigs; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Pirenzepine; Time Factors | 1989 |
Increases in muscarinic stimulated hydrolysis of inositol phospholipids in rat hippocampus following cholinergic deafferentation are not parallelled by alterations in cholinergic receptor density.
Topics: Animals; Carbachol; Cholinergic Fibers; Hippocampus; Inositol; Male; Nicotine; Phospholipids; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1989 |
Identification and characterization of muscarinic receptors in cultured human pancreatic carcinoma cells.
Topics: Atropine; Carbachol; Cell Line; Humans; Inositol Phosphates; Kinetics; N-Methylscopolamine; Pancreatic Neoplasms; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured | 1989 |
Muscarinic receptor binding characteristics of a human neuroblastoma SK-N-SH and its clones SH-SY5Y and SH-EP1.
Topics: Arecoline; Atropine; Carbachol; Cell Membrane; Humans; Neuroblastoma; Piperidines; Pirenzepine; Receptors, Muscarinic; Tumor Cells, Cultured | 1989 |
Pharmacologic discrimination between receptor heterogeneity and allosteric interaction: resultant analysis of gallamine and pirenzepine antagonism of muscarinic responses in rat trachea.
Topics: Allosteric Regulation; Animals; Atropine; Binding Sites; Carbachol; Dose-Response Relationship, Drug; Gallamine Triethiodide; In Vitro Techniques; Male; Muscarine; Oxotremorine; Parasympatholytics; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine; Trachea | 1989 |
Binding characteristics of the muscarinic receptor subtype of the NG108-15 cell line.
Topics: Animals; Carbachol; Cell Membrane; Cerebral Cortex; Diamines; Humans; Myocardium; Pirenzepine; Rats; Receptors, Muscarinic; Submandibular Gland; Tumor Cells, Cultured; Virulence Factors, Bordetella | 1989 |
Presynaptic cholinergic mechanisms in the rat cerebellum: evidence for nicotinic, but not muscarinic autoreceptors.
Topics: Acetylcholine; Animals; Brain; Carbachol; Cerebellum; In Vitro Techniques; Kinetics; Ligands; Male; Parasympatholytics; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Receptors, Nicotinic | 1989 |
Presynaptic muscarinic receptors in guinea pig superior cervical ganglion.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Ganglia, Sympathetic; Guinea Pigs; Oxotremorine; Pirenzepine; Receptors, Muscarinic; Synapses | 1989 |
The interaction of hexamethonium with muscarinic receptor subtypes in vitro.
Topics: Animals; Carbachol; Diamines; Guinea Pigs; Hexamethonium Compounds; In Vitro Techniques; Kinetics; Muscle Contraction; Muscle, Smooth, Vascular; Myocardium; N-Methylscopolamine; Pirenzepine; Potassium Chloride; Receptors, Muscarinic; Scopolamine Derivatives; Submandibular Gland | 1989 |
Stimulation of acid secretion and phosphoinositol production by rat parietal cell muscarinic M2 receptors.
Topics: Aminopyrine; Animals; Atropine; Binding, Competitive; Bucladesine; Carbachol; Gastric Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Parietal Cells, Gastric; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Sugar Phosphates | 1988 |
Muscarinic receptor-mediated phosphoinositide hydrolysis in the rat retina.
Topics: Adenylyl Cyclases; Animals; Atropine; Carbachol; Hydrolysis; In Vitro Techniques; Male; Phosphatidylinositols; Physostigmine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Retina | 1988 |
Calcium-dependent pirenzepine-sensitive muscarinic response in the rat hippocampal slice.
Topics: Animals; Calcium; Carbachol; Hippocampus; In Vitro Techniques; Membrane Potentials; Oxotremorine; Parasympathomimetics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Pirenzepine; Rats; Receptors, Muscarinic | 1988 |
Muscarinic receptor coupling to inositol phospholipid metabolism in guinea-pig cerebral cortex, parotid gland and ileal smooth muscle.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Guanosine Triphosphate; Guinea Pigs; Ileum; Muscle, Smooth; N-Methylscopolamine; Oxotremorine; Parotid Gland; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Pseudo-noncompetitive antagonism of muscarinic receptor-mediated cyclic GMP formation and phosphoinositide hydrolysis by pirenzepine.
Topics: Animals; Atropine; Carbachol; Cyclic GMP; Hydrolysis; Mice; N-Methylscopolamine; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Second-messenger generation in PC12 cells. Interactions between cyclic AMP and Ca2+ signals.
Topics: Animals; Calcium; Carbachol; Cell Differentiation; Cell Line; Clonidine; Cyclic AMP; Imidazoles; Nerve Growth Factors; Phenylisopropyladenosine; Pheochromocytoma; Pirenzepine; Rats; Tumor Cells, Cultured | 1988 |
Pirenzepine-sensitive muscarinic receptors regulate gastric somatostatin and gastrin.
Topics: Animals; Atropine; Benzodiazepinones; Carbachol; Dose-Response Relationship, Drug; Gastric Mucosa; Gastrins; Male; Pirenzepine; Radioimmunoassay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Somatostatin; Stimulation, Chemical | 1985 |
Desensitization of muscarinic acetylcholine receptors: possible relation to receptor heterogeneity and phosphoinositides.
Topics: Acetylcholine; Animals; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Carbachol; Hippocampus; Male; Molecular Conformation; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1986 |
AF-DX 116, a cardioselective muscarinic antagonist.
Topics: Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Cats; Dimethylphenylpiperazinium Iodide; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Gastric Acid; Gastric Emptying; Guinea Pigs; Heart; Heart Rate; Male; Muscarine; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Pirenzepine; Rats; Receptors, Muscarinic | 1987 |
Functional and direct binding studies using subtype selective muscarinic receptor antagonists.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Dicyclomine; Diphenylacetic Acids; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Myocardium; Phenethylamines; Phenylacetates; Pirenzepine; Receptors, Muscarinic | 1988 |
Muscarinic cholinergic receptor subtype on frog esophageal peptic cells: binding and secretion studies.
Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Esophagus; Imipramine; Kinetics; N-Methylscopolamine; Oxotremorine; Pepsinogens; Pirenzepine; Propranolol; Radioligand Assay; Rana catesbeiana; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Effect of chronic nicotine treatment on nicotinic autoreceptor function and N-[3H]methylcarbamylcholine binding sites in the rat brain.
Topics: Acetylcholine; Animals; Brain; Calcium; Carbachol; Cerebral Cortex; Choline O-Acetyltransferase; Corpus Striatum; Frontal Lobe; Hippocampus; Kinetics; Male; Nicotine; Parietal Lobe; Pirenzepine; Potassium; Rats; Rats, Inbred Strains; Receptors, Nicotinic | 1989 |
State-dependent hypotonia in posterior cricoarytenoid muscles of the larynx caused by cholinoceptive reticular mechanisms.
Topics: Animals; Carbachol; Cats; Electromyography; Larynx; Male; Pirenzepine; Receptors, Cholinergic; Respiration; Respiratory Muscles; Sleep, REM | 1989 |
Muscarinic responses and binding in a murine neuroblastoma clone (N1E-115). Mediation of separate responses by high affinity and low affinity agonist-receptor conformations.
Topics: Animals; Benzodiazepinones; Carbachol; Clone Cells; Cyclic AMP; Cyclic GMP; Kinetics; Mice; N-Methylscopolamine; Neuroblastoma; Pirenzepine; Protein Conformation; Receptors, Muscarinic; Scopolamine Derivatives | 1985 |
Astrocytes have both M1 and M2 muscarinic receptor subtypes.
Topics: Animals; Astrocytes; Atropine; Benzodiazepinones; Carbachol; Cyclic AMP; Inositol; Isoproterenol; Phospholipids; Pirenzepine; Propranolol; Rats; Receptors, Muscarinic | 1986 |
Muscarinic cholinergic ligand binding to intact mouse pituitary tumor cells (AtT-20/D16-16) coupling with two biochemical effectors: adenylate cyclase and phosphatidylinositol turnover.
Topics: Adenylyl Cyclase Inhibitors; Animals; Atropine; Benzodiazepinones; Carbachol; Cells, Cultured; Cyclic AMP; Dose-Response Relationship, Drug; Kinetics; Mice; Phosphatidylinositols; Pirenzepine; Pituitary Neoplasms; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tritium | 1986 |
Potassium ion facilitation of phosphoinositide turnover activation by muscarinic receptor agonists in rat brain.
Topics: Animals; Benzodiazepinones; Carbachol; Dioxolanes; Hippocampus; Histamine; Male; Norepinephrine; Oxotremorine; Phosphatidylinositols; Pirenzepine; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1986 |
Carbachol-induced accumulation of inositol-1-phosphate in neurohybridoma NCB-20 cells: effects of lithium and phorbol esters.
Topics: Animals; Atropine; Benzodiazepinones; Brain; Carbachol; Cell Line; Chlorides; Cricetinae; Cricetulus; Embryo, Mammalian; Hybridomas; Inositol Phosphates; Lithium; Lithium Chloride; Mice; Neuroblastoma; Phorbol 12,13-Dibutyrate; Phorbol Esters; Pirenzepine; Sugar Phosphates; Tetradecanoylphorbol Acetate | 1986 |
Phosphatidylinositol response to cholinergic agonists in airway smooth muscle: relationship to contraction and muscarinic receptor occupancy.
Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Carbachol; Cattle; Chlorides; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; Lithium; Lithium Chloride; Membrane Lipids; Muscle Contraction; Muscle, Smooth; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Respiratory System; Trachea | 1986 |
Acute and chronic effects of ethanol on receptor-mediated phosphatidylinositol 4,5-bisphosphate breakdown in mouse brain.
Topics: Animals; Benzodiazepinones; Brain; Carbachol; Cerebral Cortex; Corpus Striatum; Ethanol; Hippocampus; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Pirenzepine; Receptors, Adrenergic, alpha; Receptors, Muscarinic | 1986 |
Slow cholinergic excitation of guinea pig hippocampal neurons is mediated by two muscarinic receptor subtypes.
Topics: Animals; Atropine; Benzodiazepinones; Carbachol; Cholinergic Fibers; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; Membrane Potentials; Pirenzepine; Receptors, Muscarinic; Synapses; Synaptic Transmission | 1986 |
Short-term desensitization of muscarinic cholinergic receptors in mouse neuroblastoma cells: selective loss of agonist low-affinity and pirenzepine high-affinity binding sites.
Topics: Benzodiazepinones; Carbachol; Cells, Cultured; Cyclic GMP; N-Methylscopolamine; Neuroblastoma; Pirenzepine; Protein Conformation; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1986 |
Muscarinic responses and binding in a murine neuroblastoma clone (N1E-115): cyclic GMP formation is mediated by a low affinity agonist-receptor conformation and cyclic AMP reduction is mediated by a high affinity agonist-receptor conformation.
Topics: Animals; Benzodiazepinones; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic GMP; N-Methylscopolamine; Neuroblastoma; Pirenzepine; Protein Conformation; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives | 1986 |
Effect of ethanol on receptor-stimulated phosphatidic acid and polyphosphoinositide metabolism in mouse brain.
Topics: Animals; Brain Chemistry; Carbachol; Ethanol; Histamine; Hydrolysis; Male; Mice; Mice, Inbred C57BL; Norepinephrine; Phosphatidic Acids; Phosphatidylinositol Phosphates; Phosphatidylinositols; Phosphorus Radioisotopes; Pirenzepine; Receptors, Muscarinic | 1986 |
Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured cerebellar granule cells: desensitization by receptor agonists.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Cerebellum; Kinetics; Male; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Virulence Factors, Bordetella | 1987 |
Solubilization with digitonin alters the kinetics of pirenzepine binding to muscarinic receptors from rat forebrain and heart.
Topics: Animals; Brain; Carbachol; Digitonin; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Kinetics; Male; Myocardium; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Solubility | 1987 |
Characteristics of canine lower esophageal sphincter: a new electrophysiological tool.
Topics: Animals; Carbachol; Cimetidine; Dogs; Electric Stimulation; Electrophysiology; Esophagus; Female; Histamine; In Vitro Techniques; Intercellular Junctions; Male; Microscopy, Electron; Muscle Contraction; Muscle, Smooth; Pirenzepine; Pyrilamine; Reference Values; Tetrodotoxin | 1988 |
Tetranitromethane modification of the muscarinic receptors in bovine adrenal medulla.
Topics: Adrenal Medulla; Animals; Atropine; Carbachol; Cattle; Dithiothreitol; In Vitro Techniques; Kinetics; Methane; Microsomes; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tetranitromethane | 1988 |
Characterization of muscarinic receptors in human pancreatic membranes.
Topics: Carbachol; Cell Membrane; Humans; Oxotremorine; Pancreas; Pilocarpine; Pirenzepine; Receptors, Muscarinic | 1988 |
An analysis of the depolarization produced in guinea-pig hippocampus by cholinergic receptor stimulation.
Topics: Animals; Atropine; Barium; Cadmium; Carbachol; Cesium; Dose-Response Relationship, Drug; Guinea Pigs; Hippocampus; In Vitro Techniques; Membrane Potentials; Pirenzepine; Potassium Channels; Receptors, Cholinergic; Serotonin | 1988 |
Characterization of cholinergic muscarinic receptors in the rabbit iris.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Ileum; Iris; Kinetics; Methacholine Chloride; Methacholine Compounds; Microsomes; N-Methylscopolamine; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Immunocytochemical and pharmacological evidence for an intrinsic cholinomimetic system modulating prolactin and growth hormone release in rat pituitary.
Topics: Acetylcholine; Animals; Atropine; Benztropine; Carbachol; Cells, Cultured; Choline O-Acetyltransferase; Dexamethasone; Female; Growth Hormone; Hemicholinium 3; Histocytochemistry; Immunoenzyme Techniques; Isoproterenol; Male; Naphthylvinylpyridine; Organ Culture Techniques; Pirenzepine; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Vasoactive Intestinal Peptide | 1988 |
Different binding properties of muscarinic M2-receptor subtypes for agonists and antagonists in porcine gastric smooth muscle and mucosa.
Topics: Animals; Binding Sites; Carbachol; Ethylmaleimide; Gastric Mucosa; Muscle, Smooth; Pirenzepine; Receptors, Muscarinic; Swine | 1988 |
Differentiation of muscarinic cholinergic receptor subtypes in human cortex and pons: implications for anti-motion sickness therapy.
Topics: Carbachol; Cerebral Cortex; Humans; Motion Sickness; Pirenzepine; Pons; Quinuclidinyl Benzilate; Radioligand Assay; Receptors, Muscarinic; Scopolamine | 1988 |
Muscarinic stimulation of submucosal glands in swine trachea.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Exocrine Glands; Isoflurophate; Male; Mucus; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Scopolamine Derivatives; Swine; Trachea | 1988 |
Membrane depolarization and carbamoylcholine stimulate phosphatidylinositol turnover in intact nerve terminals.
Topics: Animals; Atropine; Calcium; Carbachol; Cerebral Cortex; In Vitro Techniques; Inositol Phosphates; Male; Membrane Potentials; Phosphatidylinositols; Pirenzepine; Potassium; Rats; Receptors, Muscarinic; Sugar Phosphates; Synaptosomes; Time Factors | 1988 |
Binding of muscarine receptor antagonists to pig coronary smooth muscle.
Topics: Animals; Atropine; Carbachol; Coronary Vessels; Heart Atria; In Vitro Techniques; Muscle, Smooth, Vascular; Piperazines; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Swine; Tritium | 1988 |
Agonist and antagonist binding of muscarinic acetylcholine receptors purified from porcine brain: interconversion of high- and low-affinity sites by sulfhydryl reagents.
Topics: Animals; Binding Sites; Binding, Competitive; Brain Chemistry; Carbachol; Centrifugation, Density Gradient; Disulfides; Dithionitrobenzoic Acid; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Guanosine Triphosphate; Oxidation-Reduction; Parasympathomimetics; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Sulfhydryl Compounds; Sulfhydryl Reagents; Swine | 1988 |
Differential alteration of various cholinergic markers in cortical and subcortical regions of human brain in Alzheimer's disease.
Topics: Acetylcholine; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Carbachol; Cerebral Cortex; Choline; Choline O-Acetyltransferase; Corpus Striatum; Female; Globus Pallidus; Hippocampus; Humans; Male; Middle Aged; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Substantia Innominata; Thalamus | 1988 |
The cloned murine M1 muscarinic receptor is associated with the hydrolysis of phosphatidylinositols in transfected murine B82 cells.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Cell Line; Cell Membrane; DNA, Recombinant; Fibroblasts; Guanylyl Imidodiphosphate; Hydrolysis; Mice; Muscarine; Nucleic Acid Hybridization; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Recombinant Proteins; Sequence Homology, Nucleic Acid; Transfection | 1988 |
Characterization of agonist and antagonist binding to muscarinic cholinergic receptors solubilized from rat cerebral cortex.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; In Vitro Techniques; Male; Oxotremorine; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Long-term atropine treatment lowers the efficacy of carbachol to stimulate phosphatidylinositol breakdown in the cerebral cortex and hippocampus of rats.
Topics: Animals; Atropine; Carbachol; Cell Membrane; Cerebral Cortex; Hippocampus; Inositol Phosphates; Male; Phosphatidylinositols; Pirenzepine; Potassium; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
A quantitative study of the effects of some muscarinic antagonists on the guinea-pig olfactory cortex slice.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Drug Interactions; Evoked Potentials; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Oxotremorine; Parasympathomimetics; Pirenzepine | 1988 |
Characterization of M1- and M2-muscarinic receptors in calf retina membranes.
Topics: Animals; Binding, Competitive; Carbachol; Cattle; Ethylmaleimide; Guanosine Triphosphate; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Retina | 1988 |
Pharmacological differences between two muscarinic responses of the rat superior cervical ganglion in vitro.
Topics: Acetylcholine; Animals; Atropine Derivatives; Calcium Chloride; Carbachol; Evoked Potentials; Ganglia, Spinal; In Vitro Techniques; Male; Muscarine; Neuromuscular Depolarizing Agents; Parasympatholytics; Pirenzepine; Rats; Receptors, Muscarinic | 1987 |
M2 muscarinic receptor subtype is associated with inositol trisphosphate accumulation, myosin light chain phosphorylation and contraction in sphincter smooth muscle of rabbit iris.
Topics: Animals; Atropine; Carbachol; Female; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Iris; Male; Muscle Contraction; Muscle, Smooth; Myosins; Phosphorylation; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Sugar Phosphates | 1987 |
Selectivity of partial agonists related to oxotremorine based on differences in muscarinic receptor reserve between the guinea pig ileum and urinary bladder.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Kinetics; Male; Mathematics; Oxotremorine; Pirenzepine; Pyrrolidines; Receptors, Muscarinic; Spasm; Structure-Activity Relationship; Urinary Bladder | 1987 |
Selectivity of pirenzepine in the central nervous system. III. Differential effects of multiple pirenzepine and scopolamine administrations on muscarinic receptors as measured autoradiographically.
Topics: Animals; Autoradiography; Binding, Competitive; Carbachol; Hippocampus; Male; Memory; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Time Factors | 1987 |
Characterization of the muscarinic receptor subtype in isolated gastric fundic cells of the rabbit.
Topics: Aminopyrine; Animals; Atropine; Carbachol; Gastric Fundus; Kinetics; Male; N-Methylscopolamine; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
Genetic influences on tolerance development with chronic oxotremorine infusion.
Topics: Animals; Behavior, Animal; Carbachol; Dose-Response Relationship, Drug; Drug Tolerance; Genotype; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tissue Distribution | 1987 |
Competitive inhibition of phosphoinositide hydrolysis by the muscarinic receptor antagonist AF-DX 116 is of low affinity in mouse cerebral cortex.
Topics: Animals; Carbachol; Cerebral Cortex; In Vitro Techniques; Inositol Phosphates; Male; Mice; Mice, Inbred C57BL; Pirenzepine; Receptors, Muscarinic; Sugar Phosphates | 1987 |
Different agonist binding properties of M1 and M2 muscarinic receptors in calf brain cortex membranes.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Cattle; Cell Membrane; Cerebral Cortex; Ethylmaleimide; Guanosine Triphosphate; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1987 |
Autoradiographic localization of muscarinic cholinergic receptors in visual areas of cat brain: variations in sensitivity of N-[3H]methylscopolamine binding sites to carbachol and pirenzepine.
Topics: Animals; Autoradiography; Brain; Carbachol; Cats; Male; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tritium; Visual Pathways | 1987 |
Comparison of muscarinic receptor properties in hatched chick heart atrium and ventricle.
Topics: Animals; Atropine; Benzodiazepinones; Carbachol; Chickens; Guanylyl Imidodiphosphate; Heart; In Vitro Techniques; Myocardial Contraction; Myocardium; Pirenzepine; Potassium; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tritium | 1986 |
[3H]pirenzepine and (-)-[3H]quinuclidinyl benzilate binding to rat cerebral cortical and cardiac muscarinic cholinergic sites. I. Characterization and regulation of agonist binding to putative muscarinic subtypes.
Topics: Acetylcholine; Animals; Benzodiazepinones; Buffers; Carbachol; Cerebral Cortex; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Myocardium; Parasympathomimetics; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tritium | 1986 |
Difference in effects of pirenzepine and atropine on carbachol-induced pepsinogen secretion from isolated gastric glands.
Topics: Animals; Atropine; Benzodiazepinones; Carbachol; Dose-Response Relationship, Drug; Drug Synergism; Gastric Mucosa; Guinea Pigs; Pepsinogens; Pirenzepine; Receptors, Muscarinic | 1986 |
Muscarinic M2-receptors enhance polyphosphoinositol release in rat gastric mucosal cells.
Topics: Aminopyrine; Animals; Atropine; Benzodiazepinones; Binding, Competitive; Carbachol; Drug Synergism; Gastric Mucosa; Inositol Phosphates; Pirenzepine; Rats; Receptors, Muscarinic; Sugar Phosphates | 1986 |
Effects of N-ethylmaleimide on muscarinic acetylcholine receptor subtype autoradiography and inositide response in rat brain.
Topics: Animals; Autoradiography; Benzodiazepinones; Brain; Carbachol; Ethylmaleimide; In Vitro Techniques; Male; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Cholinergic | 1986 |
Copper-induced alteration of muscarinic binding in bovine adrenal medulla.
Topics: Adrenal Medulla; Animals; Atropine; Carbachol; Cattle; Copper; In Vitro Techniques; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1986 |
Identification of M2 muscarinic receptors in membranes from bovine cerebral basal arteries.
Topics: Animals; Carbachol; Cattle; Cerebral Arteries; Cerebral Cortex; Ethylmaleimide; Guanosine Triphosphate; Membranes; Myocardium; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1986 |
Muscarinic receptor-stimulated Ca2+ signaling and inositol lipid metabolism in avian salt gland cells.
Topics: Aminoquinolines; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Ducks; Inositol Phosphates; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Salt Gland; Sugar Phosphates | 1986 |
Pharmacologic characterization and functional role of muscarinic autoreceptors in the rabbit striatum.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Corpus Striatum; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Oxotremorine; Physostigmine; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine; Time Factors | 1987 |
Characterization of high affinity [3H]pirenzepine and (-)-[3H] quinuclidinyl benzilate binding to muscarinic cholinergic receptors in rabbit peripheral lung.
Topics: Animals; Binding, Competitive; Carbachol; Female; Guanylyl Imidodiphosphate; Kinetics; Lung; Male; Myocardium; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Stereoisomerism | 1987 |
Carbachol changes spike-generation properties of GH3 pituitary cells.
Topics: Action Potentials; Carbachol; Cell Line; Pirenzepine; Pituitary Gland | 1987 |
Determination of the muscarinic receptor subtype mediating vasodilatation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atropine; Benzodiazepinones; Carbachol; Dogs; Female; Femoral Artery; Gallamine Triethiodide; In Vitro Techniques; Male; Pancuronium; Parasympatholytics; Phenethylamines; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Vasodilation | 1985 |
Heterogeneity of muscarinic cholinergic receptors in the developing chick embryo retina.
Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Carbachol; Chick Embryo; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Retina; Synapses | 1985 |
Muscarinic acetylcholine receptors in chick heart: influence of heat and N-ethylmaleimide on receptor conformations and interactions with guanine nucleotide-dependent regulatory proteins.
Topics: Animals; Benzodiazepinones; Carbachol; Chick Embryo; Ethylmaleimide; Heart; Hot Temperature; Molecular Conformation; Myocardium; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1985 |
Muscarinic receptor subclasses in the chick embryo retina: influence of corticosterone treatment.
Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Carbachol; Chick Embryo; Corticosterone; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Retina | 1985 |
Characterization of [3H]pirenzepine binding to muscarinic cholinergic receptors solubilized from rat brain.
Topics: Animals; Benzodiazepinones; Binding Sites; Brain; Carbachol; Detergents; In Vitro Techniques; Kinetics; Male; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Solubility; Tritium | 1985 |
Pirenzepine indicates heterogeneity of muscarinic receptors linked to cerebral inositol phospholipid metabolism.
Topics: Animals; Atropine; Benzodiazepinones; Brain; Carbachol; Cerebral Cortex; In Vitro Techniques; Inositol; Inositol Phosphates; Medulla Oblongata; Pirenzepine; Pons; Rats; Receptors, Muscarinic; Stimulation, Chemical | 1985 |
Carbachol stimulation of phosphatidic acid synthesis: competitive inhibition by pirenzepine in synaptosomes from rat cerebral cortex.
Topics: Animals; Benzodiazepinones; Carbachol; Cerebral Cortex; Male; Phosphatidic Acids; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1985 |
On the presence in the cerebral cortex of muscarinic receptor subtypes which differ in neuronal localization, function and pharmacological properties.
Topics: Acetylcholine; Animals; Atropine; Benzodiazepinones; Carbachol; Cerebral Cortex; Dicyclomine; Dopamine; Drug Synergism; Neurons; Phenethylamines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1985 |
Pharmacological distinction between two muscarinic responses on the isolated superior cervical ganglion of the rat.
Topics: Animals; Atropine Derivatives; Benzodiazepinones; Calcium Chloride; Carbachol; Evoked Potentials; Gallamine Triethiodide; Ganglia, Spinal; In Vitro Techniques; Muscarine; Pirenzepine; Rats; Receptors, Muscarinic | 1985 |
[Inhibitory effects of pirenzepine on cholinergic stimulation of exocrine rat pancreas in vitro].
Topics: Animals; Benzodiazepinones; Carbachol; In Vitro Techniques; Male; Pancreas; Parasympatholytics; Pirenzepine; Rats; Rats, Inbred Strains | 1985 |
Pirenzepine (LS 519): a weak inhibitor of acid secretion by isolated rat parietal cells.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Atropine; Benzodiazepinones; Bucladesine; Carbachol; Gastric Acid; Gastric Mucosa; Histamine; In Vitro Techniques; Pirenzepine; Rats | 1982 |
Quantitative receptor autoradiography: application to the characterization of multiple receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Autoradiography; Benzodiazepinones; Binding, Competitive; Brain; Carbachol; Hippocampus; Indoles; Oxotremorine; Pindolol; Pirenzepine; Rats; Receptors, Muscarinic; Receptors, Serotonin; Superior Colliculi; Tetrahydronaphthalenes | 1984 |
Cellular origin and release of intrinsic factor from isolated rat gastric mucosal cells.
Topics: Aminopyrine; Animals; Atropine; Benzodiazepinones; Carbachol; Carbon Radioisotopes; Cobalt Radioisotopes; Female; Gastrointestinal Agents; Intrinsic Factor; Kinetics; Parietal Cells, Gastric; Pepsin A; Pirenzepine; Rats; Rats, Inbred Strains; Subcellular Fractions | 1983 |
Anti-ulcer and secretion-inhibitory properties of the tricyclic derivative doxepin in rats and dogs.
Topics: Animals; Anti-Inflammatory Agents; Anti-Ulcer Agents; Benzodiazepinones; Carbachol; Cimetidine; Depression, Chemical; Dogs; Doxepin; Duodenal Ulcer; Female; Gastric Mucosa; Gastrointestinal Motility; Humans; Injections, Intraperitoneal; Male; Pentagastrin; Pirenzepine; Rats; Rats, Inbred Strains; Salivation; Serotonin Antagonists; Species Specificity; Stress, Psychological | 1984 |
Pharmacological evidence for cardiac muscarinic receptor subtypes.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzodiazepinones; Binding Sites; Butylscopolammonium Bromide; Carbachol; Female; Guinea Pigs; Heart Rate; Male; Myocardial Contraction; Myocardium; N-Methylscopolamine; Pirenzepine; Quaternary Ammonium Compounds; Receptors, Muscarinic; Scopolamine Derivatives | 1984 |
Inhibitory effects of pirenzepine on muscarinic stimulation of rat pancreas.
Topics: alpha-Amylases; Animals; Atropine; Benzodiazepinones; Calcium; Carbachol; Male; Muscarine; Pancreas; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1983 |
Subclasses of muscarinic receptors in isolated gastric mucosal cells: receptor characterization and parietal cell function.
Topics: Animals; Atropine; Benzodiazepinones; Binding, Competitive; Carbachol; Dogs; Gastric Mucosa; Guanine Nucleotides; Guinea Pigs; In Vitro Techniques; Male; Models, Biological; N-Methylscopolamine; Pilocarpine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1983 |
The binding properties of the muscarinic receptors of the cynomolgus monkey ciliary body and the response to the induction of agonist subsensitivity.
Topics: Animals; Benzodiazepinones; Carbachol; Ciliary Body; Guanylyl Imidodiphosphate; Kinetics; Macaca fascicularis; N-Methylscopolamine; Pilocarpine; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives | 1982 |
Muscarinic receptors in the stomach.
Topics: Animals; Benzodiazepinones; Carbachol; Dogs; Gastric Fundus; Gastric Mucosa; Guanosine Triphosphate; Muscarinic Antagonists; Muscle, Smooth; N-Methylscopolamine; Piperazines; Pirenzepine; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives; Sympathetic Nervous System | 1980 |
M2-type muscarinic receptors mediate prejunctional inhibition of norepinephrine release in the human iris-ciliary body.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Carbachol; Child; Ciliary Body; Diamines; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Iris; Middle Aged; Muscarine; Norepinephrine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1994 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
Pharmacological evidence for the existence of different subtypes of muscarinic acetylcholine receptors for phosphoinositide hydrolysis in neonatal versus adult rat atria.
Topics: Animals; Animals, Newborn; Carbachol; Depression, Chemical; Enzyme Inhibitors; Heart; Heart Atria; Hydrolysis; Muscarinic Agonists; Muscarinic Antagonists; Myocardial Contraction; Myocardium; Phosphatidylinositols; Pirenzepine; Rats; Receptors, Muscarinic; Type C Phospholipases | 1995 |
Regional alterations in M1 muscarinic receptor-G protein coupling in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Binding Sites; Brain; Carbachol; Frontal Lobe; GTP-Binding Proteins; Humans; Pirenzepine; Receptors, Muscarinic; Visual Cortex | 1995 |
Expression of muscarinic M3-receptors coupled to inositol phospholipid hydrolysis in human detrusor cultured smooth muscle cells.
Topics: Carbachol; Cells, Cultured; Diamines; Humans; Hydrolysis; Inositol Phosphates; Methacholine Chloride; Muscarinic Agonists; Muscle, Smooth; Oxotremorine; Phosphatidylinositols; Pilocarpine; Pirenzepine; Receptors, Muscarinic; Urinary Bladder | 1995 |
Cholinergic responsiveness of neurons in the ventroposterior thalamus of the anesthetized rat.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Anesthesia, General; Animals; Carbachol; Electric Stimulation; Evoked Potentials; Glutamates; Glutamic Acid; Hypothalamus, Posterior; Iontophoresis; Male; Neurons; Parasympatholytics; Pirenzepine; Rats; Stereotaxic Techniques | 1993 |
Galanin stimulates striatal acetylcholine release via a mechanism unrelated to cholinergic receptor stimulation.
Topics: Acetylcholine; Animals; Bupivacaine; Carbachol; Chromatography, High Pressure Liquid; Corpus Striatum; Galanin; Injections, Intraperitoneal; Male; Neuropeptides; Oxotremorine; Peptides; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Scopolamine; Substance P | 1993 |
Effects of the muscarinic receptor agonist carbachol and/or antagonist pirenzepine on gastric mucus secretion in rats.
Topics: Animals; Carbachol; Gastric Mucins; Gastric Mucosa; Hydrogen-Ion Concentration; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1993 |
Functional characterization of a muscarinic receptor stimulating gastrin release from rabbit antral G-cells in primary culture.
Topics: Animals; Arecoline; Atropine; Benzodiazepinones; Carbachol; Cell Adhesion; Cell Separation; Cells, Cultured; Gastrins; Immunohistochemistry; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pyloric Antrum; Rabbits; Receptors, Muscarinic | 1994 |
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mulatta; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Quinuclidines | 1994 |
Muscarinic receptor stimulation increases the spontaneous [3H]GABA release in the rat substantia nigra through muscarinic receptors localized on striatonigral terminals.
Topics: Acetylcholine; Animals; Autoradiography; Benzazepines; Calcium; Carbachol; Dendrites; Dopamine; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Male; Muscarinic Agonists; Neostriatum; Nerve Endings; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Substantia Nigra | 1994 |
Formation of inositol phosphates mediated by M3 muscarinic receptors in type-1 and type-2 astrocytes from neonatal rat cerebral cortex.
Topics: Animals; Animals, Newborn; Astrocytes; Atropine; Carbachol; Cells, Cultured; Cerebral Cortex; Inositol Phosphates; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Tubocurarine | 1994 |
Neurotransmitter and neuropeptide modulation of high affinity choline uptake in Limulus brain.
Topics: Animals; Atropine; Brain; Carbachol; Choline; FMRFamide; Horseshoe Crabs; Neuropeptides; Neurotransmitter Agents; Octopamine; Oligopeptides; Oxotremorine; Pirenzepine; Potassium; Serotonin; Tubocurarine | 1995 |
[Inhibitory effect of haloperidol on evoked dopamine release from striatal slices of the rat].
Topics: Acetylcholine; Animals; Carbachol; Corpus Striatum; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Haloperidol; In Vitro Techniques; Pirenzepine; Rats; Rats, Wistar; Stimulation, Chemical | 1995 |
Attenuation of muscarinic receptor-G-protein interaction in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Carbachol; Cerebral Cortex; Choline O-Acetyltransferase; Female; Frontal Lobe; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Male; Middle Aged; Oxotremorine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Pirenzepine; Receptors, Muscarinic; Reference Values; Regression Analysis; Synaptic Membranes; Synaptosomes | 1995 |
Muscarinic inhibition of cardiac norepinephrine and neuropeptide Y release during ischemia and reperfusion.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Neuropeptide Y; Norepinephrine; Oxotremorine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic | 1994 |
Nicotinic cholinergic receptors associated with mammalian cerebral vessels.
Topics: Acetylcholine; Animals; Carbachol; Cerebrovascular Circulation; Humans; In Vitro Techniques; Ligands; Muscle, Smooth, Vascular; Nicotine; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Nicotinic; Swine | 1994 |
Muscarinic (M1) mediation of carbachol-induced theta in the cat entorhinal cortex in vitro.
Topics: Animals; Atropine; Carbachol; Cats; Entorhinal Cortex; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Receptors, Muscarinic; Theta Rhythm | 1994 |
Accumulation of 3H-phosphoinositides mediated by muscarinic receptors in the developing chick retina: inhibition of carbachol-induced response by glutamate receptors.
Topics: Animals; Atropine; Carbachol; Chick Embryo; Glutamic Acid; In Vitro Techniques; N-Methylaspartate; Phosphatidylinositols; Physostigmine; Pirenzepine; Receptors, Glutamate; Receptors, Muscarinic; Retina | 1995 |
Muscarinic M3 receptor-mediated release of gastrin from canine antral G cells in primary culture.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Enterochromaffin Cells; Gastrins; Muscarinic Antagonists; Parasympathetic Nervous System; Parasympatholytics; Piperidines; Pirenzepine; Pyloric Antrum; Receptor, Muscarinic M3; Receptors, Muscarinic; Stimulation, Chemical | 1995 |
Duodenal bicarbonate secretion and mucosal protection. Neurohumoral influence and transport mechanisms.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Animals; Antiporters; Bicarbonates; Biological Transport; Carbachol; Carrier Proteins; Catechol O-Methyltransferase Inhibitors; Catechols; Chloride-Bicarbonate Antiporters; Cyclic AMP; Cytophotometry; Diazepam; Dopamine; Dopamine Agents; Duodenum; Ergolines; Flumazenil; Gastric Mucosa; Intestinal Mucosa; Male; Microvilli; Pentanones; Phentolamine; Pirenzepine; Quinpirole; Radioimmunoassay; Rana catesbeiana; Rats; Rats, Sprague-Dawley; Sodium-Bicarbonate Symporters; Sodium-Hydrogen Exchangers; Ulcer | 1993 |
Nicotinic and muscarinic acetylcholine responses in differentiated PC12 cells.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cell Differentiation; Cell Membrane Permeability; Egtazic Acid; Hexamethonium; Hexamethonium Compounds; Membrane Potentials; Muscarine; Nerve Growth Factors; Nicotine; Nystatin; Parasympatholytics; PC12 Cells; Pirenzepine; Potassium; Receptors, Muscarinic; Receptors, Nicotinic; Tubocurarine | 1994 |
A physiologically-evoked M1-muscarinic depolarization in guinea-pig inferior mesenteric ganglion neurons.
Topics: Action Potentials; Animals; Atropine; Carbachol; Colon; Female; Ganglia, Sympathetic; Gastrointestinal Motility; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Male; Mechanoreceptors; Pirenzepine; Receptors, Muscarinic; Stress, Mechanical | 1994 |
Rat oligodendrocytes express muscarinic receptors coupled to phosphoinositide hydrolysis and adenylyl cyclase.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Diamines; Hydrolysis; Isoproterenol; Nerve Tissue Proteins; Oligodendroglia; Phosphatidylinositols; Pirenzepine; Polymerase Chain Reaction; Rats; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate | 1994 |
Muscarinic receptor-dependent activation of phospholipase C in the developing human fetal central nervous system.
Topics: Atropine; Brain; Carbachol; Cytidine Diphosphate Diglycerides; Embryonic and Fetal Development; Enzyme Activation; Female; Fetus; Humans; In Vitro Techniques; Inositol Phosphates; Pirenzepine; Pregnancy; Pregnancy Trimester, Second; Receptors, Muscarinic; Second Messenger Systems; Type C Phospholipases | 1994 |
Roles of endogenous cholinergic neurons in the induction of long-term potentiation at hippocampal mossy fiber synapses.
Topics: Animals; Aziridines; Carbachol; Choline; Choline O-Acetyltransferase; Cholinergic Agents; Guinea Pigs; Hippocampus; Long-Term Potentiation; Male; Nerve Fibers; Neuromuscular Blocking Agents; Neurons; Parasympathetic Nervous System; Pirenzepine; Synapses | 1994 |
Variation in the affinity of amitriptyline for muscarine receptor subtypes.
Topics: Amitriptyline; Animals; Binding, Competitive; Carbachol; Cerebral Cortex; Female; Guinea Pigs; Heart Atria; Hydrolysis; Male; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Rats; Rats, Wistar; Receptors, Muscarinic; Sympathetic Nervous System; Vas Deferens | 1994 |
Activity-dependent expression and distribution of M1 muscarinic ACh receptors in visual cortex neuronal cultures.
Topics: Animals; Binding Sites; Boron Compounds; Carbachol; Cell Membrane; Cells, Cultured; Microscopy, Phase-Contrast; Muscarinic Antagonists; Neurons; Pirenzepine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tissue Distribution; Visual Cortex | 1994 |
Cholinergic dilatation and constriction of feline cerebral blood vessels are mediated by stimulation of phosphoinositide metabolism via two different muscarinic receptor subtypes.
Topics: Animals; Carbachol; Cats; Cerebral Arteries; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Inositol Phosphates; Muscarinic Antagonists; Muscle, Smooth, Vascular; Parasympatholytics; Phosphatidylinositols; Pia Mater; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasoconstriction; Vasodilation | 1994 |
In vitro pharmacologic characterization of a cholinergic receptor on outer hair cells.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Azocines; Bungarotoxins; Carbachol; Choline; Cholinergic Antagonists; Curare; Dimethylphenylpiperazinium Iodide; Guinea Pigs; Hair Cells, Auditory, Outer; In Vitro Techniques; Membrane Potentials; Nicotine; Piperidines; Pirenzepine; Quinolizines; Receptors, Cholinergic; Strychnine; Trimethaphan | 1994 |
Inhibition of muscarinic receptor-stimulated phosphoinositide metabolism by cocaine, norcocaine and cocaethylene in rat brain.
Topics: Animals; Brain Chemistry; Carbachol; Cerebral Cortex; Cocaine; Female; Male; Muscarinic Antagonists; Neurotransmitter Uptake Inhibitors; Parasympatholytics; Phosphatidylinositols; Pirenzepine; Rats; Rats, Sprague-Dawley | 1994 |
Release of bombesin-like immunoreactivity from synaptosomal membranes isolated from the rat ileum.
Topics: Animals; Atropine; Bombesin; Calcium; Carbachol; Cell Fractionation; Centrifugation, Density Gradient; Ileum; Male; Microscopy, Electron; Pirenzepine; Potassium Chloride; Radioimmunoassay; Rats; Rats, Wistar; Synaptosomes | 1994 |
Characterization of the antinociception produced by intrathecally administered muscarinic agonists in rats.
Topics: Adrenergic alpha-Antagonists; Analgesia; Animals; Carbachol; Diamines; Dioxolanes; Dose-Response Relationship, Drug; Drug Interactions; Injections, Spinal; Male; Mecamylamine; Muscarine; Narcotic Antagonists; Nociceptors; Pain Measurement; Parasympathomimetics; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Receptors, Serotonin; Spinal Cord; Time Factors; Tissue Distribution | 1993 |
Role of intercellular and intracellular communication by nitric oxide in coupling of muscarinic receptors to activation of guanylate cyclase in neuronal cells.
Topics: Alkylation; Animals; Carbachol; Cell Communication; Cyclic GMP; Enzyme Activation; Guanylate Cyclase; Hemoglobins; Mice; Neuroblastoma; Neurons; Nitric Oxide; Pirenzepine; Protein Kinase C; Receptors, Muscarinic; Superoxide Dismutase; Tumor Cells, Cultured | 1993 |
Bidirectional modulation of long-term potentiation by carbachol via M1 and M2 muscarinic receptors in guinea pig hippocampal mossy fiber-CA3 synapses.
Topics: 2-Amino-5-phosphonovalerate; Animals; Carbachol; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Infusions, Parenteral; Male; Nerve Fibers; Neurons; Parasympatholytics; Pirenzepine; Pyramidal Tracts; Receptors, Muscarinic; Synapses | 1993 |
M3 muscarinic receptors on rat colonocytes are coupled to particulate guanylate cyclase activation.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Colon; Enzyme Activation; Guanylate Cyclase; Male; Muscarinic Antagonists; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 1993 |
Effect of M1- and M2-muscarinic drugs on striatal dopamine release and metabolism: an in vivo microdialysis study comparing normal and 6-hydroxydopamine-lesioned rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Atropine; Carbachol; Corpus Striatum; Diamines; Dopamine; Homovanillic Acid; Male; Microdialysis; Oxidopamine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reference Values | 1993 |
M1 muscarinic receptors increase calcium current and phosphoinositide turnover in guinea-pig ventricular cardiocytes.
Topics: Animals; Calcium; Carbachol; Cyclic AMP; Female; Guinea Pigs; Heart Ventricles; In Vitro Techniques; Isoproterenol; Male; Myocardial Contraction; Myocardium; Pertussis Toxin; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; RNA, Messenger; Virulence Factors, Bordetella | 1993 |
Selective blockade of different brain stem muscarinic receptor subtypes: effects on the sleep-wake cycle.
Topics: Animals; Brain Stem; Carbachol; Diamines; Electroencephalography; Male; Microinjections; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Polysomnography; Rats; Reticular Formation; Sleep; Wakefulness | 1994 |
Presynaptic muscarinic receptors modulate acetylcholine release from rat antral mucosal/submucosal nerves.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cholinergic Fibers; Dose-Response Relationship, Drug; Electric Stimulation; Gastric Mucosa; In Vitro Techniques; Male; Pirenzepine; Pyloric Antrum; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Presynaptic | 1994 |
M3 muscarinic receptors mediate an increase in both inositol trisphosphate production and cyclic AMP formation in dog iris sphincter smooth muscle.
Topics: Adenylyl Cyclases; Animals; Calcium; Calcium Channel Blockers; Carbachol; Cyclic AMP; Dogs; Inositol 1,4,5-Trisphosphate; Iris; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pirenzepine; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases | 1994 |
Characterization of muscarinic receptors on guinea pig gallbladder smooth muscle.
Topics: Animals; Autoradiography; Carbachol; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Tetrodotoxin | 1993 |
Secretagogue-induced RVD in HSY cells is due to K+ channels activated by Ca2+ and protein kinase C.
Topics: Atropine; Barium; Calcium; Carbachol; Cell Line; Chloride Channels; Egtazic Acid; Humans; Ionomycin; Kinetics; Pirenzepine; Potassium; Potassium Channel Blockers; Potassium Channels; Protein Kinase C; Quinidine; Salivary Glands; Scorpion Venoms; Tetradecanoylphorbol Acetate; Valinomycin | 1993 |
Agonist-induced down-regulation and antagonist-induced up-regulation of m2- and m3-muscarinic acetylcholine receptor mRNA and protein in cultured cerebellar granule cells.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Cerebellum; Down-Regulation; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; RNA, Messenger; Up-Regulation | 1993 |
Diminished muscarinic receptor-stimulated [3H]-PIP2 hydrolysis in Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Binding, Competitive; Carbachol; Cell Membrane; Choline O-Acetyltransferase; Frontal Lobe; Humans; Hydrolysis; Inositol Phosphates; Kinetics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Diacylglycerol-Lyase; Phosphatidylinositol Phosphates; Phosphoric Diester Hydrolases; Pirenzepine; Receptors, Muscarinic; Reference Values; Synaptic Membranes; Type C Phospholipases | 1993 |
Selective masking of M1-receptors in calf retina membranes by the venom of the marine snail Conus tessulatus.
Topics: Animals; Binding Sites; Binding, Competitive; Carbachol; Cattle; Membranes; Peptide Hydrolases; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Retina; Snails; Venoms | 1993 |
Stimulation of phosphoinositide hydrolysis by muscarinic receptor activation in the rat olfactory bulb.
Topics: Adenylyl Cyclases; Animals; Atropine; Bucladesine; Carbachol; Drug Interactions; Guanosine 5'-O-(3-Thiotriphosphate); Inositol 1,4,5-Trisphosphate; Olfactory Bulb; Phosphatidylinositols; Pirenzepine; Rats; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate | 1993 |
Studies of muscarinic receptor reserve linked to phosphoinositide hydrolysis in parotid gland and cerebral cortex.
Topics: Animals; Carbachol; Cerebral Cortex; Choline; Guinea Pigs; Hydrolysis; In Vitro Techniques; Kinetics; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Parotid Gland; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1993 |
Carbachol-induced phosphoinositide metabolism in slices of rat substantia nigra pars reticulata.
Topics: Animals; Carbachol; Hydrolysis; In Vitro Techniques; Male; Micromanipulation; N-Methylaspartate; Phosphatidylinositols; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Substantia Nigra | 1993 |
Muscarinic M3 receptors mediate total inositol phosphates accumulation in murine HSDM1C1 fibrosarcoma cells.
Topics: Animals; Binding, Competitive; Carbachol; Dioxolanes; Fibrosarcoma; Inositol Phosphates; Mice; Muscarine; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured | 1993 |
Differences between rat dorsal and ventral hippocampus in muscarinic receptor agonist binding and interaction with phospholipase C.
Topics: Alkaloids; Animals; Carbachol; Furans; Guanylyl Imidodiphosphate; Hippocampus; Male; Membranes; Mitochondria; N-Methylscopolamine; Naphthalenes; Oxotremorine; Parasympatholytics; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes; Type C Phospholipases | 1993 |
Differential effects of alkylating agents on the multiple muscarinic receptor subtypes linked to activation of phospholipase C by carbachol in rat brain cortical membranes.
Topics: Alkylating Agents; Animals; Carbachol; Cerebral Cortex; Enzyme Activation; In Vitro Techniques; Male; Mustard Compounds; Piperidines; Pirenzepine; Propylbenzilylcholine Mustard; Quinolines; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Type C Phospholipases | 1993 |
Muscarinic receptor regulation and 2nd messenger responses in rat neocortex cultures.
Topics: Animals; Binding, Competitive; Carbachol; Cells, Cultured; Cerebral Cortex; Down-Regulation; Oxotremorine; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Second Messenger Systems | 1993 |
Muscarinic M1 receptor agonist actions of muscarinic receptor agonists in rabbit vas deferens.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Hippocampus; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Parasympathomimetics; Pirenzepine; Rabbits; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Nicotinic; Vas Deferens | 1993 |
Muscarinic cholinoceptive reticular mechanisms and parabrachial neuron discharge: a novel experimental approach.
Topics: Animals; Brain Stem; Carbachol; Cats; Male; Microinjections; Neostigmine; Neurons; Parasympatholytics; Pirenzepine; Pons; Receptors, Muscarinic; Reticular Formation; Sleep, REM | 1993 |
Subtype of muscarinic receptors mediating relaxation and contraction in the rat iris dilator smooth muscle.
Topics: Alkaloids; Animals; Atropine; Carbachol; Furans; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1993 |
Muscarinic receptors modulate the afterhyperpolarizing potential in neostriatal neurons.
Topics: Action Potentials; Animals; Carbachol; Female; Male; Neostriatum; Pirenzepine; Protein Kinase C; Rats; Rats, Wistar; Receptors, Muscarinic; Time Factors | 1995 |
5-HT1A, GABAB, and pirenzepine-insensitive muscarinic receptors are functionally coupled to distinct pools of the same kind of G proteins in rat hippocampus.
Topics: Animals; Carbachol; Dopamine; GTP-Binding Proteins; Hippocampus; Male; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, GABA-B; Receptors, Serotonin | 1995 |
Constitutive activity of the M1-M4 subtypes of muscarinic receptors in transfected CHO cells and of muscarinic receptors in the heart cells revealed by negative antagonists.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; CHO Cells; Cricetinae; Cyclic AMP; Humans; Inositol Phosphates; Muscarinic Antagonists; Myocardium; N-Methylscopolamine; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Scopolamine Derivatives; Transfection; Tritium | 1995 |
Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
Topics: Alkaloids; Atropine; Carbachol; Carcinoma; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Furans; Humans; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperidines; Pirenzepine | 1995 |
Endogenous nitric oxide signalling system and the cardiac muscarinic acetylcholine receptor-inotropic response.
Topics: Analysis of Variance; Animals; Atropine; Binding Sites; Carbachol; Cyclic GMP; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Heart Atria; Male; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; Parasympatholytics; Phosphatidylinositols; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Type C Phospholipases | 1995 |
Muscarinic cholinergic receptors in brain and atrial membranes of adult brook trout (Salvelinus fontinalis) measured by radioligand binding techniques.
Topics: Animals; Atropine; Binding, Competitive; Brain Chemistry; Carbachol; Heart Atria; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Trout | 1995 |
In vivo and in vitro effects of muscarinic receptor antagonists on contractions and release of [3H]acetylcholine in the rabbit urinary bladder.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Female; Gallamine Triethiodide; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Tritium; Urinary Bladder | 1995 |
The release and subsequent synthesis of histamine in a transfected subclone of rat basophilic leukemia cells that expresses human muscarinic m1 receptors.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Histamine Release; Humans; Leukemia, Basophilic, Acute; Pirenzepine; Rats; Receptors, Muscarinic | 1995 |
Influences of hypothyroidism on lipid composition and inositol lipid-linked receptors responsiveness and protein kinase C (PKC) activity in the cerebral cortex of Lewis rats.
Topics: Animals; Carbachol; Cerebral Cortex; Cycloleucine; Hypothyroidism; Inositol; Inositol Phosphates; Male; Neurotoxins; Pirenzepine; Protein Kinase C; Rats; Rats, Inbred Lew; Receptors, Metabotropic Glutamate; Receptors, Muscarinic | 1996 |
S-(-)-ET 126: a potent and selective M1 antagonist in vitro and in vivo.
Topics: Acetylcholine; Animals; Atrial Function, Left; Carbachol; Dose-Response Relationship, Drug; Ileum; In Vitro Techniques; Male; Mice; Muscarinic Antagonists; Phenylacetates; Piperidines; Pirenzepine; Rabbits; Rats; Vas Deferens | 1996 |
Binding of the labelled muscarinic toxin 125I-MT1 to rat brain muscarinic M1 receptors.
Topics: Alkaloids; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Elapid Venoms; Furans; Gallamine Triethiodide; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; Naphthalenes; Oxotremorine; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Protein Binding; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Synaptic Membranes; Tubocurarine | 1996 |
Carbachol stimulates inositol phosphate formation in rat thalamus slices through muscarinic M3-receptor activation.
Topics: Animals; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Inositol Phosphates; Male; Muscarinic Agonists; Muscarinic Antagonists; Organ Culture Techniques; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Thalamus; Tritium | 1996 |
Functional partial agonism at cloned human muscarinic acetylcholine receptors.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Atropine; Binding, Competitive; Carbachol; Cells, Cultured; Cloning, Molecular; Dose-Response Relationship, Drug; GTP-Binding Proteins; Humans; Muscarinic Agonists; Muscarinic Antagonists; Nicotinic Agonists; Pirenzepine; Receptors, Muscarinic | 1996 |
Muscarinic receptor subtypes in the submandibular gland and the urinary bladder of the rabbit: in vivo and in vitro functional comparisons of receptor antagonists.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscarinic Antagonists; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Submandibular Gland; Urinary Bladder | 1995 |
Muscarine receptor activation in the substantia gelatinosa of the spinal trigeminal nucleus of the guinea pig.
Topics: Animals; Carbachol; Cricetinae; Evoked Potentials; In Vitro Techniques; Male; Membrane Potentials; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Patch-Clamp Techniques; Pirenzepine; Receptors, Glutamate; Substantia Gelatinosa; Trigeminal Nucleus, Spinal | 1996 |
Evidence for the presence of regional differences in the subtype specificity of muscarinic receptors in rabbit lower urinary tract.
Topics: Animals; Atropine; Carbachol; Diamines; Female; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Pirenzepine; Rabbits; Receptors, Muscarinic; Species Specificity; Urethra; Urinary Bladder | 1997 |
A muscarinic acetylcholine receptor, present in the epithelial cell line from Chironomus tentans.
Topics: Animals; Atropine; Binding Sites; Binding, Competitive; Blotting, Western; Carbachol; Cell Line; Chironomidae; Ecdysterone; Epithelium; Ethylmaleimide; Guanylyl Imidodiphosphate; Kinetics; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Cholinergic | 1996 |
Circulating antibodies against rat parotid gland M3 muscarinic receptors in primary Sjögren's syndrome.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Animals; Antibodies, Blocking; Atropine; Carbachol; Carbamates; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Parotid Gland; Phenylcarbamates; Phosphatidylinositols; Piperidines; Pirenzepine; Protease Inhibitors; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sjogren's Syndrome | 1996 |
Involvement of M2 receptor in an enhancement of long-term potentiation by carbachol in Schaffer collateral-CA1 synapses of hippocampal slices.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Evoked Potentials; Guinea Pigs; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Receptors, Muscarinic; Synapses | 1997 |
Modulation of the pressor response elicited by carbachol and electrical stimulation of the amygdala by muscarinic antagonists in conscious rats.
Topics: Amygdala; Analysis of Variance; Animals; Blood Pressure; Carbachol; Electric Stimulation; Female; Heart Rate; Injections, Intraventricular; Microinjections; Muscarinic Agonists; Muscarinic Antagonists; Parasympatholytics; Pirenzepine; Rats; Rats, Sprague-Dawley | 1997 |
Cholinergic modulation of electrogenic ion transport in different regions of the rat small intestine.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analysis of Variance; Animals; Atropine; Bethanechol; Carbachol; Chlorides; Diamines; Duodenum; Ileum; Intestinal Mucosa; Ion Transport; Jejunum; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Structure-Activity Relationship; Tetrodotoxin | 1997 |
Exocytotic release from neuronal cell bodies, dendrites and nerve terminals in sympathetic ganglia of the rat, and its differential regulation.
Topics: Animals; Atropine; Carbachol; Cell Membrane; Dendrites; Exocytosis; Ganglia, Sympathetic; Male; Membrane Potentials; Nerve Endings; Neurons; Nicotine; Oxotremorine; Parasympatholytics; Pirenzepine; Potassium; Rats; Rats, Wistar; Receptors, Muscarinic; Regression Analysis; Synapses | 1997 |
M3 muscarinic receptor-mediated enhancement of NMDA-evoked adenosine release in rat cortical slices in vitro.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Drug Synergism; In Vitro Techniques; Kinetics; Magnesium; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylaspartate; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic | 1997 |
Carbachol-induced pressor responses and muscarinic M1 receptors in the central nucleus of amygdala in conscious rats.
Topics: Amygdala; Animals; Blood Pressure; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intraventricular; Male; Muscarinic Agonists; Muscarinic Antagonists; Parasympatholytics; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 1997 |
Enhancement of maximal activation of neuronal nitric oxide synthase at muscarinic M1 receptors following prolonged agonist treatment.
Topics: Analysis of Variance; Animals; Carbachol; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Enzyme Activation; Muscarinic Agonists; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pirenzepine; Receptor, Muscarinic M1; Receptors, Muscarinic | 1997 |
Carbachol-induced inositol phosphate formation in rat striatum is mediated by both M1 and M3 muscarinic receptors.
Topics: Animals; Carbachol; Corpus Striatum; Drug Evaluation, Preclinical; In Vitro Techniques; Inositol Phosphates; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar | 1997 |
Properties of carbachol-induced oscillatory activity in rat hippocampus.
Topics: 2-Amino-5-phosphonovalerate; Animals; Atropine; Bicuculline; Carbachol; Dicyclomine; Evoked Potentials; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA Antagonists; GABA-B Receptor Antagonists; Hippocampus; In Vitro Techniques; Kinetics; Male; Microelectrodes; Neurons; Nicotine; Oscillometry; Phosphinic Acids; Pirenzepine; Potassium; Propanolamines; Pyramidal Cells; Quinoxalines; Rats; Rats, Sprague-Dawley; Reaction Time; Receptors, AMPA; Receptors, GABA-B | 1997 |
[Gamma-35S]GTP autoradiography allows region-specific detection of muscarinic receptor-dependent G-protein activation in the chick optic tectum.
Topics: Animals; Animals, Newborn; Autoradiography; Carbachol; Chickens; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Male; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Receptors, Muscarinic; Sulfur Radioisotopes; Superior Colliculi; Time Factors; Tissue Distribution | 1997 |
Two opposite signal transducing mechanisms regulate a G-protein-coupled guanylyl cyclase.
Topics: Animals; Carbachol; Cattle; Cell Membrane; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanylate Cyclase; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Signal Transduction; Trachea; Virulence Factors, Bordetella | 1998 |
Muscarinic facilitation of GABA release in substantia gelatinosa of the rat spinal dorsal horn.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Diamines; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Muscarinic Agonists; Neostigmine; Neurons; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin | 1998 |
Characterization of muscarinic receptors mediating the contraction of the urinary detrusor muscle in cynomolgus monkeys and guinea pigs.
Topics: Animals; Carbachol; Diamines; Female; Guinea Pigs; Macaca fascicularis; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Urinary Bladder | 1998 |
M2 and M3 muscarinic receptors couple, respectively, with activation of nonselective cationic channels and potassium channels in intestinal smooth muscle cells.
Topics: Animals; Atropine; Calcium; Carbachol; Guinea Pigs; Male; Muscarinic Agonists; Muscle, Smooth; Piperidines; Pirenzepine; Potassium Channels; Receptors, Muscarinic | 1998 |
Telenzepine-sensitive muscarinic receptors on rat pancreatic acinar cells.
Topics: Animals; Blotting, Southern; Carbachol; Cholinergic Antagonists; Dose-Response Relationship, Drug; Enzyme Precursors; In Vitro Techniques; Male; Pancreas; Parasympatholytics; Pirenzepine; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Time Factors | 1998 |
Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Behavior, Animal; Carbachol; Cataplexy; Cholinergic Fibers; Dogs; Feeding Behavior; Female; GABA Agonists; Gallamine Triethiodide; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Muscimol; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Piperidines; Pirenzepine; Prosencephalon | 1998 |
Cholinergic regulation of the rat adrenal zona glomerulosa.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Aldosterone; Animals; Atropine; Carbachol; Choline O-Acetyltransferase; Cholinergic Fibers; Histocytochemistry; Immunohistochemistry; Male; Microscopy, Immunoelectron; Muscarinic Agonists; Muscarinic Antagonists; Organ Culture Techniques; Pirenzepine; Rats; Rats, Sprague-Dawley; Zona Glomerulosa | 1998 |
Role of nitric oxide production through M2-cholinergic receptors in cultured rat ventricular myocytes.
Topics: Animals; Carbachol; Cells, Cultured; Diamines; Guanylate Cyclase; Heart Ventricles; Muscarinic Antagonists; Myocardial Contraction; Nitric Oxide; Nitric Oxide Synthase; omega-N-Methylarginine; Pirenzepine; Quinuclidinyl Benzilate; Rats; Receptor, Muscarinic M2; Receptors, Muscarinic; Signal Transduction | 1998 |
Histamine H2-receptor antagonism of T-593, an anti-ulcer agent: studies on aminopyrine accumulation in isolated canine gastric mucosal cells.
Topics: Aminopyrine; Animals; Anti-Ulcer Agents; Bucladesine; Carbachol; Carbon Radioisotopes; Cholinergic Agonists; Dogs; Dose-Response Relationship, Drug; Famotidine; Gastric Acid; Gastric Mucosa; Guanidines; Histamine; Histamine H2 Antagonists; Omeprazole; Pentagastrin; Pirenzepine; Ranitidine; Sulfones | 1998 |
3-Alpha-chloro-imperialine, a potent blocker of cholinergic presynaptic modulation of glutamatergic afferents in the rat neostriatum.
Topics: 4-Aminopyridine; Afferent Pathways; Animals; Atropine; Bicuculline; Carbachol; Cevanes; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; Gallamine Triethiodide; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neostriatum; Neurons; Pirenzepine; Rats; Rats, Wistar; Receptors, GABA-A; Receptors, Muscarinic; Synapses | 1998 |
Muscarinic activation of a non-selective cationic conductance in pyramidal neurons in rat basolateral amygdala.
Topics: Amygdala; Animals; Barium; Calcium; Carbachol; Cesium; Female; Flunarizine; Gallamine Triethiodide; In Vitro Techniques; Male; Membrane Potentials; Neurons; Pirenzepine; Pyramidal Cells; Rats; Rats, Wistar | 1999 |
Rapid eye movement sleep induction by vasoactive intestinal peptide infused into the oral pontine tegmentum of the rat may involve muscarinic receptors.
Topics: Animals; Atropine; Autoradiography; Brain Chemistry; Carbachol; Dose-Response Relationship, Drug; Male; Microinjections; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Pons; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Sleep, REM; Tritium; Vasoactive Intestinal Peptide | 1999 |
Selective activation of heterologously expressed G protein-gated K+ channels by M2 muscarinic receptors in rat sympathetic neurones.
Topics: Animals; Barium; Benzodiazepines; Biolistics; Calcium Channels; Carbachol; Cells, Cultured; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Green Fluorescent Proteins; GTP-Binding Proteins; Luminescent Proteins; Male; Membrane Potentials; Neurons; Patch-Clamp Techniques; Pirenzepine; Potassium Channels; Potassium Channels, Inwardly Rectifying; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Recombinant Proteins; Superior Cervical Ganglion; Transfection | 1999 |
Activation of muscarinic M3-like receptors and beta-adrenoceptors, but not M2-like muscarinic receptors or alpha-adrenoceptors, directly modulates corticostriatal neurotransmission in vitro.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic Fibers; Animals; Carbachol; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Imidazoles; Isoproterenol; Male; Medetomidine; Mice; Mice, Inbred DBA; Muscarinic Agonists; Muscarinic Antagonists; Phenylephrine; Piperidines; Pirenzepine; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Muscarinic; Scopolamine; Synaptic Transmission | 1999 |
Enhancement of GABA-activated current by muscarine in rat dorsal root ganglion neurons.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Carbachol; Carbolines; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Female; GABA Agonists; GABA Modulators; Gallamine Triethiodide; gamma-Aminobutyric Acid; Ganglia, Spinal; Ion Channel Gating; Ion Channels; Male; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nerve Tissue Proteins; Nicotinic Antagonists; Patch-Clamp Techniques; Pentobarbital; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Muscarinic | 1999 |
Pharmacological analysis of the novel mode of interaction between xanomeline and the M1 muscarinic acetylcholine receptor.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; CHO Cells; Citrulline; Cricetinae; Humans; Kinetics; Muscarinic Agonists; N-Methylscopolamine; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Pirenzepine; Pyridines; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Recombinant Proteins; Thiadiazoles; Transfection; Tritium | 1999 |
Presynaptic muscarinic (M3) receptors reduce excitatory transmission in dopamine neurons of the rat mesencephalon.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Atropine; Carbachol; Diamines; Dicyclomine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptor, Muscarinic M3; Receptors, Muscarinic; Synaptic Transmission; Tetrodotoxin | 1999 |
Reduced high-affinity agonist binding at the M(1) muscarinic receptor in Alzheimer's disease brain: differential sensitivity to agonists and divalent cations.
Topics: Acetylcholine; Aged; Alzheimer Disease; Brain; Carbachol; Cations, Divalent; Chlorides; Edetic Acid; Female; Guanylyl Imidodiphosphate; Humans; Kinetics; Magnesium Chloride; Male; Manganese Compounds; Muscarinic Agonists; Oxotremorine; Pirenzepine; Receptor, Muscarinic M1; Receptors, Muscarinic; Reference Values | 1999 |
Microinjections of carbachol into the phrenic motor nucleus inhibit phrenic nerve activity in the rat.
Topics: Animals; Carbachol; Diamines; Male; Microinjections; Parasympatholytics; Phrenic Nerve; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic; Spinal Cord | 1999 |
Effect of cholinergic drugs on the concentration of intracellular free calcium of rat pituitary intermediate lobe cells.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Age Factors; Animals; Atropine; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Cytosol; Female; Male; Melanocytes; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Piperidines; Pirenzepine; Pituitary Gland; Rats; Rats, Wistar; Vasodilator Agents | 1999 |
Muscarinic control of intracortical connections to layer II in rat entorhinal cortex slice.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Entorhinal Cortex; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic; Synaptic Transmission | 1999 |
The assessment of antagonist potency under conditions of transient response kinetics.
Topics: Animals; Artifacts; Atropine; Binding, Competitive; Calcium; Carbachol; CHO Cells; Cricetinae; Drug Antagonism; Humans; Intracellular Fluid; Kinetics; Models, Biological; Monte Carlo Method; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Pyridines; Radioligand Assay; Receptor, Muscarinic M1; Receptors, Muscarinic; Thiadiazoles; Time Factors | 1999 |
Muscarinic receptor heterogeneity in follicle-enclosed Xenopus oocytes.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Gene Expression; Membrane Potentials; Muscarinic Antagonists; Oocytes; Ovarian Follicle; Oxotremorine; Patch-Clamp Techniques; Piperidines; Pirenzepine; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Tropicamide; Xenopus laevis | 1999 |
Isolation of a muscarinic alkaloid with ocular hypotensive action from Trophis racemosa.
Topics: Acetylcholine; Alkaloids; Animals; Antihypertensive Agents; Atropine; Carbachol; Dogs; Female; Gallamine Triethiodide; Guinea Pigs; Hexamethonium; Ileum; Intraocular Pressure; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Ocular Hypotension; Pentolinium Tartrate; Pilocarpine; Pirenzepine; Plant Extracts; Plants, Medicinal; Trachea | 1999 |
Muscarinic-induced modulation of potassium conductances is unchanged in mouse hippocampal pyramidal cells that lack functional M1 receptors.
Topics: Action Potentials; Animals; Atropine; Carbachol; Elapid Venoms; Hippocampus; Ion Channel Gating; Ion Transport; Mice; Mice, Knockout; Muscarinic Agonists; Muscarinic Antagonists; Patch-Clamp Techniques; Pirenzepine; Potassium; Potassium Channels; Pyramidal Cells; Receptor, Muscarinic M1; Receptors, Muscarinic | 2000 |
M(2) and M(4) receptor knockout mice: muscarinic receptor function in cardiac and smooth muscle in vitro.
Topics: Adenosine; Animals; Carbachol; Heart Rate; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic | 2000 |
Carbachol and acetylcholine delay the early postdenervation depolarization of muscle fibres through M1-cholinergic receptors.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Carbachol; Culture Techniques; Diaphragm; Male; Membrane Potentials; Muscarinic Agonists; Muscarinic Antagonists; Muscle Denervation; Muscle Fibers, Skeletal; Oxotremorine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic | 2000 |
Influence of gender and the oestrous cycle on in vitro contractile responses of the rat urinary bladder to cholinergic stimulation.
Topics: Animals; Carbachol; Cholinergic Agonists; Diamines; Electric Stimulation; Estrus; Female; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Sex Characteristics; Time Factors; Urinary Bladder; Uterine Contraction | 2000 |
Functional characterization of rat submaxillary gland muscarinic receptors using microphysiometry.
Topics: Alkaloids; Animals; Atropine; Benzhydryl Compounds; Benzodiazepinones; Binding, Competitive; Biosensing Techniques; Carbachol; Cholinergic Agonists; Cresols; Diamines; Dose-Response Relationship, Drug; Furans; Male; Mandelic Acids; Muscarinic Antagonists; Naphthalenes; Phenethylamines; Phenylpropanolamine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Tolterodine Tartrate | 2001 |
The allosteric interaction of otenzepad (AF-DX 116) at muscarinic M2 receptors in guinea pig atria.
Topics: Acetylcholine; Allosteric Regulation; Animals; Atropine; Carbachol; Cardiotonic Agents; Dexetimide; Electric Stimulation; Female; Gallamine Triethiodide; Guinea Pigs; Heart Atria; In Vitro Techniques; Kinetics; Male; Muscarinic Antagonists; N-Methylscopolamine; Nicotinic Antagonists; Parasympatholytics; Phthalimides; Pirenzepine; Quaternary Ammonium Compounds; Radioligand Assay; Receptor, Muscarinic M2; Receptors, Muscarinic | 2001 |
Agonist activation of cytosolic Ca2+ in subfornical organ cells projecting to the supraoptic nucleus.
Topics: Acetylcholine; Angiotensin II; Animals; Axonal Transport; Calcium; Carbachol; Cytosol; Female; Fluorescent Dyes; Fura-2; In Vitro Techniques; Kinetics; Neural Pathways; Neurons; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptors, Muscarinic; Subfornical Organ; Supraoptic Nucleus | 2001 |
Effects of cholinergic agents on the vasopressin-mediated water transport in the isolated toad bladder.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arginine Vasopressin; Atropine; Biological Transport; Bufo marinus; Calcium; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; In Vitro Techniques; Isotonic Solutions; Lanthanum; Osmolar Concentration; Piperidines; Pirenzepine; Urinary Bladder; Vasoconstrictor Agents; Water | 2001 |
Muscarinic activation of inwardly rectifying K(+) conductance reduces EPSPs in rat hippocampal CA1 pyramidal cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Cholinergic Agents; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Gallamine Triethiodide; Glutamic Acid; Hippocampus; Muscarinic Antagonists; Nicotinic Antagonists; Organ Culture Techniques; Parasympatholytics; Patch-Clamp Techniques; Pirenzepine; Potassium Channels, Inwardly Rectifying; Pyramidal Cells; Rats; Rats, Wistar; Receptor, Muscarinic M2; Receptors, Muscarinic; Stimulation, Chemical | 2001 |
Muscarinic receptors control K+ secretion in inner ear strial marginal cells.
Topics: Adrenergic beta-Agonists; Animals; Atropine; Calcium; Carbachol; Cholinergic Agonists; Cloning, Molecular; Cyclic AMP; Diamines; Dose-Response Relationship, Drug; Gerbillinae; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stria Vascularis | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pirenzepine; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Purinergic; Theophylline; Urinary Bladder | 2001 |
Activation of nitric oxide synthase through muscarinic receptors in rat parotid gland.
Topics: Amylases; Animals; Atropine; Binding, Competitive; Carbachol; Cell Membrane; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Parotid Gland; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Specific Pathogen-Free Organisms | 2002 |
Muscarinic receptor knockout mice: role of muscarinic acetylcholine receptors M(2), M(3), and M(4) in carbamylcholine-induced gallbladder contractility.
Topics: Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Cardiovascular Agents; Cholinesterase Inhibitors; Drug Interactions; Gallbladder; Indomethacin; Mice; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Neostigmine; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptors, Muscarinic | 2002 |
[Muscarinic receptors of the neostriatum -- important targets of regulation of instrumental movement and posture].
Topics: Animals; Carbachol; Cholinergic Agonists; Dogs; Microinjections; Movement; Muscarinic Antagonists; Muscle Rigidity; Neostriatum; Pirenzepine; Posture; Receptors, Muscarinic; Scopolamine; Time Factors | 2002 |
PMA decreases the proliferation of retinal cells in vitro: the involvement of acetylcholine and BDNF.
Topics: Acetylcholine; Alkaloids; Amacrine Cells; Animals; Atropine; Benzophenanthridines; Brain-Derived Neurotrophic Factor; Calcium; Carbachol; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Eye Proteins; Growth Inhibitors; Isoenzymes; MAP Kinase Signaling System; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Phenanthridines; Pirenzepine; Protein Kinase C; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Retina; Signal Transduction; Tetradecanoylphorbol Acetate | 2003 |
Cholinergic mechanism in the lateral septal area is involved in the stress-induced blood pressure increase in rats.
Topics: Animals; Blood Pressure; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Epinephrine; GABA Agonists; Injections, Intraventricular; Male; Muscarinic Antagonists; Muscimol; Norepinephrine; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Restraint, Physical; Septal Nuclei; Stress, Physiological | 2003 |
Heterogeneity of presynaptic muscarinic receptors mediating inhibition of sympathetic transmitter release: a study with M2- and M4-receptor-deficient mice.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Diamines; Genetic Heterogeneity; Heart Atria; Male; Mice; Mice, Knockout; Muscarinic Antagonists; Norepinephrine; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Receptors, Presynaptic; Urinary Bladder; Vas Deferens | 2003 |
Scintillation proximity assay of inositol phosphates in cell extracts: high-throughput measurement of G-protein-coupled receptor activation.
Topics: Animals; Atropine; Carbachol; Cell Extracts; Cell Line; CHO Cells; Chromatography, Ion Exchange; Cricetinae; GTP-Binding Proteins; Humans; Inositol; Inositol Phosphates; Lithium Chloride; Muscarinic Antagonists; Pirenzepine; Receptors, Muscarinic; Recombinant Proteins; Scintillation Counting; Silicates; Tritium; Yttrium; Yttrium Radioisotopes | 2003 |
6beta-acetoxy nortropane regulated processing of amyloid precursor protein in CHOm1 cells and rat brain.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Atropine; Carbachol; Cerebral Cortex; CHO Cells; Cricetinae; Hippocampus; Immunoblotting; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Nortropanes; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptors, Muscarinic | 2003 |
Castration decreases amylase release associated with muscarinic acetylcholine receptor downregulation in rat parotid gland.
Topics: Amylases; Animals; Binding, Competitive; Carbachol; Cholinergic Agonists; Down-Regulation; Inositol Phosphates; Male; Orchiectomy; Parotid Gland; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Muscarinic | 2003 |
Does the cholinergic system modulate gastrointestinal slow waves during less active phases of migrating myoelectric complex in healthy rams?
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cholinergic Agents; Electrodes, Implanted; Electromyography; Fasting; Hexamethonium; Intestine, Small; Male; Myoelectric Complex, Migrating; Pirenzepine; Pyloric Antrum; Receptors, Cholinergic; Sheep; Time Factors | 2003 |
Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill.
Topics: Adenylyl Cyclase Inhibitors; Animals; Arecoline; Atropine; Carbachol; Colforsin; Cyclic AMP; Cytoplasmic Granules; Light; Muscarinic Agonists; Muscarinic Antagonists; Perciformes; Pigment Epithelium of Eye; Piperidines; Pirenzepine; Quaternary Ammonium Compounds; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Retinal Pigments; Second Messenger Systems; Tropicamide | 2004 |
Cholinergic regulation of the evoked quantal release at frog neuromuscular junction.
Topics: Acetylcholine; Action Potentials; Animals; Arecoline; Carbachol; Cholinergic Agonists; Diamines; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Neural Conduction; Neuromuscular Junction; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Parasympatholytics; Pirenzepine; Rana ridibunda; Receptors, Muscarinic; Synaptic Transmission; Tubocurarine | 2004 |
Distinct properties of carbachol- and DHPG-induced network oscillations in hippocampal slices.
Topics: Action Potentials; Amino Acids; Animals; Animals, Newborn; Benzodiazepines; Bicuculline; Carbachol; Cholinergic Agonists; Diamines; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; GABA Agonists; GABA Antagonists; Hippocampus; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Muscarinic Antagonists; Pirenzepine; Pyridines; Rats; Receptors, Metabotropic Glutamate; Spectrum Analysis; Substance P; Xanthenes; Zolpidem | 2004 |
Effects of pirenzepine on pupil size and accommodation in rhesus monkeys.
Topics: Accommodation, Ocular; Animals; Carbachol; Conjunctiva; Electrodes, Implanted; Injections; Macaca mulatta; Microelectrodes; Muscarinic Antagonists; Ophthalmic Solutions; Pirenzepine; Pupil; Refraction, Ocular | 2004 |
Spatial memory in aged rats is related to PKCgamma-dependent G-protein coupling of the M1 receptor.
Topics: Age Factors; Aging; Analysis of Variance; Animals; Behavior, Animal; Binding, Competitive; Carbachol; Cell Count; Choice Behavior; Cholinergic Agonists; Dendrites; Dose-Response Relationship, Drug; Hippocampus; Immunohistochemistry; Male; Maze Learning; Memory; Muscarinic Antagonists; Pirenzepine; Protein Kinase C; Radioligand Assay; Rats; Rats, Inbred F344; Receptor, Muscarinic M1; Spatial Behavior; Tritium | 2005 |
Cholinergically stimulated gastric acid secretion is mediated by M(3) and M(5) but not M(1) muscarinic acetylcholine receptors in mice.
Topics: Animals; Carbachol; Cholinergic Agonists; Female; Gastric Acid; Male; Mice; Mice, Knockout; Muscarinic Antagonists; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptor, Muscarinic M5; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stomach | 2005 |
[Participation of the neostriatum transmission system in automation of motor skills in dogs].
Topics: Animals; Carbachol; Cholinergic Agonists; Dogs; Motor Skills; Muscarinic Antagonists; Neostriatum; Pirenzepine | 2004 |
Signal transduction underlying carbachol-induced PGE2 generation and cox-1 mRNA expression of rat brain.
Topics: Animals; Carbachol; Cholinergic Agonists; Cyclic GMP; Cyclooxygenase 1; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Frontal Lobe; Gene Expression Regulation; Male; Membrane Proteins; Models, Biological; Muscarinic Antagonists; Nitric Oxide Synthase; Phosphatidylinositols; Piperidines; Pirenzepine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2005 |
Expression and localization of muscarinic acetylcholine receptor subtypes in rat efferent ductules and epididymis.
Topics: Animals; Atropine; Carbachol; Cell Membrane; Diamines; Ejaculatory Ducts; Epididymis; Immunohistochemistry; In Vitro Techniques; Male; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 2006 |
Excitatory effect of M1 muscarinic acetylcholine receptor on automaticity of mouse heart.
Topics: Action Potentials; Animals; Carbachol; Cholinergic Agonists; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Mice; Muscarinic Antagonists; Pirenzepine; Receptor, Muscarinic M1; Stimulation, Chemical | 2005 |
Muscarinic regulation of neonatal rat bladder spontaneous contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium Channel Agonists; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Diamines; Electric Stimulation; Muscle Contraction; Muscle Hypertonia; Muscle, Smooth; Parasympatholytics; Peptides; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2006 |
M1 muscarinic receptors contribute to, whereas M4 receptors inhibit, dopamine D1 receptor-induced [3H]-cyclic AMP accumulation in rat striatal slices.
Topics: Alkaloids; Animals; Benzazepines; Carbachol; Cholinergic Agonists; Corpus Striatum; Cyclic AMP; Dopamine Agonists; Furans; Male; Muscarinic Antagonists; N-Methylscopolamine; Naphthalenes; Parasympatholytics; Piperidines; Pirenzepine; Protein Kinase C; Radioligand Assay; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Receptors, Dopamine D1 | 2006 |
Agonist and antagonist sensitivity of non-selective cation channel currents evoked by muscarinic receptor stimulation in bovine ciliary muscle cells.
Topics: Animals; Atropine; Barium; Carbachol; Cattle; Cells, Cultured; Ciliary Body; Dose-Response Relationship, Drug; Membrane Potentials; Microscopy, Fluorescence; Muscarinic Agonists; Muscarinic Antagonists; Muscle Cells; Patch-Clamp Techniques; Piperidines; Pirenzepine; Receptor, Muscarinic M3; TRPC Cation Channels | 2006 |
Muscarinic cholinoceptor activation modulates DNA synthesis and CD40 expression in fibroblast cells.
Topics: Atropine; Calmodulin; Carbachol; CD40 Antigens; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Fibroblasts; Flow Cytometry; Humans; Inositol Phosphates; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Pyrrolidinones; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Muscarinic; Trifluoperazine; Type C Phospholipases | 2006 |
Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: studies with muscarinic receptor knockout mice.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gastric Emptying; Gastric Fundus; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Physostigmine; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Stomach | 2007 |
Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction.
Topics: Adult; Aged; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Pyrrolidines; Receptors, Muscarinic; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive | 2007 |
Muscarinic receptor subtypes mediating positive and negative inotropy in the developing chick ventricle.
Topics: Action Potentials; Alkaloids; Animals; Carbachol; Chick Embryo; Dose-Response Relationship, Drug; Furans; Heart Ventricles; Myocardial Contraction; Naphthalenes; Piperidines; Pirenzepine; Receptors, Muscarinic | 2007 |
M1 muscarinic receptor modulation of Kir2 channels enhances temporal summation of excitatory synaptic potentials in prefrontal cortex pyramidal neurons.
Topics: Alkaloids; Animals; Animals, Newborn; Benzophenanthridines; Carbachol; Cells, Cultured; Cholinergic Agonists; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Estrenes; Excitatory Postsynaptic Potentials; Muscarinic Antagonists; Patch-Clamp Techniques; Pirenzepine; Potassium Channels, Inwardly Rectifying; Potassium Chloride; Prefrontal Cortex; Pyramidal Cells; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1 | 2007 |
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection | 2007 |
Changes in muscarinic receptors in the toad urothelial cell line TBM-54 following acrolein treatment.
Topics: Acrolein; Animals; Blotting, Western; Bufo marinus; Carbachol; Cell Line; Diamines; Dose-Response Relationship, Drug; Extracellular Fluid; Hydrogen-Ion Concentration; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptors, Muscarinic; Urinary Bladder; Urothelium | 2008 |
Ligand characterization using microphysiometry.
Topics: Animals; Carbachol; CHO Cells; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Ligands; Microchemistry; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Protons; Receptor, Muscarinic M1; Recombinant Fusion Proteins; Transfection | 2001 |
Muscarinic cholinergic modulation of synaptic transmission and plasticity in rat hippocampus following chronic lead exposure.
Topics: Animals; Carbachol; Diamines; Environmental Pollutants; Excitatory Postsynaptic Potentials; Female; Hippocampus; In Vitro Techniques; Lead; Learning; Long-Term Potentiation; Male; Memory; Muscarinic Agonists; Muscarinic Antagonists; Neuronal Plasticity; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Synaptic Transmission | 2009 |
Presynaptic muscarinic receptors enhance glutamate release at the mitral/tufted to granule cell dendrodendritic synapse in the rat main olfactory bulb.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Age Factors; Animals; Animals, Newborn; Biophysics; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Glutamic Acid; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Membrane Potentials; Models, Biological; Muscarinic Antagonists; Neurons; Olfactory Bulb; Patch-Clamp Techniques; Picrotoxin; Pirenzepine; Presynaptic Terminals; Rats; Receptors, Muscarinic; Sodium Channel Blockers; Tetrodotoxin; Valine | 2009 |
Muscarinic receptor type 1 (M1) stimulation, probably through KCNQ/Kv7 channel closure, increases spontaneous GABA release at the dendrodendritic synapse in the mouse accessory olfactory bulb.
Topics: Alkaloids; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels, R-Type; Carbachol; Carbamates; Cholinergic Agonists; Dendrites; Diclofenac; Excitatory Amino Acid Antagonists; Furans; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; KCNQ Potassium Channels; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Naphthalenes; Nimodipine; Olfactory Bulb; Patch-Clamp Techniques; Phenylenediamines; Piperidines; Pirenzepine; Potassium Channel Blockers; Receptor, Muscarinic M1; Receptors, Glutamate; Synapses | 2010 |
Intracellular distribution of functional M(1) -muscarinic acetylcholine receptors in N1E-115 neuroblastoma cells.
Topics: Animals; Atropine; Blotting, Western; Calcium; Carbachol; Cell Line, Tumor; Elapid Venoms; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Immunohistochemistry; Inositol Phosphates; Kinetics; Mice; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Neuroblastoma; Peptides, Cyclic; Pirenzepine; Protein Kinase Inhibitors; Quinuclidinyl Benzilate; Receptor, Muscarinic M1; Receptors, Cell Surface | 2011 |
Modulating activity of M1 receptor to the reaction of ileal smooth muscle.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Ileum; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1 | 2011 |
Role of M1 receptor in regulation of gastric fundus smooth muscle contraction.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Gastric Fundus; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Statistics as Topic | 2011 |
Muscarinic receptor subtypes involved in regulation of colonic motility in mice: functional studies using muscarinic receptor-deficient mice.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Biomechanical Phenomena; Carbachol; Colon; Defecation; Female; Gastrointestinal Motility; Gene Knockout Techniques; In Vitro Techniques; Male; Mice; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Pirenzepine; Receptors, Muscarinic | 2011 |
Colonic inflammation increases the contribution of muscarinic M2 receptors to carbachol-induced contraction of the rat colon.
Topics: Animals; Carbachol; Colitis; Colon; Diamines; Disease Models, Animal; Inflammation; Isometric Contraction; Male; Muscarinic Agonists; Muscarinic Antagonists; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2 | 2011 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium | 2011 |
Cholinergic impact on neuroplasticity drives muscarinic M1 receptor mediated differentiation into neurons.
Topics: Adult Stem Cells; Animals; Carbachol; Cell Differentiation; Cholinergic Agonists; Epidermal Growth Factor; Fibroblast Growth Factor 2; Hippocampus; Mice; Muscarinic Antagonists; Neural Stem Cells; Neuronal Plasticity; Pirenzepine; Receptor, Muscarinic M1; Synaptic Transmission | 2013 |
Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle.
Topics: Amides; Calcium; Carbachol; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Maleimides; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Protein Kinase C; Pyridines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; rho-Associated Kinases; Signal Transduction; Urinary Bladder | 2012 |
Activation of muscarinic receptors increases the activity of the granule neurones of the rat dorsal cochlear nucleus--a calcium imaging study.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Calcium; Carbachol; Cochlear Nucleus; Female; Male; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Patch-Clamp Techniques; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 2012 |
Muscarinic receptor subtypes involved in urothelium-derived relaxatory effects in the inflamed rat urinary bladder.
Topics: Animals; Carbachol; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Synthase; Nitroarginine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Urinary Bladder; Urothelium | 2012 |
Muscarinic acetylcholine receptor-mediated effects in slices from human epileptogenic cortex.
Topics: Action Potentials; Adult; Biophysics; Carbachol; Cerebral Cortex; Cholinergic Agonists; Drug Combinations; Electric Stimulation; Epilepsy; Excitatory Postsynaptic Potentials; Female; Humans; In Vitro Techniques; Male; Muscarinic Antagonists; Patch-Clamp Techniques; Pirenzepine; Pyridines; Receptors, Muscarinic; Thiadiazoles | 2012 |
A role for M(2) and M(3) muscarinic receptors in the contraction of rat and human small airways.
Topics: Animals; Carbachol; Cholinergic Agonists; Humans; In Vitro Techniques; Lung; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Scopolamine Derivatives; Tiotropium Bromide | 2013 |
Muscarinic depolarization of layer II neurons of the parasubiculum.
Topics: Animals; Anthracenes; Carbachol; Cholinergic Agonists; Diamines; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Male; Membrane Potentials; Muscarinic Antagonists; Neurons; Parasympatholytics; Pirenzepine; Pyramidal Cells; Rats; Rats, Long-Evans; Receptor, Muscarinic M1 | 2013 |
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases.
Topics: Aged; Atropine; Benzofurans; Carbachol; Cell Proliferation; Cells, Cultured; Cholinergic Agonists; Gene Expression; Humans; Male; Mitogen-Activated Protein Kinases; Muscarinic Antagonists; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Piperidines; Pirenzepine; Proto-Oncogene Proteins c-akt; Pyrrolidines; Receptors, Muscarinic; RNA, Messenger; Urinary Bladder | 2013 |
Monitoring intracellular calcium in response to GPCR activation using thin-film silicon photodiodes with integrated fluorescence filters.
Topics: Biosensing Techniques; Calcium; Carbachol; Fluorescence; HEK293 Cells; Humans; Microfluidic Analytical Techniques; Pirenzepine; Receptor, Muscarinic M1; Silicon | 2014 |
Age-related peculiarities of inotropic response of rat myocardium to selective block of M1-cholinoreceptors.
Topics: Age Factors; Aging; Animals; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; Depression, Chemical; Heart Atria; Heart Ventricles; In Vitro Techniques; Myocardial Contraction; Pirenzepine; Rats; Receptor, Muscarinic M1 | 2013 |
Regulation of persistent activity in hippocampal mossy cells by inhibitory synaptic potentials.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Animals, Newborn; Carbachol; Cholinergic Agonists; Electric Stimulation; Excitatory Amino Acid Agents; Hippocampus; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Muscarinic Agonists; Muscarinic Antagonists; Nerve Fibers; Pirenzepine; Pyramidal Cells; Rats; Rats, Sprague-Dawley | 2014 |
Carbachol-induced network oscillations in an in vitro limbic system brain slice.
Topics: Animals; CA3 Region, Hippocampal; Carbachol; Cholinergic Agonists; Entorhinal Cortex; Hippocampus; Male; Muscarinic Antagonists; Nerve Net; Neurons; Pirenzepine; Rats; Rats, Sprague-Dawley; Theta Rhythm | 2017 |
Role of rho-kinase (ROCK) in tonic but not phasic contraction in the frog stomach smooth muscle.
Topics: Amides; Animals; Atropine; Carbachol; Gastric Mucosa; Muscle Contraction; Muscle, Smooth; Nifedipine; Organ Culture Techniques; Pirenzepine; Pyridines; Ranidae; rho-Associated Kinases | 2018 |
Central muscarinic receptor subtypes (M1 and M3) involved in carbacol-induced hypophagia in neonatal broiler chicken.
Topics: Animals; Animals, Newborn; Behavior, Animal; Carbachol; Chickens; Disease Models, Animal; Eating; Injections, Intraventricular; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M3 | 2020 |
Monitoring Intracellular Calcium in Response to GPCR Activation: Comparison Between Microtiter Plates and Microfluidic Assays.
Topics: Animals; Calcium; Carbachol; Cholinergic Agonists; HEK293 Cells; Humans; Microfluidics; Muscarinic Antagonists; Pirenzepine; Receptor, Muscarinic M1; Receptors, G-Protein-Coupled; Signal Transduction | 2021 |