carbachol has been researched along with oxotremorine in 278 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 159 (57.19) | 18.7374 |
| 1990's | 91 (32.73) | 18.2507 |
| 2000's | 23 (8.27) | 29.6817 |
| 2010's | 4 (1.44) | 24.3611 |
| 2020's | 1 (0.36) | 2.80 |
| Authors | Studies |
|---|---|
| Chapman, JM; Kosh, JW; Sowell, JW; Tang, Y; Valli, MJ | 1 |
| Hacksell, U; Nilsson, BM; Vargas, HM | 1 |
| Chapman, JM; Kosh, JW; Sowell, JW; Tang, Y; Usher, LA; Valli, MJ; Vaughan, CM | 1 |
| Amstutz, R; Boelsterli, J; Bolliger, G; Floersheim, P; Gammenthaler, H; Gmelin, G; Shapiro, G; Supavilai, P; Walkinshaw, M | 1 |
| Baumgold, J; Bradbury, BJ; Jacobson, KA; Kammula, U; Paek, R; Zimmet, J | 1 |
| Kramss, RH; Mangano, RM; Rusinko, A; Trybulski, EJ | 1 |
| Jenden, DJ; Ringdahl, B; Roch, M | 1 |
| Ringdahl, B | 4 |
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Brann, MR; Bräuner-Osborne, H; Ebert, B; Falch, E; Krogsgaard-Larsen, P | 1 |
| Kramss, RH; Mangano, RM; Trybulski, EJ; Zhang, J | 1 |
| Abuh, YF; Dunbar, PG; Edgar, MA; El-Assadi, AA; Fang, Z; Huzl, JJ; Liu, Y; Messer, WS; Nagy, PI; Ngur, DO; Ojo, B; Periyasamy, S; Rho, T; Roknich, S; Sbeih, S; Zhang, H | 1 |
| Bromidge, SM; Brown, F; Cassidy, F; Clark, MS; Dabbs, S; Hadley, MS; Hawkins, J; Loudon, JM; Naylor, CB; Orlek, BS; Riley, GJ | 1 |
| Daly, JW; Gupta, TH; Padgett, WL; Pei, XF | 1 |
| Chen, D; Shan, L; Wang, H; Yang, R; Yun, L; Zhao, R | 1 |
| Dei, S; Marconi, C; Pedretti, A; Romanelli, MN; Scapecchi, S; Vistoli, G | 1 |
| Lamble, AP; Lamble, JW | 1 |
| Gray, DB; Lane, MA; Sastre, A | 1 |
| Birdsall, NJ; Burgen, AS; Strange, PG | 1 |
| Makara, GB; Stark, E | 1 |
| Maayani, S; Sokolovsky, M; Treister, G | 1 |
| Bianchetti, A; Biraschi, LM; Guarneri, L; Riva, M | 1 |
| Brezenoff, HE; Buccafusco, JJ | 1 |
| Aktories, K; Jakobs, KH; Schultz, G | 1 |
| Bhargava, VK; McKean, CM; Salamy, A | 2 |
| Hadházy, P; Szerb, JC | 1 |
| Dudar, JD; Hadházy, P; Szerb, JC | 1 |
| Ehlert, FJ; Kokka, N | 1 |
| Staib, AH; Westermann, KH | 1 |
| Johnson, KG | 1 |
| Funk, KF; Oelszner, W; Schwarzenfeld, IV; Staib, AH; Westermann, KH | 1 |
| Lindenboim, L; Pinkas-Kramarski, R; Sokolovsky, M; Stein, R | 1 |
| Morrison, KJ; Vanhoutte, PM | 1 |
| Hato, F; Kinoshita, Y; Tominaga, K; Tominaga, M; Yamada, M | 1 |
| Bungardt, E; Feifel, R; Lambrecht, G; Moser, U; Mutschler, E; Surprenant, A; Tacke, R; Vockert, E | 1 |
| Joseph, JA; Roth, GS; Yamagami, K | 1 |
| Mochizuki, D; Shinoda, Y; Sugiyama, S | 1 |
| Constanti, A; Das, B; Libri, V | 1 |
| Gies, JP; Haddad, EB | 1 |
| Dunant, Y; Sierro, CD; Vitus, J | 1 |
| Bhattacharya, SK; Das Gupta, G; Sen, AP; Seth, K; Seth, PK | 1 |
| Althaus, JS; Buxser, SE; Decker, DE; Von Voigtlander, PF | 1 |
| Gies, JP; Haddad, EB; Landry, Y | 1 |
| Daniel, EE; Janssen, LJ | 1 |
| Chilvers, ER; Nahorski, SR; Offer, GJ | 1 |
| Lovenberg, TW; Mailman, RB; Nichols, DE; Roth, RH | 1 |
| Aksoy, S; Gibson, VA; McKinney, M; Miller, JH; Nickelson, L | 1 |
| Fujimoto, S; Matsuda, T | 1 |
| Ebadi, M; Govitrapong, P; Pujito, PP | 1 |
| Richards, MH | 1 |
| Joseph, JA; Kowatch, MA; Maki, T; Roth, GS | 1 |
| Schimerlik, MI; Tota, MR | 1 |
| de Pont, JJ; Rodrigues de Miranda, JF; van Ginneken, CA; van Zwam, AJ; Willems, PH | 1 |
| Costi, A; Marchi, M; Raiteri, M; Volpe, G | 1 |
| Bagetta, G; Constanti, A | 1 |
| Ikeda, T; Kojima, T; Shirasu, Y; Takahashi, H; Tsuda, S; Yoshida, M | 1 |
| Bartolami, S; Guiramand, J; Lenoir, M; Mayat, E; Pujol, R; Récasens, M; Rumigny, JF | 1 |
| Baum, BJ; He, XJ; Turner, RJ; Wu, XZ | 1 |
| Ehlert, FJ; Rathbun, BE | 1 |
| Bartus, RT; Fisher, SK | 1 |
| Nezu, E; Yoneyama, T; Yoshimura, K | 1 |
| Cohen-Armon, M; Sokolovsky, M | 1 |
| Pappano, AJ; Tajima, T; Tsuji, Y; Yuen, J | 1 |
| Baumgold, J; Fishman, PH | 1 |
| Fertel, R; Hadjiconstantinou, M; Neff, NH; Qu, ZX | 1 |
| Arrang, JM; Gulat-Marnay, C; Lafitte, A; Schwartz, JC | 1 |
| Henis, YI; Moscona-Amir, E; Sokolovsky, M | 1 |
| Luthin, GR; Manning, DR; Matesic, DF; Wolfe, BB | 1 |
| Lang, U; Walland, A | 1 |
| Matsumoto, K; Pappano, AJ | 1 |
| Marchi, M; Raiteri, M | 1 |
| Drews, U; Oettling, G; Schmidt, H | 2 |
| Gil, DW; Wolfe, BB | 1 |
| Imaizumi, T; Misaki, N; Mizushima, A; Osugi, T; Tatebayashi, Y; Uchida, S; Yoshida, H; Zhou, XM | 1 |
| Flynn, DD; Palermo, N; Suarez, A | 1 |
| Good, DM; Small, RC | 1 |
| Boselli, C; Kenakin, T | 1 |
| Boddeke, HW; Doods, HN; Rondas, AA; Thörig, L; van Haeringen, NJ; van Zwieten, PA | 1 |
| Borasio, PG; Capuzzo, A; Fabbri, E | 1 |
| Ashkenazi, A; Capon, DJ; Peralta, EG; Peterson, GL; Ramachandran, J; Schimerlik, MI; Winslow, JW | 1 |
| Baraban, JM; Heller, WA; Snyder, SH; Worley, PF | 1 |
| Chen, WY; Wince, LC | 1 |
| Pinkas-Kramarski, R; Sokolovsky, M; Stein, R | 1 |
| Alger, BE; McCarren, M; Pitler, TA | 1 |
| Ek, B; Nahorski, S | 1 |
| Critchett, DJ; Joseph, JA; Lippa, AS | 1 |
| Costa, E; Eva, C | 2 |
| Baux, G; Fossier, P; Poulain, B; Tauc, L | 1 |
| Dalton, TK; Hunt, WA; Joseph, JA | 1 |
| Anderson, W; Dickinson, KE; Hirschowitz, BI; Matsumoto, H; Pruitt, RE; Uemura, N | 1 |
| Baraban, JM; Huganir, RL; Stratton, KR; Worley, PF | 1 |
| Amstutz, R; Jenden, DJ; Karlén, B; Ringdahl, B; Roch, M | 1 |
| Cantin, M; Garcia, R; Gutkowska, J; Lachance, D; Thibault, G | 1 |
| Limas, C; Limas, CJ | 1 |
| Heisler, S | 1 |
| Gjörstrup, P; Hjalmarson, A; Jacobsson, B; Ransnäs, L; Sjögren, CG | 1 |
| Brown, JH; Harden, TK; Heng, MM | 1 |
| Chuang, DM; Xu, J | 1 |
| DeGeorge, JJ; Lapetina, EG; McCarthy, KD; Morell, P | 1 |
| Channell, SL; Iversen, SD; Lalies, MD; Salamone, JD | 1 |
| Alger, BE; Baraban, JM; McCarren, M; Snyder, SH; Worley, PF | 1 |
| Crain, B; Crain, SM; Makman, MH | 2 |
| Aronstam, RS; Narayanan, TK | 1 |
| Bertrand, C; Gies, JP; Landry, Y | 1 |
| Anthony, BL; Aronstam, RS; Dennison, RL; Narayanan, TK | 1 |
| Lüllmann, H; Mohr, K; Pfeffer, J | 1 |
| Galron, R; Sokolovsky, M | 1 |
| Erwin, VG; Jones, BC; Korte, A | 1 |
| Amstutz, R; Closse, A; Ringdahl, B | 1 |
| Camus, J; Christophe, J; De Neef, P; Fourmy, D; Pradayrol, L; Robberecht, P; Scemama, JL; Tastenoy, M; Vaysse, N; Waelbroeck, M | 1 |
| Band, LC; Bitran, D; Clemens, LG; Holmes, GM; Hull, EM; Pehek, EA; Warner, RK | 1 |
| Fujii, AM; Homcy, CJ; Lee, DL; Longabaugh, JP; Schwarz, KR; Vatner, DE; Vatner, SF | 1 |
| Abdel-Latif, AA; Honkanen, RE | 1 |
| Crain, SM; Makman, MH | 1 |
| Gies, JP; Landry, Y | 1 |
| Sokolovsky, M; van Koppen, CJ | 1 |
| Dutar, P; Nicoll, RA | 1 |
| Adem, A; Nordberg, A; Sabbagh, M | 1 |
| Constanti, A; Williams, SH | 2 |
| Hynie, S | 1 |
| Stojić, D; Terzić, M | 1 |
| Bonaventure, N; Jardon, B; Rudolf, G; Wioland, N | 1 |
| Collins, SM; Crankshaw, DJ | 1 |
| Markowicz, ME; Ringdahl, B | 1 |
| Christophe, J; Gillard, M; Waelbroeck, M | 1 |
| Bartfai, T; Hedlund, B | 1 |
| Collins, AC; Marks, MJ; Romm, E | 1 |
| Green, RD; Hosey, MM; Kwatra, MM; Leung, E; Maan, AC; McMahon, KK; Ptasienski, J | 1 |
| Pittaluga, A; Raiteri, M | 1 |
| Clemens, LG; Richmond, G | 1 |
| Anthony, BL; Aronstam, RS | 1 |
| Horváth, E; Spencer, DG; Traber, J; Van Rooijen, LA | 1 |
| Chien, JL; Warren, JR | 1 |
| Baker, SP; Posner, P | 1 |
| Johnston, CI; Leung, E; Woodcock, EA | 1 |
| Barenholz, Y; Henis, YI; Moscona-Amir, E; Sokolovsky, M; Yechiel, E | 1 |
| Bering, B; Müller, WE | 1 |
| Cubeddu, LX; James, MK | 1 |
| Luthin, GR; Wolfe, BB | 1 |
| Henry, PJ; Lulich, KM; Paterson, JW | 1 |
| Flynn, DD; Potter, LT | 1 |
| Barker, DL; Mpitsos, GJ; Murray, TF; Siebenaller, JF | 1 |
| Kloog, Y; Sokolovsky, M | 1 |
| Konno, F; Takayanagi, I | 1 |
| Gurwitz, D; Sokolovsky, M | 1 |
| Ehlert, FJ | 1 |
| Eriksson, H; Häggblad, J; Heilbronn, E | 1 |
| Higuchi, H; Kagiya, T; Matsumoto, K; Mizushima, A; Osugi, T; Uchida, S; Yoshida, H; Zhou, XM | 1 |
| Bianchi, C; Tomasi, L | 1 |
| Snyder, SH; Yamamura, HI | 1 |
| Blanton, RJ; Komiskey, HL; Rudy, TA | 1 |
| Bhargava, AK; Bhargava, KP; Tangri, KK | 1 |
| György, L; Phan, DV; Szelényi, Z; Varga, B | 1 |
| Johnson, KG; Smith, CA | 1 |
| Fozard, JR; Muscholl, E | 1 |
| Birdsall, NJ; Burgen, A; Hulme, EC | 1 |
| Abeln, W; Bienhold, H; Flohr, H | 1 |
| Kanje, M; Lazarewicz, JW | 1 |
| Peterfreund, RA; Vale, WW | 1 |
| Kerkerian, L; Nieoullon, A | 1 |
| Kuwata, K; Nagai, K; Okamoto, E; Toyosaka, A; Uchida, S; Ueki, S; Yoshida, H | 1 |
| Jenden, DJ; Ringdahl, B | 1 |
| Brown, BL; Dobson, PR; Wojcikiewicz, RJ | 1 |
| Cortés, R; Palacios, JM; Pazos, A | 1 |
| Barhanin, J; Cavey, D; Fosset, M; Lazdunski, M; Renaud, JF | 1 |
| Blandina, P; Fantozzi, R; Mannaioni, PF; Masini, E | 1 |
| Brown, JH; Rietow, M | 1 |
| Harden, TK; Meeker, RB | 1 |
| Brown, JH; Brown, SL | 1 |
| Dahlbom, R; Ehlert, FJ; Jenden, DJ; Resul, B; Ringdahl, B | 1 |
| Bergh, CH; Hjalmarson, A; Jacobsson, B; Ransnäs, L; Waldenström, A | 1 |
| Barr, PJ; Clemens, LG; Dohanich, GP; Witcher, JA | 1 |
| Hauser, G; Parks, JM | 1 |
| Asselin, J; Christophe, J; de Neef, P; Robberecht, P; Waelbroeck, M | 1 |
| Birdsall, NJ; Burgen, AS; Hulme, EC; Wong, EH | 1 |
| Cheong, DK; Misgeld, U; Weiler, MH | 1 |
| Halvorsen, SW; Holttum, J; Hunter, DD; Nathanson, NM | 1 |
| North, RA; Tokimasa, T | 1 |
| Klein, WL; Siman, RG | 1 |
| Leung, E; Mitchelson, F | 1 |
| Dial, E; Ecknauer, R; Johnson, LR; Rosenfeld, GC; Thompson, WJ | 1 |
| Coppi, G; Leone, L; Lumachi, B; Rossini, L; Valsecchi, B | 1 |
| Kwok, YH; Mitchelson, F | 1 |
| Gainer, MW; Meyer, MR; Nathanson, NM | 1 |
| Westermann, KH | 1 |
| Bhargava, VK; Pushpavati, CP | 1 |
| Bartfai, T; Hedlund, B; Järv, J | 1 |
| Klein, WL; Shifrin, GS | 1 |
| Ellis, J; Hoss, W | 1 |
| Miller, DA; Pendleton, RG; Ridley, PT | 1 |
| Ehlert, FJ; Fairhurst, AS; Kokka, N | 1 |
| Bauer, MB; Gebhart, GF; Murphy, S | 1 |
| Birmingham, AT; Harriss, DR; Hill, SJ; Marsh, KA | 1 |
| Ogren, SO; Pramanik, A | 1 |
| Gabelt, BT; Kaufman, PL; Poyer, JF | 1 |
| Dorsey, WC; Ford, BD; Townsel, JG | 1 |
| Ferrari-DiLeo, G; Flynn, DD; Mash, DC | 1 |
| Denisova, NA; Erat, S; Joseph, JA; Kelly, JF; Mason, RP; Roth, GS | 1 |
| Honda, K; Kamiya, H; Takano, Y | 1 |
| Haass, M; Haunstetter, A; Krüger, C; Kübler, W; Yi, X | 1 |
| Hadjiconstantinou, M; Hubble, JP; Neff, NH; Wemlinger, TA | 1 |
| Nahorski, SR; Safrany, ST | 1 |
| Martin, DL; Waniewski, RA | 1 |
| Dalton, TK; Harris, A; Joseph, JA; Kandasamy, S; Rabin, BM; Villalobos-Molina, R | 1 |
| Bowen, WD; de Costa, BR; Kirschner, BN; Rice, KC; Tolentino, PJ; Varghese, P | 1 |
| Clement, JG | 1 |
| Belton, CM; Fatherazi, S; Herrington, J; Izutsu, KT; Oda, D; Wellner, RB | 1 |
| Allaoua, H; Alonso, R; Boksa, P; Chaudieu, I; Quirion, R | 1 |
| Castoldi, AF; Costa, LG; Tang, C | 1 |
| Antonsson, BM; Ek, B | 1 |
| Habecker, BA; Nathanson, NM; Wang, H | 1 |
| Eglen, RM; Sharif, NA; To, ZP | 1 |
| Consolo, S; Garcia Ruiz, AJ; La Porta, C; Ladinsky, H; Zambelli, M | 1 |
| Tonnaer, JA; van Huizen, F | 1 |
| Contrera, JG; Holopainen, I; Mcleskey, SW; Wojcik, WJ; Xu, J | 1 |
| Abood, LG; Hashmi, M; Lerner-Marmarosh, N; Saraswati, M | 1 |
| Jones, SB; King, LB | 1 |
| Barg, J; Fisher, A; Heldman, E; Kushnir, M; Levy, R; Pittel, Z; Vogel, Z; Zimlichman, R | 1 |
| Cheng, E; Cline, RT; Fraser, CM; Geoghagen, NS; Lee, NH | 1 |
| De Neef, P; Domenach, V; Vandermeers, A; Vandermeers-Piret, MC; Waelbroeck, M | 1 |
| Drijfhout, WJ; Grol, CJ; Westerink, BH | 1 |
| Mills, J; Reiner, PB | 1 |
| Christopoulos, A; Lanzafame, A; Mitchelson, F | 1 |
| Spindler, KD; Spindler-Barth, M; Wegener, S | 1 |
| Ebihara, T; Saffen, D | 1 |
| Murayama, T; Nomura, Y; Yamada, T | 1 |
| Matthews, MR; Zaidi, ZF | 1 |
| Schimerlik, MI; Sheehan, DM; Vogel, WK | 1 |
| Edwardson, JM; Koenig, JA; Szekeres, PG | 1 |
| Gebauer, M; Versen, B | 1 |
| Dement, WC; Mignot, E; Nishino, S; Reid, MS; Siegel, JM; Tafti, M | 1 |
| Beaucher, J; Harnois, C; Psarropoulou, C | 1 |
| Koizumi, S; Moriyama, Y; Ogura, A; Yamada, H; Yamaguchi, A | 1 |
| Andrade, R; Haj-Dahmane, S | 1 |
| Colecraft, HM; Egamino, JP; Sharma, VK; Sheu, SS | 1 |
| Jaen, JC; Mirzadegan, T; Moreland, D; Schwarz, RD; Spencer, CJ; Tecle, H; Thomas, AJ | 1 |
| Brown, AM; Hunter, AJ; Middlemiss, DN; Watson, JM | 1 |
| Akbulut, H; Akici, A; Karaalp, A; Oktay, S; Ulusoy, NB | 1 |
| Jiang, B; Pappano, AJ; Shen, JB | 1 |
| Ladner, CJ; Lee, JM | 1 |
| Gebauer, M; Schipp, R; Versen, B | 1 |
| Arellano, RO; Garay, E; Miledi, R | 1 |
| Azpiazu, I; Cruzblanca, H; Gautam, N; Li, P; Linder, M; Zhuo, M | 1 |
| Akk, G; Auerbach, A | 1 |
| Malomough, A; Naumenko, N; Nikolsky, E; Urazaev, A; Vyskocil, F | 1 |
| Hamilton, C; Höglund, AU; Lindblom, L | 1 |
| Shapovalova, KB | 1 |
| Fowler, CE; Gunn-Moore, F; Henderson, G; Samways, DS; Yeo, A | 1 |
| Bymaster, FP; Carter, PA; Cohen, ML; Falcone, JF; Felder, CC; Gomeza, J; Shannon, HE; Stengel, PW; Wess, J; Zhang, L | 1 |
| Choppin, A; Eglen, RM | 1 |
| Park, PS; Sum, CS; Wells, JW | 1 |
| de Araujo, EG; dos Santos, AA; Medina, SV; Sholl-Franco, A | 1 |
| Goodhead, LH; Mitchell, SN; Moss, S; Sharott, A | 1 |
| Kawamura, H; Kobayashi, M; Puro, DG; Sakagami, K; Wu, DM | 1 |
| Hosoi, T; Nomura, J; Nomura, Y; Okuma, Y | 1 |
| Borowitz, JL; Gunasekar, PG; Isom, GE; Li, L; Prabhakaran, K; Zhang, L | 1 |
| Bukharaeva, EA; Magazanik, LG; Nikolsky, EE; Samigullin, D; Vyskocil, F | 1 |
| Dong, SJ; Liu, H; Liu, KL; Ruan, JX; Wang, LY; Wang, Y; Zheng, JQ; Zhong, BH | 1 |
| Fernández-López, A; Mostany, R; Paniagua, MA; Pérez, CC; Pilar-Cuéllar, F | 1 |
| Liu, LL; Ruan, JX; Wang, LY; Wang, Y; Zheng, JQ; Zhong, BH | 1 |
| Gamper, N; Hilgemann, DW; Li, Y; Shapiro, MS | 1 |
| Ehlert, FJ; Figueroa, KW; Griffin, MT; Liller, S | 1 |
| Kebig, A; Kostenis, E; Mohr, K; Mohr-Andrä, M | 1 |
| Hancock, J; Hobson, SA; Kelly, E; Marrion, NV; Mason, A; Oldfield, S; Randall, AD; Wynick, D | 1 |
| Christopoulos, A; Kenakin, T; Muniz-Medina, V; Novick, S; Watson, C | 1 |
| Bao, HF; Eaton, AF; Eaton, DC; Helms, MN; Jain, L; Ramosevac, S; Self, J; Takemura, Y | 1 |
| Carlin, J; Jacklin, DL; Mitchnick, KA; O'Hara, M; Stiver, ML; Vicic, N; Winters, BD | 1 |
| Dolejší, E; Doležal, V; El-Fakahany, EE; Jakubík, J; Randáková, A; Rudajev, V; Zimčík, P | 1 |
| Gillet, C; Kuenzel, T; Kurth, S | 1 |
3 review(s) available for carbachol and oxotremorine
| Article | Year |
|---|---|
Pharmacology and second messenger interactions of cloned muscarinic receptors.
Topics: Animals; Atropine; Carbachol; Cell Line; Humans; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic; Recombinant Proteins; Second Messenger Systems; Transfection | 1991 |
Cardioselective muscarinic antagonists.
Topics: Animals; Carbachol; Cardiotonic Agents; Carrier Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Dose-Response Relationship, Drug; Heart; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Pirenzepine; Receptors, Adrenergic; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
The therapeutic use of cholinergic drugs acting on the vegetative nervous system. I - Direct, indirect and mixed agonists.
Topics: Animals; Arecoline; Bethanechol Compounds; Carbachol; Chemical Phenomena; Chemistry; Dimethylphenylpiperazinium Iodide; Ganglia; Kinetics; Lobeline; Neuroeffector Junction; Nicotine; Oxotremorine; Parasympathomimetics; Pilocarpine; Stereoisomerism | 1981 |
275 other study(ies) available for carbachol and oxotremorine
| Article | Year |
|---|---|
Synthesis and cholinergic properties of N-aryl-2-[[[5-[(dimethylamino)methyl]-2-furanyl]methyl]thio]ethylamino analogs of ranitidine.
Topics: Acetylcholine; Animals; Brain; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Synergism; Erythrocytes; Humans; Ileum; Male; Mice; Muscle Contraction; Ranitidine; Rats; Receptors, Muscarinic | 1992 |
Urea and 2-imidazolidone derivatives of the muscarinic agents oxotremorine and N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide.
Topics: Animals; Cerebral Cortex; Guinea Pigs; Ileum; Imidazoles; Molecular Structure; Muscarinic Antagonists; Muscle Contraction; Oxotremorine; Parasympathomimetics; Pyrrolidines; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Structure-Activity Relationship; Urea | 1992 |
Synthesis and cholinergic properties of bis[[(dimethylamino)methyl]furanyl] analogues of ranitidine.
Topics: Animals; Cholinesterase Inhibitors; Furans; Humans; Male; Mice; Parasympathomimetics; Ranitidine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Structure-Activity Relationship | 1992 |
Muscarinic activity of the thiolactone, lactam, lactol, and thiolactol analogues of pilocarpine and a hypothetical model for the binding of agonists to the m1 receptor.
Topics: Animals; Binding, Competitive; Crystallography; Guinea Pigs; Lactams; Male; Mice; Models, Biological; Parasympathomimetics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stereoisomerism; Structure-Activity Relationship; Sulfhydryl Compounds | 1992 |
Muscarinic receptor binding and activation of second messengers by substituted N-methyl-N-[4-(1-azacycloalkyl)-2-butynyl]acetamides.
Topics: Acetamides; Alkynes; Animals; Binding, Competitive; Cell Line; Cell Membrane; Cerebral Cortex; Chemical Phenomena; Chemistry; Female; Fibroblasts; Heterocyclic Compounds; Male; Molecular Structure; Parasympathomimetics; Phosphatidylinositols; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Second Messenger Systems; Transfection | 1991 |
Chemical and biochemical studies of 2-propynylpyrrolidine derivatives. Restricted-rotation analogues of N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide (BM-5).
Topics: Animals; Binding, Competitive; Cerebral Cortex; Chemical Phenomena; Chemistry; Dioxolanes; Guanylyl Imidodiphosphate; Magnetic Resonance Spectroscopy; Male; Molecular Conformation; Molecular Structure; Myocardium; Parasympathomimetics; Pirenzepine; Pyrrolidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stereoisomerism; Structure-Activity Relationship | 1990 |
Tertiary 3- and 4-haloalkylamine analogues of oxotremorine as prodrugs of potent muscarinic agonists.
Topics: Analgesia; Animals; Guinea Pigs; Ileum; In Vitro Techniques; Indicators and Reagents; Kinetics; Magnetic Resonance Spectroscopy; Mice; Muscle Contraction; Oxotremorine; Parasympathomimetics; Pharmaceutical Preparations; Prodrugs; Pyrrolidinones; Saliva; Structure-Activity Relationship; Tremor | 1988 |
5-Methyl-2-pyrrolidone analogues of oxotremorine as selective muscarinic agonists.
Topics: Analgesia; Animals; Body Temperature; Carbachol; Guinea Pigs; In Vitro Techniques; Mice; Muscle, Smooth; Oxotremorine; Parasympathomimetics; Pyrrolidinones; Salivation; Urinary Bladder | 1988 |
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Annulated heterocyclic bioisosteres of norarecoline. Synthesis and molecular pharmacology at five recombinant human muscarinic acetylcholine receptors.
Topics: 3T3 Cells; Animals; Arecoline; Cerebral Cortex; Heterocyclic Compounds; Humans; In Vitro Techniques; Mice; Muscarinic Agonists; Protein Binding; Rats; Receptors, Muscarinic; Recombinant Proteins | 1995 |
The synthesis and biochemical pharmacology of enantiomerically pure methylated oxotremorine derivatives.
Topics: Animals; Binding, Competitive; Cerebral Cortex; Guanylyl Imidodiphosphate; Male; Methylation; N-Methylscopolamine; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Wistar; Receptors, Muscarinic; Scopolamine Derivatives; Stereoisomerism | 1993 |
Synthesis and biological characterization of 1,4,5,6-tetrahydropyrimidine and 2-amino-3,4,5,6-tetrahydropyridine derivatives as selective m1 agonists.
Topics: Animals; Arecoline; Brain; Carbachol; Cell Line; Models, Molecular; Muscarinic Agonists; Phosphatidylinositols; Pyrimidines; Quinuclidinyl Benzilate; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptors, Muscarinic; Structure-Activity Relationship | 1997 |
Design of [R-(Z)]-(+)-alpha-(methoxyimino)-1-azabicyclo[2.2.2]octane-3-acetonitri le (SB 202026), a functionally selective azabicyclic muscarinic M1 agonist incorporating the N-methoxy imidoyl nitrile group as a novel ester bioisostere.
Topics: Alzheimer Disease; Animals; Binding Sites; Blood Pressure; Brain; CHO Cells; Cricetinae; Electroencephalography; Heart Rate; Humans; Imines; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Molecular Structure; Muscarinic Agonists; Protein Binding; Quinuclidines; Rats; Rats, Inbred Strains; Receptor, Muscarinic M1; Receptors, Muscarinic; Recombinant Proteins; Stereoisomerism; Tremor | 1997 |
6beta-Acyloxy(nor)tropanes: affinities for antagonist/agonist binding sites on transfected and native muscarinic receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Binding Sites; Cerebral Cortex; CHO Cells; Cricetinae; Humans; In Vitro Techniques; Muscarinic Agonists; Myocardium; Oxotremorine; Quinuclidinyl Benzilate; Rats; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M3; Receptor, Muscarinic M4; Receptors, Muscarinic; Transfection; Tropanes | 2000 |
Discovering selective agonists of endothelial target for acetylcholine (ETA) via diversity-guided pharmacophore simplification and simulation.
Topics: Acetylcholine; Animals; Aorta; Endothelium, Vascular; Guinea Pigs; Muscarinic Agonists; Rabbits; Rats; Vasodilation | 2004 |
Docking analyses on human muscarinic receptors: unveiling the subtypes peculiarities in agonists binding.
Topics: Binding Sites; Computer Simulation; Humans; Ligands; Muscarinic Agonists; Protein Binding; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptor, Muscarinic M5; Receptors, Muscarinic | 2008 |
The effect of miotics on the intraocular pressure of conscious owl monkeys.
Topics: Anesthesia, Local; Animals; Aotus trivirgatus; Carbachol; Dose-Response Relationship, Drug; Haplorhini; Intraocular Pressure; Male; Miotics; Oxotremorine; Parasympathomimetics; Pilocarpine; Quinuclidines; Spiro Compounds; Succinimides; Tonometry, Ocular | 1976 |
Muscarinic cholinergic binding sites in the developing avian heart.
Topics: Acetylcholine; Animals; Atropine; Benzyl Compounds; Carbachol; Chick Embryo; Heart; Methacholine Compounds; Microsomes; Myocardium; Nicotine; Oxotremorine; Physostigmine; Quaternary Ammonium Compounds; Quinuclidines; Receptors, Cholinergic; Scopolamine; Snake Venoms; Tubocurarine | 1977 |
Occupancy of muscarinic acetylcholine receptors stimulates a guanylate cyclase in neuroblastoma cells.
Topics: Acetylcholine; Atropine; Carbachol; Cell Line; Cell Membrane; Enzyme Activation; Guanylate Cyclase; Kinetics; Neuroblastoma; Oxotremorine; Pilocarpine; Quinuclidines; Receptors, Cholinergic; Receptors, Muscarinic | 1977 |
The effects of cholinomimetic drugs and atropine on ACTH release.
Topics: Acetylcholine; Adrenocorticotropic Hormone; Animals; Atropine; Carbachol; Corticosterone; Drug Implants; Electric Stimulation; Female; Fluoresceins; Hypothalamo-Hypophyseal System; Hypothalamus; Hypothalamus, Anterior; Injections, Intraventricular; Male; Median Eminence; Oxotremorine; Parasympathomimetics; Rats; Stress, Physiological | 1976 |
Drugs affecting the cholinergic system in the intact mammalian eye. I. Evaluation of the miotic activity of acetylcholine-like drugs in the mouse eye.
Topics: Acetylcholine; Animals; Arecoline; Carbachol; Guinea Pigs; Hydrogen-Ion Concentration; Miotics; Oxotremorine; Phencyclidine; Pupil; Quinuclidines | 1975 |
Pharmacological properties of n1-piperonyl-n4-3,7,11-trimethyl-2,6,10-dodecatrienyl-piperazine, a new non-anticholinergic gastric antisecretory agent.
Topics: Animals; Carbachol; Central Nervous System; Depression, Chemical; Dogs; Feeding Behavior; Female; Gastric Juice; Gastric Mucosa; Gastrointestinal Agents; Gastrointestinal Motility; Guinea Pigs; Hemodynamics; Histamine H1 Antagonists; Hydrogen-Ion Concentration; Male; Methacholine Compounds; Mice; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pentagastrin; Peptic Ulcer; Piperazines; Polyenes; Rabbits; Rats; Respiration | 1975 |
Pharmacological study of a cholinergic mechanism within the rat posterior hypothalamic nucleus which mediates a hypertensive response.
Topics: Acetylcholine; Adrenalectomy; Animals; Atropine; Blood Pressure; Carbachol; Cholinergic Fibers; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Heart Rate; Hemicholinium 3; Hypophysectomy; Hypothalamus; Hypothalamus, Posterior; Male; Mecamylamine; Oxotremorine; Phentolamine; Premedication; Rats | 1979 |
GTP-dependent inhibition of cardiac adenylate cyclase by muscarinic cholinergic agonists.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Guanine Nucleotides; Guanosine Triphosphate; In Vitro Techniques; Myocardium; Oxotremorine; Parasympathetic Nervous System; Parasympathomimetics; Rabbits; Time Factors | 1979 |
Effect of cholinergic drugs on the brainstem auditory evoked responses (far-field) in rats.
Topics: Animals; Auditory Pathways; Auditory Perception; Brain Stem; Carbachol; Cholinergic Fibers; Dose-Response Relationship, Drug; Evoked Potentials; Nicotine; Oxotremorine; Parasympathomimetics; Physostigmine; Rats | 1978 |
Effects of cholinergic drugs on auditory evoked responses (CER) of rat cortex.
Topics: Acoustic Stimulation; Animals; Carbachol; Cerebral Cortex; Drug Interactions; Evoked Potentials; Hearing; Nicotine; Oxotremorine; Parasympathomimetics; Physostigmine; Rats; Scopolamine | 1978 |
The effect of cholinergic drugs on [3H]acetylcholine release from slices of rat hippocampus, striatum and cortex.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cerebral Cortex; Corpus Striatum; Drug Interactions; Electric Stimulation; Hippocampus; In Vitro Techniques; Oxotremorine; Parasympathomimetics; Physostigmine; Potassium; Rats; Time Factors | 1977 |
Release of [3H]acetylcholine from rat hippocampal slices: effect of septal lesion and of graded concentrations of muscarnic agonists and antagonists.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzilates; Carbachol; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Hippocampus; In Vitro Techniques; Mecamylamine; Oxotremorine; Pilocarpine; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine; Septum Pellucidum | 1977 |
Decrease in (3H)-quinuclidinyl bezilate binding to the muscarinic cholinergic receptor in the longitudinal muscle of the rat ileum following chronic administration of diisopropylfuorophosphate.
Topics: Acetylcholine; Animals; Binding, Competitive; Carbachol; Cholinesterases; Depression, Chemical; Ileum; In Vitro Techniques; Isoflurophate; Male; Muscle, Smooth; Myocardium; Oxotremorine; Quinuclidines; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Time Factors | 1977 |
[Nigrostiatally induced motor reactions in the rat. II. Cholinergic effect on rotational behavior and posture asymetry].
Topics: Apomorphine; Carbachol; Caudate Nucleus; Hydroxydopamines; Movement Disorders; Oxotremorine; Posture; Receptors, Cholinergic; Receptors, Dopamine | 1976 |
Thermoregulatory changes induced by cholinomimetic substances introduced into the cerebral ventricles of sheep.
Topics: Animals; Atropine; Body Temperature Regulation; Carbachol; Castration; Cerebral Ventricles; Cold Temperature; Hot Temperature; Injections; Male; Nicotine; Oxotremorine; Parasympathomimetics; Pempidine; Physostigmine; Sheep; Shivering; Skin Temperature; Stimulation, Chemical | 1975 |
[Cholinergic effect on the dopamine turnover in the rat corpus striatum].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbachol; Corpus Striatum; Dopamine; Homovanillic Acid; Methyltyrosines; Oxotremorine; Rats | 1975 |
Growth factor-like effects mediated by muscarinic receptors in PC12M1 cells.
Topics: Adenylyl Cyclases; Animals; Calcium; Carbachol; Cell Movement; Cyclic AMP; Cycloheximide; Dactinomycin; DNA; Enzyme Activation; Gene Expression Regulation; Growth Substances; Neurites; Oxotremorine; PC12 Cells; Phosphatidylinositols; Protein Kinase C; Rats; Receptors, Muscarinic; RNA, Messenger | 1992 |
Characterization of muscarinic receptors that mediate contraction of guinea-pig isolated trachea to choline esters: effect of removing epithelium.
Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Dose-Response Relationship, Drug; Epithelium; Guinea Pigs; In Vitro Techniques; Male; Methacholine Chloride; Muscle Contraction; Oxotremorine; Receptors, Muscarinic; Trachea | 1992 |
Enhancement of DNA synthesis in rat thymocytes by stimulating their muscarinic acetylcholine receptors.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cells, Cultured; DNA; Hexamethonium; Hexamethonium Compounds; Isoflurophate; Kinetics; Male; Nicotine; Oxotremorine; Pirenzepine; Rats; Rats, Wistar; Receptors, Muscarinic; Receptors, Nicotinic; Succinylcholine; T-Lymphocytes; Thymidine; Tritium; Tubocurarine | 1992 |
Characterization of muscarinic receptors mediating vasodilation in guinea-pig ileum submucosal arterioles by the use of computer-assisted videomicroscopy.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Arterioles; Benzodiazepinones; Carbachol; Guinea Pigs; Ileum; Methacholine Chloride; Muscarine; Muscarinic Antagonists; Oxotremorine; Parasympatholytics; Parasympathomimetics; Piperidines; Pirenzepine; Prostaglandin Endoperoxides, Synthetic; Receptors, Muscarinic; Vasodilation | 1992 |
Decrement of muscarinic receptor-stimulated low-KM GTPase in striatum and hippocampus from the aged rat.
Topics: Aging; Animals; Blotting, Western; Carbachol; Cell Membrane; Corpus Striatum; GTP Phosphohydrolases; GTP-Binding Proteins; Hippocampus; Kinetics; Macromolecular Substances; Male; Molecular Weight; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1992 |
[Biochemical studies of oxiracetam (CT-848) on cholinergic neurons].
Topics: Acetylcholine; Acetylcholinesterase; Animals; Carbachol; Cerebral Cortex; Choline O-Acetyltransferase; Hippocampus; Male; Oxotremorine; Pyrrolidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Cholinergic | 1992 |
Ganglionic nicotinic receptor agonists exhibit anti-muscarinic effects in guinea-pig olfactory cortical brain slices.
Topics: Alkaloids; Animals; Azocines; Carbachol; Choline; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Ganglionic Stimulants; Guinea Pigs; In Vitro Techniques; Lobeline; Olfactory Bulb; Oxotremorine; Parasympatholytics; Quaternary Ammonium Compounds; Quinolizines | 1992 |
Neuraminidase reduces the number of super-high-affinity [3H]oxotremorine-M binding sites in lung.
Topics: Animals; Carbachol; Clostridium perfringens; Guinea Pigs; In Vitro Techniques; Kinetics; Lung; Male; Membranes; Muscle Contraction; Neuraminidase; Oxotremorine; Receptors, Muscarinic | 1992 |
Effects of muscarinic agonists and depolarizing agents on inositol monophosphate accumulation in the rabbit vagus nerve.
Topics: Acetylcholine; Animals; Arecoline; Cadmium; Calcimycin; Calcium; Carbachol; Dose-Response Relationship, Drug; Hydrolysis; Inositol Phosphates; Lithium; Ouabain; Oxotremorine; Parasympathomimetics; Pirenzepine; Potassium; Rabbits; Receptors, Muscarinic; Time Factors; Vagus Nerve | 1992 |
Central muscarinic receptor subtypes and carrageenin-induced paw oedema in rats.
Topics: Animals; Arecoline; Carbachol; Carrageenan; Cerebellum; Corpus Striatum; Edema; Female; Foot; Gallamine Triethiodide; Inflammation; Male; Oxotremorine; Pirenzepine; Quinuclidines; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1991 |
Effects of dopamine agonists on dopamine secretion from PC12 cells: lack of functional autoreceptor activity.
Topics: Animals; Apomorphine; Carbachol; Dopamine; Dopamine Agents; Haloperidol; Oxotremorine; Phenalenes; Polycyclic Compounds; Potassium; Receptors, Dopamine; Tumor Cells, Cultured | 1991 |
Sialic acid residues as catalysts for M2-muscarinic agonist-receptor interactions.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Cell Membrane; Kinetics; Male; Myocardium; Neuraminidase; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine; Sialic Acids | 1990 |
Pre- and postjunctional muscarinic receptors in canine bronchi.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bethanechol Compounds; Bronchi; Carbachol; Dogs; Electric Stimulation; In Vitro Techniques; Membrane Potentials; Microelectrodes; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Receptors, Muscarinic | 1990 |
Beta-adrenoceptor induced inhibition of muscarinic receptor-stimulated phosphoinositide metabolism is agonist specific in bovine tracheal smooth muscle.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Carbachol; Cattle; Inositol Phosphates; Isoproterenol; Muscle, Smooth; Oxotremorine; Phosphatidylinositols; Propranolol; Receptors, Adrenergic, beta; Receptors, Muscarinic; Trachea | 1991 |
D1 dopamine receptors of NS20Y neuroblastoma cells are functionally similar to rat striatal D1 receptors.
Topics: Benzazepines; Butaclamol; Carbachol; Cell Line; Colforsin; Corpus Striatum; Cyclic AMP; Dopamine; Dopamine Agents; Flupenthixol; Kinetics; Neuroblastoma; Oxotremorine; Phenanthridines; Radioligand Assay; Receptors, Dopamine; Receptors, Dopamine D1; Sulpiride; Tubocurarine | 1991 |
Interactions of agonists with M2 and M4 muscarinic receptor subtypes mediating cyclic AMP inhibition.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Arecoline; Bethanechol; Bethanechol Compounds; Carbachol; Cells, Cultured; CHO Cells; Corpus Striatum; Cricetinae; Cyclic AMP; Kinetics; Male; Muscarine; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1991 |
M3 cholinoceptors and P2y purinoceptors mediating relaxation of arteries in spontaneously hypertensive rats at prehypertensive stages.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arteries; Carbachol; Cholinergic Antagonists; Endothelium, Vascular; Femoral Artery; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Oxotremorine; Parasympatholytics; Purinergic Antagonists; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Cholinergic; Receptors, Purinergic | 1991 |
Inhibitory actions of muscarinic cholinergic receptor agonists on serotonin N-acetyltransferase in bovine pineal explants in culture.
Topics: Animals; Arylamine N-Acetyltransferase; Carbachol; Cattle; Kinetics; Methacholine Chloride; Organ Culture Techniques; Oxotremorine; Parasympathomimetics; Pilocarpine; Pineal Gland; Receptors, Muscarinic | 1991 |
Selective cross-activation/inhibition of second messenger systems and the reduction of age-related deficits in the muscarinic control of dopamine release from perifused rat striata.
Topics: Aging; Animals; Arachidonic Acid; Arachidonic Acids; Biotransformation; Carbachol; Corpus Striatum; Dopamine; In Vitro Techniques; Inosine Triphosphate; Male; Neomycin; Oxotremorine; Perfusion; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Second Messenger Systems; Type C Phospholipases | 1990 |
Partial agonist effects on the interaction between the atrial muscarinic receptor and the inhibitory guanine nucleotide-binding protein in a reconstituted system.
Topics: Animals; Carbachol; GTP Phosphohydrolases; GTP-Binding Proteins; Heart Atria; Kinetics; Oxotremorine; Phosphoric Monoester Hydrolases; Pilocarpine; Receptors, Cholinergic; Structure-Activity Relationship; Swine | 1990 |
Binding characteristics of the muscarinic receptor subtype in rabbit pancreas.
Topics: Animals; Binding, Competitive; Carbachol; Kinetics; Muscarine; Oxotremorine; Pancreas; Parasympathomimetics; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Time Factors; Tritium | 1990 |
Endogenous aspartate release in the rat hippocampus is inhibited by M2 'cardiac' muscarinic receptors.
Topics: Acetylcholine; Animals; Aspartic Acid; Calcium; Carbachol; Chromatography, High Pressure Liquid; Heart; Hippocampus; In Vitro Techniques; Male; Myocardium; Neuromuscular Depolarizing Agents; Oxotremorine; Pirenzepine; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1990 |
Muscarinic suppression of the evoked N-wave by oxotremorine-M recorded in the guinea-pig olfactory cortex slice.
Topics: Action Potentials; Animals; Carbachol; Cerebral Cortex; Diamines; Electric Stimulation; Electroencephalography; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Olfactory Bulb; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pirenzepine; Receptors, Muscarinic | 1990 |
Pretreatment of rats with an organophosphorus insecticide, chlorfenvinphos, protects against subsequent challenge with the same compound.
Topics: Acetylcholinesterase; Animals; Brain; Carbachol; Chlorfenvinphos; Cholinesterases; Dichlorvos; Erythrocytes; Insecticides; Lethal Dose 50; Male; Oxotremorine; Rats; Rats, Inbred F344 | 1990 |
A M3 muscarinic receptor coupled to inositol phosphate formation in the rat cochlea?
Topics: Animals; Carbachol; Cells, Cultured; Cochlea; Inositol; Inositol Phosphates; Lithium; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tritium | 1990 |
Evidence for two modes of Ca2+ entry following muscarinic stimulation of a human salivary epithelial cell line.
Topics: Calcium; Calcium Channel Blockers; Carbachol; Cell Line; Epithelium; Humans; Inositol 1,4,5-Trisphosphate; Membrane Potentials; Oxotremorine; Receptors, Muscarinic; Salivary Glands | 1990 |
Signaling through the muscarinic receptor-adenylate cyclase system of the heart is buffered against GTP over a range of concentrations.
Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Guanosine Triphosphate; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1990 |
Regional differences in the coupling of muscarinic receptors to inositol phospholipid hydrolysis in guinea pig brain.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Atropine; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Brain; Carbachol; Corpus Striatum; Guinea Pigs; Hydrolysis; Oxotremorine; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Time Factors; Tissue Distribution | 1985 |
Augmentation of isoproterenol-stimulated tissue cyclic AMP level by cholinergic agonists in rat parotid gland.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; Atropine; Calcimycin; Calcium; Carbachol; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Norepinephrine; Oxotremorine; Parotid Gland; Phentolamine; Pilocarpine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains | 1985 |
Interactions between the muscarinic receptors, sodium channels, and guanine nucleotide-binding protein(s) in rat atria.
Topics: Acetylcholine; Animals; Batrachotoxins; Benzilates; Carbachol; Dibucaine; Dose-Response Relationship, Drug; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Heart Atria; Ion Channels; Kinetics; Male; Mathematics; Myocardium; Oxotremorine; Piperidines; Rats; Receptors, Muscarinic; Sodium; Veratridine | 1986 |
Positive inotropic effects of acetylcholine and BAY K 8644 in embryonic chick ventricle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Action Potentials; Animals; Calcium; Carbachol; Chick Embryo; Cyclic AMP; Heart; Isoproterenol; Myocardial Contraction; Oxotremorine; Propranolol | 1987 |
Muscarinic receptor-mediated increase in cAMP levels in SK-N-SH human neuroblastoma cells.
Topics: 1-Methyl-3-isobutylxanthine; Adenylate Cyclase Toxin; Carbachol; Cell Line; Colforsin; Cyclic AMP; Humans; Kinetics; Neuroblastoma; Oxotremorine; Pertussis Toxin; Receptors, Muscarinic; Virulence Factors, Bordetella | 1988 |
Pharmacological characterization of muscarinic receptors mediating inhibition of adenylate cyclase activity in the rat retina.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adenylyl Cyclase Inhibitors; Animals; Arecoline; Aziridines; Carbachol; Choline; Colforsin; Cyclic AMP; Male; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Retina | 1988 |
Regulation of histamine release and synthesis in the brain by muscarinic receptors.
Topics: Animals; Brain; Carbachol; Histamine Release; Male; Oxotremorine; Pirenzepine; Potassium; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1989 |
Aging of rat heart myocytes disrupts muscarinic receptor coupling that leads to inhibition of cAMP accumulation and alters the pathway of muscarinic-stimulated phosphoinositide hydrolysis.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Animals, Newborn; Binding, Competitive; Carbachol; Cells, Cultured; Cholera Toxin; Colforsin; Cyclic AMP; Heart; Isoproterenol; Kinetics; Myocardium; Norepinephrine; Oxotremorine; Phosphatidylinositols; Rats; Receptors, Muscarinic; Time Factors | 1989 |
Pharmacological and biochemical characterization of complexes of muscarinic acetylcholine receptor and guanine nucleotide-binding protein.
Topics: Animals; Antibodies; Antigen-Antibody Complex; Atropine; Blotting, Western; Carbachol; Cell Membrane; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Kinetics; Macromolecular Substances; Myocardium; Oxotremorine; Quinuclidinyl Benzilate; Rats; Receptors, Muscarinic; Solubility | 1989 |
Alinidine reverses the descending staircase of isolated rat atria by an antimuscarinic action.
Topics: Animals; Anti-Arrhythmia Agents; Atropine; Carbachol; Clonidine; Female; Guinea Pigs; Heart; In Vitro Techniques; Ipratropium; Isometric Contraction; Male; Oxotremorine; Papillary Muscles; Parasympatholytics; Rats; Rats, Inbred Strains | 1989 |
Sodium-dependent membrane current induced by carbachol in single guinea-pig ventricular myocytes.
Topics: Acetylcholine; Action Potentials; Animals; Barium; Cadmium; Carbachol; Cesium; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Isoproterenol; Membrane Potentials; Ouabain; Oxotremorine; Ryanodine; Sodium; Sodium Channels; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin | 1989 |
Interaction acetylcholine-glutamate in rat hippocampus: involvement of two subtypes of M-2 muscarinic receptors.
Topics: Acetylcholine; Animals; Carbachol; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Male; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Synaptosomes | 1989 |
An embryonic Ca++ mobilizing muscarinic system in the chick embryo heart.
Topics: Animals; Benzofurans; Bethanechol; Bethanechol Compounds; Calcium; Carbachol; Chick Embryo; Chlortetracycline; Female; Fura-2; Heart; Heart Rate, Fetal; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Oxotremorine; Parasympathomimetics; Pilocarpine; Pregnancy; Receptors, Muscarinic | 1989 |
Pirenzepine distinguishes between muscarinic receptor-mediated phosphoinositide breakdown and inhibition of adenylate cyclase.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Adenylyl Cyclase Inhibitors; Animals; Atropine; Benzodiazepinones; Brain; Carbachol; In Vitro Techniques; Inositol; Inositol Phosphates; Male; Myocardium; Oxotremorine; Parotid Gland; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1985 |
The H-L subgroup of guinea-pig cardiac M2 receptors (M2 beta) regulates inositol phosphate formation.
Topics: Acetylcholine; Adenylate Cyclase Toxin; Animals; Carbachol; Guinea Pigs; Hydrolysis; In Vitro Techniques; Inositol Phosphates; Male; Myocardium; Oxotremorine; Pertussis Toxin; Pilocarpine; Receptors, Muscarinic; Virulence Factors, Bordetella | 1989 |
Agonist binding to M1 muscarinic receptors is sensitive to guanine nucleotides.
Topics: Animals; Carbachol; Guanine Nucleotides; Guanylyl Imidodiphosphate; In Vitro Techniques; Indicators and Reagents; Kinetics; Male; Methacholine Compounds; Oxotremorine; Pilocarpine; Pirenzepine; Rabbits; Receptors, Muscarinic; Second Messenger Systems | 1989 |
Muscarinic agonists and guinea-pig perfused tracheal tubes: effects of epithelial removal and route of administration. Smooth Muscle Research Group.
Topics: Animals; Carbachol; Epithelium; Guinea Pigs; In Vitro Techniques; Muscle, Smooth; Oxotremorine; Parasympathomimetics; Trachea | 1989 |
Pharmacologic discrimination between receptor heterogeneity and allosteric interaction: resultant analysis of gallamine and pirenzepine antagonism of muscarinic responses in rat trachea.
Topics: Allosteric Regulation; Animals; Atropine; Binding Sites; Carbachol; Dose-Response Relationship, Drug; Gallamine Triethiodide; In Vitro Techniques; Male; Muscarine; Oxotremorine; Parasympatholytics; Pirenzepine; Rats; Receptors, Muscarinic; Scopolamine; Trachea | 1989 |
Cholinergic receptors in the extraocular rectus muscle of the rabbit.
Topics: Acetylcholine; Animals; Carbachol; Dimethylphenylpiperazinium Iodide; Female; Hexamethonium Compounds; Male; Muscle Contraction; Neuromuscular Blocking Agents; Oculomotor Muscles; Oxotremorine; Rabbits; Receptors, Cholinergic | 1989 |
Presynaptic muscarinic receptors in guinea pig superior cervical ganglion.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Ganglia, Sympathetic; Guinea Pigs; Oxotremorine; Pirenzepine; Receptors, Muscarinic; Synapses | 1989 |
An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Carbachol; Cell Line; Cricetinae; Cyclic AMP; Gene Expression Regulation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Receptors, Muscarinic; Recombinant Proteins; Thionucleotides; Virulence Factors, Bordetella | 1987 |
Lithium blocks a phosphoinositide-mediated cholinergic response in hippocampal slices.
Topics: Adenosine; Carbachol; Enzyme Activation; Hippocampus; Inositol Phosphates; Kinetics; Lithium; Oxotremorine; Phorbol Esters; Phosphatidylinositols; Protein Kinase C; Receptors, Muscarinic; Synapses; Synaptic Transmission | 1988 |
Changes in muscarinic cholinergic-beta adrenergic interactions in isolated rat papillary muscle after 6-hydroxydopamine pretreatment: evidence for compensatory muscarinic supersensitivity.
Topics: Animals; Carbachol; Hydroxydopamines; Isoproterenol; Male; Myocardial Contraction; Norepinephrine; Oxidopamine; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Muscarinic | 1988 |
Cloned M1 muscarinic receptors mediate both adenylate cyclase inhibition and phosphoinositide turnover.
Topics: Acetylcholine; Adenylyl Cyclase Inhibitors; Animals; Atropine; Carbachol; Cell Line; Cloning, Molecular; GTP-Binding Proteins; Oxotremorine; Phosphatidylinositols; Rats; Receptors, Muscarinic; Recombinant Proteins | 1988 |
Calcium-dependent pirenzepine-sensitive muscarinic response in the rat hippocampal slice.
Topics: Animals; Calcium; Carbachol; Hippocampus; In Vitro Techniques; Membrane Potentials; Oxotremorine; Parasympathomimetics; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Pirenzepine; Rats; Receptors, Muscarinic | 1988 |
Muscarinic receptor coupling to inositol phospholipid metabolism in guinea-pig cerebral cortex, parotid gland and ileal smooth muscle.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Guanosine Triphosphate; Guinea Pigs; Ileum; Muscle, Smooth; N-Methylscopolamine; Oxotremorine; Parotid Gland; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
The muscarinic receptor of chick embryo cells: correlation between ligand binding and calcium mobilization.
Topics: Acetylcholine; Animals; Bethanechol; Bethanechol Compounds; Binding, Competitive; Calcium; Carbachol; Chick Embryo; Dose-Response Relationship, Drug; Oxotremorine; Pilocarpine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Spectrometry, Fluorescence | 1985 |
Desensitization of muscarinic acetylcholine receptors: possible relation to receptor heterogeneity and phosphoinositides.
Topics: Acetylcholine; Animals; Benzodiazepinones; Bethanechol; Bethanechol Compounds; Carbachol; Hippocampus; Male; Molecular Conformation; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1986 |
In rat hippocampus, somatostatin 14 and muscarinic receptor ligands modulate an adenylate cyclase belonging to a common domain of the receptor.
Topics: Acetylcholine; Adenylyl Cyclase Inhibitors; Animals; Carbachol; Colforsin; GTP Phosphohydrolases; Hippocampus; Hydrolysis; Oxotremorine; Phosphatidylinositols; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Somatostatin | 1987 |
Both presynaptic nicotinic-like and muscarinic-like autoreceptors regulate acetylcholine release at an identified neuro-neuronal synapse of Aplysia.
Topics: Acetylcholine; Animals; Aplysia; Carbachol; Curare; Hexamethonium; Hexamethonium Compounds; Muscarine; Oxotremorine; Pilocarpine; Receptors, Muscarinic; Receptors, Nicotinic; Synapses | 1988 |
Age-related decrements in the muscarinic enhancement of K+-evoked release of endogenous striatal dopamine: an indicator of altered cholinergic-dopaminergic reciprocal inhibitory control in senescence.
Topics: Aging; Animals; Bethanechol; Bethanechol Compounds; Carbachol; Cholinergic Fibers; Corpus Striatum; Dopamine; Haloperidol; In Vitro Techniques; Nicotine; Oxotremorine; Potassium Chloride; Rats; Rats, Inbred Strains; Receptors, Dopamine; Receptors, Muscarinic | 1988 |
Muscarinic cholinergic receptor subtype on frog esophageal peptic cells: binding and secretion studies.
Topics: Acetylcholine; Animals; Atropine; Bethanechol; Bethanechol Compounds; Carbachol; Esophagus; Imipramine; Kinetics; N-Methylscopolamine; Oxotremorine; Pepsinogens; Pirenzepine; Propranolol; Radioligand Assay; Rana catesbeiana; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Muscarinic agonists and phorbol esters increase tyrosine phosphorylation of a 40-kilodalton protein in hippocampal slices.
Topics: Animals; Carbachol; Hippocampus; In Vitro Techniques; Kinetics; Male; Nerve Tissue Proteins; Oxotremorine; Phorbol Esters; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Tyrosine | 1989 |
Stereoselectivity of muscarinic receptors in vivo and in vitro for oxotremorine analogues. N-[4-(tertiary amino)-2-butynyl]-5-methyl-2-pyrrolidones.
Topics: Abdominal Muscles; Animals; Atropine; Carbachol; Chemical Phenomena; Chemistry; Guinea Pigs; Ileum; Lethal Dose 50; Male; Mice; Muscle Contraction; Oxotremorine; Pyrrolidinones; Rana pipiens; Receptors, Muscarinic; Stereoisomerism; Tremor | 1985 |
Mechanisms of release of atrial natriuretic factor. I. Effect of several agonists and steroids on its release by atrial minces.
Topics: Animals; Arginine Vasopressin; Atrial Natriuretic Factor; Carbachol; Enkephalin, Methionine; Epinephrine; Glucocorticoids; Heart Atria; Isoproterenol; Male; Mineralocorticoids; Oxotremorine; Phenylephrine; Rats; Secretory Rate | 1986 |
Carbachol induces desensitization of cardiac beta-adrenergic receptors through muscarinic M1 receptors.
Topics: Animals; Carbachol; Diglycerides; Dose-Response Relationship, Drug; Enzyme Activation; Gallamine Triethiodide; Heart; Myocardium; Oxotremorine; Propanolamines; Protein Kinase C; Protein Kinases; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Receptors, Muscarinic; Time Factors; Tissue Distribution | 1985 |
Inhibition of ACTH secretion in mouse pituitary tumor cells by activation of muscarinic cholinergic receptors.
Topics: Adenylyl Cyclases; Adrenocorticotropic Hormone; Animals; Carbachol; Cells, Cultured; Cyclic AMP; Isoproterenol; Mice; Oxotremorine; Parasympatholytics; Pertussis Toxin; Pituitary Neoplasms; Receptors, Muscarinic; Scopolamine; Time Factors; Virulence Factors, Bordetella | 1985 |
Potassium ion facilitation of phosphoinositide turnover activation by muscarinic receptor agonists in rat brain.
Topics: Animals; Benzodiazepinones; Carbachol; Dioxolanes; Hippocampus; Histamine; Male; Norepinephrine; Oxotremorine; Phosphatidylinositols; Pirenzepine; Potassium; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1986 |
Muscarinic receptors in mammalian myocardium: effects of atrial and ventricular receptors on phosphatidylinositol metabolism and adenylate cyclase.
Topics: Adenosine Triphosphate; Adenylyl Cyclases; Animals; Atrial Function; Carbachol; Cats; Cyclic AMP; Heart; Inositol; Kinetics; Myocardium; Oxotremorine; Phosphatidylinositols; Quinuclidinyl Benzilate; Receptors, Muscarinic; Ventricular Function | 1986 |
Receptor reserve in the calcium-dependent cyclic AMP response of astrocytoma cells to muscarinic receptor stimulation: demonstration by agonist-induced desensitization, receptor inactivation, and phorbol ester treatment.
Topics: Astrocytoma; Calcium; Carbachol; Cells, Cultured; Cyclic AMP; Inositol Phosphates; Isoproterenol; Oxotremorine; Phorbols; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Tetradecanoylphorbol Acetate | 1986 |
Muscarinic acetylcholine receptor-mediated phosphoinositide turnover in cultured cerebellar granule cells: desensitization by receptor agonists.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Cerebellum; Kinetics; Male; N-Methylscopolamine; Oxotremorine; Phorbol Esters; Phosphatidylinositols; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Virulence Factors, Bordetella | 1987 |
Cholinergic stimulation of arachidonic acid and phosphatidic acid metabolism in C62B glioma cells.
Topics: Acetylcholine; Animals; Arachidonic Acid; Arachidonic Acids; Atropine; Calcimycin; Carbachol; Cell Line; Glioma; Oxotremorine; Parasympathomimetics; Phosphatidic Acids; Pilocarpine; Rats; Time Factors; Tubocurarine | 1986 |
Behavioural and pharmacological characterization of the mouth movements induced by muscarinic agonists in the rat.
Topics: Animals; Arecoline; Brain; Carbachol; Male; Motor Activity; Mouth; Oxotremorine; Parasympathomimetics; Pilocarpine; Rats; Rats, Inbred Strains; Scopolamine | 1986 |
Cholinergic phosphatidylinositol modulation of inhibitory, G protein-linked neurotransmitter actions: electrophysiological studies in rat hippocampus.
Topics: Acetylcholine; Adenosine; Animals; Carbachol; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Male; Membrane Potentials; Models, Neurological; Oxotremorine; Physostigmine; Rats; Rats, Inbred F344; Rats, Inbred Strains; Tetradecanoylphorbol Acetate | 1987 |
Pertussis toxin treatment results in tolerance to the depressant effects of opioid, monoaminergic, and muscarinic agonists on dorsal-horn network responses in mouse spinal cord-ganglion cultures.
Topics: Adenylate Cyclase Toxin; Animals; Carbachol; Drug Tolerance; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Fetus; Ganglia, Spinal; Mice; Morphine; Norepinephrine; Organ Culture Techniques; Oxotremorine; Pertussis Toxin; Serotonin; Spinal Cord; Virulence Factors, Bordetella | 1986 |
Temperature effect on the detection of muscarinic receptor-G protein interactions in ligand binding assays.
Topics: Animals; Brain Stem; Carbachol; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Male; Myocardium; Oxotremorine; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Temperature | 1988 |
Membrane phospholipid polar heads influence the coupling of M2 muscarinic receptors to G proteins.
Topics: Animals; Carbachol; GTP-Binding Proteins; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Membrane Proteins; Myocardium; Oxotremorine; Phospholipids; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Type C Phospholipases | 1988 |
Diethyl ether effects on muscarinic acetylcholine receptor complexes in rat brainstem.
Topics: Animals; Brain Stem; Carbachol; Ether; Ethyl Ethers; GTP-Binding Proteins; Guanosine Triphosphate; Halothane; In Vitro Techniques; Male; Oxotremorine; Rats; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Release of N-[3H]methylscopolamine from isolated guinea pig atria is controlled by diffusion and rebinding.
Topics: Animals; Carbachol; Diffusion; Female; Guinea Pigs; Heart Atria; Male; Membranes; Myocardium; N-Methylscopolamine; Oxotremorine; Receptors, Muscarinic; Scopolamine Derivatives; Time Factors | 1988 |
Carboxyl residue(s) at the ligand-binding site of rat muscarinic receptors.
Topics: Affinity Labels; Animals; Atropine; Binding Sites; Brain Stem; Carbachol; Cerebral Cortex; Heart Atria; In Vitro Techniques; Male; Methylation; Onium Compounds; Oxotremorine; Rats; Receptors, Muscarinic | 1988 |
Central muscarinic cholinergic influences on ethanol sensitivity in long-sleep and short-sleep mice.
Topics: Animals; Body Temperature; Brain; Calcium; Carbachol; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Neurotensin; Oxotremorine; Phosphatidylinositols; Receptors, Muscarinic; Sleep; Species Specificity | 1988 |
Antimuscarinic oxotremorine analogs distinguish high and low affinity agonist states of muscarinic receptors.
Topics: Animals; Binding, Competitive; Carbachol; Cerebral Cortex; Guinea Pigs; Ileum; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Myocardium; Oxotremorine; Parasympatholytics; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Structure-Activity Relationship | 1988 |
Characterization of muscarinic receptors in human pancreatic membranes.
Topics: Carbachol; Cell Membrane; Humans; Oxotremorine; Pancreas; Pilocarpine; Pirenzepine; Receptors, Muscarinic | 1988 |
Brain localization of cholinergic influence on male sex behavior in rats: agonists.
Topics: Animals; Brain; Carbachol; Copulation; Ejaculation; Injections, Intraventricular; Male; Oxotremorine; Parasympathomimetics; Preoptic Area; Rats; Sexual Behavior, Animal | 1988 |
Impaired cardiac muscarinic receptor function in dogs with heart failure.
Topics: Adenylyl Cyclases; Animals; Atropine; Carbachol; Dogs; Female; Guanosine Triphosphate; Heart Failure; Heart Ventricles; Isoproterenol; Male; Methacholine Chloride; Methacholine Compounds; Myocardium; Oxotremorine; Receptors, Muscarinic; Sarcolemma | 1988 |
Characterization of cholinergic muscarinic receptors in the rabbit iris.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Ileum; Iris; Kinetics; Methacholine Chloride; Methacholine Compounds; Microsomes; N-Methylscopolamine; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives | 1988 |
Electrophysiologic responses and adenylate cyclase activities of mouse spinal cord-dorsal root ganglion explants rendered tolerant by chronic exposure to morphine or pertussis toxin.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Carbachol; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Evoked Potentials; Ganglia, Spinal; Mice; Morphine; Norepinephrine; Organ Culture Techniques; Oxotremorine; Pertussis Toxin; Serotonin; Spinal Cord; Virulence Factors, Bordetella | 1987 |
Sialic acid is selectively involved in the interaction of agonists with M2 muscarinic acetylcholine receptors.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Cell Membrane; Kinetics; Male; Myocardium; Neuraminidase; Oxotremorine; Pilocarpine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Sialic Acids | 1988 |
Chemical modification of rat cerebral cortex M1 muscarinic receptors: role of histidyl residues in antagonist and agonist binding.
Topics: Animals; Atropine; Benzilates; Binding Sites; Carbachol; Cerebral Cortex; Diethyl Pyrocarbonate; Histidine; Hydrogen-Ion Concentration; Oxotremorine; Piperidines; Rats; Receptors, Muscarinic; Synaptosomes | 1988 |
Stimulation of phosphatidylinositol (PI) turnover may mediate the muscarinic suppression of the M-current in hippocampal pyramidal cells.
Topics: Animals; Carbachol; Hippocampus; In Vitro Techniques; Inositol Phosphates; Membrane Potentials; Oxotremorine; Phosphatidylinositols; Potassium; Protein Kinase C; Rats; Receptors, Muscarinic | 1988 |
Characterization of agonist and antagonist binding to muscarinic cholinergic receptors solubilized from rat cerebral cortex.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; In Vitro Techniques; Male; Oxotremorine; Pirenzepine; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1988 |
Quantitative effects of some muscarinic agonists on evoked surface-negative field potentials recorded from the guinea-pig olfactory cortex slice.
Topics: Acetylcholine; Animals; Bethanechol Compounds; Carbachol; Cerebral Cortex; Evoked Potentials; Guinea Pigs; In Vitro Techniques; Male; Methacholine Compounds; Oxotremorine; Parasympathomimetics; Temperature | 1988 |
A quantitative study of the effects of some muscarinic antagonists on the guinea-pig olfactory cortex slice.
Topics: Animals; Atropine; Carbachol; Cerebral Cortex; Drug Interactions; Evoked Potentials; Gallamine Triethiodide; Guinea Pigs; In Vitro Techniques; Oxotremorine; Parasympathomimetics; Pirenzepine | 1988 |
The action of pertussis toxin on heart adenylate cyclase and lipolysis in the parametrial adipose tissue of the rat.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Adipose Tissue; Animals; Carbachol; Female; Heart; Isoproterenol; Lipolysis; Myocardium; Oxotremorine; Pertussis Toxin; Phenylisopropyladenosine; Rats; Rats, Inbred Strains; Virulence Factors, Bordetella | 1987 |
Oxygen consumption mediated by M2 muscarinic receptors in rat salivary glands.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Female; Male; Nifedipine; Oxotremorine; Oxygen Consumption; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Salivary Glands; Trihexyphenidyl | 1987 |
Physiological effects of muscarinic vs nicotinic ACh antagonists upon ganglion cell activity in the frog retina.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Bungarotoxins; Carbachol; Electroretinography; Neuromuscular Blocking Agents; Oxotremorine; Physostigmine; Rana esculenta; Receptors, Muscarinic; Receptors, Nicotinic; Retina; Retinal Ganglion Cells; Scopolamine | 1987 |
Dissociation of contraction and muscarinic receptor binding to isolated smooth muscle cells.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Dogs; Kinetics; Methacholine Chloride; Methacholine Compounds; Muscle Contraction; Muscle, Smooth; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Stomach; Temperature | 1986 |
Pertussis toxin blocks depressant effects of opioid, monoaminergic and muscarinic agonists on dorsal-horn network responses in spinal cord-ganglion cultures.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclases; Animals; Carbachol; Electrophysiology; Enkephalin, Leucine; Enkephalin, Leucine-2-Alanine; Ganglia, Spinal; Mice; Morphine; Norepinephrine; Organ Culture Techniques; Oxotremorine; Pertussis Toxin; Serotonin; Spinal Cord; Virulence Factors, Bordetella | 1987 |
Muscarinic and antimuscarinic activity of acetamides related to oxotremorine in the guinea pig urinary bladder.
Topics: Acetamides; Animals; Carbachol; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Oxotremorine; Receptors, Muscarinic; Urinary Bladder | 1987 |
Selectivity of partial agonists related to oxotremorine based on differences in muscarinic receptor reserve between the guinea pig ileum and urinary bladder.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Kinetics; Male; Mathematics; Oxotremorine; Pirenzepine; Pyrrolidines; Receptors, Muscarinic; Spasm; Structure-Activity Relationship; Urinary Bladder | 1987 |
Muscarinic receptor heterogeneity in rat central nervous system. II. Brain receptors labeled by [3H]oxotremorine-M correspond to heterogeneous M2 receptors with very high affinity for agonists.
Topics: Animals; Binding, Competitive; Brain; Carbachol; Cerebral Cortex; Kinetics; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1987 |
Determination of thermodynamic constants for agonist binding to muscarinic receptors from rat cerebral cortex.
Topics: Acetylcholine; Animals; Carbachol; Cerebral Cortex; Kinetics; Male; Oxotremorine; Pilocarpine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Thermodynamics | 1987 |
Genetic influences on tolerance development with chronic oxotremorine infusion.
Topics: Animals; Behavior, Animal; Carbachol; Dose-Response Relationship, Drug; Drug Tolerance; Genotype; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred Strains; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Tissue Distribution | 1987 |
Correlation of agonist-induced phosphorylation of chick heart muscarinic receptors with receptor desensitization.
Topics: Animals; Atropine; Carbachol; Chickens; Dose-Response Relationship, Drug; Guanylyl Imidodiphosphate; Heart; Magnesium; Myocardium; Oxotremorine; Phosphorylation; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1987 |
Choline increases endogenous GABA release in rat hippocampus by a mechanism sensitive to hemicholinium-3.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Choline; gamma-Aminobutyric Acid; Hemicholinium 3; Hippocampus; In Vitro Techniques; Male; Mecamylamine; Oxotremorine; Rats; Rats, Inbred Strains; Synaptosomes | 1987 |
Evidence for involvement of midbrain central gray in cholinergic mediation of female sexual receptivity in rats.
Topics: Animals; Brain Mapping; Carbachol; Cholinergic Fibers; Estradiol; Female; Oxotremorine; Periaqueductal Gray; Posture; Progesterone; Rats; Sexual Behavior, Animal | 1986 |
High-affinity agonist binding to rat brainstem muscarinic receptors is eliminated by low pH.
Topics: Animals; Brain Stem; Carbachol; Guanylyl Imidodiphosphate; Hydrogen-Ion Concentration; Male; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine | 1986 |
Effects of N-ethylmaleimide on muscarinic acetylcholine receptor subtype autoradiography and inositide response in rat brain.
Topics: Animals; Autoradiography; Benzodiazepinones; Brain; Carbachol; Ethylmaleimide; In Vitro Techniques; Male; Oxotremorine; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Cholinergic | 1986 |
Muscarinic receptor coupling to intracellular calcium release in rat pancreatic acinar carcinoma.
Topics: Animals; Binding, Competitive; Calcium; Carbachol; Carcinoma; N-Methylscopolamine; Oxotremorine; Pancreatic Neoplasms; Proteins; Rats; Rats, Inbred F344; Receptors, Muscarinic; Scopolamine Derivatives | 1986 |
Irreversible binding of acetylethylcholine mustard to cardiac cholinergic muscarinic receptors.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cell Membrane; Guanylyl Imidodiphosphate; Heart Rate; Male; Myocardium; N-Methylscopolamine; Oxotremorine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives | 1986 |
Stimulation of phosphatidylinositol metabolism in atrial and ventricular myocytes.
Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Carbachol; Guinea Pigs; Heart Atria; Heart Ventricles; Inositol Phosphates; Lithium; Muscle, Smooth, Vascular; Oxotremorine; Phosphatidylinositols; Time Factors; Vasopressins | 1986 |
Role of lipids in age-related changes in the properties of muscarinic receptors in cultured rat heart myocytes.
Topics: Acetylcholine; Animals; Animals, Newborn; Benzilates; Carbachol; Cells, Cultured; Guanylyl Imidodiphosphate; Kinetics; Liposomes; Myocardium; Oxotremorine; Piperidines; Rats; Receptors, Muscarinic | 1986 |
Stereospecific 3H-QNB binding to human erythrocyte membranes associated with muscarinic cholinergic receptors.
Topics: Adult; Aging; Animals; Atropine; Brain; Carbachol; Erythrocyte Membrane; Female; Guanylyl Imidodiphosphate; Humans; In Vitro Techniques; Male; Middle Aged; Myocardium; Oxotremorine; Quinuclidines; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Stereoisomerism | 1987 |
Pharmacologic characterization and functional role of muscarinic autoreceptors in the rabbit striatum.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Corpus Striatum; Dose-Response Relationship, Drug; Drug Synergism; Haloperidol; Oxotremorine; Physostigmine; Pirenzepine; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine; Time Factors | 1987 |
Characterization of [3H]pirenzepine binding to muscarinic cholinergic receptors solubilized from rat brain.
Topics: Animals; Benzodiazepinones; Binding Sites; Brain; Carbachol; Detergents; In Vitro Techniques; Kinetics; Male; Oxotremorine; Parasympatholytics; Pirenzepine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Solubility; Tritium | 1985 |
Experimental testing of Mackay's model for functional antagonism in the isolated costo-uterus of the rat.
Topics: Animals; Carbachol; Drug Antagonism; Female; Fenoterol; In Vitro Techniques; Kinetics; Male; Models, Biological; Oxotremorine; Phenoxybenzamine; Rats; Rats, Inbred Strains; Uterine Contraction | 1985 |
Different effects of N-ethylmaleimide on M1 and M2 muscarine receptors in rat brain.
Topics: Animals; Binding Sites; Brain; Carbachol; Ethylmaleimide; Male; Oxotremorine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Tissue Distribution | 1985 |
Characterization of muscarinic cholinergic receptors in the crab nervous system.
Topics: Animals; Arecoline; Binding, Competitive; Brachyura; Carbachol; Decamethonium Compounds; Kinetics; Male; Mathematics; Nervous System; Oxotremorine; Pilocarpine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Stereoisomerism; Tissue Distribution; Tubocurarine | 1986 |
Allosteric interactions between muscarinic agonist binding sites and effector sites demonstrated by the use of bisquaternary pyridinium oximes.
Topics: Animals; Brain Stem; Carbachol; Cerebral Cortex; Cobalt; Guanylyl Imidodiphosphate; In Vitro Techniques; Oximes; Oxotremorine; Parasympathomimetics; Pyridinium Compounds; Rats; Receptors, Muscarinic | 1985 |
Muscarinic acetylcholine receptors in the rabbit ciliary body smooth muscle: spare receptors and threshold phenomenon.
Topics: Animals; Arecoline; Atropine; Carbachol; Ciliary Body; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Oxotremorine; Phenoxybenzamine; Pilocarpine; Rabbits; Receptors, Muscarinic | 1985 |
Rat brain and heart muscarinic receptors: modification with tetranitromethane.
Topics: Acetylcholine; Animals; Brain; Brain Stem; Carbachol; Corpus Striatum; Heart Atria; Hippocampus; Methane; Myocardium; Nitrogen; Oxotremorine; Rats; Receptors, Muscarinic; Tetranitromethane | 1985 |
The relationship between muscarinic receptor occupancy and adenylate cyclase inhibition in the rabbit myocardium.
Topics: Adenylyl Cyclase Inhibitors; Animals; Carbachol; Guanosine Triphosphate; In Vitro Techniques; Male; Models, Structural; Myocardium; N-Methylscopolamine; Oxotremorine; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Tritium | 1985 |
Oxotremorine acts as a partial nicotinic agonist on cultured chick myotubes.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Carbachol; Cells, Cultured; Chick Embryo; Microtubules; Muscles; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Nicotinic | 1985 |
Multiple agonist binding sites of muscarinic acetylcholine receptors and their relation to the negative inotropic action of agonists in guinea-pig heart.
Topics: Animals; Binding Sites; Carbachol; Depression, Chemical; Dithionitrobenzoic Acid; Guanylyl Imidodiphosphate; Guinea Pigs; Isoproterenol; Myocardial Contraction; Oxotremorine; Pilocarpine; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1985 |
Central nervous system and autonomic nervous system effects of amantadine and of some standard anti-Parkinson drugs.
Topics: Amantadine; Animals; Antiparkinson Agents; Atropine; Autonomic Nervous System; Body Temperature; Carbachol; Central Nervous System; Dihydroxyphenylalanine; Drug Interactions; Gastrointestinal Motility; Male; Mecamylamine; Mice; Mydriatics; Nicotine; Oxotremorine; Phenothiazines; Pupil; Rats; Trihexyphenidyl | 1973 |
Muscarinic cholinergic binding in rat brain.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Benzilates; Binding Sites; Binding, Competitive; Brain; Brompheniramine; Carbachol; Chlorpheniramine; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Male; Methacholine Compounds; Microsomes; Mitochondria; Oxotremorine; Pilocarpine; Quaternary Ammonium Compounds; Quinuclidines; Rats; Receptors, Cholinergic; Scopolamine; Temperature; Time Factors; Tritium | 1974 |
Muscarinic mediation of the biphasic temperature response to intrahypothalamic injections of carbachol in the cat.
Topics: Animals; Atropa belladonna; Body Temperature Regulation; Carbachol; Cats; Hypothalamus; Male; Mecamylamine; Nicotine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Plants, Medicinal; Plants, Toxic; Receptors, Cholinergic; Species Specificity; Synaptic Transmission | 1974 |
Interrelation between monoaminergic and cholinergic mechanisms in the hypothalamic thermoregulatory centre of rabbits.
Topics: Acetylcholine; Animals; Atropine; Biogenic Amines; Body Temperature Regulation; Carbachol; Cerebral Ventricles; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Female; Hypothalamus; Injections; Male; Norepinephrine; Oxotremorine; Parasympathetic Nervous System; Phenoxybenzamine; Physostigmine; Pilocarpine; Propranolol; Rabbits; Receptors, Cholinergic; Serotonin; Time Factors; Tubocurarine | 1974 |
Temperature reducing effect of oxotremorine in the rat and the mouse.
Topics: Acetylcholine; Amyl Nitrite; Animals; Atropine; Atropine Derivatives; Blood Pressure; Body Temperature; Carbachol; Chlorpromazine; Dopamine; Dose-Response Relationship, Drug; Epinephrine; Ethanol; Female; Isoproterenol; Male; Mice; Norepinephrine; Oxotremorine; Oxygen Consumption; Temperature; Tremorine; Urethane; Vasopressins | 1973 |
Proceedings: The nature of the thermoregulatory sensitivity to cholinomimetic drugs in the cerebral ventricles of sheep.
Topics: Acetylcholine; Animals; Atropine; Body Temperature Regulation; Carbachol; Cerebral Ventricles; Nicotine; Oxotremorine; Parasympathomimetics; Physostigmine; Sheep; Shivering; Temperature | 1974 |
Effects of several muscarinic agonists on cardiac performance and the release of noradrenaline from sympathetic nerves of the perfused rabbit heart.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Carbamates; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Heart; Heart Rate; Hexamethonium Compounds; In Vitro Techniques; Male; Methacholine Compounds; Norepinephrine; Oxotremorine; Parasympathomimetics; Perfusion; Pilocarpine; Quaternary Ammonium Compounds; Rabbits; Sympathetic Nervous System | 1972 |
The character of the muscarinic receptors in different regions of the rat brain.
Topics: Animals; Binding Sites; Brain; Carbachol; Mathematics; Oxotremorine; Propylbenzilylcholine Mustard; Rats; Receptors, Cholinergic; Receptors, Muscarinic | 1980 |
Influence of cholinomimetics and cholinolytics on vestibular compensation.
Topics: Animals; Arecoline; Bethanechol; Bethanechol Compounds; Carbachol; Ear, Inner; Methacholine Chloride; Methacholine Compounds; Muscarine; Nicotine; Oxotremorine; Rana temporaria; Vestibule, Labyrinth | 1981 |
Effects of neurotransmitters on calcium efflux from cultured glioma cells.
Topics: Astrocytoma; Atropine; Calcium; Calcium Radioisotopes; Carbachol; Cells, Cultured; Cyclic AMP; Cyclic GMP; Glutamates; Glutamic Acid; Glycine; Hexamethonium; Hexamethonium Compounds; Humans; Neoplasms, Experimental; Nicotine; Norepinephrine; Oxotremorine; Prostaglandins E; Time Factors | 1981 |
Muscarinic cholinergic stimulation of somatostatin secretion from long term dispersed cell cultures of fetal rat hypothalamus: inhibition by gamma-aminobutyric acid and serotonin.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Female; gamma-Aminobutyric Acid; Hexamethonium Compounds; Hypothalamus; Oxotremorine; Pregnancy; Rats; Rats, Inbred Strains; Receptors, Cholinergic; Receptors, Muscarinic; Serotonin; Somatostatin; Tetrodotoxin | 1983 |
Effects of acetylcholine on sodium-dependent high-affinity glutamate transport in rat striatal homogenates.
Topics: Acetylcholine; Animals; Atropine; Biological Transport; Carbachol; Corpus Striatum; Glutamates; Glutamic Acid; Kinetics; Male; Nicotine; Oxotremorine; Rats; Rats, Inbred Strains; Sodium | 1983 |
Increase in muscarinic acetylcholine receptors in mouse intestine by hexamethonium treatment.
Topics: Animals; Brain; Carbachol; Female; Hexamethonium; Hexamethonium Compounds; Ileum; Intestinal Mucosa; Male; Mice; Muscle Contraction; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic; Rectum | 1983 |
Affinity, efficacy, and stereoselectivity of oxotremorine analogues for muscarinic receptors in the isolated guinea pig ileum.
Topics: Animals; Atropine; Carbachol; Dibenzylchlorethamine; Dose-Response Relationship, Drug; Guinea Pigs; Hexamethonium; Hexamethonium Compounds; Ileum; Isomerism; Male; Oxotremorine; Parasympatholytics; Receptors, Cholinergic; Receptors, Muscarinic; Structure-Activity Relationship | 1983 |
Muscarinic acetylcholine receptor activation causes inhibition of cyclic AMP accumulation, prolactin and growth hormone secretion in GH3 rat anterior pituitary tumour cells.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Carbachol; Cell Line; Cyclic AMP; Growth Hormone; Kinetics; Oxotremorine; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Rats; Receptors, Muscarinic; Vasoactive Intestinal Peptide | 1984 |
A comparison of the stimulant activities of oxotremorine analogues on the frog rectus abdominis and the guinea pig ileum.
Topics: Abdominal Muscles; Animals; Carbachol; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Oxotremorine; Rana pipiens; Receptors, Muscarinic; Receptors, Nicotinic; Structure-Activity Relationship | 1984 |
Quantitative receptor autoradiography: application to the characterization of multiple receptor subtypes.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Atropine; Autoradiography; Benzodiazepinones; Binding, Competitive; Brain; Carbachol; Hippocampus; Indoles; Oxotremorine; Pindolol; Pirenzepine; Rats; Receptors, Muscarinic; Receptors, Serotonin; Superior Colliculi; Tetrahydronaphthalenes | 1984 |
Comparative properties of the in ovo and in vitro differentiation of the muscarinic cholinergic receptor in embryonic heart cells.
Topics: Acetylcholine; Animals; Carbachol; Cells, Cultured; Chick Embryo; Cyclic GMP; Heart; Heart Rate; Myocardial Contraction; Myocardium; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic | 1980 |
Characteristics of histamine release evoked by acetylcholine in isolated rat mast cells.
Topics: Acetylcholine; Animals; Atropine; Bucladesine; Carbachol; Choline; Epinephrine; Histamine Release; Hydrogen-Ion Concentration; In Vitro Techniques; Male; Mast Cells; Oxotremorine; Rats; Secretory Rate; Sodium | 1980 |
Muscarinic-dopaminergic synergism on retinal cyclic AMP formation.
Topics: Animals; Atropine; Carbachol; Cyclic AMP; Female; Oxotremorine; Rats; Receptors, Cholinergic; Receptors, Dopamine; Receptors, Muscarinic; Retina | 1981 |
Muscarinic cholinergic receptor-mediated control of cyclic AMP metabolism. Agonist-induced changes in nucleotide synthesis and degradation.
Topics: Alprostadil; Astrocytoma; Carbachol; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Isoproterenol; Oxotremorine; Prostaglandins E; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic | 1983 |
Agonists differentiate muscarinic receptors that inhibit cyclic AMP formation from those that stimulate phosphoinositide metabolism.
Topics: Animals; Carbachol; Chick Embryo; Cyclic AMP; In Vitro Techniques; Kinetics; Myocardium; Oxotremorine; Phosphatidylinositols; Quinuclidinyl Benzilate; Receptors, Muscarinic | 1984 |
The conversion of 2-chloroalkylamine analogues of oxotremorine to aziridinium ions and their interactions with muscarinic receptors in the guinea pig ileum.
Topics: Alkylation; Animals; Aziridines; Azirines; Binding, Competitive; Carbachol; Chlorides; Guinea Pigs; Hydrolysis; Ileum; Indicators and Reagents; Kinetics; Muscle Contraction; Oxotremorine; Pyrrolidinones; Quinuclidinyl Benzilate; Rana pipiens; Receptors, Muscarinic | 1984 |
Effects of acute ketotic and non-ketotic diabetes on the myocardial muscarinic receptors.
Topics: Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; Carbachol; Computers; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Guanylyl Imidodiphosphate; Insulin; Male; Models, Biological; Myocardium; Oxotremorine; Quinuclidinyl Benzilate; Rats; Rats, Inbred Strains; Receptors, Muscarinic | 1984 |
Pharmacological and anatomical aspects of cholinergic activation of female sexual behavior.
Topics: Animals; Atropine; Carbachol; Castration; Dose-Response Relationship, Drug; Female; Injections, Intraventricular; Oxotremorine; Preoptic Area; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Scopolamine; Sexual Behavior, Animal; Ventromedial Hypothalamic Nucleus | 1984 |
Evidence from phospholipid metabolism changes for muscarinic cholinergic receptors on rat anterior pituitary cells.
Topics: Animals; Carbachol; Culture Techniques; Male; Membrane Lipids; Oxotremorine; Phospholipids; Pilocarpine; Pituitary Gland, Anterior; Rats; Receptors, Muscarinic | 1983 |
Effect of pH on binding of agonists and antagonists to rat heart muscarinic receptors.
Topics: Animals; Atropine; Carbachol; Cell Membrane; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Models, Biological; Myocardium; Oxotremorine; Parasympathomimetics; Pilocarpine; Rats; Receptors, Muscarinic; Scopolamine; Solanaceous Alkaloids | 1983 |
The effects of p-chloromercuribenzoate on muscarinic receptors in the cerebral cortex.
Topics: Animals; Carbachol; Cerebral Cortex; Chloromercuribenzoates; Drug Interactions; In Vitro Techniques; Oxotremorine; p-Chloromercuribenzoic Acid; Propylbenzilylcholine Mustard; Rats; Receptors, Muscarinic; Tritium | 1983 |
Determination of dissociation constants and relative efficacies of oxotremorine analogs at muscarinic receptors in the guinea-pig ileum by pharmacological procedures.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Ileum; Kinetics; Mathematics; Oxotremorine; Propylbenzilylcholine Mustard; Receptors, Muscarinic; Structure-Activity Relationship | 1984 |
Presynaptic muscarinic modulation of nicotinic excitation in the rat neostriatum.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Corpus Striatum; Electric Stimulation; Evoked Potentials; In Vitro Techniques; Muscarine; Nicotine; Oxotremorine; Potassium; Rats; Receptors, Muscarinic; Receptors, Nicotinic | 1984 |
Partial agonist activity of oxotremorine at muscarinic acetylcholine receptors in the embryonic chick heart.
Topics: Animals; Carbachol; Chick Embryo; Heart; Heart Rate; Oxotremorine; Receptors, Muscarinic | 1984 |
The time course of muscarinic depolarization of guinea-pig myenteric neurones.
Topics: Acetylcholine; Animals; Barium; Carbachol; Guinea Pigs; In Vitro Techniques; Methacholine Compounds; Myenteric Plexus; Neostigmine; Neurons; Oxotremorine; Receptors, Muscarinic; Scopolamine; Temperature; Time Factors | 1984 |
Differential regulation of muscarinic and nicotinic receptors by cholinergic stimulation in cultured avian retina cells.
Topics: Animals; Atropine; Carbachol; Cells, Cultured; Chick Embryo; N-Methylscopolamine; Neurons; Nicotine; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic; Receptors, Nicotinic; Retina; Scopolamine Derivatives; Tubocurarine | 1983 |
Modification by hexamethonium of the muscarinic receptors blocking activity of pancuronium and homatropine in isolated tissues of the guinea-pig.
Topics: Animals; Carbachol; Female; Guinea Pigs; Heart; Hexamethonium Compounds; Ileum; Male; Mecamylamine; Oxotremorine; Pancuronium; Receptors, Cholinergic; Receptors, Muscarinic; Tropanes | 1982 |
Isolated rat gastric parietal cells: cholinergic response and pharmacology.
Topics: Acetylcholine; Aminopyrine; Animals; Atropine; Biological Transport; Carbachol; Dose-Response Relationship, Drug; Gastric Mucosa; In Vitro Techniques; Methacholine Chloride; Methacholine Compounds; Oxotremorine; Rats | 1981 |
The effect of amitriptyline, mianserin, and viloxazine at pre- and post-junctional muscarinic receptors in guinea-pig ileal longitudinal muscle.
Topics: Acetylcholine; Amitriptyline; Animals; Antidepressive Agents; Atropine; Carbachol; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mianserin; Muscle, Smooth; Oxotremorine; Receptors, Cholinergic; Receptors, Muscarinic; Viloxazine | 1982 |
In vivo regulation of muscarinic cholinergic receptors in embryonic chick brain.
Topics: Animals; Binding, Competitive; Brain; Carbachol; Chick Embryo; Kinetics; Membranes; Oxotremorine; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic; Time Factors | 1982 |
Do cholinomimetics specifically antagonize rotational behavior?
Topics: Animals; Carbachol; Caudate Nucleus; Dopamine; Female; Humans; Injections; Oxotremorine; Parasympathomimetics; Posture; Rats; Rats, Inbred Strains; Rotation; Stereotyped Behavior; Substantia Nigra | 1981 |
Effect of some cholinergic drugs on the conditioned pole jump response in rats.
Topics: Animals; Avoidance Learning; Carbachol; Conditioning, Psychological; Female; Male; Nicotine; Oxotremorine; Parasympathomimetics; Physostigmine; Rats; Time Factors | 1981 |
Kinetic studies on muscarinic antagonist-agonist competition.
Topics: Animals; Atropine; Benzilates; Binding, Competitive; Carbachol; Intestine, Small; Kinetics; Male; Muscle, Smooth; Oxotremorine; Parasympatholytics; Piperidines; Rats; Receptors, Cholinergic; Receptors, Muscarinic | 1980 |
Regulation of muscarinic acetylcholine receptor concentration in cloned neuroblastoma cells.
Topics: Acetylcholine; Animals; Arecoline; Carbachol; Cell Line; Clone Cells; Dose-Response Relationship, Drug; Kinetics; Mice; Neuroblastoma; Oxotremorine; Pilocarpine; Quinuclidinyl Benzilate; Receptors, Cholinergic; Receptors, Muscarinic | 1980 |
Analysis of regional variations in the affinities of muscarinic agonists in the rat brain.
Topics: Animals; Atropine; Binding, Competitive; Brain; Carbachol; Male; Oxotremorine; Pilocarpine; Quinuclidinyl Benzilate; Rats; Receptors, Cholinergic; Receptors, Muscarinic | 1980 |
Studies on the putative anticholinergic effects of desmethylimipramine.
Topics: Animals; Atropine; Blepharoptosis; Carbachol; Defecation; Desipramine; Gastric Juice; Male; Mice; Mydriatics; Oxotremorine; Parasympatholytics; Rats; Salivation | 1980 |
Muscarinic receptor subsensitivity in the longitudinal muscle of the rat ileum following chronic anticholinesterase treatment with diisopropylfluorophosphate.
Topics: Acetylcholine; Animals; Carbachol; Cholinesterases; Drug Tolerance; Ileum; In Vitro Techniques; Isoflurophate; Kinetics; Male; Muscle, Smooth; Oxotremorine; Rats; Receptors, Cholinergic; Receptors, Muscarinic; Time Factors | 1980 |
Muscarinic cholinergic stimulation of the nitric oxide-cyclic GMP signaling system in cultured rat sensory neurons.
Topics: Acetylcholine; Amino Acid Oxidoreductases; Animals; Arginine; Atropine; Capsaicin; Carbachol; Cells, Cultured; Cyclic GMP; Embryo, Mammalian; Ganglia, Spinal; Guanylate Cyclase; Methacholine Chloride; Methylene Blue; Neurons, Afferent; Nicotine; Nitric Oxide; Nitric Oxide Synthase; Nitroprusside; omega-N-Methylarginine; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction | 1994 |
Expression of muscarinic M3-receptors coupled to inositol phospholipid hydrolysis in human detrusor cultured smooth muscle cells.
Topics: Carbachol; Cells, Cultured; Diamines; Humans; Hydrolysis; Inositol Phosphates; Methacholine Chloride; Muscarinic Agonists; Muscle, Smooth; Oxotremorine; Phosphatidylinositols; Pilocarpine; Pirenzepine; Receptors, Muscarinic; Urinary Bladder | 1995 |
Galanin stimulates striatal acetylcholine release via a mechanism unrelated to cholinergic receptor stimulation.
Topics: Acetylcholine; Animals; Bupivacaine; Carbachol; Chromatography, High Pressure Liquid; Corpus Striatum; Galanin; Injections, Intraperitoneal; Male; Neuropeptides; Oxotremorine; Peptides; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, Cholinergic; Receptors, Galanin; Receptors, Gastrointestinal Hormone; Scopolamine; Substance P | 1993 |
The effect of muscarinic agonists and selective receptor subtype antagonists on the contractile response of the isolated rhesus monkey ciliary muscle.
Topics: Animals; Carbachol; Ciliary Body; Dose-Response Relationship, Drug; In Vitro Techniques; Macaca mulatta; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Piperidines; Pirenzepine; Quinuclidines | 1994 |
Neurotransmitter and neuropeptide modulation of high affinity choline uptake in Limulus brain.
Topics: Animals; Atropine; Brain; Carbachol; Choline; FMRFamide; Horseshoe Crabs; Neuropeptides; Neurotransmitter Agents; Octopamine; Oligopeptides; Oxotremorine; Pirenzepine; Potassium; Serotonin; Tubocurarine | 1995 |
Attenuation of muscarinic receptor-G-protein interaction in Alzheimer disease.
Topics: Aged; Aged, 80 and over; Alzheimer Disease; Carbachol; Cerebral Cortex; Choline O-Acetyltransferase; Female; Frontal Lobe; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Male; Middle Aged; Oxotremorine; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Pirenzepine; Receptors, Muscarinic; Reference Values; Regression Analysis; Synaptic Membranes; Synaptosomes | 1995 |
Dissociation of striatal GTPase and dopamine release responses to muscarinic cholinergic agonists in F344 rats: influence of age and dietary manipulation.
Topics: Aging; Animals; Carbachol; Cholesterol; Cholinergic Agents; Corpus Striatum; Diet; Dopamine; GTP Phosphohydrolases; Male; Oxotremorine; Phospholipids; Potassium Chloride; Rats; Rats, Inbred F344; Synaptosomes | 1995 |
The mechanism of muscarinic agonist-stimulated inositol phosphate formation in permeabilized ileal smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Drug Synergism; GTP-Binding Proteins; Guanylyl Imidodiphosphate; Guinea Pigs; Hydrolysis; Ileum; In Vitro Techniques; Male; Muscarinic Agonists; Muscle, Smooth; Oxotremorine; Phosphatidylinositols; Pilocarpine; Substrate Specificity; Time Factors; Type C Phospholipases | 1994 |
Muscarinic inhibition of cardiac norepinephrine and neuropeptide Y release during ischemia and reperfusion.
Topics: Animals; Atropine; Carbachol; Electric Stimulation; Guinea Pigs; Heart; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Neuropeptide Y; Norepinephrine; Oxotremorine; Parasympatholytics; Pirenzepine; Receptors, Muscarinic | 1994 |
Enhanced MPTP neurotoxicity after treatment with isoflurophate or cholinergic agonists.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Carbachol; Corpus Striatum; Dopamine; Drug Synergism; Isoflurophate; Male; Mice; MPTP Poisoning; Nicotine; Oxotremorine; Parasympathomimetics; Receptors, Cholinergic; Tyrosine 3-Monooxygenase | 1994 |
A comparison between muscarinic receptor occupancy, inositol 1,4,5-trisphosphate accumulation and Ca2+ mobilization in permeabilized SH-SY5Y neuroblastoma cells.
Topics: Arecoline; Brain Neoplasms; Calcium; Calcium Radioisotopes; Carbachol; Guanine Nucleotides; Humans; Inositol 1,4,5-Trisphosphate; Kinetics; Ligands; Neuroblastoma; Oxotremorine; Patch-Clamp Techniques; Receptors, Muscarinic; Signal Transduction; Tumor Cells, Cultured | 1994 |
Acetylcholine receptor agonists stimulate [3H]taurine release from rat sympathetic ganglia.
Topics: Amino Acids; Animals; Atropine; Carbachol; Cholinergic Agonists; Chromatography, High Pressure Liquid; Dimethylphenylpiperazinium Iodide; Dose-Response Relationship, Drug; Drug Interactions; Fluorometry; Hexamethonium; Male; Microscopy; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Rats; Rats, Wistar; Regression Analysis; Superior Cervical Ganglion; Taurine | 1994 |
Reductions of 56Fe heavy-particle irradiation-induced deficits in striatal muscarinic receptor sensitivity by selective cross-activation/inhibition of second-messenger systems.
Topics: Analysis of Variance; Animals; Arachidonic Acid; Arginine Vasopressin; Carbachol; Corpus Striatum; Dopamine; In Vitro Techniques; Iron Radioisotopes; Male; Oxotremorine; Potassium Chloride; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Second Messenger Systems; Whole-Body Irradiation | 1994 |
Sigma receptors and signal transduction: negative modulation of signaling through phosphoinositide-linked receptor systems.
Topics: Animals; Carbachol; Male; Oxotremorine; Pentazocine; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Receptors, sigma; Signal Transduction | 1993 |
Chromodacryorrhea in rats: absence following soman poisoning.
Topics: Acetylcholinesterase; Animals; Brain; Carbachol; Carboxylesterase; Carboxylic Ester Hydrolases; Harderian Gland; Lacrimal Apparatus Diseases; Male; Nicotine; Oxotremorine; Parasympathomimetics; Physostigmine; Pilocarpine; Rats; Rats, Sprague-Dawley; Soman | 1994 |
Characteristics and regulation of a muscarinically activated K current in HSG-PA cells.
Topics: Calcium; Carbachol; Cell Line; Electrophysiology; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Oxotremorine; Parasympathomimetics; Potassium; Potassium Channel Blockers; Salivary Glands; Signal Transduction; Tetraethylammonium; Tetraethylammonium Compounds | 1994 |
Muscarinic potentiation of excitatory amino acid-evoked dopamine release in mesencephalic cells: specificity for the NMDA response and role of intracellular messengers.
Topics: Alkaloids; Animals; Carbachol; Cells, Cultured; Cyclic AMP-Dependent Protein Kinases; Dopamine; Drug Synergism; Fetus; Isoquinolines; Kainic Acid; Kinetics; Mesencephalon; N-Methylaspartate; Neurons; Oxotremorine; Protein Kinase C; Quisqualic Acid; Rats; Receptors, Muscarinic; Receptors, N-Methyl-D-Aspartate; Second Messenger Systems; Staurosporine | 1993 |
Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes.
Topics: Animals; Atropine; Carbachol; Dose-Response Relationship, Drug; Fluorescence Polarization; Lymphocytes; Male; Membrane Fluidity; Oxotremorine; Pilocarpine; Rats; Rats, Sprague-Dawley; Scopolamine; Spleen | 1993 |
Studies of muscarinic receptor reserve linked to phosphoinositide hydrolysis in parotid gland and cerebral cortex.
Topics: Animals; Carbachol; Cerebral Cortex; Choline; Guinea Pigs; Hydrolysis; In Vitro Techniques; Kinetics; N-Methylscopolamine; Oxotremorine; Parasympathomimetics; Parotid Gland; Phosphatidylinositols; Pirenzepine; Receptors, Muscarinic; Scopolamine Derivatives | 1993 |
Multiple second-messenger pathways mediate agonist regulation of muscarinic receptor mRNA expression.
Topics: Adenylate Cyclase Toxin; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Carbachol; Chick Embryo; Cyclic AMP; Enzyme Activation; Gene Expression Regulation; Heart; Myocardium; Oxotremorine; Pertussis Toxin; Pilocarpine; Receptors, Muscarinic; RNA, Messenger; Second Messenger Systems; Type C Phospholipases; Virulence Factors, Bordetella | 1993 |
Muscarinic M3 receptors mediate total inositol phosphates accumulation in murine HSDM1C1 fibrosarcoma cells.
Topics: Animals; Binding, Competitive; Carbachol; Dioxolanes; Fibrosarcoma; Inositol Phosphates; Mice; Muscarine; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Parasympathomimetics; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Scopolamine Derivatives; Tumor Cells, Cultured | 1993 |
Differences between rat dorsal and ventral hippocampus in muscarinic receptor agonist binding and interaction with phospholipase C.
Topics: Alkaloids; Animals; Carbachol; Furans; Guanylyl Imidodiphosphate; Hippocampus; Male; Membranes; Mitochondria; N-Methylscopolamine; Naphthalenes; Oxotremorine; Parasympatholytics; Parasympathomimetics; Phosphatidylinositols; Piperidines; Pirenzepine; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Scopolamine Derivatives; Synaptosomes; Type C Phospholipases | 1993 |
Muscarinic receptor regulation and 2nd messenger responses in rat neocortex cultures.
Topics: Animals; Binding, Competitive; Carbachol; Cells, Cultured; Cerebral Cortex; Down-Regulation; Oxotremorine; Parasympatholytics; Piperidines; Pirenzepine; Rats; Receptors, Muscarinic; Second Messenger Systems | 1993 |
Muscarinic m2 receptors in cerebellar granule cell cultures from rat: mechanism of short-term desensitization.
Topics: Adenylyl Cyclase Inhibitors; Animals; beta-Adrenergic Receptor Kinases; Carbachol; Cells, Cultured; Cerebellum; Cyclic AMP-Dependent Protein Kinases; Muscarine; Neurons; Oxotremorine; Protein Kinases; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 1993 |
Affinity ligands and related agents for brain muscarinic and nicotinic cholinergic receptors.
Topics: Affinity Labels; Animals; Brain; Carbachol; Choline; Kinetics; Ligands; Mice; Naloxone; Nicotine; Oxotremorine; Procaine; Quinuclidinyl Benzilate; Receptors, Muscarinic; Receptors, Nicotinic; Seizures; Tritium | 1993 |
Muscarinic cholinergic receptors in brain and atrial membranes of adult brook trout (Salvelinus fontinalis) measured by radioligand binding techniques.
Topics: Animals; Atropine; Binding, Competitive; Brain Chemistry; Carbachol; Heart Atria; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Pirenzepine; Radioligand Assay; Receptors, Muscarinic; Scopolamine; Scopolamine Derivatives; Trout | 1995 |
Pharmacological basis for functional selectivity of partial muscarinic receptor agonists.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adenylyl Cyclase Inhibitors; Animals; Binding, Competitive; Carbachol; CHO Cells; Cricetinae; Humans; Hydrolysis; Muscarinic Agonists; Oxotremorine; Phosphatidylinositols; Receptors, Muscarinic; Signal Transduction | 1996 |
Alanine scanning mutagenesis of conserved arginine/lysine-arginine/lysine-X-X-arginine/lysine G protein-activating motifs on m1 muscarinic acetylcholine receptors.
Topics: Alanine; Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Carbachol; Cell Membrane; CHO Cells; Conserved Sequence; Cricetinae; DNA Primers; GTP-Binding Proteins; Guanosine Triphosphate; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Methylscopolamine; Oxotremorine; Protein Structure, Secondary; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Receptors, Muscarinic; Recombinant Proteins; Scopolamine Derivatives; Second Messenger Systems; Transfection | 1996 |
Binding of the labelled muscarinic toxin 125I-MT1 to rat brain muscarinic M1 receptors.
Topics: Alkaloids; Animals; Atropine; Binding, Competitive; Brain; Carbachol; Elapid Venoms; Furans; Gallamine Triethiodide; In Vitro Techniques; Iodine Radioisotopes; Isotope Labeling; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; Naphthalenes; Oxotremorine; Parasympatholytics; Pilocarpine; Piperidines; Pirenzepine; Protein Binding; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Synaptic Membranes; Tubocurarine | 1996 |
Parasympathetic inhibition of pineal indole metabolism by prejunctional modulation of noradrenaline release.
Topics: Animals; Carbachol; Cholinergic Agonists; Male; Melatonin; Microdialysis; Nicotine; Norepinephrine; Oxotremorine; Pineal Gland; Rats; Serotonin; Tryptamines | 1996 |
Phorbol esters but not the cholinergic agonists oxotremorine-M and carbachol increase release of the amyloid precursor protein in cultured rat cortical neurons.
Topics: Amyloid beta-Protein Precursor; Animals; Atropine; Carbachol; Cells, Cultured; Cerebral Cortex; Embryo, Mammalian; Muscarinic Agonists; Neurons; Oxotremorine; Phorbol 12,13-Dibutyrate; Phosphatidylinositols; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Signal Transduction; Tetradecanoylphorbol Acetate | 1996 |
Interactions of agonists with an allosteric antagonist at muscarinic acetylcholine M2 receptors.
Topics: Acetylcholine; Animals; Binding, Competitive; Bis-Trimethylammonium Compounds; Buffers; Carbachol; Dioxolanes; Drug Interactions; Female; Guinea Pigs; In Vitro Techniques; Isoindoles; Kinetics; Male; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Receptor, Muscarinic M2; Receptors, Muscarinic | 1996 |
A muscarinic acetylcholine receptor, present in the epithelial cell line from Chironomus tentans.
Topics: Animals; Atropine; Binding Sites; Binding, Competitive; Blotting, Western; Carbachol; Cell Line; Chironomidae; Ecdysterone; Epithelium; Ethylmaleimide; Guanylyl Imidodiphosphate; Kinetics; Oxotremorine; Pirenzepine; Quinuclidinyl Benzilate; Receptors, Cholinergic | 1996 |
Muscarinic acetylcholine receptor-mediated induction of zif268 mRNA in PC12D cells requires protein kinase C and the influx of extracellular calcium.
Topics: Animals; Calcium; Carbachol; DNA-Binding Proteins; Early Growth Response Protein 1; Extracellular Space; Immediate-Early Proteins; Muscarinic Agonists; Oxotremorine; PC12 Cells; Phosphatidylinositol 4,5-Diphosphate; Protein Kinase C; Rats; Receptors, Muscarinic; RNA, Messenger; Transcription Factors | 1997 |
Muscarinic acetylcholine receptors on rat thymocytes: their possible involvement in DNA fragmentation.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Atropine; Binding, Competitive; Carbachol; DNA Fragmentation; Electrophoresis, Agar Gel; Hydrocortisone; Injections, Subcutaneous; Isotope Labeling; Male; Muscarinic Agonists; Muscarinic Antagonists; Nucleosomes; Oxotremorine; Piperidines; Quinuclidinyl Benzilate; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Thymus Gland | 1997 |
Exocytotic release from neuronal cell bodies, dendrites and nerve terminals in sympathetic ganglia of the rat, and its differential regulation.
Topics: Animals; Atropine; Carbachol; Cell Membrane; Dendrites; Exocytosis; Ganglia, Sympathetic; Male; Membrane Potentials; Nerve Endings; Neurons; Nicotine; Oxotremorine; Parasympatholytics; Pirenzepine; Potassium; Rats; Rats, Wistar; Receptors, Muscarinic; Regression Analysis; Synapses | 1997 |
Site-directed mutagenesis on the m2 muscarinic acetylcholine receptor: the significance of Tyr403 in the binding of agonists and functional coupling.
Topics: Acetylcholine; Animals; Binding Sites; Carbachol; CHO Cells; Cricetinae; Cyclic AMP; GTP-Binding Proteins; Kinetics; Muscarinic Agonists; Muscarinic Antagonists; Mutagenesis, Site-Directed; Mutation; Oxotremorine; Receptor, Muscarinic M2; Receptors, Muscarinic; Tyrosine | 1997 |
The relationship between agonist intrinsic activity and the rate of endocytosis of muscarinic receptors in a human neuroblastoma cell line.
Topics: Arecoline; Bethanechol; Carbachol; Endocytosis; Humans; Kinetics; Ligands; Methacholine Chloride; Muscarinic Agonists; Neuroblastoma; Oxotremorine; Pilocarpine; Receptor, Muscarinic M3; Receptors, Muscarinic; Tumor Cells, Cultured | 1998 |
Cholinergic mechanisms in the neurocontrol of the branchial heart of the cephalopod Sepia officinalis L.
Topics: Acetylcholine; Animals; Arecoline; Branchial Region; Bungarotoxins; Carbachol; Dose-Response Relationship, Drug; Heart; Hexamethonium; Mollusca; Muscarine; Nicotine; Oxotremorine; Pilocarpine; Receptors, Cholinergic; Tetraethylammonium; Tubocurarine | 1998 |
Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Acetylcholine; Animals; Atropine; Behavior, Animal; Carbachol; Cataplexy; Cholinergic Fibers; Dogs; Feeding Behavior; Female; GABA Agonists; Gallamine Triethiodide; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Muscimol; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Piperidines; Pirenzepine; Prosencephalon | 1998 |
Comparison of the effects of M1 and M2 muscarinic receptor activation in the absence of GABAergic inhibition in immature rat hippocampal CA3 area.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Bicuculline; Carbachol; Dose-Response Relationship, Drug; Epilepsy; Evoked Potentials; GABA Antagonists; GABA-A Receptor Antagonists; Hippocampus; In Vitro Techniques; Muscarinic Agonists; Oxotremorine; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic | 1998 |
Acetylcholine triggers L-glutamate exocytosis via nicotinic receptors and inhibits melatonin synthesis in rat pinealocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Acetylcholine; Animals; Arylamine N-Acetyltransferase; Atropine; Bungarotoxins; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cells, Cultured; Diltiazem; Exocytosis; Glutamic Acid; Melatonin; Muscarine; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Nifedipine; Nitrendipine; Oxotremorine; Parasympathetic Nervous System; Pineal Gland; Rats; Rats, Wistar; Receptors, Nicotinic; Scopolamine; Synaptic Vesicles; Tubocurarine | 1998 |
Ionic mechanism of the slow afterdepolarization induced by muscarinic receptor activation in rat prefrontal cortex.
Topics: Acetylcholine; Animals; Atropine; Carbachol; Cesium; Chelating Agents; Egtazic Acid; Male; Membrane Potentials; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Patch-Clamp Techniques; Potassium; Prefrontal Cortex; Pyramidal Cells; Rats; Rats, Inbred Strains; Receptors, Muscarinic; Sodium; Vasodilator Agents | 1998 |
Signaling mechanisms underlying muscarinic receptor-mediated increase in contraction rate in cultured heart cells.
Topics: Animals; Animals, Newborn; Atropine; Base Sequence; Carbachol; Cells, Cultured; Estrenes; GTP-Binding Proteins; Heart; Heart Ventricles; Isoproterenol; Muscarinic Agonists; Myocardial Contraction; Myocardium; Oligodeoxyribonucleotides, Antisense; Oxotremorine; Phosphatidylinositols; Polymerase Chain Reaction; Propranolol; Protein Isoforms; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; RNA, Messenger; Transcription, Genetic | 1998 |
Mutations of aspartate 103 in the Hm2 receptor and alterations in receptor binding properties of muscarinic agonists.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Alanine; Amino Acid Substitution; Animals; Arecoline; Asparagine; Aspartic Acid; Carbachol; COS Cells; Muscarinic Agonists; Mutagenesis, Site-Directed; Oxotremorine; Pilocarpine; Receptor, Muscarinic M2; Receptors, Muscarinic; Transfection | 1995 |
In vitro characterisation of the muscarinic receptor partial agonist, sabcomeline, in rat cortical and heart membranes.
Topics: Adenylyl Cyclases; Animals; Carbachol; Cell Membrane; Cells, Cultured; Cerebral Cortex; Drug Interactions; Heart; Imines; Male; Muscarinic Agonists; Muscarinic Antagonists; Muscle, Smooth, Vascular; Myocardium; Oxotremorine; Quinuclidines; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Sprague-Dawley | 1999 |
Distinct functional muscarinic receptors in guinea-pig gallbladder, ileum and atria.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Animals; Carbachol; Electric Stimulation; Female; Gallbladder; Guinea Pigs; Heart; Ileum; In Vitro Techniques; Male; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Myocardial Contraction; Oxotremorine; Rats; Rats, Wistar; Receptors, Muscarinic | 1999 |
Lack of effect of McN-A-343 on membrane current and contraction in guinea pig ventricular myocytes.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Adrenergic beta-Agonists; Animals; Calcium Channels; Calcium Channels, L-Type; Carbachol; Cell Membrane; Cyclic AMP; Electrophysiology; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Isoproterenol; Muscarinic Agonists; Myocardial Contraction; Oxotremorine; Patch-Clamp Techniques; Receptor, Muscarinic M1; Receptor, Muscarinic M2; Receptors, Muscarinic | 1999 |
Reduced high-affinity agonist binding at the M(1) muscarinic receptor in Alzheimer's disease brain: differential sensitivity to agonists and divalent cations.
Topics: Acetylcholine; Aged; Alzheimer Disease; Brain; Carbachol; Cations, Divalent; Chlorides; Edetic Acid; Female; Guanylyl Imidodiphosphate; Humans; Kinetics; Magnesium Chloride; Male; Manganese Compounds; Muscarinic Agonists; Oxotremorine; Pirenzepine; Receptor, Muscarinic M1; Receptors, Muscarinic; Reference Values | 1999 |
Inhibitory cholinergic effects on the autonomously contractile bulbus cordis branchialis of the cephalopod Sepia officinalis L.
Topics: Acetylcholine; Animals; Arecoline; Bungarotoxins; Carbachol; Cholinergic Agents; Cholinergic Agonists; Cholinergic Antagonists; Female; Heart; Male; Mollusca; Muscarine; Myocardial Contraction; Nicotine; Oxotremorine; Pilocarpine; Quinuclidinyl Benzilate | 1999 |
Muscarinic receptor heterogeneity in follicle-enclosed Xenopus oocytes.
Topics: Acetylcholine; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Female; Follicle Stimulating Hormone; Gene Expression; Membrane Potentials; Muscarinic Antagonists; Oocytes; Ovarian Follicle; Oxotremorine; Patch-Clamp Techniques; Piperidines; Pirenzepine; Receptors, Muscarinic; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Tropicamide; Xenopus laevis | 1999 |
A G protein gamma subunit-specific peptide inhibits muscarinic receptor signaling.
Topics: Amino Acid Sequence; Animals; Brain; Calcium; Calcium Channels; Carbachol; Cattle; Cells, Cultured; CHO Cells; Clonidine; Cricetinae; Cytoplasm; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; In Vitro Techniques; N-Methylscopolamine; Neurons; Oxotremorine; Peptide Fragments; Receptor, Muscarinic M4; Receptors, Adrenergic, alpha-2; Receptors, Muscarinic; Receptors, Somatostatin; Signal Transduction; Spinal Cord; Superior Cervical Ganglion; Transfection | 1999 |
Activation of muscle nicotinic acetylcholine receptor channels by nicotinic and muscarinic agonists.
Topics: Animals; Carbachol; Dose-Response Relationship, Drug; Humans; Ion Channels; Kinetics; Mice; Muscarine; Muscarinic Agonists; Muscle, Skeletal; Neurons; Nicotine; Nicotinic Agonists; Oxotremorine; Rats; Receptors, Nicotinic; Recombinant Proteins; Structure-Activity Relationship | 1999 |
Carbachol and acetylcholine delay the early postdenervation depolarization of muscle fibres through M1-cholinergic receptors.
Topics: Acetylcholine; Animals; Arecoline; Atropine; Carbachol; Culture Techniques; Diaphragm; Male; Membrane Potentials; Muscarinic Agonists; Muscarinic Antagonists; Muscle Denervation; Muscle Fibers, Skeletal; Oxotremorine; Piperidines; Pirenzepine; Rats; Rats, Wistar; Receptor, Muscarinic M1; Receptors, Muscarinic | 2000 |
Effects of microdialyzed oxotremorine, carbachol, epibatidine, and scopolamine on intraspinal release of acetylcholine in the rat.
Topics: Acetylcholine; Animals; Bridged Bicyclo Compounds, Heterocyclic; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Male; Microdialysis; Oxotremorine; Pyridines; Rats; Rats, Sprague-Dawley; Scopolamine; Spinal Cord | 2000 |
[Muscarinic receptors in the neostriatum--participation in the operant behavior regulation in dogs].
Topics: Animals; Carbachol; Cognition; Conditioning, Operant; Dogs; Escape Reaction; Functional Laterality; Microinjections; Motor Activity; Muscarinic Agonists; Muscarinic Antagonists; Neostriatum; Oxotremorine; Posture; Reaction Time; Receptors, Muscarinic; Scopolamine | 2000 |
Coincident signalling between the Gi/Go-coupled delta-opioid receptor and the Gq-coupled m3 muscarinic receptor at the level of intracellular free calcium in SH-SY5Y cells.
Topics: Animals; Calcium; Carbachol; CHO Cells; Cricetinae; Enkephalin, D-Penicillamine (2,5)-; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; Heterotrimeric GTP-Binding Proteins; Humans; Kinetics; Neuroblastoma; Oxotremorine; Receptor Cross-Talk; Receptor, Muscarinic M3; Receptors, Muscarinic; Receptors, Opioid, delta; Transfection; Tumor Cells, Cultured | 2001 |
Investigations into the physiological role of muscarinic M2 and M4 muscarinic and M4 receptor subtypes using receptor knockout mice.
Topics: Animals; Carbachol; Cerebral Cortex; Heart; Heart Rate; Humans; Hypothermia; Male; Mice; Mice, Knockout; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Radioligand Assay; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, Muscarinic; Salivation; Tremor | 2001 |
Pharmacological characterization of muscarinic receptors in mouse isolated urinary bladder smooth muscle.
Topics: Acetylcholine; Animals; Carbachol; Diamines; Dioxolanes; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Muscle Contraction; Muscle, Smooth; Oxotremorine; Pilocarpine; Piperidines; Receptors, Muscarinic; Urinary Bladder | 2001 |
Effects of N-ethylmaleimide on conformational equilibria in purified cardiac muscarinic receptors.
Topics: Animals; Blotting, Western; Carbachol; Cell Line; Enzyme Inhibitors; Ethylmaleimide; Humans; Insecta; Kinetics; Ligands; Models, Chemical; Muscarinic Agonists; N-Methylscopolamine; Oxotremorine; Parasympatholytics; Precipitin Tests; Protein Binding; Protein Conformation; Quinuclidinyl Benzilate; Receptor, Muscarinic M2; Receptors, Muscarinic; Sulfhydryl Reagents; Swine; Time Factors | 2002 |
PMA decreases the proliferation of retinal cells in vitro: the involvement of acetylcholine and BDNF.
Topics: Acetylcholine; Alkaloids; Amacrine Cells; Animals; Atropine; Benzophenanthridines; Brain-Derived Neurotrophic Factor; Calcium; Carbachol; Cell Division; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Eye Proteins; Growth Inhibitors; Isoenzymes; MAP Kinase Signaling System; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Phenanthridines; Pirenzepine; Protein Kinase C; Rats; Receptor, Muscarinic M1; Receptors, Muscarinic; Retina; Signal Transduction; Tetradecanoylphorbol Acetate | 2003 |
Role of muscarinic receptors in the activation of the ventral subiculum and the consequences for dopamine release in the nucleus accumbens.
Topics: Animals; Atropine; Bicuculline; Bridged-Ring Compounds; Carbachol; Cholinergic Agonists; Diamines; Dopamine; Hippocampus; Male; Microdialysis; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nucleus Accumbens; Oxotremorine; Pilocarpine; Pyridines; Rats; Receptors, Muscarinic; Spiro Compounds; Thiadiazoles; Tropanes | 2003 |
Cholinergic regulation of pericyte-containing retinal microvessels.
Topics: Acetylcholine; Animals; Calcium; Capillaries; Carbachol; Electric Stimulation; Fluorescent Dyes; Fura-2; Gap Junctions; In Vitro Techniques; Ion Channels; Membrane Potentials; Muscarinic Agonists; Muscle Contraction; Muscle, Smooth, Vascular; Neurotransmitter Agents; Oxotremorine; Parasympathetic Nervous System; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Retinal Vessels; Signal Transduction | 2003 |
A beta-induced TNF-alpha expression and acetylcholine action in mouse glial cells.
Topics: Acetylcholine; Amyloid beta-Peptides; Animals; Carbachol; Cells, Cultured; Glyceraldehyde-3-Phosphate Dehydrogenases; Inflammation; Mice; Muscarinic Agonists; Neuroglia; Nicotine; Nicotinic Agonists; Oxotremorine; Peptide Fragments; Reverse Transcriptase Polymerase Chain Reaction; Tumor Necrosis Factor-alpha | 2003 |
Receptor mechanisms mediating cyanide generation in PC12 cells and rat brain.
Topics: Analysis of Variance; Animals; Atropine; Brain; Carbachol; Cells, Cultured; Cholinergic Agonists; Cyanides; Drug Interactions; Embryo, Mammalian; Hydromorphone; Morphine; Muscarinic Agonists; Muscarinic Antagonists; Naloxone; Narcotic Antagonists; Narcotics; Oxotremorine; PC12 Cells; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface | 2004 |
Cholinergic regulation of the evoked quantal release at frog neuromuscular junction.
Topics: Acetylcholine; Action Potentials; Animals; Arecoline; Carbachol; Cholinergic Agonists; Diamines; Motor Neurons; Muscarinic Agonists; Muscarinic Antagonists; Neural Conduction; Neuromuscular Junction; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Oxotremorine; Parasympatholytics; Pirenzepine; Rana ridibunda; Receptors, Muscarinic; Synaptic Transmission; Tubocurarine | 2004 |
Pharmacological profiles of an anticholinergic agent, phencynonate hydrochloride, and its optical isomers.
Topics: Animals; Aza Compounds; Binding, Competitive; Carbachol; Cerebral Cortex; Cholinergic Antagonists; Female; Glycolates; Guinea Pigs; Hypnotics and Sedatives; Male; Mice; Muscle Contraction; Oxotremorine; Pentobarbital; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Receptors, Muscarinic; Salivation; Sleep; Stereoisomerism | 2005 |
Differential effects on [35S]GTPgammaS binding using muscarinic agonists and antagonists in the gerbil brain.
Topics: Acetylcholine; Animals; Binding, Competitive; Brain; Brain Chemistry; Carbachol; Dose-Response Relationship, Drug; Gerbillinae; Guanosine 5'-O-(3-Thiotriphosphate); Male; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Radioligand Assay; Receptor, Muscarinic M2; Receptor, Muscarinic M4; Receptors, G-Protein-Coupled; Receptors, Muscarinic; Sulfur Radioisotopes; Synaptic Transmission | 2005 |
Comparative study on pharmacological effects of DM-phencynonate hydrochloride and its optical isomers.
Topics: Animals; Aza Compounds; Binding, Competitive; Carbachol; Cerebral Cortex; Female; Glycolates; Guinea Pigs; Male; Mice; Muscle Contraction; Oxotremorine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Wistar; Salivation; Stereoisomerism | 2005 |
Regulation of Kv7 (KCNQ) K+ channel open probability by phosphatidylinositol 4,5-bisphosphate.
Topics: Animals; Carbachol; CHO Cells; Cholinergic Agonists; Cloning, Molecular; Cricetinae; Cricetulus; Dose-Response Relationship, Drug; Electric Stimulation; Extracellular Space; Green Fluorescent Proteins; Humans; Ion Channel Gating; KCNQ Potassium Channels; Membrane Potentials; Muscarinic Agonists; Oncogene Protein v-akt; Oxotremorine; Patch-Clamp Techniques; Phosphatidylinositol 4,5-Diphosphate; Phospholipase C gamma; Phosphotransferases (Alcohol Group Acceptor); Probability; src-Family Kinases; Structure-Activity Relationship; Transfection | 2005 |
Estimation of agonist activity at G protein-coupled receptors: analysis of M2 muscarinic receptor signaling through Gi/o,Gs, and G15.
Topics: (4-(m-Chlorophenylcarbamoyloxy)-2-butynyl)trimethylammonium Chloride; Algorithms; Animals; Carbachol; Cell Line; CHO Cells; Colforsin; Cricetinae; Cricetulus; Cyclic AMP; Diphenylacetic Acids; GTP-Binding Protein alpha Subunits, Gi-Go; GTP-Binding Protein alpha Subunits, Gq-G11; GTP-Binding Protein alpha Subunits, Gs; Heterotrimeric GTP-Binding Proteins; Humans; Isoproterenol; Oxotremorine; Pertussis Toxin; Phosphatidylinositols; Piperidines; Pirenzepine; Quinuclidines; Receptor, Muscarinic M2; Signal Transduction; Transfection | 2007 |
An optical dynamic mass redistribution assay reveals biased signaling of dualsteric GPCR activators.
Topics: Acetylcholine; Animals; Atropine; Biosensing Techniques; Carbachol; Cell Line; CHO Cells; Cholinergic Agonists; Cricetinae; Cricetulus; Drug Evaluation, Preclinical; Muscarinic Agonists; Muscarinic Antagonists; Oxotremorine; Receptors, G-Protein-Coupled; Signal Transduction | 2009 |
Receptor-mediated suppression of potassium currents requires colocalization within lipid rafts.
Topics: Animals; Blotting, Western; Calcium; Carbachol; Cell Line; Cholinergic Agents; Ganglia, Spinal; Humans; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Membrane Microdomains; Membrane Potentials; Mice; Muscarine; Oxotremorine; Phosphatidylinositol 4,5-Diphosphate; Potassium Channel Blockers; Potassium Channels; Receptor, Muscarinic M1; Receptor, Muscarinic M3; Receptors, Muscarinic | 2009 |
A simple method for quantifying functional selectivity and agonist bias.
Topics: Animals; Carbachol; CHO Cells; Cricetinae; Cricetulus; Guinea Pigs; Ileum; Organ Culture Techniques; Oxotremorine; Receptors, Cytoplasmic and Nuclear | 2012 |
Cholinergic regulation of epithelial sodium channels in rat alveolar type 2 epithelial cells.
Topics: Alveolar Epithelial Cells; Amides; Animals; Atropine; Carbachol; Cells, Cultured; Enzyme Activation; Epithelial Sodium Channel Agonists; Epithelial Sodium Channels; Membrane Potentials; Mice; Mice, Inbred C57BL; Muscarinic Agonists; Muscarinic Antagonists; Nicotine; Nicotinic Agonists; Oxotremorine; Patch-Clamp Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M2; Receptor, Muscarinic M3; rho-Associated Kinases; rhoA GTP-Binding Protein | 2013 |
Cholinergic manipulations bidirectionally regulate object memory destabilization.
Topics: Acetylcholine; Animals; Carbachol; Cerebral Cortex; Male; Muscarinic Agonists; Muscarinic Antagonists; Neuropsychological Tests; Oxotremorine; Rats, Long-Evans; Receptors, Muscarinic; Recognition, Psychology; Scopolamine | 2015 |
Classical and atypical agonists activate M1 muscarinic acetylcholine receptors through common mechanisms.
Topics: Animals; Binding Sites; Calcium; Carbachol; Cell Membrane; CHO Cells; Cricetinae; Cricetulus; Inositol Phosphates; Models, Molecular; Muscarinic Agonists; Mutation; Oxotremorine; Pyridines; Receptor, Muscarinic M1; Receptors, G-Protein-Coupled; Thiadiazoles | 2015 |
Muscarinic modulation of M and h currents in gerbil spherical bushy cells.
Topics: Animals; Carbachol; Cholinergic Fibers; Cochlear Nucleus; Gerbillinae; Membrane Potentials; Muscarinic Agonists; Oxotremorine; Patch-Clamp Techniques; Receptors, Muscarinic | 2020 |