carbachol has been researched along with piperidines in 246 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (15.04) | 18.7374 |
| 1990's | 109 (44.31) | 18.2507 |
| 2000's | 71 (28.86) | 29.6817 |
| 2010's | 28 (11.38) | 24.3611 |
| 2020's | 1 (0.41) | 2.80 |
| Authors | Studies |
|---|---|
| Alioto, RL; Eash, JR; Krebs, JB; Mir, GN; Sperow, JW; Yelnosky, J | 1 |
| Changeux, JP; Kato, G | 1 |
| Kashima, K; Kataoka, K; Kato, M; Kuriyama, K; Ohkuma, S | 1 |
| Sastry, BV; Stephan, CC | 1 |
| Abdallah, EA; Eldefrawi, AT; Eldefrawi, ME; Jett, DA | 1 |
| Bado, A; Cherifi, Y; Le Romancer, M; Lewin, MJ; Pigeon, C; Reyl-Desmars, F | 1 |
| Buchan, AM; Kwok, YN; MacLeod, MD; Meloche, RM | 1 |
| Bado, A; Laigneau, JP; Lewin, MJ; Moizo, L | 1 |
| Bungardt, E; Feifel, R; Lambrecht, G; Moser, U; Mutschler, E; Surprenant, A; Tacke, R; Vockert, E | 1 |
| Martin, JR | 1 |
| Barlow, RB; Christophe, J; Renzetti, AR; Tastenoy, M; Waelbroeck, M | 1 |
| Funakoshi, A; Jimi, A; Kono, A; Tateishi, K; Tsuru, M; Wakasugi, H | 1 |
| Buyse, MA; Fraeyman, NH; Lefebvre, RA | 1 |
| Pechnick, RN; Vargas, HM | 1 |
| Challiss, RA; Nahorski, SR; Whitham, EM | 1 |
| Courtney, MJ; Nicholls, DG | 1 |
| Bagetta, G; Constanti, A | 1 |
| Cheung, CL; De Boer, T; Tonnaer, JA | 1 |
| Daniel, EE; Janssen, LJ | 1 |
| Donoff, B; Lad, R; Rangachari, PK | 1 |
| Alonso, MJ; Arribas, S; Balfagón, G; Marín, J; Salaices, M | 1 |
| Chiba, S; Furukawa, Y; Nakane, T | 1 |
| Costa, G; Massi, M; Melchiorre, C; Perfumi, M; Polidori, C; Sajia, A | 1 |
| Hersey, SJ; Kajimura, M; Sachs, G; Scott, DR; Wilkes, JM | 1 |
| Benedito, S; García-Sacristán, A; Hernández, M; Prieto, D; Rivera, L | 1 |
| Richards, MH | 1 |
| Endou, M | 1 |
| Aihara, H; Isobe, Y; Muramatsu, M; Otomo, S | 1 |
| Igata, H; Nishida, T; Okabe, S; Takagi, K | 1 |
| Yang, CM | 1 |
| Massi, M; Melchiorre, C; Perfumi, M; Polidori, C; Pompei, PL | 1 |
| Alger, BE; Pitler, TA | 1 |
| Harbon, S; Leiber, D; Marc, S | 1 |
| Fleming, N; Laniyonu, A; Sliwinski-Lis, E | 1 |
| Bloom, JW; Lai, J; Roeske, WR; Yamamura, HI | 1 |
| Beinfeld, MC; Brog, JS | 1 |
| Hanack, C; Herawi, M; Kopp, R; Lambrecht, G; Moser, U; Mutschler, E; Pfeiffer, A; Tacke, R | 1 |
| Akahane, K; Chiba, S; Furukawa, Y; Karasawa, Y | 1 |
| Gilani, AU | 1 |
| Choo, LK; Darroch, SA; Mitchelson, F; Taylor, WC | 1 |
| Daly, JW; Gusovsky, F; Hollingsworth, EB | 1 |
| Brown, DR; Chang, EB; Field, M; Wang, NS | 1 |
| Cohen-Armon, M; Sokolovsky, M | 1 |
| Cohen-Armon, M; Henis, YI; Kloog, Y; Sokolovsky, M | 1 |
| Ghataorre, AS; Lambert, DG; Nahorski, SR | 1 |
| Syed, M; Tokuno, H; Tomita, T | 1 |
| Diener, M; Knobloch, SF; Rummel, W | 1 |
| Adeagbo, AS; Magbagbeola, AO | 1 |
| Fowler, CJ; Thorell, G | 1 |
| Roger, T; Ruckebusch, Y | 1 |
| Funakoshi, A; Kitani, K; Miyasaka, K; Shinozaki, H | 1 |
| Sokolovsky, M; van Koppen, CJ | 1 |
| Davidesko, D; Doods, HN; Rinner, I; van Charldorp, KJ; van Zwieten, PA | 1 |
| Cobbin, LB; Gilani, SA | 1 |
| Bali, JP; Baudiere, B; Giraldo, E; Ladinsky, H; Monferini, E | 1 |
| Barbieri, RL; Gochberg, J; Ryan, KJ | 1 |
| Marshall, IG; Parsons, SM; Whitton, PS | 1 |
| Barenholz, Y; Henis, YI; Moscona-Amir, E; Sokolovsky, M; Yechiel, E | 1 |
| Eglen, RM; Whiting, RL | 1 |
| Barlow, RB; Shepherd, MK | 1 |
| Terrar, DA | 1 |
| Bonta, IL; Saxena, PR | 1 |
| Eichele, O; Mutschler, E | 1 |
| Gandiha, A; Marshall, IG | 1 |
| Fabian, K; Mörsdorf, K; Vahlensieck, W | 1 |
| Mörsdorf, K; Wengenroth, H | 1 |
| Aust, G; Van Zwieten, PA | 1 |
| Thron, CD; Waud, DR | 1 |
| Madill, HD; Savoie, ML; Stewart, WC | 1 |
| Baron, B; Kloog, Y | 1 |
| Frey, HH; Reiche, R | 1 |
| Bonfilio, AC; Jacoby, HI; Mills, JE; Rasmussen, CR; Scott, MK | 1 |
| Bartfai, T; Hedlund, B; Lundberg, JM | 1 |
| Bartfai, T; Hedlund, B; Järv, J | 1 |
| Coupar, IM; McLean, PG | 1 |
| Mitchelson, F; Shen, A | 1 |
| Hackmiller, RC; Jumblatt, JE | 1 |
| Ernsberger, P; Evinger, MJ; Joh, TH; Regunathan, S; Reis, DJ | 1 |
| Bristow, DR; Dupere, JR; Zamani, MR | 1 |
| Imaizumi, Y; Kawai, T; Masuda, Y; Ryang, S; Tanaka, M; Watanabe, M; Yamahara, NS | 1 |
| Maggio, R; Nanavati, S; Vogel, Z; Wess, J | 1 |
| Bertrand, C; Bunnett, NW; Debas, HT; Geppetti, P; Huber, O; Nadel, JA; Pellegrini, CA | 1 |
| Classen, M; Schaffer, K; Schepp, W; Schusdziarra, V; Wegner, U; Weigert, N | 1 |
| De Giorgio, R; Giachetti, A; Maggi, CA; Patacchini, R | 1 |
| Gabelt, BT; Kaufman, PL; Poyer, JF | 1 |
| Fukui, H; Inagaki, N; Kondou, H | 1 |
| Ko, FN; Lin, CH; Teng, CM; Wu, YC; Yang, CM | 1 |
| DelValle, J; Park, J; Yamada, T; Yokotani, K | 1 |
| Erwin, VG; Radcliffe, RA | 1 |
| Barzaghi, F; Bonetti, C; Cesana, R; Fortin, M; Galliani, G; Hunt, P; Maggioni, A; Nencioni, A; Parini, C; Toja, E | 1 |
| Dauphin, F; Hamel, E; Linville, DG | 1 |
| Bobbin, RP; Erostegui, C; Norris, CH | 1 |
| Blüml, K; Mutschler, E; Wess, J | 1 |
| Angeli, P; Bianchi, S; Imeri, L; Mancia, M | 1 |
| Fisher, L; Hall, S; Pennefather, JN | 1 |
| Chuang, DM; Fukamauchi, F; Hough, C; Saunders, PA | 1 |
| Maggio, R; Vogel, Z; Wess, J | 1 |
| Consolo, S; Garcia Ruiz, AJ; La Porta, C; Ladinsky, H; Zambelli, M | 1 |
| Fain, JN; Sallés, J; Wallace, MA | 1 |
| Tonnaer, JA; van Huizen, F | 1 |
| Shiraishi, K; Takayanagi, I | 1 |
| Bado, A; Cherifi, Y; Laigneau, JP; Lewin, MJ; Moizo, L | 1 |
| Gean, PW; Hsu, KS; Huang, CC | 1 |
| Garland, CJ; Hillier, K; Kerr, PM; Wallis, RM | 1 |
| Sjögren, C; Tobin, G | 1 |
| Bartolini, A; Galeotti, N; Ghelardini, C; Gualtieri, F; Teodori, E | 1 |
| De Neef, P; Domenach, V; Vandermeers, A; Vandermeers-Piret, MC; Waelbroeck, M | 1 |
| de la Vega, MT; Montano, JA; Nunez, A | 1 |
| Bilezikian, JP; Huber, F; Robinson, RB; Steinberg, SF; Sun, LS; Vulliemoz, Y | 1 |
| Tobin, G | 1 |
| Benavente, V; Botey, J; Eseverri, JL; Marin, A | 1 |
| Buchan, AM; Koop, I; Meloche, RM; Squires, PE | 1 |
| Gillespie, JI; Slater, BJ; Varma, JS | 1 |
| Hsu, KS; Huang, CC; Yang, CH | 1 |
| Arana, R; Bacman, S; Borda, E; Camusso, JJ; Hubscher, O; Sterin-Borda, L | 1 |
| Onoe, H; Sakai, K | 1 |
| Murayama, T; Nomura, Y; Yamada, T | 1 |
| Aronstam, RS; Puhl, HL; Raman, PS; Williams, CL | 1 |
| Levin, RJ; Przyborski, SA | 1 |
| Semba, K; White, TD | 1 |
| Arias-Montaño, JA; de la Vega, MT; Nuñez, A | 1 |
| Bolton, TB; Zholos, AV | 1 |
| Hara, Y; Nakaya, H; Tamagawa, M; Watanabe, Y | 1 |
| Alfonzo, MJ; de Alfonzo, RG; de Becemberg, IL; de Herrera, VN; de Villaroel, SS; Misle, AJ | 1 |
| Baba, H; Goldstein, PA; Kohno, T; Okamoto, M; Shimoji, K; Yoshimura, M | 1 |
| Cobuzzi, A; Lai, FM; Spinelli, W | 1 |
| Komori, S; Nakayama, T; Ohashi, H; Unno, T | 1 |
| Laurier, LG; Preiksaitis, HG | 1 |
| Dement, WC; Mignot, E; Nishino, S; Reid, MS; Siegel, JM; Tafti, M | 1 |
| Blumenthal, JA; Carey, HV; Onorato, JJ | 1 |
| Galas, L; Garnier, M; Lamacz, M; Lenglet, S; Tonon, MC; Vaudry, H | 1 |
| Chew, CS; Flemström, G; Säfsten, B | 1 |
| Hiley, CR; White, R | 1 |
| Aureggi, G; Croci, T; Ferla, G; Guagnini, F; Le Fur, G; Maffrand, JP; Manara, L; Mukenge, S; Rinaldi-Carmona, M | 1 |
| Harris, D; Kendall, DA; Randall, MD | 1 |
| Hara, T; Iwanaga, S; Makita, T; Shibata, O; Shibata, S; Sumikawa, K; Tsuda, A | 1 |
| Braverman, A; Legos, J; Luthin, G; Ruggieri, M; Young, W | 1 |
| Haapalinna, A; Larson, J; Niittykoski, M; Ruotsalainen, S; Sirviö, J | 1 |
| Cross, AJ; De Souza, RJ; Green, AR; Misra, A; Murray, TK; Snape, MF; Williams, JL | 1 |
| Damer, V; Krichevsky, VP; Pagala, MK; Vaydovsky, I; Wise, GJ | 1 |
| Erickson, KA; Schroeder, A; Zhang, X | 1 |
| Bernardi, G; Bonci, A; Grillner, P; Mercuri, NB; Svensson, TH | 1 |
| Baiardi, P; Lucchelli, A; Masoero, E; Santagostino-Barbone, MG; Tonini, M | 1 |
| Acs, Z; Makara, GB; Némethy, Z | 1 |
| Arellano, RO; Garay, E; Miledi, R | 1 |
| Feldman, JL; Shao, XM | 1 |
| Kouznetsova, M; Nistri, A | 1 |
| Eglen, RM; Luong, LA; MacLennan, SJ; Martin, GR; Martin, RS; Welsh, NJ | 1 |
| Lau, WA; Mitchelson, FJ; Pennefather, JN | 1 |
| Emala, CW; Fehr, JJ; Hirshman, CA | 1 |
| Andersson, K; Fujiwara, M; Persson, K | 1 |
| Malomough, A; Naumenko, N; Nikolsky, E; Urazaev, A; Vyskocil, F | 1 |
| Levendusky, M; Longhurst, PA | 1 |
| Kim, D; Moore, BA; Vanner, S | 1 |
| Chapple, CR; Chess-Williams, R; Yamanishi, T; Yasuda, K | 1 |
| Hashimoto, S; Iwanaga, S; Makita, T; Saito, M; Shibata, O; Sumikawa, K; Tsuda, A | 1 |
| Chapple, CR; Chess-Williams, R; Couldwell, C; Sellers, DJ; Yamanishi, T; Yasuda, K | 1 |
| Barrett, KE; Kahn, ME; Sausville, EA; Senderowicz, A | 1 |
| Daniels, DV; Eglen, RM; Ford, AP; Hegde, SS; Meloy, TD | 1 |
| Dohi, S; Ishizawa, Y; Ma, HC; Wang, YF; Yanagidate, F | 1 |
| Kadota, H; Kuwahara, M; Mikami, H; Nishibata, R; Tsubone, H | 1 |
| Franco, W; Leite, RS | 1 |
| Bosmans, JP; Briejer, MR; Heylen, L; Jurzak, M; Leysen, JE; Prins, NH; Schuurkes, JA; Van Daele, P | 1 |
| Choppin, A; Eglen, RM | 1 |
| Herzog, M; Liu, J; Scherer, EQ; Scofield, MA; Shimozono, M; Wangemann, P | 1 |
| Delbro, DS; Giglio, D; Tobin, G | 1 |
| Fujikawa, T; Kimura, T; Mase, T; Noguchi, K; Numazawa, T; Ohtake, N; Sagara, T; Sagara, Y | 1 |
| Pérez Leirós, C; Rosignoli, F | 1 |
| Huang, SC | 1 |
| Furness, JB; Kumano, K; Kunze, WA; Larsson, H; Murr, E; Vogalis, F | 1 |
| Braverman, AS; Ruggieri, MR; Tallarida, RJ | 1 |
| Alger, BE; Isokawa, M; Kim, J; Ledent, C | 1 |
| Fukumori, R; Goshima, Y; Hagiwara, Y; Kanaya, T; Kubo, T; Okatani, H | 2 |
| Alsasua, A; Benhamú, B; Girón, R; López-Rodríguez, ML; Martín, MI; Pascual, D | 1 |
| Choi, KH; Jeon, JH; Kang, TM; Kim, HJ; Kim, IG; Kim, KW; Kim, SJ; Min, KW; Park, KH; So, I; Yang, DK | 1 |
| Bernardino, CR; Chang, EL; Dartt, DA; Hodges, RR; Horikawa, Y; Rios, JD; Rubin, PA; Shatos, MA; Zoukhri, D | 1 |
| Borda, E; Busch, L | 1 |
| Bordi, F; Costa, LG; Dieguez-Acuña, FJ; Guizzetti, M; Madia, F; Vitalone, A; Woods, JS | 1 |
| BENNETT, PB | 1 |
| Harada, N; Makita, T; Niwa, M; Saito, M; Shibata, O; Sumikawa, K; Yamaguchi, M; Yoshimura, M | 1 |
| Caruso, ML; De Ponti, F; Demma, I; Guerra, V; Lorusso, D; Maselli, MA; Pezzolla, F; Piepoli, AL | 1 |
| Crittenden, EL; García, DM; González, A | 1 |
| Borroni, B; Cattabeni, F; Colciaghi, F; Di Luca, M; Gardoni, F; Marcello, E; Padovani, A; Zimmermann, M | 1 |
| Borda, E; Orman, B; Reina, S; Sterin-Borda, L | 1 |
| Boxberger, M; Choritz, L; Krauss, A; Meissner, S; Rosenthal, R; Stumpff, F; Thieme, H; Wiederholt, M | 1 |
| Blaha, CD; Miller, AD | 1 |
| Borda, ES; Orman, B; Reina, S; Sterin-Borda, L | 1 |
| Izumi, Y; Komori, S; Matsuyama, H; Okamoto, H; Sakamoto, T; Uchiyama, M; Unno, T; Wess, J; Yamada, M | 1 |
| Alger, BE; Jones, LM; Karnup, SV; Karson, MA; Reich, CG | 1 |
| Forrest, AS; Ordög, T; Sanders, KM | 1 |
| Paulose, CS; Renuka, TR; Savitha, B | 1 |
| Hattori, M; Komori, S; Matsuyama, H; Nishimura, M; Sakamoto, T; Uchiyama, M; Unno, T | 1 |
| de Groat, WC; Ng, YK; Wu, HY | 1 |
| Arias-Montaño, JA; Sánchez-Lemus, E | 1 |
| Miyazu, M; Ohinata, H; Sugawara, R; Takai, A; Takai, Y; Yoshida, A | 1 |
| Braverman, AS; Ruggieri, MR | 1 |
| Braeter, M; Hakenberg, OW; Kelly, LU; Ravens, U; Waelbroeck, M; Weiss, A; Wuest, M | 1 |
| Cao, J; Hashiba, K; Kitazawa, T; Komori, S; Taneike, T; Unno, T; Wess, J; Yamada, M | 1 |
| Chapple, CR; Chess-Williams, R; Stevens, LA | 1 |
| Hirose, K; Kaeriyama, S; Muramatsu, A; Nouchi, H; Sato, M; Shigenobu, K; Shimizu, N; Tanaka, H | 1 |
| De Ridder, D; Gevaert, T; Hutchings, G; Nilius, B; Vandepitte, J; Vriens, J | 1 |
| Alves, FH; Corrêa, FM; Crestani, CC; Resstel, LB | 1 |
| Ehlert, FJ; Figueroa, KW; Griffin, MT; Liller, S | 1 |
| Cloutier, S; Richter, M; Sirois, P | 1 |
| Finney, SM; Gillespie, JI; Stewart, LH | 1 |
| Lemtiri-Chlieh, F; Levine, ES | 1 |
| Andersson, M; Aronsson, P; Delbro, DS; Giglio, D; Haraldsson, B; Tobin, G | 1 |
| Korolkiewicz, RP; Sein-Anand, J; Sokołowska-Wojdyło, M; Umer, A; Włodarkiewicz, A; Ługowska-Umer, H | 1 |
| Chen, H; Chen, YH; Li, J; Li, L; Liang, L; Liu, X; Liu, Y; Ma, J; Peng, L; Qi, J; Wu, X; Xiao, J; Xu, J; Yang, Y; Zhang, Y; Zhao, C | 1 |
| Boone, TB; Lai, HH; Munoz, A; Smith, CP; Somogyi, GT; Szigeti, GP | 1 |
| Anhê, G; Barbosa, HC; Bordin, S; Borelli, MI; Boschero, AC; Bowe, J; Gagliardino, JJ; Persaud, SJ | 1 |
| Alves-Faria, P; Amaral, M; Falcão-Reis, F; Leite-Moreira, AF; Rocha-Sousa, A; Saraiva, J | 1 |
| Atorino, G; Aviello, G; Borrelli, F; Capasso, R; Pagano, E; Romano, B | 1 |
| Eda, H; Kimura, N; Komada, T; Mikami, T; Naganeo, R; Nakata, E; Nakatani, K; Ohmi, T; Sakakibara, M; Sugimoto, H; Suzuki, K; Toga, T | 1 |
| Aydin, B; Cabadak, H; Kan, B; Küçükibrahimoğlu, E; Zafer Gören, M | 1 |
| Choi, S; Choi, SJ; Jun, JY; Kim, SH; Parajuli, SP; So, KY; Sohn, HM; Yeum, CH; Yoon, PJ | 1 |
| Kaba, H; Takahashi, Y | 1 |
| Amici, M; Cho, K; Collingridge, GL; Dickinson, BA; Futai, K; Jo, J; Kim, MJ; Lee, YB; Sheng, M; Son, GH; Whitcomb, DJ; Winters, BL | 1 |
| Haghparast, A; Hassanpour-Ezatti, M; Safari, MS; Taslimi, Z | 1 |
| Ami, N; Fushiki, H; Koga, K; Ogino, Y; Ohta, H; Ueno, Y | 1 |
| Boone, TB; Lai, HH; Munoz, A; Smith, CP; Somogyi, GT | 1 |
| Britton, FC; Koh, SD; O'Driscoll, K; Sanders, KM; Sung, IK; Sung, TS; Zheng, H; Zhu, MH | 1 |
| Barnes, PJ; Brown, SM; Chana, KK; Donnelly, LE; Fenwick, PS; Koarai, A; Nicholson, AG; Russell, RE; Traves, SL | 1 |
| Altun, A; Bagcivan, I; Durmus, N; Kaya, T; Sarac, B; Sencan, M; Turan, M | 1 |
| Chess-Williams, R; Moro, C; Uchiyama, J | 1 |
| Browning, C; Clark, KL; Connor, HE; Ford, AJ; Hall, DA; Hodgson, ST; Luttmann, MA; Russell, LJ; Saunders, KA; Slack, RJ | 1 |
| Henry, PJ; Mann, TS; Taylor, SJ | 1 |
| Kajioka, S; Naito, S; Seki, N; Shahab, N | 1 |
| Andersson, M; Aronsson, P; Doufish, D; Lampert, A; Tobin, G | 1 |
| Lograno, MD; Romano, MR | 1 |
| Barnes, PJ; Brown, SM; Donnelly, LE; Koarai, A; Nicholson, AG; Sturton, RG | 1 |
| Ambudkar, I; Cotrim, A; Liu, X; Mitchell, J; Mori, Y; Swaim, W; Teos, L; Zheng, C | 1 |
| Arrighi, N; Bodei, S; Cosciani Cunico, S; Michel, MC; Sigala, S; Simeone, C; Spano, P; Zani, D | 1 |
| Parajuli, SP; Petkov, GV | 1 |
| Jackson, MW; Park, K; Park, S | 1 |
| Andersson, KE; Campeau, L; Füllhase, C; Gratzke, C; Hedlund, P; Hennenberg, M; Sibaev, A; Stief, C; Storr, M | 1 |
| Deng, J; Li, L; Shi, C; Song, B; Wu, Y; Zhang, X | 1 |
| de Guzman, G; Freestone, PS; Lipski, J; Wu, XH | 1 |
| Haghparast, A; Jahangirvand, M; Moradi, M; Pirasteh, AH; Yazdi, F | 1 |
| Esmaeili, MH; Ezzatpanah, S; Haghparast, A; Reisi, Z | 2 |
| Brown, RE; McKenna, JT; Yang, C | 1 |
| Al-Ayed, MSZ | 1 |
| Agnetta, L; Bermudez, M; Decker, M; Gerwe, H; Holze, J; Irmen, M; Littmann, T; Schramm, S; Tränkle, C; Wolber, G | 1 |
| Hassanpour, S; Lankarani Mohajer, L; Zendehdel, M | 1 |
1 review(s) available for carbachol and piperidines
| Article | Year |
|---|---|
Pharmacology and second messenger interactions of cloned muscarinic receptors.
Topics: Animals; Atropine; Carbachol; Cell Line; Humans; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic; Recombinant Proteins; Second Messenger Systems; Transfection | 1991 |
1 trial(s) available for carbachol and piperidines
| Article | Year |
|---|---|
[Ebastine : treatment of perennial rhinitis in the child].
Topics: Adolescent; Butyrophenones; Carbachol; Child; Conjunctivitis, Allergic; Female; Histamine H1 Antagonists; Humans; Male; Nasal Provocation Tests; Piperidines; Rhinitis, Allergic, Perennial; Skin Tests; Treatment Outcome | 1996 |
244 other study(ies) available for carbachol and piperidines
| Article | Year |
|---|---|
In vivo antimotility and antidiarrheal activity of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent. Comparison with diphenoxylate and loperamide.
Topics: Amidines; Animals; Antidiarrheals; Carbachol; Charcoal; Cholera Toxin; Diarrhea; Diphenoxylate; Feces; Gastrointestinal Motility; Isonipecotic Acids; Loperamide; Male; Piperidines; Prostaglandins E; Rats; Serotonin; Stomach | 1978 |
Studies on the effect of histrionicotoxin on the monocellular electroplax from Electrophorus electricus and on the binding of (3H)acetylcholine to membrane fragments from Torpedo marmorata.
Topics: Alkynes; Animals; Carbachol; Diaphragm; Eels; Electric Organ; Electrophorus; In Vitro Techniques; Phrenic Nerve; Piperidines; Rats; Receptors, Drug; Toxins, Biological | 1976 |
Characterization of muscarinic receptor subtypes on rat pancreatic acini: pharmacological identification by secretory responses and binding studies.
Topics: Amylases; Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Male; Pancreas; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sincalide | 1992 |
Characterization of the subtype of muscarinic receptor coupled to the stimulation of phosphoinositide hydrolysis in 132-1N1 human astrocytoma cells.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Astrocytoma; Atropine; Carbachol; Diamines; Humans; Hydrolysis; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine; Tumor Cells, Cultured | 1992 |
Differential effects of paraoxon on the M3 muscarinic receptor and its effector system in rat submaxillary gland cells.
Topics: Animals; Atropine; Binding Sites; Carbachol; Cyclic AMP; Hydrolysis; Male; Paraoxon; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Regression Analysis; Submandibular Gland | 1992 |
Purification of a histamine H3 receptor negatively coupled to phosphoinositide turnover in the human gastric cell line HGT1.
Topics: Binding Sites; Carbachol; Cholera Toxin; Chromatography, Affinity; Chromatography, Gel; Guanosine 5'-O-(3-Thiotriphosphate); Histamine Antagonists; Humans; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Methylhistamines; Molecular Weight; Phosphatidylinositols; Piperidines; Receptors, Histamine; Receptors, Histamine H3; Stomach Neoplasms; Tumor Cells, Cultured | 1992 |
Muscarinic regulation of somatostatin release from primary cultures of human antral epithelial cells.
Topics: Adult; Carbachol; Cells, Cultured; Epithelium; Female; Humans; Male; Methacholine Chloride; Parasympatholytics; Piperidines; Pyloric Antrum; Radioimmunoassay; Receptors, Muscarinic; Somatostatin | 1992 |
Pharmacological characterization of histamine H3 receptors in isolated rabbit gastric glands.
Topics: Aminopyrine; Animals; Carbachol; Gastric Mucosa; Histamine; Histamine Release; In Vitro Techniques; Male; Methylhistamines; Piperidines; Rabbits; Ranitidine; Receptors, Histamine H1 | 1992 |
Characterization of muscarinic receptors mediating vasodilation in guinea-pig ileum submucosal arterioles by the use of computer-assisted videomicroscopy.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arterioles; Benzodiazepinones; Carbachol; Guinea Pigs; Ileum; Methacholine Chloride; Muscarine; Muscarinic Antagonists; Oxotremorine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Prostaglandin Endoperoxides, Synthetic; Receptors, Muscarinic; Vasodilation | 1992 |
Pressor response to posterior hypothalamic administration of carbachol is mediated by muscarinic M3 receptor.
Topics: Animals; Atropine Derivatives; Blood Pressure; Carbachol; Diamines; Dose-Response Relationship, Drug; Hypothalamus, Posterior; Kinetics; Male; Microinjections; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1992 |
Inactivation of brain cortex muscarinic receptors by 4-diphenylacetoxy-1-(2-chloroethyl) piperidine mustard.
Topics: Animals; Carbachol; Cerebral Cortex; Diphenylacetic Acids; Muscarinic Antagonists; Myocardium; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1992 |
Acetylcholine regulates pancreastatin secretion from the human pancreastatin-producing cell line (QGP-1N).
Topics: Acetylcholine; Adenoma, Islet Cell; Atropine; Calcimycin; Calcium; Carbachol; Chromogranin A; Gastrin-Releasing Peptide; Humans; Pancreatic Hormones; Pancreatic Neoplasms; Parasympatholytics; Peptides; Piperidines; Pirenzepine; Receptors, Muscarinic; Sincalide; Tumor Cells, Cultured | 1991 |
Study of the muscarinic receptor subtypes in N1E 115 mouse neuroblastoma cells.
Topics: Animals; Carbachol; Cyclic AMP; Cyclic GMP; Indicators and Reagents; Ligands; Mice; Neuroblastoma; Parasympatholytics; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tumor Cells, Cultured | 1991 |
Binding affinity and antimuscarinic activity of sigma and phencyclidine receptor ligands.
Topics: Animals; Binding, Competitive; Carbachol; Cerebral Cortex; Dioxolanes; Guinea Pigs; Haloperidol; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Pentazocine; Phosphatidylinositols; Piperidines; Receptors, Muscarinic; Receptors, Neurotransmitter; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Phencyclidine; Scopolamine Derivatives | 1991 |
M3 muscarinic cholinoceptors are linked to phosphoinositide metabolism in rat cerebellar granule cells.
Topics: Animals; Animals, Newborn; Binding, Competitive; Carbachol; Cerebellum; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Male; Parasympatholytics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Metabotropic receptor-mediated regulation of cytoplasmic free calcium in cultured cerebellar granule cells.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Carbachol; Cells, Cultured; Cerebellum; Cycloleucine; Cytoplasm; Ibotenic Acid; Kinetics; N-Methylaspartate; Neurotoxins; Piperidines; Quisqualic Acid; Receptors, Neurotransmitter | 1991 |
Muscarinic inhibition of excitatory neurotransmission in guinea-pig olfactory cortex slices: weak antagonism by M3-muscarinic receptor antagonists.
Topics: Action Potentials; Animals; Carbachol; Cerebral Cortex; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Olfactory Bulb; Parasympatholytics; Piperidines; Receptors, Muscarinic; Synaptic Transmission | 1991 |
cGMP formation and phosphoinositide turnover in rat brain slices are mediated by pharmacologically distinct muscarinic acetylcholine receptors.
Topics: Animals; Atropine; Brain; Carbachol; Cyclic GMP; Guanylate Cyclase; Hippocampus; Inositol Phosphates; Male; Nitroprusside; Phosphatidylinositols; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Succinimides | 1991 |
Pre- and postjunctional muscarinic receptors in canine bronchi.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol Compounds; Bronchi; Carbachol; Dogs; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1990 |
Functional subtyping of muscarinic receptors on canine esophageal mucosa.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Amiloride; Animals; Atropine; Carbachol; Chlorides; Dogs; Electric Conductivity; Esophagus; Female; In Vitro Techniques; Ion Channels; Male; Membrane Potentials; Mucous Membrane; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Sodium | 1991 |
Presynaptic M2-muscarinic receptors on noradrenergic nerve endings and endothelium-derived M3 receptors in cat cerebral arteries.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Carbachol; Cats; Cerebral Arteries; Endothelium, Vascular; Female; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasodilation | 1991 |
Anti-muscarinic effect of alinidine on acetylcholine-induced vasodilation in isolated and perfused dog coronary arteries.
Topics: Acetylcholine; Animals; Carbachol; Clonidine; Coronary Vessels; Dogs; Female; In Vitro Techniques; Male; Parasympatholytics; Piperidines; Pirenzepine; Vasodilation | 1991 |
The release of atrial natriuretic factor induced by central carbachol injection may be mediated by muscarinic M1 receptors.
Topics: Animals; Atrial Natriuretic Factor; Brain; Carbachol; Diamines; Dose-Response Relationship, Drug; Injections, Intraventricular; Injections, Subcutaneous; Male; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Muscarinic responses of gastric parietal cells.
Topics: Aminopyrine; Animals; Arachidonic Acids; Calcium; Carbachol; Glucose; Image Processing, Computer-Assisted; Ionomycin; N-Methylscopolamine; Parasympatholytics; Parietal Cells, Gastric; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1991 |
Distribution and function of cholinergic receptors in the sheep detrusor muscle.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Atropine; Carbachol; Cholinesterase Inhibitors; Ganglia, Parasympathetic; Male; Muscle Contraction; Muscle, Smooth; Nerve Tissue Proteins; Piperidines; Pirenzepine; Receptors, Muscarinic; Sheep; Tetraisopropylpyrophosphamide; Urinary Bladder | 1991 |
[Pharmacological analysis of drug interactions of disopyramide and its congeners with peripheral muscarinic acetylcholine receptors].
Topics: Animals; Binding, Competitive; Carbachol; Disopyramide; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Myocardial Contraction; N-Methylscopolamine; Piperidines; Propylamines; Pyridines; Receptors, Muscarinic; Scopolamine Derivatives | 1991 |
H2-receptor antagonism by a novel compound IT-066 assessed from [14C]aminopyrine accumulation in rabbit parietal cells.
Topics: Aminopyrine; Animals; Anti-Ulcer Agents; Bucladesine; Carbachol; Cimetidine; Famotidine; Gastric Mucosa; Histamine; Histamine H2 Antagonists; In Vitro Techniques; Male; Piperidines; Pyridines; Rabbits | 1990 |
[Effects of IT-066, a new histamine H2-receptor antagonist, on gastric acid secretion and experimental gastric ulcers in rats and dogs].
Topics: Acetates; Animals; Anti-Ulcer Agents; Carbachol; Depression, Chemical; Dogs; Famotidine; Female; Gastric Acid; Histamine Antagonists; Histamine H2 Antagonists; Male; Pentagastrin; Piperidines; Pyridines; Rats; Rats, Inbred Strains; Stomach Ulcer | 1990 |
Characterization of muscarinic receptors in dog tracheal smooth muscle cells.
Topics: Animals; Atropine; Carbachol; Diamines; Dogs; In Vitro Techniques; Kinetics; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives; Trachea | 1991 |
Natriuresis, kaliuresis and antidiuresis induced by central carbachol injection are mediated by muscarinic M1 receptors.
Topics: Animals; Carbachol; Diamines; Diuresis; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Muscarinic Antagonists; Natriuresis; Piperidines; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
Activation of the pharmacologically defined M3 muscarinic receptor depolarizes hippocampal pyramidal cells.
Topics: Animals; Carbachol; Evoked Potentials; Hippocampus; In Vitro Techniques; Kinetics; Parasympatholytics; Piperidines; Pirenzepine; Pyramidal Tracts; Rats; Receptors, Muscarinic | 1990 |
Pharmacological evidence for distinct muscarinic receptor subtypes coupled to the inhibition of adenylate cyclase and to the increased generation of inositol phosphates in the guinea pig myometrium.
Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Cyclic AMP; Female; Guinea Pigs; In Vitro Techniques; Inositol Phosphates; Myometrium; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic; Type C Phospholipases; Uterine Contraction | 1990 |
Muscarinic M3 receptors are coupled to two signal transduction pathways in rat submandibular cells.
Topics: Animals; Atropine; Carbachol; Cyclic AMP; Parasympatholytics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Signal Transduction; Submandibular Gland | 1990 |
Amplification of the rat M2 muscarinic receptor gene by the polymerase chain reaction: functional expression of the M2 muscarinic receptor.
Topics: Alkaloids; Amino Acid Sequence; Animals; Base Sequence; Carbachol; Cell Line; Cloning, Molecular; Cyclic AMP; Fibroblasts; Furans; Gene Amplification; Gene Expression; Molecular Sequence Data; Muscarinic Antagonists; Naphthalenes; Phosphatidylinositols; Piperidines; Pirenzepine; Plasmids; Polymerase Chain Reaction; Rats; Receptors, Muscarinic; Transfection | 1990 |
Inhibition of carbachol-induced inositol phosphate accumulation by phencyclidine, phencyclidine-like ligands and sigma agonists involves blockade of the muscarinic cholinergic receptor: a novel dioxadrol-preferring interaction.
Topics: Animals; Brain; Carbachol; Culture Techniques; Dibenzocycloheptenes; Dioxolanes; Dizocilpine Maleate; Inositol Phosphates; Male; Phenazocine; Phencyclidine; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Sigma Factor; Transcription Factors | 1990 |
Human gastric mucosa expresses glandular M3 subtype of muscarinic receptors.
Topics: Carbachol; Gastric Mucosa; Humans; In Vitro Techniques; N-Methylscopolamine; Parasympatholytics; Piperazines; Piperidines; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Muscarinic receptor subtypes mediating negative chrono- and inotropic responses in isolated, blood-perfused dog right atria.
Topics: Animals; Atropine; Carbachol; Cardiotonic Agents; Dogs; Electric Stimulation; Female; Heart Atria; Male; Myocardial Contraction; Parasympatholytics; Piperidines; Pirenzepine; Receptors, Muscarinic; Vagus Nerve | 1990 |
Comparison of the rate of occupancy of receptors by anti-cholinergic drugs.
Topics: Alkaloids; Animals; Atropine; Carbachol; Furans; Guinea Pigs; Heart Atria; Ileum; In Vitro Techniques; Naphthalenes; Parasympatholytics; Piperidines; Receptors, Cholinergic | 1990 |
Structure-activity relationships of some Galbulimima alkaloids related to himbacine.
Topics: Alkaloids; Animals; Carbachol; Electric Stimulation; Furans; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Naphthalenes; Parasympatholytics; Piperidines; Plants, Medicinal; Structure-Activity Relationship | 1990 |
Regulation of phosphatidylinositol turnover in brain synaptoneurosomes: stimulatory effects of agents that enhance influx of sodium ions.
Topics: Alkaloids; Animals; Batrachotoxins; Brain; Carbachol; Guinea Pigs; In Vitro Techniques; Indolizines; Ion Channels; Magnesium; Male; Norepinephrine; Ouabain; Phosphatidylinositols; Piperidines; Protein Kinase C; Saxitoxin; Scorpion Venoms; Sodium; Synaptosomes; Tetrodotoxin | 1986 |
Secretagogue-induced changes in membrane calcium permeability in chicken and chinchilla ileal mucosa. Selective inhibition by loperamide.
Topics: Amiloride; Animals; Bombesin; Calcium; Carbachol; Carrier Proteins; Cell Membrane Permeability; Chickens; Chinchilla; Dose-Response Relationship, Drug; Gallopamil; Ileum; Intestinal Mucosa; Loperamide; Neurotensin; Piperidines; Serotonin; Sodium-Hydrogen Exchangers; Substance P; Trifluoperazine | 1986 |
Interactions between the muscarinic receptors, sodium channels, and guanine nucleotide-binding protein(s) in rat atria.
Topics: Acetylcholine; Animals; Batrachotoxins; Benzilates; Carbachol; Dibucaine; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart Atria; Ion Channels; Kinetics; Male; Mathematics; Myocardium; Oxotremorine; Piperidines; Rats; Receptors, Muscarinic; Sodium; Veratridine | 1986 |
Batrachotoxin changes the properties of the muscarinic receptor in rat brain and heart: possible interaction(s) between muscarinic receptors and sodium channels.
Topics: Aconitine; Animals; Batrachotoxins; Benzilates; Binding, Competitive; Brain; Carbachol; Guanylyl Imidodiphosphate; Ion Channels; Kinetics; Macromolecular Substances; Male; Myocardium; Piperidines; Rats; Receptors, Muscarinic; Sodium; Veratridine | 1985 |
Muscarinic receptor binding characteristics of a human neuroblastoma SK-N-SH and its clones SH-SY5Y and SH-EP1.
Topics: Arecoline; Atropine; Carbachol; Cell Membrane; Humans; Neuroblastoma; Piperidines; Pirenzepine; Receptors, Muscarinic; Tumor Cells, Cultured | 1989 |
Effects of cisapride on isolated guinea pig colon.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cisapride; Colon; Electric Stimulation; Female; Guinea Pigs; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Microelectrodes; Muscle, Smooth; Piperidines; Serotonin; Serotonin Antagonists; Tetrodotoxin | 1989 |
Action of loperamide on neuronally mediated and Ca2+- or cAMP-mediated secretion in rat colon.
Topics: Animals; Calcium; Carbachol; Colforsin; Colon; Cyclic AMP; Electric Stimulation; In Vitro Techniques; Intestinal Mucosa; Loperamide; Male; Morphine; Neurons; Piperidines; Rats; Rats, Inbred Strains; Trifluoperazine; Verapamil | 1988 |
Pharmacological actions of ifenprodil in the rat isolated anococcygeus muscle.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium Chloride; Carbachol; In Vitro Techniques; Male; Methoxamine; Muscle Contraction; Muscle, Smooth; Norepinephrine; Piperidines; Potassium Chloride; Rats; Vasodilator Agents | 1985 |
Antagonist effects of the enantiomers of 3-PPP towards alpha 1-adrenoceptors coupled to inositol phospholipid breakdown in the rat cerebral cortex.
Topics: Animals; Antiparkinson Agents; Atropine; Carbachol; Cerebral Cortex; Haloperidol; In Vitro Techniques; Inositol Phosphates; Male; Norepinephrine; Phenoxybenzamine; Piperidines; Prazosin; Raclopride; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Salicylamides; Stereoisomerism; Sugar Phosphates | 1987 |
Prokinetic effects of cisapride, naloxone and parasympathetic stimulation at the equine ileo-caeco-colonic junction.
Topics: Animals; Carbachol; Cecum; Cisapride; Colon; Gastrointestinal Motility; Horses; Ileum; Injections, Intravenous; Metoclopramide; Naloxone; Parasympathomimetics; Pilocarpine; Piperidines | 1988 |
Effects of cisapride on the pancreatic exocrine secretion in rats.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cholecystokinin; Cisapride; In Vitro Techniques; Male; Pancreas; Pancreatic Juice; Piperidines; Proglumide; Rats; Rats, Inbred Strains; Serotonin Antagonists | 1988 |
Chemical modification of rat cerebral cortex M1 muscarinic receptors: role of histidyl residues in antagonist and agonist binding.
Topics: Animals; Atropine; Benzilates; Binding Sites; Carbachol; Cerebral Cortex; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Oxotremorine; Piperidines; Rats; Receptors, Muscarinic; Synaptosomes | 1988 |
Binding of muscarine receptor antagonists to pig coronary smooth muscle.
Topics: Animals; Atropine; Carbachol; Coronary Vessels; Heart Atria; In Vitro Techniques; Muscle, Smooth, Vascular; Piperazines; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Swine; Tritium | 1988 |
Interaction of himbacine with carbachol at muscarinic receptors of heart and smooth muscle.
Topics: Alkaloids; Animals; Carbachol; Female; Furans; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Naphthalenes; Parasympatholytics; Piperidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stomach | 1987 |
Characterization of the muscarinic receptor subtype in isolated gastric fundic cells of the rabbit.
Topics: Aminopyrine; Animals; Atropine; Carbachol; Gastric Fundus; Kinetics; Male; N-Methylscopolamine; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
Nicotine, cotinine, and anabasine inhibit aromatase in human trophoblast in vitro.
Topics: Anabasine; Androstenedione; Aromatase Inhibitors; Carbachol; Cells, Cultured; Choriocarcinoma; Cotinine; Decamethonium Compounds; Dose-Response Relationship, Drug; Estradiol; Female; Hexamethonium Compounds; Humans; In Vitro Techniques; Kinetics; Microsomes; Nicotine; Piperidines; Placenta; Pregnancy; Pyrrolidinones; Smoking; Succinylcholine; Trophoblasts; Uterine Neoplasms | 1986 |
Reduction of quantal size by vesamicol (AH5183), an inhibitor of vesicular acetylcholine storage.
Topics: Acetylcholine; Animals; Carbachol; In Vitro Techniques; Membrane Potentials; Mice; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Phencyclidine; Piperidines; Receptors, Cholinergic; Synaptic Vesicles | 1986 |
Role of lipids in age-related changes in the properties of muscarinic receptors in cultured rat heart myocytes.
Topics: Acetylcholine; Animals; Animals, Newborn; Benzilates; Carbachol; Cells, Cultured; Guanylyl Imidodiphosphate; Kinetics; Liposomes; Myocardium; Oxotremorine; Piperidines; Rats; Receptors, Muscarinic | 1986 |
Determination of the muscarinic receptor subtype mediating vasodilatation.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atropine; Benzodiazepinones; Carbachol; Dogs; Female; Femoral Artery; Gallamine Triethiodide; In Vitro Techniques; Male; Pancuronium; Parasympatholytics; Phenethylamines; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Vasodilation | 1985 |
A search for selective antagonists at M2 muscarinic receptors.
Topics: Animals; Atrial Function; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Heart Rate; Ileum; Muscle Contraction; Myocardial Contraction; Piperidines; Receptors, Muscarinic; Structure-Activity Relationship | 1985 |
Influence of SKF-525A congeners, strophanthidin and tissue-culture media on desensitization in frog skeletal muscle.
Topics: Animals; Benzilates; Carbachol; Culture Media; Culture Techniques; Diphenylacetic Acids; Electric Stimulation; Kinetics; Membrane Potentials; Microelectrodes; Muscles; Neuromuscular Depolarizing Agents; Oxyphenonium; Piperidines; Proadifen; Rana temporaria; Strophanthidin; Strophanthins | 1974 |
Specific blockade of cardiac muscarinic receptors by pancuronium bromide.
Topics: Acetylcholine; Androstanes; Animals; Carbachol; Guinea Pigs; Heart; Methacholine Compounds; Neuromuscular Nondepolarizing Agents; Parasympatholytics; Piperidines; Receptors, Drug | 1971 |
[Basic substituted tryptamines and tryptophols. 3. Pharmacologic studies on 1- and 2-position of basic substituted derivatives].
Topics: Animals; Carbachol; Ethanol; Guinea Pigs; Histamine; Histamine H1 Antagonists; Ileum; Indoles; Piperidines; Rats; Scopolamine; Stimulation, Chemical; Sympathomimetics; Tryptamines | 1970 |
Studies on the action of some cholinoceptor agonists on the chick biventer cervicis muscle preparation.
Topics: Acetylcholine; Animals; Carbachol; Chickens; Choline; Cyclohexanols; Decamethonium Compounds; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Electric Stimulation; Ganglionic Stimulants; In Vitro Techniques; Muscle Contraction; Neuromuscular Depolarizing Agents; Neuromuscular Junction; Nicotine; Parasympathomimetics; Physostigmine; Piperidines; Quaternary Ammonium Compounds | 1973 |
[Induction and control of spasmo-analgesia].
Topics: Analgesics; Antipyrine; Carbachol; Colic; Dioxoles; Humans; Methylamines; Pain; Parasympatholytics; Pentazocine; Piperidines; Sulfonic Acids; Urinary Bladder Diseases | 1971 |
5,5-diphenyl-2-(2'-piperidinoethyl)-1,3-dioxolane-4-one a new drug with potent spasmolytic activity.
Topics: Acetylcholine; Animals; Asthma; Atropine; Barium; Blood Pressure; Blood Vessels; Carbachol; Cats; Chlorides; Dioxoles; Guinea Pigs; Heart Rate; Histamine; Ileum; Jejunum; Muscle Contraction; Muscles; Papaverine; Parasympatholytics; Piperidines; Rabbits; Respiration; Vagus Nerve | 1970 |
The influence of 1-[3-(1-cyclohexenyl)-3-phenylpropyl]-1-methylpiperidinium bromide (HOE 019) on gastric secretion in the rat.
Topics: Anesthesia; Animals; Atropine; Carbachol; Cyclohexanes; Depression, Chemical; Electric Stimulation; Gastric Acidity Determination; Gastric Juice; Gastric Mucosa; Histamine; Insulin Antagonists; Male; Parasympatholytics; Piperidines; Pylorus; Rats; Secretory Rate; Stimulation, Chemical; Vagus Nerve | 1970 |
The rate of action of atropine.
Topics: Animals; Atropine; Carbachol; Choline; Dibenzylchlorethamine; Guinea Pigs; Heart; Heart Atria; Hexamethonium Compounds; Ileum; In Vitro Techniques; Kinetics; Models, Biological; Perfusion; Physostigmine; Piperidines; Receptors, Drug; Reserpine | 1968 |
Central and peripheral anticholinergic potency of some drugs antagonistic to anticholinesterase poisoning.
Topics: Animals; Antidotes; Atropine; Bradycardia; Carbachol; Central Nervous System; Cholinesterase Inhibitors; Female; Guinea Pigs; Hallucinogens; Heart Rate; Mandelic Acids; Methacholine Compounds; Mice; Parasympatholytics; Peripheral Nerves; Phosphates; Piperidines; Pupil; Quaternary Ammonium Compounds; Rabbits; Scopolamine; Seizures; Trihexyphenidyl | 1968 |
Fatty acid incorporation increases the affinity of muscarinic cholinergic receptors for agonists.
Topics: Animals; Benzilates; Carbachol; Cell Membrane; Cerebral Cortex; Cobalt; Fatty Acids; Guanosine Triphosphate; Medulla Oblongata; Piperidines; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 1984 |
Antagonism of the 5-HT-induced bronchoconstriction in the cat.
Topics: Animals; Bronchi; Carbachol; Cats; Clenbuterol; Cyproheptadine; Female; Hemodynamics; Ketanserin; Male; Piperidines; Pregnancy; Serotonin; Serotonin Antagonists; Theophylline | 1983 |
4-(Diphenylmethyl)-1-[(imino)methyl]piperidines as gastric antisecretory agents.
Topics: Animals; Anti-Ulcer Agents; Binding, Competitive; Carbachol; Female; Gastric Acid; Gastric Emptying; Piperidines; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Structure-Activity Relationship | 1983 |
Vasoactive intestinal polypeptide enhances muscarinic ligand binding in cat submandibular salivary gland.
Topics: Animals; Benzilates; Binding, Competitive; Carbachol; Cats; Gastrointestinal Hormones; Kinetics; Parasympatholytics; Piperidines; Receptors, Cholinergic; Receptors, Muscarinic; Submandibular Gland; Vasoactive Intestinal Peptide | 1982 |
Kinetic studies on muscarinic antagonist-agonist competition.
Topics: Animals; Atropine; Benzilates; Binding, Competitive; Carbachol; Intestine, Small; Kinetics; Male; Muscle, Smooth; Oxotremorine; Parasympatholytics; Piperidines; Rats; Receptors, Cholinergic; Receptors, Muscarinic | 1980 |
5-HT4 receptor antagonist affinities of SB207710, SB205008, and SB203186 in the human colon, rat oesophagus, and guinea-pig ileum peristaltic reflex.
Topics: Animals; Carbachol; Colon; Dioxanes; Esophagus; Female; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indoles; Male; Muscle, Smooth; Peristalsis; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Antagonists | 1995 |
Characterization of the muscarine receptor subtype on sympathetic nerve endings in the rat caudal artery.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Arteries; Atropine; Bis-Trimethylammonium Compounds; Carbachol; Female; In Vitro Techniques; Isoindoles; Male; Muscarinic Antagonists; Muscle, Smooth, Vascular; Nerve Endings; Parasympatholytics; Piperidines; Rats; Rats, Wistar; Receptors, Muscarinic; Sympathetic Nervous System; Tail; Trihexyphenidyl | 1994 |
M2-type muscarinic receptors mediate prejunctional inhibition of norepinephrine release in the human iris-ciliary body.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Carbachol; Child; Ciliary Body; Diamines; Dose-Response Relationship, Drug; Electric Stimulation; Humans; In Vitro Techniques; Iris; Middle Aged; Muscarine; Norepinephrine; Pilocarpine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1994 |
A single transmitter regulates gene expression through two separate mechanisms: cholinergic regulation of phenylethanolamine N-methyltransferase mRNA via nicotinic and muscarinic pathways.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Adrenal Medulla; Animals; Atropine; Binding, Competitive; Calcimycin; Calcium; Carbachol; Cattle; Cells, Cultured; Colforsin; Epinephrine; Gene Expression Regulation, Enzymologic; Hexamethonium; Hexamethonium Compounds; Kinetics; Muscarine; Nicotine; Phenylethanolamine N-Methyltransferase; Piperidines; Quinuclidinyl Benzilate; Receptors, Muscarinic; Receptors, Nicotinic; RNA, Messenger | 1994 |
An immortalised murine hypothalamic neuronal cell, GT1-7, expresses functional histamine H1 receptors.
Topics: Animals; Carbachol; Cell Line, Transformed; Dose-Response Relationship, Drug; Glutamic Acid; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Hypothalamus; Inositol Phosphates; Kinetics; Mice; Neurons; Neuropeptide Y; Piperidines; Pyrimidinones; Ranitidine; Receptors, Histamine H1; Serotonin; Substance P; Tritium | 1994 |
Characterization of muscarinic receptors mediating relaxation and contraction in the rat iris dilator muscle.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Alkaloids; Animals; Arecoline; Bethanechol; Carbachol; Diamines; Dose-Response Relationship, Drug; Furans; Ganglia, Parasympathetic; Ganglionectomy; Iris; Male; Methacholine Chloride; Muscarinic Agonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1995 |
Functional role of proline and tryptophan residues highly conserved among G protein-coupled receptors studied by mutational analysis of the m3 muscarinic receptor.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Blotting, Northern; Carbachol; Cell Line; Codon; GTP-Binding Proteins; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Parasympatholytics; Piperidines; Proline; Protein Conformation; Rats; Receptors, Muscarinic; Recombinant Proteins; Restriction Mapping; RNA; Scopolamine Derivatives; Transfection; Tryptophan | 1993 |
Tachykinins contract the circular muscle of the human esophageal body in vitro via NK2 receptors.
Topics: Adolescent; Adult; Aged; Atropine; Benzamides; Biphenyl Compounds; Carbachol; Dose-Response Relationship, Drug; Esophagus; Glycopeptides; Humans; Isometric Contraction; Middle Aged; Muscle Contraction; Muscle, Smooth; Neprilysin; Neurokinin A; Neurokinin B; Piperidines; Receptors, Tachykinin; Substance P; Tachykinins; Tetrodotoxin | 1993 |
Functional characterization of a muscarinic receptor stimulating gastrin release from rabbit antral G-cells in primary culture.
Topics: Animals; Arecoline; Atropine; Benzodiazepinones; Carbachol; Cell Adhesion; Cell Separation; Cells, Cultured; Gastrins; Immunohistochemistry; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Pyloric Antrum; Rabbits; Receptors, Muscarinic | 1994 |
Different mechanism of tachykinin NK2 receptor blockade by SR 48968 and MEN 10,627 in the guinea-pig isolated gallbladder and colon.
Topics: Amino Acid Sequence; Animals; Benzamides; Binding, Competitive; Carbachol; Colon; Gallbladder; Guinea Pigs; In Vitro Techniques; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Neurokinin A; Peptide Fragments; Peptides, Cyclic; Piperidines; Receptors, Neurokinin-2 | 1994 |
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mulatta; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Quinuclidines | 1994 |
Formation of inositol phosphates mediated by M3 muscarinic receptors in type-1 and type-2 astrocytes from neonatal rat cerebral cortex.
Topics: Animals; Animals, Newborn; Astrocytes; Atropine; Carbachol; Cells, Cultured; Cerebral Cortex; Inositol Phosphates; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Signal Transduction; Tubocurarine | 1994 |
Antimuscarinic action of liriodenine, isolated from Fissistigma glaucescens, in canine tracheal smooth muscle.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Antineoplastic Agents, Phytogenic; Aporphines; Binding, Competitive; Carbachol; Cells, Cultured; Cyclic AMP; Diamines; Dogs; Female; Hydrolysis; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Phosphatidylinositols; Piperidines; Plants, Medicinal; Receptors, Muscarinic; Trachea | 1994 |
Muscarinic M3 receptor-mediated release of gastrin from canine antral G cells in primary culture.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Dogs; Dose-Response Relationship, Drug; Enterochromaffin Cells; Gastrins; Muscarinic Antagonists; Parasympathetic Nervous System; Parasympatholytics; Piperidines; Pirenzepine; Pyloric Antrum; Receptor, Muscarinic M3; Receptors, Muscarinic; Stimulation, Chemical | 1995 |
Characterization of neurotensin-stimulated phosphoinositide hydrolysis in brain regions of long sleep and short sleep mice.
Topics: Animals; Brain; Calcium; Carbachol; Cerebellum; Dose-Response Relationship, Drug; Hippocampus; Histamine H1 Antagonists; Hydrolysis; Inositol; Inositol Phosphates; Kinetics; Membrane Lipids; Mesencephalon; Mice; Mice, Inbred Strains; Neurotensin; Nucleus Accumbens; Organ Specificity; Phosphatidylinositols; Phospholipids; Piperidines; Receptors, Neurotensin; Second Messenger Systems; Sleep | 1993 |
New classes of antimuscarinic agents endowed with selective antispasmodic properties. 1-Arylsulfonyl pyrrolidin-2-ones and 2-thiones, 1-arylsulfonyl piperidin-2-ones and 2-thiones and 1-arylsulfonyl hexahydro-2H-azepin-2-one.
Topics: Animals; Arecoline; Atropine; Azepines; Butylscopolammonium Bromide; Carbachol; Gastric Acid; Gastrointestinal Motility; Guinea Pigs; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Parasympatholytics; Piperidines; Pupil; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Scopolamine Derivatives; Sulfones | 1994 |
Cholinergic dilatation and constriction of feline cerebral blood vessels are mediated by stimulation of phosphoinositide metabolism via two different muscarinic receptor subtypes.
Topics: Animals; Carbachol; Cats; Cerebral Arteries; Cerebrovascular Circulation; Dose-Response Relationship, Drug; Endothelium, Vascular; In Vitro Techniques; Inositol Phosphates; Muscarinic Antagonists; Muscle, Smooth, Vascular; Parasympatholytics; Phosphatidylinositols; Pia Mater; Piperidines; Pirenzepine; Receptors, Muscarinic; Vasoconstriction; Vasodilation | 1994 |
In vitro pharmacologic characterization of a cholinergic receptor on outer hair cells.
Topics: Acetylcholine; Alkaloids; Animals; Atropine; Azocines; Bungarotoxins; Carbachol; Choline; Cholinergic Antagonists; Curare; Dimethylphenylpiperazinium Iodide; Guinea Pigs; Hair Cells, Auditory, Outer; In Vitro Techniques; Membrane Potentials; Nicotine; Piperidines; Pirenzepine; Quinolizines; Receptors, Cholinergic; Strychnine; Trimethaphan | 1994 |
Insertion mutagenesis as a tool to predict the secondary structure of a muscarinic receptor domain determining specificity of G-protein coupling.
Topics: Acetylcholine; Amino Acid Sequence; Animals; Binding Sites; Carbachol; Cell Line; Chlorocebus aethiops; GTP-Binding Proteins; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Insertional; N-Methylscopolamine; Phosphatidylinositols; Piperidines; Protein Structure, Secondary; Rats; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Transfection | 1994 |
Selective blockade of different brain stem muscarinic receptor subtypes: effects on the sleep-wake cycle.
Topics: Animals; Brain Stem; Carbachol; Diamines; Electroencephalography; Male; Microinjections; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Polysomnography; Rats; Reticular Formation; Sleep; Wakefulness | 1994 |
Tachykinin receptors in the rat isolated uterus.
Topics: Animals; Anti-Bacterial Agents; Benzamides; Carbachol; Estradiol; Female; Glycopeptides; Kinetics; Neurokinin A; Neurokinin-1 Receptor Antagonists; Peptide Fragments; Peptides; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Neurokinin-1; Receptors, Neurokinin-2; Uterus | 1993 |
Agonist-induced down-regulation and antagonist-induced up-regulation of m2- and m3-muscarinic acetylcholine receptor mRNA and protein in cultured cerebellar granule cells.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Cerebellum; Down-Regulation; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; RNA, Messenger; Up-Regulation | 1993 |
Coexpression studies with mutant muscarinic/adrenergic receptors provide evidence for intermolecular "cross-talk" between G-protein-linked receptors.
Topics: Acetylcholine; Animals; Carbachol; Cell Line; GTP-Binding Proteins; Kinetics; Models, Structural; N-Methylscopolamine; Parasympatholytics; Phosphatidylinositols; Piperidines; Protein Structure, Secondary; Rats; Receptors, Adrenergic, alpha; Receptors, Muscarinic; Recombinant Fusion Proteins; Scopolamine Derivatives; Signal Transduction; Transfection; Yohimbine | 1993 |
Differences between rat dorsal and ventral hippocampus in muscarinic receptor agonist binding and interaction with phospholipase C.
Topics: Alkaloids; Animals; Carbachol; Furans; Guanylyl Imidodiphosphate; Hippocampus; Male; Membranes; Mitochondria; N-Methylscopolamine; Naphthalenes; Oxotremorine; Parasympatholytics; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes; Type C Phospholipases | 1993 |
Differential effects of alkylating agents on the multiple muscarinic receptor subtypes linked to activation of phospholipase C by carbachol in rat brain cortical membranes.
Topics: Alkylating Agents; Animals; Carbachol; Cerebral Cortex; Enzyme Activation; In Vitro Techniques; Male; Mustard Compounds; Piperidines; Pirenzepine; Propylbenzilylcholine Mustard; Quinolines; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Type C Phospholipases | 1993 |
Muscarinic receptor regulation and 2nd messenger responses in rat neocortex cultures.
Topics: Animals; Binding, Competitive; Carbachol; Cells, Cultured; Cerebral Cortex; Down-Regulation; Oxotremorine; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Second Messenger Systems | 1993 |
Subtype of muscarinic receptors mediating relaxation and contraction in the rat iris dilator smooth muscle.
Topics: Alkaloids; Animals; Atropine; Carbachol; Furans; In Vitro Techniques; Iris; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic | 1993 |
H3-receptor activation inhibits cholinergic stimulation of acid secretion in isolated rabbit fundic glands.
Topics: Animals; Carbachol; Cholinergic Antagonists; Gastric Acid; Gastric Fundus; Gastric Mucosa; Histamine Agonists; Histamine Antagonists; In Vitro Techniques; Methylhistamines; Muscarinic Antagonists; N-Methylscopolamine; Piperidines; Rabbits; Ranitidine; Receptors, Histamine H3; Receptors, Muscarinic; Scopolamine Derivatives | 1995 |
Muscarinic depression of excitatory synaptic transmission mediated by the presynaptic M3 receptors in the rat neostriatum.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Carbachol; Depression, Chemical; Electric Stimulation; Evoked Potentials; In Vitro Techniques; N-Methylaspartate; Neostriatum; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Presynaptic; Synaptic Transmission | 1995 |
Characterization of muscarinic receptors mediating contractions of circular and longitudinal muscle of human isolated colon.
Topics: Alkaloids; Atropine; Carbachol; Carcinoma; Colon; Colonic Neoplasms; Dose-Response Relationship, Drug; Furans; Humans; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperidines; Pirenzepine | 1995 |
In vivo and in vitro effects of muscarinic receptor antagonists on contractions and release of [3H]acetylcholine in the rabbit urinary bladder.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Female; Gallamine Triethiodide; Muscarinic Antagonists; Muscle Contraction; Parasympatholytics; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Tritium; Urinary Bladder | 1995 |
S-(-)-ET 126: a potent and selective M1 antagonist in vitro and in vivo.
Topics: Acetylcholine; Animals; Atrial Function, Left; Carbachol; Dose-Response Relationship, Drug; Ileum; In Vitro Techniques; Male; Mice; Muscarinic Antagonists; Phenylacetates; Piperidines; Pirenzepine; Rabbits; Rats; Vas Deferens | 1996 |
Binding of the labelled muscarinic toxin 125I-MT1 to rat brain muscarinic M1 receptors.
Topics: Alkaloids; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Elapid Venoms; Furans; Gallamine Triethiodide; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; Naphthalenes; Oxotremorine; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Protein Binding; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Synaptic Membranes; Tubocurarine | 1996 |
Carbachol stimulates inositol phosphate formation in rat thalamus slices through muscarinic M3-receptor activation.
Topics: Animals; Binding, Competitive; Carbachol; Dose-Response Relationship, Drug; Inositol Phosphates; Male; Muscarinic Agonists; Muscarinic Antagonists; Organ Culture Techniques; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Thalamus; Tritium | 1996 |
Muscarinic receptor heterogeneity in neonatal rat ventricular myocytes in culture.
Topics: Animals; Animals, Newborn; Carbachol; Cells, Cultured; Cyclic AMP; GTP-Binding Proteins; Heart Rate; Inositol Phosphates; Muscarinic Agonists; Muscarinic Antagonists; Myocardium; Pertussis Toxin; Piperidines; Rats; Receptor, Muscarinic M2; Receptors, Muscarinic; Signal Transduction; Stimulation, Chemical; Virulence Factors, Bordetella | 1996 |
Muscarinic receptor subtypes in the submandibular gland and the urinary bladder of the rabbit: in vivo and in vitro functional comparisons of receptor antagonists.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscarinic Antagonists; Piperidines; Pirenzepine; Rabbits; Receptors, Muscarinic; Submandibular Gland; Urinary Bladder | 1995 |
Effect of cholinergic agonists on gastrin release from primary cultures of human antral G cells.
Topics: Adult; Antibodies; Bombesin; Calcium; Carbachol; Cells, Cultured; Female; Gastrins; Humans; Male; Methacholine Chloride; Middle Aged; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pyloric Antrum; Somatostatin | 1997 |
Abnormalities in the contractile properties of colonic smooth muscle in idiopathic slow transit constipation.
Topics: Adolescent; Adult; Aged; Carbachol; Cisapride; Colorectal Neoplasms; Constipation; Female; Gastrointestinal Transit; Humans; Isometric Contraction; Middle Aged; Muscle, Smooth; Piperidines | 1997 |
Carbachol induces inward current in rat neostriatal neurons through a G-protein-coupled mechanism.
Topics: Animals; Carbachol; Cyclic AMP-Dependent Protein Kinases; GTP-Binding Proteins; Male; Muscarinic Agonists; Neostriatum; Neurons; Patch-Clamp Techniques; Piperidines; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 1997 |
Circulating antibodies against rat parotid gland M3 muscarinic receptors in primary Sjögren's syndrome.
Topics: Adolescent; Adrenergic beta-Agonists; Adult; Animals; Antibodies, Blocking; Atropine; Carbachol; Carbamates; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Female; Humans; Immunoglobulin G; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Parotid Gland; Phenylcarbamates; Phosphatidylinositols; Piperidines; Pirenzepine; Protease Inhibitors; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Sjogren's Syndrome | 1996 |
Critical role for M3 muscarinic receptors in paradoxical sleep generation in the cat.
Topics: Animals; Carbachol; Cats; Muscarinic Antagonists; Piperidines; Receptors, Muscarinic; Sleep | 1997 |
Muscarinic acetylcholine receptors on rat thymocytes: their possible involvement in DNA fragmentation.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Atropine; Binding, Competitive; Carbachol; DNA Fragmentation; Electrophoresis, Agar Gel; Hydrocortisone; Injections, Subcutaneous; Isotope Labeling; Male; Muscarinic Agonists; Muscarinic Antagonists; Nucleosomes; Oxotremorine; Piperidines; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Thymus Gland | 1997 |
Inhibition of M3 muscarinic acetylcholine receptor-mediated Ca2+ influx and intracellular Ca2+ mobilization in neuroblastoma cells by the Ca2+/calmodulin-dependent protein kinase inhibitor 1-[N,O-bis(5-isoquinolinesulfonyl)-N-methyl-L-trosyl]-4-phenylpipe
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Enzyme Inhibitors; Humans; Neuroblastoma; Piperidines; Receptor, Muscarinic M3; Receptors, Muscarinic; Signal Transduction; Tumor Cells, Cultured | 1997 |
Cholinergic modulation of electrogenic ion transport in different regions of the rat small intestine.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Analysis of Variance; Animals; Atropine; Bethanechol; Carbachol; Chlorides; Diamines; Duodenum; Ileum; Intestinal Mucosa; Ion Transport; Jejunum; Male; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic; Structure-Activity Relationship; Tetrodotoxin | 1997 |
M3 muscarinic receptor-mediated enhancement of NMDA-evoked adenosine release in rat cortical slices in vitro.
Topics: Adenosine; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Atropine; Carbachol; Cerebral Cortex; Diamines; Drug Synergism; In Vitro Techniques; Kinetics; Magnesium; Male; Muscarinic Agonists; Muscarinic Antagonists; N-Methylaspartate; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptors, Muscarinic | 1997 |
Carbachol-induced inositol phosphate formation in rat striatum is mediated by both M1 and M3 muscarinic receptors.
Topics: Animals; Carbachol; Corpus Striatum; Drug Evaluation, Preclinical; In Vitro Techniques; Inositol Phosphates; Muscarinic Antagonists; Piperidines; Pirenzepine; Rats; Rats, Wistar | 1997 |
Muscarinic receptor subtypes controlling the cationic current in guinea-pig ileal smooth muscle.
Topics: Animals; Carbachol; Dioxoles; Dose-Response Relationship, Drug; Electric Conductivity; Guinea Pigs; Ileum; In Vitro Techniques; Ion Channels; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Patch-Clamp Techniques; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic | 1997 |
Pirmenol inhibits muscarinic acetylcholine receptor-operated K+ current in the guinea pig heart.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Carbachol; Disopyramide; Electric Stimulation; Guinea Pigs; Heart; Patch-Clamp Techniques; Piperidines; Potassium Channels; Receptors, Muscarinic | 1997 |
Two opposite signal transducing mechanisms regulate a G-protein-coupled guanylyl cyclase.
Topics: Animals; Carbachol; Cattle; Cell Membrane; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanylate Cyclase; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth; Pertussis Toxin; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Signal Transduction; Trachea; Virulence Factors, Bordetella | 1998 |
Muscarinic facilitation of GABA release in substantia gelatinosa of the rat spinal dorsal horn.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Carbachol; Diamines; Evoked Potentials; gamma-Aminobutyric Acid; In Vitro Techniques; Interneurons; Muscarinic Agonists; Neostigmine; Neurons; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Substantia Gelatinosa; Synaptic Transmission; Tetrodotoxin | 1998 |
Characterization of muscarinic receptors mediating the contraction of the urinary detrusor muscle in cynomolgus monkeys and guinea pigs.
Topics: Animals; Carbachol; Diamines; Female; Guinea Pigs; Macaca fascicularis; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptors, Muscarinic; Urinary Bladder | 1998 |
M2 and M3 muscarinic receptors couple, respectively, with activation of nonselective cationic channels and potassium channels in intestinal smooth muscle cells.
Topics: Animals; Atropine; Calcium; Carbachol; Guinea Pigs; Male; Muscarinic Agonists; Muscle, Smooth; Piperidines; Pirenzepine; Potassium Channels; Receptors, Muscarinic | 1998 |
Pharmacological and molecular characterization of muscarinic receptors in cat esophageal smooth muscle.
Topics: Amino Acid Sequence; Animals; Base Sequence; Carbachol; Cats; Dioxoles; Electric Stimulation; Esophagus; Female; Male; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth; Piperidines; Polymerase Chain Reaction; Receptors, Muscarinic; RNA, Messenger | 1998 |
Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Behavior, Animal; Carbachol; Cataplexy; Cholinergic Fibers; Dogs; Feeding Behavior; Female; GABA Agonists; Gallamine Triethiodide; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Muscimol; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Piperidines; Pirenzepine; Prosencephalon | 1998 |
Muscarinic inhibition of substance P induced ion secretion in piglet jejunum.
Topics: Animals; Atropine; Carbachol; Cholinergic Antagonists; Dose-Response Relationship, Drug; Drug Interactions; Gallamine Triethiodide; Histamine; Ion Transport; Jejunum; Mecamylamine; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Substance P; Swine; Time Factors | 1998 |
Pharmacological and functional characterization of muscarinic receptors in the frog pars intermedia.
Topics: Acetylcholine; alpha-MSH; Animals; Calcium; Carbachol; Cyclic AMP; Enzyme Inhibitors; Inositol Phosphates; Male; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Pertussis Toxin; Piperidines; Pituitary Gland; Protein-Tyrosine Kinases; Rana ridibunda; Receptors, Muscarinic; Signal Transduction; Virulence Factors, Bordetella | 1998 |
Calcium signaling in cultured human and rat duodenal enterocytes.
Topics: Animals; Calcium; Carbachol; Cell Adhesion; Cells, Cultured; Dose-Response Relationship, Drug; Duodenum; Extracellular Matrix; Fluorescent Dyes; Fura-2; Humans; Intestinal Mucosa; Male; Parasympatholytics; Piperidines; Rats; Rats, Inbred Lew; Signal Transduction; Sincalide; Vacuoles | 1998 |
The actions of the cannabinoid receptor antagonist, SR 141716A, in the rat isolated mesenteric artery.
Topics: Animals; Benzimidazoles; Calcium; Cannabinoids; Carbachol; Cromakalim; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; In Vitro Techniques; Male; Mesenteric Arteries; Methoxamine; Muscle Relaxation; Muscle, Smooth, Vascular; Penicillamine; Piperidines; Potassium Channels; Pyrazoles; Rats; Rats, Wistar; Rimonabant | 1998 |
In vitro functional evidence of neuronal cannabinoid CB1 receptors in human ileum.
Topics: Adult; Aged; Aged, 80 and over; Benzoxazines; Calcium Channel Blockers; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Female; Humans; Ileum; In Vitro Techniques; Male; Middle Aged; Morpholines; Muscle Contraction; Muscle, Smooth; Naphthalenes; Neurons; Piperidines; Pyrazoles; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Tetrodotoxin | 1998 |
Characterization of cannabinoid receptors coupled to vasorelaxation by endothelium-derived hyperpolarizing factor.
Topics: Animals; Benzofurans; Biological Factors; Carbachol; Cyclooxygenase Inhibitors; Endothelium, Vascular; In Vitro Techniques; Indoles; Male; Muscarinic Agonists; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant; Vasodilation | 1999 |
Contractile and phosphatidylinositol responses of rat trachea to anticholinesterase drugs.
Topics: Animals; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Dimethylphenylpiperazinium Iodide; Edrophonium; Glucose; Inositol; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neostigmine; Neuromuscular Blocking Agents; Nicotinic Agonists; Organ Preservation Solutions; Phosphatidylinositols; Piperidines; Pyridostigmine Bromide; Radiopharmaceuticals; Rats; Rats, Wistar; Tetrodotoxin; Trachea; Tritium; Tromethamine | 1998 |
M2 receptors in genito-urinary smooth muscle pathology.
Topics: Animals; Binding Sites; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Hypertrophy; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Denervation; Muscle, Smooth; Organ Size; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Spinal Cord Injuries; Urinary Bladder; Urinary Bladder, Neurogenic | 1999 |
Activation of muscarinic M3-like receptors and beta-adrenoceptors, but not M2-like muscarinic receptors or alpha-adrenoceptors, directly modulates corticostriatal neurotransmission in vitro.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; 6-Cyano-7-nitroquinoxaline-2,3-dione; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic Fibers; Animals; Carbachol; Cerebral Cortex; Cholinergic Fibers; Corpus Striatum; Diamines; Excitatory Amino Acid Agonists; Excitatory Postsynaptic Potentials; Glutamic Acid; Imidazoles; Isoproterenol; Male; Medetomidine; Mice; Mice, Inbred DBA; Muscarinic Agonists; Muscarinic Antagonists; Phenylephrine; Piperidines; Pirenzepine; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Receptors, AMPA; Receptors, Muscarinic; Scopolamine; Synaptic Transmission | 1999 |
A comparative study in rats of the in vitro and in vivo pharmacology of the acetylcholinesterase inhibitors tacrine, donepezil and NXX-066.
Topics: Acetylcholinesterase; Animals; Butyrylcholinesterase; Carbachol; Cholinesterase Inhibitors; Donepezil; Drug Evaluation, Preclinical; Humans; Indans; Indoles; Injections, Intraperitoneal; Isoquinolines; Logistic Models; Male; Physostigmine; Piperidines; Rats; Structure-Activity Relationship; Tacrine; Tumor Cells, Cultured | 1999 |
Function of M3 muscarinic receptors in the rat urinary bladder following partial outlet obstruction.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Urinary Bladder Neck Obstruction | 1999 |
Effect of continuous administration of a cholinergic agonist on [3H]4-DAMP binding and m3 mRNA expression in cultured human ciliary muscle cells.
Topics: Carbachol; Cells, Cultured; Cholinergic Agonists; Ciliary Body; Humans; Muscarinic Antagonists; Piperidines; Receptor, Muscarinic M3; Receptors, Muscarinic; RNA, Messenger | 1999 |
Presynaptic muscarinic (M3) receptors reduce excitatory transmission in dopamine neurons of the rat mesencephalon.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Atropine; Carbachol; Diamines; Dicyclomine; Dopamine; Electric Stimulation; Excitatory Postsynaptic Potentials; Mesencephalon; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Parasympatholytics; Physostigmine; Piperidines; Pirenzepine; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reaction Time; Receptor, Muscarinic M3; Receptors, Muscarinic; Synaptic Transmission; Tetrodotoxin | 1999 |
Influence of fluoxetine and litoxetine on 5-HT4 receptor-mediated relaxation in the rat isolated oesophagus.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Drug Interactions; Esophagus; Fenclonine; Fluoxetine; In Vitro Techniques; Indoles; Male; Muscle Relaxation; Muscle, Smooth; Piperidines; Rats; Rats, Wistar; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin Antagonists; Sulfonamides | 1999 |
Effect of cholinergic drugs on the concentration of intracellular free calcium of rat pituitary intermediate lobe cells.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Age Factors; Animals; Atropine; Calcium; Carbachol; Cells, Cultured; Cholinergic Agonists; Cytosol; Female; Male; Melanocytes; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Piperidines; Pirenzepine; Pituitary Gland; Rats; Rats, Wistar; Vasodilator Agents | 1999 |
Muscarinic receptor heterogeneity in follicle-enclosed Xenopus oocytes.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Gene Expression; Membrane Potentials; Muscarinic Antagonists; Oocytes; Ovarian Follicle; Oxotremorine; Patch-Clamp Techniques; Piperidines; Pirenzepine; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Tropicamide; Xenopus laevis | 1999 |
Acetylcholine modulates respiratory pattern: effects mediated by M3-like receptors in preBötzinger complex inspiratory neurons.
Topics: Acetylcholine; Animals; Animals, Newborn; Carbachol; Electrophysiology; In Vitro Techniques; Membrane Potentials; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Neurons; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Receptors, Muscarinic; Respiratory Mechanics; Synapses; Tetrodotoxin | 2000 |
Facilitation of cholinergic transmission by substance P methyl ester in the mouse hippocampal slice preparation.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetylcholine; Action Potentials; Animals; Atropine; Bicuculline; Carbachol; Cholinergic Agonists; Drug Synergism; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Hippocampus; Male; Membrane Potentials; Mice; Patch-Clamp Techniques; Piperidines; Pyramidal Cells; Quinuclidines; Receptors, N-Methyl-D-Aspartate; Receptors, Neurokinin-1; Substance P; Tetrodotoxin; Valine | 2000 |
Effects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Atropine; Benzoxazines; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Electrophysiology; Humans; In Vitro Techniques; Macaca fascicularis; Male; Mice; Morpholines; Muscle Contraction; Naphthalenes; Piperidines; Pyrazoles; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Receptors, Muscarinic; Rimonabant; Species Specificity; Swine; Urinary Bladder | 2000 |
Cholinergic facilitation of neurotransmission to the smooth muscle of the guinea-pig prostate gland.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Electric Stimulation; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Prostate; Receptor, Muscarinic M1; Receptors, Muscarinic; Synaptic Transmission | 2000 |
Cellular signaling by the potent bronchoconstrictor endothelin-1 in airway smooth muscle.
Topics: Adenylyl Cyclase Inhibitors; Animals; Azepines; Carbachol; Cholinergic Agonists; Endothelin-1; Female; Inositol Phosphates; Male; Muscle, Smooth; Oligopeptides; Piperidines; Signal Transduction; Swine; Trachea | 2000 |
Nitric oxide-induced cGMP accumulation in the mouse bladder is not related to smooth muscle relaxation.
Topics: Animals; Arginine; Carbachol; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; In Vitro Techniques; Mice; Mice, Inbred BALB C; Molsidomine; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Donors; Nitric Oxide Synthase; Nitroarginine; Nitroprusside; Phosphodiesterase Inhibitors; Piperazines; Piperidines; Purines; Quinazolines; Sildenafil Citrate; Sulfones; Urethra; Urinary Bladder | 2000 |
Carbachol and acetylcholine delay the early postdenervation depolarization of muscle fibres through M1-cholinergic receptors.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Carbachol; Culture Techniques; Diaphragm; Male; Membrane Potentials; Muscarinic Agonists; Muscarinic Antagonists; Muscle Denervation; Muscle Fibers, Skeletal; Oxotremorine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic | 2000 |
Influence of gender and the oestrous cycle on in vitro contractile responses of the rat urinary bladder to cholinergic stimulation.
Topics: Animals; Carbachol; Cholinergic Agonists; Diamines; Electric Stimulation; Estrus; Female; Male; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Sex Characteristics; Time Factors; Urinary Bladder; Uterine Contraction | 2000 |
Neural pathways regulating Brunner's gland secretion in guinea pig duodenum in vitro.
Topics: Animals; Brunner Glands; Capsaicin; Carbachol; Choline O-Acetyltransferase; Cholinergic Agonists; Cholinergic Fibers; Dimethylphenylpiperazinium Iodide; Duodenum; Electric Stimulation; Female; Ganglia, Sympathetic; Guanethidine; Guinea Pigs; Hexamethonium; In Vitro Techniques; Male; Muscarinic Antagonists; Neural Pathways; Neurotransmitter Agents; Nicotinic Agonists; Nicotinic Antagonists; Piperidines; Submucous Plexus; Substance P; Sympatholytics; Tetrodotoxin; Vagotomy; Vagus Nerve | 2000 |
The role of M(2)-muscarinic receptors in mediating contraction of the pig urinary bladder in vitro.
Topics: Animals; Benzofurans; Binding, Competitive; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Membranes; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pyrrolidines; Quinuclidinyl Benzilate; Radioligand Assay; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Tritium; Urinary Bladder | 2000 |
A dose-response study of anticholinesterase drugs on contractile and phosphatidylinositol responses of rat trachea.
Topics: Animals; Carbachol; Cholinergic Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Edrophonium; In Vitro Techniques; Inositol Phosphates; Isometric Contraction; Male; Muscarinic Antagonists; Muscle, Smooth; Neostigmine; Phosphatidylinositols; Piperidines; Pyridostigmine Bromide; Rats; Rats, Wistar; Stimulation, Chemical; Trachea | 2001 |
M3 muscarinic receptors but not M2 mediate contraction of the porcine detrusor muscle in vitro.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Swine; Urinary Bladder | 2000 |
Possible mechanisms of diarrheal side effects associated with the use of a novel chemotherapeutic agent, flavopiridol.
Topics: Antineoplastic Agents; Carbachol; Chloride Channels; Chlorides; Cholinergic Agonists; Colforsin; Colon; Cyclic AMP; Cyclin-Dependent Kinases; Diarrhea; Epidermal Growth Factor; Flavonoids; Humans; In Vitro Techniques; Intestinal Mucosa; Piperidines | 2001 |
Functional characterization of rat submaxillary gland muscarinic receptors using microphysiometry.
Topics: Alkaloids; Animals; Atropine; Benzhydryl Compounds; Benzodiazepinones; Binding, Competitive; Biosensing Techniques; Carbachol; Cholinergic Agonists; Cresols; Diamines; Dose-Response Relationship, Drug; Furans; Male; Mandelic Acids; Muscarinic Antagonists; Naphthalenes; Phenethylamines; Phenylpropanolamine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Submandibular Gland; Tolterodine Tartrate | 2001 |
The antinociceptive and sedative effects of carbachol and oxycodone administered into brainstem pontine reticular formation and spinal subarachnoid space in rats.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Animals; Atropine; Behavior, Animal; Carbachol; Cholinergic Agonists; Conscious Sedation; Diamines; Injections, Spinal; Male; Microinjections; Motor Activity; Muscarinic Antagonists; Pain Threshold; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Reticular Formation; Subarachnoid Space | 2001 |
Effect of M2 and M3 muscarinic receptors on airway responsiveness to carbachol in bronchial-hypersensitive (BHS) and bronchial-hyposensitive (BHR) guinea pigs.
Topics: Animals; Bronchial Hyperreactivity; Carbachol; Diamines; Gene Expression; Guinea Pigs; Lung; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Trachea | 2001 |
Effects of cholinergic agents on the vasopressin-mediated water transport in the isolated toad bladder.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arginine Vasopressin; Atropine; Biological Transport; Bufo marinus; Calcium; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Cholinergic Antagonists; In Vitro Techniques; Isotonic Solutions; Lanthanum; Osmolar Concentration; Piperidines; Pirenzepine; Urinary Bladder; Vasoconstrictor Agents; Water | 2001 |
The in vitro pharmacological profile of prucalopride, a novel enterokinetic compound.
Topics: Acetylcholine; Animals; Benzofurans; Binding, Competitive; Carbachol; Cell Line; CHO Cells; Colon; Cricetinae; Dioxanes; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Esophagus; Female; Gallbladder; Gastrointestinal Agents; Granisetron; Guinea Pigs; Humans; Ileum; In Vitro Techniques; Indoles; Indomethacin; Male; Motilin; Muscle Contraction; Piperidines; Rabbits; Rats; Rats, Wistar; Receptors, Cholecystokinin; Receptors, Dopamine D2; Receptors, Dopamine D4; Receptors, Gastrointestinal Hormone; Receptors, Neuropeptide; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sincalide; Stomach; Sulfonamides; Vasodilator Agents | 2001 |
Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Dioxolanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pilocarpine; Piperidines; Receptors, Muscarinic; Urinary Bladder | 2001 |
Muscarinic receptors control K+ secretion in inner ear strial marginal cells.
Topics: Adrenergic beta-Agonists; Animals; Atropine; Calcium; Carbachol; Cholinergic Agonists; Cloning, Molecular; Cyclic AMP; Diamines; Dose-Response Relationship, Drug; Gerbillinae; Isoproterenol; Muscarinic Antagonists; Parasympatholytics; Piperidines; Pirenzepine; Potassium; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Stria Vascularis | 2001 |
On the functional role of muscarinic M2 receptors in cholinergic and purinergic responses in the rat urinary bladder.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Carbachol; Diamines; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Piperidines; Pirenzepine; Purinergic Agonists; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptors, Muscarinic; Receptors, Purinergic; Theophylline; Urinary Bladder | 2001 |
Cyclohexylmethylpiperidinyltriphenylpropioamide: a selective muscarinic M(3) antagonist discriminating against the other receptor subtypes.
Topics: Acetylcholine; Animals; Bradycardia; Bronchoconstriction; Carbachol; CHO Cells; Cholinergic Agents; Combinatorial Chemistry Techniques; Cricetinae; Dipeptides; Heart Atria; Humans; In Vitro Techniques; Muscarinic Antagonists; Piperidines; Rats; Receptor, Muscarinic M3; Receptors, Muscarinic; Structure-Activity Relationship | 2002 |
Activation of nitric oxide synthase through muscarinic receptors in rat parotid gland.
Topics: Amylases; Animals; Atropine; Binding, Competitive; Carbachol; Cell Membrane; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Parotid Gland; Piperidines; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Specific Pathogen-Free Organisms | 2002 |
Two classes of endothelin receptors mediating contraction in esophageal muscularis mucosae.
Topics: Animals; Atropine; Autoradiography; Azepines; Binding, Competitive; Carbachol; Cell Membrane; Cells, Cultured; Endothelin Receptor Antagonists; Endothelins; Esophagus; Guinea Pigs; In Vitro Techniques; Indoles; Male; Mucous Membrane; Muscle Contraction; Oligopeptides; Piperidines; Protein Binding; Receptors, Endothelin; Tetrodotoxin; Viper Venoms | 2002 |
Sensitization of enteric reflexes in the rat colon in vitro.
Topics: Animals; Area Under Curve; Carbachol; Cholinergic Agonists; Colon; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Gastrointestinal Motility; Granisetron; Hexamethonium; In Vitro Techniques; Indomethacin; Male; Muscle Contraction; Neurons, Afferent; Nicotinic Antagonists; Piperidines; Quinuclidines; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Receptors, Tachykinin; Serotonin Antagonists; Time Factors | 2002 |
Interaction between muscarinic receptor subtype signal transduction pathways mediating bladder contraction.
Topics: Animals; Carbachol; Cholinergic Agents; Denervation; Female; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Second Messenger Systems; Signal Transduction; Urinary Bladder; Urinary Incontinence | 2002 |
Activation of muscarinic acetylcholine receptors enhances the release of endogenous cannabinoids in the hippocampus.
Topics: Animals; Calcium; Cannabinoid Receptor Modulators; Cannabinoids; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Evoked Potentials; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Interneurons; Male; Mice; Mice, Knockout; Neural Inhibition; Patch-Clamp Techniques; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptors, Cannabinoid; Receptors, Drug; Receptors, Metabotropic Glutamate; Receptors, Muscarinic | 2002 |
Cholinergic mechanism in the lateral septal area is involved in the stress-induced blood pressure increase in rats.
Topics: Animals; Blood Pressure; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Epinephrine; GABA Agonists; Injections, Intraventricular; Male; Muscarinic Antagonists; Muscimol; Norepinephrine; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Restraint, Physical; Septal Nuclei; Stress, Physiological | 2003 |
New benzimidazole derivatives: selective and orally active 5-HT3 receptor antagonists.
Topics: 5-Hydroxytryptophan; Administration, Oral; Animals; Aza Compounds; Behavior, Animal; Benzimidazoles; Carbachol; Diarrhea; Dose-Response Relationship, Drug; Gastric Emptying; Gastrointestinal Motility; In Vitro Techniques; Injections, Intraperitoneal; Injections, Intravenous; Male; Mice; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Ondansetron; Piperidines; Propane; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Reflex; Serotonin; Serotonin Antagonists | 2003 |
Five subtypes of muscarinic receptors are expressed in gastric smooth muscles of guinea pig.
Topics: Animals; Base Sequence; Carbachol; Cations; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Gastric Mucosa; Guinea Pigs; Ion Channels; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Receptors, Muscarinic; Stomach | 2003 |
Activation of mitogen-activated protein kinase by cholinergic agonists and EGF in human compared with rat cultured conjunctival goblet cells.
Topics: Adult; Aged; Aged, 80 and over; Animals; Blotting, Western; Carbachol; Cells, Cultured; Cholinergic Agonists; Conjunctiva; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Goblet Cells; Humans; Male; Middle Aged; Mitogen-Activated Protein Kinases; Muscarinic Antagonists; Piperidines; Quinazolines; Rats; Rats, Sprague-Dawley; Time Factors; Tyrphostins | 2003 |
Castration decreases amylase release associated with muscarinic acetylcholine receptor downregulation in rat parotid gland.
Topics: Amylases; Animals; Binding, Competitive; Carbachol; Cholinergic Agonists; Down-Regulation; Inositol Phosphates; Male; Orchiectomy; Parotid Gland; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Muscarinic | 2003 |
Nuclear factor kappaB activation by muscarinic receptors in astroglial cells: effect of ethanol.
Topics: Astrocytes; Astrocytoma; Atropine; Blotting, Western; Carbachol; Cell Line; Cellular Structures; Central Nervous System Depressants; Chelating Agents; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Ethanol; Gallamine Triethiodide; Humans; Muscarinic Antagonists; NF-kappa B; Nicotinic Antagonists; Pertussis Toxin; Piperidines; Receptors, Muscarinic; Thymidine; Time Factors; Tritium | 2003 |
Projections from the caudal part to the rostral part of the lateral septal area mediate blood pressure increase.
Topics: Animals; Blood Pressure; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Fluorescent Dyes; GABA Agonists; Hypertension; Male; Microinjections; Muscarinic Antagonists; Muscimol; Neural Pathways; Neurons; Piperidines; Proto-Oncogene Proteins c-fos; Rats; Rats, Wistar; Reaction Time; Septum of Brain; Stress, Physiological | 2003 |
Comparison of the effects of drugs on nitrogen narcosis and oxygen toxicity in rats.
Topics: Animals; Bemegride; Carbachol; Epinephrine; Glutethimide; Hyperoxia; Inert Gas Narcosis; Methamphetamine; Nitrogen; Oxygen; Pentylenetetrazole; Phenacetin; Physostigmine; Piperidines; Rats; Scopolamine | 1962 |
Metoclopramide causes airway smooth muscle relaxation through inhibition of muscarinic M3 receptor in the rat trachea.
Topics: Animals; Antiemetics; Carbachol; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Male; Metoclopramide; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Phosphatidylinositols; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptor, Muscarinic M3; Trachea | 2004 |
Colonic smooth muscle responses in patients with diverticular disease of the colon: effect of the NK2 receptor antagonist SR48968.
Topics: Aged; Aged, 80 and over; Anesthetics, Local; Atropine; Benzamides; Carbachol; Case-Control Studies; Cholinergic Agonists; Colon, Sigmoid; Colonic Neoplasms; Diverticulitis, Colonic; Electric Stimulation; Female; Humans; In Vitro Techniques; Isometric Contraction; Male; Middle Aged; Muscle, Smooth; Parasympatholytics; Piperidines; Receptors, Neurokinin-2; Stress, Mechanical; Tetrodotoxin | 2004 |
Activation of muscarinic acetylcholine receptors elicits pigment granule dispersion in retinal pigment epithelium isolated from bluegill.
Topics: Adenylyl Cyclase Inhibitors; Animals; Arecoline; Atropine; Carbachol; Colforsin; Cyclic AMP; Cytoplasmic Granules; Light; Muscarinic Agonists; Muscarinic Antagonists; Perciformes; Pigment Epithelium of Eye; Piperidines; Pirenzepine; Quaternary Ammonium Compounds; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Retinal Pigments; Second Messenger Systems; Tropicamide | 2004 |
Acetylcholinesterase inhibitors increase ADAM10 activity by promoting its trafficking in neuroblastoma cell lines.
Topics: Acetylcholinesterase; ADAM Proteins; ADAM10 Protein; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Atropine; Blotting, Western; Brefeldin A; Bungarotoxins; Carbachol; Cell Differentiation; Cell Fractionation; Cell Line, Tumor; Cholinergic Agonists; Cholinesterase Inhibitors; Donepezil; Drug Interactions; Embryo, Mammalian; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; Indans; Membrane Proteins; Metalloendopeptidases; Microscopy, Confocal; Muscarinic Antagonists; Neuroblastoma; Physostigmine; Piperidines; Protein Synthesis Inhibitors; Protein Transport; Tretinoin | 2004 |
Signal transduction underlying carbachol-induced PGE2 generation and cox-1 mRNA expression of rat brain.
Topics: Animals; Carbachol; Cholinergic Agonists; Cyclic GMP; Cyclooxygenase 1; Dinoprostone; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Frontal Lobe; Gene Expression Regulation; Male; Membrane Proteins; Models, Biological; Muscarinic Antagonists; Nitric Oxide Synthase; Phosphatidylinositols; Piperidines; Pirenzepine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction | 2005 |
Stimulation of cannabinoid (CB1) and prostanoid (EP2) receptors opens BKCa channels and relaxes ocular trabecular meshwork.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 8-Bromo Cyclic Adenosine Monophosphate; Adult; Aged; Animals; Benzoxazines; Calcium; Calcium Channel Blockers; Cannabinoids; Carbachol; Cattle; Cells, Cultured; Cholinergic Agonists; Cyclic AMP; Cyclohexanols; Endothelin-1; Humans; In Vitro Techniques; Ion Channel Gating; Middle Aged; Morpholines; Naphthalenes; Patch-Clamp Techniques; Peptides; Piperidines; Potassium Channels, Calcium-Activated; Prostanoic Acids; Pyrazoles; Receptor, Cannabinoid, CB1; Receptors, Prostaglandin E; Stimulation, Chemical; Trabecular Meshwork | 2005 |
Midbrain muscarinic receptor mechanisms underlying regulation of mesoaccumbens and nigrostriatal dopaminergic transmission in the rat.
Topics: Animals; Carbachol; Cholinergic Agonists; Dopamine; Drug Interactions; Electrochemistry; Electrodes; Male; Muscarinic Antagonists; Nucleus Accumbens; Piperidines; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine; Substantia Nigra; Synaptic Transmission; Ventral Tegmental Area | 2005 |
Neuronal nitric oxide synthase activity in rat urinary bladder detrusor: participation in M3 and M4 muscarinic receptor function.
Topics: Animals; Carbachol; Cholinergic Agonists; Cyclic GMP; Dose-Response Relationship, Drug; In Vitro Techniques; Inositol Phosphates; Male; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nitric Oxide Synthase Type I; Piperidines; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Tritium; Tropicamide; Urinary Bladder | 2005 |
M(2) and M(3) muscarinic receptor-mediated contractions in longitudinal smooth muscle of the ileum studied with receptor knockout mice.
Topics: Animals; Calcium Channel Blockers; Carbachol; Cholinergic Agonists; Diamines; Female; Ileum; In Vitro Techniques; Male; Mice; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Nicardipine; Pertussis Toxin; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3 | 2005 |
Regulation of IPSP theta rhythm by muscarinic receptors and endocannabinoids in hippocampus.
Topics: Action Potentials; Amino Acids; Animals; Cannabinoid Receptor Modulators; Carbachol; Cholinergic Agonists; Endocannabinoids; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Male; Methoxyhydroxyphenylglycol; Neural Inhibition; Piperidines; Pyrazoles; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Spectrum Analysis; Synapses; Theta Rhythm; Time Factors; Xanthenes | 2005 |
Neural regulation of slow-wave frequency in the murine gastric antrum.
Topics: Acetylcholine; Androstenes; Animals; Atropine; Benzamides; Benzimidazoles; Carbachol; Electric Stimulation; Electrophysiology; Enteric Nervous System; Female; Gastric Emptying; Male; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Motor Neurons; Muscle Contraction; Myenteric Plexus; Neostigmine; Piperidines; Pyloric Antrum; Tetrodotoxin | 2006 |
Muscarinic M1 and M3 receptor binding alterations in pancreas during pancreatic regeneration of young rats.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Muscarinic Antagonists; Piperidines; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Regeneration | 2005 |
Characterization of muscarinic receptor-mediated cationic currents in longitudinal smooth muscle cells of mouse small intestine.
Topics: Animals; Carbachol; Cations; Cholinergic Agonists; Diamines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Estrenes; Guinea Pigs; In Vitro Techniques; Intestine, Small; Ion Channel Gating; Ion Channels; Male; Membrane Potentials; Mice; Muscarinic Antagonists; Myocytes, Smooth Muscle; Pertussis Toxin; Piperidines; Pyrrolidinones; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Type C Phospholipases | 2006 |
Muscarinic regulation of neonatal rat bladder spontaneous contractions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Calcium Channel Agonists; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Diamines; Electric Stimulation; Muscle Contraction; Muscle Hypertonia; Muscle, Smooth; Parasympatholytics; Peptides; Physostigmine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2006 |
M1 muscarinic receptors contribute to, whereas M4 receptors inhibit, dopamine D1 receptor-induced [3H]-cyclic AMP accumulation in rat striatal slices.
Topics: Alkaloids; Animals; Benzazepines; Carbachol; Cholinergic Agonists; Corpus Striatum; Cyclic AMP; Dopamine Agonists; Furans; Male; Muscarinic Antagonists; N-Methylscopolamine; Naphthalenes; Parasympatholytics; Piperidines; Pirenzepine; Protein Kinase C; Radioligand Assay; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptor, Muscarinic M4; Receptors, Dopamine D1 | 2006 |
Agonist and antagonist sensitivity of non-selective cation channel currents evoked by muscarinic receptor stimulation in bovine ciliary muscle cells.
Topics: Animals; Atropine; Barium; Carbachol; Cattle; Cells, Cultured; Ciliary Body; Dose-Response Relationship, Drug; Membrane Potentials; Microscopy, Fluorescence; Muscarinic Agonists; Muscarinic Antagonists; Muscle Cells; Patch-Clamp Techniques; Piperidines; Pirenzepine; Receptor, Muscarinic M3; TRPC Cation Channels | 2006 |
Regulation of bladder muscarinic receptor subtypes by experimental pathologies.
Topics: Age Factors; Animals; Benzofurans; Carbachol; Denervation; Disease Models, Animal; Electric Stimulation; Female; Gene Expression Regulation; Humans; Hypertrophy; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pyrrolidines; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; RNA, Messenger; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Bladder, Neurogenic | 2006 |
Propiverine and metabolites: differences in binding to muscarinic receptors and in functional models of detrusor contraction.
Topics: Animals; Benzilates; Binding, Competitive; Calcium; Carbachol; Cell Line; Cells, Cultured; CHO Cells; Cholinergic Antagonists; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Electric Stimulation; Epithelial Cells; Humans; Molecular Structure; Muscle Contraction; Muscle, Smooth; N-Methylscopolamine; Parasympatholytics; Piperidines; Potassium Chloride; Receptors, Muscarinic; Urinary Bladder | 2006 |
Functional roles of muscarinic M2 and M3 receptors in mouse stomach motility: studies with muscarinic receptor knockout mice.
Topics: Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Female; Gastric Emptying; Gastric Fundus; Genotype; In Vitro Techniques; Male; Mice; Mice, Inbred Strains; Mice, Knockout; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Physostigmine; Piperidines; Pirenzepine; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Stomach | 2007 |
Human idiopathic and neurogenic overactive bladders and the role of M2 muscarinic receptors in contraction.
Topics: Adult; Aged; Benzofurans; Carbachol; Diamines; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Pyrrolidines; Receptors, Muscarinic; Urinary Bladder; Urinary Bladder, Neurogenic; Urinary Bladder, Overactive | 2007 |
Muscarinic receptor subtypes mediating positive and negative inotropy in the developing chick ventricle.
Topics: Action Potentials; Alkaloids; Animals; Carbachol; Chick Embryo; Dose-Response Relationship, Drug; Furans; Heart Ventricles; Myocardial Contraction; Naphthalenes; Piperidines; Pirenzepine; Receptors, Muscarinic | 2007 |
TRPV1 is involved in stretch-evoked contractile changes in the rat autonomous bladder model: a study with piperine, a new TRPV1 agonist.
Topics: Alkaloids; Animals; Benzodioxoles; Capsaicin; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Female; Indicators and Reagents; Mechanotransduction, Cellular; Muscle Contraction; Piperidines; Polyunsaturated Alkamides; Pressure; Rats; Rats, Wistar; Ruthenium Red; Stress, Mechanical; TRPV Cation Channels; Urinary Bladder | 2007 |
Cardiovascular effects of carbachol microinjected into the bed nucleus of the stria terminalis of the rat brain.
Topics: Animals; Arginine Vasopressin; Atropine; Blood Pressure; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Drug Interactions; Heart Rate; Male; Microinjections; Muscarinic Antagonists; Nicotinic Antagonists; Pentolinium Tartrate; Piperidines; Rats; Rats, Wistar; Septal Nuclei | 2007 |
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection | 2007 |
Endothelin, PAF and thromboxane A2 in allergic pulmonary hyperreactivity in mice.
Topics: Animals; Antihypertensive Agents; Bronchial Hyperreactivity; Carbachol; Endothelin B Receptor Antagonists; Endothelin-1; Endothelins; Male; Mice; Mice, Inbred BALB C; Oligopeptides; Ovalbumin; Peptide Fragments; Phospholipid Ethers; Piperidines; Platelet Activating Factor; Platelet Aggregation Inhibitors; Prostaglandin Endoperoxides, Synthetic; Receptor, Endothelin B; Thromboxane A2 | 2007 |
Cholinergic activation of phasic activity in the isolated bladder: possible evidence for M3- and M2-dependent components of a motor/sensory system.
Topics: Animals; Arecoline; Benzofurans; Carbachol; Cholinergic Agonists; Female; Guinea Pigs; Muscarinic Agonists; Piperidines; Pyrrolidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder; Urination | 2007 |
Lack of depolarization-induced suppression of inhibition (DSI) in layer 2/3 interneurons that receive cannabinoid-sensitive inhibitory inputs.
Topics: Action Potentials; Animals; Animals, Newborn; Benzoxazines; Calcium; Cannabinoids; Carbachol; Cerebral Cortex; Cholinergic Agonists; Dose-Response Relationship, Radiation; Electric Stimulation; In Vitro Techniques; Interneurons; Mice; Morpholines; Naphthalenes; Neural Inhibition; Piperidines; Pyramidal Cells; Pyrazoles; Rimonabant | 2007 |
Changes in muscarinic receptors in the toad urothelial cell line TBM-54 following acrolein treatment.
Topics: Acrolein; Animals; Blotting, Western; Bufo marinus; Carbachol; Cell Line; Diamines; Dose-Response Relationship, Drug; Extracellular Fluid; Hydrogen-Ion Concentration; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptors, Muscarinic; Urinary Bladder; Urothelium | 2008 |
Endothelin receptor blockers protect against ischemia/reperfusion impairment of gastrointestinal motility in rats.
Topics: Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Carbachol; Dose-Response Relationship, Drug; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin Receptor Antagonists; Endothelin-1; Ether; Evans Blue; Gastrointestinal Motility; Male; Muscarinic Agonists; Oligopeptides; Peptides, Cyclic; Piperidines; Pyridines; Rats; Rats, Wistar; Reperfusion Injury; Surgical Procedures, Operative; Tetrazoles | 2008 |
Refractoriness of the sheep superior vena cava myocardial sleeve.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Diamines; Electrophysiologic Techniques, Cardiac; In Vitro Techniques; Microelectrodes; Muscarinic Antagonists; Myocardium; Myocytes, Cardiac; Piperidines; Refractometry; Sheep; Tropicamide; Vasodilator Agents; Vena Cava, Superior | 2008 |
Activation of cholinergic receptors blocks non-adrenergic non-cholinergic contractions in the rat urinary bladder.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Antineoplastic Agents; Atropine; Calcium Channel Agonists; Carbachol; Cholinergic Agonists; Cholinesterase Inhibitors; Electric Stimulation; Female; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Physostigmine; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Suramin; Urinary Bladder | 2008 |
Islet neogenesis-associated protein signaling in neonatal pancreatic rat islets: involvement of the cholinergic pathway.
Topics: Animals; Animals, Newborn; Antigens, Neoplasm; Biomarkers, Tumor; Carbachol; Carrier Proteins; Immunoblotting; In Vitro Techniques; Insulin; Islets of Langerhans; Lectins, C-Type; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Pancreatitis-Associated Proteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Piperidines; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; TOR Serine-Threonine Kinases | 2008 |
ETB2 receptor subtype stimulation relaxes the iris sphincter muscle.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Endothelin-1; Endothelins; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Iris; Male; Muscle Relaxation; Muscle, Smooth; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oligopeptides; Peptide Fragments; Peptides; Piperidines; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rabbits; Receptor, Endothelin A; Receptor, Endothelin B; Viper Venoms | 2009 |
Inhibitory effect of quercetin on rat trachea contractility in vitro.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Antioxidants; Benzamides; Capsaicin; Carbachol; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Neurokinin-1 Receptor Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phentolamine; Piperidines; Propranolol; Quercetin; Quinuclidines; Rats; Rats, Wistar; Receptors, Neurokinin-2; Trachea | 2009 |
In vitro and in vivo pharmacological characterization of PF-01354082, a novel partial agonist selective for the 5-HT(4) receptor.
Topics: Administration, Oral; Animals; Benzimidazoles; Carbachol; Cell Line; CHO Cells; Cholinergic Agonists; Cricetinae; Cricetulus; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Esophagus; Gastrointestinal Motility; Humans; Indoles; Kidney; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Rats; Rats, Inbred Strains; Sensitivity and Specificity; Serotonin 5-HT4 Receptor Agonists; Serotonin 5-HT4 Receptor Antagonists; Serotonin Receptor Agonists; Time Factors | 2009 |
Muscarinic receptor-mediated nitric oxide release in a K562 erythroleukaemia cell line.
Topics: Arginine; Carbachol; Chromatography, High Pressure Liquid; Citrulline; Dose-Response Relationship, Drug; Humans; K562 Cells; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Nitric Oxide; Nitric Oxide Synthase; Piperidines; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tropicamide | 2009 |
Carbachol regulates pacemaker activities in cultured interstitial cells of Cajal from the mouse small intestine.
Topics: Animals; Anti-Inflammatory Agents; Biological Clocks; Calcium; Calcium-Transporting ATPases; Carbachol; Cation Transport Proteins; Cells, Cultured; Diamines; Flufenamic Acid; Guanosine Diphosphate; Intestine, Small; Membrane Potentials; Mice; Mice, Inbred BALB C; Neuromuscular Depolarizing Agents; Patch-Clamp Techniques; Piperidines; Plant Roots; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Thapsia; Thapsigargin; Thionucleotides | 2009 |
Muscarinic receptor type 1 (M1) stimulation, probably through KCNQ/Kv7 channel closure, increases spontaneous GABA release at the dendrodendritic synapse in the mouse accessory olfactory bulb.
Topics: Alkaloids; Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels, R-Type; Carbachol; Carbamates; Cholinergic Agonists; Dendrites; Diclofenac; Excitatory Amino Acid Antagonists; Furans; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Ion Channel Gating; KCNQ Potassium Channels; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Naphthalenes; Nimodipine; Olfactory Bulb; Patch-Clamp Techniques; Phenylenediamines; Piperidines; Pirenzepine; Potassium Channel Blockers; Receptor, Muscarinic M1; Receptors, Glutamate; Synapses | 2010 |
Muscarinic receptors induce LTD of NMDAR EPSCs via a mechanism involving hippocalcin, AP2 and PSD-95.
Topics: Acetylcholine; Adaptor Protein Complex 2; Animals; Biophysics; Calcium; Carbachol; Cholinergic Agonists; Disks Large Homolog 4 Protein; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Hippocalcin; Hippocampus; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Long-Term Synaptic Depression; Male; Membrane Proteins; Muscarinic Antagonists; Patch-Clamp Techniques; Piperidines; Protein Transport; Quinolones; Rats; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; RNA Interference; Synapses; Two-Hybrid System Techniques | 2010 |
Chemical stimulation of the lateral hypothalamus induces conditioned place preference in rats: Involvement of OX1 and CB1 receptors in the ventral tegmental area.
Topics: Animals; Benzoxazoles; Carbachol; Choice Behavior; Conditioning, Operant; Dose-Response Relationship, Drug; Hypothalamic Area, Lateral; Male; Naphthyridines; Neural Pathways; Orexin Receptors; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor Cross-Talk; Receptor, Cannabinoid, CB1; Receptors, G-Protein-Coupled; Receptors, Neuropeptide; Reward; Urea; Ventral Tegmental Area | 2011 |
Selective M3 muscarinic receptor antagonist inhibits small-cell lung carcinoma growth in a mouse orthotopic xenograft model.
Topics: Animals; Antineoplastic Agents; Calcium Signaling; Carbachol; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dipeptides; Dose-Response Relationship, Drug; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred ICR; Mice, SCID; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Receptor, Muscarinic M3; Small Cell Lung Carcinoma; Tumor Burden; Xenograft Model Antitumor Assays | 2011 |
Plasticity of non-adrenergic non-cholinergic bladder contractions in rats after chronic spinal cord injury.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Carbachol; Cholinergic Agonists; Female; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Neuronal Plasticity; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, Purinergic; Spinal Cord Injuries; Urinary Bladder | 2011 |
Muscarinic activation of Ca2+-activated Cl- current in interstitial cells of Cajal.
Topics: Animals; Atropine; Carbachol; Chloride Channels; Green Fluorescent Proteins; Interstitial Cells of Cajal; Intestine, Small; Membrane Potentials; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Animal; Muscarinic Agonists; Muscarinic Antagonists; Patch-Clamp Techniques; Piperidines; Receptors, Muscarinic | 2011 |
Expression of muscarinic receptors by human macrophages.
Topics: Carbachol; Cells, Cultured; Choline O-Acetyltransferase; Humans; Interleukin-6; Interleukin-8; Leukocytes, Mononuclear; Leukotriene B4; Macrophages; Membrane Transport Proteins; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pulmonary Disease, Chronic Obstructive; Receptors, Muscarinic; RNA; Smoking; Vesicular Acetylcholine Transport Proteins | 2012 |
Effects of cannabinoid agonists on sheep sphincter of oddi in vitro.
Topics: Analgesics; Animals; Arachidonic Acids; Benzoxazines; Camphanes; Cannabinoid Receptor Agonists; Cannabinoids; Carbachol; Cyclic GMP; Male; Morpholines; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Naphthalenes; NG-Nitroarginine Methyl Ester; Organ Culture Techniques; Piperidines; Pyrazoles; Rimonabant; Sheep; Sphincter of Oddi | 2011 |
Urothelial/lamina propria spontaneous activity and the role of M3 muscarinic receptors in mediating rate responses to stretch and carbachol.
Topics: Animals; Atropine; Benzhydryl Compounds; Benzofurans; Carbachol; Cresols; Diamines; Mandelic Acids; Mucous Membrane; Muscarinic Antagonists; Muscle Contraction; Phenylpropanolamine; Piperidines; Pirenzepine; Pyrrolidines; Quinuclidines; Receptor, Muscarinic M3; Solifenacin Succinate; Stress, Mechanical; Swine; Tetrahydroisoquinolines; Tolterodine Tartrate; Urinary Bladder; Urothelium | 2011 |
Pharmacological characterization of GSK1004723, a novel, long-acting antagonist at histamine H(1) and H(3) receptors.
Topics: Allergens; Animals; Benzazepines; Binding, Competitive; Bronchi; Bronchial Provocation Tests; Bronchoconstriction; Carbachol; Cell Line; CHO Cells; Cricetinae; Cricetulus; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Histamine H3 Antagonists; Humans; In Vitro Techniques; Niacinamide; Ovalbumin; Phthalazines; Piperidines; Pyrilamine; Receptors, Histamine H1; Receptors, Histamine H3; Recombinant Proteins; Rhinitis, Allergic, Perennial; Transfection | 2011 |
Influence of influenza A infection on capsaicin-induced responses in murine airways.
Topics: Animals; Biphenyl Compounds; Bronchoalveolar Lavage Fluid; Capsaicin; Carbachol; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Indomethacin; Inflammation; Influenza A virus; Isoproterenol; Leukocytes; Male; Mice; Mice, Inbred BALB C; Models, Biological; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Orthomyxoviridae Infections; Piperidines; Prostaglandin Antagonists; Respiratory Mucosa; Specific Pathogen-Free Organisms; Substance P; Trachea; TRPV Cation Channels; Xanthones | 2012 |
Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle.
Topics: Amides; Calcium; Carbachol; Enzyme Inhibitors; Humans; In Vitro Techniques; Indoles; Maleimides; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxants, Central; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Piperidines; Pirenzepine; Protein Kinase C; Pyridines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; rho-Associated Kinases; Signal Transduction; Urinary Bladder | 2012 |
Muscarinic receptor subtypes involved in urothelium-derived relaxatory effects in the inflamed rat urinary bladder.
Topics: Animals; Carbachol; Cyclophosphamide; Cystitis; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Muscarinic Antagonists; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Nitric Oxide Synthase; Nitroarginine; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Urinary Bladder; Urothelium | 2012 |
Signaling cross-talk between cannabinoid and muscarinic systems actives Rho-kinase and increases the contractile responses of the bovine ciliary muscle.
Topics: Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Carbachol; Cattle; Cholinergic Agonists; Ciliary Body; Endocannabinoids; In Vitro Techniques; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Polyunsaturated Alkamides; Protein Kinase C; Pyrazoles; Receptor, Cannabinoid, CB1; Receptor, Muscarinic M3; rho-Associated Kinases | 2013 |
A role for M(2) and M(3) muscarinic receptors in the contraction of rat and human small airways.
Topics: Animals; Carbachol; Cholinergic Agonists; Humans; In Vitro Techniques; Lung; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Scopolamine Derivatives; Tiotropium Bromide | 2013 |
Loss of TRPM2 function protects against irradiation-induced salivary gland dysfunction.
Topics: Acinar Cells; Animals; Benzamides; Calcium; Carbachol; Cell Line; Cell Survival; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Ion Channel Gating; Mice; Mice, Inbred C57BL; Piperidines; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Radiation Injuries; Saliva; Salivary Glands; Salivation; Submandibular Gland; TRPM Cation Channels; X-Rays | 2013 |
Different muscarinic receptor subtypes modulate proliferation of primary human detrusor smooth muscle cells via Akt/PI3K and map kinases.
Topics: Aged; Atropine; Benzofurans; Carbachol; Cell Proliferation; Cells, Cultured; Cholinergic Agonists; Gene Expression; Humans; Male; Mitogen-Activated Protein Kinases; Muscarinic Antagonists; Myocytes, Smooth Muscle; Phosphatidylinositol 3-Kinases; Piperidines; Pirenzepine; Proto-Oncogene Proteins c-akt; Pyrrolidines; Receptors, Muscarinic; RNA, Messenger; Urinary Bladder | 2013 |
Activation of muscarinic M3 receptors inhibits large-conductance voltage- and Ca2+-activated K+ channels in rat urinary bladder smooth muscle cells.
Topics: Amphotericin B; Animals; Carbachol; Cholinergic Agonists; Diamines; Evoked Potentials; Gene Expression Regulation; Large-Conductance Calcium-Activated Potassium Channels; Male; Membrane Potentials; Muscarinic Antagonists; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M3; Urinary Bladder | 2013 |
The inhibitory effects of antimuscarinic autoantibodies in the sera of primary Sjogren syndrome patients on the gastrointestinal motility.
Topics: Animals; Autoantibodies; Carbachol; Cholinergic Agonists; Colon; Diamines; Dose-Response Relationship, Drug; Gastrointestinal Motility; Humans; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Piperidines; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Sjogren's Syndrome; Stomach | 2013 |
Bladder function in a cannabinoid receptor type 1 knockout mouse.
Topics: Animals; Cannabinoid Receptor Antagonists; Carbachol; Female; Mice; Mice, Inbred C57BL; Mice, Knockout; Muscle Contraction; Muscle, Smooth; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant; Urinary Bladder; Urination; Urodynamics | 2014 |
Expression and function of muscarinic subtype receptors in bladder interstitial cells of cajal in rats.
Topics: Action Potentials; Animals; Atropine; Calcium Channels; Carbachol; Cholinergic Agonists; Diamines; Interstitial Cells of Cajal; Male; Muscarinic Antagonists; Patch-Clamp Techniques; Piperidines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Urinary Bladder | 2014 |
Excitatory drive from the Subthalamic nucleus attenuates GABAergic transmission in the Substantia Nigra pars compacta via endocannabinoids.
Topics: Animals; Carbachol; Chromones; Dopaminergic Neurons; Electric Stimulation; Endocannabinoids; Excitatory Postsynaptic Potentials; GABAergic Neurons; Inhibitory Postsynaptic Potentials; Pars Compacta; Pars Reticulata; Piperidines; Pyrazoles; Rats; Rimonabant; Subthalamic Nucleus; Synaptic Transmission | 2015 |
Functional interaction between OX2 and CB1 receptors in the ventral tegmental area and the nucleus accumbens in response to place preference induced by chemical stimulation of the lateral hypothalamus.
Topics: Animals; Carbachol; Conditioning, Psychological; Dose-Response Relationship, Drug; Drug Synergism; Hypothalamic Area, Lateral; Isoquinolines; Male; Microinjections; Nucleus Accumbens; Orexin Receptor Antagonists; Orexin Receptors; Piperidines; Pyrazoles; Pyridines; Rats; Receptor, Cannabinoid, CB1; Reward; Stimulation, Chemical; Ventral Tegmental Area | 2015 |
Functional interaction between orexin-1 and CB1 receptors in the periaqueductal gray matter during antinociception induced by chemical stimulation of the lateral hypothalamus in rats.
Topics: Animals; Benzoxazoles; Carbachol; Disease Models, Animal; Hypothalamic Area, Lateral; Male; Microinjections; Naphthyridines; Orexin Receptors; Orexins; Pain; Pain Measurement; Periaqueductal Gray; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Stimulation, Chemical; Urea | 2016 |
Role of orexin-2 and CB1 receptors within the periaqueductal gray matter in lateral hypothalamic-induced antinociception in rats.
Topics: Animals; Carbachol; Disease Models, Animal; Dose-Response Relationship, Drug; Hypothalamic Area, Lateral; Isoquinolines; Male; Orexin Receptor Antagonists; Orexin Receptors; Orexins; Pain; Periaqueductal Gray; Piperidines; Pyrazoles; Pyridines; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1 | 2017 |
Intrinsic membrane properties and cholinergic modulation of mouse basal forebrain glutamatergic neurons in vitro.
Topics: Action Potentials; Animals; Animals, Genetically Modified; Animals, Newborn; Basal Forebrain; Benzamides; Calcium Channel Blockers; Carbachol; Cholinergic Agents; Electric Stimulation; Glutamates; Luminescent Proteins; Lysine; Mice; Neurons; Patch-Clamp Techniques; Piperidines; Pyrimidines; Red Fluorescent Protein; Sodium Channel Blockers; Tetrodotoxin; Vesicular Glutamate Transport Protein 2 | 2017 |
Relaxant effect of ghrelin on guinea pig isolated tracheal smooth muscle: role of epithelial NO and PGE
Topics: Animals; Carbachol; Dinoprostone; Ghrelin; Guinea Pigs; Histamine; Indomethacin; Male; Muscle Relaxation; Muscle, Smooth; NG-Nitroarginine Methyl Ester; Nitric Oxide; Piperidines; Quinazolinones; Respiratory Mucosa; Trachea | 2018 |
Novel BQCA- and TBPB-Derived M
Topics: Benzimidazoles; Carbachol; Drug Partial Agonism; HEK293 Cells; Humans; Ligands; Molecular Docking Simulation; Muscarinic Agonists; Piperidines; Quinolines; Receptor, Muscarinic M1 | 2019 |
Central muscarinic receptor subtypes (M1 and M3) involved in carbacol-induced hypophagia in neonatal broiler chicken.
Topics: Animals; Animals, Newborn; Behavior, Animal; Carbachol; Chickens; Disease Models, Animal; Eating; Injections, Intraventricular; Muscarinic Agonists; Muscarinic Antagonists; Piperidines; Pirenzepine; Receptor, Muscarinic M1; Receptor, Muscarinic M3 | 2020 |